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Full-Text Articles in Medicine and Health Sciences

Clinical And Radiographic Characterization Of Xenotransplantation Of Rat Bonemarrow-Derived Mesenchymal Stem Cells For Repair Of Radial Defects Of Rabbit, Betania Monteiro, Lukiya Favarato, Pablo Carvalho, Barbara Okano, Maria Antonia Menegatti, Alvaro Oliveira, Bianka Santos, Ricardo Del Carlo Jan 2015

Clinical And Radiographic Characterization Of Xenotransplantation Of Rat Bonemarrow-Derived Mesenchymal Stem Cells For Repair Of Radial Defects Of Rabbit, Betania Monteiro, Lukiya Favarato, Pablo Carvalho, Barbara Okano, Maria Antonia Menegatti, Alvaro Oliveira, Bianka Santos, Ricardo Del Carlo

Turkish Journal of Veterinary & Animal Sciences

This study aimed to evaluate the clinical and radiographic aspects of xenogenic transplantation of rat bone marrow-derived mesenchymal stem cells (MSCs) for the repair of radial bone defects of rabbit. Bone marrow derived MSCs collected from Wistar rats were expanded, differentiated, and labeled in the laboratory. In the fourth passage, the cultures were pelleted in aliquots of 107 cells/50 μL and transplanted in situ into the lesions. Thirty-six rabbits were used in the in vivo study. In all animals, defects were created by removing a bone segment of 1.0 cm in length in the right radius. The rabbits were divided …


A Novel Approach For Determination Of Chicken Sexing At An Early Stage Of Development By Using Loop-Mediated Isothermal Amplification Method, Sung Woo Kim, Jin Seok Choi, Neelesh Sharma, Yeoung Gyu Ko, Yoon Jung Do, Mijeong Byun, Hwan Hoo Seong, Soo Bong Park, Dong Kee Jeong Jan 2015

A Novel Approach For Determination Of Chicken Sexing At An Early Stage Of Development By Using Loop-Mediated Isothermal Amplification Method, Sung Woo Kim, Jin Seok Choi, Neelesh Sharma, Yeoung Gyu Ko, Yoon Jung Do, Mijeong Byun, Hwan Hoo Seong, Soo Bong Park, Dong Kee Jeong

Turkish Journal of Veterinary & Animal Sciences

The monomorphism of newly hatched chicks is a major hurdle for poultry farmers at the time of sexing. The traditional sexing techniques are inaccurate and time-consuming. Therefore, the present study aimed to develop a loop-mediated isothermal amplification (LAMP)-based sex determination method to obtain a higher separation accuracy rate as compared to conventional methods. LAMP is a simple, quick, and relatively inexpensive diagnostic tool. Genomic DNA was extracted from the blood samples of Leghorn and Korean native chicks for LAMP. Two sets of primer were designed, consisting of four isothermal amplification primers in each, to amplify the female sex-specific sequence (HUR0417) …


Prevalence Of Blaz Gene And Other Virulence Genes In Penicillin-Resistant Staphylococcus Aureus Isolated From Bovine Mastitis Cases In Gansu, China, Feng Yang, Qi Wang, Xurong Wang, Ling Wang, Min Xiao, Xinpu Li, Jinyin Luo, Shidong Zhang, Hongsheng Li Jan 2015

Prevalence Of Blaz Gene And Other Virulence Genes In Penicillin-Resistant Staphylococcus Aureus Isolated From Bovine Mastitis Cases In Gansu, China, Feng Yang, Qi Wang, Xurong Wang, Ling Wang, Min Xiao, Xinpu Li, Jinyin Luo, Shidong Zhang, Hongsheng Li

Turkish Journal of Veterinary & Animal Sciences

Staphylococcus aureus is a major etiological agent of bovine mastitis worldwide. In this study, 37 strains of S. Aureus resistant to penicillin were isolated from bovine mastitis cases in Gansu Province for investigating blaZ and virulence-related genes, including tst, eta, etb, lukPV, lukED, lukM, hla, hlb, hld, and edin. Antibiotic resistance was based on disk diffusion method and blaZ and virulence-associated genes were studied by polymerase chain reaction. Penicillin resistance gene blaZ was detected in 35/37 (94.6%) of penicillin-resistant S. Aureus isolates. tst, lukPV, lukED, hla, hlb, and hld were observed in 5.4%, 2.7%, 89.2%, 70.3%, 73.0%, and 70.3% of …


Significance Of Homocysteine And Cardiac Markers In Cattle With Hypocalcemia, Yildiray Başbuğan, Nazmi̇ Yüksek, Nuri̇ Altuğ Jan 2015

