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Articles 2701 - 2730 of 3590

Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Medical Food Formulation : Soybean Protein-Based Liquid Formula(อาหารทางการแพทย์ชนิดเหลวสูตรโปรตีนสกัดจากถั่วเหลือง), Oranong Kangsadalampai, Thitirat Panmaung, Poonsup Dangrungroj Jan 1998

Medical Food Formulation : Soybean Protein-Based Liquid Formula(อาหารทางการแพทย์ชนิดเหลวสูตรโปรตีนสกัดจากถั่วเหลือง), Oranong Kangsadalampai, Thitirat Panmaung, Poonsup Dangrungroj

The Thai Journal of Pharmaceutical Sciences

Soy protein-based liquid medical food was formulated. The formula contained 4.70 g soy protein, 3.20 g soy bean oil, 10.00 g MCT oil 1 15.30 g maltodextrin and water adjusted to 100 ml. It was homogenized, then filled in to bottle and sterilized at 121°...


A Rapid And Simple Colorimetric Assay For Screening Of Anti-Hsv Agents(วิธีการทดสอบฤทธิ์ต้านโวรัสก่อโรคเริมที่ง่ายและรวดเร็ว โดยอาศั..., Thitima Pengsuparp, Vimolmas Lipipun, Rutt Suttisri Jan 1998

A Rapid And Simple Colorimetric Assay For Screening Of Anti-Hsv Agents(วิธีการทดสอบฤทธิ์ต้านโวรัสก่อโรคเริมที่ง่ายและรวดเร็ว โดยอาศั..., Thitima Pengsuparp, Vimolmas Lipipun, Rutt Suttisri

The Thai Journal of Pharmaceutical Sciences

There are several different approaches to detect the activities of potential antiviral agents in vitro. Plaque reduction assay is one of the classical methods for determining antiviral activity that is time-consuming and needs specialized skill in order ...


An Attempt To Develop Pharmaceutical Care Guidelines In Thailand(รายงานการประชุมเชิง,ปฏิบัติการบริบาลทางเภสัขกรรม ความพยายามในการ..., Nawarut Charupatanapong, Bungorn Sripanidhkulchai, Katha Bunditanukul Jan 1998

An Attempt To Develop Pharmaceutical Care Guidelines In Thailand(รายงานการประชุมเชิง,ปฏิบัติการบริบาลทางเภสัขกรรม ความพยายามในการ..., Nawarut Charupatanapong, Bungorn Sripanidhkulchai, Katha Bunditanukul

The Thai Journal of Pharmaceutical Sciences

The purposes of this study were to develop pharmaceutical care guidelines in Thailand and encourage pharmacists in the Northeast to provide pharmaceutical care for their patients after their participation in the workshop. A two-day workshop was held at t...


Key Word Index, Author Index(ดรรชนีกุญแจคำ, ดรรชนีผู้แต่ง), N/A Jan 1998

Key Word Index, Author Index(ดรรชนีกุญแจคำ, ดรรชนีผู้แต่ง), N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Development And Evaluation Of Polymeric Matrices For Isosorbide Dinitrate Transdermal Drug Delivery Systems(การพัฒนาและการประเมิน,ผลมาทริกซ์พอลิเมอร์สำหรับ ระ..., Praneet Opanasopit, Suwannee Panomsuk, Tanasait Ngawhiranpat, Khwanta Meeoim, Jittima Suratannon, Jaroenlakana Tanikkul Jan 1998

Development And Evaluation Of Polymeric Matrices For Isosorbide Dinitrate Transdermal Drug Delivery Systems(การพัฒนาและการประเมิน,ผลมาทริกซ์พอลิเมอร์สำหรับ ระ..., Praneet Opanasopit, Suwannee Panomsuk, Tanasait Ngawhiranpat, Khwanta Meeoim, Jittima Suratannon, Jaroenlakana Tanikkul

The Thai Journal of Pharmaceutical Sciences

The polymeric matrix transdermal delivery systems were formulated using Polyvinyl alcohol (PVA), Polyvinyl pyrrolidone K30 (PVP K30), Hydroxypropylmethylcellulose (HPMC), Ethylene vinyl acetate copolymer (EVAco, vinyl acetate content 40%) as polymers. Pr...


