Life Sciences Commons^™

Rigorous Innovation: How Neuroscience Shapes Our View Of Creativity, Emma Hahn

The Synapse: Intercollegiate science magazine

No abstract provided.

Venturing Into The Unknown: The First Human Head Transplant, Christine Craddock

The Synapse: Intercollegiate science magazine

No abstract provided.

Diy Genetics: The Ethics Of Crispr, Leah Treidler

The Synapse: Intercollegiate science magazine

No abstract provided.

Gut Check: How Microbiome Research Is Reshaping Our View Of Bacteria In Human Health, Rachel Reardon

The Synapse: Intercollegiate science magazine

No abstract provided.

Dr. Chie Sakakibara: Collaborative Research With The Iñupiaq People In Utqiagvik, Alaska, Lauren Rhodes

The Synapse: Intercollegiate science magazine

No abstract provided.

Revisiting A Forgotten Epidemic: West Africa’S Largest Ebola Outbreak Three Years Later, Jayla Johnson

The Synapse: Intercollegiate science magazine

No abstract provided.

Crossword Corner, Rachel Dan

The Synapse: Intercollegiate science magazine

No abstract provided.

Paul Rich: Building Offshore Windfields, Monica Dix

The Synapse: Intercollegiate science magazine

No abstract provided.

The Curious Case Of The Reindeer In The Tundra, Eleda Fernald

The Synapse: Intercollegiate science magazine

No abstract provided.

Whale You At? The Influence Of Solar Storms On Frequency Of Whale Strandings In The North Sea, Gaby Sarri-Tobar

The Synapse: Intercollegiate science magazine

No abstract provided.

Painting The Inner Landscape Of The Mind: Exploring The Mental Maps Of Memory And Imagination Through Science And Literature, Ally Fulton

The Synapse: Intercollegiate science magazine

No abstract provided.

More Than Just A Dream: Understanding The Mechanics And Neuroscience Of Dreaming From Inception, Jayla Johnson

The Synapse: Intercollegiate science magazine

No abstract provided.

Falling Into A State Deeper Than Sleep: How Melatonin Affects The Body, Carson Mccann

The Synapse: Intercollegiate science magazine

No abstract provided.

Redirecting Zika: A Treatment For Brain Cancer?, Rachael Branscomb

The Synapse: Intercollegiate science magazine

No abstract provided.

Front Matter

The Synapse: Intercollegiate science magazine

No abstract provided.

Mosquito Maladies: Genetic Manipulation Of Mosquitoes Leads To Potential Solution To The Spread Of Malaria, Mariam Saied

The Synapse: Intercollegiate science magazine

No abstract provided.

My Grandmother’S Memories: How Epigenetics Are Changing Our Understanding Of Heritability, Rachel Reardon

The Synapse: Intercollegiate science magazine

No abstract provided.

The Monsters Lurking In Oberlin’S Science Center’S Couches: Flame Retardant Treated Furniture, Jane Sedlak

The Synapse: Intercollegiate science magazine

No abstract provided.

Expanding The Job Of A Scientist: A Call For Explicit Writing Instruction In Undergraduate Stem Education, Ally Fulton

The Synapse: Intercollegiate science magazine

No abstract provided.

Can We Educate Better? Active Learning And Underrepresentation In Stem, Kepler Mears

The Synapse: Intercollegiate science magazine

No abstract provided.

Variation In Models For Simple Dynamic Structure-Soil-Structure Interaction Problems, L. V. Andersen, A. Peplow, P. Bucinskas, P. Persson, K. Persson

All Works

© 2017 The Authors. Published by Elsevier Ltd. To account for dynamic cross-coupling of structures via the soil, a computational model must be accurate enough to provide the correct overall behaviour of the scattered wave field. However, simplicity is also important when a model should be used for design purposes, especially in the early design stages and feasibility studies. The paper addresses the accuracy of simple models in which an array of structures is simplified into blocks placed on the ground surface or embedded within the soil. Comparisons are made between models that account or do not account, in a …

Evidence Of A Perilipin 5 Splice Variant, Brodie Ranzau

Undergraduate Honors Thesis Projects

Alternative splicing occurs throughout the human genome, leading to multiple proteins from a single gene. The resulting proteins can be nearly identical or vastly different in how they function. Alternative splicing within the perilipin family has been observed in perilipins 1 and 3, giving rise to proteins with varying functions. In the course of our studies on perilipin 5, an immunoblot signal was observed that corresponded to an approximately 35 kDa protein. Western blot analysis of this protein has revealed its expression in C2C12 cultured myoblasts and in heart and liver mouse tissue. Further analysis of perilipin 5 cDNA through …

Expression, Purification And Characterization Of Lysine Methyltransferase Smyd5, Wen Xue

Wayne State University Theses

Methylation of histones and non-histone proteins play vital roles in numerous cellular processes including gene expression regulation and DNA damage response. The identifications of methyltransferase SMYD protein family are not well characterized. SMYD5 is a unique and critical member of SMYD family involved in immune response, stem cell renew, hematopoiesis regulation and cancer metastasis. Understanding its function and structure is monumental to human disease. With the achievement of SMYD5 expression and purification, the association between SMYD5 and its substrate histone H4 has been investigated. While possessing a poly-E tail instead of the TPR domain included in other members, SMYD5 is …

Comparison Of Lumbo-Pelvic Kinematics During Trunk Forward Bending And Backward Return Between Patients With Acute Low Back Pain And Asymptomatic Controls, Iman Shojaei, Elizabeth G. Salt, Quenten L. Hooker, Linda R. Van Dillen, Babak Bazrgari

Biomedical Engineering Faculty Publications

Background—Prior studies have reported differences in lumbo-pelvic kinematics during a trunk forward bending and backward return task between individuals with and without chronic low back pain; yet, the literature on lumbo-pelvic kinematics of patients with acute low back pain is scant. Therefore, the purpose of this study was set to investigate lumbo-pelvic kinematics in this cohort.

