Medicine and Health Sciences Commons^™

Use Of Silica Dust And Lunar Simulants For Assessing Lunar Regolith Exposure, Layzamarie Irizarry-Colon

USF Tampa Graduate Theses and Dissertations

The utilization of the lunar regolith holds immense potential for future space exploration, but the potential health risks associated with lunar regolith are a significant concern. This literature review seeks to critically assess the use of silica and lunar simulants standards and permissible exposure limits (PELs) to evaluate the adverse health effects of lunar regolith. The literature review covers an extensive analysis of existing research, health risks, toxicological properties, and physical and chemical composition associated with silica, lunar simulants, and lunar regolith by using three main sources: regulations, scholarly articles, and Kennedy Space Center (KSC) discussion. This comprehensive analysis forms …

Entanglements Of Teenage Food Security Within High School Pantries In Pinellas County, Florida, Karen T. Díaz Serrano

USF Tampa Graduate Theses and Dissertations

Food insecurity has the ability to shape an individual’s or a family’s everyday life and take emotional, psychological, and physical tolls. Among adolescents, not having access to nutritious food could lead to physical effects during growth and development. Moreover, the stress and anxiety of not knowing where their next meal is coming from and the social stigma associated with being food insecure can have negative effects on mental health. A recent solution to these issues is locating food pantries in high schools. Purpose: This exploratory study examined how high school students in Pinellas County, Florida perceive the use of a …

Combining Frameworks To Improve Military Health System Quality And Cybersecurity, Dr. Maureen L. Schafer, Dr. Joseph H. Schafer

Military Cyber Affairs

Existing conceptual frameworks and commercially available technology could be considered to rapidly operationalize the use of Quality Measures (QM) within military health systems (Costantino et al. 2020). Purchased healthcare as well as digital healthcare services have paved the way for data collection from multiple information systems thus offering stakeholders actionable intelligence to both guide and measure healthcare outcomes. However, the collection of data secondary to Smart Devices, disparate information systems, cloud services, and the Internet of Medical Things (IOMT) is a complication for security experts that also affect clients, stakeholders, organizations, and businesses delivering patient care. We have combined three …

Apkcs Role In Neuroblastoma Cell Signaling Cascades And Implications Of Apkcs Inhibitors As Potential Therapeutics, Sloan Breedy

USF Tampa Graduate Theses and Dissertations

Neuroblastoma (NB) is a cancer that develops in the neuroblasts. It is the most common cancer in children under the age of 1 year, accounting for approximately 6% of all cancers. The prognosis of NB is linked to both age and degree of cell differentiation. This results in a range of survival rates for patients, with outcomes ranging from recurrence and mortality to high survival rates and tumor regression. Our previous work indicated that PKC-ι promotes cell proliferation in NB cells through the PKC-ι/Cdk7/Cdk2 cascade. We report on two atypical protein kinase inhibitors as potential therapeutic candidates against BE(2)-C and …

A Multiple Input Multiple Output Framework For The Automatic Optical Fractionator-Based Cell Counting In Z-Stacks Using Deep Learning, Palak Dave

USF Tampa Graduate Theses and Dissertations

Quantifying cells in a defined region of biological tissue is critical for many clinical and preclinical studies, especially in pathology, toxicology, cancer, and behavior. Unbiased stereology is the state-of-art method for quantification of the total number and other morphometric parameters of stained objects in a defined region of biological tissue. As part of a program to develop accurate, precise, and more efficient automatic approaches for quantifying morphometric changes in biological tissue, our group has shown that both deep learning-based and hand-crafted algorithms can estimate the total number of histologically stained cells at their maximal profile of focus in extended depth …

Accelerating Multiparametric Mri For Adaptive Radiotherapy, Shraddha Pandey

USF Tampa Graduate Theses and Dissertations

MR guided Radiotherapy (MRgRT) marks an important paradigm shift in the field of radiotherapy. Superior tissue contrast of MRI offers better visualization of the abnormal lesions, as a result precise radiation dose delivery is possible. In case of online treatment planning, MRgRT offers better control of intratumoral motion and quick adaptation to changes in the gross tumor volume. Nonetheless, the MRgRT process flow does suffer from some challenges that limit its clinical usability. The primary aspects of MRgRT workflow are MRI acquisition, tumor delineation, dose map prediction and administering treatment. It is estimated that the acquisition of MRI takes around …