Tyrosinase Inhibitors From Artocarpus Lakoocha(สารที่มีฤทธิ์ยับยั้งเอนไซม์ไทโรสิเนสจากมะหาด), Boonchoo Sritularak, Wanchai De-Eknamkul, Kittisak Likhitwitayawuid Jan 1998

Tyrosinase Inhibitors From Artocarpus Lakoocha(สารที่มีฤทธิ์ยับยั้งเอนไซม์ไทโรสิเนสจากมะหาด), Boonchoo Sritularak, Wanchai De-Eknamkul, Kittisak Likhitwitayawuid

The Thai Journal of Pharmaceutical Sciences

Tyrosinase is an enzyme widely distributed in nature. It has been found in plants, fungi and animals. A number of physiological functions of this enzyme have been studied. In human, its function in the biosynthesis of the skin pigment melanin is well est...


Antifungal Drug Therapy For Hiv-Infected Patients Of Bamrasnaradura Hospital(การใช้ยาต้านเชื้อราในผู้ป่วยที่ติดเชื้อ Hiv ที่โรงพยาบาลบำราศน..., Yukontorn Jirapongpitak, Sarinee Krittiyanunt, Winit Winit-Watjana Jan 1998

Antifungal Drug Therapy For Hiv-Infected Patients Of Bamrasnaradura Hospital(การใช้ยาต้านเชื้อราในผู้ป่วยที่ติดเชื้อ Hiv ที่โรงพยาบาลบำราศน..., Yukontorn Jirapongpitak, Sarinee Krittiyanunt, Winit Winit-Watjana

The Thai Journal of Pharmaceutical Sciences

HIV-infected patients are prone to opportunistic infections, especially fungal infection, which need appropriate treatment. This study is intended to examine pathogenic fungi that caused opportunistic fungal infections and the use of antifungal drugs in ...


Pharmacology Of Male Contraceptives(เภสัชวิทยาของยาคุมกำเนิดเพศชาย), Srisombat Nawanopparatsakut Jan 1998

Pharmacology Of Male Contraceptives(เภสัชวิทยาของยาคุมกำเนิดเพศชาย), Srisombat Nawanopparatsakut

The Thai Journal of Pharmaceutical Sciences

Nowadays male contraceptives begin to play an important role. However, the information about drugs that have pharmacological activity as male contraceptives is still limited. Male contraceptive drugs should be safe and provide only short-term effect. Mal...


Medical Savings Accounts, Supakit Wongwiwatthananukit Jan 1998

Medical Savings Accounts, Supakit Wongwiwatthananukit

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Inactivation Of Aminoglycosides By Penicillins And Cephalosporins(การทำให้ยาในกลุ่มอะมิโนกลัยโคซายด์หมดฤทธิ์ โดยยาในกลุ่มเพนนิซิล..., Jinda Wangboonskul, Aporanee Chaiyakum, Tanee Tetsiri Jan 1998

Inactivation Of Aminoglycosides By Penicillins And Cephalosporins(การทำให้ยาในกลุ่มอะมิโนกลัยโคซายด์หมดฤทธิ์ โดยยาในกลุ่มเพนนิซิล..., Jinda Wangboonskul, Aporanee Chaiyakum, Tanee Tetsiri

The Thai Journal of Pharmaceutical Sciences

Faculty of Pharmaceutical Sciences, Khon Kaen University has provided a therapeutic drug monitoring service for Srinagarind Hospital since 1994. However, The service is only available on the working-hour basis. Some submitted samples, therefore, have to ...


