Biology Commons^™

Fourier Analysis Of Phase Resetting Curves Of Neural Oscillators, Robert A. Raidt, Sorinel A. Oprisan

Journal of the South Carolina Academy of Science

We investigated the impact of changes in biologically relevant control parameters, such as the shape of an external perturbation or the conductance values of an individual model neuron, on the shape of the phase resetting curve (PRC) of that neuron. For that purpose, PRCs were generated for groups of Morris-Lecar (ML) model neurons with different conductance values but similar firing periods (within 0.005ms) using external rectangular, triangular, or trapezoidal perturbations of varying areas. These PRCs were numerically described and analyzed as a series of coefficient values using a Fourier Discrete Sine Transform (DST). We found that changes in the shape …

Development And Application Of A Gis-Based Long Island Sound Eelgrass Habitat Suitability Index Model, Jamie M.P. Vaudrey, Justin Eddings, Christopher Pickerell, Lorne Brousseau, Charles Yarish

Department of Marine Sciences

The primary objectives of the Eelgrass Habitat Suitability Index Model (EHSI Model) are to assist in the evaluation of sites being considered for eelgrass restoration efforts in the Long Island Sound (LIS) area and to identify areas where water quality issues reduce or eliminate the potential for natural eelgrass colonization. To achieve this goal, geospatial processing of data available from the Long Island Sound area was conducted using ArcGIS v10.0 including the 3D Analyst and Spatial Analyst extensions. The result is a series of maps presented in this report and a GIS-based model available for users to interact with the …

Identification Of Disulfide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1, Morgan E. Roberts, Jacquelyn P. Crail, Megan M. Laffoon, William G. Fernandez, Michael A. Menze, Mary E. Konkle

Faculty Research & Creative Activity

MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation. MitoNEET forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator. Proteomic analysis identified the specific cysteine residues that participate in the disulfide bond. This is the first report that effectively links mitoNEET to activation of the insulin regulator GDH1.

Ua66 Ogden College Of Science & Engineering Newsletter, Cheryl Stevens, Dean

Ogden College of Science & Engineering Publications

No abstract provided.

Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1, Morgan E. Roberts, Jacquelyn P. Crail, Megan M. Laffoon, William G. Fernandez, Michael A. Menze, Mary E. Konkle

Faculty Research & Creative Activity

MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation. MitoNEET forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator. Proteomic analysis identified the specific cysteine residues that participate in the disulfide bond. This is the first report that effectively links mitoNEET to activation of the insulin regulator GDH1.

Spread Of Malicious Objects In Computer Network: A Fuzzy Approach, Bimal K. Mishra, Apeksha Prajapati

Applications and Applied Mathematics: An International Journal (AAM)

We propose an e-epidemic fuzzy SEIQRS (Susceptible-Exposed-Infectious-Quarantine- Recovered-Susceptible) model for the transmission of malicious codes in a computer network. We have simulated the result for various parameters and analyzed the stability of the model. The efficiency of antivirus software and crashing of the nodes due to attack of malicious code is analyzed. Furthermore, initial simulation results illustrate the behavior of different classes for minimizing the infection in a computer network. It also reflects the positive impact of anti-virus software on malicious code propagation in a computer network. The basic reproduction number R0 f and its formulation is also discussed.

Grayscale-Image Encryption Using Random Hill Cipher Over Sln(F) Associated With Discrete Wavelet Transformation, D. C. Mishra, R. K. R. K. Sharma

Applications and Applied Mathematics: An International Journal (AAM)

Image data are highly sensitive and prone to incidental decoding by intruders. The security of image data in an insecure network is therefore a major issue. In this paper, we have presented a novel approach for grayscale-image encryption and decryption using Random Hill cipher over SLn(F) associated with discrete wavelet transformation. Earlier techniques for encryption and decryption of image data discussed missing the keys, but in this approach, both the keys and the arrangement of RHC are emphasized. Additionally, keys multiplication side (pre or post) over a grayscale-image data matrix also inevitable to know, to correctly decrypt the encrypted image …

Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1., Morgan Roberts, Jacquelyn Crail, Megan Laffoon, William Fernandez, Michael Menze, Mary Konkle

Faculty and Staff Scholarship

MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation. MitoNEET forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator. Proteomic analysis identified the specific cysteine residues that participate in the disulfide bond. This is the first report that effectively links mitoNEET to activation of the insulin regulator GDH1.

