Medicine and Health Sciences Commons^™

La Calidad Del Agua Potable En Arica, Con Respecto A La Salud, Emily Lubell

Independent Study Project (ISP) Collection

Water is essential to sustain life, and the availability of safe drinking water is a concern throughout the world. This study examines the potential negative health effects related to drinking the potable water in Arica, Chile. It also looks at who has access to purified water. This study was implemented over a span of four weeks in which information was collected from different local resources including, the potable water distributor, private water vendors, professors, and public health service workers. In comparison with 2001, 2009 levels of boron, total hardness and total dissolved solids are higher in concentration. In both 2001 …

The Importance Of Scale For Spatial-Confounding Bias And Precision Of Spatial Regression Estimators, Christopher J. Paciorek

Harvard University Biostatistics Working Paper Series

Increasingly, regression models are used when residuals are spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on the bias and precision of regression coefficients, developing a simple framework in which to understand the key issues and derive informative analytic results. When the spatial residual is induced by an unmeasured confounder, regression models with spatial random effects and closely-related models such as kriging and penalized splines are biased, even when the residual variance components are known. Analytic and simulation results show how the bias …

Smoking Enhances Risk For New External Genital Warts In Men, Dorothy J. Wiley, David Elashoff, Emmanuel V. Masongsong, Diane M. Harper

Dartmouth Scholarship

Repeat episodes of HPV-related external genital warts reflect recurring or new infections. No study before has been sufficiently powered to delineate how tobacco use, prior history of EGWs and HIV infection affect the risk for new EGWs. Behavioral, laboratory and examination data for 2,835 Multicenter AIDS Cohort Study participants examined at 21,519 semi-annual visits were evaluated. Fourteen percent (391/2835) of men reported or were diagnosed with EGWs at 3% (675/21,519) of study visits. Multivariate analyses showed smoking, prior episodes of EGWs, HIV infection and CD4+ T-lymphocyte count among the infected, each differentially influenced the risk for new EGWs.

Analysis Of Randomized Comparative Clinical Trial Data For Personalized Treatment Selections, Tianxi Cai, Lu Tian, Peggy H. Wong, L. J. Wei

Harvard University Biostatistics Working Paper Series

No abstract provided.

Modeling Thermal Inactivation Of Bacillus Spores, Emily A. Knight

Theses and Dissertations

This research models and analyzes methods to damage Bacillus anthracis spores through heat treatment. AFIT researchers have developed methods to characterize the effects of heating spores to high temperatures and for short durations similar to the thermal pulse of conventional weapon detonation. This research models the current experiment and evaluates the rate of thermal diffusion throughout the spores. A micro-model of the effects of dry and wet heating on a spore is presented. Heating a spore energizes adsorbed, absorbed, and chemically bound water molecules. These energized molecules have greater mobility within the spore, as well as between the spore and …

Reconstructability Analysis In Biomedical Research, Martin Zwick

Complex Systems Faculty Publications and Presentations

This talk explains reconstructability analysis (RA), a graphical modeling methodology based in information theory & graph theory which overlaps more familiar machine learning & statistical methods such as log-linear models & Bayesian networks. The talk reports on the use of RA in a recent bioinformatics study of human gene (SNP) - disease (diabetes) association & epistasis & in some other biomedical applications of RA.

Keywords: Reconstructability Analysis, biomedical research, bioinformatics, categorical data, multivariate statistics, exploratory modeling, confirmatory modeling

Group Comparison Of Eigenvalues And Eigenvectors Of Diffusion Tensors, Armin Schwartzman, Robert F. Dougherty, Jonathan E. Taylor

Harvard University Biostatistics Working Paper Series

No abstract provided.

Retention Of Polarization Signatures In Shg Microscopy Of Scattering Tissues Through Optical Clearing, Oleg Nadiarnykh, Paul J. Campagnola

UCHC Articles - Research

Polarization responses in Second Harmonic Generation (SHG) imaging microscopy are a valuable method to quantify aspects of tissue structure, and may be a means to differentiate normal and diseased tissues. Due to multiple scattering, the polarization data is lost in turbid tissues. Here we investigate if this information can be retained through the use of optical clearing which greatly reduces the scattering coefficient and increases the corresponding mean free path. To this end, we have measured the SHG intensity as a function of laser polarization and the SHG signal anisotropy in murine tendon and striated muscle over a depth range …

Multimeric Hemicellulases Facilitate Biomass Conversion, Zhanmin Fan, Kurt Wagschal, Wei Chen, Michael D. Montross, Charles C. Lee, Ling Yuan

Plant and Soil Sciences Faculty Publications

Two highly active trifunctional hemicellulases were constructed by linking the catalytic portion of a xylanase with an arabinofuranosidase and a xylosidase, using either flexible peptide linkers or linkers containing a cellulose-binding domain. The multifunctional enzymes retain the parental enzyme properties and exhibit synergistic effects in hydrolysis of natural xylans and corn stover.