Study Of Cardiovascular Activity Of Morinda Citrifolia Fruits(การศึกษาฤทธิ์ของผลยอต่อระบบหัวใจและหลอดเลือด), Uraiwan Permpipat, Puntarika Na Pattaloong Jan 1998

Study Of Cardiovascular Activity Of Morinda Citrifolia Fruits(การศึกษาฤทธิ์ของผลยอต่อระบบหัวใจและหลอดเลือด), Uraiwan Permpipat, Puntarika Na Pattaloong

The Thai Journal of Pharmaceutical Sciences

We previously showed that Morinda citrifolia fruits possess weak anti-dopaminergic activity which may account for its antiemetic activity as recommended in Thai traditional medicine. In this study we examined cardiovascular activity of M. citrifolia to d...


Searching The Internet For Drug Information(การสิบค้นข้อมูลยาบนอินเตอร์เนต), Wanchai Treyaprasert Jan 1998

Searching The Internet For Drug Information(การสิบค้นข้อมูลยาบนอินเตอร์เนต), Wanchai Treyaprasert

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Monoterpene Glycosides And Furan Derivative From Coleus Amboinicus Lour.(โมโนเทอร์ปีนกลัยโคใซด์และอนุพันธ์ฟูรานจากเนียมหูเสือ), Rutt Suttisri, Ratiphan Laungsuwon Jan 1998

Monoterpene Glycosides And Furan Derivative From Coleus Amboinicus Lour.(โมโนเทอร์ปีนกลัยโคใซด์และอนุพันธ์ฟูรานจากเนียมหูเสือ), Rutt Suttisri, Ratiphan Laungsuwon

The Thai Journal of Pharmaceutical Sciences

Extraction of the aerial parts of Coleus amboinicus Lour, yielded two monoterpene glycosides, thymoquinol-P-D-glu copyranoside and carvacrol-p-D -glucopyranoside, and a furan derivative, 5 - (hydroxymethyl)-2-furaldehyde. Identification of the compounds ...


Chemical Stability And Mechanism Of Degradation Of Omeprazole In Solution(ความคงตัวทางเคมีและกลไกการเสื่อมสลายของโอมิปราโซลใน สารละลาย), Narong Sarisuta, Tudsong Tourtip, Siripote Chuarcharoern Jan 1998

Chemical Stability And Mechanism Of Degradation Of Omeprazole In Solution(ความคงตัวทางเคมีและกลไกการเสื่อมสลายของโอมิปราโซลใน สารละลาย), Narong Sarisuta, Tudsong Tourtip, Siripote Chuarcharoern

The Thai Journal of Pharmaceutical Sciences

The chemical stability and kinetics of omeprazole in buffer solutions at various pH values, 5.0, 7.0, 8.0, and 10.0, were studied at three different stress conditions, 25, 40, and 50 °c. It was found that the degradation reaction followed the pseudo fir...


Abstracts From The 15th Pharmaceutical Science Meeting Faculty Of Pharmaceutical Sciences, Chulalongkorn University, N/A Jan 1998

Abstracts From The 15th Pharmaceutical Science Meeting Faculty Of Pharmaceutical Sciences, Chulalongkorn University, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Microencapsulation Of Lemon Oil By Spray Drying Using Acacia And Maltodextrin(ไมโครเอนแคปซูเลชันของน้ำมันผิวมะนาวด้วยการพ่นแห้ง โดยใช้อเค..., Pienkit Dangprasirt, Sansanee Pongwai Jan 1998

Microencapsulation Of Lemon Oil By Spray Drying Using Acacia And Maltodextrin(ไมโครเอนแคปซูเลชันของน้ำมันผิวมะนาวด้วยการพ่นแห้ง โดยใช้อเค..., Pienkit Dangprasirt, Sansanee Pongwai

The Thai Journal of Pharmaceutical Sciences

The use of spray drying as a method of preparing microcapsule powder from lemon oil was studied. Acacia and maltodextrin were used as filmogenic and protective agents in preparing lemon oil microcapsule, respectively. Various ratios of acacia:maltodextri...


