Physiology Commons^™

Effects Of Mind–Body Exercises On Schizophrenia: A Systematic Review With Meta-Analysis, Gao Xia Wei, Lin Yang, Kellie Imm, Paul D. Loprinzi, Lee Smith, Xiangyang Zhang, Qian Yu

Faculty and Student Publications

© Copyright © 2020 Wei, Yang, Imm, Loprinzi, Smith, Zhang and Yu. Background: Mind–body exercises (MBEs) have been widely accepted as a complementary therapy for the patients with low exercise tolerance. Currently, the number of experimental studies investigating the effect of MBEs for improving symptoms in people with schizophrenia is increasing. However, results are inconsistent. Methods: We systematically reviewed and meta-analyzed the effects of mind–body exercises on schizophrenia. Seven electronic databases (Pubmed, Web of Science, PsycINFO, Embase, Cochrane Central Register of Controlled Trials [CENTRAL], CNKI and Wangfang) were screened through October 2019 and risks of bias of included studies were …

Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson

Physiology Faculty Publications

In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the identification of novel areas for therapeutic and scientific exploitation. Here, we review the organizational and activational effects of sex hormones on recovery from injury and how these changes impact the long-term health of spinal cord injury (SCI) patients. When determining how sex affects SCI it remains imperative to expand outcomes beyond locomotor recovery and consider other complications plaguing the quality of …

Long Qt Syndrome Type 2: Emerging Strategies For Correcting Class 2 Kcnh2 (Herg) Mutations And Identifying New Patients, Makoto Ono, Don E. Burgess, Elizabeth A. Schroder, Claude S. Elayi, Corey L. Anderson, Craig T. January, Bin Sun, Kalyan Immadisetty, Peter M. Kekenes-Huskey, Brian P. Delisle

Physiology Faculty Publications

Significant advances in our understanding of the molecular mechanisms that cause congenital long QT syndrome (LQTS) have been made. A wide variety of experimental approaches, including heterologous expression of mutant ion channel proteins and the use of inducible pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from LQTS patients offer insights into etiology and new therapeutic strategies. This review briefly discusses the major molecular mechanisms underlying LQTS type 2 (LQT2), which is caused by loss-of-function (LOF) mutations in the KCNH2 gene (also known as the human ether-à-go-go-related gene or hERG). Almost half of suspected LQT2-causing mutations are missense mutations, and functional studies …

Physical Activity, Sedentary Behavior, And Sleep Quality In Adults With Primary Hypertension And Obesity Before And After An Aerobic Exercise Program: Exerdiet-Hta Study, Aitor Martinez Aguirre-Betolaza, Iñigo Mujika, Paul Loprinzi, Pablo Corres, Ilargi Gorostegi-Anduaga, Sara Maldonado-Martín

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior (SB) in healthy adults (HEALTHY, n = 30) and individuals with primary hypertension (HTN) and overweight/obesity (n = 218); assess the effects of an aerobic exercise intervention on physical activity (PA), sedentary behavior (SB), and sleep quality in the HTN group; and evaluate the relationship between objectively measured and subjectively reported PA and SB. Methods: The measurements were performed before a 16-week exercise intervention …

Impact Of Placement Of Fitbit Hr Under Laboratory And Free-Living Conditions, Hyun Chul Jung, Minsoo Kang, Nan Hee Lee, Soeun Jeon, Sukho Lee

Faculty and Student Publications

© 2020 by the authors. Wrist-worn activity monitors have become accessible for measuring physical activities, but an activity monitor's accuracy worn at different placements is not well understood. This study aimed to examine the differences in measurements of heart rates, step counts, and calories estimated from the fitness tracker worn at different locations and the accuracy of Fitbit HR against criterion measures. Thirty-two healthy adults participated in this study. Participants wore Fitbit HR at four different locations (right proximal, distal, and left proximal, distal). Treadmill exercise consisted of five 5-min phases including slow walking and jogging. Free-living activities involved ten …

Determinants Of The Carbon Footprint Of German Swimmers 2020., Ann-Marie Muehlbauer

