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Articles 4681 - 4710 of 8080
Full-Text Articles in Medicine and Health Sciences
Distribution Of Prothrombin G20210a, Factor V Leiden, And Mthfr C677t Mutations In The Middle Black Sea Area (Tokat) Of Turkey, Şemsetti̇n Şahi̇n, İsmai̇l Benli̇, Leyla Aydoğan
Distribution Of Prothrombin G20210a, Factor V Leiden, And Mthfr C677t Mutations In The Middle Black Sea Area (Tokat) Of Turkey, Şemsetti̇n Şahi̇n, İsmai̇l Benli̇, Leyla Aydoğan
Turkish Journal of Medical Sciences
To determine the distribution frequencies of prothrombin (factor II) G20210A, factor V Leiden, and methylenetetrahydrofolate reductase (MTHFR) C677T mutations in Tokat Province and the middle Black Sea area of Turkey. Materials and methods: The study group consisted of 243 patients who presented to our center with thrombosis and other complaints. Written permission from patients was obtained. DNA was isolated from the blood samples of these patients. Mutation analyses were conducted using the real-time polymerase chain reaction (RT-PCR) method. The data were subjected to statistical analyses. Results: According to the results of the study, factor V Leiden was detected in 37 …
The Levels Of Serum Chemokines In Patients With Behçet's Disease, İbrahi̇m Kökçam, Di̇lara Turgut, Nafi̇ye Fulya İlhan, Demet Çi̇çek
The Levels Of Serum Chemokines In Patients With Behçet's Disease, İbrahi̇m Kökçam, Di̇lara Turgut, Nafi̇ye Fulya İlhan, Demet Çi̇çek
Turkish Journal of Medical Sciences
As chemokines are involved in the regulation of immune responses and inflammatory reactions, this study aimed to investigate the serum levels of some chemokines to determine whether they play roles in the pathogenesis of Behçet's disease (BD). Materials and methods: The study comprised 64 cases, allocated to active or inactive patient groups. The levels of serum macrophage inflammatory protein-1\alpha (MIP-1\alpha), epithelial neutrophil-activating protein-78 (ENA-78), and neutrophil-activating peptide-2 (NAP-2) were measured. Results: The serum levels of MIP-1\alpha and ENA-78 were statistically higher in BD patients than controls (P = 0.032 and P = 0.023, respectively). However, NAP-2 levels did not differ …
The Relationship Between Insulin Resistance And Carotid Artery Intima-Media Thickness In Obese And Morbidly Obese Women, Gülçi̇n Cengi̇z Ecemi̇ş, Hakki Kahraman, Mehmet Seli̇m Nural, Hali̇l Serdar Aslan, Ayşegül Atmaca
The Relationship Between Insulin Resistance And Carotid Artery Intima-Media Thickness In Obese And Morbidly Obese Women, Gülçi̇n Cengi̇z Ecemi̇ş, Hakki Kahraman, Mehmet Seli̇m Nural, Hali̇l Serdar Aslan, Ayşegül Atmaca
Turkish Journal of Medical Sciences
To compare insulin resistance and carotid intima-media thickness (IMT) between obese, morbidly obese, and healthy women and demonstrate whether there is a relation between these parameters, focusing mainly on morbidly obese women. Materials and methods: Twenty-five morbidly obese women (body mass index (BMI) => 40 kg/m^²), 25 obese women (BMI 30-39.9 kg/m^²), and 25 age-matched healthy women (BMI 18.5-24.9 kg/m^²) were recruited for the study. None of the subjects had diabetes mellitus. BMI, waist-to-hip ratio, lipid profiles, fasting glucose and insulin levels, insulin resistance (by HOMA), and IMT (common carotid, internal carotid, and bifurcation measurements) were compared among the 3 …
Investigation Of Serum Paraoxonase-1 Activity And Lipid Levels In Patients With Hyperthyroidism, Gülden Başkol, Kiymet Dolbun Seçki̇n, Fahri̇ Bayram, Fati̇h Tanriverdi̇
Investigation Of Serum Paraoxonase-1 Activity And Lipid Levels In Patients With Hyperthyroidism, Gülden Başkol, Kiymet Dolbun Seçki̇n, Fahri̇ Bayram, Fati̇h Tanriverdi̇
Turkish Journal of Medical Sciences
The present study was designed to investigate the relationship among the serum paraoxonase-1 (PON-1) activity, lipid levels, and thyroid hormone status in patients with hyperthyroidism. Materials and methods: The study group comprised 30 patients with primary hyperthyroidism and 18 normal healthy controls who were matched for age and sex. Serum PON-1 activity was determined by spectrophotometric methods. Results: Serum PON-1 activity was found to be lower in patients compared to controls (P < 0.05). Free triiodothyronine (T3) and free thyroxine (T4) levels were significantly higher in the patient group compared to the control group (P < 0.001 and P < 0.001 respectively). Thyroid-stimulating hormone (TSH) and total cholesterol values were found to be lower in patients than in the controls (P < 0.001 and P < 0.001 respectively). Low-density lipoprotein cholesterol levels were found to be decreased in patients compared to controls (P < 0.005). Triglyceride and high-density lipoprotein cholesterol levels were not significantly different between the 2 groups (P > 0.05). Serum PON-1 activity was found to be negatively correlated with free T4 levels (r = -0.324, P < 0.05) and positively correlated with total cholesterol (r = 0.330, P < 0.05) and TSH levels (r = 0.577, P < 0.001). Conclusion: Our PON-1 results show that there is decreased antioxidant defense in patients with hyperthyroidism. Therefore, we think that effective antioxidant therapy to increase PON-1 activity may be a therapeutic option in patients with hyperthyroidism.