Determination Of Constituents, Stability And Antifungal Activities Of Betel Leaf Oil(การศึกษาองค์ประกอบทางเคมีและความคงตัวของน้ำมันพลู กับฤทธิ..., N. Suwanpidokkul, V. Chantarateptawan, Y. Boonpooh, P. Thaunsukon, K. Kraisintu Jan 1998

Determination Of Constituents, Stability And Antifungal Activities Of Betel Leaf Oil(การศึกษาองค์ประกอบทางเคมีและความคงตัวของน้ำมันพลู กับฤทธิ..., N. Suwanpidokkul, V. Chantarateptawan, Y. Boonpooh, P. Thaunsukon, K. Kraisintu

The Thai Journal of Pharmaceutical Sciences

Betel leaf oil distilled from freshly collected leaves by our laboratory was compared with similar oil obtained from the Faculty of Pharmaceutical Sciences, Chulalonglorn University using GC-MS. Forty four compounds were identified, and both oil samples ...


Immunomodulating Activity Of Derris Scandens Benth.(การศึกษาฤทธิ์กระตุ้นภูมิคุ้มกันของเถาวัลย์เปรียง), Anchalee Chuthaputti, Pranee Chavalittumrong Jan 1998

Immunomodulating Activity Of Derris Scandens Benth.(การศึกษาฤทธิ์กระตุ้นภูมิคุ้มกันของเถาวัลย์เปรียง), Anchalee Chuthaputti, Pranee Chavalittumrong

The Thai Journal of Pharmaceutical Sciences

According to the Thai traditional medicine, Derris scandens Benth. stem is used for the relieve of muscle ache or pain, as a diuretic, expectorant and antitussive. Since Derris scandens is one of the most commonly used medicinal plants in Thailand and it...


Diphtheria Toxin Fusion Proteins, Frank Foss, Mansoor Saleh, James Krueger, John Nichols, John Murphy Jan 1998

Diphtheria Toxin Fusion Proteins, Frank Foss, Mansoor Saleh, James Krueger, John Nichols, John Murphy

Haematology and Oncology, East Africa

Two different approaches have been undertaken to develop targeted biomolecules for therapeutics. The first was the construction of immunotoxins consisting of monoclonal antibodies chemically linked through a disulfide bond to a plant or bacterial toxin or radionuclide. Instability of the chemical conjugation of some of the earlier immunotoxins led to the concept of using protein engineering and recombinant DNA to assemble fusion genes combining the sequences for the enzymatically active and translocation domains of a toxin with those of a specific targeting ligand. From the outset, the prospect of using recombinant DNA methods to assemble the structural genes encoding bacterial …


Comparison Of Beta-Adrenoceptor Coupled Camp Production In Cultured Human Mononuclear Leukocytes And Myometrial Cells, Yu-Li Liu Dec 1997

Comparison Of Beta-Adrenoceptor Coupled Camp Production In Cultured Human Mononuclear Leukocytes And Myometrial Cells, Yu-Li Liu

Electronic Theses and Dissertations

$\beta\sb2$-Adrenoceptor ($\beta\sb2$-AR) agonists, such as terbutaline, are used as tocolytic agents in the treatment of preterm labor. $\beta$-Adrenoceptor stimulation relaxes myometrium through specific receptors coupled through Gs to adenylyl cyclase (AC) that catalyzes the conversion of ATP to cAMP. The purpose of this study was to compare $\beta$-adrenoceptors and cAMP production in cultured human leukocytes and myometrial cells, and to determine the importance of $\beta$-adrenoceptors and cAMP production in isoproterenol-induced myometrial relaxation. $\sp{125}$I-iodopindolol was used to assess $\beta$-adrenoceptor affinity and number cAMP levels were analyzed before and after stimulation by isoproterenol, AlF$\sb4\sp-$, forskolin, and PGE$\sb1$. Isometric recording was used to …