Master's Theses

The current climate situation is placing our planet and future generations at risk, which demonstrates the urgency to combat climate change and conduct research to support this effort. Calculating the carbon footprint of active sport participation represents an important opportunity to conduct additional research. This study examined the environmental attitudes and practices of swim club members in Germany. The study had three goals: First, to calculate the total and partial carbon footprint of German swimmers; second, to understand how sport organizations induce participants to engage in pro-environmental behavior; and third, to analyze various factors associated with carbon footprint, such as …

Functional Training And Blood Flow Restriction: A Perspective View On The Integration Of Techniques, Marzo E. Da Silva-Grigoletto, Ezequias Pereira Neto, David George Behm, Jeremy P. Loenneke, Cauê Vazquez La Scala Teixeira

Faculty and Student Publications

No abstract provided.

Calculating An Equation To Estimate The Maximum Oxygen Uptake In Lifeguards, Brais Ruibal-Lista, José Palacios-Aguilar, José Antonio Prieto, Sergio López-García, Miguel Santiago-Alonso, José Antonio Cecchini-Estrada, Cristian Abelairas-Gómez

International Journal of Aquatic Research and Education

The aim of this study was to derive an equation that validly and reliably estimates the VO₂ reached in the IPTL, a maximum stress test for lifeguards. From the results obtained in the first part of the research, a multiple linear regression model was identified. A "stepwise" procedure was established as a variable selection method, where the VO_2IPTL was selected as the dependent variable and the maximum time reached in the IPTL (s), the percentage of muscle mass (%) and weight of the participant (kg), as independent variables. This procedure generated a regression model where a high correlation …

Portuguese Lifeguards Performance In Aquatic Rescue: An Exploratory Study, Olga G. Marques Ph.D., José Palacios-Aguilar Ph.D, Henrique G. Melo Mcs., Nuno G. Leitão, Lucia P. Castillo Msc., David Szpilman M.D, Luís Rama Ph.D.

International Journal of Aquatic Research and Education

The objective of the study was to compare the performance of Portuguese lifeguards in two trials of simulated rescue at the beach within a regular continuous workday. Additionally, the study aimed to analyse the influence of experience and initial course syllabus on the rescue performance. A total of 86 Portuguese lifeguards (LG) participated in this study, 69 males and 17 females. The two simulated drowning occurrences were planned to occur at 50 meters from the coastline between 9.00h am and 18.00h pm. The weather conditions, the characteristics of the beach, wave amplitude were also controlled. The results were analysed through …

Acute Effects Of Kinesiology Tape Tension On Soleus Muscle H-Reflex Modulations During Lying And Standing Postures, Yung Sheng Chen, Wei Chin Tseng, Che Hsiu Chen, Pedro Bezerra, Xin Ye

Faculty and Student Publications

Copyright: © 2020 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Kinesiology tape (KT) has been widely used in the areas of sports and rehabilitation. However, there is no gold standard for the tape tension used during a KT application. The purpose of this study was to examine the effects of KT application with different tension intensities on soleus muscle Hoffmann-reflex (H-reflex) modulation during lying and standing postures. Fifteen healthy university …

Translational Regulation Of Environmental Adaptation In Bacteria, Rodney Tollerson Ii, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Bacteria must rapidly respond to both intracellular and environmental changes to survive. One critical mechanism to rapidly detect and adapt to changes in environmental conditions is control of gene expression at the level of protein synthesis. At each of the three major steps of translation—initiation, elongation, and termination—cells use stimuli to tune translation rate and cellular protein concentrations. For example, changes in nutrient concentrations in the cell can lead to translational responses involving mechanisms such as dynamic folding of riboswitches during translation initiation or the synthesis of alarmones, which drastically alter cell physiology. Moreover, the cell can fine-tune the levels …

To Play Or Not To Play: Can An Instrument Really Impact Lip And Tongue Performance?, Robert S. Thiebaud, Takashi Abe, W. Matt Denning, Jeremy P. Loenneke, Micah J. Okerlund, Joe S.J. Ryan, Whitney Boyce, Maggie Mcbride, Jared Hernandez