The Two-Phase Arterial Blood Flow With Or Without A Catheter And In The Presence Of A Single Or Multi Stenosis, Ani E. Garcia, Daniel N. Riahi

Applications and Applied Mathematics: An International Journal (AAM)

We consider the problem of blood flow in an artery with or without a catheter and in the presence of single or multi stenosis whose shape is based on the available experimental data for the stenosis in a human’s artery. The presence of stenosis in the artery, which locally narrows portion of the artery, can be a result of fatty materials such as cholesterol in the blood. The use of catheter is important as a standard tool for diagnosis and treatment in patience whose blood flow passage in the artery is affected adversely by the presence of the stenosis within …

Numerical Solution Of Fuzzy Arbitrary Order Predator-Prey Equations, Smita Tapaswini, S. Chakraverty

Applications and Applied Mathematics: An International Journal (AAM)

This paper seeks to investigate the numerical solution of fuzzy arbitrary order predator-prey equations using the Homotopy Perturbation Method (HPM). Fuzziness in the initial conditions is taken to mean convex normalised fuzzy sets viz. triangular fuzzy number. Comparisons are made between crisp solution given by others and fuzzy solution in special cases. The results obtained are depicted in plots and tables to demonstrate the efficacy and powerfulness of the methodology.

Assessing Growth Response To Climate Controls In A Great Basin Artemisia Tridentata Plant Community, Lorenzo F. Apodaca

UNLV Theses, Dissertations, Professional Papers, and Capstones

An assessment of the growth response of key vegetative species to climatic variability is vital to identifying possible local impacts on ecosystems faced with imminent climate change. With current climate projections in Nevada predicting a shift to an even more arid climate with greater year-to-year variability, the imperative exists to identify the effects of specific climatic controls on plant growth and to research methods to assess large-scale vegetative changes, especially in more remote areas where readily available data sets may be lacking. This study utilized annual growth ring indices constructed from big sagebrush (Artemisia tridentatassp.tridentata) stems collected in Spring Valley, …

Lipid Production By Microalgae Treating Municipal Wastewater, James Edward Kelley

Master's Theses

Microalgae hold much promise as a feedstock in liquid biofuel production. Lipid content of microalgae cells range from 30-80% dry weight of biomass. It is projected that microalgae can produce between 1,000-6,500 gallons/acre/year of oil. Currently, production of industrial algae operates in open raceway ponds that use minimal capital and energy inputs to culture algae. Raceway ponds can also be used to grow microalgae from municipal waste streams. Although high biomass productivity can be achieved in these systems, there remains a large production gap between large volumes of biomass cultivation and high lipid content from microalgae cells. Low lipid content …

The Influence Of Hydrogeomorphology, Soil Redox Conditions, And Salinity On The Spatial Zoning Of Saltgrass, Salt Rush, And Cattails In Scotts Creek Marsh, Swanton Pacific Ranch, Ca, Mark D. Gormley

Master's Theses

Scotts Creek Marsh (SCM) is a small coastal wetland ecosystem in Davenport, CA. The vegetation of SCM is dominated by three halophytic zones comprised of saltgrass, salt rush, cattails. The objectives of the study were (i) to investigate the variables that influence the zoning of the three dominant halophyte communities in SCM and (ii) to the test the effectiveness of Indicator of Reduction in Soil (IRIS) tubes to indicate the reduction of S. The study examined the following parameters from April 6 to July 21, 2013: (i) the HGM of Scotts Creek Marsh, (ii) soil oxidation and reduction (redox) conditions, …

A Survey Of Heavy Metals In Water, Soil And The Surrounding Plants In The Lower Rio Grande Valley, Erving W. Morelius

Theses and Dissertations - UTB/UTPA

Heavy metal pollution of the environment in recent years has become a major issue of importance for both human and environmental health. Samples were investigated for the potential pollution of the area as it is a vital produce producing area. During the study plant, soil and water samples were collected from the Donna Reservoir and Canal System to test the concentration of various heavy metals. The heavy metals tested included both potentially toxic and micronutrients in the samples which included arsenic, cadmium, chromium, copper, iron, lead, nickel and sulfur. During the study, a sixty day sampling period was used to …