Immediate Loading Of Unsplinted Implants In The Anterior Mandible For Overdentures, Phillip Roe

Loma Linda University Electronic Theses, Dissertations & Projects

In this one-year prospective study, eight completely edentulous patients were selected from the Loma Linda University School of Dentistry (LLUSD) patient population to participate. There were five male and three female patients, between the ages of 58 and 82 (mean age of 69.1 years). All participants received new maxillary and mandibular complete dentures prior to implant placement. Two 4.0 mm x 13 mm threaded implants with a fluoride-modified, micro-roughened, titanium surface were placed mesial to each mandibular canine position. Locator abutments were connected and torqued to 25 Ncm and primary closure was achieved with a nonresorbable suture material. The Locator …

The Prevalence And Determinants Of Health Risk Behaviors Among High School Students In Mexico, Nellie León

Loma Linda University Electronic Theses, Dissertations & Projects

The Centers for Disease Control and Prevention report that despite health promotion efforts, adolescents continue to engage in behaviors that put them at risk for morbidity and mortality. Alcohol consumption, illicit drug use, smoking, and risky sexual behaviors are among the behaviors that contribute to leading causes of morbidity and mortality in youth; these four behaviors were explored in this study. An observational cross-sectional design was utilized. The Youth Risk Behavior Survey from the Centers for Disease Control and Prevention was utilized to assess the prevalence of the four risk behaviors among high school students in Jalisco, Mexico. Items constructed …

Lsuhsc Facilities Daily Update: March 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2009

LSUHSC Dailly Facilities Updates from March 2009. These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Biweekly Update: March 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2009

LSUHSC Facilities Biweekly Updates from March 13 and 27, 2009.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Crop Updates 2009 - Genetically Modified Crops, Nutrition, Soils, & Others, Wallace Cowling, Art Diggle, Caroline Peek, Frank D'Emden, Fiona Evans, Bob French, Rob Grima, Sam Harburg, Abul Hashem, John Holmes, Jeromy Lemon, Peter Newman, Janet Paterson, Steve Penny, Peter Portman, Mark Slatter, Angus Maclennan, Andrew Wells, Bill Bowden, Wayne Pluske, Wen Chen, Geoff Anderson, Ross Brennan, Richard Bell, Hannah Rigby, Deborah Pritchard, David Collins, Katrina Walton, David Allen, Nancy Penney, Michael Robertson, Roger Lawes, Stephen Davies, Chris Gazey, Breanne Best, David Gartner, Quenten Knight, Joel Andrew, Ryan Pearce, F. C. Hoyle, A. Bennett, Rick Llewellyn, Ken Flower, Julian Krieg, Owen Catto, Cindy Parsons

Crop Updates

This session covers fifteen papers from different authors:

1. Performance of Canola Breeders Roundup Ready^® canola hybrid CHYB-166 in 2008, Wallace Cowling, Canola Breeders Western Australia Pty Ltd

2. The implications of GM glyphosate resistant lupin, Art Diggle, Caroline Peek, Frank D’Emden, Fiona Evans, Bob French, Rob Grima, Sam Harburg, Abul Hashem,, John Holmes, Jeremy Lemon, Peter Newman, Janet Paterson, Steve Penny,Department of Agriculture and Food, Peter Portmann, Agriconnect

3. Nufarm Roundup Ready® Canola Systems Trials— 2008 Mark Slatter, Research and Development …

39th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University

Student Research Conference Select Presentations

No abstract provided.

Lsuhsc Facilities Daily Update: February 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2009

LSUHSC Dailly Facilities Updates from February 2009. These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Biweekly Update: February 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2009

LSUHSC Facilities Biweekly Updates from February 13 and 27, 2009.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Santa Clara Magazine, Volume 51 Number 3, Winter 2009, Santa Clara University

Santa Clara Magazine

18 - EVERYTHING IS ILLUMINATED By Christine Cole. For the first time since the invention of the printing press, artists have put quill pen to paper to hand-write-in calligraphy-the Bible in its entirety. The result is a wonder to behold. And available to readers and gazers at Santa Clara.