Significance Of Homocysteine And Cardiac Markers In Cattle With Hypocalcemia, Yildiray Başbuğan, Nazmi̇ Yüksek, Nuri̇ Altuğ

Turkish Journal of Veterinary & Animal Sciences

This study aimed to determine the levels of homocysteine and cardiac markers in cows with hypocalcemia. This research was conducted with a total of 20 cows, including 10 with hypocalcemia and 10 healthy controls. Hypocalcemia was diagnosed by determining low blood calcium (Ca) levels, and a standard hypocalcemia treatment was initiated in those cows with the disease. Blood samples were taken before the treatment and again 12 h after the treatment, and there was no significant difference in the homocysteine levels between the groups. Ca, ionized calcium (Ica), magnesium (Mg), and phosphorus (P) levels were lower, while cardiac troponin I …


The Effects Of Vincristine Sulfate On Expression Of Galectin-3, Bcl-2, And Carbohydrate Structures Specific For Eel, Gsl-1, And Rca-1 Lectins In Bitches With Naturally Occurring Canine Transmissible Venereal Tumor, Musa Özgür Özyi̇ği̇t, Deni̇z Nak, Hasan Akşi̇t, Sevda İnan Öztürkoğlu, Gözde Şi̇mşek, Ender Uzabaci, Yavuz Nak, Kami̇l Seyrek Jan 2014

The Effects Of Vincristine Sulfate On Expression Of Galectin-3, Bcl-2, And Carbohydrate Structures Specific For Eel, Gsl-1, And Rca-1 Lectins In Bitches With Naturally Occurring Canine Transmissible Venereal Tumor, Musa Özgür Özyi̇ği̇t, Deni̇z Nak, Hasan Akşi̇t, Sevda İnan Öztürkoğlu, Gözde Şi̇mşek, Ender Uzabaci, Yavuz Nak, Kami̇l Seyrek

Turkish Journal of Veterinary & Animal Sciences

Vincristine sulfate is one of the most effective chemical agents used in canine transmissible venereal tumor (CTVT) chemotherapy. Its therapeutic effectiveness is pronounced and significant at the beginning of treatment. The present study was designed to investigate vincristine sulfate treatment and the relationship between CTVT tumor regression and apoptosis [estimated by TdT-mediated dUTP-biotin nick end labeling (TUNEL)], galectin-3 (H-160), Bcl-2 (N-9), and lectin [EEL (B-135), GSL I (L-1100), and RCA I (BA-0084)] expression using immunohistochemical staining in 20 bitches with naturally occurring CTVTs. Evaluation was semiquantitatively performed by HSCORE values using light microscopy. All observed staining was intracytoplasmic and increased …


Urinary Tract Infection In Patients With Chronic Kidney Disease, Chih-Yen Hsiao, Hsing-Lin Lin, Yen-Ko Lin, Chao-Wen Chen, Yuan-Chia Cheng, Wei-Che Lee, Tzu-Chin Wu Jan 2014

Urinary Tract Infection In Patients With Chronic Kidney Disease, Chih-Yen Hsiao, Hsing-Lin Lin, Yen-Ko Lin, Chao-Wen Chen, Yuan-Chia Cheng, Wei-Che Lee, Tzu-Chin Wu

Turkish Journal of Medical Sciences

Chronic kidney disease (CKD) has become a burden of health care globally. However, data on epidemiology, clinical features, and outcomes of urinary tract infection (UTI) in this population are scarce. This study aims to retrospectively review such data. Materials and methods: A retrospective cohort study was conducted from 1 January 2005 to 31 December 2011 in patients with CKD requiring hospitalization. Patients who had upper and lower UTIs were compared for demography and clinical data. Logistic regression was used to assess which variables were associated with upper UTI. Results: A total of 276 bacteriuria patients were admitted to our ward …


Effects Of Infectious Bursal Disease (Ibd) On Shank Length And Diameter, Body Weight And Mortality In Broiler Breeder At Rearing Period, Ahmad Salahi, Mozhdeh Moosanezhad Khabisi, Ali Anissian Jan 2014

Effects Of Infectious Bursal Disease (Ibd) On Shank Length And Diameter, Body Weight And Mortality In Broiler Breeder At Rearing Period, Ahmad Salahi, Mozhdeh Moosanezhad Khabisi, Ali Anissian

Turkish Journal of Veterinary & Animal Sciences

Shank length is used as a tool for the determination of fertility, body weight, estimates of frame size, and the monitoring of growth and development of pullets. This study was carried out to investigate the effects of infectious bursal disease (IBD) on shank length, diameter, body weight, shank length and body weight growth curves, and mortality rate in males and females in the rearing period in broiler breeder flocks. In this study, 2 broiler breeder flocks (Ross 308 flocks) and 800 breeder chicks (both females and males) were selected for shank length and diameter assessments. All the management, nutrition, and …


