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Comparing Cytological Adequacy Between Conventional Smear And Liquid-Based Cytology In Ultrasound-Guided Fine Needle Aspiration Of Thyroid Nodules: A Prospective Study, Nattachai Kruajak, Pawanrat Kranokpiraksa, Tikamporn Jitpasutham
Comparing Cytological Adequacy Between Conventional Smear And Liquid-Based Cytology In Ultrasound-Guided Fine Needle Aspiration Of Thyroid Nodules: A Prospective Study, Nattachai Kruajak, Pawanrat Kranokpiraksa, Tikamporn Jitpasutham
Chulalongkorn Medical Journal
Background: The major problem of conventional smear for ultrasound-guided fine needle aspiration (FNA) of thyroid nodules is the sample inadequacy. Liquid-based cytology (LBC) is claimed to perform better than the conventional smear (CS) in reducing sample inadequacy. However, the evidence of better adequacy in LBC is unclear. Objective: This study is the first prospective study aiming to compare sample adequacy in CS and LBC using ThinPrep system with adequacy criteria based on the 2017 Bethesda System for Reporting Thyroid Cytopathology. Methods: One hundred and twenty thyroid nodules were prospectively recruited for ultrasound-guided FNA from March to September 2019. The sample …