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Articles 4651 - 4680 of 8080
Full-Text Articles in Medicine and Health Sciences
Contribution Of Phospholipase C And Protein Kinase C But Not Endothelin-Converting Enzyme To Contractile Responses Of Ethanol, Naci̇ye Döndaş, Hali̇l Mahi̇r Kaplan, Derya Kaya, Erği̇n Şi̇ngi̇ri̇k
Contribution Of Phospholipase C And Protein Kinase C But Not Endothelin-Converting Enzyme To Contractile Responses Of Ethanol, Naci̇ye Döndaş, Hali̇l Mahi̇r Kaplan, Derya Kaya, Erği̇n Şi̇ngi̇ri̇k
Turkish Journal of Medical Sciences
Aim: To evaluate the possible roles of phospholipase C, protein kinase C, and endothelin-converting enzyme on contractions induced by ethanol (164 mM) in isolated gastric fundal strips of mice. Materials and methods: After the mice were killed, the stomach of each was removed and longitudinal muscle strips were prepared from the gastric fundus. The strips were mounted in organ baths and their responses were recorded isometrically. Ethanol (164 mM) was added to the organ baths and a steady-state contraction was obtained. After the first ethanol response was recorded, the preparations were incubated separately with lidocaine (1-100 µM), neomycin (10-500 µM), …
The Effects Of The Cobra Perilaryngeal Airway On Intraocular Pressure, Lale Karabiyik, Sema Öncül, Gökçen Emmez
The Effects Of The Cobra Perilaryngeal Airway On Intraocular Pressure, Lale Karabiyik, Sema Öncül, Gökçen Emmez
Turkish Journal of Medical Sciences
Aim: To compare the effects of the Cobra perilaryngeal airway on intraocular pressure with the effects of the classic laryngeal mask and endotracheal intubation. Materials and methods: Forty-five ASA I or II patients were randomly allocated into 3 equal groups. Endotracheal intubation (EI group), the classic laryngeal mask airway (cLMA group), and the Cobra perilaryngeal airway (Cobra PLA group) were applied to the groups. Heart rate and systolic, diastolic, and mean arterial pressures were recorded. Intraocular pressure was measured with an applanation tonometer before and during the 15 min after application. Results: Heart rate and systolic, diastolic, and mean arterial …
The Effect Of N-Acetylcysteine On Growth And Biofilm Formation In Staphylococcus Epidermidis Strains, Sahra Kirmusaoğlu, Seyhun Yurdugül, Mücahi̇de Esra Koçoğlu
The Effect Of N-Acetylcysteine On Growth And Biofilm Formation In Staphylococcus Epidermidis Strains, Sahra Kirmusaoğlu, Seyhun Yurdugül, Mücahi̇de Esra Koçoğlu
Turkish Journal of Medical Sciences
Aim: To examine the possible preventive effect of N-acetylcysteine (NAC) on biofilm formation in Staphylococcus epidermidis strains, which cause very important problems such as implant-associated infections in hospitalized and immunocompromised patients worldwide. Materials and methods: The effects of varying concentrations of NAC on the formation of biofilm by 28 strains of Staphylococcus epidermidis was investigated spectrophotometrically by micro-ELISA assay. Results: Significant differences in biofilm formation in the presence of various NAC concentrations were found in 15 methicillin-resistant Staphylococcus epidermidis and 13 methicillin-sensitive Staphylococcus epidermidis strains (P < 0.05). Conclusion: It was found that slime formation was decreased due to the increased concentrations of the NAC treatments. Based on these findings, it is possible to use NAC as an antibiofilm agent on medical devices or in catheter lock solutions to prevent colonization and implant-associated infections.