Ultrasonographic Evaluation Of Massive Abdominal Wall Swellings In Cattle And Buffaloes, Ashwani Kumar, Jitender Mohindroo, Vandana Sangwan, Shashi Kant Mahajan, Kiranjeet Singh, Arun Anand, Narinder Singh Saini Jan 2014

Ultrasonographic Evaluation Of Massive Abdominal Wall Swellings In Cattle And Buffaloes, Ashwani Kumar, Jitender Mohindroo, Vandana Sangwan, Shashi Kant Mahajan, Kiranjeet Singh, Arun Anand, Narinder Singh Saini

Turkish Journal of Veterinary & Animal Sciences

Eight cows and 7 buffaloes with massive abdominal wall swellings were examined. The aim of the ultrasonographic study was to learn the contents of the abdominal wall swellings. They were divided into 4 groups: Group I (prepubic tendon rupture or hernia), Group II (fibrino-cystic swelling), Group III (abscess), and Group IV (inflammatory swelling). Palpation of the swelling in semidorsal recumbency, needle aspiration, or surgery was used to confirm the diagnosis. In animals of Groups I, II, and III, in the ultrasound, the muscles appeared to separate from the skin at the margin of swelling, thus creating a gap. In this …


Study On The Relationship Between Single Nucleotide Polymorphisms Of The Coccidiosis-Resistance Candidate Zyxin Gene Exon 1 And Carcass Traits In The Jinghai Yellow Chicken, Guojun Dai, Dahui Sun, Mingming Sun, Yuxin Lin, Xiang Wang, Genxi Zhang, Kaizhou Xie, Miaomiao Shi, Olajide Olowofeso, Jinyu Wang Jan 2014

Study On The Relationship Between Single Nucleotide Polymorphisms Of The Coccidiosis-Resistance Candidate Zyxin Gene Exon 1 And Carcass Traits In The Jinghai Yellow Chicken, Guojun Dai, Dahui Sun, Mingming Sun, Yuxin Lin, Xiang Wang, Genxi Zhang, Kaizhou Xie, Miaomiao Shi, Olajide Olowofeso, Jinyu Wang

Turkish Journal of Veterinary & Animal Sciences

Previous research revealed that several single nucleotide polymorphisms (SNPs) of zyxin were significantly associated with coccidiosis-resistance parameters. In this research, the Jinghai yellow chicken was chosen to detect the SNPs of zyxin gene exon 1 by PCR-SSCP and DNA sequencing techniques, and was also used to analyze the effect of zyxin SNPs on carcass traits. A single mutation was found with 3 genotypes, designated as AA, AB, and BB. The results showed that BB was significantly different from AA and AB in terms of abdominal fat weight and slaughter rate for cockerel (P < 0.05), while there was no significant difference between AA and AB (P > 0.05). The heart weight, breast muscle rate, …


Attachment Style And Perceived Social Support As Predictors Of Biopsychosocial Adjustment To Cancer, Ayşe Gül Yilmaz Özpolat, Tuğba Ayaz, Özlem Konağ, Asi̇ye Özkan Jan 2014

Attachment Style And Perceived Social Support As Predictors Of Biopsychosocial Adjustment To Cancer, Ayşe Gül Yilmaz Özpolat, Tuğba Ayaz, Özlem Konağ, Asi̇ye Özkan

Turkish Journal of Medical Sciences

Social support is associated with a decrease in psychological symptoms and a better quality of life in cancer patients. The aim of this study was to investigate the role of attachment dimensions on social and psychological adjustment to cancer and to explore the social and psychological adjustments, and medical adherence, among patients. Materials and methods: The study was conducted with 68 cancer patients, between 18 and 74 years of age. The measures taken were the Demographic Information Form, Multidimensional Scale of Perceived Social Support (MSPSS), Experiences in Close Relationships-Revised (ECR-R), and Psychosocial Adjustment to Illness Scale (PAIS-SR). Results: The results …


Effects Of Short-Term Hyperglycemia On The Vasoconstriction Of The Aorta, Soner Dönmez, Osman Gökalp, Mustafa Doğan, Hüseyi̇n Vural, Barbaros Yi̇ği̇t Jan 2014

Effects Of Short-Term Hyperglycemia On The Vasoconstriction Of The Aorta, Soner Dönmez, Osman Gökalp, Mustafa Doğan, Hüseyi̇n Vural, Barbaros Yi̇ği̇t