Rigidity Analysis Of Protein Biological Assemblies And Periodic Crystal Structures, Filip Jagodzinski, Pamela Clark, Jessica Grant, Tiffany Liu, Samantha Monastra, Ileana Streinu

All Faculty Scholarship for the College of the Sciences

Background

We initiate in silico rigidity-theoretical studies of biological assemblies and small crystals for protein structures. The goal is to determine if, and how, the interactions among neighboring cells and subchains affect the flexibility of a molecule in its crystallized state. We use experimental X-ray crystallography data from the Protein Data Bank (PDB). The analysis relies on an effcient graph-based algorithm. Computational experiments were performed using new protein rigidity analysis tools available in the new release of our KINARI-Web server http://kinari.cs.umass.edu.

Results

We provide two types of results: on biological assemblies and on crystals. We found that when only isolated …

Evaluating The Efficacy Of Land Snail Survey Techniques In Hawaii: Implications For Conservation Throughout The Pacific, Torsten Durkan, Norine Yeung, Wallace Meyer, Kenneth Hayes, Robert Cowie

Department of Biology Faculty Publications

Terrestrial micromolluscs (snails with an adult maximum shell dimension <5 mm) constitute a considerable proportion of the land snail fauna of the Pacific. However, micromolluscs are often underestimated in biological surveys because of size bias. It has been argued that visual searches are preferable on Pacific islands because: (1) size biases are limited based on the understanding that most native Pacific island land snails are very small, and (2) amount of labor is less than other methods such as soil surveys and adequate for inventory purposes (though not for abundance assessments). To test whether visual surveys and soil surveys were accurately recording all taxa, land snail inventories were completed in three forest reserves (5 sampling sites in each) on the island of Oahu, Hawaii. Visual surveys involved 30-min visual search in a 10 m2 site; soil surveys involved sieving leaf litter and topsoil from four 0.3 m2 quadrats and extracting snails with the aid of a microscope. The data indicate a size and microhabitat bias associated with both techniques. Visual surveys consistently collected large arboreal and litter-dwelling species but missed a significant portion of micromolluscs, while soil surveys collected micromolluscs but missed larger snails. Because of such biases, employing both methods is critical for collecting all taxa at a survey location. As such, we recommend that future land snail surveys on Pacific Islands incorporate both survey techniques. Obtaining a complete inventory is critical if we are to understand species distributions and patterns of diversity and make well-informed conservation recommendations.

A Conservation And Rigidity Based Method For Detecting Critical Protein Residues, Bahar Akbal-Delibas, Filip Jagodzinski, Nurit Haspel

All Faculty Scholarship for the College of the Sciences

Background

Certain amino acids in proteins play a critical role in determining their structural stability and function. Examples include flexible regions such as hinges which allow domain motion, and highly conserved residues on functional interfaces which allow interactions with other proteins. Detecting these regions can aid in the analysis and simulation of protein rigidity and conformational changes, and helps characterizing protein binding and docking. We present an analysis of critical residues in proteins using a combination of two complementary techniques. One method performs in-silico mutations and analyzes the protein's rigidity to infer the role of a point substitution to Glycine …

Acquisition Of An Electrochemical System Instrument For The Development Of Sensors, Elmer-Rico E. Mojico

Cornerstone 1 Reports : Expansion and Enhancements of the Thinkfinity Platform

No abstract provided.

A Multi-Scale Analysis Of The Effects Of Local- And Landscape-Level Variables On Nuthatch Occupancy And Distribution, Jesse Wood

Earth and Environmental Sciences Presentations

The objectives of this study are to conduct a multi-scale analysis of the effects of habitat variables on Brownheaded Nuthatch (S. pusilla) occupancy and spatial distribution in the greater Greenville area of South Carolina. By understanding the local- and landscape-drivers of an ecologically sensitive species, we can build a predictive model of species occurrence and contribute to regional conservation efforts of both habitat and biodiversity.