Predictors Of Warfarin Use In Patients With Non-Valvular Atrial Fibrillation Who Presented To The Cardiology Outpatient Clinic Of A Tertiary Hospital In Turkey: An Observational Study, Faruk Ertaş, Hasan Kaya, Zuhal Aritürk Atilgan, Mehmet Ali̇ Elbey, Mesut Aydi̇n, Mehmet Ata Akil, Mustafa Oylumlu, Mehmet Siddik Ülgen
Predictors Of Warfarin Use In Patients With Non-Valvular Atrial Fibrillation Who Presented To The Cardiology Outpatient Clinic Of A Tertiary Hospital In Turkey: An Observational Study, Faruk Ertaş, Hasan Kaya, Zuhal Aritürk Atilgan, Mehmet Ali̇ Elbey, Mesut Aydi̇n, Mehmet Ata Akil, Mustafa Oylumlu, Mehmet Siddik Ülgen
Turkish Journal of Medical Sciences
The aim of this study was to investigate the predictors of warfarin use in patients with non-valvular atrial fibrillation (AF). This study was the first to be conducted in a Turkish population. Materials and methods: Patients who presented to our outpatient clinic with the diagnosis of AF between September 2008 and October 2009 were enrolled. The patients were classified according to the CHADS2 risk scoring system recommended by the AHA/ACC/ESC guidelines for the classification of stroke risk in non-valvular AF patients. The probable variables influencing the use of warfarin were determined as age, sex, income level, healthcare coverage, lifestyle, place …
Histopathological Effects Of The Food Contaminant Furan On Some Endocrine Glands Of Prepubertal Male Rats, Eli̇f Karacaoğlu, Güldeni̇z Selmanoğlu, Aysun Kiliç
Histopathological Effects Of The Food Contaminant Furan On Some Endocrine Glands Of Prepubertal Male Rats, Eli̇f Karacaoğlu, Güldeni̇z Selmanoğlu, Aysun Kiliç
Turkish Journal of Medical Sciences
To evaluate the toxicity of furan on the thyroid gland, adrenal gland, and pancreas of prepubertal male rats. Materials and methods: Furan was administered orally to 3-4-week-old male rats at doses of 2, 4, and 8 mg kg^{-1} day^{-1} by dissolving in corn oil for 90 days. The rats were sacrificed by cervical dislocation at the end of the experiment. Their endocrine glands including the thyroid gland, adrenal gland, and pancreas were removed and weighed. Tissues were examined morphologically and histopathologically under a light microscope. Results: Organ and relative organ weights of rats did not change with furan administration. Histopathological …
2-[18f]-Fluoro–2-Deoxy-D-Glucose Positron Emission Tomography In The Evaluation Of Breast Lesions And Axillary Involvement: A Comparison With Mammography And Histopathological Diagnosis, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Semi̇h Görgülü, Mehmet Fati̇h Can, Hani̇fe Asli Ayan Eke, Semra İnce, Erkan Öztürk, Ramazan Yildiz, Mehmet Ali̇ Özgüven
2-[18f]-Fluoro–2-Deoxy-D-Glucose Positron Emission Tomography In The Evaluation Of Breast Lesions And Axillary Involvement: A Comparison With Mammography And Histopathological Diagnosis, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Semi̇h Görgülü, Mehmet Fati̇h Can, Hani̇fe Asli Ayan Eke, Semra İnce, Erkan Öztürk, Ramazan Yildiz, Mehmet Ali̇ Özgüven
Turkish Journal of Medical Sciences
The objective of this prospective study was to evaluate the potential role of 2-[18f]-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) in the differentiation of malignant and benign breast masses and the evaluation of axillary lymph node involvement. The secondary objective of this study was to assess the value of FDG PET in the initial staging of patients with breast cancer. Materials and methods: We evaluated 82 lesions in 79 consecutive patients (mean age of 54.4 ± 13.0; age range: 25-82 years) with FDG PET. While ultrasounds were performed in all cases, of the 79 patients, 72 had mammography and 58 had …
Comparison Of The Outcomes Of The Tot Technique Using A Hand-Made Tot Material And A Commercial One, Ahmet Tunç Özdemi̇r, Serkan Altinova, Haci İbrahi̇m Çi̇men, Ege Can Şerefoğlu, Hasbey Hakan Koyuncu, Mesut Gürdal