Turkish Journal of Medical Sciences

To investigate vasoconstrictor responses of healthy blood vessels to short-term hyperglycemic conditions such as postprandial hyperglycemia, gestational diabetes mellitus, and steroid-induced diabetes. Materials and methods: Female Wistar rat aorta rings were incubated in normal (11 mM) and high (22 mM and 44 mM) glucose concentrations for 4 h. Responses of vasoconstriction were measured in reaction to serotonin (10-5 M), phenylephrine (10-6 M), and KCl (60 mM) compared to the ambient condition, including different glucose concentrations. Results: While the responses of vasoconstriction to KCl were increased in the presence of Krebs' solution with high glucose, no statistically significant changes were observed …


Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak Jan 2014

Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak

Turkish Journal of Medical Sciences

To determine the levels of adipokines (leptin, adiponectin, resistin, and visfatin) and the indices of insulin sensitivity/resistance, and to examine the relationship among them in patients with metabolic syndrome (MetS). Materials and methods: The study groups included 45 subjects with MetS (31 women/14 men), and 45 sex-and age-matched non-MetS healthy volunteers (31 women/14 men). The levels of adipokines were determined by enzyme-linked immunosorbent assay. Results: The levels of leptin and visfatin were significantly higher in the MetS than in the non-MetS subjects (P < 0.01). There was no difference in adiponectin levels in subjects with and without MetS (P = 0.052). Similarly, resistin did not show any statistically significant difference. A statistically significant positive correlation of leptin with insulin levels was observed, while negative correlations of visfatin levels with age, and resistin levels with the ratio of adiponectin to leptin, were found in the MetS (P < 0.05). The combination of adipokines, insulin resistance-sensitivity parameters, and MetS criteria parameters gave more significant differences than a single parameter. Conclusion: Since the parameters mentioned above might affect, interact with, and/or interfere with each other, the combinations of these parameters might give more reliable results to evaluate the insulin resistance/sensitivity in MetS patients.


The Treatment Of Congenitally Developed Fused Vulva Labia In A Brown-Swiss Heifer, Oktay Yilmaz, Ebubeki̇r Yazici, Mehmet Uçar, Muhammed Kürşad Bi̇rdane Jan 2014

The Treatment Of Congenitally Developed Fused Vulva Labia In A Brown-Swiss Heifer, Oktay Yilmaz, Ebubeki̇r Yazici, Mehmet Uçar, Muhammed Kürşad Bi̇rdane

Turkish Journal of Veterinary & Animal Sciences

A case of congenitally developed fused labia in a 13-month-old Brown-Swiss heifer, an uncommon entity, is described. On gross appearance of vulva, it was observed that there were only 2 small openings in the dorsal and ventral vulvar commissures. Ultrasonography of the genital tract revealed the presence of left and right ovaries, uterine horns, and cervix uteri. The abnormality of the vulva was surgically corrected. The heifer was synchronized and artificially inseminated postsurgically. During delivery, no complication was observed and a healthy male calf was born. To the authors' knowledge, this is the first report describing both the surgical treatment …


The Relationship Between Seropositivity And Tissue Cysts In Sheep Naturally Infected With Toxoplasma Gondii, Kader Yildiz, Oğuz Kul, Sami̇ Gökpinar, Hasan Tarik Atmaca, Yilmaz Emre Gençay, Aycan Nuri̇ye Gazyağci, Cahi̇t Babür, İsmayi̇l Safa Gürcan Jan 2014

The Relationship Between Seropositivity And Tissue Cysts In Sheep Naturally Infected With Toxoplasma Gondii, Kader Yildiz, Oğuz Kul, Sami̇ Gökpinar, Hasan Tarik Atmaca, Yilmaz Emre Gençay, Aycan Nuri̇ye Gazyağci, Cahi̇t Babür, İsmayi̇l Safa Gürcan

Turkish Journal of Veterinary & Animal Sciences

Skeletal muscles (tongue, masseter, leg, intercostal, and diaphragmatic muscles) and brain samples of 100 sheep at slaughter were analysed for the presence of T. gondii tissue cysts along with serum IgG titres. Two methods of isolation by percoll gradient centrifugation and tissue microarray (TMA) technique with immunoperoxidase staining were used. Seropositivity was detected in 88% (88/100) of sheep sera analysed by indirect fluorescent antibody test. Tissue cysts were observed in 46 (52.3%, 46/88) and 15 (17%, 15/88) of the seropositive sheep with the isolation technique and TMA and immunoperoxidase staining, respectively. The diameters of the tissue cysts were 25–58 × …


Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar Jan 2014

Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar

Turkish Journal of Medical Sciences

Both bupivacaine and levobupivacaine are local anesthetics with strong analgesic efficacy that can be used intraarticularly. The aim of this study was to compare the effects of intraarticular bupivacaine and levobupivacaine injection on inflammation in articular cartilage and the synovium of the rat knee joint. Materials and methods: Twenty Sprague-Dawley rats were injected in the right knee joint with 0.2 mL of bupivacaine, while 0.2 mL of levobupivacaine was injected into the left knee joint. Groups of 5 were sacrificed on days 1, 7, 14, and 21 after bupivacaine and levobupivacaine administration and knee joints were examined for subintimal fibrosis, …


