Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (21168)
- Agriculture (18892)
- Animal Sciences (18077)
- Biology (17123)
- Plant Sciences (16597)
-
- Physical Sciences and Mathematics (15559)
- Social and Behavioral Sciences (12227)
- Ecology and Evolutionary Biology (10164)
- Medical Sciences (9893)
- Medical Specialties (9865)
- Bioinformatics (8970)
- Environmental Sciences (8390)
- Entomology (7706)
- Biomedical Informatics (7414)
- Oncology (7122)
- Education (5913)
- Biochemistry, Biophysics, and Structural Biology (5816)
- Genetics and Genomics (5565)
- Communication (4932)
- Forest Sciences (4747)
- Agronomy and Crop Sciences (4605)
- Arts and Humanities (4445)
- Medical Genetics (4423)
- Agricultural Science (4340)
- Genetic Phenomena (4180)
- Biodiversity (4094)
- Journalism Studies (4088)
- Marine Biology (4031)
- Ornithology (3914)
- Institution
-
- University of Nebraska - Lincoln (32668)
- Utah State University (8219)
- The Texas Medical Center Library (8023)
- University of Kentucky (3880)
- Department of Primary Industries and Regional Development, Western Australia (3392)
-
- Colby College (3075)
- South Dakota State University (2291)
- Old Dominion University (1968)
- Western Kentucky University (1757)
- University of Arkansas, Fayetteville (1449)
- International Centre of Insect Physiology and Ecology (1443)
- City University of New York (CUNY) (1442)
- Nova Southeastern University (1411)
- University of Texas at Arlington (1286)
- California Polytechnic State University, San Luis Obispo (1260)
- North Carolina Agricultural and Technical State University (1118)
- University of South Florida (1077)
- University of Texas Rio Grande Valley (1062)
- WellBeing International (1044)
- Chapman University (1036)
- Technological University Dublin (1028)
- Dartmouth College (944)
- Tennessee State University (916)
- Portland State University (905)
- University of Montana (884)
- Marquette University (876)
- Wright State University (873)
- University of Nevada, Las Vegas (821)
- Stephen F. Austin State University (811)
- Edith Cowan University (803)
- Keyword
-
- Humans (6360)
- Agricultural newspapers (3000)
- American newspapers (3000)
- Central Maine (3000)
- Maine history (3000)
-
- Popular literature (3000)
- Animals (2763)
- 19th century newspapers (2670)
- Female (2465)
- Male (2036)
- Western Australia (1897)
- Mice (1683)
- Adult (1168)
- Middle Aged (1120)
- Aged (1020)
- Agriculture (977)
- Biology (934)
- Publications (848)
- Grains and field crops (813)
- Climate change (740)
- Neoplasms (735)
- University of Nebraska (726)
- Tumor (719)
- Cooperative Extension (679)
- Mutation (661)
- Nebraska Cooperative Extension (659)
- Utah State University Extension (644)
- Nutrition (596)
- Genetics (592)
- Management (574)
- Publication Year
- Publication
-
- Faculty, Staff and Student Publications (7587)
- Faculty Publications (2622)
- The Waterville Mail (Waterville, Maine) (2161)
- University of Nebraska-Lincoln Extension: Historical Materials (2063)
- All Current Publications (1884)
-
- Biology Faculty Publications (1771)
- Department of Agronomy and Horticulture: Faculty Publications (1713)
- Biological Sciences Faculty Publications (1571)
- United States Department of Agriculture Wildlife Services: Staff Publications (1530)
- Nebraska Bird Review (1477)
- All Peer-Reviewed Publications (1443)
- Insecta Mundi (1416)
- United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications (1363)
- Publications and Research (1267)
- Department of Animal Science: Faculty Publications (1243)
- Nebraska Beef Cattle Reports (1237)
- Documents (1144)
- Jessie Maye Smith Birds and Watchers Columns Collection (1036)
- Department of Entomology: Faculty Publications (1015)
- School of Biological Sciences: Faculty Publications (945)
- Dartmouth Scholarship (938)
- Aspen Bibliography (922)
- Harold W. Manter Laboratory of Parasitology: Faculty Publications (906)
- Experimental Summaries - Plant Research (885)
- The Eastern Mail (Waterville, Maine) (839)
- Articles (812)
- Biological Sciences Faculty Research and Publications (757)
- All Archived Publications (746)
- Marine Science Faculty Publications (736)