Efektivitas Sekolah Menengah Kejuruan Berstandar Iso 9001:2008 Terhadap Pencapaian Standar Isi, Standar Proses, Dan Standar Kompetensi Lulusan, Yeni Ratih Pratiwi

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk mengetahui perbedaan efektivitas pencapaian standar isi, standar proses, dan standar kompetensi lulusan pada Sekolah Menengah Kejuruan (SMK) yang telah menerapkan standar mutu ISO 9001:2008 dan SMK yang belum menerapkannya, baik pada sekolah negeri maupun swasta. Pengumpulan data dilakukan menggunakan kuesioner tertutup dengan skala Likert. Analisis data menggunakan uji ANOVA satu arah dengan bantuan program SPSS. Hasil penelitian menunjukkan bahwa terdapat perbedaan efektivitas antara SMK negeri berstandar ISO dan SMK swasta berstandar ISO (p = 0,001), antara SMK negeri berstandar ISO dan SMK negeri belum berstandar ISO (p = 0,000), serta antara SMK negeri berstandar ISO dan …

Pengembangan Buku Kerja Materi Eksponen Bercirikan Rme Untuk Siswa Smk Teknik, Sri Widowati

Jurnal Pendidikan Sains

Tujuan penelitian pengembangan ini adalah menghasilkan buku kerja berbahasa Inggris materi eksponen yang bercirikan Realistic Mathematics Education (RME) untuk siswa Sekolah Menengah Kejuruan (SMK) teknik kelas X serta memenuhi kriteria valid, praktis dan efektif. Proses validasi ahli dilakukan untuk mengetahui tingkat kevalidan buku kerja yang dihasilkan. Proses uji coba dilakukan untuk mengetahui tingkat kepraktisan dan keefektifan dari buku kerja yang dihasilkan. Berdasarkan proses validasi, diperoleh hasil bahwa buku kerja yang dihasilkan memenuhi kategori valid. Sedangkan dari proses uji coba diperoleh bahwa keterlaksanaan pembelajaran dengan menggunakan buku kerja berada pada kriteria praktis. Selain itu, rata-rata siswa memberikan respon positif dan hasil …

Peer Mediated Instruction And Intervention (Pmii) Tipe Classwide Peer Tutoring (Cwpt) Dan Kemampuan Akademik Pada Pembelajaran Ipa Biologi Smk, Hamsiah Hamsiah

Jurnal Pendidikan Sains

Pembelajaran IPA di SMKN 1 Bontang masih didominasi dengan strategi belajar konvensional yaitu metode belajar dengan ceramah. Hal ini berdampak terhadap hasil belajar kognitif IPA biologi yang cenderung masih rendah karena siswa belum terlatih menjadi pebelajar yang mandiri, sehingga inovasi pembelajaran PMII tipe CWPT dapat digunakan sebagai terobosan untuk mengembangkan hasil belajar kognitif. Penelitian ini dilakukan untuk mengetahui penerapan strategi CWPT dan kemampuan akademik pada pembelajaran IPA Biologi SMK. Penelitian eksperimen semu dengan rancangan pretest-posttest Nonequivalent Control Group. Hasil penelitian, yaitu: (1) ada pengaruh CWPT terhadap hasil belajar kognitif, (2) ada pengaruh kemampuan akademik terhadap hasil belajar kognitif, dan (3) …

Degradasi Anaerob Sampah Organik Dengan Bioaktivator Effective Microorganism-5 (Em-5) Untuk Menghasilkan Biogas, Metri Dian Insani

Jurnal Pendidikan Sains

Tujuan penelitian ini adalah untuk: (1) menganalisis perbedaan penggunaan tongkol jagung, kelaras pisang, dan kulit pisang dengan penambahan kotoran sapi terhadap tekanan biogas, (2) menganalisis perbedaan penggunaan tongkol jagung, kelaras pisang, dan kulit pisang dengan penambahan kotoran sapi terhadap lama waktu nyala api biogas yang dihasilkan, dan (3) menganalisis perbedaan penggunaan tongkol jagung, kelaras pisang, dan kulit pisang dengan penambahan kotoran sapi terhadap rasio C/N akhir. Penelitian eksperimen didesain menggunakan rancangan acak lengkap (RAL), dengan tiga perlakuan masing-masing dalam 3 kali ulangan. Hasil penelitian membuktikan bahwa: (1) terdapat perbedaan tongkol jagung, kelaras pisang, dan kulit pisang dengan penambahan kotoran sapi …

