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2020

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Articles 451 - 480 of 13409

Full-Text Articles in Life Sciences

Smokejumper Obituary: Beals, David Ellis (Mccall 1945), National Smokejumper Association Dec 2020

Smokejumper Obituary: Beals, David Ellis (Mccall 1945), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.


Pathway‐Extended Gene Expression Signatures Integrate Novel Biomarkers That Improve Predictions Of Patient Responses To Kinase Inhibitors, Ashis Bagchee‐Clark, Eliseos J. Mucaki, Tyson Whitehead, Peter Rogan Dec 2020

Pathway‐Extended Gene Expression Signatures Integrate Novel Biomarkers That Improve Predictions Of Patient Responses To Kinase Inhibitors, Ashis Bagchee‐Clark, Eliseos J. Mucaki, Tyson Whitehead, Peter Rogan

Biochemistry Publications

Cancer chemotherapy responses have been related to multiple pharmacogenetic biomarkers, often for the same drug. This study utilizes machine learning to derive multi‐gene expression signatures that predict individual patient responses to specific tyrosine kinase inhibitors, including erlotinib, gefitinib, sorafenib, sunitinib, lapatinib and imatinib. Support vector machine (SVM) learning was used to train mathematical models that distinguished sensitivity from resistance to these drugs using a novel systems biology‐based approach. This began with expression of genes previously implicated in specific drug responses, then expanded to evaluate genes whose products were related through biochemical pathways and interactions. Optimal pathway‐extended SVMs predicted responses in …


Nitrogen Uptake By Two Plants In Response To Plant Competition As Regulated By Neighbor Density, Xuan Jia, Chaohe Huangfu, Dafeng Hui Dec 2020

Nitrogen Uptake By Two Plants In Response To Plant Competition As Regulated By Neighbor Density, Xuan Jia, Chaohe Huangfu, Dafeng Hui

Biology Faculty Research

Plant species may acquire different forms of nitrogen (N) to reduce competition for the same resource, but how plants respond to neighbors with different densities in their N uptake is still poorly understood. We investigated the effects of competition regime on the uptake of different N forms by two hygrophytes, Carex thunbergii and Polygonum criopolitanum, by conducting a hydroponic test of excised roots and an in situ experiment in a subtropical wetland ecosystem. The two species were grown either in monocultures or mixtures with various neighbor densities. Root functional traits and N uptake rates of different N forms were measured. …


Effects Of Wollastonia Biflora Expansion On The Soil Seed Bank In Native Forest Communities On A Tropical Coral Island, Yao Huang, Hai Ren, Jun Wang, Nan Liu, Shuguang Jian, Hongyue Cai, Dafeng Hui, Qinfeng Guo Dec 2020

Effects Of Wollastonia Biflora Expansion On The Soil Seed Bank In Native Forest Communities On A Tropical Coral Island, Yao Huang, Hai Ren, Jun Wang, Nan Liu, Shuguang Jian, Hongyue Cai, Dafeng Hui, Qinfeng Guo

Biology Faculty Research

Invasive plants and native weeds (i.e., undesirable plant species) often have negative effects on native ecosystems. However, the effects of weed expansion on soil seed banks and seedling emergence in native forests have not been well investigated. In this study, we used a seedling emergence assay to assess the effects of expansion by a native weed, the perennial C4 herb Wollastonia biflora, on the soil seed bank and above-ground vegetation in forests on Yongxing Island, a coral island in the South China Sea. We found that W. biflora expansion was associated with a reduced abundance of native species in the …


Disadvantaged Vs. Non-Disadvantaged Drinking Water: San Joaquin County Groundwater Variable By Contaminant, Megan Brooks Dec 2020

Disadvantaged Vs. Non-Disadvantaged Drinking Water: San Joaquin County Groundwater Variable By Contaminant, Megan Brooks

Master's Projects and Capstones

This research explored drinking water wells that have detectable levels of arsenic and nitrate in disadvantaged vs. non-disadvantaged communities in San Joaquin County. The CalEnviroScreen 3.0 program and Groundwater Ambient Monitoring Program (GAMA) are used to measure disadvantaged communities and water quality data respectively. The CalEnviroScreen 3.0 scoring formula is used to calculate which census tracts are disadvantaged based on indices that measure pollution burden and population characteristics. The scoring is then combined with a census tract layer using Geographic Information Systems (GIS) technology. The disadvantaged community data are overlaid with GAMA groundwater well data to locate which communities are …