Effects Of Lipoproteins On Cyclo-Oxygenase And Lipoxygenase Pathways In Human Platelets, S A. Saeed, R A. Memon, A H. Gilani, B H. Shah Mar 1997

Effects Of Lipoproteins On Cyclo-Oxygenase And Lipoxygenase Pathways In Human Platelets, S A. Saeed, R A. Memon, A H. Gilani, B H. Shah

Department of Biological & Biomedical Sciences

The products of arachidonic acid (AA) metabolism in platelets play an important role in platelet shape change, adhesion and aggregation which may participate in the pathogenesis of ischemic heart disease and thrombosis. Since lipoproteins are also involved in the pathogenesis of thrombo-embolic disorders, the effect of human lipoproteins (HDL, LDL, VLDL) on AA metabolism in human platelets was investigated. Lipoproteins were separated by density gradient zonal ultracentrifugation. The effects of lipoproteins on production of AA metabolites in human platelets i.e., thromboxane A2 (TXA2) and hydroxy-eicosatetraenoic acids (HETEs) were examined using radiometric thin layer chromatography coupled with automated data integrator system. …


A Search For The Cause Of Excess Thiol Sensitivity In A Mutant Of Escherichia Coli, Hongying Zeng Mar 1997

A Search For The Cause Of Excess Thiol Sensitivity In A Mutant Of Escherichia Coli, Hongying Zeng

Loma Linda University Electronic Theses, Dissertations & Projects

The subject of this study was a search for the biochemical basis of hypersensitivity to thiols in a mutant of Escherichia coli (IS16). A 1.3 kb chromosomal fragment from E. coli (introduced into the mutant on a plasmid) successfully abolished the hypersensitivity. This fragment contained only one intact gene, ubiX, which codes for polyprenyl-4-hydroxybenzoatelyase. The decarboxylation of octaprenyl-4- hydroxybenzoate in E. coli is catalyzed not only by the ubiX protein but also by the product of ubiD. The ubiquinone content of IS16 was only 2% of that of its parent strain, while the complementing plasmid increased it …


Colonic Drug Delivery : Study And Strategy(การนำส่งยาทางลำไส์ใหญ่ : การศึกษาและกลยุทธ์การนำส่ง), Thawatchai Phaechamud Jan 1997

Colonic Drug Delivery : Study And Strategy(การนำส่งยาทางลำไส์ใหญ่ : การศึกษาและกลยุทธ์การนำส่ง), Thawatchai Phaechamud

The Thai Journal of Pharmaceutical Sciences

Many investigators have designed oral preparations to deliver compounds to human colon. The colon provides somewhat less hostile environments with lesser diversity and intensity o f enzymatic activities as compared to the stomach and the small intestine....


Kinetics Of Drug Loading Onto Cation-Exchange Resins And Effect Of Concurrent Counter-Ions, Prasert Akkaramongkolporn Jan 1997

Kinetics Of Drug Loading Onto Cation-Exchange Resins And Effect Of Concurrent Counter-Ions, Prasert Akkaramongkolporn

The Thai Journal of Pharmaceutical Sciences

The patterns of chlorpheniramine loading onto cation-exchange resins with and without concurrent counter-ions were investigated. All of them were found to give the best fit with the model according to film diffusion-controlled process. The existence of c...


Prevention Action Of Turmeric Against Hcl-Induced Gastric Necrosis In Rat : To Verify The Mode Of Action Of Previous Clinical Study, Ch. Prucksunand, N. Kiatying-Aiigsulee, K. Sawasdimongkol, S. Wimolwattanapun, B. Petchruengrong, K. Tiensong, S. Paeyai Jan 1997

Prevention Action Of Turmeric Against Hcl-Induced Gastric Necrosis In Rat : To Verify The Mode Of Action Of Previous Clinical Study, Ch. Prucksunand, N. Kiatying-Aiigsulee, K. Sawasdimongkol, S. Wimolwattanapun, B. Petchruengrong, K. Tiensong, S. Paeyai

The Thai Journal of Pharmaceutical Sciences

The purposes of this scientific work were to study the mode of action of turmeric in animal and to verify previous clinical data of turmeric action in peptic ulcer patient. Oral administration of 0.6 N HC1 to fasted rats produced extensive necrosis of ga...