Pengaruh Penggunaan Peta Konsep Dalam Pembelajaran Inkuiri Terbimbing Ditinjau Dari Kemampuan Bernalar Siswa Kelas Xi, Agung Wahyudi

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk: (1) mengetahui perbedaan hasil belajar fisika antara siswa yang belajar menggunakan pembelajaran inkuiri terbimbing melalui peta konsep (PITPK) dan siswa yang belajar menggunakan pembelajaran inkuiri terbimbing (PIT); (2) menguji interaksi antara model pembelajaran dan kemampuan bernalar terhadap hasil belajar fisika; (3) mengetahui efektivitas PITPK dibandingkan PIT pada siswa dengan kemampuan bernalar tinggi; dan (4) mengetahui efektivitas PITPK dibandingkan PIT pada siswa dengan kemampuan bernalar rendah. Penelitian ini menggunakan rancangan faktorial 2 × 2 dengan teknik pengambilan sampel simple random sampling. Instrumen penelitian meliputi instrumen perlakuan berupa silabus, RPP, dan lembar observasi keterlaksanaan pembelajaran, serta instrumen pengukuran …

Pengaruh Penerapan Model Pembelajaran Pemerolehan Konsep Dipadu Pembelajaran Kooperatif Stad Terhadap Prestasi Belajar, Keaktifan, Dan Respons Siswa Pada Pembelajaran Ikatan Kimia, Putri Ridha Ilahi

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk mengetahui perbedaan: (1) prestasi belajar siswa menggunakan model pembelajaran pemerolehan konsep dipadu pembelajaran kooperatif STAD dan prestasi belajar siswa menggunakan model pembelajaran pemerolehan konsep dalam pembelajaran konvensional; (2) keaktifan siswa menggunakan model pembelajaran pemerolehan konsep dipadu pembelajaran kooperatif STAD dan keaktifan siswa menggunakan model pembelajaran pemerolehan konsep dalam pembelajaran konvensional; (3) respon siswa terhadap pembelajaran pemerolehan konsep dipadu pembelajaran kooperatif STAD dan respon siswa terhadap pembelajaran pemerolehan konsep dalam pembelajaran konvensional. Penelitian ini menggunakan rancangan penelitian deskriptif dan rancangan eksperimen semu (quasy experiment design). Data prestasi belajar dikumpulkan menggunakan tes objektif dan koefisien reliabilitas dihitung dengan …

Pengaruh Pendekatan Genius Learning Berbasis Kerja Ilmiah Terhadap Prestasi Belajar Fisika Ditinjau Dari Pengetahuan Awal Siswa Smpn 13 Balikpapan Tahun 2012, Suliyono Suliyono

Jurnal Pendidikan Sains

Penguasaan konsep-konsep fisika siswa akan lebih optimal apabila pendidik menerapkan strategi pembelajaran yang mampu meningkatkan keaktifan dan motivasi belajar siswa dengan tetap berlandaskan pada pendekatan konstruktivis. Pendekatan Genius Learning Berbasis Kerja Ilmiah (GLBKI) diyakini mampu menjawab tuntutan perkembangan pendidikan serta mempermudah siswa dalam mempelajari konsep-konsep fisika. Penelitian ini bertujuan untuk menguji perbedaan prestasi belajar fisika antara siswa yang belajar menggunakan pendekatan Genius Learning Berbasis Kerja Ilmiah dan siswa yang belajar menggunakan pembelajaran konvensional. Penelitian ini menggunakan desain eksperimen dengan pemberian perlakuan berupa pendekatan GLBKI pada kelas eksperimen yang dipilih secara acak, sedangkan kelas kontrol diberikan pembelajaran konvensional. Data prestasi belajar …

Pengaruh Model Pembelajaran Arias Dan Arias Dipadu Peta Konsep Terhadap Kemampuan Berpikir Kritis, Kognitif, Dan Afektif, Ismail Ismail