- Biology Faculty Publications and Presentations (708)
Articles 241 - 270 of 118197
Full-Text Articles in Life Sciences
Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye
Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye
Faculty Publications
Sodium barium lutetium borate NaBaLu(BO3)2 crystals were synthesized using a high-temperature solution method. The crystal structure of this layered orthoborate is described and corresponds to that of an extensive orthoborates family, NaBaR(BO3)2 (R = Sc, Y, Yb, Tb – Lu). NaBaLu(BO3)2 was doped by Eu3+ and Tb3+ to explore its performance as a host material and to investigate the luminescent properties of the Eu3+ and Tb3+ doped materials. The emission spectra of the NaBaLu(BO3)2:Ln (Ln = Eu, Tb) crystals are presented. The most …
The Massbank Contributions Of The Mfam Collaboration, Anusha Ahlendorf, Asaph Aharoni, Khabat Vahabi, Tillmann G. Fischer, Pierre Marie Allard, Megan Augustin, Ulschan Bathe, David Broadhurst, Corey Broeckling, Joerg Buescher, Adrian Covaci, Katyeny Manuela Da Silva, Ric C.H. De Vos, Micha Gracianna Devi, Stefanie Döll, Maximilian Frey, Andrej Frolov, Emmanuel Gaquerel, Vasuk Gautam, Esteban Charria-Girón, Alain Goossens, Jeremy Grosjean, Maria Halabalaki, Elias Iturrospe, Kim Kultima, Stephanie Herman, Toni M. Kutchan, Romain Larbat, René Meier, Eleni V. Mikropoulou, Gregory Mouille, Luca Nicolotti, Nir Shahaf, François Perreau, Pierre Pétriacq, Michael Reichelt, Stacey N. Reinke, Rani Robeyns, Alena Soboleva, Otmar Spring, Akshai Parakkal Sreenivasan, Alain Tissier, Jean Chrisologue Totozafy, Hiroshi Tsugawa, Josep Valls-Fonayet, Maria Van De Lavoir, Justin J.J. Van Der Hooft, Fredd Vergara, David Wishart, Ludger A. Wessjohann, Jean-Luc Wolfender, Jörg Ziegler, Gerd Ulrich Balcke, Steffen Neumann
The Massbank Contributions Of The Mfam Collaboration, Anusha Ahlendorf, Asaph Aharoni, Khabat Vahabi, Tillmann G. Fischer, Pierre Marie Allard, Megan Augustin, Ulschan Bathe, David Broadhurst, Corey Broeckling, Joerg Buescher, Adrian Covaci, Katyeny Manuela Da Silva, Ric C.H. De Vos, Micha Gracianna Devi, Stefanie Döll, Maximilian Frey, Andrej Frolov, Emmanuel Gaquerel, Vasuk Gautam, Esteban Charria-Girón, Alain Goossens, Jeremy Grosjean, Maria Halabalaki, Elias Iturrospe, Kim Kultima, Stephanie Herman, Toni M. Kutchan, Romain Larbat, René Meier, Eleni V. Mikropoulou, Gregory Mouille, Luca Nicolotti, Nir Shahaf, François Perreau, Pierre Pétriacq, Michael Reichelt, Stacey N. Reinke, Rani Robeyns, Alena Soboleva, Otmar Spring, Akshai Parakkal Sreenivasan, Alain Tissier, Jean Chrisologue Totozafy, Hiroshi Tsugawa, Josep Valls-Fonayet, Maria Van De Lavoir, Justin J.J. Van Der Hooft, Fredd Vergara, David Wishart, Ludger A. Wessjohann, Jean-Luc Wolfender, Jörg Ziegler, Gerd Ulrich Balcke, Steffen Neumann
Research outputs 2022 to 2026
Introduction: The analysis of metabolic profiles using high resolution mass spectrometry (MS) data provides deep insights into biological processes. In metabolomics, MS analysis generates a large number of features that represent metabolites. However, identifying specific metabolites from these features can be challenging. One of the major bottlenecks in the metabolomics field is the identification of MS features, which is a prerequisite for any biochemical interpretation. By identifying similarities and differences within a metabolite family (mFam), evaluating MS features at the metabolite family level can help assigning functional roles to individual MS features. These data can help interpreting metabolic pathways and …
Odyssey To The Extraordinary: Living Our Land Grant Mission And Beyond, Jeffrey P. Gold, Katherine S. Ankerson, Tiffany Heng-Moss
Odyssey To The Extraordinary: Living Our Land Grant Mission And Beyond, Jeffrey P. Gold, Katherine S. Ankerson, Tiffany Heng-Moss
Institute of Agriculture and Natural Resources: Institute Publications
Presents a strategy intended to guide future directions for the University of Nebraska-Lincoln's (UNL) Institute of Agriculture and Natural Resources (IANR) including issues related to governance, funding, organizational structure, and strategic alignment within UNL and the University of Nebraska system.