Comparison Of The Outcomes Of The Tot Technique Using A Hand-Made Tot Material And A Commercial One, Ahmet Tunç Özdemi̇r, Serkan Altinova, Haci İbrahi̇m Çi̇men, Ege Can Şerefoğlu, Hasbey Hakan Koyuncu, Mesut Gürdal
Turkish Journal of Medical Sciences
The purpose of this study was to compare the effectiveness of handmade transobturator tape (TOT) devices (tailored polypropylene mesh by the surgeon during the operation) with commercially available ones. Materials and methods: We included 78 consecutive women with the complaint of pure stress urinary incontinence recalcitrant to lifestyle modifications, pelvic floor muscle training, and medical treatment. The patients underwent TOT procedures either with a commercially available product (I-Stop, CL Medical, Lyon, France) (group 1) or with a device prepared during the operation with polypropylene mesh of 35 × 2 cm in size (Prolen®, Ethicon Inc., Somerville, New Jersey, USA) (group …
Evaevaluation Of Glucose Challenge And Oral Glucose Tolerance Test Results In Pregnancy And Estimation Of Prevalence Of Gestational Diabetes Mellitus At Sema Hospital In İstanbul, Ahmet Ruhi̇ Toraman, Ahmet Gürel, Zeynep Ulusal, Gülni̇hal Bülbül, Ayşe Gülçi̇n Demi̇rdöven, Melek Uzun, Ali̇ Özcan, Muzaffer Çakmak
Evaevaluation Of Glucose Challenge And Oral Glucose Tolerance Test Results In Pregnancy And Estimation Of Prevalence Of Gestational Diabetes Mellitus At Sema Hospital In İstanbul, Ahmet Ruhi̇ Toraman, Ahmet Gürel, Zeynep Ulusal, Gülni̇hal Bülbül, Ayşe Gülçi̇n Demi̇rdöven, Melek Uzun, Ali̇ Özcan, Muzaffer Çakmak
Turkish Journal of Medical Sciences
This study was designed to evaluate glucose screening and oral glucose tolerance test results, and to assess the prevalence of gestational diabetes in pregnant patients admitted to our hospital. Materials and methods: This retrospective study was carried out at Sema Hospital in İstanbul, Turkey. The study subjects were recruited between January 2006 and August 2009. A glucose challenge test (GCT) was given to 1681 pregnant women and based on the results 494 went on to take an oral glucose tolerance test (OGTT). A diagnosis of gestational diabetes mellitus (GDM) was made according to the criteria defined by the National Diabetes …
Concomitant Carotid Endarterectomy And Off-Pump Coronary Artery Bypass Grafting In Coexistent Carotid And Coronary Artery Diseases, Murat Kurtoğlu, Mehmet Şanser Ateş, İbrahi̇m Duvan, Burak Emre Onuk, Yahya Hali̇dun Karagöz
Concomitant Carotid Endarterectomy And Off-Pump Coronary Artery Bypass Grafting In Coexistent Carotid And Coronary Artery Diseases, Murat Kurtoğlu, Mehmet Şanser Ateş, İbrahi̇m Duvan, Burak Emre Onuk, Yahya Hali̇dun Karagöz
Turkish Journal of Medical Sciences
To analyze the results of our experience with a combined procedure via off-pump coronary artery bypass (OPCABG) and carotid endarterectomy (CEA) retrospectively. Materials and methods: Eighty-four patients underwent OPCABG and CEA concomitantly between 1998 and 2011. Thirty (35.7%) patients had a cardiac history of myocardial infarction (MI), 13 (15.6%) had unstable angina (USAP), and 27 (32.1%) had USAP together with MI, whereas 14 (16.6%) were asymptomatic. Forty-two (50%) patients showed no neurological symptoms, 20 (23.8%) had transient ischemic attacks (TIAs), 21 (25%) suffered from stroke, and 1 (1.2%) experienced both. CEA was performed before OPCABG in all of the patients. …
Genotyping Of Giardia Intestinalis Isolated From People Living In Sivas, Turkey, Serpi̇l Değerli̇, Naci̇ Değerli̇, Ali̇ Çeli̇ksöz, Semra Özçeli̇k
Genotyping Of Giardia Intestinalis Isolated From People Living In Sivas, Turkey, Serpi̇l Değerli̇, Naci̇ Değerli̇, Ali̇ Çeli̇ksöz, Semra Özçeli̇k
Turkish Journal of Medical Sciences