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. (1) Background: Increasing tongue and lip strength may help improve various speech and swallowing disorders, but it is unclear if instrumentalists who use these muscle groups for long periods of time have greater strength and endurance compared to controls. It is also unclear if instrumentalists can more accurately estimate various exercise intensities. The purpose of this study was to determine differences in lip and tongue strength and endurance between instrumentalists and non-instrumentalists (controls). A secondary purpose was to assess differences in ability to estimate various exercise intensities between the two groups. …

An Investigation Of Stress-Related Factors And Injury Occurrence In Division Iii Ice Hockey Athletes 2020., Christian Kiesel

Master's Theses

Many variables can factor into a student athlete sustaining an injury, but one of the most interesting is stress. The Stress and Injury Model is excellent in explaining how exactly history of stressors, personality, and coping mechanisms play a pivotal role in the stress response. If these three factors cause a negative stress response, then that will lead to an athlete becoming more likely to become injured. This study used 40 ice hockey players from a Division III NCAA institution. Each participant completed the Inventory of College Students’ Recent Life Experiences (ICSRLE) and Pittsburgh Sleep Quality Index (PSQI) every month …

The Effects, Perceptions, And Attitudes Of Previously Sedentary Individuals Starting An Exercise Program, Arlene Moreno, Megan Rasmussen

Loma Linda University Research Reports

Background: Many Americans do not eat healthfully or exercise, which is associated with higher risk of disease. Nutrition and exercise awareness have increased, but people experience barriers preventing lifestyle change. Limited research has been completed on the impact of nutrition education on dietary intake.

Objective: Examine whether starting an exercise program with or without nutrition education can influence dietary choices in previously sedentary individuals, and to determine their perceptions and attitudes.

Design: Mixed methods study gathering quantitative data through a food frequency questionnaire, InBody test, and demographics/exercise activity survey. Qualitative data was gathered through focus groups. Participants …

Cardiovascular And Stride Frequency Differences During Land And Aquatic Treadmill Walking, Jessica Burton, Sarah Duffey, Amber Hammonds, Anna Leduc, Rachel Shumate, John Coons, Ryan T. Conners

International Journal of Aquatic Research and Education

This study examined heart rate (HR) and stride frequency (SF) values of 30 college-aged males and females during dry-land (DL) and aquatic walking (AW). Aquatic walking trials were completed in an underwater treadmill with the water depth at waist level; the water temperature (31℃ ± 0.1℃) and room temperature (26.6℃ ± 0.1℃) were maintained at thermoneutral levels throughout the study. During each walking condition, HR and SF were recorded at treadmill speeds of 1 mph, 2 mph, and 3 mph. Participants were instructed to walk with their hands at their sides swinging as they would when walking on dry-land unless …

Features Of Acceleration And Angular Velocity Using Thigh Imus During Walking In Water, Koichi Kaneda, Yuji Ohgi, Mark Mckean, Brendan Burkett

International Journal of Aquatic Research and Education

Ten participants were assessed while walking in water and on land with wearable inertial measurement units (IMUs) attached to the right thigh. Longitudinal acceleration, anterior-posterior acceleration, and frontal axis angular velocity were measured at 100 Hz, matched with video analysis sampled at 25 Hz during the walking trials. The longitudinal acceleration showed almost 1 g from initial heel contact to 70% of one cycle, and the anterior-posterior acceleration showed a sinusoidal pattern, synchronizing the approximate posture of the thigh in water. The frontal axis angular velocity fluctuated less while walking in water compared with on land, because thigh motion speed …

Determining The Genetic Control Of Neural Tube Malformation Through Genetic Interactions With Idgf3, Elli N. Fox

Honors Projects

Genetic mutations disrupting human neural tube formation can lead to birth defects such as spina bifida and anencephaly. Defects can result in lack of neural tube closure in either the caudal (spina bifida) or cranial (anencephaly) regions. Little is known about the genes that cause these malformations. Researchers have been using the model organism Drosophila melanogaster in an attempt to determine genes responsible for neural tube malformations. Recently, an ortholog of human chitin-like protein, imaginal disc growth factor 3 (Idgf3), has been identified as important in the proper formation of Drosophila egg dorsal appendages. However, the molecular mechanism responsible for …