Livestock Indemnity Program: A Case For Managing Risk With Good Recordkeeping, Jay Parsons Dec 2020

Livestock Indemnity Program: A Case For Managing Risk With Good Recordkeeping, Jay Parsons

Cornhusker Economics

Keeping good records is an important risk management tool for agricultural producers. Good records provide accurate, complete and consistent information that leads to better decision making. Good records also keep the farm or ranch operation in a good position to participate in USDA programs when those opportunities are available.

The Livestock Indemnity Program (LIP), one of the USDA disaster assistance programs administered by the Farm Service Agency (FSA), is an example of how good recordkeeping can be rewarded. LIP provides compensation to eligible livestock producers who have suffered livestock death losses in excess of normal mortality due to adverse weather, …


Nss, The Silencing Suppressor Of Tomato Spotted Wilt Orthotospovirus, Interferes With Ja-Regulated Host Terpenoids Expression To Attract Frankliniella Occidentalis, Jiao Du, Xiaoyu Song, Xiaobin Shi, Xin Tang, Jianbin Chen, Zhanhong Zhang, Gong Chen, Zhuo Zhang, Xuguo Zhou, Yong Liu, Deyong Zhang Dec 2020

Nss, The Silencing Suppressor Of Tomato Spotted Wilt Orthotospovirus, Interferes With Ja-Regulated Host Terpenoids Expression To Attract Frankliniella Occidentalis, Jiao Du, Xiaoyu Song, Xiaobin Shi, Xin Tang, Jianbin Chen, Zhanhong Zhang, Gong Chen, Zhuo Zhang, Xuguo Zhou, Yong Liu, Deyong Zhang

Entomology Faculty Publications

Tomato spotted wilt orthotospovirus (TSWV) causes serious crop losses worldwide and is transmitted by Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae). NSs protein is the silencing suppressor of TSWV and plays an important role in virus infection, cycling, and transmission process. In this research, we investigated the influences of NSs protein on the interaction of TSWV, plants, and F. occidentalis with the transgenic Arabidopsis thaliana. Compared with the wild-type Col-0 plant, F. occidentalis showed an increased number and induced feeding behavior on transgenic Arabidopsis thaliana expressing exogenous NSs. Further analysis showed that NSs reduced the expression of terpenoids synthesis-related genes and …


Karyotype Evolution In 10 Pinniped Species: Variability Of Heterochromatin Versus High Conservatism Of Euchromatin As Revealed By Comparative Molecular Cytogenetics, Violetta R. Beklemisheva, Polina L. Perelman, Natalya A. Lemskaya, Anastasiya A. Proskuryakova, Natalya A. Serdyukova, Vladimir N. Burkanov, Maksim B. Gorshunov, Oliver A. Ryder, Mary Thompson, Gina Lento, Stephen James O'Brien, Alexander S. Graphodatsky Dec 2020

Karyotype Evolution In 10 Pinniped Species: Variability Of Heterochromatin Versus High Conservatism Of Euchromatin As Revealed By Comparative Molecular Cytogenetics, Violetta R. Beklemisheva, Polina L. Perelman, Natalya A. Lemskaya, Anastasiya A. Proskuryakova, Natalya A. Serdyukova, Vladimir N. Burkanov, Maksim B. Gorshunov, Oliver A. Ryder, Mary Thompson, Gina Lento, Stephen James O'Brien, Alexander S. Graphodatsky

Biology Faculty Articles

Pinnipedia karyotype evolution was studied here using human, domestic dog, and stone marten whole-chromosome painting probes to obtain comparative chromosome maps among species of Odobenidae (Odobenus rosmarus), Phocidae (Phoca vitulina, Phoca largha, Phoca hispida, Pusa sibirica, Erignathus barbatus), and Otariidae (Eumetopias jubatus, Callorhinus ursinus, Phocarctos hookeri, and Arctocephalus forsteri). Structural and functional chromosomal features were assessed with telomere repeat and ribosomal-DNA probes and by CBG (C-bands revealed by barium hydroxide treatment followed by Giemsa staining) and CDAG (Chromomycin A3-DAPI after G-banding) methods. We demonstrated diversity of heterochromatin among pinniped karyotypes in terms of localization, …