In Vitro Efficacy Of Hyperbaric Oxygen Therapy Against Leishmania Tropica Promastigotes And Amastigotes, Özgür Koru, Soykan Özkoç, Kemal Şi̇mşek, Gürkan Mert, Hakan Ay, Seray Töz, Mehmet Tanyüksel
In Vitro Efficacy Of Hyperbaric Oxygen Therapy Against Leishmania Tropica Promastigotes And Amastigotes, Özgür Koru, Soykan Özkoç, Kemal Şi̇mşek, Gürkan Mert, Hakan Ay, Seray Töz, Mehmet Tanyüksel
Turkish Journal of Medical Sciences
Aim: To assess the efficiency of hyperbaric oxygen (HBO) therapy on L. tropica, which is the major causative agent of cutaneous leishmaniasis in Turkey. Materials and methods: The effects of HBO on Leishmania tropica promastigote and amastigote forms were studied at a pressure of 2.5 atmosphere absolute (ata). We examined the cytotoxic effect of HBO on promastigotes using the trypan blue exclusion test and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye-reduction assay. To investigate the effects of HBO treatment on the growth of the promastigotes, HBO-treated and non-HBO-treated cell culture flasks were incubated at 26 °C for 3 days, while the effects …
Cortical And Medullary Vascularity In Renal Allograft Biopsies, Şadi̇ye Mehtat Ünlü, Ali̇ Çeli̇k, Funda Sağlam Eyi̇ler, Si̇bel Ersan, Sülen Sarioğlu
Cortical And Medullary Vascularity In Renal Allograft Biopsies, Şadi̇ye Mehtat Ünlü, Ali̇ Çeli̇k, Funda Sağlam Eyi̇ler, Si̇bel Ersan, Sülen Sarioğlu
Turkish Journal of Medical Sciences
Aim: To evaluate the relation between cortical and medullary peritubular capillaries (PTCs) and scarring. There are presently no studies about medullary PTCs in renal allograft biopsies. Materials and methods: Nonprotocol allograft biopsies were evaluated and 41 with adequate medullary and cortical tissues were selected. Vascular structures were counted separately at the medulla and cortex on anti-CD34 stained sections. Other histopathological and clinical findings were retrieved from the patient files. Results: A weak but positive correlation was found between the number of cortical vascular structures (nVC) and medullary vascular structures (nVM). The nVC and nVM were decreased in cases with increased …
Assessment Of Exposure To Tobacco Smoke: Measurement Of Exhaled Carbon Monoxide And Hair Nicotine, Sibel Doruk, İbrahi̇m Demi̇rtaş, Hüseyi̇n Akşi̇t, Ünal Erkorkmaz, Zehra Seyfi̇kli̇
Assessment Of Exposure To Tobacco Smoke: Measurement Of Exhaled Carbon Monoxide And Hair Nicotine, Sibel Doruk, İbrahi̇m Demi̇rtaş, Hüseyi̇n Akşi̇t, Ünal Erkorkmaz, Zehra Seyfi̇kli̇
Turkish Journal of Medical Sciences
Aim: To investigate the effect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monoxide (eCO) and hair nicotine (HN) and to evaluate the relationship between these values. Materials and methods: Included in the study were 96 subjects (64 male, 32 female) divided into 3 groups. The subjects in Group 1 (n = 46) were current smokers, and the subjects in Group 2 (n = 20) and Group 3 (n = 30) were nonsmokers with or without environmental TS exposure, respectively. The eCO level of all of the subjects was measured with a breath CO monitor. Gas chromatography/mass …
Transient Bradycardia In Patients With Crimean-Congo Hemorrhagic Fever, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden, Mehmet Parlak, Mustafa Kemal Erol
Transient Bradycardia In Patients With Crimean-Congo Hemorrhagic Fever, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden, Mehmet Parlak, Mustafa Kemal Erol
