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Toxicology Commons

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Articles 31 - 60 of 67

Full-Text Articles in Toxicology

Urban Regeneration, Fall/Winter 2003, Issue 7 Sep 2019

Urban Regeneration, Fall/Winter 2003, Issue 7

Sustain Magazine

No abstract provided.


Urban Air Quality, Spring/Summer 2002, Issue 6 Sep 2019

Urban Air Quality, Spring/Summer 2002, Issue 6

Sustain Magazine

No abstract provided.


Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5 Sep 2019

Sustainability Of Industrialized Agriculture, Fall/Winter 2002, Issue 5

Sustain Magazine

No abstract provided.


Urban Design For Environmental Protection, Spring/Summer 2001, Issue 4 Sep 2019

Urban Design For Environmental Protection, Spring/Summer 2001, Issue 4

Sustain Magazine

No abstract provided.


Stream Restoration, Spring/Summer 2011, Issue 24 Sep 2019

Stream Restoration, Spring/Summer 2011, Issue 24

Sustain Magazine

No abstract provided.


Renewable Energy, Fall/Winter 2011, Issue 23 Sep 2019

Renewable Energy, Fall/Winter 2011, Issue 23

Sustain Magazine

No abstract provided.


Biodiversity, Fall/Winter 2012, Issue 25 Sep 2019

Biodiversity, Fall/Winter 2012, Issue 25

Sustain Magazine

No abstract provided.


Active Transportation, Spring/Summer 2012, Issue 26 Sep 2019

Active Transportation, Spring/Summer 2012, Issue 26

Sustain Magazine

No abstract provided.


Heat Islands, Fall/Winter 2014, Issue 29 Sep 2019

Heat Islands, Fall/Winter 2014, Issue 29

Sustain Magazine

No abstract provided.


Sustainable Behavior, Spring/Summer 2013, Issue 28 Sep 2019

Sustainable Behavior, Spring/Summer 2013, Issue 28

Sustain Magazine

No abstract provided.


Local Foods, Fall/Winter 2013, Issue 27 Sep 2019

Local Foods, Fall/Winter 2013, Issue 27

Sustain Magazine

No abstract provided.


Campus Sustainability, Spring/Summer 2014, Issue 30 Sep 2019

Campus Sustainability, Spring/Summer 2014, Issue 30

Sustain Magazine

No abstract provided.


Zero Waste, Spring/Summer 2017, Issue 36 Sep 2019

Zero Waste, Spring/Summer 2017, Issue 36

Sustain Magazine

No abstract provided.


Consent Decrees, Fall/Winter 2017, Issue 35 Sep 2019

Consent Decrees, Fall/Winter 2017, Issue 35

Sustain Magazine

No abstract provided.


Human Ecology, Spring/Summer 2016, Issue 34 Sep 2019

Human Ecology, Spring/Summer 2016, Issue 34

Sustain Magazine

No abstract provided.


Citizen Science, Fall/Winter 2016, Issue 33 Sep 2019

Citizen Science, Fall/Winter 2016, Issue 33

Sustain Magazine

No abstract provided.


Urban Streams, Spring/Summer 2015, Issue 32 Sep 2019

Urban Streams, Spring/Summer 2015, Issue 32

Sustain Magazine

No abstract provided.


Unconventional Energy, Fall/Winter 2015, Issue 31 Sep 2019

Unconventional Energy, Fall/Winter 2015, Issue 31

Sustain Magazine

No abstract provided.


Carbon Neutral, Spring/Summer 2018, Issue 38 Sep 2019

Carbon Neutral, Spring/Summer 2018, Issue 38

Sustain Magazine

No abstract provided.


Political Will, Fall/Winter 2018, Issue 37 Sep 2019

Political Will, Fall/Winter 2018, Issue 37

Sustain Magazine

No abstract provided.


Our Envirome, Spring/Summer 2019, Issue 40 Aug 2019

Our Envirome, Spring/Summer 2019, Issue 40

Sustain Magazine

No abstract provided.


Plastic Pollution, Fall/Winter 2019, Issue 39.3 Aug 2019

Plastic Pollution, Fall/Winter 2019, Issue 39.3

Sustain Magazine

No abstract provided.


Plastic Pollution, Fall/Winter 2019, Issue 39.2 Aug 2019

Plastic Pollution, Fall/Winter 2019, Issue 39.2

Sustain Magazine

No abstract provided.


Plastic Pollution, Fall/Winter 2019, Issue 39 Aug 2019

Plastic Pollution, Fall/Winter 2019, Issue 39

Sustain Magazine

No abstract provided.


