Life Sciences Commons^™

Mercury Contamination In Selected Edible Plants And Soil From Artisanal And Small-Scale Gold Mining In Sukabumi Regency, Indonesia, Grace Serepina Saragih, Ely Rahmi Tapriziah, Yunesfi Syofyan, Siti Masitoh, Yohana Sari Hotmatua Pandiangan, Andriantoro Andriantoro

Makara Journal of Science

Artisanal and small-scale gold mining (ASGM) activities often pollute soil, water, and air, thereby achieving widespread proliferation, and contaminating the surrounding biota including plants. Mercury contamination on agricultural land around ASGM areas has been widely reported. This study aims to determine the total mercury contamination in plants and soil around active ASGM sites in Sukabumi Regency, Indonesia, namely, Waluran, Lengkong, and Ciemas Districts. Total mercury (Hg) content was measured from 27 plant samples (including cassava [Manihot utilisima], rice [Oryza sativa], and papaya [Carica papaya]), 7 rhizosphere soil samples, and 7 non-rhizosphere soil samples. Data …

Bioaccumulation Of Trace Metals For Daily Fish Consumption From Selected Former Tin Mining Ponds In Peninsular Malaysia: A Review On Safety Of Fish Consumption, Mohd Hafiz Rosli, Amirul Azuan Md Joni, Nur Khaliesah Abdul Malik

Makara Journal of Science

Tin mining was the predominate mining industry in Malaysia, especially during the mid-19th century. Most of the former mining areas have been reused for aquaculture purposes. Fish produced from former mining areas have been misunderstood as a high health risk if consumed due to their likelihood of containing high heavy metal content in their tissue. Therefore, we review national information on trace metals levels in the tissue of fish from selected former mining ponds in Peninsular Malaysia, together with background concentration of trace metals in their surroundings and food security and human health implications. Seven trace metals (Cu, Zn, As, …

Antimicrobial Activity Of Ferulic Acid In Indonesian Purple Rice Through Toll-Like Receptor Signaling, Ernanin Dyah Wijayanti, Anna Safitri, Dian Siswanto, Lidwina Faraline Triprisila, Fatchiyah Fatchiyah

Makara Journal of Science

Purple rice is a potential source of ferulic acid, which has antimicrobial properties. However, the inhibitory mechanism of ferulic acid on the growth of bacteria, particularly Salmonella and Listeria, has not been elucidated. This study aimed to determine the bioactivity of ferulic acid from purple rice as an antimicrobial agent against Salmonella typhimurium and Listeria monocytogenes using in vitro and in silico analyses. The antimicrobial activity of a purple rice ferulic acid extract was tested using the agar well diffusion method. Its effect on bacterial cells was observed using scanning electron microscopy. Ferulic acid was confirmed to have antimicrobial …

Magnetically Separable Fe3o4/Sio2/Tio2 Photocatalyst Composites Prepared Through Hetero Agglomeration For The Photocatalytic Degradation Of Paraquat, Jarnuzi Gunlazuardi, Adel Fisli, Ridwan Ridwan, Yuni Krisyuningsih Krisnandi, Didier Robert

Makara Journal of Science

A photocatalyst supported on magnetic material allows the simple technique by using an external magnetic material to separate photocatalyst from the treated water. Thus, it is a magnetically separable nanoparticles photocatalyst (MSNP). The use of superparamagnetic nanoparticles that do not pose spontaneous magnetic moment thus could be dispersed in water and can be recollected easily by an external magnetic bar. We prepare Fe₃O₄/SiO₂/TiO₂ composite by hetero agglomeration of Fe₃O₄/SiO₂ and TiO₂ at a pH range of 3 to 6.2 in an aqueous slurry_.The Fe_{3 …}

A Systematic Review And Meta-Analysis Of Most Endoparasites And Ectoparasites During Past Decade In Iraq, Karwan S. Najm Al-Marjan, Hawri H. Mohammed Jabbary, Liza J. Yousif, Fouad H. Kamil, Najat J. Ahmed, Suzan S. Ali, Layla A. Kareem, Ahmed A. Ab.Jabar, Awat M. Mustafa, Kalthum Kh. Ahmed

