Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biochemistry (13)
- Physical Sciences and Mathematics (11)
- Biomedical Engineering and Bioengineering (8)
- Engineering (8)
- Physics (6)
-
- Biomechanics and Biotransport (5)
- Chemistry (5)
- Molecular Biology (5)
- Microbiology (4)
- Biology (3)
- Cell and Developmental Biology (3)
- Mechanical Engineering (3)
- Medicine and Health Sciences (3)
- Cell Biology (2)
- Optics (2)
- Structural Biology (2)
- Virology (2)
- Analytical Chemistry (1)
- Atomic, Molecular and Optical Physics (1)
- Bioinformatics (1)
- Biomechanical Engineering (1)
- Cancer Biology (1)
- Computer Sciences (1)
- Nanoscience and Nanotechnology (1)
- Neuroscience and Neurobiology (1)
- Other Biochemistry, Biophysics, and Structural Biology (1)
- Other Chemistry (1)
- Keyword
-
- Biological sciences (10)
- Pure sciences (8)
- Crystallography (2)
- Ubiquitin (2)
- X-ray crystallography (2)
-
- ABC Transporter (1)
- ABC transporter (1)
- Adhesions (1)
- Amsh (1)
- Bacteria (1)
- Bilayer asymmetry (1)
- Biomechanics (1)
- Biophysical (1)
- Biophysics (1)
- Bistability (1)
- Capsid proteins (1)
- Cholesterol (1)
- Cholestrol (1)
- Cloning (1)
- Cooperativity (1)
- Coronavirus (1)
- Cryo-electron tomography (1)
- Crystal structure (1)
- Cu (1)
- Deisgylation (1)
- Deubiquitinating enzymes (1)
- Deubiquitination (1)
- Deuterium nmr (1)
- Dha (1)
- Dna methylation (1)
- Publication
- Publication Type
Articles 31 - 34 of 34
Full-Text Articles in Biophysics
Effects Of Dna Methylation Pattern On The Chromatin Structure, Isabel Cristina Jimenez Useche
Effects Of Dna Methylation Pattern On The Chromatin Structure, Isabel Cristina Jimenez Useche
Open Access Dissertations
DNA methylation plays an essential role in various biological processes such as stem cell differentiation, imprinting, X-chromosome inactivation, etc. Increased DNA methylation levels have been associated with chromatin compaction leading to gene silencing. For example, abnormal DNA methylation is associated with silencing of tumor suppressor genes and is observed in the onset of tumorigenesis. There is evidence suggesting that not all methylation events are relevant in chromatin compaction and the initiation of cancer. It seems that methylation at certain locations of the DNA might be key to start chromatin compaction and gene silencing, but the location of this methylation sites …
Structural And Functional Characterization Of The Endosome-Associated Deubiquitinating Enzyme Amsh, Christopher Williamson Davies
Structural And Functional Characterization Of The Endosome-Associated Deubiquitinating Enzyme Amsh, Christopher Williamson Davies
Open Access Dissertations
The endosomal sorting complexes required for transport (ESCRT) machinery is a ubiquitin-dependent molecular mechanism made of up of four individual complexes: ESCRT-0, -I, -II, III, that is necessary for regulating the degradation of cell surface receptors directed towards the lysosome. Not only are the ESCRTs implicated in endosomal sorting and trafficking of proteins, its members also have roles in other important biological processes such as: cytokinesis, HIV budding, transcriptional regulation, and autophagy. As a function of its involvement in several processes throughout the cell, the ESCRT machinery is implicated in a wide variety of diseases including cancer, neurological disease, bacterial …
Measuring And Modeling The Response Characteristics Of The Environmental Phosphate Transducer In Escherichia Coli, Chetan Sood
Measuring And Modeling The Response Characteristics Of The Environmental Phosphate Transducer In Escherichia Coli, Chetan Sood
Open Access Dissertations
The PhoR/PhoB two-component system in Escherichia coli is a biological transducer that senses the limitation of environmental inorganic orthophosphate, the bacteria's preferred source of the essential nutrient phosphate, and transmits that information to the interior of the cell initiating a response that mitigates phosphate starvation. In the first part of this study, we present and apply a fluorescence microscopy technique to measure, in vivo, the dynamic response characteristics of the transducer with single-cell resolution. We report that the transience in the PhoR/PhoB TCS response is consistent with the transducer having a threshold sensitivity to the concentration of environmental phosphate, …
Interaction Between Maltose Binding Protein And Escherichia Coli Maltose Transporter, Yan Huang
Interaction Between Maltose Binding Protein And Escherichia Coli Maltose Transporter, Yan Huang
Open Access Theses
The ATP-binding cassette (ABC) transporter superfamily is one of the largest families of transport proteins. The ABC transporters are responsible for selective permeability of solute across membranes energized by ATP hydrolysis, which occurs in all domains of life. Maltose transporter is an ABC importer that mediates maltose/maltodextrin uptake in bacteria and archaea. It is identified as an essential virulence factor in pathogenic species of Streptococcis pyogenes and Vibrio cholera (1, 2). Escherichia coli maltose transporter is a well-characterized system with crystal structures and exclusive biochemical studies available. Knowledge of the E. coli maltose transport mechanism will lead to a better …