Turkish Journal of Medical Sciences
To determine the features and clinical course of bradycardia in patients with Crimean-Congo hemorrhagic fever (CCHF). Materials and methods: Between May 2002 and September 2010, a total of 380 patients with CCHF were followed. All patients who had transient bradycardia during this period were included in the study. Results: A total of 14 patients had an episode of bradycardia. All patients were in sinus rhythm. Three patients had clinical symptoms of bradycardia; atropine was administered to them. In the other patients, bradycardia resolved spontaneously. No patient had underlying conditions for bradycardia. Bradycardia appeared 7.0 ± 1.7 days after the first …
Effects Of Ankaferd Hemostat On The Synovial Fluid Of Patients With Osteoarthritis, Mehmet Aki̇f Öztürk, Zeli̇ha Koçak Tufan, Mehmet Derya Demi̇rağ, İbrahi̇m Celaletti̇n Haznedaroğlu
Effects Of Ankaferd Hemostat On The Synovial Fluid Of Patients With Osteoarthritis, Mehmet Aki̇f Öztürk, Zeli̇ha Koçak Tufan, Mehmet Derya Demi̇rağ, İbrahi̇m Celaletti̇n Haznedaroğlu
Turkish Journal of Medical Sciences
Ankaferd Blood Stopper (ABS) is a novel topical hemostatic agent with antiinfective, wound healing, and antineoplastic properties. In this study, we evaluated the macroscopic and biochemical effects of ABS in the joint fluid of patients with osteoarthritis. Materials and methods: Synovial fluid samples were obtained from 10 patients with osteoarthritis (5 women, 5 men; mean age 57.6 ± 11.2 years). From each patient, 4 mL of synovial fluid was drawn and put into 2 different serum separator tubes, and 1 mL of ABS was added to the first sample and 1 mL of 0.9% saline was added to the second …
Btla (C272) Expression On Cd4+ T Cells In Behçet Patients, Nafi̇ye Fulya İlhan, Nesri̇n Demi̇r, Tamer Demi̇r, Ahmet Gödekmerdan
Btla (C272) Expression On Cd4+ T Cells In Behçet Patients, Nafi̇ye Fulya İlhan, Nesri̇n Demi̇r, Tamer Demi̇r, Ahmet Gödekmerdan
Turkish Journal of Medical Sciences
To investigate the peripheral blood levels of B and T lymphocyte attenuator (BTLA/CD272) on T cells and its role in Behçet disease (BD), and to define the role of inhibitory receptors on BD. Materials and methods: Included in this study were 25 patients with BD and 20 healthy control subjects, matched for age and sex. Results: CD4+CD272+ (P < 0.001) and CD3+CD272+ (P < 0.001) T cell levels were significantly higher in BD patients (active and remission) compared to the healthy controls. However, there was no difference between the active patients and those in remission in terms of CD4+CD272+ T cells, while CD3+CD272+ T cell levels were significantly higher in active-phase BD patients compared to patients in the remission phase (P < 0.05). Conclusion: Further functional studies could be implemented to investigate the effectiveness of the present research parameter in the diagnosis or follow-up of certain diseases similar to BD and with obscure etiology, as well as its contribution to immune dysregulation of BD. BTLA can additionally modulate T cell response in BD on different inflammatory areas and it can be upregulated in BD because of T cell activation. The results of the present study indicate that BTLA expression on CD4+ Th (T helper) cells might play a limiting role on the inflammation at peripheral sites or organs in BD.
