Medicine and Health Sciences Commons^™

Query Mesh: Multiroute, Rimma Nehme, Karen Works, Elke Rundensteiner, Elisa Bertino

Cyber Center Publications

We propose to demonstrate a practical alternative approach to the current state-of-the-art query processing techniques, called the “Query Mesh” (or QM, for short). The main idea of QM is to compute multiple routes (i.e., query plans)1, each designed for a particular subset of data with distinct statistical properties. Based on the execution routes and the data characteristics, a classifier model is induced and is used to partition new data tuples to assign the best routes for their processing. We propose to demonstrate the QM framework in the streaming context using our demo application, called the “Ubi-City”. We will illustrate the …

A Hierarchical Approach To Model Web Query Interfaces For Web Source Integration, Thomas Kabisch, Eduard Dragut, Clement Yu, Ulf Leser

Cyber Center Publications

Much data in the Web is hidden behind Web query interfaces. In most cases the only means to "surface" the content of a Web database is by formulating complex queries on such interfaces. Applications such as Deep Web crawling and Web database integration require an automatic usage of these interfaces. Therefore, an important problem to be addressed is the automatic extraction of query interfaces into an appropriate model. We hypothesize the existence of a set of domain-independent "commonsense design rules" that guides the creation of Web query interfaces. These rules transform query interfaces into schema trees. In this paper we …

The Plant Ionome Coming Into Focus, Lorraine Williams, David Salt

Cyber Center Publications

92 elements have been identified on earth and 17 of these are known to be essential to all plants. The essential elements required in relatively large amounts (>0.1% of dry mass) are called macronutrients and include C, H, O, N, S, P, Ca, K, Mg. Those required in much smaller amounts (<0.01% of dry mass) are referred to as micronutrients or trace elements and include Ni, Mo, Cu, Zn, Mn, B, Fe, and Cl. Plant growth and development depends on a balanced supply of these essential elements and thus the plant has a range of homeostatic mechanisms operating to ensure that this is maintained. Beneficial elements which promote growth and may be essential to some taxa, include Na, Co, Al, Se and Si. Elements such as the heavy metal Cd and the metalloid As have no demonstrated biological function in plants, but are nevertheless taken up and cause severe toxicity in most plant species. The concept for this special issue is the plant ionome, a word coined to encompass all these elements and allow focussed discussion and investigations on the mechanisms that co-ordinately regulate these elements in response to genetic and environmental factors reviewed in Salt et al., 2008).

Beyond K-Anonymity: A Decision Theoretic Framework For Assessing Privacy Risk, Guy Lebanon, Monica Scannapieco, Mohamed Fouad, Elisa Bertino

Cyber Center Publications

An important issue any organization or individual has to face when managing data containing sensitive information, is the risk that can be incurred when releasing such data. Even though data may be sanitized before being released, it is still possible for an adversary to reconstruct the original data using additional information thus resulting in privacy violations. To date, however, a systematic approach to quantify such risks is not available. In this paper we develop a framework, based on statistical decision theory, that assesses the relationship between the disclosed data and the resulting privacy risk. We model the problem of deciding …

Dna Sequence Analysis Of Freshwater Eustigmatophyceae, A Potential Source Of Essential Fatty Acids, Sara E. Prior, M. W. Fawley, K. P. Fawley

Journal of the Arkansas Academy of Science

Freshwater Eustigmatophyceae are a group of microalgae that are considered rare and of low diversity, with only a few genera and species in a single order. Some Eustigmatophyceae produce fatty acids that are important nutrients for aquaculture, as well as for human food consumption. In addition, some Eustigmatophyceae produce hydrocarbons that may be useful in biofuel production. In our studies of the diversity of coccoid algae from Itasca State Park, Minnesota, we discovered several isolates that we tentatively identified as Eustigmatophyceae. Preliminary molecular characterization indicated that these isolates were highly diverse and probably represented species new to science. In this …

The Journal Of Undergraduate Research: Volume 07

The Journal of Undergraduate Research

This is the complete issue of the South Dakota State University Journal of Undergraduate Research, Volume 7.

An Analysis Of Drug Dissolution Rates In The Usp 24 Type 2 Apparatus, David Mcdonnell, Brendan Redmond, Deirdre M. D'Arcy, Anne Marie Healy, Owen Corrigan

Articles

This paper applies boundary layer theory to the process of drug dissolution in the USP 24, Type 2 Apparatus. The mass transfer rate from the top flat surface of a compact in various positions within the device is evaluated by means of a Pohlhausen integral method.

