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Articles 3871 - 3900 of 8080
Full-Text Articles in Medicine and Health Sciences
Seroprevalences And Associated Risk Factors Of Hepatitis B And C In Adults, Mustafa Yildirim, Selma Çakir, Mehmet Faruk Geyi̇k, Davut Özdemi̇r, Ertuğrul Güçlü, Mehmet Çakir
Seroprevalences And Associated Risk Factors Of Hepatitis B And C In Adults, Mustafa Yildirim, Selma Çakir, Mehmet Faruk Geyi̇k, Davut Özdemi̇r, Ertuğrul Güçlü, Mehmet Çakir
Turkish Journal of Medical Sciences
Chronic hepatitis due to hepatitis B and hepatitis C virus infections is the most common cause of chronic liver disease. In this study we aimed to find out seroprevalences and associated risk factors of hepatitis B and C in adults in Düzce. Materials and methods: The sample of study was determined with a cluster-type sampling method. The study included 1321 people, consisting of 667 women and 654 men who were 18 years or older. A questionnaire about demographic information and risk factors was applied. Results: Seroprevalences of HBsAg, anti-HBs, and anti-HCV were 4.8%, 9.4%, and 0.7%, respectively. HBsAg seroprevalences were …
Hormone Replacement Therapy-Related Changes In The Early Postmenopausal Period (Critical Window): An In Vivo Brain Proton Magnetic Resonance Spectroscopy Study, Kamran Mahmutyazicioğlu, Fahri̇ Hali̇t Beşi̇r, Mustafa Bardakçi, Hami̇t Alper Tanriverdi̇, Handan Ankarali
Hormone Replacement Therapy-Related Changes In The Early Postmenopausal Period (Critical Window): An In Vivo Brain Proton Magnetic Resonance Spectroscopy Study, Kamran Mahmutyazicioğlu, Fahri̇ Hali̇t Beşi̇r, Mustafa Bardakçi, Hami̇t Alper Tanriverdi̇, Handan Ankarali
Turkish Journal of Medical Sciences
Findings from clinical studies in postmenopausal women with late initiation of hormone replacement therapy (HRT) that test whether HRT protects cognitive functions in women are inconsistent. The aim of this study was to investigate the effects of HRT on brain metabolite ratios when initiated in the early postmenopausal period (critical window). Materials and methods: Proton magnetic resonance spectrometry (1H MRS) was performed in 4 brain regions of 47 healthy postmenopausal women (21 received HRT, 26 did not). The subjects were aged between 45 and 65 years. The duration of HRT ranged from 1 to 12 years (mean: 6.3 years). The …
Effects Of Conservative Therapy Applied Before Arthroscopic Subacromial Decompression On The Clinical Outcome In Patients With Stage 2 Shoulder Impingement Syndrome, Ali̇ Aydin, Vahi̇t Yildiz, Murat Topal, Kutsi̇ Tuncer, Mehmet Köse, Eyüp Şenocak
Effects Of Conservative Therapy Applied Before Arthroscopic Subacromial Decompression On The Clinical Outcome In Patients With Stage 2 Shoulder Impingement Syndrome, Ali̇ Aydin, Vahi̇t Yildiz, Murat Topal, Kutsi̇ Tuncer, Mehmet Köse, Eyüp Şenocak
Turkish Journal of Medical Sciences
To investigate the effects of conservative therapy applied before arthroscopic subacromial decompression on the clinical outcome in patients with stage 2 shoulder impingement syndrome. Materials and methods: Sixty-eight patients having stage 2 shoulder impingement syndrome and treated with arthroscopic subacromial decompression were included in the study. We divided these patients into 2 groups, whereby 32 (47%) patients received conservative therapy before arthroscopic subacromial decompression and 36 (53%) patients did not receive conservative therapy. We compared both groups in terms of the the Constant, UCLA, and VAS scores for shoulder pain before and after arthroscopic subacromial decompression. Results: Constant, UCLA, and …
Review Of Clinical Experience With Acute Cholecystitis On The Development Of Subsequent Gallstone--Elated Complications, Mustafa Hasbahçeci̇, Orhan Ali̇moğlu, Fati̇h Başak, Tolga Canbak, Abdullah Şi̇şi̇k, Müjgan Çalişkan Evren, Gürhan Baş
Review Of Clinical Experience With Acute Cholecystitis On The Development Of Subsequent Gallstone--Elated Complications, Mustafa Hasbahçeci̇, Orhan Ali̇moğlu, Fati̇h Başak, Tolga Canbak, Abdullah Şi̇şi̇k, Müjgan Çalişkan Evren, Gürhan Baş