Kids Don’T Float…And Their Parents Don’T Either: Using A Family-Centered Approach In Alaska’S Kids Don’T Float Program, Michelle E. E. Bauer, Audrey R. Giles, Justina Marianayagam, Kelli M. Toth

International Journal of Aquatic Research and Education

The goal of this experiential report is to outline the adoption of a family-centered Kids Don’t Float approach. We conducted a critical synthesis of information to reflect the expansion of the Kids Don’t Float program into a more family-centered approach. The critical synthesis provided insights into why we should adopt this approach, how it was implemented, and how it influenced drowning incidents compared to the previously used child-centered approach. The adoption of a family-centered approach may contribute to reducing drowning incidents by targeting parents, providing safety information to families, and promoting parental modelling of life jackets. Program evaluators and water …

Switching Off The Pancreatic Islet: Complex Network Analysis Of Multicellular Clusters, Janita Patwardhan

Biology and Medicine Through Mathematics Conference

No abstract provided.

Swimming Pool Environment And Respiratory Health Issues Experienced By Masters Swimmers: Results From A Literature Review And Survey Of United States Masters Swimming Clubs, Jody C. Gan, Julia Snegg, William Harder

International Journal of Aquatic Research and Education

After three members of a Masters adult swim club died of lung cancer, both a literature review and survey were conducted with representatives from 746 United States Masters Swimming clubs to explore a possible relationship between swimming and cancers of the respiratory tract. Six other clubs reported known cancers of the respiratory tract among club members, but none of the other 740 clubs reported a similar cluster of lung cancer. More clubs reported cases of chronic respiratory infections and widespread complaints about air quality. While no studies exploring a relationship between swimming and lung cancer could be found in the …

Swimming Past The Pandemic: Importance Of Evidence-Based Science, Stephen J. Langendorfer Ph.D.

International Journal of Aquatic Research and Education

Swimming Past the Pandemic - URL included

Assessment Of Antebrachial And Carpal Muscle Activity During Smartphone Use: Is “Selfie Wrist” A Real Phenomenon?, Monica Stacy

Honors Theses

Reports in the media by celebrities have sparked an interest in a phenomenon being called “selfie-wrist,” in which smartphone users develop symptoms traditionally associated with carpal tunnel syndrome (CTS). There has been no research to date which investigates the claims of “selfie wrist.” The primary aim of this study was to address the validity of “selfie wrist” claims. The secondary aim of this study was to further investigate the effects of texting on musculoskeletal health, taking into account the differences between texting one-handed versus two-handed, and the effect of using a grip device while texting.

The experiment consisted of an …

The Role Of Central Ace2 And Nrf2 In Sympatho-Excitation: Responses To Central Angiotensin Ii, Anyun Ma

Theses & Dissertations

Sympatho-excitation is a key characteristic in cardiovascular diseases such as chronic heart failure (CHF) and primary Hypertension (HTN). Evidence suggests that increased sympathetic tone is closely related to activation of the Renin-Angiotensin-Aldosterone system (RAAS) in the central nervous system. An underlying mechanism for sympatho-excitation is thought to be oxidative stress resulting from Angiotensin II (AngII) type 1 receptor (AT1R) activation. Over the past several decades, pharmacological targeting of components of the RAAS have been used as standard therapy in CHF and HTN. However, additional therapeutic strategies are necessary to control these diseases. Oxidative stress is regulated, in part, by the …

Effect Of Ambient Temperature On Recovery Of Surgically Instrumented Sprague-Dawley Rats, Gianna Mangone

Senior Honors Projects, 2020-current

Based on current guidelines for housing rodents after surgical instrumentation, rodents may be housed at temperatures that hinder surgical recovery and cause thermal stress– room temperature (21°C) being one of them. Rodents are often housed at room temperature since this temperature is easy for humans to be caring for them. However, if recovering rodents are thermally stressed, experimental results will be confounded. To address this issue, Sprague-Dawley rats were surgically instrumented with radiotelemtry thermoprobes (Data Sciences, #TA-10F40) to monitor their core temperatures, then housed at one of five temperatures to assess the effect ambient temperature had on multiple aspects of …