A Generic Approach To Computer-Based Clinical Practice Guideling Management Using The Eca Rule Paradigm And Active Databases, Bing Wu, Kudakwashe Dube

Articles

The increasing demand for reduced cost and improved quality of service in healthcare has prompted the call for better management of medical knowledge. The main emphasis has been on knowledge that is acquired through experience and medical research and then formalised into Clinical Practice Guidelines (CPGs). This paper presents a generic approach to CPG information and knowledge management that uses the Event-Condition-Action (ECA) rule paradigm and active databases within a unified management framework. The paper focuses on an approach for facilitating the use and management of CPGs by clinicians through delivering the CPGs at the point-of-care by a computerised mechanism.

Program And Proceedings: Nebraska Academy Of Sciences 1880–2009, 129th Anniversary Year, One Hundred-Nineteenth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Collegiate Academy: Biology

Earth Science

Collegiate Academy: Chemistry and Physics

Biological and Medical Sciences

Nebraska Wesleyan University Health and Sciences Graduate School Fair

Junior Academy: Senior High Competition

Aeronautics and Space Science, Poster Session

History and Philosophy of Science

Teaching of Science and Math

Maiben Memorial Lecture: Donald Frey, Department of Family Practice, Creighton University Medical Center

Anthropology

Chemistry and Physics

Junior Academy, Junior High Competition

Health Literacy In The Mathematics Classroom: The Iowa Core Curriculum As An Opportunity To Deepen Students’ Understanding Of Mathematics, Elana Joram, Susan Roberts-Dobie, Nadene Davidson

Faculty Publications

By 2012, all high schools in Iowa will be required to incorporate the new Iowa Core Curriculum, followed by elementary and middle schools in 2014 (Iowa Department of Education, 2009). The Iowa Core Curriculum addresses the question: "How is Iowa's educational system preparing our youth for successful lives in the 21st-century global environment?" (Davidson, 2009). It consists of core content standards, and identifies essential concepts and skills for content areas. The Iowa Core Curriculum also includes the ―21st Century Skills‖ of ―health, financial, technology, and civic literacy, and employability skills. These skills are to be infused into existing subject matter …

Biomonitoring For Exposure To Trace Elements In Utero : Analysis Of The Human Placenta, Pamela Catherine Kruger

Legacy Theses & Dissertations (2009 - 2024)

The placenta forms in eutherian mammals, and is responsible for the nutrition of the developing fetus. However, maternal exposure to environmental pollutants both before and during pregnancy may result in the passage of toxins through the placental barrier and into fetal tissues. The placenta is the only organ derived from both maternal and fetal tissues, and establishes a link between the fetus and the environmental exposures of the mother. The analysis of placentae for the presence of environmental pollutants offers the possibility of exposure measurements in both the mother and the developing fetus. Specifically, trace element determination in human placentae …

Barriers Encountered During Enrollment In An Internet-Mediated Randomized Controlled Trial, Lorraine R. Buis, Adrienne W. Janney, Michael L. Hess, Silas A. Culver, Caroline R. Richardson

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Online technology is a promising resource for conducting clinical research. While the internet may improve a study's reach, as well as the efficiency of data collection, it may also introduce a number of challenges for participants and investigators. The objective of this research was to determine the challenges that potential participants faced during the enrollment phase of a randomized controlled intervention trial of Stepping Up to Health, an internet-mediated walking program that utilized a multi-step online enrollment process.

Methods

We conducted a quantitative content analysis of 623 help tickets logged in a participant management database during the enrollment …

Preparation And Characterization Of Some Substituted Benzyl N-Nitrosocarbamates Containing An N-2-(Methylthio)Ethyl Or A Bis(2-Aminoethyl)Sulfide Functionality, Satya Venkata, Eric Shamo, Vladimir Benin

Chemistry Faculty Publications

The synthesis and characterization of some substituted benzyl N-nitrosocarbamates with an N-2-(methylthio)ethyl or a bis(2-aminoethyl)sulfide functionality is reported, as a part of a long-term goal to design and prepare novel photolabile structures that could be used as substances for controlled release of alkylating and/or crosslinking agents. The synthesis was accomplished by reaction of benzyl chloroformates with the corresponding amines, resulting in the preparation of carbamates. The latter were subsequently nitrosated, utilizing two different N-nitrosation methods, to yield the target structures.