B.R. Wells Arkansas Rice Research Studies 2025, J. Hardke, X. Sha, N. Bateman
B.R. Wells Arkansas Rice Research Studies 2025, J. Hardke, X. Sha, N. Bateman
Arkansas Agricultural Experiment Station Research Series
Arkansas is the leading rice producer in the United States. The state represents 45.2% of total U.S. rice production and 45.7% of the total acres planted to rice in 2025. Rice cultural practices vary across the state and across the U.S. However, these practices are also dynamic and continue to evolve in response to changing political, environmental, and economic times. This survey was initiated in 2002 to monitor and record changes in the way Arkansas rice producers approach their livelihood. The survey was conducted by polling county extension agents in each of the counties in Arkansas that produce rice. Questions …
Nh Dfl - 25 Years Of Hwa - Peterborough_2026_Aug_11, Ryan Crandall
Nh Dfl - 25 Years Of Hwa - Peterborough_2026_Aug_11, Ryan Crandall
UNH Cooperative Extension
No abstract provided.
Concerns With The Statistical Analysis In “Effect Of Combined Glp-1 Analogue And Bupropion/Naltrexone On Weight Loss: A Retrospective Cohort Study”, Thirupathi Reddy Mokalla, Henry T Robertson, Sherri Pals, David B Allison
Concerns With The Statistical Analysis In “Effect Of Combined Glp-1 Analogue And Bupropion/Naltrexone On Weight Loss: A Retrospective Cohort Study”, Thirupathi Reddy Mokalla, Henry T Robertson, Sherri Pals, David B Allison
Children’s Nutrition Research Center Staff Publications
No abstract provided.
All-Cause And Cause-Specific Mortality In Gambling Disorder: Evidence From A Nation-Wide Matched And Sibling Cohort Study In Taiwan, Yang-Chieh Brian Chen, Chih-Wei Hsu, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai
All-Cause And Cause-Specific Mortality In Gambling Disorder: Evidence From A Nation-Wide Matched And Sibling Cohort Study In Taiwan, Yang-Chieh Brian Chen, Chih-Wei Hsu, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai
Children’s Nutrition Research Center Staff Publications
Background and aims: Gambling disorder (GD) has been linked to suicidal ideation and suicide deaths; however, evidence on all-cause and cause-specific mortality-particularly in Asian populations-remains limited. Using a retrospective cohort study based on nationwide matched and sibling cohort, we investigated all-cause and cause-specific mortality risk in patients with GD.
Design, setting and participants: A retrospective cohort study was conducted using 2000-2022 data from Taiwan's National Health Insurance Research Database. A cohort of 961 individuals diagnosed with GD was identified. An age- and sex-matched control cohort (n = 3,844) and an unaffected sibling cohort (n = 675) were constructed. Cumulative survival …
Hyperadhesive Von Willebrand Factor Contributes To Pathogenesis Of Preeclampsia, Yajuan Wang, Chenyu Wang, Katie L Houck, Xiaoli Gao, Yuanyuan Chen, Xin Xu, Xue Zhao, Miguel A Cruz, Shu Zhang, Chester Q Li, Fengxia Xue, Min Li, Swati Shree, Jing-Fei Dong, Cha Han
Hyperadhesive Von Willebrand Factor Contributes To Pathogenesis Of Preeclampsia, Yajuan Wang, Chenyu Wang, Katie L Houck, Xiaoli Gao, Yuanyuan Chen, Xin Xu, Xue Zhao, Miguel A Cruz, Shu Zhang, Chester Q Li, Fengxia Xue, Min Li, Swati Shree, Jing-Fei Dong, Cha Han
Children’s Nutrition Research Center Staff Publications
Background: Preeclampsia is the most common complication of pregnancy, significantly affecting maternal and fetal health, and is characterized by placental and systemic endotheliopathy. Patients with preeclampsia have elevated levels of VWF (von Willebrand Factor), which is associated with poor clinical outcomes. However, whether VWF serves as a marker for endotheliopathy or contributes to the pathogenesis of preeclampsia remains poorly understood.
Methods: We investigated the role of hyperadhesive VWF in the development of preeclampsia by studying patients, evaluating mouse models, and performing in vitro experiments.