Polytechnic Journal

Today, our society is polluted with the diseases belong to various types including inherited, germs, hazard infectious with physiologic one. Information on the disease epidemiology and reviewing data analysis helps us in controlling strategies. Since the early 1980s, this region has faced wars, political irregularity, and economic collapse, leads to the migration of over ten million people, two million have internally displaced. In addition to several other factors which mentioned by ministry of health includes poor sanitation, poor nutrition and also population density because population of Iraq has more than doubled in the last 25 years. The aim of any …

Seroprevalence Of Toxoplasma Gondii Immunoglobulin G And Immunoglobulin M Antibodies Among Leukemia Patients In Erbil City-Kurdistan Region/Iraq By Enzyme-Linked Immunosorbent Assay Technique, Hemdad H. Mawlood

Polytechnic Journal

The current study was revealed the seroprevalence of Toxoplasma gondii immunoglobulin (Ig)G and IgM among different types of leukemia (Acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin lymphoma [HL], multiple myeloma [MM], non-HL [NHL], and chronic myeloid leukemia) from male and female patients in different age groups (18–≥48 years) using indirect enzyme-linked immunosorbent assay. The results of 140 cases of different types of leukemia showed the highest T. gondii IgG (44.44%) among MM leukemia whereas T. gondii IgM highest (12.5%) among NHL leukemia. Significant (P ≤ 0.01) differences between T. gondii antibodies and age group were recorded, that increased with the …

The Allelopathic Potential Of Foliar Application Of Aqueous Extracts Of Chickpea On Growth And Yield Of Chickpea, Kawa A. Ali, Kawa K. Miran

Polytechnic Journal

A pot experiment was executed in the college of science, Salahaddin university glass house to investigate the allelopathic potentiality of aqueous chickpea Cicer arietinum L. seed extracts that was foliar sprayed on chickpea plants 45 days after sowing to estimate growth, yield, yield components, and seeds chemical characteristics. Results showed that the allelopathic effect was significant on chickpea plant height, number of pods per plant, seeds per pod, shoot dry weight, seed yield per plant, biological yield per plant, harvest index, hundred seeds weight, nitrogen, protein, and phosphorus content. The allelopathic effect was on its own species, and the effect …

Assessment Of Child Physical Abuse Among Mothers In Mala A Fandi Health Care Centre/Erbil City, Hanaa O. Saadi, Yasin K. Amin, Abass A. Ahmed

Polytechnic Journal

Child physical abuse is an important cause of pediatric morbidity and mortality and is associated with major physical and mental health problems that can extend into adulthood. The main research purpose was to assess sociodemographic characteristics of mothers and find out the most common types and physical abuse among children. This descriptive study is conducted on Mothers of Abused Child at Mala A fandi Health Care Centre in Erbil city of Kurdistan region of Iraq. A convenient sampling was used to choose 100 Mothers who visited particular health center. Questionnaire was used as a tool for collecting data from Mothers …

Influence Of Mixture Proportions On Fresh And Mechanical Properties Of Self-Consolidating Concrete, Ghafur H. Ahmed

Polytechnic Journal

Self-consolidating concrete (SCC) is a concrete that able to flow and consolidate under its own weight, and it is cohesive enough to fill spaces of almost any size and shape without segregation or bleeding. In this study, workability and strength characteristics of seven SCC mixes were examined and compared with two additional vibrated mixes of normal and high strength. For this purpose, the flowability, deformability, and passing ability of fresh concrete mixes were tested through slump test, slump flow, T500, and the J-ring tests. Furthermore, the hardened concrete specimens were tested for mechanical properties with the variation in shape and …

Molecular Phylodiagnosis Of Taenia Hydatigena From Stray Dogs In Erbil Province-Kurdistan Region/Iraq, Zuber I. Hassan

Polytechnic Journal

Taenia hydatigena is one of the most prevalent taeniid species of livestock and dogs. A total of 52 fecal samples were collected from September 2019 to May 2020. The highest prevalence rate was observed in Rural area (21.15%, 11/52), as compared to Urban area (15.38%, 8/52). Nineteen (9 males and 10 females) out of 52 dogs were infected with T. hydatigena; there were no significant differences in prevalence based on molecular technique was observed between females (19.23%) and males (17.31%). The DNA’s of taeniid eggs were extracted, amplified, and sequenced by targeting of mitochondrial cytochrome c oxidase subunit 1 (cox1). …