Liquid Chromatography-Tandem Mass Spectrometry For The Determination Of Methylprednisolone In Rat Plasma And Liver After Intravenous Administration Of Its Liver-Targeted Dextran Prodrug, Shuang-Qing Zhang, Helen R. Thorsheim, Suman Penugonda, Venkateswaran C. Pillai, Quentin R. Smith, Reza Mehvar

Pharmacy Faculty Articles and Research

A specific and sensitive liquid chromatography (LC)-tandem mass spectrometric method for quantitative determination of methylprednisolone (MP) in rat plasma and liver was developed and validated using triamcinolone acetonide as an internal standard. Liquid-liquid extraction using tert-butyl methyl ether was used to extract the drug and the internal standard from plasma and liver. The separation of MP was performed on a C(18) column with a mobile phase of acetonitrile:0.5% formic acid aqueous solution (85:15, v/v) over 4 min. The assay was based on the selected reaction monitoring transitions at m/z 375 -> 161 for MP in plasma, 375 -> 357 for …

Mathematical Aids Epidemic Model: Preferential Anti-Retroviral Therapy Distribution In Resource Constrained Countries, Nadia Abuelezam

HMC Senior Theses

HIV/AIDS is one of the largest health problems the world is currently facing. Even with anti-retroviral therapies (ART), many resource-constrained countries are unable to meet the treatment needs of their infected populations. ART-distribution methods need to be created that prevent the largest number of future HIV infections. We have developed a compartment model that tracks the spread of HIV in multiple two-sex populations over time in the presence of limited treatment. The model has been fit to represent the HIV epidemic in rural and urban areas in Uganda. With the model we examine the spread of HIV among urban and …

E-85 Vs. Regular Gasoline: Effects On Engine Performance, Fuel Efficiency, And Exhaust Emissions, Jordan W. Steinhaus, Donald M. Johnson, George W. Wardlow

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

This study compared the performance, fuel efficiency, and exhaust emissions of a 2.61 kW engine fueled with regular unleaded gasoline (87 octane) and an 85% ethanol blend (E85) under two load conditions. Four 1-h tests were conducted with each fuel at both governor’s maximum (3400 rpm) and peak torque (2800 rpm) conditions for a total of 16 tests. At governor’s maximum engine speed, there were no significant differences (p>0.05) between fuels for engine torque, power, specific carbon dioxide (sCO2 ), specific carbon monoxide (sCO), specific hydrocarbons (sHC), or specific oxides of nitrogen (sNOX) emissions. However, there was a significant …

Measurement Of Transient Smoke Emissions From Diesel And Biodiesel Fuel Blends In An Agricultural Tractor, Kristin M. Pennington, Sonia R. Munoz, Donald M. Johnson, George Wardlow

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Transient smoke emissions pose potential hazards to human health and the environment. With the increased popularity of biodiesel, there is a need to determine if these fuels produce different levels of particulate matter in exhaust emissions. This study examined the transient smoke emissions of three fuels: No. 2 petroleum diesel fuel (D2, ASTM D 975), a blend of 20% biodiesel and 80% petroleum diesel (B20, ASTM 6751), and a 100% pure biodiesel derived from animal fats (B100, ASTM D 6751). Measurements of smoke emissions were taken using the SAE J1677 snap acceleration test procedure on a John Deere 3203 compact …

Faculty Should Consider Peer Review As A Means Of Improving Students' Scientific Reasoning Skills, Briana Timmerman, Denise Strickland

Journal of the South Carolina Academy of Science

No abstract provided.

The Integrated Biomedical Science Graduate Program At The University Of South Carolina, Richard Hunt

Journal of the South Carolina Academy of Science

No abstract provided.

Synthesis Of Fatty Acid Binding Protein Inhibitors: A New Approach For Diabetes Treatment, Shekelia Baccus, M. Perry Davis Jr, David R. Magnin

Journal of the South Carolina Academy of Science

No abstract provided.

Generation Of A Retroviral Vector That Expresses An Anti-Hiv-1 Tat Hammerhead Ribozyme, Lindsey E. Padgett, William H. Jackson

Journal of the South Carolina Academy of Science

No abstract provided.

The Effect Of Incubation Time On The Generation Of Benzene In Sierra Mist Free, Sarah Law

Journal of the South Carolina Academy of Science

No abstract provided.

Downregulation Of Hiv-1 Vif By A Hammerhead Ribozyme Expressed From A Retroviral Vector, Audrey M. Hendley, William Jackson

Journal of the South Carolina Academy of Science

No abstract provided.