Jurnal Pendidikan Sains

Model pembelajaran Assurance, Relevance, Interest, Assessment, dan Satisfaction (ARIAS) dipadu peta konsep dapat meningkatkan kemampuan berpikir kritis, kognitif, dan afektif. Penelitian bertujuan untuk menguji pengaruh model pembelajaran ARIAS, ARIAS dipadu peta konsep, dan peta konsep terhadap kemampuan berpikir kritis, kognitif, dan afektif. Data penelitian dikumpulkan melalui tes uraian dan lembar observasi. Hasil analisis data menunjukkan bahwa nilai rata-rata kemampuan berpikir kritis, kognitif dan afektif untuk kelompok model pembelajaran ARIAS dipadu Peta Konsep tergolong kategori sangat baik, kelas perlakuan pembelajaran ARIAS, dan kelas perlakuan Peta Konsep termasuk kategori baik.

Relevansi Soft Skill Yang Dibutuhkan Dunia Usaha/Industri Dengan Yang Dibelajarkan Di Sekolah Menengah Kejuruan, Didik Suryanto

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk mendeskripsikan relevansi soft skill yang dibutuhkan oleh dunia usaha dan industri dengan soft skill yang dibelajarkan di Sekolah Menengah Kejuruan (SMK) di Kabupaten Blitar. Instrumen penelitian yang digunakan berupa angket atau kuesioner. Data dianalisis menggunakan teknik analisis deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa terdapat sejumlah soft skill yang relevan antara kebutuhan dunia usaha/industri dan pembelajaran di SMK menurut persepsi guru dan siswa, yaitu: (a) kejujuran dan sikap perilaku yang baik, (b) rasa tanggung jawab, (c) disiplin waktu, (d) kemampuan bekerja secara aman, (e) ketangguhan atau kegigihan dalam bekerja, (f) kemampuan mengatasi stres, (g) kemandirian atau tidak …

Penggunaan Media Bangun Geometri Untuk Menanamkan Konsep Penjumlahan Pecahan, Nanik Ulfa

Jurnal Pendidikan Sains

Pemahaman konsep merupakan aspek penting dalam pembelajaran matematika. Untuk menanamkan pemahaman konsep pada siswa yang masih berada pada tahap berpikir konkret, diperlukan bantuan media pembelajaran yang akrab dengan siswa. Dalam penelitian ini, media yang digunakan adalah media bangun geometri bidang. Penggunaan media tersebut diharapkan mampu menciptakan suasana pembelajaran yang menyenangkan serta mendorong keterlibatan aktif siswa dalam proses pembelajaran. Pembelajaran dilaksanakan melalui tiga tahap, yaitu: (1) tahap awal untuk mengecek pengetahuan prasyarat siswa, (2) tahap inti, pada tahap ini siswa memanipulasi media bangun geometri sesuai dengan panduan dalam Lembar Kerja Siswa (LKS) yang disusun oleh peneliti, dan (3) tahap penutup, yaitu …

Pengembangan Media Pembelajaran Interaktif Untuk Membangun Pemahaman Konsep Garis Singgung Persekutuan Dua Lingkaran, Vivin Nur Afidah

Jurnal Pendidikan Sains

Media pembelajaran interaktif yang dikembangkan adalah media pembelajaran interaktif yang dirancang berdasarkan karakteristik pembelajaran dengan bantuan komputer/Computer Assisted Instruction (CAI) tipe tutorial. Dirancang berdasarkan teori beban kognitif yaitu meminimalkan pemrosesan beban kognitif extraneous, mengatur pemrosesan beban kognitif intrinsic, dan mengembangkan pemrosesan beban kognitif germane. Penelitian pengembangan mengikuti model pengembangan 4D yaitu define (pendefinisian), design (perancangan), develop (pengembangan), dan disseminate (penyebarluasan). Simpulannya adalah (1) hasil validasi oleh ahli dan praktisi menilai media pembelajaran interaktif yang dikembangkan valid, (2) hasil pengamatan aktivitas guru dan siswa menunjukkan media pembelajaran interaktif memenuhi kriteria kepraktisan, (3) hasil kuis menunjukkan sebagian besar siswa mencapai tingkat pemahaman …