Effect Of Ginkgo Biloba On Brain Volume After Carotid Artery Occlusion In Rats: A Stereological And Histopathological Study, Zeynep Aktürk, Ersan Odaci, Ayşe İki̇nci̇, Orhan Baş, Si̇nan Canpolat, Serdar Çolakoğlu, Osman Fi̇kret Sönmez Jan 2014

Effect Of Ginkgo Biloba On Brain Volume After Carotid Artery Occlusion In Rats: A Stereological And Histopathological Study, Zeynep Aktürk, Ersan Odaci, Ayşe İki̇nci̇, Orhan Baş, Si̇nan Canpolat, Serdar Çolakoğlu, Osman Fi̇kret Sönmez

Turkish Journal of Medical Sciences

This study investigated the effect of Ginkgo biloba (GB) on brain volume in cerebral ischemia induced by stopping carotid artery blood flow. Materials and methods: Twenty-four adult male rats were divided into 4 groups of 6 rats each. No procedure was performed on the control group. Ischemia was applied to the rats in the ischemia and ischemia + GB groups by clamping the arteria carotis communis for 30 min. The rats in the ischemia + GB group were given 100 mg/kg drops (Tebokan Fort Drop, Abdi İbrahim İlaç Sanayi A.Ş., Turkey) containing dry GB leaf extract orally, every day for …


Comparison Of Hippocampal Interleukin-6 Immunoreactivity After Exhaustive Exercise In Both Exercise-Trained And Untrained Rats, Lati̇fe Arzu Aral, Lamia Pinar, Güleser Göktaş, Elçi̇n Yaşar Deveden, Deni̇z Erdoğan Jan 2014

Comparison Of Hippocampal Interleukin-6 Immunoreactivity After Exhaustive Exercise In Both Exercise-Trained And Untrained Rats, Lati̇fe Arzu Aral, Lamia Pinar, Güleser Göktaş, Elçi̇n Yaşar Deveden, Deni̇z Erdoğan

Turkish Journal of Medical Sciences

Exhaustive exercise is a strong stress factor and can impact cytokine production in the brain. Interleukin-6 (IL-6) is produced in greater amounts than any other cytokine in response to exercise, and its effects are closely related to both exercise duration and intensity. In this study, we measured the differences between the amount of IL-6 reactivity of the hippocampus after an exhaustive session of running in long-term exercise-trained and untrained rats. Materials and methods: The exercise-trained group ran on a treadmill for 12 weeks. Both groups were forced to run until exhaustion. Each group of rats was sacrificed immediately, 1 day, …


The Role Of Hepcidin And Its Related Genes (Bmp6, Gdf-15, And Hjv) In Rats Exposed To Ischemia And Reperfusion, Recep Dokuyucu, Tuncer Demi̇r, Önder Yumrutaş, Ayşe Bi̇nnur Erbağci, Mustafa Örkmez, Abdulkadi̇r Yasi̇r Bahar, Recep Bayraktar, İbrahi̇m Bozgeyi̇k, Davut Si̇nan Kaplan, Beyhan Cengi̇z, Cahi̇t Bağci Jan 2014

The Role Of Hepcidin And Its Related Genes (Bmp6, Gdf-15, And Hjv) In Rats Exposed To Ischemia And Reperfusion, Recep Dokuyucu, Tuncer Demi̇r, Önder Yumrutaş, Ayşe Bi̇nnur Erbağci, Mustafa Örkmez, Abdulkadi̇r Yasi̇r Bahar, Recep Bayraktar, İbrahi̇m Bozgeyi̇k, Davut Si̇nan Kaplan, Beyhan Cengi̇z, Cahi̇t Bağci

Turkish Journal of Medical Sciences

To determine the roles of hepcidin and its related genes in a renal ischemia/reperfusion model. Materials and methods: A total of 20 Wistar albino rats were equally divided into 2 groups: Group I was the control group and Group II was the ischemia and reperfusion (I/R) group (60 min of ischemia + 48 h of reperfusion). I/R was performed on the left kidneys of these rats and then the I/R-treated kidneys were removed. The levels of serum biochemical markers were evaluated after renal I/R. The expression levels of hepcidin-linked genes [growth differentiation factor 15 (GDF-15), bone morphogenetic protein 6 (BMP6), …


Asymmetric Dimethyl Arginine Levels In Chronic Hemodialysis Patients, Aydin Çi̇fci̇, Sali̇h İnal, Coşkun Kaya Jan 2014