Nonparametric Estimation Of Transition Probabilities In Illness-Death Model Based On Ranked Set Sampling, Ying Ma

USF Tampa Graduate Theses and Dissertations

The ranked set sampling (RSS) design is applied widely in agriculture, environmental science, and medical research where the exact measurements of sampling units is costly, but sampling units can be ranked by a correlated concomitant variable. RSS is usually a cost-efficient alternate to simple random sampling (SRS) for selecting more representative samples. This study presents a novel methodology to investigate the nonparametric estimation of transition probabilities in illness-death model using the RSS design. We study the Aalen–Johansen estimator of transition probabilities in illness-death Markov model based on RSS design under random right censoring time and propose nonparametric estimators of the …

On The Reliability Of Wearable Sensors For Assessing Movement Disorder-Related Gait Quality And Imbalance: A Case Study Of Multiple Sclerosis, Steven Díaz Hernández

USF Tampa Graduate Theses and Dissertations

Approximately 33 million American adults had a movement disorder associated with medication use, ear infections, injury, or neurological disorders in 2008, with over 18 million people affected by neurological disorders worldwide. Physical therapists assist people with movement disorders by providing interventions to reduce pain, improve mobility, avoid surgeries, and prevent falls and secondary complications of neurodegenerative disorders. Current gait assessments used by physical therapists, such as the Multiple Sclerosis Walking Scale, provide only semi-quantitative data, and cannot assess walking quality in detail or describe how one’s walking quality changes over time. As a result, quantitative systems have grownas useful tools …

Managing Incomplete Data In The Patient Discharge Summary To Support Correct Hospital Reimbursements, Fadi Naser Eddin

USF Tampa Graduate Theses and Dissertations

The patient discharge summary is a document that conveys the patient's story to other healthcare practitioners, external users, and, most importantly from a financial perspective, health insurers. A defect or incompleteness in the patient's discharge summary will result in delays in the collection process through denial of the entire or partial reimbursement claim or, in the best-case scenario, delay until the discharge summary issue is resolved. The purpose of this project is to address the issue of the incompleteness of discharge summary from the perspective of healthcare providers, with the goal of understanding, diagnosing, and intervening in the research problem. …

Managing Health Locus Of Control In Patient-Provider Relationships, James Wallace

USF Tampa Graduate Theses and Dissertations

Patient locus of control is a strong determinant of health outcomes, yet health care professionals do not typically address it in care plans. In fact, management of most medical conditions is hindered because the treating physician has little information about the patient’s locus of control. This research addresses the question “How can locus of control be used to enable health care practitioners to improve medical outcomes?”

Research Methodology. Using an engaged scholarship approach incorporating the Elaborated Action Design Research methodology, the research drives the guided, emergent design of a novel protocol and two separate artifacts for management of health locus …

Comparison Of The Effectiveness Of Disinfectant-Impregnated Wipes Versus Detergent Wipes For Surface Decontamination, Jacob Amadin

USF Tampa Graduate Theses and Dissertations

Over time, there is an increased need to adopt more advanced and effective ways of disinfection. The emergence of the coronavirus-2019 (COVID-19) pandemic reminded the world on the importance of disinfection. Disinfection has been a routine in the healthcare setting. However, with the current pandemic problem, it is more prominently and persistently done in the domestic setting and other business settings beyond healthcare. As such, the use of most disinfectants and detergent wipes to achieve a near sanitized environment has become a common practice around the globe. This research presents the efficacy of disinfectant impregnated versus detergents wipes through comparison. …

Microbiological Study In A Gneissic Cave From Sri Lanka, With Special Focus On Potential Antimicrobial Activities, Ethige Isuru P. Silva, Pathmakumara Jayasingha, Saman Senanayake, Anura Dandeniya, Dona Helani Munasinghe