The technique of polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) genotyping was used to characterise morphologically identical isolates of Giardia intestinalis from human stool samples. Materials and methods: In this study a total of 17 trophozoite samples, obtained either directly from stool samples or after excystation, or by duodenal aspiration, were used. A set of primers was chosen to amplify the different regions of triose phosphate isomerase (tpi) and a segment of the glutamate dehydrogenase (gdh) genes. A single-stranded conformational polymorphism technique was also used in an attempt to discriminate among some subgroups. Results: Only primers of the 683-bp segment …
Doppler Sonography Of Hemodynamic Changes Of The Celiac Artery In Chronic Active Gastritis, Asli Köktener, Fatma Gül Cansel Türkay, Eli̇fe Erarslan, Reyhan Bayrak, Si̇bel Yeni̇dünya, Kayihan Akin, Di̇lek Kösehan, Banu Çakir
Doppler Sonography Of Hemodynamic Changes Of The Celiac Artery In Chronic Active Gastritis, Asli Köktener, Fatma Gül Cansel Türkay, Eli̇fe Erarslan, Reyhan Bayrak, Si̇bel Yeni̇dünya, Kayihan Akin, Di̇lek Kösehan, Banu Çakir
Turkish Journal of Medical Sciences
In this study, we determined how Doppler parameters of the celiac artery (CA) are affected in patients with chronic gastritis. Materials and methods: We examined 23 patients (group 1) with chronic active gastritis (diagnosed by endoscopy and histology) and 19 asymptomatic control subjects (group 2) with duplex Doppler ultrasonography. The patient group (group 1) was classified in 2 subgroups according to the severity of the inflammation. The second classification was done according to the presence of the Helicobacter pylori infection within group 1. Mean peak systolic velocity (PSV), end-diastolic velocity (EDV), resistive index (RI), and pulsatility index (PI) of the …
Characterization Of Uropathogenic Escherichia Coli Strains Obtained From Urology Outpatient Clinic Of Ege Medical Faculty In İzmir, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Characterization Of Uropathogenic Escherichia Coli Strains Obtained From Urology Outpatient Clinic Of Ege Medical Faculty In İzmir, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Turkish Journal of Medical Sciences
To identify the papG gene and its allelic variation in uropathogenic Escherichia coli (UPEC) strains isolated from patients with acute pyelonephritis and cystitis. Materials and methods: Seventy-five E. coli strains isolated from patients admitted to the University of Ege Medical Faculty urology outpatient clinic were isolated and identified phenotypically. All of these strains were examined for the papG gene and allelic distribution of this gene with the multiplex polymerase chain reaction technique. Results: papG genes were found in 24 of 75 E. coli strains. Of these 24 strains, 7 (29%) had papG class II only, 8 (33%) had class III …
Caudal Epidural Block For Elderly Patients Who Have Limited Cardiac Reserve, Emi̇ne Arzu Köse, Ali̇ye Öztürk, Gülnaz Ateş, Alparslan Apan
Caudal Epidural Block For Elderly Patients Who Have Limited Cardiac Reserve, Emi̇ne Arzu Köse, Ali̇ye Öztürk, Gülnaz Ateş, Alparslan Apan
Turkish Journal of Medical Sciences
The choice of anesthetic technique based on its advantages and disadvantages in elderly patients will inevitably be influenced by the patient's comorbidities, such as cardiovascular disease, diabetes mellitus, stroke, renal insufficiency, and pulmonary disease. The patient's underlying cardiac conditions, although apparently stable at present, may become manifest during perioperative stresses. Caudal epidural block should be taken into consideration as a safe and effective anesthetic technique for the elderly patients who have limited cardiac reserve and comorbidities. Six patients with low ejection fraction and poor functional status due to ischemic cardiac disease scheduled for surgery under caudal epidural block are presented.