Asymmetric Dimethyl Arginine Levels In Chronic Hemodialysis Patients, Aydin Çi̇fci̇, Sali̇h İnal, Coşkun Kaya

Turkish Journal of Medical Sciences

To investigate serum asymmetric dimethyl arginine (ADMA) levels in maintenance hemodialysis (HD) patients and to assess their potential correlations with C-reactive protein (CRP), albumin, and cholesterol levels as the established cardiovascular and nutritional parameters. Materials and methods: Forty-nine patients on maintenance HD treatment and 22 healthy volunteers with similar age and sex characteristics were recruited into the study. Serum albumin, CRP, creatinine, calcium, phosphate, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, hemoglobin, white blood cell counts, and serum ADMA levels were measured. Results: HD patients had significantly higher ADMA levels compared with healthy controls (0.51 ± 0.25 …


Migraine Prevalence, Disability, And Sociodemographic Properties In The Eastern Region Of Turkey: A Population-Based Door-To-Door Survey, Gökhan Özdemi̇r, Recep Aygül, Recep Demi̇r, Lütfi̇ Özel, Ayfer Erteki̇n, Hizir Ulvi̇ Jan 2014

Migraine Prevalence, Disability, And Sociodemographic Properties In The Eastern Region Of Turkey: A Population-Based Door-To-Door Survey, Gökhan Özdemi̇r, Recep Aygül, Recep Demi̇r, Lütfi̇ Özel, Ayfer Erteki̇n, Hizir Ulvi̇

Turkish Journal of Medical Sciences

To determine the frequency of migraine in the eastern part of Turkey and its sociodemographic characteristics, impact on disability, and clinical aspects. Materials and methods: The study was conducted door-to-door in the eastern part of Turkey. Those who suffered from headaches were diagnosed with migraine as per the 2004 diagnosis criteria of the International Headache Society and its frequency was determined. Demographic data and Migraine Disability Assessment Scale (MIDAS) scores were recorded. Results: Of the individuals evaluated, 60.4% (883) suffered from headaches, of which 43.6% (637) were evaluated as nonmigraine and 16.8% (246) as migraine headaches. Migraine prevalence was detected …


Genotype Distribution Of Hepatitis C Virus In Khorasan Razavi Province, Iran, Reza Afshari, Hosein Nomani, Fatemeh Riyahi Zaniani, Maryam Sadat Nabavinia, Zohreh Mirbagheri, Mojtaba Meshkat, Sina Gerayli, Sina Rostami, Zahra Meshkat Jan 2014

Genotype Distribution Of Hepatitis C Virus In Khorasan Razavi Province, Iran, Reza Afshari, Hosein Nomani, Fatemeh Riyahi Zaniani, Maryam Sadat Nabavinia, Zohreh Mirbagheri, Mojtaba Meshkat, Sina Gerayli, Sina Rostami, Zahra Meshkat

Turkish Journal of Medical Sciences

Several types of the hepatitis C virus (HCV), with variations in different parts of the genome, have been isolated from different regions of the world. Based on heterogenic sequences in the isolated genome, HCV is classified into different genotypes and subtypes. Data on distribution of HCV genotypes in a certain region could be important to patient management. Therefore, this study was conducted to determine the distribution of HCV in Mashhad, Northeast Iran. Materials and methods: This cross-sectional study was conducted on 103 patients with HCV infections in Mashhad. Among the participants, at least 22 (21.4%) were intravenous drug users. HCV …


Transradial Approach In The Diagnosis And Treatment Of Coronary Artery Disease: A 2-Center Experience, Mustafa Yurtdaş, Yüksel Kaya, Edi̇p Gönüllü Jan 2014

Transradial Approach In The Diagnosis And Treatment Of Coronary Artery Disease: A 2-Center Experience, Mustafa Yurtdaş, Yüksel Kaya, Edi̇p Gönüllü

Turkish Journal of Medical Sciences

To document the safety, success, and complications of transradial coronary procedures. Materials and methods: This retrospective study consisted of 427 patients who had undergone transradial coronary angiography and/or angioplasty between June 2010 and May 2012. The main outcome measures were the procedural safety, success rate, and complications associated with transradial interventions. Results: Procedural success rate was 93.2% (398/427), with cannulation time of 2.1 ± 1.4 min, diagnostic time of 5.6 ± 2.1 min, fluoroscopy time of 9.5 ± 6.6 min, and total procedure time of 47.1 ± 20.2 min. The main causes for unsuccessful procedures were failed radial puncture (11 …


Seasonal Variation And Risk Factors Associated With Surgical Site Infection Rate In Kano, Nigeria, Emmanuel Nwankwo, Stephen Edino Jan 2014