International Journal of Speleology

The emergence of antibiotic resistance is a global health crisis, thus the search for novel antimicrobial compounds has become a continuous necessity. Underexplored and extreme environments, such as cave ecosystems, have been identified as a promising potential source for the discovery of novel microorganisms with novel antimicrobial compounds (AMC). This study presents the first cave microbiological investigation in Sri Lanka, with a special preference for bioprospecting of novel AMC. The cave sediment characterization demonstrated the presence of close to strong acidic conditions (pH 3.1 – 3.3) and thus indicates the possibility of isolating acidophilic microorganisms. Eight cave wall/ceiling fungal strains …

Covid-19 And Quantitative Literacy: Focusing On Probability, Michael A. Lewis

Numeracy

The COVID-19 pandemic is arguably the worst crisis the world has faced, so far, in this new century. We haven’t seen a pandemic like this since the 1918 Flu at the beginning of the last century, and, as of this writing, there appears to be no end in sight. What those of us who’re focused on quantitative methods have noticed, in addition to the many people dying, becoming ill, and losing their livelihoods, is the importance of quantitative literacy to an understanding of what’s going on. That’s what this article is about. Specifically, it’s about how the COVID-19 pandemic is …

Active Deep Learning Method To Automate Unbiased Stereology Cell Counting, Saeed Alahmari

USF Tampa Graduate Theses and Dissertations

Cell quantification in histopathology images plays a significant role in understanding and diagnosing diseases such as cancer and Alzheimers. The gold-standard for quantifying cells in tissue sections is the unbiased stereology approach. Unfortunately, in unbiased stereology current practices rely on a well-trained human to manually count hundreds of cells in microscopy images. However, this human-based manual approach is time-consuming, labor-intensive, subject to human errors, recognition bias, fatigue, variable training, poor reproducibility, and inter-observer error. Thus, the lack of high-throughput technology for automating unbiased stereology analyses remains a major obstacle to further progress in a wide range of neuroscience and cancer …

Do Similar Exposure Groups (Seg) Differ From Air Force Base To Air Force Base? A Combat Arms Training And Maintenance (Catm) Noise Exposure Comparison Of Moody Afb And Macdill Afb., Miriam F. Escobar

USF Tampa Graduate Theses and Dissertations

Noise is a common hazard for the military. The Department of Defense has set an Occupational Exposure Limit for noise at 85 dBA. The Air Force manages exposures using similar exposure groups (SEGs) which are formed at each Air Force Base. The purpose of this study was to compare the noise levels in SEGs in two Air Force bases across distance and time, and to review the effectiveness of the Air Force Hearing Conservation Program over distance and time. The SEGs chosen were Combat Arms Training and Maintenance (CATM) at Moody Air Force Base and MacDill Air Force Base because …

Identification Of Patterns And Disruptions In Ambient Sensor Data From Private Homes, Yan Wang

USF Tampa Graduate Theses and Dissertations

The world’s population is rapidly aging and the increasing demand for home and health care services from this aging population brings unprecedented challenges to the economy and society. Ambient-assisted smart homes, residences equipped with ambient sensors to monitor the resident’s daily activities in a continuous and unobtrusive way, present great potential to manage the growing care service needs of this older population segment, and enable them to age-in-place.

Despite growing research, using ambient sensor data from private homes to monitor daily activities, health and wellness still faces significant challenges. To study ambient sensor data from private homes where annotated data …

Complexities Of Data, Tasks And Workflows In Health It Management, Gaurav Jetley

USF Tampa Graduate Theses and Dissertations

This dissertation focuses on three key aspects in health IT management: (1) Complexities in the collection of health data in electronic health record (EHR) systems and the use of EHR data in research, (2) Complexities of collaboration between physicians and AI for improving healthcare delivery, and (3) Complexities of workflows and collaborations between healthcare organization (HCO) staff during the delivery of care. The first dissertation essay (Chapter 1) examines the key data quality issues that arise in recorded health information in EHR systems, provides quality thresholds that the data needs to meet for mitigating errors and increasing reproducibility of downstream …

Exploration Of Factors Associated With Perceptions Of Community Safety Among Youth In Hillsborough County, Florida: A Convergent Parallel Mixed-Methods Approach, Yingwei Yang

USF Tampa Graduate Theses and Dissertations

Introduction: Youth perceived safety is not only linked to crime and violence in a neighborhood but is also associated with health risk behaviors and certain neighborhood characteristics. The purpose of this mixed-methods study was to measure the co-occurring effects of individual and community risk factors by conducting a secondary data analysis using structural equation modeling (SEM) and to explore reasons for youth feeling safe/unsafe in their community using photovoice methodology.