Turkish Journal of Medical Sciences
Recently, surgery during admission has been advocated for acute cholecystitis, rather than delayed surgery after conservative treatment. This study was designed to perform early surgeries and analyze the criteria used for conservative management followed by delayed surgery. Materials and methods: After implementation of a study with the aim of performing early surgery, a retrospective review using a prospective database during the period of June 2009 to June 2011 was established. Early surgery during index hospitalization was offered to all patients, except those having criteria for conservative management. Results: There were 118 patients admitted for acute cholecystitis. Early and delayed surgeries …
Evaluation Of Apoptotic Cell Death Following Transient Maternal Hypotension In Fetal Rat Brain: Temporal Pattern Within The First 24 H After Procedure, Si̇bel Bayrak, Bi̇lge Pehli̇vanoğlu, Ayşe Meltem Sevgi̇li̇, Zeynep Di̇cle Balkanci, Hami̇t Özyürek, Pergi̇n Ati̇lla, Ayşe Nur Çakar, Fatma Banu Anlar
Evaluation Of Apoptotic Cell Death Following Transient Maternal Hypotension In Fetal Rat Brain: Temporal Pattern Within The First 24 H After Procedure, Si̇bel Bayrak, Bi̇lge Pehli̇vanoğlu, Ayşe Meltem Sevgi̇li̇, Zeynep Di̇cle Balkanci, Hami̇t Özyürek, Pergi̇n Ati̇lla, Ayşe Nur Çakar, Fatma Banu Anlar
Turkish Journal of Medical Sciences
To explore the effects of maternal transient systemic hypotension on apoptotic neuronal death in an intrauterine fetal rat brain during the first 24 h after induction of hypotension. Materials and methods: A total of 40 pregnant SpragueDawley rats were subjected to either transient systemic hypotension produced for 30 min by blood withdrawal via femoral artery catheterization (hypotension group) or sham operation (control group) on day 15. Two randomly selected fetuses were taken from each rat at 0, 6, 12, and 24 h after the procedure. Apoptosis was evaluated in sections from the whole fetal brain by TUNEL and caspase-3 staining. …
Behavioural And Neurobiological Consequences Of 2 Different Chronic Stressors In Rats, Refi̇a Aslihan Dönmez, Fatma Duygu Kaya, Okşan Deri̇nöz, Ömer Hakan Emmez, Selçuk Candansayar, Hayrunni̇sa Bolay Belen
Behavioural And Neurobiological Consequences Of 2 Different Chronic Stressors In Rats, Refi̇a Aslihan Dönmez, Fatma Duygu Kaya, Okşan Deri̇nöz, Ömer Hakan Emmez, Selçuk Candansayar, Hayrunni̇sa Bolay Belen
Turkish Journal of Medical Sciences
To compare the behavioural and neurobiological consequences of chronic headache and chronic mild stress (CMS) in rats. Materials and methods: Forty-eight male Wistar rats were divided into 4 groups: 1) control group, 2) chronic headache group, 3) CMS group, and 4) sham group. Their behaviour prior to (D0) and after (D14) chronic stress was analysed. Afterwards, they were exposed to the Elevated Plus Maze (EPM) in order to evaluate anxiety-like behaviour and the Forced Swim Test (FST) for observation of depressive-like behaviour. Ultrasonic vocalisations (USVs) were recorded by a USV detector system at D0 and D14 and during the FST. …
Serum Fetuin-A Levels In Postmenopausal Women With Osteoporosis, Esi̇n Özkan, Hüseyi̇n Özkan, Serkan Bi̇lgi̇ç, Ersi̇n Odabaşi, Nuray Can, Emi̇n Özgür Akgül, İbrahi̇m Yanmiş, Yüksel Yurttaş, Mustafa Kürklü, Mustafa Başbozkurt, Mehmet Kemal Erbi̇l
Serum Fetuin-A Levels In Postmenopausal Women With Osteoporosis, Esi̇n Özkan, Hüseyi̇n Özkan, Serkan Bi̇lgi̇ç, Ersi̇n Odabaşi, Nuray Can, Emi̇n Özgür Akgül, İbrahi̇m Yanmiş, Yüksel Yurttaş, Mustafa Kürklü, Mustafa Başbozkurt, Mehmet Kemal Erbi̇l
Turkish Journal of Medical Sciences