24 - HOLD THE LINE By David McKay Wilson. At Harlem's Frederick Douglass Academy, basketball coach Pat Mangan '84 has built a legendary program by making sure his players have their priorities straight. Family first. School second. Then hoops.

28 - LESSONS IN DIPLOMACY. By Sam Scott '96. How Bob LaMonte …

Contribution Of A Portable Air Plasma Torch To Rapid Blood Coagulation As A Method Of Preventing Bleeding, Kuo S. P., O. Tarasenko, J. Chang, S. Popović, C. Y. Chen, H. W. Fan, A. Scott, M. Lahiani, P. Alusta, J. D. Drake, Milka Nikolic

Physics and Astronomy

The effectiveness and mechanism of a low temperature air plasma torch in clotting blood are explored. Both blood droplets and smeared blood samples were used in the tests. The treated droplet samples reveal how blood clotting depends on the distance at which the torch operated, and for how long the droplets have been exposed to the torch. Microscopy and cell count of smeared blood samples shed light on dependencies of erythrocyte and platelet counts on torch distance and exposure time. With an increase of torch distance, the platelet count of treated blood samples increases but is less than that of …

Understanding The Physical Properties That Control Protein Crystallization By Analysis Of Largescale Experimental Data, W. Nicholson Price Ii, Yang Chen, Samuel K. Handelman, Helen Neely, Philip Manor, Richard Karlin, Rajesh Nair, Jinfeng Liu, Michael Baran, John Everett, Saichiu N. Tong, Farhad Forouhar, Swarup S. Swaminathan, Thomas Acton, Rong Xiao, Joseph R. Luft, Angela Lauricella, George T. Detitta, Burkhard Rost, Gaetano T. Montelione, John T. Hunt

Law Faculty Scholarship

Crystallization is the most serious bottleneck in high-throughput protein-structure determination by diffraction methods. We have used data mining of the large-scale experimental results of the Northeast Structural Genomics Consortium and experimental folding studies to characterize the biophysical properties that control protein crystallization. This analysis leads to the conclusion that crystallization propensity depends primarily on the prevalence of well-ordered surface epitopes capable of mediating interprotein interactions and is not strongly influenced by overall thermodynamic stability. We identify specific sequence features that correlate with crystallization propensity and that can be used to estimate the crystallization probability of a given construct. Analyses of …

Predicting The Drug Release Kinetics Of Matrix Tablets, Boris Baeumer, Lipika Chatterjee, Peter Hinow, Thomas Rades, Ami E. Radunskaya, Ian Tucker

Pomona Faculty Publications and Research

In this paper we develop two mathematical models to predict the release kinetics of a water soluble drug from a polymer/excipient matrix tablet. The first of our models consists of a random walk on a weighted graph, where the vertices of the graph represent particles of a drug, excipient and polymer, respectively. The graph itself is the contact graph of a multidisperse random sphere packing. The second model describes the dissolution and the subsequent diffusion of the active drug out of a porous matrix using a system of a partial differential equations. The predictions of both models show good qualitative …

Singlet Oxygen Delivery Through The Porous Cap Of A Hollow-Core Fiber Optic Device, Matibur Zamadar, David Aebisher, Alexander Greer

Faculty Publications

The development of the first photosensitizer/fiber optic device is reported. An oxygen-flowing, fiber-capped configuration is used for the application of heterogeneous, spatially confined singlet oxygen delivery in aqueous media. This is a unique device, unlike other heterogeneous photosensitizers, in which local concentrations of singlet oxygen can be delivered via introduction and withdrawal of the fiber tip.