Methods: Syndemic theory/model served as the theoretical framework to guide this mixed-methods study with a convergent parallel design. The quantitative strand (first manuscript) utilized an existing dataset collected from middle …

Effects Of Quantitative Literacy On Healthcare Decision-Making: An Aural Context, Robert G. Root, Sonia Bhala

Numeracy

We propose a relationship between sensory modality, numerical formatting, and performance on a survey simulating healthcare decision-making. We examine the current literature on aural health literacy, and specifically aural literacy coupled with health numeracy. We then create a survey instrument called the Bhala test for this purpose and demonstrate that it is moderately internally consistent and provides results that correlate with the NUMi assessment, a widely accepted measure of health numeracy. The quantitative information provided in the Bhala test has two treatments, percentage and natural frequency formats, in an effort to determine which format is easier for subjects to use …

Introducing A Mobile Health Care Platform In An Underserved Rural Population: Reducing Assimilations Gaps On Adoption And Use Via Nudges, Joseph Hodges

USF Tampa Graduate Theses and Dissertations

Rural communities are often overlooked when it comes to offering cutting edge consumer healthcare technologies. Mobile applications usually exclude populations in rural demographics due to the infrastructure requirements and available technology in the region. The population studied is a low income rural health plan in southwest Georgia. They are uniquely considered as they have the highest healthcare costs in the U.S. and are compared to healthcare costs among higher income populations like Vail, Colorado. Innovations, such as mobile healthcare applications, have the capacity to offset some of these costs, but even if adoption occurs, this does not guarantee use will …

Sundaas Story: A Mixed-Methods Study Of Household Sanitation Provisioning In Urban Informal Housing In India, Sarita Vijay Panchang

USF Tampa Graduate Theses and Dissertations

The aims of this research were to examine sanitation insecurity in urban informal housing through the lens of the built environment, social disparities, and health implications. While the Millennium Development Goals for halving the global proportion of people without access to safe drinking water were met ahead of schedule, progress fell short for sanitation, creating new objectives for the Sustainable Development Goals to be met in 2030. Much research in the Global South is dedicated to community-level sanitation promotion, but often presumes a rural rather than urban setting. Urban informal housing settings constitute a unique challenge due to the range …

The Ability Of The U.S. Military’S Wbgt-Based Flag System To Recommend Safe Heat Stress Exposures, David R. Almario

USF Tampa Graduate Theses and Dissertations

The U.S. military currently uses a flag system based on wet-bulb globe temperature (WBGT) and metabolic rate to recommend heat stress exposure limits. This paper addresses the ability of the flag system to recommend safe heat exposures in a non-military population.

Two progressive heat stress studies provided data on 528 observations of safe or unsafe exposures of 4 hours over a range of WBGT conditions and metabolic rates using 29 participants wearing woven cotton clothing. For the two studies, range of WBGT conditions was 25 to 42C, and the range of metabolic rates was 100 to 650 watts. These exposures …

Comparison Of Modeled And Measured Pesticide Concentrations In Air, Trenell Davis Boggans

USF Tampa Graduate Theses and Dissertations

Chlorpyrifos (CPF) is a popular organophosphorus insecticide that is heavily used in the agriculture industry as a means of pest control. Chlorpyrifos is known for its toxic effect to inhibit the enzyme acetylcholinesterase (ACHE) in humans and is widely used in areas of California where the site of application is close to occupied areas, such that exposures to residents and bystanders can occur due to secondary drift. Secondary drift refers to the volatilization of a pesticide from the surface to which it was applied (e.g. soil or plant foliage) and subsequent off-site movement in ambient air. Secondary drift is different …

Emotion Recognition Using Deep Convolutional Neural Network With Large Scale Physiological Data, Astha Sharma

USF Tampa Graduate Theses and Dissertations

Classification of emotions plays a very important role in affective computing and has real-world applications in fields as diverse as entertainment, medical, defense, retail, and education. These applications include video games, virtual reality, pain recognition, lie detection, classification of Autistic Spectrum Disorder (ASD), analysis of stress levels, and determining attention levels. This vast range of applications motivated us to study automatic emotion recognition which can be done by using facial expression, speech, and physiological data.