One of the functions of fetuin-A is the restriction of formation and expansion of extraosseous hydroxyapatite crystals. The exact correlation of fetuin-A with bone mineral density (BMD) has not been clearly elucidated yet. In this study, we aimed to assess the relationship between BMD and fetuin-A in postmenopausal women. Materials and methods: Fifty postmenopausal women (25 with osteoporosis, 25 healthy controls) were included in the study. All participants were comparable for age and body mass index. None of the osteoporotic patients had received any medical treatment for osteoporosis. Serum fetuin-A levels were measured by ELISA method. Results: BMD scores of …
Possible Metabolic Impact Of Ramadan Fasting In Healthy Men, Mustafa Cumhur Vardarli, Hans-Peter Hammes, İrfan Vardarli
Possible Metabolic Impact Of Ramadan Fasting In Healthy Men, Mustafa Cumhur Vardarli, Hans-Peter Hammes, İrfan Vardarli
Turkish Journal of Medical Sciences
Insulin sensitivity and \beta-cell function during Ramadan fasting in healthy male subjects have not been investigated so far. We assessed the changes of these and other metabolic parameters to judge the potential metabolic benefits of Ramadan fasting. Materials and methods: Twenty-four healthy males of Turkish origin living in Germany, with normal glucose tolerance, participated in this study during Ramadan of 2009; 19 who completed fasting were analyzed. Blood was drawn at sunset after a period of fasting lasting approximately 15 h on days 0, 16, and 30 of Ramadan, as well as 7 and 28 days later. Insulin sensitivity (Homeostasis …
Evaluation Of Scleral-Fixated Intraocular Lens Position Anomalies By Anterior Segment Optical Coherence Tomography, Ni̇hat Polat, Kemaletti̇n Kazim Devranoğlu, Mehmet Aki̇f Özdamar, Ceyhun Arici
Evaluation Of Scleral-Fixated Intraocular Lens Position Anomalies By Anterior Segment Optical Coherence Tomography, Ni̇hat Polat, Kemaletti̇n Kazim Devranoğlu, Mehmet Aki̇f Özdamar, Ceyhun Arici
Turkish Journal of Medical Sciences
To measure the positions of scleral-fixated intraocular lenses (IOLs) using anterior segment optical coherence tomography (OCT) and to evaluate the influence of the position of scleral-fixated IOL on the quality of vision. Materials and methods: Twenty-six eyes of 26 patients were included in the study. The average age was 57.5 (11 to 78) years. Anterior segment images were taken using slit lamp optical coherence tomography (SL-OCT) and were used to evaluate the position of the IOL. Results: The average amounts of tilt and decentration were 2.25° ± 1.93° and 359.28 ± 194.70 µm, respectively. There was a positive and moderate …
Prohepcidin In Maternal Circulation: Is It Related To Spontaneous Preterm Labor?, Yüksel Onaran, Esra Aktepe Keski̇n, Zehra Candan İltemi̇r Duvan, Serap Aynur Si̇mavli, Cemi̇le Koca, Hasan Kafali, Ni̇lgün Turhan
Prohepcidin In Maternal Circulation: Is It Related To Spontaneous Preterm Labor?, Yüksel Onaran, Esra Aktepe Keski̇n, Zehra Candan İltemi̇r Duvan, Serap Aynur Si̇mavli, Cemi̇le Koca, Hasan Kafali, Ni̇lgün Turhan
Turkish Journal of Medical Sciences
To investigate whether spontaneous preterm labor (PTL) with intact membranes is associated with changes in maternal serum prohepcidin concentrations. Materials and methods: The study consisted of patients with spontaneous PTL with intact membranes (n = 25), a control group of healthy pregnant women between the 24th and 37th gestational weeks (n = 22), and uncomplicated term pregnancies in spontaneous labor (n = 19). Blood samples were collected from patients at the time of clinical diagnosis. Levels of prohepcidin, hemoglobin, serum ferritin, serum iron, unsaturated iron binding capacity, total iron binding capacity, transferrin and transferrin saturation, C reactive protein, and interleukin-6 …
The Diagnostic Efficiency Of Ct And Mri In Ileosigmoid Knotting, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bülent Aydinli, Gürkan Öztürk, Şükrü Arslan, Ercan Korkut, Metehan Gümüş, Abdullah Böyük
The Diagnostic Efficiency Of Ct And Mri In Ileosigmoid Knotting, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bülent Aydinli, Gürkan Öztürk, Şükrü Arslan, Ercan Korkut, Metehan Gümüş, Abdullah Böyük
Turkish Journal of Medical Sciences
No abstract provided.
Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k
Distal Radius Measurements And Efficacy Of Fixed-Angle Locking Volar Plates, İsmai̇l Ağir, Mahmut Nedi̇m Ayteki̇n, Fati̇h Küçükdurmaz, Onur Başci, Ci̇hangi̇r Teti̇k
Turkish Journal of Medical Sciences
For surgical treatment of unstable distal radius fractures, fixed-angled locking volar plate fixation is becoming popular nowadays because of some advantages over other surgical techniques. In this article, we discuss the fitting of fixed-angle locking volar plates to the distal radius in relation to the changes in the distal radial angles. Materials and methods: First, we took conventional radiography images of 18 dried radii and later we measured the palmar subchondral angle, dorsal subchondral angle, mid-subchondral angle, and palmar cortical angle using lateral radiography. Results: According to the measurements, the volar subchondral angles (alpha) ranged from 10.2° to 28.1°, the …
Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r
Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r
Turkish Journal of Medical Sciences
To analyze the phenolic composition of the Cimin grape, which is 1 of 2 grape varieties with a protected geographical indication in Turkey and is used locally to treat the symptoms of some disorders such as impotence and cardiovascular diseases, and to investigate its antioxidant potency against oxidant mediators in the models of intra- and extracellular surroundings. Materials and methods: Cimin grape samples were classified into 5 groups according to the grape's tissues and the extraction solvents used. Free radical scavenging (DPPH) and antilipid peroxidation product [thiobarbituric acid reactive substance (TBARS) and conjugated diene (CD)] levels of the grape tissues …
Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural
Single Port Thoracoscopic Sympathectomy For Primary Palmar Hyperhidrosis In Adolescence, Nesi̇mi̇ Günal, Berkant Özpolat, Yasemi̇n Dere Günal, Koray Dural
Turkish Journal of Medical Sciences
Hyperhidrosis is defined as excessive sweating beyond the physiologic needs of a person. Palmar hyperhidrosis in the adolescent period may have an impact on school work and may cause psychological problems. In this study we aim to increase awareness of this disregarded problem. Materials and methods: We explicated the early outcomes of 7 consecutive adolescents, where single port video-assisted thoracoscopic sympathectomy was performed for primary palmar hyperhidrosis. Patients were evaluated for symptom resolution, which was defined as complete dryness, patient satisfaction, operative complications, and compensatory sweating. Results: In total 13 thoracoscopic procedures were done in 7 adolescents, consisting of 4 …
Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k
Is Perioperative Examination Of Frozen Sections Necessary In Nephron-Sparing Surgery?, Mehmet Kalkan, Soner Yalçinkaya, Coşkun Şahi̇n, Yeşi̇m Üçkurt, Ömer Etli̇k
Turkish Journal of Medical Sciences
To evaluate the role of perioperative freezing in the management of surgical procedures in patients with malignant renal masses. Materials and methods: The study group consisted of 17 patients diagnosed with renal masses who underwent nephron-sparing surgery. The group included 5 females and 12 males aged from 44 to 68 years (mean = 54.6). The mean mass size was 5.5 cm. Mass locations were as follows: 9 were in the lower pole, 4 were in the mid-pole, and 6 were in the upper pole. Perioperative freezing was not carried out. The patients were followed-up in a period ranging from 3 …
Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp
Protective Role Of Caffeic Acid Phenethyl Ester On Serum Cholinesterase Inhibition By Acute Exposure To Diazinon In Rats, Esi̇n Oğuzhanoğlu, Ahmet Cenk Andaç, Adnan Tüfek, Lütfi̇ Yavuz, Hüseyi̇n Vural, Osman Gökalp
Turkish Journal of Medical Sciences
To evaluate whether caffeic acid phenethyl ester (CAPE), a flavonoid-like natural compound plentifully found in beeswax, has a protective effect on diazinon-induced serum cholinesterase (ChE) inhibition in rats. Materials and methods: Animals were divided into 4 groups. The first animal group was not treated with any substance. The second animal group was orally given a 200 mg/kg body weight (bw) sublethal dose of diazinon. The third animal group was injected intraperitoneally with 2.84 mg (10 µmol)/kg bw of CAPE 1 day prior to administration of 200 mg/kg bw of diazinon orally. The fourth animal group was intraperitoneally injected with 2.84 …
Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu
Evaluation Of Outer Hair Cell Function And Medial Olivocochlear Efferent System In Patients With Type Ii Diabetes Mellitus, Hayri̇ye Karabulut, İsmai̇l Karabulut, Muharrem Dağli, Yildirim Ahmet Bayazit, Şule Bi̇len, Yusuf Aydin, Serdar Güler, İsmet Bayramoğlu
Turkish Journal of Medical Sciences