Consistently Biased: Documented Consistency In Self-Reported Holiday Healthfulness Behaviors And Associated Social Desirability Bias, Courtney Bir, Nicole Olynk Widmar Dec 2020

Consistently Biased: Documented Consistency In Self-Reported Holiday Healthfulness Behaviors And Associated Social Desirability Bias, Courtney Bir, Nicole Olynk Widmar

Department of Agricultural Economics Faculty Publications

Holiday healthfulness conversations are dominated by overindulgence of consumption and then, largely in reference to resolutions to do better, physical activity, and exercise aspirations. Consistency was found in self-reported agreement with a series of holiday healthfulness statements, across time, holidays (Thanksgiving versus Christmas), and samples of respondents. The largest proportion of respondents displaying social desirability bias (SDB) were found in response to two statements, namely “I will consume more alcohol during the holiday season than at other times of the year” at (63–66%) and “I make it a New Year’s Resolution to lose weight” (60–63%). Cheap talk was tested as …


Perbedaan Karakter Hasil Tiga Varietas Ubi Jalar Berdasarkan Waktu Panen, Reza Prakoso Dwi Julianto, Edyson Indawan, Sukma Paramita Dec 2020

Perbedaan Karakter Hasil Tiga Varietas Ubi Jalar Berdasarkan Waktu Panen, Reza Prakoso Dwi Julianto, Edyson Indawan, Sukma Paramita

Jurnal Kultivasi

Ubi jalar (Ipomoea batatas L. (Lam)) merupakan jenis tanaman pangan yang mempunyai kandungan utama karbohidrat, selain itu juga mempunyai kandungan lain yang cukup tinggi seperti kalium, kalsium, protein, vitamin A, dan vitamin C. Masalah utama dalam pengembangan ubi jalar adalah rendahnya hasil dan kualitas hasil yang disebabkan oleh waktu panen yang tidak tepat. Pemanenan yang dilakukan secara tidak tepat akan menurunkan kuantitas dan kualitas hasil. Perbedaan waktu panen juga disebabkan perbedaan varietas tanaman. Tujuan penelitian ini adalah mengetahui waktu panen yang optimal dari masing-masing varietas ubi jalar agar mendapatkan produksi hasil yang optimal. Penelitian dilaksanakan pada bulan Maret – September …


Training Future Agriculture Professionals In Landowner–Tenant Conservation Decision-Making, Andrea Basche, Angela Carter Dec 2020

Training Future Agriculture Professionals In Landowner–Tenant Conservation Decision-Making, Andrea Basche, Angela Carter

Michigan Tech Publications, Part 1

The landowner–tenant relationship is important to the implementation of conservation on agricultural lands. Women own or co-own a significant portion of U.S. farmland yet are underrepresented in conservation research. The next generation of agriculture professionals can benefit from first-hand experience in assisting women landowners and their tenants in navigating the complexities of conservation decision-making. This article analyzes undergraduate student perceptions of landowner–tenant relationships in conservation management through their engagement in case studies with women landowner–tenant pairs in the Western Corn Belt. Student groups were asked to complete a management improvement plan that both incorporated the agronomic and conservation goals discussed …


Hormon Etilen Dan Auksin Serta Kaitannya Dalam Pembentukan Tomat Tahan Simpan Dan Tanpa Biji, Syariful Mubarok, Alin Robiah Al Adawiyah, Arin Rosmala, Fathi Rufaidah, Anne Nuraini, Erni Suminar Dec 2020

Hormon Etilen Dan Auksin Serta Kaitannya Dalam Pembentukan Tomat Tahan Simpan Dan Tanpa Biji, Syariful Mubarok, Alin Robiah Al Adawiyah, Arin Rosmala, Fathi Rufaidah, Anne Nuraini, Erni Suminar