A person’s physiological signals such are heart rate, and blood pressure are deeply linked with their emotional states and can be used to identify a …

Particles In Welding Fumes, Rebecca T. Williams

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to investigate whether or not differing base metals and filler wires used during welding processes contributed to differing amounts of ultrafine particles (UFP) and nanoparticles being emitted during the welding procedure. The study was also conducted to determine UFP and nanoparticle exposure in the breathing zones of the welders as well as the breathing zones of pipefitters and fire watchers, who commonly sit 6ft behind the welding arc. In order to determine if UFP and NP exposures differed with base metal and filler wire, all welding processes utilized the same welding machine for metal …

Ripple Effects Of The Belo Monte Dam: A Syndemic Approach To Addressing Health Impacts For The Downstream Community Of Gurupá, Cynthia A. Pace

USF Tampa Graduate Theses and Dissertations

This dissertation examines the public health impacts of a large dam project on a downstream community using the framework of Syndemic Theory. The particular focus is the Belo Monte Dam, located in the Brazilian Amazon, and its impact on the community of Gurupá, Pará. At the present time the Belo Monte Dam, which is nearing completion, stands out in scale as being the world’s third largest dam complex. Gurupá is a community well known (and well-studied) in the social science literature as Amazon Town. The aims of this study are to assess the pre-existing public health of Gurupá, as well …

Design And Implementation Of A Ferrocement Improved Cookstove In Rural Panama, Josh Donegan

USF Tampa Graduate Theses and Dissertations

Household air pollution contributes to the premature death of more than 4 million people annually. Improved cookstoves are one technological intervention that can potentially reduce exposure to household air pollution. However, improved cookstove implementation programs need to consider measures to increase sustainability and promote long-term adoption. The objectives of this research were 1) to develop and implement a new ferrocement cookstove for Peña Blanca, a rural indigenous community in the Ngäbe-Bugle region of Panama, 2) to evaluate its potential sustainability in comparison to the most common cooking technologies observed in the community, 3) to prepare a construction manual for the …

Effectiveness Of Biocide Substitution And Management Plan Implementation For The Control Of, Adelmarie Bones

USF Tampa Graduate Theses and Dissertations

After the notorious outbreak and discovery of Legionella bacteria in 1976, the waterborne pathogen was added to the list of disease-causing agents associated with the built environment. Legionella pneumophila was discovered when it was identified as the agent that caused 34 deaths and an outbreak of pneumonia-like symptoms in several attendees of the 1976 American Legion Convention held in Philadelphia (OSHA, 2017).

Recently published data from the year 2015 reported more than 6,000 Legionnaires’ cases identified in the United States (CDC, 2016). This is a concerning number given that one in every ten infected persons will die of the disease. …

Angiostrongylus Cantonensis: Epidemiologic Review, Location-Specific Habitat Modelling, And Surveillance In Hillsborough County, Florida, U.S.A., Brad Christian Perich

USF Tampa Graduate Theses and Dissertations

Angiostrongylus cantonensis is a parasitic nematode endemic to tropical and subtropical regions and is the leading cause of human eosinophilic meningitis. The parasite is commonly known as rat lungworm because the primary host in its lifecycle is the rat. A clinical overview of rat lungworm infection is presented, followed by a literature review of rat lungworm epidemiology, risk factors, and surveillance projects. Data collected from previous snail surveys in Florida was considered alongside elevation, population per square kilometer, median household income by zip code territory, and normalized difference vegetation index specific to the geographic coordinates from which the snail samples …

Strategies To Adjust For Response Bias In Clinical Trials: A Simulation Study, Victoria R. Swaidan

USF Tampa Graduate Theses and Dissertations

Background: Response bias can distort treatment effect estimates and inferences in clinical trials. Although prevention, quantification, and adjustments have been developed, current methods are not applicable when subject-level reliability is used as the measure of response bias. Thus, the objective of the current study is to develop, test, and recommend a series of bias correction strategies for use in these cases. Methods: Monte Carlo simulation and logistic regression modeling were used to develop the strategies, examining the collective impact of sample size (N), effect size (ES), reliability distribution, and response style on estimating the treatment effect size in a series …