Chest Radiography And Computed Tomography Findings Of Cases With Pandemic Influenza A (H1n1/09) Infection, Pinar Nerci̇s Koşar, Zeli̇ha Koçak Tufan, Eli̇f Ergün, Hasan Yi̇ği̇t, Uğur Koşar, Ali̇ Pekcan Demi̇röz
Chest Radiography And Computed Tomography Findings Of Cases With Pandemic Influenza A (H1n1/09) Infection, Pinar Nerci̇s Koşar, Zeli̇ha Koçak Tufan, Eli̇f Ergün, Hasan Yi̇ği̇t, Uğur Koşar, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
To review the radiological findings of the chests of swine flu patients whose infections were confirmed clinically and/or by laboratory tests. Materials and methods: This study was conducted in the radiology and infectious diseases departments of a tertiary care hospital, Ankara Training and Research Hospital, Ankara, Turkey. The X-ray and thorax computed tomography (CT) findings of swine flu patients were evaluated. Results: Included were 53 cases of swine flu. Thirty-eight of the patients (72%) underwent an initial chest X-ray and 17 (32%) underwent thorax CT examinations. The mean age of the patients was 41 years; 23 (43%) patients were male …
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Turkish Journal of Medical Sciences
To evaluate the effects of diabetes on nitric oxide synthase (NOS) activity and on gene expressions of B-cell lymphoma protein 2 (Bcl-2) and caspase-3 in the renal tissues of streptozotocin (STZ)-induced rats. Materials and methods: Twenty rats were analyzed in 2 equally distributed groups of healthy controls and STZ-induced diabetic rats. Rats with blood glucose levels of >=250 mg/dL were considered diabetic. Renal tissue sections were analyzed histomorphologically and immunohistochemically. Gene expressions of caspase-3 and Bcl-2 were evaluated by real-time quantitative polymerase chain reaction. Results: Bcl-2 expression significantly decreased in the diabetic group, both at the gene and protein level. …
The Effects Of Stress Urinary Incontinence On The Quality Of Life Of Turkish Women In The Reproductive Age Group, Elçi̇n Balci, Özlem Gürlevi̇k, İskender Gün, Osman Günay
The Effects Of Stress Urinary Incontinence On The Quality Of Life Of Turkish Women In The Reproductive Age Group, Elçi̇n Balci, Özlem Gürlevi̇k, İskender Gün, Osman Günay
Turkish Journal of Medical Sciences
This study was performed in order to evaluate the effect of urinary incontinence (UI) on the quality of life of women in the reproductive age group. Materials and methods: Included in the study were 150 women with UI [stress urinary incontinence (SUI) or mixed urinary incontinence (MUI)] and 150 healthy women, ranging in age between 15 and 49 years. Short Form 36 (SF-36) and the Urogenital Distress Inventory (UDI-6) were filled in by the women in both groups and the Incontinence Impact Questionnaire (IIQ-7) was filled in only by the women in the UI group. Unpaired t-tests and the general …
Clinical And Electrophysiological Evaluation Of Shoulder Functions In Spinal Accessory Nerve-Preserving Neck Dissection, Özgür Tarkan, Ülkü Tuncer, Hacer Bozdemi̇r, Tunay Sarpel, Süleyman Özdemi̇r, Özgür Sürmeli̇oğlu
Clinical And Electrophysiological Evaluation Of Shoulder Functions In Spinal Accessory Nerve-Preserving Neck Dissection, Özgür Tarkan, Ülkü Tuncer, Hacer Bozdemi̇r, Tunay Sarpel, Süleyman Özdemi̇r, Özgür Sürmeli̇oğlu
Turkish Journal of Medical Sciences
The aim of this study was to evaluate shoulder functions after neck dissection with preservation of the spinal accessory nerve by objective physical examination, electromyographic findings, and subjective patient complaints, and also to investigate the effect of the type of neck dissection. Materials and methods: The present study included 29 patients on whom unilateral selective or modified radical neck dissection was performed for head and neck cancer and/or metastasis to the neck. Electromyographical findings, range of motion, and pain scores of the shoulder joint were determined for the operated and nonoperated (control) sides. Results: An electromyographic examination of the trapezius …
Characteristics Of Patients Transferred By Air: A Descriptive Epidemiologic Study, Ataman Köse, Beri̇l Köse, Ayça Açikalin Akpinar, Özlem Köksal, Şule Aydin, Erol Armağan
Characteristics Of Patients Transferred By Air: A Descriptive Epidemiologic Study, Ataman Köse, Beri̇l Köse, Ayça Açikalin Akpinar, Özlem Köksal, Şule Aydin, Erol Armağan
Turkish Journal of Medical Sciences
To analyze the characteristics of patients transferred by air ambulance in the eastern Anatolia region of Turkey. Materials and methods: We retrospectively evaluated the records of patients transferred by air ambulance between January 2010 and December 2010. Demographics and medical data of the patients, geographic conditions, and flight duration data were all analyzed. Results: A total of 241 patients were included in the study, of whom 51% were men and 49% were women. The majority of the patients were between 0 and 1 year old (40.2%). In the adult patients, the most commonly seen diagnoses were trauma (31.6%), obstetric problems …
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Turkish Journal of Medical Sciences
We aim ed to predict mortality in stroke patients by using multilayer perceptron (MLP) neural networks. Materials and methods: A data set consisting of 584 stroke patients was analyzed using MLP neural networks. The effect of prognostic factors (age, hospitalization time, sex, hypertension, atrial fibrillation, embolism, stroke type, infection, diabetes mellitus, and ischemic heart disease) on mortality in stroke were trained with 6 different MLP algorithms [quick propagation (QP), Levenberg-Marquardt (LM), backpropagation (BP), quasi-Newton (QN), delta bar delta (DBD), and conjugate gradient descent (CGD)]. The performances of the MLP neural network algorithms were compared using the receiver operating characteristic (ROC) …
The Effects Of Stobadine On Purine Metabolism In Rats Treated With Carbon Tetrachloride, Ni̇lüfer Bayrakdar, Seda Duygulu Devay, Mi̇ne Yavuz Taşlipinar, Suna Ömeroğlu, Seyhan Gümüşlü, Mustafa Kavutçu, Orhan Canbolat
The Effects Of Stobadine On Purine Metabolism In Rats Treated With Carbon Tetrachloride, Ni̇lüfer Bayrakdar, Seda Duygulu Devay, Mi̇ne Yavuz Taşlipinar, Suna Ömeroğlu, Seyhan Gümüşlü, Mustafa Kavutçu, Orhan Canbolat
Turkish Journal of Medical Sciences
The aim of the present study was to investigate the relationship between liver damage induced by carbon tetrachloride (CCl_4) and adenosine deaminase (ADA), 5'-nucleotidase (5'NT), xanthine oxidase (XO) enzyme activities, and malondialdehyde (MDA) levels. The effect of stobadine on purine metabolism was also evaluated. Materials and methods: This study measured the effect of CCl_4 on ADA, 5'NT, XO enzyme activities, and MDA levels, and measured the histopathologic changes in liver cells. Results: Our research found that ADA, XO activities, and MDA levels increased in the CCl_4 group when compared with the control group. This was also supported by the histopathological …
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Turkish Journal of Medical Sciences
We aim ed to study the effect of a glutathione precursor, L-2-oxothiazolidine-4-carboxylic acid (OTCA), on the lung antioxidant defense system in an animal asthma model. Materials and methods: The study was carried out on 24 female C57BL/6 mice. The mice were divided into 4 treatment groups: group 1 - control group; group 2 - injected with ovalbumin (OVA) and given an OVA inhalant; group 3 - treated with OTCA and phosphate-buffered saline inhalant; and group 4 -injected with OVA and OTCA and given an OVA inhalant. Under sodium pentobarbital anesthesia the animals were killed by exsanguination 48 h after the …
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Turkish Journal of Medical Sciences
The purpose of this study was to evaluate cardiopulmonary responses of individuals with different fitness levels according to predetermined rating of perceived exertion (RPE) scores and to investigate the correspondence between the heart rate reserve percentage (HRR%) and the RPE scale by using fit and unfit subjects. Materials and methods: RPE scores of sedentary volunteers were recorded at different HRR% levels during graded exercise tests on a cycle ergometer. Following the tests, subjects were divided into 2 groups, high metabolic equivalent [(MET) MET >= 10; n = 9] and low MET (MET < 10; n = 11), according to maximal O_2 uptakes (VO_{2max}). Participants performed the steady-state exercise test at the 13th-14th level of their perceived exertion 48 h after the first test. Variance and regression analyses were performed. Results: For all HRR% values, RPE levels were not different between groups. During the graded exercise test, perceived exertion was significantly higher in the low MET group than in the high MET group. Predetermined RPE score results were significantly greater in the low MET group with relative O2 consumption as compared to the high MET group (P < 0.05-0.001). Conclusion: In individuals with different VO_{2max} levels, exercise intensity can be prescribed using HRR% or RPE scale methods while adjusting for individual differences in oxygen consumption.
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Turkish Journal of Medical Sciences
To investigate the electrophysiological findings of sciatic nerve injury following intramuscular injection and follow-up progression. Materials and methods: Included in the study were 26 patients (16 men, 10 women) with sciatic nerve injuries due to intramuscular injections who were admitted to our electrophysiology laboratory. The age, sex, and body mass index (BMI), along with the clinical and electrophysiological findings of each of the patients, were recorded. Tibial and peroneal nerve motor conduction studies, sural and superficial peroneal nerve sensorial conduction studies, and needle electromyography were performed. The patients were reevaluated for electrophysiological evaluation at 3 and 6 months and 1 …
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Turkish Journal of Medical Sciences
To determine the effect of limb remote ischemic postconditioning (LIPoC) against cerebral ischemia reperfusion in rats and the relationship between cycle number or remote postconditioning episode duration and the protective function of LIPoC. Materials and methods: Transient focal ischemia/reperfusion was induced by 90 min of middle cerebral artery occlusion (MCAO) with nylon monofilament and 22 h of reperfusion in male Sprague-Dawley rats. The animals underwent LIPoC consisting of 1, 2, or 3 cycles, with each occlusion or release lasting for 5 min (5/5), 10 min (10/10), or 15 min (15/15) of bilateral femoral artery occlusion/release. Neurological score, infarct volume, water …
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Turkish Journal of Medical Sciences
We determined the baricity of fentanyl-added bupivacaine or ropivacaine with or without dextrose by analyzing the specific gravity for a better understanding of the final baricity of the intrathecal drug combinations that are supposed to be used for surgery.
Long-Term Results Of Pancreaticoduodenectomy And Endoscopic Resection In The Treatment Of Early Stage Carcinoma Of The Ampulla Of Vater: Case Series And Review Of The Literature, Abdulkadi̇r Dökmeci̇, Mustafa Yakut, Necati̇ Örmeci̇, Hasan Özkan, Gökhan Kabaçam
Long-Term Results Of Pancreaticoduodenectomy And Endoscopic Resection In The Treatment Of Early Stage Carcinoma Of The Ampulla Of Vater: Case Series And Review Of The Literature, Abdulkadi̇r Dökmeci̇, Mustafa Yakut, Necati̇ Örmeci̇, Hasan Özkan, Gökhan Kabaçam
Turkish Journal of Medical Sciences
We retrospectively evaluated 6 cases to explore the role of curative pancreaticoduodenectomy and endoscopic resection of ampulla of Vater tumors. Six patients diagnosed with stage 1 ampullary tumors at Ankara University Hospital between January 1994 and September 2009 were analyzed retrospectively. Icterus was the cardinal symptom in all patients. The median time for the symptoms caused by the lesion of the papilla was 7 weeks in patients with carcinoma. The diameters of the visualized tumors were less than 20 mm. Diabetes mellitus was observed in 2 patients. When the patients were classified according to TNM staging, all patients were in …
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Turkish Journal of Medical Sciences
On CHROMagar medium Candida species form different colors; thus, the medium enables the differentiation of these species from each other as well as from other Candida species. The aim of this study is to investigate the effect of incubation temperatures, incubation times, and CO_2 on the chromogenic properties of CHROMagar. Materials and methods: A total of 112 strains of Candida spp. were used. A 0.5 McFarland suspension of each strain was inoculated onto CHROMagar with a calibrated loop and incubated at 26 °C and 35 °C for 24-48 h in normal atmosphere and in an atmosphere of 5% CO_2. The …
The Prevalence Of Pterygium In Ankara: A Hospital-Based Study, Özge Saraç, Yasi̇n Toklu, Mehmet Şahi̇n
The Prevalence Of Pterygium In Ankara: A Hospital-Based Study, Özge Saraç, Yasi̇n Toklu, Mehmet Şahi̇n
Turkish Journal of Medical Sciences
The prevalence of pterygium in a hospital-based population was analyzed in Ankara, in central Turkey. Materials and methods: This was a retrospective, nonrandomized, and consecutive case study. The medical records of 6470 consecutive patients aged 40 and above who attended the general ophthalmology clinic during a 12-month period from May 2008 to May 2009 were evaluated for the presence of pterygium. Results: The overall prevalence of pterygium was found to be 3.0 % (95% confidence interval (CI): 1.9 to 3.8). It was 3.2% (95% CI: 1.9 to 4.5) and 2.8% (95% CI: 1.4 to 4.5) in men and women, respectively …
Hyaluronidase-1 Expression Is Not A Predictor Of Biochemical Recurrence In Radical Prostatectomy Specimens, Bayram Güner, Sidika Şeyma Özkanli, Turhan Çaşkurlu, Asif Yildirim, Mehmet Cenk Gürbüz, Itir Ebru Zemheri̇
Hyaluronidase-1 Expression Is Not A Predictor Of Biochemical Recurrence In Radical Prostatectomy Specimens, Bayram Güner, Sidika Şeyma Özkanli, Turhan Çaşkurlu, Asif Yildirim, Mehmet Cenk Gürbüz, Itir Ebru Zemheri̇
Turkish Journal of Medical Sciences
The purposes of this study were to evaluate the rate of biochemical recurrence among patients who underwent radical prostatectomy due to localized prostate cancer, assess the risk factors of biochemical recurrence, and investigate its relation with hyaluronidase-1 (HYAL-1). Materials and methods: We retrospectively evaluated the data of 112 patients who underwent radical retropubic prostatectomy. HYAL-1 expression was evaluated immunohistochemically and staining was graded as mild, moderate, and severe. Two blinded pathologists evaluated the specimens. The relation among preoperative pathologic findings that were detected in transrectal ultrasound (TRUS) guided biopsy, specimens of radical prostatectomy in the final stage, and biochemical recurrence …
Improving Electrocardiogram Interpreting Skills Among Primary Care Physicians In Turkey, Turan Set, Zekeri̇ya Aktürk, Mutlu Büyüklü, Zeli̇ha Cansever, Ümmü Zeynep Avşar, Ümi̇t Avşar, Memet Işik, Hami̇t Acemoğlu
Improving Electrocardiogram Interpreting Skills Among Primary Care Physicians In Turkey, Turan Set, Zekeri̇ya Aktürk, Mutlu Büyüklü, Zeli̇ha Cansever, Ümmü Zeynep Avşar, Ümi̇t Avşar, Memet Işik, Hami̇t Acemoğlu
Turkish Journal of Medical Sciences
To investigate the improvement in electrocardiogram (ECG) interpreting skills after a standardized ECG interpreting program as a continuous medical education activity among primary care physicians. Materials and methods: The study was conducted in Turkey between December 2006 and October 2010. Out of the 81 provinces in Turkey, 17 were randomly selected and all physicians were invited to take the course on a voluntary basis and in total 798 physicians agreed to participate. The course was a half-day program. A test was applied to the participants before and after the training. The results of 781 participants were analyzed. Results: Of the …
Microalbumin Excretion And Outcome In Children With Multicystic Dysplastic Kidney, İpek Aki̇l, Neşe Biyikli, Pinar Yazici, Beyhan Cengi̇z Özyurt, Hari̇ka Alpay
Microalbumin Excretion And Outcome In Children With Multicystic Dysplastic Kidney, İpek Aki̇l, Neşe Biyikli, Pinar Yazici, Beyhan Cengi̇z Özyurt, Hari̇ka Alpay
Turkish Journal of Medical Sciences
To present the long-term follow-up results of children with multicystic dysplastic kidney (MCDK) and urinary microalbumin excretion levels in order to evaluate whether there is an increased risk of renal damage or not. Materials and methods: Thirty-three children with the diagnosis of MCDK who had been followed up by the nephrology outpatient clinic between 2002 and 2009 were invited to participate in the study. Twenty-six healthy children were investigated as a control group for microalbumin/creatinine ratio (µg/g creatinine). The mean age at diagnosis, the duration of follow-up, accompanying urinary tract abnormalities, attacks of urinary tract infection (UTI), contralateral kidney size, …
Tularemia As A Result Of Outdoor Activities For Children In The Countryside, Şaban Gürcan, Gamze Varol Saraçoğlu, Aynur Karadeni̇zli̇, Emi̇ne Neşe Özkayin, Şemsi̇ Zafer Öztürk, Cemal Çi̇çek, Bi̇nay Vatansever
Tularemia As A Result Of Outdoor Activities For Children In The Countryside, Şaban Gürcan, Gamze Varol Saraçoğlu, Aynur Karadeni̇zli̇, Emi̇ne Neşe Özkayin, Şemsi̇ Zafer Öztürk, Cemal Çi̇çek, Bi̇nay Vatansever
Turkish Journal of Medical Sciences
To investigate the features of a new tularemia outbreak that occurred in the Thrace region. Materials and methods: The research team visited the village after the identification of the index case. Serum and throat samples were taken from 41 villagers who were examined, and environmental samples were taken in order to identify the source of the outbreak. Culture, serology, and molecular methods were used to search for Francisella tularensis in these samples. Results: A total of 8 children were diagnosed with tularemia. The adults and all of the other children were seronegative for tularemia. All of the patients had a …
Comparison Of Two Different Right-Sided Double-Lumen Tubes With Different Designs, Hi̇lal Sazak, Uğur Göktaş, Ali̇ Alagöz, Çi̇lsem Sevgen Demi̇rbaş, Özlem Güven, Eser Şavkilioğlu
Comparison Of Two Different Right-Sided Double-Lumen Tubes With Different Designs, Hi̇lal Sazak, Uğur Göktaş, Ali̇ Alagöz, Çi̇lsem Sevgen Demi̇rbaş, Özlem Güven, Eser Şavkilioğlu
Turkish Journal of Medical Sciences
To compare usage of 2 right-sided double-lumen tubes (RDLTs) with different designs in thoracic anesthesia. Although the left-sided double-lumen tube (DLT) is preferred, the RDLT is necessary in some circumstances. Materials and methods: A total of 40 patients undergoing left thoracotomy were divided into 2 groups receiving a Rüsch or Sheridan RDLT. The position of the RDLT was verified by clinical evaluation. It was also checked by fiberoptic bronchoscope (FOB). When malposition was detected, it was corrected using the FOB. The correct installation time of the RDLT, frequency of bronchoscopy, and left lung collapse time were recorded. Results: According to …
Efficacy Of Azithromycin For Prevention Of Bronchopulmonary Dysplasia (Bpd), Manizheh Mostafa Gharehbaghi, Ali Peirovifar, Mortaza Ghojazadeh, Majid Mahallei
Efficacy Of Azithromycin For Prevention Of Bronchopulmonary Dysplasia (Bpd), Manizheh Mostafa Gharehbaghi, Ali Peirovifar, Mortaza Ghojazadeh, Majid Mahallei
Turkish Journal of Medical Sciences
Bronchopulmonary dysplasia (BPD) remains one of the most serious and challenging complications in premature infants. This study was conducted to evaluate the efficacy of azithromycin in the prevention of BPD in very low birth weight preterm infants Materials and methods: Preterm neonates with birth weight less than 1500 g were enrolled in a prospective randomized controlled clinical trial. One hundred eight neonates were randomly allocated to the intervention group (n = 56) or control group (n = 52). The intervention group received oral azithromycin 10 mg/kg for 1 week followed by 5 mg/kg for another week. The outcome measures were …