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Full-Text Articles in Medicine and Health Sciences

The Relationship Between Ultra-Processed Food (Upf) Consumption, Sedentary Behavior, And Overweight Status Among Students At Sman 1 Tangerang, Banten, Indonesia, Husna Dzakya Azzahra, Zenia Elsa Fitri, Imas Arumsari Apr 2025

The Relationship Between Ultra-Processed Food (Upf) Consumption, Sedentary Behavior, And Overweight Status Among Students At Sman 1 Tangerang, Banten, Indonesia, Husna Dzakya Azzahra, Zenia Elsa Fitri, Imas Arumsari

Indonesian Journal of Public Health Nutrition (IJPHN)

Overweight is a condition where excess body fat accumulates, leading to increased risks of diseases such as heart disease, stroke, diabetes, hypertension, arthritis, and cancer. The prevalence of overnutrition in adolescents aged 16-18 years has been rising over the years, from 5.7% in 2013 to 9.5% in 2018. This study aims to analyze the relationship between Ultra-Processed Food (UPF) consumption and sedentary behavior on overweight status among students at SMAN 1 Tangerang. A cross-sectional design, data were collected through interviews with 114 respondents using the SQ-FFQ Ultra-Processed Food questionnaire and the Sedentary Behavior Questionnaire (SBQ), with quota sampling employed. The …


Cross-Cultural Adaptation And Psychometric Validation Of The Medication Compliance Questionnaire (Mcq) For Type 2 Diabetes Mellitus Patients In Indonesia, Much Ilham Novalisa Aji Wibowo, Angelia Yuliana Safitri, Didik Setiawan Apr 2025

Cross-Cultural Adaptation And Psychometric Validation Of The Medication Compliance Questionnaire (Mcq) For Type 2 Diabetes Mellitus Patients In Indonesia, Much Ilham Novalisa Aji Wibowo, Angelia Yuliana Safitri, Didik Setiawan

Makara Journal of Health Research

Background: Medication adherence is critical for managing type 2 diabetes mellitus (T2DM). The Medication Compliance Questionnaire (MCQ) is a widely recognized tool for assessing adherence but has not been adapted for T2DM in Indonesia. This study aimed to adapt and validate the MCQ in the Indonesian socio-cultural context.

Methods: A cross-sectional study at community health centers (May–Aug 2024) involved forward/back translation, content validation using Aiken’s V, and psychometric assessment among 230 patients. Exploratory Factor Analysis (EFA) assessed construct validity, including convergent, discriminant, and reliability.

Results: Aiken's V index indicated strong content validity (average = 0.881). EFA identified …


The Effect Of Nursing Students' Level Of Readiness For Professional Practice On Self-Efficacy And Clinical Stress Perception: A Cross-Sectional Study, Uğur Öner, Dilek Yılmaz, Sinan Aslan, Ercan Çınar Apr 2025

The Effect Of Nursing Students' Level Of Readiness For Professional Practice On Self-Efficacy And Clinical Stress Perception: A Cross-Sectional Study, Uğur Öner, Dilek Yılmaz, Sinan Aslan, Ercan Çınar

Makara Journal of Health Research

Background: It is essential to evaluate students’ readiness before graduation and support them with education accordingly. This study investigates the effect of the level of readiness for professional practice as a purpose on the self-efficacy and clinical stress perceptions of nursing students.

Methods: The data for this cross-sectional study were collected between May and July 2024. The study included 733 3rd and 4th-year students studying nursing departments at state universities in Turkey. The Student Identification Form, Casey-Fink Readiness for Practice Scale (CFRPS), Student Self-Efficacy Scale (SSS), and Nursing Students Perceptions of Clinical Stressors Scale (NSPCSS) were used.

Results …


Knowledge, Attitudes, And Practices Of Adults For Periodic Health Assessment In Al Ahsa, Saudi Arabia, Fatimah Yousef Alhafedh, Rawan Ahmed Almusaileem, Zahraa Hassan Aljaafar, Rayhanah Saleh Alaayesh, Edric Estrella Apr 2025

Knowledge, Attitudes, And Practices Of Adults For Periodic Health Assessment In Al Ahsa, Saudi Arabia, Fatimah Yousef Alhafedh, Rawan Ahmed Almusaileem, Zahraa Hassan Aljaafar, Rayhanah Saleh Alaayesh, Edric Estrella

Makara Journal of Health Research

Background: Regular medical consultation, such as annually or semi-annually for check-ups, especially to diagnose chronic conditions, is essential for health maintenance, particularly in adults. The aim of this study is to analyze the knowledge, attitudes, and practices of adults aged 30 years or older for obtaining periodic professional health assessment in the city of Al Ahsa in Saudi Arabia.