Staff Training In Aquatics For Individuals With Disabilities: The Quest, Susan J. Grosse

International Journal of Aquatic Research and Education

Trained instructors in general programs have the ability and resources to initiate and follow through with developing water safe individuals who are capable swimmers. Specific staff training to prepare individuals to facilitate aquatic participation for individuals with disabilities is currently extremely limited. The purpose of this article is to examine the barriers to specialized staff training in aquatics for individuals with disabilities, to suggest necessary staff training content, and to propose topics for further research in the area of staff training. Seeking development of quality staff training programs for those working in aquatics for individuals with disabilities is the quest.

Mechanisms Of Statin Effects On Muscle And Neuronal Proteostasis, Daniel Yu

University Scholar Projects

Statins are widely prescribed and used chronically, but we know little about the effects on long-term protein homeostasis during stress and aging. Our aim was to quantify the effect of statins on stress-induced protein damage. We administered atorvastatin in a dose-response curve in Caenorhabditis elegans under naïve control conditions and in conditions of hypertonic and heat stress known to induce muscle damage measurable as countable puncta in a polyglutamine aggregation model of damage. We observed that there is significant polyglutamine aggregation variability among worms at baseline and thus further study requires within experiment baseline controls, per worm. Our results are …

Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam

Faculty and Student Publications

© 2020 Del Arco et al. Brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (PFC) and ventral tegmental area (VTA). Neurons in both regions are activated by stress and reward, and by learned cues that predict aversive or appetitive outcomes. Recent studies have proposed that separate neuronal populations and circuits in these regions encode learned aversive versus appetitive contexts. But how about the actual experience? Do the same or different PFC and VTA neurons encode unanticipated aversive and appetitive experiences? To address this, we recorded unit activity and local field …

Efficacy Of An Audio-Based Biofeedback Intervention To Modify Running Gait In Female Runners 2020, Sarah Rothstein

Master's Theses

Introduction: Gait retraining interventions are used to modify foot strike parameters associated with musculoskeletal injuries. Such interventions may prove beneficial if gait modifications are maintained long-term and provide a physiological performance benefit. Purpose: The primary purpose of this study was to determine whether female recreational runners can use a smartphone decibel app to self-modify gait mechanics associated with injury. The secondary purpose was to determine if such gait modifications are retained beyond the initial training session. The tertiary purpose was to determine if such gait modifications were associated with improved running economy. Methods: The peak vertical ground reaction force (vGRF), …

The Autoimmune System: The Effect Of Physiological Stressors On Autoantibody Glycosylation And Fidelity Of Autoantibody Profiles, Rahil Kheirkhah

Graduate School of Biomedical Sciences Theses and Dissertations

The presence of thousands of autoantibodies (aABs) in the human sera is typical, and therefore it is possible to identify an aAB profile for each individual. In the first part of this thesis, we will show the cerebrospinal fluid also exhibits an extraordinarily complex immunoglobulin G aAB profile that is composed of thousands of aABs. We show that the pattern of expression of individual aABs in CSF closely mimics that in the blood, indicative of a blood-based origin for CSF aABs. In addition, using longitudinal serum samples obtained over a span of nine years, we show remarkable stability in aAB …

The Effect Of Attentional Focus Instructions On Single Leg Balance Performance 2020., Cory Monahan

Master's Theses

Balance and postural control exercises are often a part of exercise programs. During exercise programs, movement practitioners can provide instructions to facilitate performance and learning. Instructions can be used to direct attentional focus, which has been found to affect the performance and learning of motor skills, including balance and postural control tasks. However, no known studies to date have investigated the effect of both internal and external attentional focus instructions on static single leg balance performance. The purpose of this study was to investigate the effect of attentional focus instructions on static single leg balance performance as reflected by the …