Survey Of Public Knowledge And Implementation Regarding Covid-19 In Sulaymaniyah City, Ismail Y. Maolood, Abdulrahman A. Mhmood

Polytechnic Journal

The currently pandemic virus called SARS-CoV-2 is an international health issue that we have interacted with since World War II. The virus was discovered in the Chinese city of Wuhan in 2019 and has since spread worldwide. Globally, the number of cases is increasing, with new cases being reported in Asia, Africa, the Americas, and Europe. This paper is intended to analyze 2019 novel coronavirus (COVID-19) knowledge, perceptions, and behaviors toward the substance within the general population in the city of Sulaymaniyah. The study was conducted as a cross-sectional survey with 100 adults from various locations throughout Sulaymaniyah. These places …

Challenges In The Implementation Of The Bologna Process, Jabbar H. Ade

Polytechnic Journal

Bologna process is the instruction for reshaping in the higher education system, which created significant obstacles for its implementation. The objective of this study is to investigate the issues and challenges faced Kurdistan universities during the implementation of the Bologna process. In this study, three universities have been focused; two public and a private university. A questionnaire form was designed or the three universities’ staff (Erbil Polytechnic University [EPU], Soran University, and Cihan University) which included several questions about the challenges faced them during European Credit Transfer System (ECTS) implementation. The results show that Cihan University provides more knowledge about …

Occurrence Of Blatem Among Pseudomonas Aeruginosa Strains Isolated From Different Clinical Samples In Erbil City, Sevan H. Bakir, Fattma A. Ali, Bashdar M. Hussen, Shahin H. Mustafa, Ahmed Akil, Shilan S. Ahmad

Polytechnic Journal

Pseudomonas aeruginosa was a significant source of nosocomial infection with the presence of extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBL) genes in P. aeruginosa being progressively documented globally. The purpose of this investigation was to detection the occurrence of MBL and ESBL in P. aeruginosa isolates acquired from diverse clinical samples, as well as the prevalence of blaTEM genes producing ESBLs. A total of 227 samples were obtained from various clinical specimens (wound, urine, sputum, bronchial wash, and burn) at public hospitals in Erbil region. Microorganism was obtained, treated, and recognized using normal microbiological culture procedures, biochemical testing, DNA extraction, and …

Molecular Characterization Of Proteus Spp. From Patients Admitted To Hospitals In Erbil City, Treska Dh. Kamil, Sanaria F. Jarjes

Polytechnic Journal

The study was carried out to detect the identity of Proteus spp. isolated from various clinical specimens in Erbil City by polymerase chain reaction (PCR) technique. Specimens were of urine, wounds swabs, burn swabs, vaginal swabs, ear swabs, eye swabs, and sputum. Fifty-one Proteus isolates, (47) Proteus mirabilis, and (4) Proteus vulgaris, were undergone PCR assay using specific primers, targeting the genes ureR and Urease C (ureC), that encode for urease enzyme as a virulence factor of Proteus species. It was found that all isolates of Proteus mirabilis yielded positive result for ureR gene with an amplicon length of 225 …

The Dissolution Enhancement Of Meloxicam Tablets From The Synergistic Effect Of Hydrotropic And Sublimating Agent, Hemn L. Qader, Tara A. Abdula, Huner K. Omer

Polytechnic Journal

Background and Objective: Drugs which fall into Class II of Biopharmaceutical Classification System suffer from poor aqueous solubility that limits the dissolution and oral bioavailability. The improvement of the dissolution rate of this class of drug is an important issue for enhancing their bioavailability and therapeutic efficacy. The objective of this study is to investigate the magnitude of enhancement of the dissolution rate of Class II drug “Meloxicam (MLX)” by using more than one solubility enhancement technique. Methods: MLX-sodium benzoate solid dispersion at different ratios were prepared by kneading method to enhance the solubility, then MLX tablets were prepared by …

Hypoglycemic And Hypolipidemic Potential Of Ginger-Thyme Combined Extract In Sucrose-Induced Hyperglycemic Rates, Burhan A. Salih, Dilzar S. Asaad