Seasonal Variation And Risk Factors Associated With Surgical Site Infection Rate In Kano, Nigeria, Emmanuel Nwankwo, Stephen Edino

Turkish Journal of Medical Sciences

To evaluate the seasonal variations and risk factors associated with surgical site infection (SSI) rate in Kano. Materials and methods: A total of 5800 patients admitted for surgery, drawn from Aminu Kano Teaching Hospital and Murtala Mohammed Specialist Hospital, underwent different types of surgical procedures between January 2010 and December 2011. Out of those patients, 1463 confirmed infected cases were screened for bacterial and fungal infection by standard microbiological procedures. Questionnaires were administered after informed consent to ascertain patients' lifestyles. Medical histories were obtained from their case files. Results: Out of 5800 patients, 1463 were confirmed to be clinically infected, …


Age-Related Changes In Biomechanical Parameters Of The Cornea And Intraocular Pressure In A Healthy Turkish Population, Emi̇ne Şen, Kadri̇ye Ufuk Elgi̇n, Pinar Yüksekkaya, Mehmet Hakan Tirhiş, Fatma Nur Baran Aksakal, Mehmet Yasi̇n Teke, Faruk Öztürk Jan 2014

Age-Related Changes In Biomechanical Parameters Of The Cornea And Intraocular Pressure In A Healthy Turkish Population, Emi̇ne Şen, Kadri̇ye Ufuk Elgi̇n, Pinar Yüksekkaya, Mehmet Hakan Tirhiş, Fatma Nur Baran Aksakal, Mehmet Yasi̇n Teke, Faruk Öztürk

Turkish Journal of Medical Sciences

To investigate age-related changes in intraocular pressure (IOP) and biomechanical parameters of the cornea in healthy subjects. Materials and methods: There were 404 healthy subjects included prospectively in this study. The subjects were divided into 3 groups (Group 1: 93 subjects aged 60). Corneal compensated IOP (IOPcc), Goldmann correlated IOP (IOPg), corneal hysteresis (CH), and corneal resistance factor (CRF) were measured by the Ocular Response Analyzer. Results: When all the study groups were evaluated, a moderately significant negative correlation was found between age and CH and between age and CRF (Spearman's rho = -0.372 and -0.353, respectively; P < 0.0001 for both correlations). There were significant age-related differences among the 3 groups in terms of IOPg, CH, CRF, and central corneal thickness (P = 0.002, P = 0.000, P = 0.000, P = 0.006). There was no confirmation of any difference of IOPcc among the groups (P = 0.427). Conclusion: The mean values of IOPg, CH, and CRF were lower than the other parameters in Group 3 but no significant differences were determined in IOPcc values in the age groups.


Effects Of Some Of The Regional Turkish Fermented Foods And Medications On Respiratory Alcohol Levels, Cem Uysal, Mustafa Karapi̇rli̇, Mehmet Aki̇f İnanici Jan 2014

Effects Of Some Of The Regional Turkish Fermented Foods And Medications On Respiratory Alcohol Levels, Cem Uysal, Mustafa Karapi̇rli̇, Mehmet Aki̇f İnanici

Turkish Journal of Medical Sciences

Alcohols are used in many areas like medicine and industry. They may be naturally found in some fruits and vegetables secondary to fermentation. According to the traffic law in Turkey, professional drivers are prohibited from driving while they are under the influence of alcohol; nonprofessional drivers are allowed to drive vehicles with a blood alcohol level of up to 50 mg/dL. The aim of this research is to determine whether or not consumed medicine or fermented, nonalcoholic beverages cause false positive results in breathalyzer tests. Materials and methods: In this research, we used nonalcoholic fermented foods and 6 medicines. After …


Normal M Mode Values In Healthy Turkish Children, Bülent Oran, Abdurrahman Sai̇d Bodur, Derya Arslan, Derya Çi̇men, Osman Güvenç Jan 2014

Normal M Mode Values In Healthy Turkish Children, Bülent Oran, Abdurrahman Sai̇d Bodur, Derya Arslan, Derya Çi̇men, Osman Güvenç

Turkish Journal of Medical Sciences

Evaluation of cardiac structures requires a large study group for accurate data on normal values. The aim of the study was to obtain normal M mode echocardiographic values in a substantial sample of healthy term neonates and children to develop centile charts. Materials and methods: Data were obtained over 2 years from a single center in Turkey, from 1200 healthy infants and children aged 1 day to 17 years. Using echocardiographic investigation, measurements were obtained of the following: left ventricular dimension at end diastole and end systole; thickness of interventricular septum and posterior wall of the left ventricle; aortic and …