Results: We show that patients develop VWF- and fibrin-rich thrombosis in the placenta and have significantly …
Full-Fat Dairy Milk Vs. Isolated Free Nutrient Blend On Postprandial Protein Metabolism And Inflammatory Markers In Adults With Overweight And Obesity, Takeshi M. Barnes, Zan Zupancic, Max T. Deutz, Andrew T. Askow, Colleen F. Mckenna, Jonathan A. Aguilera, Cassidy T. Tinline-Goodfellow, Alexander V. Ulanov, Jared W. Willard, Daniel W. D. West, Michael De Lisio, Daniel R. Moore, Nicholas A. Burd
Full-Fat Dairy Milk Vs. Isolated Free Nutrient Blend On Postprandial Protein Metabolism And Inflammatory Markers In Adults With Overweight And Obesity, Takeshi M. Barnes, Zan Zupancic, Max T. Deutz, Andrew T. Askow, Colleen F. Mckenna, Jonathan A. Aguilera, Cassidy T. Tinline-Goodfellow, Alexander V. Ulanov, Jared W. Willard, Daniel W. D. West, Michael De Lisio, Daniel R. Moore, Nicholas A. Burd
Kinesiology & Sport Management Scholarship
Excess adiposity is linked to anabolic resistance by blunting the postprandial myofibrillar protein synthetic response to protein ingestion. Full-fat dairy milk may overcome this resistance via a matrix combining high-quality protein with anti-inflammatory lipids. Therefore, we compared the effects of ingesting full-fat dairy milk versus a non-dairy macronutrient match isolated blend on the regulation of postprandial myofibrillar and mitochondrial protein synthesis rates and markers of systemic (i.e., IL-6 and TNF-α) and muscle-related inflammation (i.e., NF-κB, NLRP3, TLR4, and MyD88). Twenty-two obese and overweight adult males and females (BMI = 31.1 ± 3.7 kg m−2; aged 35.3 ± 13.2 y) were …
Economic Contribution Of The Agricultural Sector To The Arkansas Economy In 2024, Frank Seo, Luke Pullo
Economic Contribution Of The Agricultural Sector To The Arkansas Economy In 2024, Frank Seo, Luke Pullo
AAES Research Reports and Research Bulletins
This report is the nineteenth in a series that examines agriculture’s economic contribution to the Arkansas economy. The total economic contribution of agriculture (direct, indirect, and induced effects) on value added, employment, and labor income was estimated with the Impact Analysis for Planning System (IMPLAN) for the most recent year available, 2024.
Evaluating The Motivations Of Participants In Online Equine Extension Courses, Sarah Vos
Evaluating The Motivations Of Participants In Online Equine Extension Courses, Sarah Vos
Department of Animal Science: Dissertations, Theses, and Student Research
Traditional program evaluations emphasize participant demographics, knowledge gain, behavior change, and program impact. However, evaluating participant motivation can provide addition insight into why participants enroll in extension programs and help explain participant engagement and persistence throughout a program. The purpose of this study was to evaluate participant motivation in two online equine extension courses and examine potential relationships between motivation, demographics, and course delivery method, and describe participant engagement in Virtual Horse Judging Camp (VHJC). This cross-sectional study utilized convenience sampling of participants in two online equine extension courses, Horse Adult Leader Training and Educational Resource (HALTER) and VHJC. The …
Melatonin-Functionalized Silver Nanoparticles Enhance Salinity Tolerance In Brassica Juncea By Modulating Antioxidant Defence And Growth Physiology, Mohini Yadav, Manar Fawzi Bani Mfarrej, Vikash Kumar, Ankita Singh, Faheem Ahmad, Saurabh C. Saxena
Melatonin-Functionalized Silver Nanoparticles Enhance Salinity Tolerance In Brassica Juncea By Modulating Antioxidant Defence And Growth Physiology, Mohini Yadav, Manar Fawzi Bani Mfarrej, Vikash Kumar, Ankita Singh, Faheem Ahmad, Saurabh C. Saxena
All Works
Soil salinity is a major abiotic stress that severely limits plant growth and productivity by inducing osmotic stress, oxidative damage, and ionic imbalances. The present study evaluated the potential of melatonin-mediated silver nanoparticles (Mel AgNPs) to enhance salinity stress tolerance in Brassica juncea. Pot experiments were conducted using 21-day-old plants exposed to salinity stress and treated with Mel AgNPs at different concentrations (50 and 100 mg L⁻¹) through both root application and foliar spray. Morphological, physiological, and biochemical responses were assessed 48 h after nanoparticle exposure. Salinity stress markedly increased lipid peroxidation and hydrogen peroxide accumulation while suppressing antioxidant defence. …
Validated Crispr/Cas9 Guide Rnas Targeting Neurodevelopmental Genes In The Tunicate Ciona Robusta, Sydney Popsuj, Tenzin Kalsang, Eduardo D. Gigante
Validated Crispr/Cas9 Guide Rnas Targeting Neurodevelopmental Genes In The Tunicate Ciona Robusta, Sydney Popsuj, Tenzin Kalsang, Eduardo D. Gigante
Faculty Articles
The tunicate Ciona robusta provides a powerful and simplified model for dissecting the genetic control of developmental and cell biology. With a larval CNS composed of just over 200 neurons and sensory cells, it has also emerged as a model organism for neurobiology and the development of the nervous system. Although CRISPR/ Cas9-mediated mutagenesis is now routinely used in Ciona as an important technique used to interrogate gene function in diverse biological processes, validated single-guide RNAs (sgRNAs) have yet to be validated for several key neural genes. Here, we report the design and experimental validation of 25 novel sgRNAs targeting …
Pre-Post Changes In Physiological, Cognitive, And Motivational Outcomes Following An Active Video Game Intervention In Adolescents And Adults: A Pilot Study, Ashley Williams, Danielle D. Wadsworth, Thaangiah Geetha
Pre-Post Changes In Physiological, Cognitive, And Motivational Outcomes Following An Active Video Game Intervention In Adolescents And Adults: A Pilot Study, Ashley Williams, Danielle D. Wadsworth, Thaangiah Geetha
Publications
Active video games (AVG) are emerging as a promising home-based strategy to increase physical activity by integrating movement into interactive gameplay. However, evidence remains limited regarding their effectiveness across physiological, cognitive, and motivational outcomes in adolescents and adults within household settings.