Methods: A cross-sectional study was conducted in a total sample of 472 adults. Multistage sampling was employed, and data were collected using a Google Forms survey and analyzed using JASP and OpenEpi. Descriptive and logistic regression analysis was used …


Health Literacy, Health Perception, And Influencing Factors Among Immigrants, Canan Birimoglu Okuyan, Ebru Deveci, Fatma Karasu Apr 2025

Health Literacy, Health Perception, And Influencing Factors Among Immigrants, Canan Birimoglu Okuyan, Ebru Deveci, Fatma Karasu

Makara Journal of Health Research

Background: Individuals living in rural areas face several healthcare disadvantages, including limited access to medical facilities and specialists during emergencies. This study examines healthy lifestyle behaviors, health perceptions, and influencing factors among immigrants in a rural region of southern Türkiye.

Methods: This cross-sectional study involved immigrants registered at a family health center. Data were collected using a sociodemographic questionnaire, the Perception of Health Scale, and the Health Literacy Scale.

Results: Statistically significant differences in THLS-32 scores were found based on participants’ occupation, marital status, and education level (p < 0.05). A moderately positive correlation was observed between health literacy and health perception scores (p < 0.05).

Conclusions: Research on the relationship between …


Impact Of Pandemic-Driven Parental Fear On Childhood Immunization Rates: Examining Attitudes Toward Vaccination During Crisis Periods In Türkiye, Özüm Erkin, İlknur Göl Apr 2025

Impact Of Pandemic-Driven Parental Fear On Childhood Immunization Rates: Examining Attitudes Toward Vaccination During Crisis Periods In Türkiye, Özüm Erkin, İlknur Göl

Makara Journal of Health Research

Background: This study aimed to investigate the effect of parents’ fear of coronavirus on their attitudes towards the vaccination of their children.

Methods: The study was conducted with 2,350 parents who were selected by using the snowball sampling method. The questionnaire included a personal information form, the Public Attitude towards Vaccination Scale – Health Belief Model, and the Fear of COVID-19 Scale.

Results: The scores of the study group from the sub-dimensions of the Public Attitude towards Vaccination Scale Health Belief Model were as follows: 17.39 ± 2.92 perceived susceptibility, 16.74 ± 3.19 perceived severity, 21.10 ± …


Assessing Healthcare Students’ Self-Efficacy In Disaster Response: A Cross-Sectional Analysis, Aydın Şenol, Abdülkerim Adıyaman, Canan Birimoglu Okuyan Apr 2025

Assessing Healthcare Students’ Self-Efficacy In Disaster Response: A Cross-Sectional Analysis, Aydın Şenol, Abdülkerim Adıyaman, Canan Birimoglu Okuyan

Makara Journal of Health Research

Background: Assessing healthcare students’ self-efficacy in disaster response is crucial for preparing them to effectively manage real-world disaster situations. This study aimed to assess the self-efficacy status of healthcare students in disaster response.

Methods: The data for this cross-sectional analysis were gathered from 498 healthcare students between November 18, 2023, and February 14, 2024, using an individual diagnostic form and the disaster-response self-efficacy (DRSE) scale. This scale is used to assess an individual’s self-efficacy in responding effectively to disasters, including on-site rescue competency, disaster psychological nursing competency, disaster role quality, and adaptation competency.

Results: The mean age …


Cross-Cultural Adaptation And Expert Opinion Of Revised Trauma Quality Of Life Questionnaire (Rt-Qol): Malay Language Version, Sharifa Ezat Wan Puteh, Shamsinar Ibrahim, Malina Zulkifli, Azimatun Noor Aizuddin, Hanizah Mohd Yusoff Apr 2025

Cross-Cultural Adaptation And Expert Opinion Of Revised Trauma Quality Of Life Questionnaire (Rt-Qol): Malay Language Version, Sharifa Ezat Wan Puteh, Shamsinar Ibrahim, Malina Zulkifli, Azimatun Noor Aizuddin, Hanizah Mohd Yusoff

Makara Journal of Health Research

Background: This study examines the cross-cultural adaptation and expert validation of the Revised Trauma Quality of Life (RT-QOL) questionnaire, translating it from English to Malay.

Methods: The study employed Beaton’s adaptation guidelines and Takasaki’s framework for expert opinions, involving 51 road traffic injury patients recruited from the Emergency and Trauma Department (ED) of a public hospital in Kedah, Malaysia, from March to June 2022. Participants were contacted via telephone 30 days after their hospital visit regarding their involvement in the study. Three independent experts, comprising academicians in healthcare and emergency department clinicians, reviewed and reconciled the RT-QOL Malay …


Knowledge, Attitudes, And Motivation Regarding Exclusive Breastfeeding Between Medical And Nonmedical Students: A Cross-Sectional Study, Melviana Lubis, Meisyah Putri Rozi Apr 2025

Knowledge, Attitudes, And Motivation Regarding Exclusive Breastfeeding Between Medical And Nonmedical Students: A Cross-Sectional Study, Melviana Lubis, Meisyah Putri Rozi

Makara Journal of Health Research

Background: Exclusive breastfeeding provides substantial health benefits; however, disparities in knowledge and support persist. This study aimed to compare knowledge levels, attitudes, and motivation levels regarding exclusive breastfeeding between female medical and nonmedical students.

Methods: A cross-sectional survey was conducted at Universitas Muhammadiyah Sumatera Utara and involved 314 students from the 2023 cohort. A validated questionnaire was used to assess knowledge levels (16 items), attitude (IIFAS, 16 items), and motivation (15 items). Data were analyzed using the chi-square test, odds ratio (OR), and Spearman’s correlation.

Results: Medical students demonstrated significantly higher levels of knowledge (OR = 3.50; …


Prevalence Of Peri-Implantitis And Assessment Of Oral Health-Related Quality Of Life Among Patients With Dental Implants At Hospital Universiti Sains Malaysia, Esther Li-Ching Ang, Zurairah Berahim, Normastura Abd Rahman, Akram Hassan, Siti Lailatul Akmar Zainuddin Apr 2025

Prevalence Of Peri-Implantitis And Assessment Of Oral Health-Related Quality Of Life Among Patients With Dental Implants At Hospital Universiti Sains Malaysia, Esther Li-Ching Ang, Zurairah Berahim, Normastura Abd Rahman, Akram Hassan, Siti Lailatul Akmar Zainuddin

Journal of Dentistry Indonesia

Patient-reported outcomes about peri-implantitis are lacking among the Asian population, impacting decision-making in dental implant therapy. Objectives: This study aimed to assess the prevalence of peri-implantitis among Malaysian adults, and its impact on oral health-related quality of life (OHRQoL). Methods: Randomly selected 105 participants (adults aged 18 and above) having 265 implants were examined and diagnosed as with or without peri-implantitis (PI). Clinical examinations, including peri-implant probing depth, bleeding, and suppuration on probing with radiographic bone loss, were used to determine peri-implant status. OHRQoL of all participants were recorded using the short version of the Malaysian Oral Health Impact Profile …


Evaluation Of Dentistry Students' Perceptions And Attitudes Towards Artificial Intelligence In Kazakhstan, Yasin Yasa, Kubeisin Altynbekov, Nazgul Onaibekova Apr 2025

Evaluation Of Dentistry Students' Perceptions And Attitudes Towards Artificial Intelligence In Kazakhstan, Yasin Yasa, Kubeisin Altynbekov, Nazgul Onaibekova

Journal of Dentistry Indonesia

Objective: Artificial intelligence’s (AI) potential to analyze medical data and improve patient outcomes is driving its rapid integration into healthcare systems. This study addresses the knowledge gap regarding Kazakhstani dental students’ attitudes toward AI in dentistry. Methods: A survey with 213 participants assessed dental students’ views on AI in dentistry at two Kazakhstani universities. A self-administered questionnaire (22 items) via Google Forms was used to gather data on demographics, baseline knowledge (information sources, understanding of AI principles, and familiarity with dental AI applications), and attitudes/perceptions. Frequency analyses and chi-square tests (p < 0.05) explored the responses. Results: The survey included 213 dental students (mean …


Synthesis And Partial Characterization Of Chitosan Phosphorylation From Marine Cuttlefish Sepia Aculeata (Orbingy, 1848) And Its Antimicrobial Potentials Against Oral Pathogens, Yathin Reddy Putta, Annathai Pitchai, Pasiyappazham Ramasamy Apr 2025

Synthesis And Partial Characterization Of Chitosan Phosphorylation From Marine Cuttlefish Sepia Aculeata (Orbingy, 1848) And Its Antimicrobial Potentials Against Oral Pathogens, Yathin Reddy Putta, Annathai Pitchai, Pasiyappazham Ramasamy

Journal of Dentistry Indonesia

Objectives: This study investigated the synthesis and partial characterization of phosphorylated chitosan extracted from the cuttlebone of Sepia aculeata (Orbingy, 1848) and evaluated its antimicrobial potential against oral pathogens. Methods: The synthesis of phosphorylated chitosan from Sepia aculeata cuttlebone involved several steps: cleaning, deproteinization, demineralization to extract chitin, deacetylation to produce chitosan, and phosphorylation to introduce phosphate groups. Phosphorylation enhances the properties of chitosan, making it a promising candidate for oral health applications. Phosphorylated chitosan was purified and characterized using Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), and Scanning Electron Microscopy (SEM) to confirm structural changes. This process enhances …


Changes In Craniofacial Morphology Of Class Iii Malocclusion Treated Using Facemask Or Active Skeletonized Sutural Distractor Appliance, Wael Ahmed Bayomy Mohamed, Rozita Hassan, Norma Ab Rahman, Shaifulizan Ab Rahman, Norkhafizah Saddki Apr 2025

Changes In Craniofacial Morphology Of Class Iii Malocclusion Treated Using Facemask Or Active Skeletonized Sutural Distractor Appliance, Wael Ahmed Bayomy Mohamed, Rozita Hassan, Norma Ab Rahman, Shaifulizan Ab Rahman, Norkhafizah Saddki

Journal of Dentistry Indonesia

Objective: This research compared the effectiveness of the Active Skeletonized Sutural Distractor (ASSD) and the face mask (FM) in treating adolescent Class III malocclusion and assessed the stability of the mini screw utilized in the ASSD appliance. Methods: A total of 68 adolescents with Class III malocclusion were divided into either one of two treatment groups (ASSD or FM) for a maximum period of six months of therapy. Lateral cephalometric radiographs and impressions were taken for comparative purposes. The 3M® intra-oral elastic (USA) was attached to the mini-implant, and the mini-screw mobility was evaluated monthly using a force gauge …


Evaluation Of Mandibular Condyle And Coronoid Process Anomalies Using Cone-Beam Computed Tomography, Rümeysa Şendişçi Gök, Bilay Stevanovic Sancar, Sevcihan Günen Yılmaz Apr 2025

Evaluation Of Mandibular Condyle And Coronoid Process Anomalies Using Cone-Beam Computed Tomography, Rümeysa Şendişçi Gök, Bilay Stevanovic Sancar, Sevcihan Günen Yılmaz

Journal of Dentistry Indonesia

Objective: The aim of this study was to evaluate the prevalence of condylar and coronoid process anomalies, their types, and their relationship to sex. Method: Cone-beam computed tomography (CBCT) images were retrospectively analyzed for the presence and types of abnormalities in the condylar and coronoid processes. Statistical analysis of measurement data was performed using SPSS version 22. Medical histories of the individuals were obtained from their digital dental records. Results: CBCT images of 400 individuals were included in the study. Condylar anomalies were observed in 9.5% of cases, while coronoid anomalies were found in 7.5%. All condylar anomalies were more …


Different Effects Between Trigeminal Sensory And Vagal Visceral Input On Salivary Gland Blood Flow, Ratna Ramadhani, Toshiya Sato, Hisayoshi Ishii Apr 2025

Different Effects Between Trigeminal Sensory And Vagal Visceral Input On Salivary Gland Blood Flow, Ratna Ramadhani, Toshiya Sato, Hisayoshi Ishii

Journal of Dentistry Indonesia

Objective: The purpose of the present study was to evaluate the different effects of trigeminal sensory and vagal-visceral inputs on blood flow (BF) in the submandibular gland (SMG). Methods: Ten to eleven-week-old Wistar rats were anesthetized with urethane (1.0 g/kg) and artificially ventilated. The femoral artery was cannulated for systemic arterial blood pressure (SABP) measurement. The cervical sympathetic trunk (CST) on both sides and the cervical vagus nerve (CVN) on the right side were cut before the stimulation of the left abdominal vagus nerve (AVN). The CVN and lingual nerve (LN) were stimulated after cutting the CST and CVN. AVN, …


Exploring Research Trends In Endocrown Restorations: A Bibliometric Analysis Using Scopus Database, Nor Faharina Abdul Hamid, Nora Sakina Mohd Noor, Nor Azlida Mohd Nor Apr 2025

Exploring Research Trends In Endocrown Restorations: A Bibliometric Analysis Using Scopus Database, Nor Faharina Abdul Hamid, Nora Sakina Mohd Noor, Nor Azlida Mohd Nor

Journal of Dentistry Indonesia

Objectives: This study evaluates the scientific outcomes of endocrown research in terms of publication patterns, prominent publishing authors and countries, highly cited articles, and high-impact keywords using bibliometric analysis. Methods: A search was conducted in the Elsevier Scopus database for articles related to endocrowns using the query TS = “endocrown” OR “endo-crown” OR “endo crown*”. Analysis and visualization of the relevant literature and their publication data were performed using MS Excel, VOSviewer, and Biblioshiny. Results: Endocrown research has shown a steady annual growth of 15.23% since 1999, indicating a growing interest and focus in this area. Brazil was ranked among …


Microstructural And Elemental Characterization Of Hydrated Carbonated Hydroxyapatite As Pulp Capping Agent: An In Vitro Study, S.Swathi Priyadharshini, Chinnasamy Ragavendran, J. Ramana Ramya, Anand Sherwood Apr 2025

Microstructural And Elemental Characterization Of Hydrated Carbonated Hydroxyapatite As Pulp Capping Agent: An In Vitro Study, S.Swathi Priyadharshini, Chinnasamy Ragavendran, J. Ramana Ramya, Anand Sherwood

Journal of Dentistry Indonesia

Understanding the microstructural and elemental composition of pulp capping materials is crucial for predicting their biocompatibility and effectiveness in promoting pulp healing. Objectives: This study aimed to characterize the microstructural and elemental properties of carbonated hydroxyapatite as a dental pulp-capping material. Methods: Carbonated hydroxyapatite was synthesized using the precipitation method. MTA and Apacal ART were obtained from commercial sources. The materials were prepared into disk-shaped specimens, hydrated in deionized water at 37°C for 14 days, and analyzed using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Results: SEM images revealed that MTA exhibited smooth, plate-like crystalline structures surrounded by …


Compound Odontoma In A Child With Orthodontic Management Of An Impacted Maxillary Central Incisor: A Case Report, Sonika Achalli, Murali Patla, Jagadish Chandra, Ishika Sinha, Joseph Sebastian Apr 2025

Compound Odontoma In A Child With Orthodontic Management Of An Impacted Maxillary Central Incisor: A Case Report, Sonika Achalli, Murali Patla, Jagadish Chandra, Ishika Sinha, Joseph Sebastian

Journal of Dentistry Indonesia

Odontomes are the most common type of odontogenic tumors. Odontomes are of two major types i.e, complex and compound odontoma. They are usually asymptomatic and, hence, are seen as accidental findings on a radiograph. They may be associated with an unerupted or delayed eruption of a permanent tooth. Usually, odontomes are diagnosed at an early age. This case report provides a case of compound odontoma causing impaction of the right maxillary central incisor with its clinical, radiographic, and histopathologic features and its management. Case report: Here, a 13-year-old patient reported with unerupted maxillary central incisor on the right side. Clinical …


Does Periodontal Treatment During Pregnancy Reduce The Incidence Of Preterm Birth Rates?: A Meta-Analysis Of Randomized Controlled Trials, Ashraf Elzer, Raga A. Elzahaf, Hameda Asrafel, Khalid Sassi, Mohamed Jedeh Apr 2025

Does Periodontal Treatment During Pregnancy Reduce The Incidence Of Preterm Birth Rates?: A Meta-Analysis Of Randomized Controlled Trials, Ashraf Elzer, Raga A. Elzahaf, Hameda Asrafel, Khalid Sassi, Mohamed Jedeh

Journal of Dentistry Indonesia

Objective: To find out if scaling and root planing for periodontal disease during pregnancy lowers the incidence of preterm births. Methods: This is a meta-analysis study design; searches were conducted in the PubMed database and on Google Scholar between January 2000 and December 2023. Only randomized controlled trials (RCTs) were considered. The studies will be examined to determine the relationship between non-surgical periodontal treatment and preterm birth rates among pregnant women. Results: Only 14 trials were included out of 194 articles identified. The overall result indicated a statistically significant reduction in preterm birth rate when we use the random …


Intermittent Fasting And Cardiometabolic Health In Adults With Obesity: A Scoping Review, Tri Siswati, Lathifa Zahra Putri Nugroho, Natasya Nurul Gina, Almira Sitasari, Agus Wijanarka Apr 2025

Intermittent Fasting And Cardiometabolic Health In Adults With Obesity: A Scoping Review, Tri Siswati, Lathifa Zahra Putri Nugroho, Natasya Nurul Gina, Almira Sitasari, Agus Wijanarka

Indonesian Journal of Public Health Nutrition (IJPHN)

Obesity is a significant global health challenge, with adverse impacts on cardiometabolic health such as hypertension, dyslipidemia, and insulin resistance. One promising intervention in obesity management is intermittent fasting (PI). However, scientific evidence on the impact of IF on cardiometabolic health is still limited. This study used a scoping review design to evaluate the association between IF and cardiometabolic health in obese adults. Reference sources are available in English at least abstract between 2015–2023 as well as from PubMed and Google Scholar web sources. The search keywords on PubMed are "Adult AND intermittent fasting AND cardiometabolic" and on Google Scholar …


Exploring The Non-Communicable Disease Burden In Indonesia – Findings From The 2023 Health Survey, Akifa Laila Rusyda Apr 2025

Exploring The Non-Communicable Disease Burden In Indonesia – Findings From The 2023 Health Survey, Akifa Laila Rusyda

Indonesian Journal of Public Health Nutrition (IJPHN)

The present study rigorously examines the correlation between obesity, high-risk dietary consumption, and unhealthy lifestyles with the prevalence of non-communicable diseases (NCDs) in Indonesia. The study employed a cross-sectional study design using secondary data from the 2023 Indonesian Health Survey, analyzing 38 units (n) representing Indonesia's provinces in 2023. The correlation analysis, conducted using Pearson's test with a significance level of 95% (α<0.05), revealed significant regional disparities in the prevalence of NCDs, dietary consumption, and lifestyle factors across Indonesia. Moreover, the findings reveal a statistically significant positive correlation between obesity, high-risk food consumption, and lifestyle risk factors with the prevalence of several NCDs, including diabetes mellitus, heart disease, hypertension, and chronic kidney disease. These results underscore the potential impact of our research on public health in Indonesia. The results highlight also the urgent need for targeted public health initiatives, such as policies promoting healthier food choices, controlling the food environment, encouraging physical activity, and supporting smoking cessation to mitigate the growing burden of NCDs in Indonesia.


Analysis Of Differentially Expressed Genes (Deg) And Upstream Regulator Proteins Indicates That Inhibition Of Transforming Growth Factor Beta 1 (Tgfb1) Is A Potential Target For Acne Inversa, Weri Veranita, Siva Fauziah, Siti Nurbaya Apr 2025

Analysis Of Differentially Expressed Genes (Deg) And Upstream Regulator Proteins Indicates That Inhibition Of Transforming Growth Factor Beta 1 (Tgfb1) Is A Potential Target For Acne Inversa, Weri Veranita, Siva Fauziah, Siti Nurbaya

Indonesian Journal of Medical Chemistry and Bioinformatics

Acne inversa (AI) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and scarring, primarily in intertriginous areas. This study aims to identify potential therapeutic targets for managing acne inversa based on the analysis of differentially expressed genes (DEG). The expression targets of these genes were then validated for their potential as biomarkers, and upstream regulator proteins (URPs) were identified from the resulting DEG. DEG analysis on the GEO dataset GSE122592 (acne inversa vs. healthy donor skin) revealed five DEG that can serve as biomarkers for acne inversa, with a sensitivity and specificity of (100%). These DEG—IL10, GZMB, …


Phytochemistry, Antioxidant And Cytotoxic Activities Of Hibiscus (Hibiscus Rosa-Sinensis) Extract On Mcf-7 Breast Cancer Cells, Ade Arsianti, Isma Zahira Suhaima, Steven Gill, Ajeng Megawati Fajrin, Lince Dameria Nadapdap, Norma Nur Azizah, Hiroki Tanimoto, Shun Hirota Apr 2025

Phytochemistry, Antioxidant And Cytotoxic Activities Of Hibiscus (Hibiscus Rosa-Sinensis) Extract On Mcf-7 Breast Cancer Cells, Ade Arsianti, Isma Zahira Suhaima, Steven Gill, Ajeng Megawati Fajrin, Lince Dameria Nadapdap, Norma Nur Azizah, Hiroki Tanimoto, Shun Hirota

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: Breast cancer is the most common type of cancer in women with a very high mortality rate. This cancer is caused by uncontrolled growth of breast cells. Treatments for this malignancy are surgery, chemotherapy, and radiotherapy, however those methods can cause adverse effects and quite expensive. Complementary and alternative medicines (CAMs) are also used to support those main treatments, one of them is herbal medicine. Hibiscus rosa-sinensis is known to have various phytochemical components with antioxidant, antibacterial, anticancer, and analgesic activities. This study is aimed to determine the phytochemical composition, antioxidant activity and cytotoxicity of Hibiscus rosa-sinensis extract towards …


Protecting Female Workers Amidst The Controversy Of Cheap Labor Market: A Comparative Advantage Analysis In Southeast Asia, Dita Nur Safitri Apr 2025

Protecting Female Workers Amidst The Controversy Of Cheap Labor Market: A Comparative Advantage Analysis In Southeast Asia, Dita Nur Safitri

Jurnal Ilmu Kesejahteraan Sosial

In Southeast Asia, the cheap labor market is frequently mentioned as one of the comparative advantages that drive growth in the economy. However, this market frequently employs harmful labour practices against female workers. This study investigates the intersection of gender, labour practices, and economic advantages in the region, concentrating on the obstacles and protective measures for female workers. The key objective of this study is to examine how female workers are protected in Southeast Asia's low-wage labour markets, as well as to assess the effectiveness of these safeguards in preventing exploitation and improving working conditions. This study uses a comparative …


Hubungan Dukungan Sosial Rekan Kerja Dengan Stres Kerja (Studi Pada Pekerja Di Pt X), Aisyah Permatasari Apr 2025

Hubungan Dukungan Sosial Rekan Kerja Dengan Stres Kerja (Studi Pada Pekerja Di Pt X), Aisyah Permatasari

Jurnal Ilmu Kesejahteraan Sosial

Workers are vulnerable to work-related stress due to job demands, time constraints, and limited leisure time, leading to psychological issues such as anxiety related to their work. In the context of social welfare studies, job stress affects overall workers’ well-being and disrupts their social functioning in the workplace. Social support from coworkers is potentially reduce stress in workplace, which is crucial for creating organizational well-being. It also helps workers improve job engagement, cope with fatigue, and manage stress. This study examined the relationship between social support from coworkers and job stress among 90 employees …


Caring Across Borders: Demographic Shifts And Migrant Care In Asean-Korea Dynamics, Saqib Fardan Ahmada, Wahid Nur Kartiko Apr 2025

Caring Across Borders: Demographic Shifts And Migrant Care In Asean-Korea Dynamics, Saqib Fardan Ahmada, Wahid Nur Kartiko

Jurnal Ilmu Kesejahteraan Sosial

This article aims to examine the migration policies and migrant care in the context of relations between ASEAN Member States (AMS) and Korea. As Korea is dealing with an aging population, an increase in female labour force participation, and an ultra low fertility rate, caregiving, especially for the elderly, has become a pivotal issue. Besides, the traditional nuclear family structure, which has historically served as the primary caregiver for the elderly, is also losing its prominence. In such demographic shift, migrant care workers from AMS are filling the demand for caregiving in Korea, leading to a cross-border international migration from …


Profil Kadar Vitamin D Dan Hubungannya Dengan Derajat Keparahan Klinis Serta Parameter Inflamasi Pada Pasien Terkonfirmasi Covid-19, Wicensius Parulian Hasudungan, Andhika Rachman, Alvina Widhani, Arif Mansjoer Mar 2025

Profil Kadar Vitamin D Dan Hubungannya Dengan Derajat Keparahan Klinis Serta Parameter Inflamasi Pada Pasien Terkonfirmasi Covid-19, Wicensius Parulian Hasudungan, Andhika Rachman, Alvina Widhani, Arif Mansjoer

Jurnal Penyakit Dalam Indonesia

Introduction. The available data currently is not adequate to show the differences in vitamin D levels across various clinical stages of COVID-19 in Indonesia. Therefore, this study was conducted to determine the profile of vitamin D levels and its relationship with the clinical severity and inflammatory parameters in confirmed COVID-19 patients.

Methods. The study was conducted at Cipto Mangunkusumo Hospital and Wisma Atlet COVID-19 Emergency Hospital from January to December 2021. Subjects who were 18 years old and above and had confirmed COVID-19 status through COVID-19 Polymerase Chain Reaction (PCR) from oropharyngeal swab were included. Those who refused …


Profil Anafilaksis Di Rsu Hasanah Graha Afiah, Depok Pada Januari 2023 – April 2024, Sukamto Koesnoe, Risky Wulandari, Bramantya Wicaksana Mar 2025

Profil Anafilaksis Di Rsu Hasanah Graha Afiah, Depok Pada Januari 2023 – April 2024, Sukamto Koesnoe, Risky Wulandari, Bramantya Wicaksana

Jurnal Penyakit Dalam Indonesia

Introduction. Anaphylaxis is a severe hypersensitivity reaction that occurs rapidly and can be life-threatening. This reaction disrupts the respiratory, cardiovascular, digestive, and/or integumentary systems. The global prevalence of anaphylaxis is 1-2%, with a mortality rate of 0.3%. However, data on anaphylaxis in Indonesia is very limited. The aim of this study was to obtain anaphylaxis profile at Hasanah Graha Afiah Hospital, Depok.

Methods. This study used a cross-sectional descriptive study from January 2023 to April 2024 at Hasanah Graha Afiah Hospital, Depok, Jawa Barat. Inclusion criteria include patients aged ≥17 years, diagnosed with anaphylaxis in medical records in …


Hubungan Heart Rate Variability Dengan Global Longitudinal Strain Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Jakarta, Dwi Rendra Hadi, Lusiani Rusdi, Tri Juli Edi Tarigan, Arif Mansjoer Mar 2025

Hubungan Heart Rate Variability Dengan Global Longitudinal Strain Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Jakarta, Dwi Rendra Hadi, Lusiani Rusdi, Tri Juli Edi Tarigan, Arif Mansjoer

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetes mellitus (DM) remains a major global health issue due to its direct consequences and complications, particularly cardiovascular complications. These complications are influenced by autonomic neuropathy, which can be assessed by Heart Rate Variability (HRV). Autonomic dysfunction is thought to impair heart function, which can potentially be predicted early by observing Global Longitudinal Strain (GLS). The relationship between HRV and GLS has not been extensively studied. Therefore, this study aimed to identify the relationship between HRV and GLS.

Methods. A cross-sectional study with a population of adult type 2 DM patients residing in Jakarta in December 2020. …


Infeksi Oportunistik Pada Pasien Hiv Yang Dirawat Inap Di Rsup Dr. Hasan Sadikin Bandung Tahun 2019-2022, Katarina Salma, Yovita Hartantri, Nisa Fauziah Mar 2025

Infeksi Oportunistik Pada Pasien Hiv Yang Dirawat Inap Di Rsup Dr. Hasan Sadikin Bandung Tahun 2019-2022, Katarina Salma, Yovita Hartantri, Nisa Fauziah

Jurnal Penyakit Dalam Indonesia

Introduction. Human Immunodeficiency Virus (HIV) is a virus that infects and attacks the human immune system. The high morbidity and mortality rates in HIV patients can be attributed to various factors, one of which is the presence of opportunistic infections due to the weakened immune response, making HIV patients highly susceptible to other infections. This study aims to provide an overview of opportunistic infections in HIV patients hospitalized at Dr. Hasan Sadikin General Hospital in Bandung within the period of 2019-2022.

Methods. This descriptive observational study was conducted on 255 HIV patients with opportunistic infections who were hospitalized at dr. …