Methods—A case-control study was conducted to investigate the differences in pelvic and thoracic rotation along with lumbar flexion as well as their first and second time derivatives between females with and without acute low back pain. Participants in each group completed one …

Amphibians And Reptiles Of The State Of Chihuahua, Mexico, With Comparisons With Adjoining States, J. A. Lemos-Espinal, Geoffrey R. Smith, G. A. Woolrich-Pina, A. Cruz

Faculty Publications

No abstract provided.

Status Reports Of The Fisheries And Aquatic Resources Of Western Australia 2015/16. State Of The Fisheries, W.J Fletcher, M.D. Mumme, F J. Webster

Status Reports of the Fisheries and Aquatic Resources

As part of the transition to ultimately using a web based, hierarchical interface, this years’ edition of the Status Reports of the Fisheries and Aquatic Resources of Western Australia 2015/16 is adopting a more streamlined format. These changes include updates to the summary table which, in addition to displaying the stock and fishery performance levels, now includes current performance and risk levels for each of the other EBFM outcomes (e.g. bycatch, listed species, economics etc.).

Physical Determinants Of Division 1 Collegiate Basketball, Women’S National Basketball League And Women’S National Basketball Association Athletes: With Reference To Lower Body Sidedness, T Spiteri, M Binetti, A Scanlan, V Dalbo, F Dolci, C Specos

Health Sciences Papers and Journal Articles

In female basketball the assumed components of success include power, agility, and the proficiency at executing movements using each limb. However, the importance of these attributes in discriminating between playing levels in female basketball have yet to be determined. The purpose of this study was to compare lower body power, change of direction (COD) speed, agility, and lower-body sidedness between basketball athletes participating in Division 1 Collegiate basketball (United States), Women's National Basketball League (WNBL) (Australia), and Women's National Basketball Association (WNBA) (United States). Fifteen female athletes from each league (N = 45) completed a double and single leg counter-movement …

Patient Evaluation Of Emotional Comfort Experienced (Peece): Developing And Testing A Measurement Instrument, A Williams, L Lester, C Bulsara, A Petterson, K Bennett, E Allen, D Joske

Health Sciences Papers and Journal Articles

Objectives: The Patient Evaluation of Emotional Comfort Experienced (PEECE) is a 12-item questionnaire which measures the mental well-being state of emotional comfort in patients. The instrument was developed using previous qualitative work and published literature.

Design: Instrument development.

Setting: Acute Care Public Hospital, Western Australia.

Participants: Sample of 374 patients.

Interventions: A multidisciplinary expert panel assessed the face and content validity of the instrument and following a pilot study, the psychometric properties of the instrument were explored.

Main outcome measures: Exploratory and confirmatory factor analysis assessed the underlying dimensions of the PEECE instrument; Cronbach’s α was used to determine the …

Lack Of Evidence For Decreased Protein Stability In The 2397 (Met) Haplotype Of The Leucine Rich Repeat Kinase 2 Protein Implicated In Parkinson’S Disease, Ryan S. Anderton, Lauren Hill, Rhiannon Morris, Frank L. Mastaglia, Wayne Greene, Sherif Boulos

Health Sciences Papers and Journal Articles

Missense mutations in the leucine rich repeat kinase 2 (LRRK2) gene are the leading genetic cause of autosomal dominant familial Parkinson’s disease. We previously reported that two mutations within the ROC domain, namely R1441C and A1442P, exhibit increased protein degradation leading to lowered steady state LRRK2 protein levels in HEK293 cells. More recently, the common WD40 domain LRRK2 haplotype, Met2397, which is a risk factor for Crohn’s disease, has been shown to lower steady state protein levels in HEK293 cells. In view of recent evidence implicating LRRK2 and inflame-mation in PD, we investigated the effects of Met2397 on LRRK2 expression, …

Changes In Fatty Acid Composition Of Human Milk In Response To Cold-Like Symptoms In The Lactating Mother And Infant, Andrew S. Gardner, Ibrahim A. Rahman, Ching T. Lai, Anna Hepworth, Naomi Trengove, Peter E. Hartmann, Donna T. Geddes

Health Sciences Papers and Journal Articles

Infants rely on their innate immune systems to protect them from infection. Human milk (HM) contains fatty acids (FAs) and monoacylglycerols that are known to exhibit antiviral and antibacterial properties in vitro. The specific fat content of HM may potentially affect the efficacy of this antimicrobial activity. This preliminary study investigates whether the proportions of FA in HM change in response to infections, leading to cold-like symptoms in the mother or infant. Milk samples were obtained from mothers (n = 26) when they and their infants were healthy, and when mother, infant, or both suffered cold-like symptoms. The milk was …