Is The Diagnosis And Treatment Of Childhood Acute Bacterial Meningitis In Turkey Evidence-Based?, Özden Türel, Mustafa Bakir Jan 2014

Is The Diagnosis And Treatment Of Childhood Acute Bacterial Meningitis In Turkey Evidence-Based?, Özden Türel, Mustafa Bakir

Turkish Journal of Medical Sciences

Evidence-based guidance is likely to significantly improve patient care. We aimed to characterize the adequacy of standard diagnostic methods and treatment in children with acute bacterial meningitis (ABM) in Turkey. Materials and methods: We conducted a retrospective study among children 1 month to 5 years old hospitalized with ABM in İstanbul. The World Health Organization case definition and laboratory criteria were used for diagnosis. Results: Of the 283 cases, 250 were probable and 33 (11.2%) were confirmed as bacterial meningitis. The majority of patients (92%) were treated at 9 governmental hospitals and the remaining 21 at 2 university hospitals. Blood …


Association Between The Apelin Rs2235306 Gene Polymorphism And Metabolic Syndrome, Mohammad Hashemi, Hamzeh Rezaei, Ebrahim Eskandari-Nasab, Mahmoud Ali Kaykhaei, Mohsen Taheri Jan 2014

Association Between The Apelin Rs2235306 Gene Polymorphism And Metabolic Syndrome, Mohammad Hashemi, Hamzeh Rezaei, Ebrahim Eskandari-Nasab, Mahmoud Ali Kaykhaei, Mohsen Taheri

Turkish Journal of Medical Sciences

The rs2235306 of apelin polymorphism has been shown to be associated with fasting plasma glucose levels and hypertension. The present study aimed to investigate the impact of the apelin rs2235306 gene polymorphism on the risk of metabolic syndrome (MeS) in a sample of the Iranian population. Materials and methods: This population-based cross-sectional study was performed on 151 subjects with MeS and 149 without MeS, as defined by ATPIII criteria. Apelin rs2235306 polymorphism detection was done using the tetra amplification refractory mutation system-polymerase chain reaction. Because the apelin gene is located on the X chromosome, statistical analyses were conducted in a …


Endothelial Dysfunction And Insulin Resistance In Young Women With Polycystic Ovarian Syndrome, Mi̇ne Yavuz Taşlipinar, Nedret Kiliç, Ni̇lüfer Bayraktar, İsmai̇l Güler, Yasemi̇n Gülcan Kurt, Tayfun Göktaş, Mehmet Zeki̇ Taner, Mehmet Özdemi̇r Hi̇mmetoğlu, Hali̇l Yaman, Abdullah Taşlipinar Jan 2014

Endothelial Dysfunction And Insulin Resistance In Young Women With Polycystic Ovarian Syndrome, Mi̇ne Yavuz Taşlipinar, Nedret Kiliç, Ni̇lüfer Bayraktar, İsmai̇l Güler, Yasemi̇n Gülcan Kurt, Tayfun Göktaş, Mehmet Zeki̇ Taner, Mehmet Özdemi̇r Hi̇mmetoğlu, Hali̇l Yaman, Abdullah Taşlipinar

Turkish Journal of Medical Sciences

To evaluate whether there is a correlation between insulin resistance and nitric oxide-related endothelial dysfunction in patients with polycystic ovarian syndrome (PCOS). Materials and methods: The study was conducted with 25 young women with PCOS and 25 young healthy women, between 18 and 35 years of age. Plasma asymmetric dimethylarginine (ADMA) levels, serum nitric oxide (NO) levels, and homeostatic model assessment of insulin resistance (HOMA-IR) rates were measured in both the patient and control groups. Results: Plasma ADMA levels were significantly higher in PCOS patients than in the controls (P = 0.001). Serum NO levels were significantly lower in patients …


Pittsburgh Sleep Quality Index Scores And Their Relationship With Body Measurements In Late Menopause Patients, Ayli̇n Ayrim, Esra Aktepe Keski̇n, Duygu Özol Jan 2014

Pittsburgh Sleep Quality Index Scores And Their Relationship With Body Measurements In Late Menopause Patients, Ayli̇n Ayrim, Esra Aktepe Keski̇n, Duygu Özol

Turkish Journal of Medical Sciences

With an increase in life expectancy, women live about one-third of their lives in the postmenopausal period. Our aim was to investigate the findings regarding quality of sleep and sleep apnea in postmenopausal women and research the relationship between sleep complaints and body measurements. Materials and methods: The Pittsburgh Sleep Quality Index (PSQI) was administered to all participants and their height, weight, and neck circumferences were measured. Results: A total of 206 patients (mean age: 61.4 ± 8.8 years) were included. Their mean weight gain after menopause was 8.1 ± 12.8 kg, and their mean neck circumference and body mass …