Polytechnic Journal

The current study is designed to investigate the in vivo action of ginger- thyme combined crude extract on hyperglycemia and obesity related measurements in sucrose induced chronic hyperglycemia experimental model in albino male rats. Twenty-five male albino rats were divided into five groups (N=5 for each); First group was regarded as control which consists of rats feed with normal diet and water ad libitum, while second group was the model which consists of rats fed with high sucrose fed (HSF) (50%sucrose). and other three groups were rats which treated with three different doses of ginger-thyme combination extract (125mg/kg, 250 mg/kg …

Growth Of (Platanus Orientalis L.) Seedlings Under Different Drought Stress Condition, Halmat A. Sabr

Polytechnic Journal

A lath house study was performed in order that understand the adjustment responses to three different water conditions of Platanus orientalis L. seedlings trying to make them able to adjust to new under dry conditions. Eight months seedlings were exposed to three water regimes (90, 60 and 30% water holding capacity [WHC]) were used r with a completely randomize design. The following parameters were measured; seedling height, leaf area, total chlorophyll content in the leaves, root length, root to shoot ratio, total dry mass, and leaf area ratio. It is found that water stress significantly reduced height and base diameter …

Identification Of Relationships Between Fingerprint Patterns And Gender In Koya, Kurdistan Region, Iraq., Zaitoon A. Hamad, Hemn R. Salih, Layla K. Ali

Polytechnic Journal

According to this research probe the correlation between fingerprints and the gender for all 10 fingerprints. For this inquiry, 4939 samples were collected from 247 females and 247 male’s ages between 7 and 13 years old. This is the first systematic research of its kind to check at ten fingerprints for people from Koya, Kurdistan region north of Iraq. As per the findings, gender identity is accurate for people with any of their ten fingerprints. After magnifying the obviously acquired photos, the four basic fingerprint structures were identified and registered: Arch, Radial loop, Ulner loop, and Whorl. Statistical analysis was …

Computational Fluid Dynamic Optimization Of Supply And Return Duct Position For Zone Air Distribution, Bashir E. Kareem, Younis K. Khdir

Polytechnic Journal

Air conditioning accounts for roughly half of all energy consumption in residential buildings. Today’s issue is optimizing the air conditioning system and methods of conveying heated and cooled air to prevent additional energy consumption. The optimal supply and return duct position is studied and the results based on the minimum air temperature and pressure in the room, while the room air distribution is taken into account. The main objective of air conditioning, which is impacted by duct position, is to provide thermal comfort in the room. Using Computational Fluid Dynamic, a controlled zone is designed and analyzed in the room …

Hubungan Antara Riwayat Kunjungan Antenatal Care (Anc) Dengan Kejadian Lahir Mati Di Indonesia, Lila Kesuma Hairani, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

Pada tahun 2015, sebanyak 65% dari total kelahiran mati diseluruh dunia disumbang oleh sepuluh negara dengan jumlah kelahiran mati terbanyak. Indonesia menempati posisi ke-8 dengan total sebanyak 73.400 kejadian dengan angka lahir mati (stillbirth rate/SBR) sebesar 13 per 1.000 kelahiran. Rendahnya cakupan layanan antenatal diduga berhubungan secara kuatdengan rendahnya lahir mati antepartum. Studi ini dilakukan dengan tujuan untuk melihat hubungan riwayat kunjungan antenatal (antenatal care/ANC) dengan kejadian lahir mati diIndonesia menggunakan data sekunder yang bersumber dari IFLS 5 tahun 2014. Desain penelitian ini berupa studi potonglintang dengan total sampel yang digunakan adalah sebesar 6.314 kelahiran. Analisis data dilakukan hingga tingkat …

Gambaran Epidemiologi Hepatitis A Berdasarkan Data Kejadian Luar Biasa Dan Data Kasus Di Kabupaten Bogor Tahun 2019, Nurjannah Nurjannah, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

Kejadian luar biasa (KLB) Hepatitis A Kabupaten Bogor terus meningkat setiap tahunnya. Pada tahun 2018 terdapat 29 kasusdan pada tahun 2019 meningkat hingga 495 kasus. Penelitian ini bertujuan untuk menggambarkan epidemiologi berdasarkan orang, tempat, waktu. Hasil penelitian ini diharapkan dapat digunakan sebagai dasar upaya intevensi yang lebih optimaldan tepat sasaran. Data penelitian diambil dari laporan KLB dandari data kasus Hepatitis A di Dinas Kesehatan Kabupaten Bogor dari Januari-Desember 2019 dan didokumentasikan ke dalam tabel observasi, pengambilan data dilakukan pada Bulan Februari2020 dengan desain penelitian case series. Hasil penelitian ini menunjukkan dari 495 kasus yang mengalami gejala klinis,11,3% terkonfimasi positif, sebagian …