This study was designed to investigate the function of outer hair cells and medial olivocochlear efferents in type II diabetes mellitus (DM). Materials and methods: There were 50 patients with type II DM and 51 age- and sex-matched healthy controls included in the study. Both groups were compared in terms of transient evoked otoacoustic emissions (TEOAEs), distortion product otoacoustic emissions (DPOAEs), and contralateral suppression of TEOAE. Results: Pure tone thresholds of the patients with type II DM were significantly higher than in the controls (P < 0.05). The TEOAE amplitudes at 1 kHz and at 1.5, 2, 3, 4, and 6 kHz signal-to-noise ratio amplitudes on DPOAE testing were significantly lower in the patients than controls (P < 0.05). There was no significant difference between the type II DM and control groups regarding contralateral suppression test results of TEOAEs. Conclusion: Type II DM seems to impact the auditory system at the cochlear level by affecting the functions of outer hair cells, and it results in elevation of the thresholds on audiometry and a decrease in the amplitudes of otoacoustic emissions.
Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak
Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak
Turkish Journal of Medical Sciences
This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning …
Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
To analyze patients with Castleman disease who were diagnosed by surgery. Materials and methods: We retrospectively investigated the postoperative pathological records of operations performed between January 1992 and December 2012 in our hospital. Files of 19 patients with the diagnosis of Castleman disease were analyzed. Results: There were 13 male and 6 female patients with a mean age of 40.1 ± 11.4 (range: 20-57) years. Fifteen thoracotomies and 3 video-assisted thoracoscopies, 12 on the right side and 6 on the left side, and 1 mediastinoscopy were performed. Biopsies and mass excisions were performed in 2 and 17 cases, respectively. Histopathological …
Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇
Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇
Turkish Journal of Medical Sciences
To define the frequency of familial Mediterranean fever gene (MEFV) mutations in ankylosing spondylitis (AS) and describe different clinical aspects of MEFV mutation carrier and noncarrier AS patients. Materials and methods: In 112 AS patients, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores were calculated. The frequencies of 12 different MEFV mutations were studied by multiplex polymerase chain reaction/reverse hybridization method and were compared to those of previously studied healthy controls for 5 common MEFV mutations. Results: MEFV mutations were identified in 46 of 224 (20%) alleles and in 39 (35%) of AS …
Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay
Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay
Turkish Journal of Medical Sciences
To evaluate the effectiveness of the addition of epirubicin to conventional chemotherapy as a first-line therapy for stage III–IV epithelial ovarian cancer. Materials and methods: A total of 132 patients who had undergone primary cytoreductive surgery between January 1998 and March 2003 were enrolled in the study. Twenty-four cases were excluded. Out of the remaining 108 subjects, 35 received epirubicin/paclitaxel/carboplatin (Group EPC) and 73 were treated with paclitaxel/platinum (cisplatin or carboplatin) (Group PC). Results: The median follow-up period was 66.5 months. The clinical complete response was 94% in the EPC group and 97% in the PC group. The recurrence rate …
Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu
Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu
Turkish Journal of Medical Sciences
To carry out comparison and correlation analyses of the intervertebral disc (IVD) and vertebral body (VB) volumes in magnetic resonance (MR) images of patients with degenerated and nondegenerated lumbar discs. Materials and methods: MR images were examined retrospectively in 93 patients. Lumbar VB and IVD volumes in T1-T2 weighted sagittal MR images were calculated via the Cavalieri method, a stereological method. Volumetric changes in degenerated and nondegenerated discs were compared. Results: The percentages of degenerated IVDs were 12.9%, 12.9%, 28%, 50.5%, and 52% in discs from levels L1 to L5, respectively. There were no differences in VB volumes between the …
The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan
The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan
Turkish Journal of Medical Sciences
To evaluate the prevalence of nocturia among different degrees of obstructive sleep apnea (OSA) and its association with various clinical conditions. Materials and methods: In 730 OSA patients, the prevalence and frequency of nocturia was determined, and the association of nocturia with clinical and laboratory variables such as the apnea-hypopnea index (AHI), apnea duration, and minimum oxygen saturation and clinical conditions such as diabetes mellitus, coronary heart disease, and chronic obstructive pulmonary disease (COPD) was determined. Results: The overall prevalence of nocturia (>=2 wakes/night) was 50.9%. Prevalences of nocturia in simple snoring and mild, moderate, and severe OSA patients …