Jurnal Kultivasi

Tomat merupakan salah satu komoditas tanaman hortikultura penting di Indonesia. Seiring dengan perkembangan teknologi, sudah banyak dikembangkan varietas tomat baru yang mempunyai karakter-karakter yang diinginkan antara lain tahan akan penyakit, produktivitas tinggi tinggi, kandungan nutrisi tinggi dan lain-lain. Penerapan teknologi melalui pendekatan hormonal sangat penting untuk menghasilkan jenis tomat baru, diantaranya adalah hormone etilen dan auksin. Kedua hormone tersebut sangat berpengaruh terhadap pertumbuhan dan hasil tomat khususnya untuk menghasilkan tomat yang adaptif pada kondisi lingkungan tercekam dan ketahanan simpan buah yang tinggi. Teknologi mutasi pada kedua hormone tersebut sudah dapat menghasilkan tomat yang diinginkan diantaranya adalah tomat iaa9-3 yang merupakan …


Kompatibilitas Persilangan Interspesifik Pada Spesies Cabai, Iklillah Maulidiyah Warda, Budi Waluyo Dec 2020

Kompatibilitas Persilangan Interspesifik Pada Spesies Cabai, Iklillah Maulidiyah Warda, Budi Waluyo

Jurnal Kultivasi

Peningkatan produksi cabai (Capsicum sp.) dapat dilakukan dengan melakukan diversifikasi jenis baru dari hasil persilangan antar spesies. Tujuan penelitian ialah untuk mempelajari kompatibilitas pada penyerbukan sendiri dan penyerbukan silang buatan interspesies. Penelitian dilaksanakan pada Januari 2020 – Juni 2020. Bahan yang digunakan ialah 4 spesies cabai. Persilangan disusun berdasarkan rancangan perkawinan dialil lengkap. Terdapat 16 kombinasi persilangan. Perbedaan karakter kuantitatif penyerbukan sendiri dan silang diuji menggunakan uji t 5%. Penyerbukan sendiri pada setiap spesies memiliki kompatibilitas penuh dengan persentase pembentukan buah yaitu 100%. Persilangan antara C. annuum Cann(B)-CYM2-151-3 x C. baccatum Cbac-09(S), C. frutescens Cfru-03(4) x C. annuum Cann(B)-CYM2-151-3 dan …


Student Perceptions Of An Inquiry‐Based Molecular Biology Lecture And Lab Following A Mid‐Semester Transition To Online Teaching, Jeremy L. Hsu, Melissa Rowland-Goldsmith Dec 2020

Student Perceptions Of An Inquiry‐Based Molecular Biology Lecture And Lab Following A Mid‐Semester Transition To Online Teaching, Jeremy L. Hsu, Melissa Rowland-Goldsmith

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The transition to online learning in spring 2020 was abrupt for both students and instructors. While many instructors moved to asynchronous classes, some institutions relied more heavily on synchronous online courses. Here, we evaluate student perceptions of an inquiry‐based molecular biology lecture and lab course following this transition by comparing student survey responses from spring 2019, when the lecture and lab were fully in person, to spring 2020, when the lecture and lab started in person before transitioning to a synchronous online format. Students were asked to identify the main factors that supported their learning in lecture and lab, characterize …


Prd-2 Directly Regulates Casein Kinase I And Counteracts Nonsense-Mediated Decay In The Neurospora Circadian Clock., Christina M Kelliher, Randy Lambreghts, Qijun Xiang, Christopher L. Baker, Jennifer J Loros, Jay C Dunlap Dec 2020

Prd-2 Directly Regulates Casein Kinase I And Counteracts Nonsense-Mediated Decay In The Neurospora Circadian Clock., Christina M Kelliher, Randy Lambreghts, Qijun Xiang, Christopher L. Baker, Jennifer J Loros, Jay C Dunlap

Faculty Research 2020

No abstract provided.


The Involvement Of Neuroimmune Cells In Adipose Innervation., Magdalena Blaszkiewicz, Elizabeth Wood, Sigi Koizar, Jake Willows, Ryan Anderson, Yu-Hua Tseng, James W Godwin, Kristy L Townsend Dec 2020

The Involvement Of Neuroimmune Cells In Adipose Innervation., Magdalena Blaszkiewicz, Elizabeth Wood, Sigi Koizar, Jake Willows, Ryan Anderson, Yu-Hua Tseng, James W Godwin, Kristy L Townsend

Faculty Research 2020

BACKGROUND: Innervation of adipose tissue is essential for the proper function of this critical metabolic organ. Numerous surgical and chemical denervation studies have demonstrated how maintenance of brain-adipose communication through both sympathetic efferent and sensory afferent nerves helps regulate adipocyte size, cell number, lipolysis, and 'browning' of white adipose tissue. Neurotrophic factors are growth factors that promote neuron survival, regeneration, and plasticity, including neurite outgrowth and synapse formation. Peripheral immune cells have been shown to be a source of neurotrophic factors in humans and mice. Although a number of immune cells reside in the adipose stromal vascular fraction (SVF), it …


Food Justice Saf 383, Michael Cerbo Dec 2020

Food Justice Saf 383, Michael Cerbo

Library Impact Statements

No abstract provided.