Hubungan Faktor Pejamu Dan Lingkungan Dengan Pneumonia Balita Di 5 Provinsi Di Pulau Sulawesi, Alfi Lailiyah, Nuning Maria Kiptiyah

Jurnal Epidemiologi Kesehatan Indonesia

Pneumonia merupakan penyakit menular yang menginfeksi paru-paru. Period prevalence pneumonia balita di 5 provinsi di Sulawesi lebih tinggi dibanding angka nasional. Penelitian ini bertujuan untuk mendapatkan gambaran dan faktor-faktor yang berhubungan dengan pneumonia balita di 5 Provinsi di Pulau Sulawesi. Data penelitian ini bersumber dari Survei Demografi dan Kesehatan Indonesia (SDKI) 2012. Desain dalam penelitian ini adalah cross-sectional dengan uji chi-square dan hasil ukur prevalence ratio (PR). Variabel pada penelitian ini adalah faktor pejamu (umur balita, jenis kelamin, berat badan lahir, pemberian vitamin A, status imunisasi campak dan DPT) dan faktor lingkungan (pendidikan ibu, tempat tinggal, bahan bakar memasak, keberadaan …

Hubungan Status Gizi Dengan Prestasi Belajar Siswa Kelas 1-3 Sekolah Dasar, Muhammad Hidayat Sahid, Asri Adisasmita Prof, Ratna Djuwita

Jurnal Epidemiologi Kesehatan Indonesia

Status gizi merupakan ukuran keberhasilan dalam pemenuhan nutrisi anak yang diukur berdasarkan berat badan dan tinggi badan anak. Data status gizi pada anak usia umur 5-12 tahun di DKI Jakarta menunjukkan underweight 14,0%, stunting 22,7%, wasting 9,9%, dan overweight 6,8%. Data secara spesifik untuk wilayah Jakarta Selatan adalah underweight 7,4%, stunting 17,8%, wasting 6,3%, dan overweight 7,3%. Dari data tersebut didapatkan gambaran mengenai permasalahan gizi yang terjadi di DKI Jakarta. Permasalahan gizi memiliki dampak pada tumbuh kembang anak. Gizi merupakan salah satu faktor penting yang berpengaruh terhadap prestasi akademik siswa. Tujuan dari penelitian ini adalah untuk mengetahui hubungan status gizi …

Agropastoral Systems An Alternative To Revert Pasture Degradation In The Cerrados Of Brazil: Preliminary Results, Manuel C. M. Macedo, J. A. M. Bono, A. H. Zimmer, F. P. Costa, Tsutomu Kanno, Cesar Heraclides Behling Miranda, A. N. Kichel

IGC Proceedings (1977-2023)

A long term experiment was set to test the hypothesis that agropastoral systems could improve crop and animal production, being more profitable and sustainable relative to economical, biological and environmental aspects, than continuous and traditional crop and grazing pasture systems. Five farming systems are being tested: two traditional (continuous soybean annual cropping and continuous pasture cropping) and three agropastoral systems (two combinations of four by four years of rotational crop-pasture systems and one by three years of crop-pasture rotation). Animal production in continuous pasture cropping measured as liveweight gain/ha (LWG) are declining along the years in the sub-treatment without fertilizer …

Evaluation Of A Number Of Grass Species For Restoring Degraded Semi-Arid Rangelands In Southern Africa, K. Kellner, S. De Wet

IGC Proceedings (1977-2023)

The biophysical environment is an important determinant of land degradation in both commercial and communal land tenure systems in South Africa. According to a recent study on the status of land degradation, approximately 25% of the total land cover in South Africa is degraded. Several technologies exist to restore the soil and vegetation degraded areas in natural pastures. To improve the production and biodiversity potential for agricultural and conservation uses in these rangelands, a common restoration technology includes the cultivation the eroded and compacted soil surfaces by rip- ploughing and the re-vegetation with high productive, palatable and perennial species. Five …

A Snapshot Investigation Into The Availability And Access To Codeine-Containing Medications Amongst The Irish Population., Katie O'Brien, Pádraig Mckeown, Joseph Phelan

International Undergraduate Journal of Health Sciences

Codeine phosphate is a mild to moderate analgesic and has a weak cough suppressant activity that is available to purchase as an over the counter (OTC) painkiller in Ireland as a compound product. In recent years, countries such as Australia have introduced laws that prohibit the sale of the drug without a valid prescription. This move by Australia begs the question as to why this legislation was introduced and should Ireland follow suit.