Why Technical Readiness Is Not Enough: Institutional Barriers To Full Harvest Strategy Adoption In The International Pacific Halibut Commission, Evelyn Roozee, Owen Temby, Gordon M. Hickey
Why Technical Readiness Is Not Enough: Institutional Barriers To Full Harvest Strategy Adoption In The International Pacific Halibut Commission, Evelyn Roozee, Owen Temby, Gordon M. Hickey
School of Earth, Environmental, & Marine Sciences Faculty Publications
Harvest strategies are increasingly promoted as a mechanism to reduce political discretion and align fisheries management with pre-agreed scientific objectives. While substantial progress has been made in tuna regional fisheries management organizations (RFMOs), non-tuna RFMOs have lagged behind. Existing research has focused primarily on technical modeling challenges, with comparatively limited attention to the governance dynamics shaping adoption. Using the International Pacific Halibut Commission (IPHC) as an instrumental case study, we examine the progress and delays in the development of a harvest strategy policy (HSP) through semi-structured interviews and participant observation. We find that the IPHC successfully addressed commonly cited barriers, …
Quaking Aspen On Cedar Mountain, Utah: Status And Update, Jaycee Cappaert, Larissa L. Yocom, Paul C. Rogers, Darren J. Mcavoy, R. Justin Derose
Quaking Aspen On Cedar Mountain, Utah: Status And Update, Jaycee Cappaert, Larissa L. Yocom, Paul C. Rogers, Darren J. Mcavoy, R. Justin Derose
Wildland Resources Student Research
Quaking aspen forests are important communities in the western United States where they provide preferential food and habitat for animals, limit wildfires from spreading, and have favorable aesthetics, among other things. Their putative decline is an issue for ecology and management. We remeasured the aspen population on Cedar Mountain, Utah, to assess changes to its condition since it was originally measured in 2008 and laid the groundwork for continued aspen monitoring on Cedar Mountain. Our objectives were to compare current metrics of stand structure and composition, mortality, crown dieback, bole damage, regeneration, and recruitment, to those of the original inventory. …
Alfred Russel Wallace Notes 42: How Accurate Are The Transcriptions Presented At The Alfred Russel Wallace Page Website?, Charles H. Smith
Alfred Russel Wallace Notes 42: How Accurate Are The Transcriptions Presented At The Alfred Russel Wallace Page Website?, Charles H. Smith
Faculty/Staff Personal Papers
A look is taken at the level of accuracy displayed by the transcriptions of Wallace writings offered at the Alfred Russel Wallace Page website, as determined by a ChatGPT analysis.
Summaries Of Arkansas Cotton Research 2025, Fred M. Bourland
Summaries Of Arkansas Cotton Research 2025, Fred M. Bourland
Arkansas Agricultural Experiment Station Research Series
Planted cotton acreage in Arkansas decreased in 2025 to 520,000 acres compared to 650,000 planted acres in 2024. Arkansas producers harvested 515,000 acres, which was a decrease of 125,000 acres from the 640,000 acres harvested in 2024 (https://www.nass.usda.gov/Quick_Stats/Ag_Overview/stateOverview.php?state=Arkansas&year=2025). The 515,000 harvested acres ranked Arkansas third nationally, trailing only Texas and Georgia in harvested acres (https://esmis.nal.usda.gov/sites/default/release-files/795725/cropan26.pdf). The average cotton yield, as reported by the USDA, was 1,239 lb lint/ac, which ranked fourth nationally, behind California, Louisiana, and Arizona. Arkansas farmers produced an estimated 1.329 million bales, which is a decrease from 1.788 million bales produced in 2024. This production still ranks …
Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Major Depressive Disorder, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Katja Beesdo-Baum, Mark A. Bellgrove, Vivek Benegal, Anderson M. Winkler
Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Major Depressive Disorder, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Katja Beesdo-Baum, Mark A. Bellgrove, Vivek Benegal, Anderson M. Winkler
Human Genetics Publications
Background: Externalizing and internalizing disorders are common in youth but are often studied separately, preventing researchers from identifying shared (i.e., transdiagnostic) alterations in brain structure. Using data from the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium, we conducted a mega-analysis to identify shared and distinct cortical and subcortical brain alterations across internalizing (anxiety disorders and depression) and externalizing (attention-deficit/hyperactivity disorder [ADHD] and conduct disorder [CD]) disorders in youth.