Temperature Changes Resulting From A Gaalas Laser In The Decontamination Of A Failing Dental Implant, Adam B. Oppenheimer

Journal of the South Carolina Academy of Science

No abstract provided.

Where Do Mouse Embryos Thrive Best? Comparison Of Mammalian Embryo Development Under Varying Laboratory Environments, Yvonne K. Kao, H. Lee Higdon Iii, Ph.D, Jennifer E. Graves-Herring , M.S., William R. Boone Ph.D

Journal of the South Carolina Academy of Science

No abstract provided.

Complementary Responses To Mean And Variance Modulations In The Perfect Integrate-And-Fire Model, Joanna R. Wares, Todd W. Troyer

Department of Math & Statistics Faculty Publications

In the perfect integrate-and-fire model (PIF), the membrane voltage is proportional to the integral of the input current since the time of the previous spike. It has been shown that the firing rate within a noise free ensemble of PIF neurons responds instantaneously to dynamic changes in the input current, whereas in the presence of white noise, model neurons preferentially pass low frequency modulations of the mean current. Here, we prove that when the input variance is perturbed while holding the mean current constant, the PIF responds preferentially to high frequency modulations. Moreover, the linear filters for mean and variance …

The Influence Of Familism On Descriptive And Injunctive Norms In Predicting The Intention To Eat A Vegetarian Diet Among Chinese Seventh-Day Adventists, See Wei Toh

Loma Linda University Electronic Theses, Dissertations & Projects

According to the theory of planned behavior (TpB), one determinant of intention to engage in a behavior is the subjective norm. Various studies have found that subjective norm is often the weaker predictor of intention compared to perceived behavioral control and attitude. This study examined whether familism (emphasis on the family rather than the individual) would contribute positively to the predictive power of the TpB model through interactions with the family portion of descriptive and injunctive norms. Descriptive and injunctive norms are component variables of the subjective norm. A sample of 284 adult Chinese Seventh-day Adventists 18 years and older …

Hydroxyl Radical Is Produced Via The Fenton Reaction In Submitochondrial Particles Under Oxidative Stress: Implications For Diseases Associated With Iron Accumulation, Carin Thomas, Melissa M. Mackey, Amy A. Diaz, David P. Cox

All Faculty Scholarship for the College of the Sciences

Mitochondrial dysfunction and reactive oxygen species (ROS) are often implicated in diseases involving oxidative stress and elevated iron. As mitochondria produce ATP by oxidative phosphorylation, ROS by-products are generated from the electron transport chain. Although superoxide and hydrogen peroxide have been thoroughly investigated, little evidence documents hydroxyl radical (HO•) production in mitochondria. In order to determine whether HO• is generated under oxidative stress conditions by a Fenton-type mechanism, bovine heart submitochondrial particles were examined for HO• in the presence and absence of iron ligands, antioxidant enzymes and HO• scavengers. HO• was measured as 2,3- and 2,5-dihydroxybenzoic acid (DHBA), using HPLC …

Advances And Applications Of Dezert-Smarandache Theory (Dsmt) For Information Fusion (Collected Works), Vol. 3, Florentin Smarandache, Jean Dezert

Branch Mathematics and Statistics Faculty and Staff Publications

This volume has about 760 pages, split into 25 chapters, from 41 contributors. First part of this book presents advances of Dezert-Smarandache Theory (DSmT) which is becoming one of the most comprehensive and flexible fusion theory based on belief functions. It can work in all fusion spaces: power set, hyper-power set, and super-power set, and has various fusion and conditioning rules that can be applied depending on each application. Some new generalized rules are introduced in this volume with codes for implementing some of them. For the qualitative fusion, the DSm Field and Linear Algebra of Refined Labels (FLARL) is …

Probing The Urea Dependence Of Residual Structure In Denatured Human Α-Lactalbumin, Victoria A. Higman, Heike I. Rösner, Raffaella Ugolini, Lesley H. Greene, Christina Redfield, Lorna J. Smith

Chemistry & Biochemistry Faculty Publications

Backbone ¹⁵N relaxation parameters and ¹⁵N–¹H^N residual dipolar couplings (RDCs) have been measured for a variant of human α-lactalbumin (α-LA) in 4, 6, 8 and 10 M urea. In the α-LA variant, the eight cysteine residues in the protein have been replaced by alanines (all-Ala α-LA). This protein is a partially folded molten globule at pH 2 and has been shown previously to unfold in a stepwise non-cooperative manner on the addition of urea. ¹⁵N R₂ values in some regions of all-Ala α-LA show significant exchange broadening which is reduced as the urea …