The primary aims of the study were to determine knowledge among the general public of codeine-containing medications and their usage levels. The survey also investigated whether current …

An Investigation Into The Prevalence Of Vancomycin-Resistant Enterococci Within An Irish Hospital, Dylan Casey

International Undergraduate Journal of Health Sciences

Vancomycin-resistant enterococci (VRE) are well-recognised nosocomial pathogens that pose a significant threat to public health. Associated with poorer clinical outcomes than their vancomycin-sensitive counterparts, the prevalence of VRE in Ireland has increased in recent times, with the European Antimicrobial Resistance Surveillance Network reporting that out of 29 countries, Ireland demonstrated the highest rates of vancomycin resistance among invasive Enterococcus faecium isolates between 2011 and 2014 (2011; 34.9%, 2012; 44.0%, 2013; 42.7%, 2014; 45.1%). Herein, we investigate VRE prevalence in the Mercy University Hospital (MUH) – an acute care hospital in southern Ireland. A total of 21 first-time VRE infections were …

Implications Of Salinity Normalization Of Seawater Total Alkalinity In Coral Reef Metabolism Studies, Travis A. Courtney, Tyler Cyronak, Alyssa J. Griffin, Andreas J. Andersson

Marine & Environmental Sciences Faculty Articles

Salinity normalization of total alkalinity (TA) and dissolved inorganic carbon (DIC) data is commonly used to account for conservative mixing processes when inferring net metabolic modification of seawater by coral reefs. Salinity (S), TA, and DIC can be accurately and precisely measured, but salinity normalization of TA (nTA) and DIC (nDIC) can generate considerable and unrecognized uncertainties in coral reef metabolic rate estimates. While salinity normalization errors apply to nTA, nDIC, and other ions of interest in coral reefs, here, we focus on nTA due to its application as a proxy for net coral reef calcification and the importance for …

Inhibition Of Bruton Tyrosine Kinase Reduces Neuroimmune Cascade And Promotes Recovery After Spinal Cord Injury, Chen Guang Yu, Vimala Bondada, Hina Iqbal, Kate L. Moore, John C. Gensel, Subbarao Bondada, James W. Geddes

Physiology Faculty Publications

Microglia/astrocyte and B cell neuroimmune responses are major contributors to the neurological deficits after traumatic spinal cord injury (SCI). Bruton tyrosine kinase (BTK) activation mechanistically links these neuroimmune mechanisms. Our objective is to use Ibrutinib, an FDA-approved BTK inhibitor, to inhibit the neuroimmune cascade thereby improving locomotor recovery after SCI. Rat models of contusive SCI, Western blot, immunofluorescence staining imaging, flow cytometry analysis, histological staining, and behavioral assessment were used to evaluate BTK activity, neuroimmune cascades, and functional outcomes. Both BTK expression and phosphorylation were increased at the lesion site at 2, 7, 14, and 28 days after SCI. Ibrutinib …

The Utilization Of Enzymes And Enzyme Products For Antimicrobial Effects, Brandon Edward Burdette

Theses and Dissertations

Bacterial resistance is outpacing the discovery of novel antimicrobials. Therefore, it is essential to look at antimicrobials using novel methods. MTAN is a crucial enzyme for some bacteria such as Helicobacter pylori. Transition state analog inhibitor design and fragment-based drug design are drug design approaches typically used independently, but combining these techniques yields inhibitors that bind tightly and are effective in pM concentrations. We demonstrate the efficacy of the combined techniques by investigating the inhibition of HpMTAN, which is an essential enzyme. Enzyme byproducts can also be effective for causing bacterial cell death, hydrolyzing GsdmD by caspases-1/4/5/11 results in an …