Neuroscience and Neurobiology Commons^™

Theta Activity During Navigation In Virtual Environments, Colleen Margaret Moore

Psychology Theses & Dissertations

Human navigation has gone through many different stages, from guidance by stars to guidance by technology. Theories for performance differences range from differences between individuals, to experience with the environment. Researchers turn to virtual environments during experimentation which are easy to manipulate and easier to measure during navigation. However, fidelity is an issue with regard to transfer of learning to a real world environment. We examined differences in theta activity during navigation in low and high fidelity virtual environments. The researchers recruited thirty-two students between the ages of 18-40 from the university subject pool for voluntary participation. We measured EEG …

The Neural Substrates Of Infant Sleep In Rats, Karl Æ. Karlsson, Andrew J. Gall, Ethan J. Mohns, Adele M. H. Seelke, Mark S. Blumberg

Faculty Publications

Sleep is a poorly understood behavior that predominates during infancy but is studied almost exclusively in adults. One perceived impediment to investigations of sleep early in ontogeny is the absence of state-dependent neocortical activity. Nonetheless, in infant rats, sleep is reliably characterized by the presence of tonic (i.e., muscle atonia) and phasic (i.e., myoclonic twitching) components; the neural circuitry underlying these components, however, is unknown. Recently, we described a medullary inhibitory area (MIA) in week-old rats that is necessary but not sufficient for the normal expression of atonia. Here we report that the infant MIA receives projections from areas containing …

Daily Rhythm Of Cerebral Blood Flow Velocity, Deirdre A. Conroy, Arthur J. Spielman, Rebecca Q. Scott

Publications and Research

Background: CBFV (cerebral blood flow velocity) is lower in the morning than in the afternoon and evening. Two hypotheses have been proposed to explain the time of day changes in CBFV: 1) CBFV changes are due to sleep-associated processes or 2) time of day changes in CBFV are due to an endogenous circadian rhythm independent of sleep. The aim of this study was to examine CBFV over 30 hours of sustained wakefulness to determine whether CBFV exhibits fluctuations associated with time of day.

Methods: Eleven subjects underwent a modified constant routine protocol. CBFV from the middle cerebral artery was monitored …

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

The Temporal Context Model In Spatial Navigation And Relational Learning: Toward A Common Explanation Of Medial Temporal Lobe Function Across Domains, Marc W. Howard, Mrigankka S. Fotedar, Aditya V. Datey, Michael E. Hasselmo

Psychology - All Scholarship

The medial temporal lobe (MTL) has been studied extensively at all levels of analysis, yet its function remains unclear. Theory regarding the cognitive function of the MTL has centered along 3 themes. Different authors have emphasized the role of the MTL in episodic recall, spatial navigation, or relational memory. Starting with the temporal context model (M.W. Howard and M. J. Kahana, 2002), a distributed memory model that has been applied to benchmark data from episodic recall tasks, the authors propose that the entorhinal cortex supports a gradually changing representation of temporal context and the hippocampus proper enables retrieval of these …

Using Distributed Network Systems To Model Perception With An Artificial Neural Network, Tide Kansona Takizala

All-Inclusive List of Electronic Theses and Dissertations

It is difficult to be certain about brain functioning. Until now, most efforts to understand brain computations have only been conducted on a stand alone computer. In order to recreate the brain accurately, members of the Institute of Cognitive Computing Technology (ICCT) were interested in finding out whether or not a biological process could be simulated on a Distributed Artificial Neural Network (DANN). The goal of this investigation was to implement visual perception on a network of computers and compare the computations of the network with those of a human brain. The distributed network was developed as a Local Area …

Event-Related Potential Evidence For Multiple Causes Of The Revelation Effect, P. Andrew Leynes, Joshua Landau, Jessica Walker, Richard J. Addante

Psychology Faculty Publications

Asking people to discover the identity of a recognition test probe immediately before making a recognition judgment increases the probability of an old judgment. To inform theories of this “revelation effect,” event-related potentials (ERPs) were recorded for revealed and intact test items across two experiments. In Experiment 1, we used a revelation effect paradigm where half of the test probes were presented as anagrams (i.e., a related task) and the other items were presented intact. The pattern of ERP results from this experiment suggested that revealing an item decreases initial familiarity levels and caused the revealed items to elicit similar …

Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine

Psychology Faculty Publications

Exposure to stress during gestation results in physiological and behavioral alterations that persist into adulthood. This study examined the effects of prenatal stress on the postnatal expression of sexually differentiated cognitive, hormonal, and neurochemical profiles in male and female rats. Pregnant dams were subjected to restraint stress three times daily for 45 min during d 14-21 of pregnancy. The offspring of control and prenatally stressed dams were tested for anxiety-related and cognitive behaviors, stress and gonadal steroid hormone levels, as well as monoamines and metabolite levels in selected brain regions. Postnatal testosterone levels (measured at 1 and 5 d) did …

Enhanced Operant Self-Administration Of Alcohol In Wistar Rats Receiving Intermittent Versus Continuous Alcohol Vapor Exposure, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Radiation Effects On Dopamine-Mediated Prepulse Inhibition In The C57bl/6 Mouse, Cara Nicole Zuccarelli Miller

Loma Linda University Electronic Theses, Dissertations & Projects

This study examined the effects of proton and gamma radiation on a dopamine-dependent sensory gating mechanism: prepulse inhibition of the startle reflex. The purpose of this research was to describe potential hazards of proton radiation to the central nervous system in long-term space fight and for proton therapy patients. Results from previous research indicate that startle behavior is modified by proton and iron radiation. Forty-eight 10-½ week old, male C57BL/6 mice were used to characterize the optimal parameters for the model (prepulse duration, probe duration, and stimulus-onset-asynchrony). Three hundred and fifty two mice were used to characterize the time course …

A Research Agenda For Political Personality And Leadership Studies: An Evolutionary Proposal, Aubrey Immelman, Theodore Millon

Psychology Faculty Publications

Despite major neuroscientific advances in the past two decades and parallel conceptual refinement in evolutionary theory, personality-in-politics inquiry remains adrift, divorced from these broader spheres of scientific knowledge. This paper reviews the neurobiological substrates of three major domains of evolutionary biology and behavioral ecology relevant to political personality assessment and the psychological examination of political leaders; furnishes a context and set of guiding ideas to revitalize the study of the person as biopsychosocial entity in politics; advances a generative theory of personality and political leadership performance; and proposes an agenda for advancing personality-in-politics and leadership inquiry, informed by insights derived …

Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Gamma Oscillations Correlate With Working Memory Load In Humans, Marc W. Howard, Daniel S. Rizzuto, Jeremy B. Caplan, Joseph R. Madsen, John Lisman

Psychology - All Scholarship

Functional imaging of human cortex implicates a diverse network of brain regions supporting working memory—the capacity to hold and manipulate information for short periods of time. Although we are beginning to map out the brain networks supporting working memory, little is known about its physiological basis. We analyzed intracranial recordings from two epileptic patients as they performed a working memory task. Spectral analyses revealed that, in both patients, gamma (30-60 Hz) oscillations increased approximately linearly with memory load, tracking closely with memory load over the course of the trial. This constitutes the first evidence that gamma oscillations, widely implicated in …

Trends. Terrorist Brains, Ibpp Editor

International Bulletin of Political Psychology

This Trends article discusses the construct of biological reductionism in the context of the case of Red Army Faction member Ulrike Meinhof. For the author, overly emphasizing the biological aspects of Ms. Meinhof’s case might obscure legitimate grievances, and ultimately, lead to more cases of violence associated with terrorism.

Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.

Leader In Love Ii, Ibpp Editor

International Bulletin of Political Psychology

This article continues the analysis of the political consequences of leaders in love.

Law And The Biology Of Rape: Reflections On Transitions, Owen D. Jones

Vanderbilt Law School Faculty Publications

This Article serves is a sequel to a previous Article: Sex, Culture, and the Biology of Rape: Toward Explanation and Prevention, 87 Cal. L. Rev. 827 (1999). Part I briefly considers the threshold question: why consider the behavioral biology of sexual aggression at all? Part II proposes that the first step in transitioning to a more accurate and more useful model of rape behavior is to avoid a number of common definitional ambiguities that plague most rape discussions. Because those ambiguities are particularly likely to foster misunderstandings about biobehavioral perspectives, Part II also clarifies the scope of what biobehavioral theories …