Methods: 3D T1-weighted magnetic resonance imaging data from youths (age range 4-21 years) with anxiety disorders (n = 1044), depression (n = 504), ADHD (n = 1317), and CD (n = 1172) …
Colocalization Of Eqtls With Type 2 Diabetes And Glycemic Traits Using Whole-Genome Sequences In Diverse Populations From The Nhlbi Trans-Omics In Precision Medicine (Topmed) Program, Ningyuan Wang, Daniel A. Dicorpo, Yixin Zhang, Erica Kleinbrink, Donna K. Arnett, John Barnard, John Blangero, Joanne E. Curran, Ravindranath Duggirala
Colocalization Of Eqtls With Type 2 Diabetes And Glycemic Traits Using Whole-Genome Sequences In Diverse Populations From The Nhlbi Trans-Omics In Precision Medicine (Topmed) Program, Ningyuan Wang, Daniel A. Dicorpo, Yixin Zhang, Erica Kleinbrink, Donna K. Arnett, John Barnard, John Blangero, Joanne E. Curran, Ravindranath Duggirala
Human Genetics Publications
Large-scale multiancestry genome-wide association studies have identified hundreds of loci associated with type 2 diabetes (T2D) and glycemic traits, yet imputed genotyping arrays limit the detection of low-frequency and rare variants. Whole-genome sequencing (WGS) offers a more complete view of genetic variation, especially across diverse populations. We analyzed high-coverage (38×) WGS data from 21,913 T2D case subjects, 61,036 control subjects, and up to 50,011 individuals with no diabetes with fasting glucose, fasting insulin, and HbA1c from the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Program. We performed single-variant association testing, conditional analysis, fine-mapping, and Bayesian colocalization to …
Associations Of Polygenic Risk Scores For Type 2 Diabetes With Metabolic Measures In Pacific Islanders From Guam And Saipan, Maria J. Ramirez-Luzuriaga, Saied Safabakhsh, Rasol Salehi, Sayuko Kobes, Tanisha F. Aflague, Jenny Duenas Sarmiento, Joanne Curran, Robert G. Nelson, Jeffrey M. Curtis, Carol D. Moffett
Associations Of Polygenic Risk Scores For Type 2 Diabetes With Metabolic Measures In Pacific Islanders From Guam And Saipan, Maria J. Ramirez-Luzuriaga, Saied Safabakhsh, Rasol Salehi, Sayuko Kobes, Tanisha F. Aflague, Jenny Duenas Sarmiento, Joanne Curran, Robert G. Nelson, Jeffrey M. Curtis, Carol D. Moffett
Human Genetics Publications
Several polygenic risk scores (PRSs) for type 2 diabetes (T2D) have been derived from genome-wide association studies (GWASs), but Pacific populations have generally not been represented in these GWASs. The aim of this study was to examine the association of PRS for T2D with diabetes and clinical measures in Pacific Islander populations from Guam and Saipan. We analyzed seven constructions of PRSs in 1990 participants in a GWAS from a community-based cross-sectional study of diabetes. Associations of T2D PRS with diabetes, maximum body mass index (BMI), fasting glucose, and HbA1c were examined with adjustment for age, sex, and the first …
Visual Cues Attract Adult Tunga Penetrans (Siphonaptera: Tungidae), Ayako Hyuga, Paul Ouma, Lynne Elson, Kazuchiyo Miyamichi, Satoshi Kaneko, Kensuke Goto, Tullu Bukhari, Jürgen Krücken, Ulrike Fillinger
Visual Cues Attract Adult Tunga Penetrans (Siphonaptera: Tungidae), Ayako Hyuga, Paul Ouma, Lynne Elson, Kazuchiyo Miyamichi, Satoshi Kaneko, Kensuke Goto, Tullu Bukhari, Jürgen Krücken, Ulrike Fillinger
All Peer-Reviewed Publications
Tunga penetrans (Linnaeus, 1758) (Siphonaptera: Tungidae) is an ectoparasitic flea whose adult females cause tungiasis by embedding into the host’s skin. Environmental, social and financial challenges in tungiasis endemic areas have left this disease neglected and lacking locally available control measures. One possible approach for controlling T. penetrans targets its off-host stages; however, surveillance tools for adult fleas are still lacking. Moreover, host-seeking cues and behaviour of adult T. penetrans remain largely unknown. In this study, we show that visual cues are attractive to adult T. penetrans. Newly emerged T.penetrans responded to light stimuli across a broad spectrum, ranging from …
Machine Learning In Flow Cytometry For Acute Myeloid Leukemia Diagnosis: A Scoping Review, Katrina Jezzela M. Dela Pena Md, Mls (Ascp)
Machine Learning In Flow Cytometry For Acute Myeloid Leukemia Diagnosis: A Scoping Review, Katrina Jezzela M. Dela Pena Md, Mls (Ascp)
Other Specialties
Manuscript version:
Introduction: Flow cytometry is essential for the diagnosis of acute myeloid leukemia (AML), but conventional analysis is labor-intensive, operator-dependent, and increasingly complex. Machine learning (ML) may support automated analysis; however, its readiness for clinical implementation remains unclear. This scoping review mapped ML approaches applied to flow cytometry for AML-related diagnosis.
Methods: PubMed was searched for English-language primary studies applying artificial intelligence, ML, or deep learning to human flow cytometry data for AML diagnosis or classification. Eligible studies reported diagnostic performance metrics. Study characteristics, preprocessing, data representation, model architecture, validation strategy, performance metrics, interpretability, and implementation considerations were descriptively …
Temporal Dynamics Of Sensorimotor Integration For Auditory And Proprioceptive Target Information During Movement Preparation And Execution, Ivan Camponogara
Temporal Dynamics Of Sensorimotor Integration For Auditory And Proprioceptive Target Information During Movement Preparation And Execution, Ivan Camponogara
All Works
Actions toward non-visual targets exhibit modality-specific patterns of endpoint variability, with movements toward auditory targets being more variable than those toward proprioceptive or multisensory targets. However, whether such modality-specific effects emerge already during movement preparation and how they evolve across movement execution remains unclear. The present study addressed this question by asking participants to perform reaching movements toward auditory, proprioceptive, or audio-proprioceptive targets while electromyography and movement kinematics were recorded. Movement preparation and initiation was assessed by analyzing two temporal components of reaction time, premotor and motor, together with movement kinematics at peak acceleration. Movement execution was investigated by analyzing …
Membrane Progestin Receptors Α And Β (Paqr7 And 8) Are Necessary For Oogenesis In Zebrafish, Md. Almamun Farid, Md. Razain Tanvir, Takumi Mouri, Eisei Tsutsumi, Md. Sohanur Rahman Sohan, Md. Ekramul Hasan, Md Saydur Rahman, Chihiro Yamamoto, Akiteru Maeno, Toshinobu Tokumoto
Membrane Progestin Receptors Α And Β (Paqr7 And 8) Are Necessary For Oogenesis In Zebrafish, Md. Almamun Farid, Md. Razain Tanvir, Takumi Mouri, Eisei Tsutsumi, Md. Sohanur Rahman Sohan, Md. Ekramul Hasan, Md Saydur Rahman, Chihiro Yamamoto, Akiteru Maeno, Toshinobu Tokumoto
School of Integrative Biological & Chemical Sciences Faculty Publications
Paqr7 and paqr8 are genes encoding membrane progestin receptor αand β (mPRα and mPRβ, respectively), which are currently classified as members of the progestin and adipoQ receptor (PAQR) family. For mPRα, the first identified mPR gene, there are two paralogs in zebrafish, paqr7a and paqr7b. In order to elucidate the physiological functions of the mPR subtypes, we created gene knockout (KO) fish by editing seven paqr genes in zebrafish and analyzing their phenotypes. The null-mutant strains of paqr7a, paqr7b, and paqr8 presented no significant abnormalities in reproductive functions. Thus, we generated a triple-gene knockout (TKO) strain of …
Molecular Refinement Of The Taxonomy Of Pyrgulopsis Springsnails In Western North America, Michael K. Young, Kristine L. Pilgrim, Eric S. Miskow, Chante L. Lundskog, Kathryn E. Perez, Michael K. Schwartz
Molecular Refinement Of The Taxonomy Of Pyrgulopsis Springsnails In Western North America, Michael K. Young, Kristine L. Pilgrim, Eric S. Miskow, Chante L. Lundskog, Kathryn E. Perez, Michael K. Schwartz
School of Integrative Biological & Chemical Sciences Faculty Publications
Springsnails in the genus Pyrgulopsis in western North America have long been a dilemma for taxonomists. Defining species boundaries has been complicated by the presence of undiscovered or cryptic taxa, range over- or underestimation, species complexes representing an unknown number of species, and named species synonymous with other taxa. To address these issues, we conducted an array of molecular species delimitation analyses using sequences from up to 2 mitochondrial and 2 nuclear genes from over 5000 specimens representing 140 of the 151 currently recognized taxa. These analyses reaffirmed most species hypotheses, favored synonymy for some taxa and redrawing of species …
Harnessing Kenyan Aquaculture Through Social Media: Impacts, Challenges And Strategic Directions, Domitila Kyule, Jonathan Munguti, Mavindu Muthoka, Esther Magondu, Menaga Meenakshisundaram, Chrysantus M. Tanga, Kevin Obiero, Cecilia Githukia
Harnessing Kenyan Aquaculture Through Social Media: Impacts, Challenges And Strategic Directions, Domitila Kyule, Jonathan Munguti, Mavindu Muthoka, Esther Magondu, Menaga Meenakshisundaram, Chrysantus M. Tanga, Kevin Obiero, Cecilia Githukia
All Peer-Reviewed Publications
Aquaculture is increasingly important for food, nutrition and livelihoods in Kenya, but the sector still faces persistent constraints in extension delivery, farmer learning, input access, market coordination and information reliability. This review examines how social media and related digital communication tools are shaping aquaculture development in Kenya, with attention to impacts, challenges, governance needs and strategic directions. A systematic literature review of studies and institutional sources published between 2015 and 2025 was conducted. The search identified 388 records, of which 45 sources were included in the final synthesis after screening, eligibility assessment and quality appraisal. Because the evidence was heterogeneous, …
Tissue-Specific And Sex-Dependent Microbiome Structure In East African Cattle Ticks (Amblyomma Gemma And Rhipicephalus Pulchellus) And Their Bovine Hosts, Dennis Getange, Samson Mukaratirwa, Rua Khogali, Epaphrus Yuko, James Kabii, Joel L. Bargul, Jandouwe Villinger
Tissue-Specific And Sex-Dependent Microbiome Structure In East African Cattle Ticks (Amblyomma Gemma And Rhipicephalus Pulchellus) And Their Bovine Hosts, Dennis Getange, Samson Mukaratirwa, Rua Khogali, Epaphrus Yuko, James Kabii, Joel L. Bargul, Jandouwe Villinger
All Peer-Reviewed Publications
Ticks and their vertebrate hosts share intimate ecological interactions that shape microbial community composition, with implications for tick fitness and pathogen transmission. However, the extent and specificity of tick–host microbial interactions remain poorly understood, particularly in East African tick species. Here, we characterised microbial communities across multiple tissue types from two economically important tick species (Amblyomma gemma and Rhipicephalus pulchellus) and their shared bovine host using 16S rRNA V1-V2 gene sequencing. We profiled haemolymph, midgut, salivary glands, and gonads from individual ticks (25 Am. gemma and 8 Rh. pulchellus), alongside 12 bovine blood samples. Microbiota were dominated by Proteobacteria, Firmicutes, …
Performance Of The Denitrification-Decomposition Model In Simulating Agronomic Properties And N2o Emissions Under Smallholder Climate-Smart Farming Systems, Esphorn Kibet, Collins M. Musafiri, Milka Kiboi, Onesmus K. Ng'etich, David K. Kosgei, Abdirahman Zeila, Franklin Mairura, Felix K. Ngetich
Performance Of The Denitrification-Decomposition Model In Simulating Agronomic Properties And N2o Emissions Under Smallholder Climate-Smart Farming Systems, Esphorn Kibet, Collins M. Musafiri, Milka Kiboi, Onesmus K. Ng'etich, David K. Kosgei, Abdirahman Zeila, Franklin Mairura, Felix K. Ngetich
All Peer-Reviewed Publications
The DeNitrification-DeComposition (DNDC) model is a crucial tool for estimating soil greenhouse gas fluxes and understanding soil-plant interactions. This study evaluates the performance of the DNDC model in simulating soil temperature, moisture, crop yield, and nitrous oxide (N2O) fluxes across different land utilization types in Western Kenya. The land utilization types included: i) agroforestry M (agroforestry with Markhamia lutea, ii) sole sorghum, iii) agroforestry L (agroforestry with Leucaena leucocephala), iv) sole maize, and v) grazing Land, each replicated thrice. Fertilizer and manure were applied as part of the management practices, with manure applied at 2t ha−1. Soil greenhouse …
The Influence Of Ecological Pest Management Practices On Pests And Natural Enemies Under A Cabbage–Garden Pea Rotational System In Central Kenya, Peter Nyakundi Mageto, Milka Kiboi, