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Articles 7081 - 7110 of 8080
Full-Text Articles in Medicine and Health Sciences
Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen
Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen
Turkish Journal of Medical Sciences
The expression of major histocompatibility antigens class II (MHC II) in renal diseases has been studied extensively in the tubulo-interstitial compartment, while there are few articles about their expression in the glomeruli. In this series, glomerular expression of HLA DR DP DQ is evaluated in a total of 62 cases of pyelonephritis, glomerulonephritis, tubulointerstitial nephritis and systemic diseases with renal manifestations in order to identify their relationship with disease status and renal scarring. Formaline fixed paraffin embedded tissue sections from renal biopsy and nefrectomy specimens were stained by an antibody against HLA DR DP DQ by the streptavidin biotin method. …
Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley
Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley
Turkish Journal of Medical Sciences
Absorption of zinc by preterm infants from a synthetic milk labelled extrinsically with 70Zn tracer was determined by faecal monitoring. Six male preterm babies with a mean gestational age of 31±2.9 weeks and a mean birth weight of 1.23±0.24 kg were studied for three balance periods of 72 h with intervals ranging from 6 to 30 days. The babies were fed with the milk containing zinc with added 70Zn tracer. The net (NA) and true (TA) absorption, and endogenous loss (EL) of zinc were determined by the classical (chemical) balance and isotopic approaches. The mean TA, NA and EL were …
A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti
A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti
Turkish Journal of Medical Sciences
Chronic inflammatory gingival enlargement (CIGE) occasionally exhibits some similarities with hemangioma (Hm) by means of the clinical and histopathological features of gingiva. When compared with hemangioma, CIGE is more frequently encountered by the dental profession. However, Hm is rarely seen on gingiva and it has a non-inflammatory nature and mostly congenital origin. The present paper reports the clinic and histopathologic features of CIGE and Hm of gingiva in patients referred to our clinic suffering primarily from gingival overgrowth. Twenty-one patients were diagnosed as having CIGE (in a 4-month period) and 10 patients were diagnosed as having Hm (in a 12-month …
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu
Turkish Journal of Medical Sciences
The cortical thickness of the mandible (CTM) and its bone mineral density may be affected by tooth extraction. There is little knowledge of how the number of teeth in the mandible affect the cortical thickness and bone mineral density of the mandible in 2 different parts. The purpose of this study was to demonstrate whether there is any relationship between the number of teeth extracted and the cortical thickness and bone mineral density of the mandible. A total of 64 cases were evaluated in this study. The patients were divided into four groups. Group 1 consisted of 24 patients who …
A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay
A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay
Turkish Journal of Medical Sciences
No abstract provided.
The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar
The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar
Turkish Journal of Medical Sciences
No abstract provided.
Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan
Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan
Turkish Journal of Medical Sciences
From prokaryotes to eukaryotes or from invertebrates to vertebrates, all organisms have developed various adaptive mechanisms to survive within a wide range of growth temperatures. An important part of the cold adaptation mechanism occurs at the level of the cytoplasmic membrane. Cold shock affects the membrane composition and organisation to maintain the optimum membrane function. Cold shock also affects cell division. The temperature downshift results in a growth lag. During the lag phase the organism changes the composition of the cytoplasmic membrane and synthesis sets of specific proteins called cold shock proteins or cold induced proteins.
Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin
Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin
Turkish Journal of Medical Sciences
Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the bacterial population of intestinal lumen and on bacterial translocation in acute pancreatitis. Materials and Methods: Forty Sprague-Dawley adult male rats were divided into 4 groups. Experimental pancreatitis was induced by ligating the main biliopancreatic duct. All groups were given the standard rat diet and tap water. In addition, Group II was given. 15 mg/kg/day of L-glutamine via a catheter enterally, Group III was given 3 ml of laxative via a catheter enterally, and Group IV was given 3 IU/kg/day of NPH insulin via a catheter enterally. The …
The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay
The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay
Turkish Journal of Medical Sciences
Corticosteroids, widely used in the treatment of collagen tissue diseases, increase the number of neutrophils and decrease the total numbers of lymphocytes, monocytes, eosinophils and basophils. In addition, corticosteroids alter important functional activities of both lymphocytes and monocytes. They suppress the bactericidial activities of phagocytes. In this manner, the resistance to infections is reduced. Cytotoxic drugs can have profound effects on the production and function of both phagocyte cells and lymphocytes. We followed up 115 patients with collagen tissue disease for two years and 22 of them had infections. Eight of these 22 patients had urinary tract infection, six had …
Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir
Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir
Turkish Journal of Medical Sciences
Caudate hemorrhage is a rare stroke syndrome that accounts for only 3-7% of all primary intracerebral hematomas. In this study, we evaluated eight patients with isolated caudate nucleus hemorrhage for their clinical presentation and neurological findings. Material and methods: Eight patients, who were admitted to our department with isolated caudate nucleus hemorrhage, were evaluated for their clinical presentation and present risk factor findings on neurological examination and prognosis. Results: The most common symptoms on admission were headache and vomiting (five patients), whereas the most common findings on neurological examination were unconsciousness and neck stiffness (four patients). Two patients who were …
The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r
The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r
Turkish Journal of Medical Sciences
Cast alloys used in dentistry come into close and prolonged contact with the gingiva and the oral mucosa, and certain alloys have been claimed to cause inflammation of gingival and periodontal tissues. However, only little information is available on the molecules mediating the mechanism of such an effect. For this reason, the aims of this study were to determine 1L-1\beta levels in the gingival crevicular fluid (GCF) before and after the placement of base, high-noble metal-ceramic and all-ceramic crowns. Thirty patients requiring an artificial crown for a maxillary second premolar were suitable for the present study; 18 were male and …
A Rare Cause Of Upper Gastrointestinal System Bleeding: Pancreatic Endocrine Neoplasm, Oral Saygun, Fati̇h Mehmet Avşar, İ. Hakan Özel, Süleyman Hengi̇rmen, Levent Albayrak, Sema Hücümenoğlu
A Rare Cause Of Upper Gastrointestinal System Bleeding: Pancreatic Endocrine Neoplasm, Oral Saygun, Fati̇h Mehmet Avşar, İ. Hakan Özel, Süleyman Hengi̇rmen, Levent Albayrak, Sema Hücümenoğlu
Turkish Journal of Medical Sciences
No abstract provided.
Lateral Periodontal Cyst, Işil Saygun, Ati̇lla Özdemi̇r, Mükerrem Safali
Lateral Periodontal Cyst, Işil Saygun, Ati̇lla Özdemi̇r, Mükerrem Safali
Turkish Journal of Medical Sciences
No abstract provided.
Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇
Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇
Turkish Journal of Medical Sciences
The aim of this study is to investigate the effects of PAF antagonist BN52021 on systemic and renal oxidative stress in experimentally induced obstructive jaundice. A total of 30 Wistar-Albino type rats used in the study were divided into sham, control and study groups, each consisting of ten subjects. A laparotomy was performed on the study and control groups, and the choledochus was ligated and dissected. In the sham group, the choledochus was dissected by laparotomy and not ligated. The subjects in the control group were administered physiological saline intraperiotoneally between the 2^{nd} and 7^{th} days, and subjects in the …
The Effects Of Different Suture Techniques On Wound Healing In Abdominal Wall Closure, Mustafa Şahi̇n, Mehmet Karademi̇r, Şükrü Özer, Fati̇h Mehmet Avşar, Serdar Yol, Osman Çağlayan, Murat Aktan
The Effects Of Different Suture Techniques On Wound Healing In Abdominal Wall Closure, Mustafa Şahi̇n, Mehmet Karademi̇r, Şükrü Özer, Fati̇h Mehmet Avşar, Serdar Yol, Osman Çağlayan, Murat Aktan
Turkish Journal of Medical Sciences
Purpose: The aim this study was to investigate the effects of different suture techniques on the healing of abdominal wall wound. Materials and Methods: 24 male Wistar albino rats were included in this study. The rats were divided into two groups. A 4 cm midline laparatomy was performed after ketamine HCl anesthesia. In Group I, the incision was sutured with 4/0 polypropylene interruptedly and in Group II, the wound was closed with 4/0 polypropylene continuously. The skin was sutured with an interrupted 4/0 silk suture. Then 2 cc of blood was withdrawn for biochemical and hematological tests by cardiac puncture. …
Comparative Histological Analysis Of Hepatitis C Virus With Hepatitis B, Gülen Akyol, Özlem Süer, Cem Sezer
Comparative Histological Analysis Of Hepatitis C Virus With Hepatitis B, Gülen Akyol, Özlem Süer, Cem Sezer
Turkish Journal of Medical Sciences
Aims: Rates of certain histopathologic features were evaluated in hepatitis C and in hepatitis B materials and analyzed statistically in a Turkish population. Method: The presence of lymphoid aggregate, steatosis, ductal lesions, sinusoidal inflammation and portal iron deposition were investigated in 80 hepatitis C and 104 hepatitis B specimens and evaluated using the chi-square test and Fisher's exact test. Pan Band T cell markers were used for lymphoid aggregate analysis. P53 and PCNA were applied for the possible impact of steatosis on cell biology. Results: All mentioned parameters excluding sinusoidal inflammation were found to be higher in hepatitis C samples. …
Allele Frequencıes Of The Humf13b Str Locus In The Çukurova Region, Lale Dönbak, Serpi̇l Salaçi̇n
Allele Frequencıes Of The Humf13b Str Locus In The Çukurova Region, Lale Dönbak, Serpi̇l Salaçi̇n
Turkish Journal of Medical Sciences
In this study, the STR system HumF13B polymorphism and forensic efficiency values were investigated in a population sample from the Çukurova region. The F13B phenotypes were analysed using polyacrylamide gel electrophoresis (PAGE) following a polymerase chain reaction (PCR) and were visualised by silver staining. Allele frequencies were calculated by the gene counting method. Forensic efficiency values were estimated using the obtained gene frequencies of F13B. In this population sample, a total of five alleles, 6, 7, 8, 9 and 10 of F13B, were observed. The calculated frequencies of these alleles were as follows: 6=0.0910; 7=0.0045; 8=0.3273; 9=0.2045; 10=0.3727. In the …
Medicolegal Aspects Of Blood-Urine Toluene And Urinary Ortho-Cresol Concentrations In Toluene Exposure, Serap A. Akgür, Pembe Öztürk, Yusuf Kurtulmuş, Hüseyi̇n Karali̇, Süheyla Ertürk
Medicolegal Aspects Of Blood-Urine Toluene And Urinary Ortho-Cresol Concentrations In Toluene Exposure, Serap A. Akgür, Pembe Öztürk, Yusuf Kurtulmuş, Hüseyi̇n Karali̇, Süheyla Ertürk
Turkish Journal of Medical Sciences
Toluene is a widely used solvent in different industrial areas and has a depressant effect on the central nervous system. In medicolegal cases, for the possible influence of toluene on actions or conditions prior to death, a reliable indicator of exposure must be precisely investigated. We developed an appropriate method for toluene analysis and investigate the blood-urine toluene levels and urinary ortho-cresol levels in toluene-exposed workers. Blood and urine toluene levels from 50 male subjects were detected by Gas Chromatography-FID (GC-FID) using the head-space method, and urinary o-cresol levels, a metabolite of toluene, were analyzed by GC. The significance of …
Thalamic Hemorrhage (Presentation And Prognosis Of Hemorrhages), Şule Bi̇len, Selçuk Çomoğlu, Yaşar Şahi̇n, Şenay Özbakir
Thalamic Hemorrhage (Presentation And Prognosis Of Hemorrhages), Şule Bi̇len, Selçuk Çomoğlu, Yaşar Şahi̇n, Şenay Özbakir
Turkish Journal of Medical Sciences
The thalamus is one of the most vulnerable areas for intracerebral hemorrhages. In this study, we investigated the parameters of thalamic hemorrhage such as risk factors, initial complaints, neurologic findings and the prognostic effects of the presence or absence of ventricular penetration, as well as the volume and size of hematoma. A total of 57 patients with thalamic hemorrhage, whose diagnosis was confirmed by cranial computerized tomography, were evaluated. The most significant risk factor was hypertension, while the most common initial clinic symptom was incontinence. Those patients who had small hemorrhagic size of low volume and the presence of ventricular …
Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk
Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk
Turkish Journal of Medical Sciences
A prospective, observational study was carried out to assess the efficacy of Large Loop Excision of the Transformation Zone (LLETZ) as an outpatient procedure during the first visit of patients with abnormal cervical smears. One hundred and seven women were treated with LLETZ under local anaesthesia as an outpatient procedure at their first visit. All patients were followed up routinely with colposcopy, cytology, and also histology where appropriate for at least 6 months. In all cases, the specimens obtained were adequate for histopathological assessment, and in 103 cases (96%), the lesion had been completely excised. When compared, the degree of …
Serum Triglyceride And Lipoprotein-Cholesterol Levels In Patients With And Without Luteal Phase Defect, Hi̇kmet Hassa, Ömer T. Yalçin, Atti̇la Yildirim, H. Mete Tanir, Özgül Paşaoğlu, Mi̇ne İnan
Serum Triglyceride And Lipoprotein-Cholesterol Levels In Patients With And Without Luteal Phase Defect, Hi̇kmet Hassa, Ömer T. Yalçin, Atti̇la Yildirim, H. Mete Tanir, Özgül Paşaoğlu, Mi̇ne İnan
Turkish Journal of Medical Sciences
Objective: To evaluate the serum triglyceride and lipoprotein-cholesterol levels in subjects with and without luteal phase defect. Method: Early follicular and midluteal phase serum triglycerides, lipoprotein-cholesterol and progesterone levels were assessed in 19 subjects with and in 73 subjects without luteal phase defect. The criterion for diagnosis of luteal phase defect was histological development of endometrium delayed for more than 2 days according to the chronological day. The data were analyzed by paired and unpaired t tests, Chi-square test and correlation analysis. Results: The early follicular serum triglyceride and lipoprotein-cholesterol levels of the two groups were similar (p>0.05). The …
Frequency Of Use Of The Various Classes Of Removable Partial Dentures And Selection Of Major Connectors And Direct / Indirect Retainers, Fi̇li̇z Keyf
Turkish Journal of Medical Sciences
Selecting the individually suitable form of and location for the major connectors in partially edentulous patients is important. The purpose of classifying removable partial dentures (RPDs) is to simplify identification. Classification also allows for a longitudinal comparison of various classes of RPDs as well as the determination of whether the teaching of RPD design is consistent with the relative frequencies of RPD use. This study surveyed the various types of RPDs being fabricated in a dental laboratory and compared those findings with the data from a previous study. Results indicated that mandibular RPDs are more common than maxillary RPDs, and …
Paget's Disease Of The Male Breast - A Case Report, Sema Hücümenoğlu, Handan Kaya, Fati̇h Mehmet Avşar
Paget's Disease Of The Male Breast - A Case Report, Sema Hücümenoğlu, Handan Kaya, Fati̇h Mehmet Avşar
Turkish Journal of Medical Sciences
ÜMENOĞLU^1 Handan KAYA^2 Fatih Mehmet AVŞAR^3 ^1Department of Pathology, SSK Ankara Training and Research Hospital, Ankara, ^2Department of Pathology, Faculty of Medicine, Marmara University, Istanbul, ^3Department of 1st Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY
A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n
A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n
Turkish Journal of Medical Sciences
SÜNGÜ^1 Birsen KARAMAN^2 E. Ferda PERÇİN^1 Sevim BALCI^3 İlhan SEZGİN^1 ^1Department of Medical Biology and Genetics, Faculty of Medicine, Cumhuriyet University 58140-Sivas, ^2Department of Medical Genetics, Faculty of Medicine, Istanbul University, Çapa -Istanbul, ^3Department of Pediatrics, Faculty of Medicine, Hacettepe University Ankara - TURKEY
Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal
Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal
Turkish Journal of Medical Sciences
Nitric oxide (NO) is a colorless gas with high affinity to ferrous hemoproteins. This simple molecule is a powerful messenger in the body. This study reviews a literature search using keywords and abstracts in English through Medline. Recent advances in the therapeutic uses of inhaled nitric oxide in lung diseases and other pathologic states urges the efficient and convenient use of nitric oxide in hospital practice. In addition, methods of inhaled nitric oxide delivery, chemiluminescence and electrochemical analyzers were reviewed. The performance characteristics of different equipment were compared. The novel methods of nitric oxide measurements that utilize simple and cheaper …
Colicin Production And Colicin Typing Of Uropathogenic Escherichia Coli, Ayli̇n İmren Çarikçi, Güner Coşar
Colicin Production And Colicin Typing Of Uropathogenic Escherichia Coli, Ayli̇n İmren Çarikçi, Güner Coşar
Turkish Journal of Medical Sciences
Colicins are bactericidal macromolecules in protein structures and they are produced by some strains of Escherichia coli and Shigella, which are members of the Enterobacteriaceae. They have a bactericidal effect on the same species or closely related bacteria, but have no effect on the strains which produce them. In this study, 129 E. coli strains isolated from urine samples of patients in Izmir and Manisa were examined for colicin production, and the colicinogenic strains were examined for their colicin types by means of Horak specific indicator strains. Indicator strains were obtained from the National Type Culture Collection Hygiene and Epidemiology …
Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary
Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary
Turkish Journal of Medical Sciences
Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.
Human Herpesvirus 8 (Hhv-8) In Non-Hiv Associated Forms Of Kaposi's Sarcoma From Turkey, Ni̇lgün Şentürk, Sedef Şahi̇n, Serpi̇l Erci̇ş, Tanil Kocagöz, Ni̇lgün Atakan
Human Herpesvirus 8 (Hhv-8) In Non-Hiv Associated Forms Of Kaposi's Sarcoma From Turkey, Ni̇lgün Şentürk, Sedef Şahi̇n, Serpi̇l Erci̇ş, Tanil Kocagöz, Ni̇lgün Atakan
Turkish Journal of Medical Sciences
Objective: Kaposi's sarcoma (KS), first described in 1872 by Moritz Kaposi, is a spindle cell, multifocal vascular tumor. Despite the intense work on the pathogenesis of KS, its etiology remains in doubt. The aim of this study was to determine the presence of HHV-8 sequences in non-HIV associated Kaposi's sarcoma patients, namely classical and immunosuppression-associated, and compare the results with normal healthy subjects. Materials and Methods: Nineteen patients with classical Kaposi's sarcoma (CKS), and nine patients with immunosuppression-associated Kaposi's sarcoma (ISKS) (6 renal transplantation, 1 Behçet's disease, 1 high grade lymphoma, 1 ataxia telangiectasia) were included in this study. Skin …
Detection Of Human Papilloma Virus In Benign, Malignant And Pre-Cancerous Lesions Of Oral Mucosa By In Situ Hybridization, Mehmet Yaltirik, Ayla Özveren, Canan Alatli, Nevi̇n Büyükakyüz
Detection Of Human Papilloma Virus In Benign, Malignant And Pre-Cancerous Lesions Of Oral Mucosa By In Situ Hybridization, Mehmet Yaltirik, Ayla Özveren, Canan Alatli, Nevi̇n Büyükakyüz
Turkish Journal of Medical Sciences
HPV is an epitheliotropic virus, predominantly associated with human skin and mucosal lesions. In many studies, the presence of HPV types 6/11, 16/18 and 31/33/51 have been demonstrated in oral lesions. The aim of this study is to investigate the presence of specific types of HPV in oral benign and precancerous epithelial lesions and oral carcinomas, and the etiological significance of HPV in oral epithelial malignancies. In the present study, twenty oral lesions, of which seven were papilloma, seven squamous cell carcinoma, four leukoplakia and two lichen planus, were tested for different types of HPV. In addition, these patients were …
Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer
Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer
Turkish Journal of Medical Sciences
The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a group of patients with chronic hepatitis B at various stages of the disease. Four liver biopsy specimens taken from the patients with chronic hepatitis B infection and five control liver tissue specimens with normal histology were studied. Liver specimens were scored for disease severity according to Knodell's hepatic activity index (HAI). The percentage of hepatic expression was evaluated semi-quantitively. Our immunohistochemical study showed that …