Molecular Typing And Sequencing Of Adenovirus Isolated From A Conjunctivitis Outbreak In A Neonatal Intensive Care Unit By Pcr, Candan Çi̇çek, Tamer Şanlidağ, Betül Si̇yah Bi̇lgi̇n, Hüsnü Pullukçu, Si̇nem Akçali, Özge Altun Köroğlu, Mehmet Yalaz, Ni̇lgün Kültürsay
Molecular Typing And Sequencing Of Adenovirus Isolated From A Conjunctivitis Outbreak In A Neonatal Intensive Care Unit By Pcr, Candan Çi̇çek, Tamer Şanlidağ, Betül Si̇yah Bi̇lgi̇n, Hüsnü Pullukçu, Si̇nem Akçali, Özge Altun Köroğlu, Mehmet Yalaz, Ni̇lgün Kültürsay
Turkish Journal of Medical Sciences
We aimed to evaluate the molecular typing of adenovirus isolated during an epidemic at the Ege University Children's Hospital neonatal intensive care unit (NICU). Materials and methods: During the NICU outbreak management, 40 clinical samples (from 15 newborn infants and 25 health care providers) were sent to a microbiology laboratory in viral transport media. All the samples were processed using a direct fluorescent antibody (DFA) test and a shell vial cell culture followed by adenovirus polymerase chain reaction (PCR) and DNA sequencing. PCR and DNA sequencing for adenovirus hexon gene hypervariable regions 1-6 were done after DNA extraction from clinical …
Effects Of Cigarette Smoking On Male Fertility, Farkhunda Nadeem, Amin Fahim, Saira Bugti
Effects Of Cigarette Smoking On Male Fertility, Farkhunda Nadeem, Amin Fahim, Saira Bugti
Turkish Journal of Medical Sciences
This study was done to compare the various semen parameters of infertile male smokers with nonsmokers and also draw comparisons among light, moderate, and heavy smokers. Materials and methods: A total of 130 infertile male patients were included in this study from the outpatient department of Gynecology and Obstetrics at Liaquat University of Medical and Health Sciences, Hyderabad, from January 2010 to May 2010. The subjects were infertile males married for more than 1 year, and they were selected randomly. The subjects were thoroughly interviewed and were selected according to inclusion criteria. History about cigarette smoking and its duration was …
Minimum Inhibitory And Minimum Bactericidal Concentrations Of Boron Compounds Against Several Bacterial Strains, Murat Tolga Yilmaz
Minimum Inhibitory And Minimum Bactericidal Concentrations Of Boron Compounds Against Several Bacterial Strains, Murat Tolga Yilmaz
Turkish Journal of Medical Sciences
Boron compounds are essential micronutrients for many organisms. However, they negatively affect plant, soil, and water microflora if excessive amounts exist in irrigation water. Therefore, this study aimed to define the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of boric acid and borax by selecting the bacteria that can survive in all environments. Materials and methods: The antibacterial efficacy of boric acid and borax against several bacterial strains was evaluated 3 times with the macrodilution broth method. Results: The MICs and MBCs of boric acid were obtained as 3.80 mg/mL, 3.80 mg/mL, 7.60 mg/mL, and 7.60 mg/mL against …
Circulating Levels Of Igf-I And Igfbp-3 In Gastric Cancer, Konca Altinkaynak, Mehmet Bi̇li̇ci̇, Nuri̇ Bakan, Fati̇h Akçay
Circulating Levels Of Igf-I And Igfbp-3 In Gastric Cancer, Konca Altinkaynak, Mehmet Bi̇li̇ci̇, Nuri̇ Bakan, Fati̇h Akçay
Turkish Journal of Medical Sciences
To explore the causative mechanism of gastric carcinoma and to investigate the roles of circulating IGF-I and IGFBP-3 in gastric cancer. Materials and methods: Serum IGF-I and IGFBP-3 concentrations were measured using a 2-site coated tube immunoradiometric assay. Results: Serum IGF-I and IGFBP-3 values in gastric cancer patients were significantly lower compared to those in the control group. The difference between serum IGF-I/IGFBP-3 in patients and the control group was not significant. Conclusion: The low serum IGF-I and IGFBP-3 levels detected in patients with gastric cancer could be due to decreased synthesis or increased catabolism of IGF-I or both. It …
Investigation Of The Clinical And Hematological Significance Of The First Observed Hemoglobin Ernz Variant [Β123(H1) Thr>Asn] In The Turkish Population, Ramazan Güneşaçar, Muhammet Murat Çeli̇k, Oktay Hasan Öztürk, Mustafa Çeli̇k, Cemi̇l Tümer, Tanju Çeli̇k
Investigation Of The Clinical And Hematological Significance Of The First Observed Hemoglobin Ernz Variant [Β123(H1) Thr>Asn] In The Turkish Population, Ramazan Güneşaçar, Muhammet Murat Çeli̇k, Oktay Hasan Öztürk, Mustafa Çeli̇k, Cemi̇l Tümer, Tanju Çeli̇k
Turkish Journal of Medical Sciences