Critical Physicochemical Properties For Nanoparticle Toxicity: Impact Of Surface Coating And Size On Particle-Induced Cell Transformation And Inflammatory Response, Tiffany Kornberg Jan 2019

Critical Physicochemical Properties For Nanoparticle Toxicity: Impact Of Surface Coating And Size On Particle-Induced Cell Transformation And Inflammatory Response, Tiffany Kornberg

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nanoparticles, which measure 100 nm in at least one dimension, have surged in development, production, and use for a wide range of applications. However, the rapid pace of development for these emerging materials with unclear/unknown toxicity profiles makes it difficult to adequately assess health risk associated with exposure. One critical obstacle which limits scientific research to fill these critical knowledge gaps is the lack of accurate and predictive models for nanotoxicology studies, particularly those which involve occupationally relevant exposure scenarios (pulmonary exposure to low dose of particles in the circulating air). Typically, animal models are used to assess potential systemic …


Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender May 2018

Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender

Student Theses 2015-Present

This paper aims to shed light on the dissonance caused by the superimposition of Dominant Human Systems on Natural Systems. I highlight the synthetic nature of Dominant Human Systems as egoic and linguistic phenomenon manufactured by a mere portion of the human population, which renders them inherently oppressive unto peoples and landscapes whose wisdom were barred from the design process. In pursuing a radical pragmatic approach to mending the simultaneous oppression and destruction of the human being and the earth, I highlight the necessity of minimizing entropic chaos caused by excess energy expenditure, an essential feature of systems that aim …


The Effects Of Polychlorinated Biphenyls Exposure On Non-Alcoholic Fatty Liver Disease : Role Of Aryl Hydrocarbon Receptor., Hongxue Shi May 2018

The Effects Of Polychlorinated Biphenyls Exposure On Non-Alcoholic Fatty Liver Disease : Role Of Aryl Hydrocarbon Receptor., Hongxue Shi

Electronic Theses and Dissertations

Polychlorinated biphenyls (PCBs) are detectable in serum of 100% of adults in US, and has been associated with fatty liver disease in epidemiological studies. PCBs are classified as either dioxin-like (DL) or non-dioxin-like (NDL) PCB based on their ability to activate the aryl hydrocarbon receptor (AhR). We used exposures that reflect human bioaccumulation patterns, which resembles Aroclor 1260 with a low level of the DL-PCB, PCB 126. Our aim was to determine if this exposure will activate the human and mouse AhR and examine if receptor activation influences these steatotic responses due to PCB exposures. DL-PCBs exposure-induced AhR activation in …


9-Aminoacridine Inhibits Ribosome Biogenesis And Synergizes With Cytotoxic Drugs To Induce Selective Killing Of P53-Deficient Cells, Leonid Anikin, Dimitri G Pestov Dec 2017

9-Aminoacridine Inhibits Ribosome Biogenesis And Synergizes With Cytotoxic Drugs To Induce Selective Killing Of P53-Deficient Cells, Leonid Anikin, Dimitri G Pestov

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Common cancer treatments target rapidly dividing cells and do not discriminate between cancer and normal host cells. One approach to mitigating negative side‐effects of cancer treatment is to temporarily arrest cell cycle progression and thus protect normal cells during cytotoxic treatments, a concept called cyclotherapy. We recently proposed that transient inhibition of post‐transcriptional steps of ribosome biogenesis (RBG) can be used to selectively arrest p53‐positive host cells and not p53‐null cancer cells. In this study, we investigated whether cytoprotective RBG inhibition can be achieved through small molecule treatment.


Activation Des Éosinophiles Humains Par Des Nanoparticules, Denis Girard, Maxime Marion-Murphy Nov 2017

Activation Des Éosinophiles Humains Par Des Nanoparticules, Denis Girard, Maxime Marion-Murphy

Rapports de recherche scientifique

L’économie du Canada, comme celle de bien d’autres pays industrialisés, bénéficie du développement des nanotechnologies dont le fort potentiel peut être exploité dans plusieurs secteurs industriels. Un nombre croissant d’entreprises québécoises de production de nanoparticules (NP) est d’ailleurs déjà implanté et tout porte à croire que d’autres emboîteront le pas dans les années à venir. Ce faisant, non seulement le nombre de travailleurs œuvrant dans la fabrication et la synthèse des NP augmentera sensiblement, mais également le nombre de ceux qui seront appelés à en manipuler et à en transformer dans les domaines des nanotechnologies en général. Une des conséquences …


Inhibition Of Post-Transcriptional Steps In Ribosome Biogenesis Confers Cytoprotection Against Chemotherapeutic Agents In A P53-Dependent Manner, Russell T Sapio, Anastasiya N Nezdyur, Matthew Krevetski, Leonid Anikin, Vincent J Manna, Natalie Minkovsky, Dimitri G Pestov Aug 2017

Inhibition Of Post-Transcriptional Steps In Ribosome Biogenesis Confers Cytoprotection Against Chemotherapeutic Agents In A P53-Dependent Manner, Russell T Sapio, Anastasiya N Nezdyur, Matthew Krevetski, Leonid Anikin, Vincent J Manna, Natalie Minkovsky, Dimitri G Pestov

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The p53-mediated nucleolar stress response associated with inhibition of ribosomal RNA transcription was previously shown to potentiate killing of tumor cells. Here, we asked whether targeting of ribosome biogenesis can be used as the basis for selective p53-dependent cytoprotection of nonmalignant cells. Temporary functional inactivation of the 60S ribosome assembly factor Bop1 in a 3T3 cell model markedly increased cell recovery after exposure to camptothecin or methotrexate. This was due, at least in part, to reversible pausing of the cell cycle preventing S phase associated DNA damage. Similar cytoprotective effects were observed after transient shRNA-mediated silencing of Rps19, but not …