The Physiological Interaction Of Sleep Deprivation And Zoledronate On Distal Femur Trabecular Thickness Of Ovariectomized Rats, Erin Nolte, Frank Frisch, Oliver Lopez Dec 2020

The Physiological Interaction Of Sleep Deprivation And Zoledronate On Distal Femur Trabecular Thickness Of Ovariectomized Rats, Erin Nolte, Frank Frisch, Oliver Lopez

Health Sciences and Kinesiology Faculty Articles

Osteoporosis, a disease resulting in an increased risk of fracture due to compromised bone, affects 1 in 3 postmenopausal women. Discontinuities in the microarchitecture of bone, such as trabeculae, are seen in postmenopausal osteoporosis. This study aimed to evaluate how sleep deprivation affects the distal femur trabecular thickness of estrogen-deficient rats treated with Zoledronate. 29 ovariectomized Wistar female rats were separated into 4 groups. The control group (C) was housed in standard housing with a 12-hour light/dark cycle and was given an intravenous injection of 0.45 mL of 0.9% saline. The Zoledronate group (Z) were also housed in standard conditions …


Smokejumper Obituary: Daugherty, Michael Carl (Redding 1965), National Smokejumper Association Dec 2020

Smokejumper Obituary: Daugherty, Michael Carl (Redding 1965), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.


Antimicrobial Peptide Development: From Massively Parallel Peptide Sequencing To Bioinformatic Motif Identification, Alexander K. Erikson Dec 2020

Antimicrobial Peptide Development: From Massively Parallel Peptide Sequencing To Bioinformatic Motif Identification, Alexander K. Erikson

Theses and Dissertations

The isolation, purification, and clinical deployment of antibiotics is one of the major drivers of decrease in morbidity and mortality from infectious bacteria in the 20th century. The rapid, ubiquitous deployment of antibiotics encouraged swift development and distribution of antibiotic resistance. New, novel techniques, technologies, and ultimately therapeutic antimicrobial compounds will be required to counter the rise of antibiotic resistant microbes. Historically, mimicking naturally occurring compounds has been the most fruitful method for discovering new antibiotics; unsurprisingly, many recent efforts have focused on expanding the cultivation and detection of previously unknown microbes and compounds, respectively. Other techniques explore developing compounds …


A Morphological Phylogeny Of Odonatoptera: Examining Missing Data In A Group With A Lot Of "Naturally" Missing Data, Robert James Erickson Dec 2020

A Morphological Phylogeny Of Odonatoptera: Examining Missing Data In A Group With A Lot Of "Naturally" Missing Data, Robert James Erickson

Theses and Dissertations

Odonatopera exhibit a wide diversity of morphologies for an ancient group of winged insects. A morphological matrix of 463 characters is compiled for 347 extant and fossil representatives used in parsimony analyses, implemented in TNT, to document arrangements of taxonomic groups above the family level. Missing data and other challenges approaches implemented and interpretation of the results. We employ a novel approach to testing monophyly relative to quantities of missing data for each taxon. Phylogenetic reconstructions recover patterns of monophyly and trends based on missing data. We discuss the implications of our findings on missing data as well as limitations …


Intersectionality Shapes Adaptation To Social-Ecological Change, Anna Erwin, Zhao Ma, Ruxandra Popovici, Emma Patricia Salas O'Brien, Jonathan Bauchet, Nelly Ramirez Calderón, Glenn Roberto Arce Larrea Dec 2020

Intersectionality Shapes Adaptation To Social-Ecological Change, Anna Erwin, Zhao Ma, Ruxandra Popovici, Emma Patricia Salas O'Brien, Jonathan Bauchet, Nelly Ramirez Calderón, Glenn Roberto Arce Larrea