The Influence Of Affect, Attitude And Usefulness In The Acceptance Of Telemedicine Systems, Soussan Djamasbi,, Ann L. Fruhling, Eleanor T. Loiacono

Information Systems and Quantitative Analysis Faculty Publications

Grounded in current theories of affect this study examines the role positive and negative moods play on the acceptance of a specialized telemedicine system for microbiology consultation and diagnostics, referred to as telepathology. From a laboratory experiment using microbiology laboratory assistants, the notion that healthcare users’ attitude is an important factor in the acceptance behavior of a healthcare information system is supported. A regression analysis of the data revealed the need to tailor the IS Technology Acceptance Model for the healthcare field. Specifically, our results show that ease of use which is thought to be a main antecedent of end-user …

Persuading Consumers To Form Precise Search Engine Queries, Gondy Leroy

CGU Faculty Publications and Research

Today’s search engines provide a single textbox for searching. This input method has not changed in decades and, as a result, consumer search behaviour has not changed either: few and imprecise keywords are used. Especially with health information, where incorrect information may lead to unwise decisions, it would be beneficial if consumers could search more precisely. We evaluated a new user interface that supports more precise searching by using query diagrams. In a controlled user study, using paper-based prototypes, we compared searching with a Google interface with drawing new or modifying template diagrams. We evaluated consumer willingness and ability to …

Archetype Alignment: A Two-Level Driven Semantic Matching Approach To Interoperability In The Clinical Domain, Damon Berry, Jesus Bisbal

Conference Papers

Semantic interoperability between electronic health record systems and other information systems in the health domain implies agreement about the structure and the meaning of the information that is communicated. There are still a number of similar but different EHR system approaches. Some of the newer approaches adopt the two-layer model approach where a generic reference model is constrained by archetypes into valid clinical concepts which can be exchanged. The meaning of the concepts that are represented by an archetype can be conveyed by embedding codes from a commonly recognised terminology at appropriate points in the archetype. However, as the number …

Ua94/6/1 Student / Alumni Personal Papers Western Kentucky University Small Collections, Wku Archives

WKU Archives Collection Inventories

Small collections of personal papers and oral histories relating to the Western Kentucky University.

Foreword For The Special Issue Of Selected Papers From The 1st Acm Sigspatial Workshop On Security And Privacy In Gis And Lbs, Elisa Bertino, Maria Luisa Damiani

Cyber Center Publications

The first Workshop on Security and Privacy in GIS and LBS (SPRINGL 2008) was organized on November 4, 2008 at Irvine (CA) in conjunction with the SIGSPATIAL International Conference on Advances in Geographic Information Systems (ACM GIS 2008). The goal of the SPRINGL workshop series is to provide a forum for researchers working in the area of geospatial data security and privacy. Both security and privacy are critical for geospatial applications because of the dramatic increase and dissemination of geospatial data in several application contexts including homeland security, environmental crises, and natural and industrial disasters. Furthermore, geospatial infrastructures are being …

Generalization Of Acid Properties, Brahim Medjahed, Mourad Ouzzani, Ahmed Elmagarmid

Cyber Center Publications

ACID (Atomicity, Consistency, Isolation, and Durability) is a set of properties that guarantee the reliability of database transactions [2]. ACID properties were initially developed with traditional, business-oriented applications (e.g., banking) in mind. Hence, they do not fully support the functional and performance requirements of advanced database applications such as computer-aided design, computer-aided manufacturing, office automation, network management, multidatabases, and mobile databases. For instance, transactions in computer-aided design applications are generally of long duration and preserving the traditional ACID properties in such transactions would require locking resources for long periods of time. This has lead to the generalization of ACID properties …

Location Privacy In Moving-Object Environments, Dan Lin, Elisa Bertino, Reynold Cheng, Sunil Prabhakar

Cyber Center Publications

The expanding use of location-based services has profound implications on the privacy of personal information. If no adequate protection is adopted, information about movements of specific individuals could be disclosed to unauthorized subjects or organizations, thus resulting in privacy breaches. In this paper, we propose a framework for preserving location privacy in moving-object environments. Our approach is based on the idea of sending to the service provider suitably modified location information. Such modifications, that include transformations like scaling, are performed by agents interposed between users and service providers. Agents execute data transformation and the service provider directly processes the transformed …

Private Queries And Trajectory Anonymization: A Dual Perspective On Location Privacy, Gabriel Ghinita

Cyber Center Publications

The emergence of mobile devices with Internet connectivity (e.g., Wi-Fi) and global positioning capabilities (e.g., GPS) have triggered the widespread development of location-based applications. For instance, users are able to ask queries about points of interest in their proximity. Furthermore, users can act as mobile sensors to monitor traffic flow, or levels of air pollution. However, such applications require users to disclose their locations, which raises serious privacy concerns. With knowledge of user locations, a malicious attacker can infer sensitive information, such as alternative lifestyles or political affiliations. Preserving location privacy is an essential requirement towards the successful deployment of …