In this report, we aimed to investigate the clinical and hematological significance of the first observed hemoglobin Ernz variant in the Turkish population. Materials and methods: We identified the Hb Ernz variant in 3 nonrelated females (Probands 1, 2, and 3). Proband 1’s family was also included the study. Hematological data were obtained with an automated cell counter and routine methodology. The beta-globin gene was sequenced by automatic sequencing. Results: Proband 1 was detected as a combination of Hb Ernz/Hb S without any clinical symptoms. Her sister and brother had to be an Hb Ernz/Hb S combination. Her mother and …
Investigating Virulence Factors Of Clinical Candida Isolates In Relation To Atmospheric Conditions And Genotype, Melek İnci̇, Mustafa Altay Atalay, Ayşe Nedret Koç, Erkan Yula, Ömer Evi̇rgen, Süleyman Durmaz, Gonca Demi̇r
Investigating Virulence Factors Of Clinical Candida Isolates In Relation To Atmospheric Conditions And Genotype, Melek İnci̇, Mustafa Altay Atalay, Ayşe Nedret Koç, Erkan Yula, Ömer Evi̇rgen, Süleyman Durmaz, Gonca Demi̇r
Turkish Journal of Medical Sciences
To investigate some virulence factors in Candida species isolated from patients with suspected invasive fungal infection and to identify their relationship with Candida genotypes. Materials and methods: Overall 45 isolates (20 Candida albicans and 25 non-albicans Candida spp.) genotyped by rep-PCR were included in this study. Virulence factors were studied in both aerobic and anaerobic conditions. In isolates, egg yolk agar was used for determining phospholipase activity, while bovine serum albumin agar was used for proteinase activity, Tween-80 medium for esterase activity, and Sabouraud dextrose agar with sheep blood for hemolysin activity. Biofilm formation was detected by the microplate method. …
The Effect Of Intermittent Fasting And Water Restriction On Myocardial Ischemia/Reperfusion-Induced Arrhythmia In Rats, Sali̇h Tunç Kaya, Ömer Bozdoğan
The Effect Of Intermittent Fasting And Water Restriction On Myocardial Ischemia/Reperfusion-Induced Arrhythmia In Rats, Sali̇h Tunç Kaya, Ömer Bozdoğan
Turkish Journal of Medical Sciences
To investigate the effect of intermittent fasting and water restriction on ischemia/reperfusion-induced arrhythmias. Materials and methods: Six minutes of ischemia followed by 6 min of reperfusion was produced by the ligation and then releasing of the left coronary artery. Intermittent fasting and water restriction were applied during 1 month for 12 h/day. The duration, type, and incidence of arrhythmias during reperfusion and the survival rate at the end of reperfusion were determined and compared. Results: The score of arrhythmia that was determined using the type and duration of arrhythmia did not show significant differences among groups. The arrhythmic period was …
Maxillofacial Trauma With Head Injuries At A Tertiary Care Hospital In Chitwan, Nepal: Clinical, Medico-Legal, And Critical Care Concerns, Santosh Kumar Yadav, Birendra Kumar Mandal, Abhishek Karn, Ajit Kumar Sah
Maxillofacial Trauma With Head Injuries At A Tertiary Care Hospital In Chitwan, Nepal: Clinical, Medico-Legal, And Critical Care Concerns, Santosh Kumar Yadav, Birendra Kumar Mandal, Abhishek Karn, Ajit Kumar Sah
Turkish Journal of Medical Sciences
Maxillofacial trauma is commonly associated with other injuries, predominantly head injuries. The present study aimed to evaluate types of injury, management, and outcome of patients sustaining maxillofacial trauma and concomitant cranial injuries. Materials and methods: A retrospective study was carried out in the department of oral and maxillofacial surgery. A case series of 63 patients who were admitted to the intensive care unit with maxillofacial trauma and head injuries was evaluated. The data were then compiled systematically and analyzed using SPSS for Windows and values of P < 0.05 were considered significant and P < 0.0001 as highly significant. Results: Among the 63 patients, the majority of them had had roadside accidents (90%) and there was a predominant sex bias with a male to female ratio of 7:1. Fractured maxilla and nasal bones were the most commonly encountered injuries (49.21%), followed by mandibular fractures (38.09%). Forty-two patients (66.67%) required mechanical ventilation, tracheostomy was needed in 19 (30.16%) patients, and 42 (66.67%) patients were operated on for head injuries. The majority of the victims were aged between 15 and 40 years. Conclusion: Maxillofacial trauma with head injuries demands special attention as airway compromise is invariably present. Equally critical is the surgical intervention as simultaneously cranial and maxillofacial surgeries were performed. Preventive measures and legislation regarding traffic rules require a review also as the higher incidence of accidents among young adults has acquired epidemic status.
Effects Of Combined Oral Contraceptives On The Skin Of Mice, Nibras Hatim Khamees, Insaf Jasim Mahmoud, Amal Al Khateeb
Effects Of Combined Oral Contraceptives On The Skin Of Mice, Nibras Hatim Khamees, Insaf Jasim Mahmoud, Amal Al Khateeb
Turkish Journal of Medical Sciences
To find the effects of a combination of 2 widely used contraceptives, ethinyl estradiol and cyproterone acetate (ECPA), on skin and sebaceous gland morphology and dermal vascularity of mice. Materials and methods: Female mice were divided into groups: treatment with ECPA for 1 month (T) and its control (C); and cessation of treatment for an additional month (recovery, R) and its control (CR). Body weight, skin histology and morphometry, and vaginal smears were performed and analyzed. Results: In the T and R groups, there was a significant increase in epidermal and dermal thickness and dermal vascularity. In group T, the …
Assessment Of Haematology Patients With Confirmed H1n1 Positivity, Füsun Özdemi̇rkiran, Hüsnü Pullukçu, Candan Çi̇çek, Seçki̇n Çağirgan, Murat Tombuloğlu, Fi̇li̇z Vural, Güray Saydam
Assessment Of Haematology Patients With Confirmed H1n1 Positivity, Füsun Özdemi̇rkiran, Hüsnü Pullukçu, Candan Çi̇çek, Seçki̇n Çağirgan, Murat Tombuloğlu, Fi̇li̇z Vural, Güray Saydam
Turkish Journal of Medical Sciences
H1N1 influenza virus infections in immunosuppressive patients cause complications. Clinical and laboratory findings of H1N1 positive haematology patients were evaluated in this study. Materials and methods: The "H1N1 Swine Influenza Suspicious Case Notification Form and Inpatient Follow-up Form" was prepared for 15 patients with suspected H1N1 infection between October 2009 and May 2010. H1N1 was detected by real-time RT-PCR assay. For all cases medical records were reviewed for clinical, demographic, and haematologic information. Results: H1N1 positivity was confirmed using real-time RT-PCR in 9 out of 15 patients (11 men, 4 women). One of the 9 patients had been followed up …
Problem Of Antibiotic Resistance In Patients With Acute Bacterial Cystitis And Treatment Options, Ahmet Karakaş, Vedat Turhan
Problem Of Antibiotic Resistance In Patients With Acute Bacterial Cystitis And Treatment Options, Ahmet Karakaş, Vedat Turhan
Turkish Journal of Medical Sciences
No abstract provided.