Department of Agricultural Economics Faculty Publications

People from across the Caylloma Province of Peru are adapting to social-ecological changes, such as decreasing water supplies and rapidly retreating glaciers, in different and unequal ways. In this study, we show how this inequality is intersectional; identities like gender and age compound and interact with systems of power to shape how people adapt to these changes at the individual, household, and district scales. We draw from 130 semi-structured interviews with agricultural actors and participant observations in district and regional meetings across four districts, to demonstrate how intersectionality shapes adaptation to social-ecological change. Our results show (1) what social-ecological changes …


A Rapid Spectrophotometric Assay For Quantifying Seed Coat Saponins In Quinoa, Sydney Diver Szabo Dec 2020

A Rapid Spectrophotometric Assay For Quantifying Seed Coat Saponins In Quinoa, Sydney Diver Szabo

Theses and Dissertations

Background and objectives: The commonly used afrosimetric foam-height method for quantifying saponins in quinoa is rapid but imprecise. A rapid UV/Vis method, utilizing the Liebermann-Burchard (LB) color reaction, was compared to the foam method across a range of saponin levels in washed and unwashed seed. Findings: A 6 min UV/Vis method provided greater precision and accuracy than the afrosimetric method at the lower saponin levels found in washed quinoa. The afrosimetric method did not differentiate saponin levels below 0.6 mg/mL but allows for useful relative comparisons of saponin content in unwashed quinoa where the foam height is large. Conclusions: The …


Criollo Cattle As A Strategy To Maintain Output Of Ecosystem Services Under A Changing Climate, Kari E. Veblen Dec 2020

Criollo Cattle As A Strategy To Maintain Output Of Ecosystem Services Under A Changing Climate, Kari E. Veblen

Funded Research Records

No abstract provided.


Exploration Of Pregnancy Recognition In Ruminants Using A Novel Type I Interferon Receptor Knockout Sheep Model, Christopher J. Davies Dec 2020

Exploration Of Pregnancy Recognition In Ruminants Using A Novel Type I Interferon Receptor Knockout Sheep Model, Christopher J. Davies

Funded Research Records

No abstract provided.


Heavy Metal Pb Stress On Germination And Growth Of 5 Clover Varieties, Zhenzhong Sun, Qiao Wei, Jun Yin Dec 2020

Heavy Metal Pb Stress On Germination And Growth Of 5 Clover Varieties, Zhenzhong Sun, Qiao Wei, Jun Yin

IGC Proceedings (1977-2023)

No abstract provided.


Maintaining Grassland Biodiversity While Controlling The Shrub Rhus Glabra, James Stubbendieck, Kay L. Kottas Dec 2020

Maintaining Grassland Biodiversity While Controlling The Shrub Rhus Glabra, James Stubbendieck, Kay L. Kottas

IGC Proceedings (1977-2023)

No abstract provided.


Eco-Politics Of Rangeland Management In The Hindu Kush-Himalayan Region: Articulating Ecology Into Food Sovereignty, Environmental Security, Development And Peace For A Sustainable World, Vir Singh Dec 2020

Eco-Politics Of Rangeland Management In The Hindu Kush-Himalayan Region: Articulating Ecology Into Food Sovereignty, Environmental Security, Development And Peace For A Sustainable World, Vir Singh

IGC Proceedings (1977-2023)

No abstract provided.


Desertification Reasons, Endangering And Tendency In China's Land, Yongjie Shi, Fuping Tian, Yuan Lu, Qing Song Dec 2020

Desertification Reasons, Endangering And Tendency In China's Land, Yongjie Shi, Fuping Tian, Yuan Lu, Qing Song

IGC Proceedings (1977-2023)

No abstract provided.


Biogeocenotechnology Of Restoration And Increase Of Efficiency For Degraded Pasture Ecosystems In Arid Regions Of Central Asia And Russia, Zebri Shamsutdinov, Nariman Shamsutdinov Dec 2020

Biogeocenotechnology Of Restoration And Increase Of Efficiency For Degraded Pasture Ecosystems In Arid Regions Of Central Asia And Russia, Zebri Shamsutdinov, Nariman Shamsutdinov

IGC Proceedings (1977-2023)

No abstract provided.