Application Of Factorial Design In Development Of Hydrochlorothiazide Tablet Formulation(การใซ Factorial Design ใน การพัฒนาตำรับยาเม็ด ไฮโดรคลอโรใธอาใซด์), Pienkit Dangprasirt, Sansanee Pongwai Jan 1997

Application Of Factorial Design In Development Of Hydrochlorothiazide Tablet Formulation(การใซ Factorial Design ใน การพัฒนาตำรับยาเม็ด ไฮโดรคลอโรใธอาใซด์), Pienkit Dangprasirt, Sansanee Pongwai

The Thai Journal of Pharmaceutical Sciences

A two-level full factorial experimental design was applied to study the influences of various tabletting process variables on the properties of hydrochorothiazide (HCTZ) tablets prepared by direct compression and wet granulation. Sixteen HCTZ tablet form...


The State Of The Thai National Drug Policy : An Indicator Analysis, Sauwakon Ratanawijitrasin, Pompis Silkavute Jan 1997

The State Of The Thai National Drug Policy : An Indicator Analysis, Sauwakon Ratanawijitrasin, Pompis Silkavute

The Thai Journal of Pharmaceutical Sciences

This paper reports key concepts and findings of an indicator study of the Thai National Drug Policy. This study is a part of the “Comparative Analysis of National Drug Policies” Project, which was carried out in 12 countries. Eighty-three standardize...


Physical Properties And Release Characteristics Of Matrices Prepared From Co-Spray Dried Powders Of Propranolol Hydrochloride And Chitosan, Poj Kulvanich, Sasitom Prugmahachaikul, Krisana Kraisintu Jan 1997

Physical Properties And Release Characteristics Of Matrices Prepared From Co-Spray Dried Powders Of Propranolol Hydrochloride And Chitosan, Poj Kulvanich, Sasitom Prugmahachaikul, Krisana Kraisintu

The Thai Journal of Pharmaceutical Sciences

Chitosan was prepared by deacetylation of chitin from shrimp hulls at various reaction times to yield chitosans having different degrees of deacetylation. Chitosans obtained were employed to prepare co-spray dried powders of propranolol hydrochloride-chi...


Xerostomia And Management(โรคน้ำลายแห้งและการดูแลรักษา), Chantana Aromdee Jan 1997

Xerostomia And Management(โรคน้ำลายแห้งและการดูแลรักษา), Chantana Aromdee

The Thai Journal of Pharmaceutical Sciences

Xerostomia is a dried mouth symptom caused by salivary gland dysfunction. The major causes are inflammation or atrophy of the salivary glands, side effects of some drugs or some psychological factors. The inflammation or atrophy of salivary glands is usu...


Hypoglycemic Activity Of Tridaxprocumbens Linn, In Rats(ฤทธิ์ของตีนตุ๊กแก ( Tridax Procumbens Linn.) ในการลดระดับนํ้าตาลในเลือดของหนูขาว), Kalaya Anulukanapakom, Orasa Pancharoen, Uraiwan Permpipat Jan 1997

Hypoglycemic Activity Of Tridaxprocumbens Linn, In Rats(ฤทธิ์ของตีนตุ๊กแก ( Tridax Procumbens Linn.) ในการลดระดับนํ้าตาลในเลือดของหนูขาว), Kalaya Anulukanapakom, Orasa Pancharoen, Uraiwan Permpipat

The Thai Journal of Pharmaceutical Sciences

In the Northeastern Thailand, an aqueous extract of a mixture of Tridax procumbens Linn. and Euphorbia hirta Linn, is taken orally to treat diabetes mellitus. In the present study, 95% ethanolic extract of T. procumbens (TP-1) was tested for hypoglycemic...