The Factors Affecting Noninvasive Mechanical Ventilation Failure In Copd Exacerbations, Feza Bacakoğlu, Mehmet Sezai̇ Taşbakan, Özen Kaçmaz Başoğlu, Adnan Tolga Öz, Sedat Ürkmez, Meltem Mi̇di̇lli̇, Pervi̇n Korkmaz Ekren, Alev Gürgün
The Factors Affecting Noninvasive Mechanical Ventilation Failure In Copd Exacerbations, Feza Bacakoğlu, Mehmet Sezai̇ Taşbakan, Özen Kaçmaz Başoğlu, Adnan Tolga Öz, Sedat Ürkmez, Meltem Mi̇di̇lli̇, Pervi̇n Korkmaz Ekren, Alev Gürgün
Turkish Journal of Medical Sciences
To evaluate causes of noninvasive mechanical ventilation (NIMV) failure. The rate of NIMV failure in respiratory failure due to chronic obstructive pulmonary disease (COPD) exacerbations was reported as 5%-40%. Materials and methods: The necessity of endotracheal intubation was accepted as NIMV failure. The causes of NIMV failure were assessed in 54 patients (45 males; mean age: 67.7 ± 11.0 years) treated with NIMV because of COPD exacerbations and respiratory failure in an intensive care unit (ICU). Results: There was NIMV failure in 20 patients (37.0%). The rates of hospital-acquired pneumonia and in-hospital mortality were higher (P = 0.003 and P …
Effects Of Phenolic Acids On Gastrointestinal Smooth Muscle Complications In Streptozotocine-Induced Diabetic Rats, Nurcan Bektaş, Yusuf Öztürk
Effects Of Phenolic Acids On Gastrointestinal Smooth Muscle Complications In Streptozotocine-Induced Diabetic Rats, Nurcan Bektaş, Yusuf Öztürk
Turkish Journal of Medical Sciences
To identify the effects of antioxidants on gastrointestinal smooth muscle complications in 6-week streptozotocine (STZ)-induced diabetic rats. Materials and methods: The following steps were carried out: 1. Three weeks after STZ injection, saline and 10 mg/kg p-OH benzoic, protocatechic, and gallic acids were separately administered to the rat groups every day for 3 weeks. 2. The responses of the fundus and ileum to agonists were recorded using isolated organ bath experiments. Results: Diabetic smooth muscle complications developed in the diabetic rats. The responses of the ileum to acetylcholine increased whereas the responses of the fundus to serotonine decreased in the …
A Rare Presentation Of Brucellosis: Polyradiculopathy And Peripheral Neuritis, Günay Ertem, Gülni̇hal Kutlu, Çi̇ğdem Ataman Hati̇poğlu, Cemal Bulut, Ali̇ Pekcan Demi̇röz
A Rare Presentation Of Brucellosis: Polyradiculopathy And Peripheral Neuritis, Günay Ertem, Gülni̇hal Kutlu, Çi̇ğdem Ataman Hati̇poğlu, Cemal Bulut, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
To present 8 patients with polyradiculopathy or polyradiculoneuritis caused by brucellosis. Polyradiculopathy or polyradiculoneuritis are occasional neurological involvements of brucellosis. Materials and methods: The diagnosis was made with clinical, serological and/or cerebrospinal fluid, and electromyographic examinations. Results: All of the patients except one improved quickly after specific antimicrobial treatment. Furthermore, electrophysiological examinations revealed normal findings in 6 patients. Conclusion: This clinical form of brucellosis is mostly reversible if it is diagnosed earlier and treated effectively.
Laboratory Criteria For Severe Crimean-Congo Haemorrhagic Fever : Letter To The Editor, Mesut Ortatatli, Serdar Ümi̇t Sarici
Laboratory Criteria For Severe Crimean-Congo Haemorrhagic Fever : Letter To The Editor, Mesut Ortatatli, Serdar Ümi̇t Sarici
Turkish Journal of Medical Sciences
No abstract provided.
Effects Of Long-Term Passive Smoking On The Vascular Endothelial Growth Factor And Apoptosis Marker Expression In The Retina And Choroid: An Experimental Study, Sema Dündar, Fati̇h Özcura, İbrahi̇m Meteoğlu, Mehmet Erkut Kara
Effects Of Long-Term Passive Smoking On The Vascular Endothelial Growth Factor And Apoptosis Marker Expression In The Retina And Choroid: An Experimental Study, Sema Dündar, Fati̇h Özcura, İbrahi̇m Meteoğlu, Mehmet Erkut Kara
Turkish Journal of Medical Sciences
To investigate the effects of smoking, reported as a risk factor for age related macular degeneration (ARMD), on the vascular endothelial growth factor (VEGF) expression and apoptosis in the retina and choroid of rats. Materials and methods: This experimental study included 38 Sprague-Dawley rats. The rats were randomly assigned into 4 groups. Groups 1 (males) and 2 (females) were exposed to smoke beginning on day 21 after birth, whereas groups 3 (males) and 4 (females) were not exposed to smoke. At the end of the fourth month, the right eyes of all of the rats were enucleated. Immunohistochemical analysis was …