New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu
New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu
Turkish Journal of Medical Sciences
To conduct a histopathological evaluation of the effects of Ankaferd Blood Stopper (ABS) on healing wounds in a rabbit skin incision model. Materials and methods: Incisions were performed on the backs of rabbits. The first incision was allowed to undergo normal secondary healing. ABS (1 mL) was applied to the second incision, which was subsequently allowed to undergo secondary healing. The third incision was sutured. ABS (1 mL) was applied to the fourth incision, which was subsequently sutured. During the wound healing period, the histopathologic signs of ulceration, inflammation, the proliferative phase, and the extent of early remodeling were comparatively …
Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk
Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk
Turkish Journal of Medical Sciences
To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. Materials and methods: The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease were noted. Results: The mean age at presentation was 36.23 ± 14.9 years. Males constituted 58.2% of patients. Anatomically, anterior uveitis (42%) was most common, followed by posterior uveitis (24.9%), panuveitis (24.7%), and intermediate uveitis (8.4%). The course of the disease was mostly chronic (65.7%). The …
The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp
The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp
Turkish Journal of Medical Sciences
Letter to the Editor
Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar
Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar
Turkish Journal of Medical Sciences
Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates. The onset is commonly insidious and the poor prognosis is attributed to the long delay in diagnosis. Unfortunately, diagnosis is often delayed until loss of function in the affected tissues has already occurred. The aim of this study was to determine the predictive value of mean platelet volume (MPV) in assessing the risk of intraabdominal hypertension. Materials and methods: Pneumoperitoneum during elective laparoscopic cholecystectomy was used as a model for intraabdominal hypertension. The study included 103 patients who met the …
Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur
Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur
Turkish Journal of Medical Sciences
To determine the overall and comparative incidence of refeeding hypophosphatemia (RH) between enteral and parenteral nutrition in general adult intensive care unit (ICU) patients. Materials and methods: This study was performed as a retrospective analysis. A total of 117 patients who received enteral and parenteral nutrition were included in the study. Demographic characteristics, type of nutrition, daily energy intake, and serum phosphorus levels before and after the initiation of the nutrition were recorded for 7 days. Results: The mean age of the patients was 65.8 ± 16.7 years. RH was found in 61 patients (52.14%). There was no significant difference …
The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren
The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren
Turkish Journal of Medical Sciences
Anesthesiologists have encountered various difficulties in securing the airway. Therefore, we compare the intubation times and hemodynamic changes between the McGrath Series 5 video laryngoscope and the Macintosh laryngoscope. Materials and methods: A total of 80 obstetric patients were divided into 2 groups, orotracheally intubated with either the McGrath video laryngoscope or the Macintosh laryngoscope. The intubation times, Cormack-Lehane grade, percentage of glottic opening, mean arterial blood pressure, and heart rates were compared among the groups. Results: Intubation time in the McGrath video laryngoscope group was significantly longer than in the Macintosh laryngoscope group (P < 0.01). The percentage of glottic opening was found to be higher in the McGrath video laryngoscope group (P = 0.002). Conclusion: The McGrath Series 5 video laryngoscope provides excellent views during orotracheal intubation in obstetric anesthesia with normal airways.
The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek
The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek
Turkish Journal of Medical Sciences
Ventriculoperitoneal shunt infections remain an important problem and result mainly from perioperative colonization of shunt components by skin flora. Antibiotic-impregnated shunts have been designed to prevent such colonization. This study evaluates the incidence of shunt infection after the insertion of antibiotic-impregnated shunts in a population of children with hydrocephalus. Materials and methods: All pediatric patients who had undergone cerebrospinal fluid shunt insertion retrospectively were reviewed over a 6-year period between May 2004 and December 2010. The primary outcome measure was the rate of shunt infections. Patients were followed up with for an average of 26.2 months after shunt surgery, and …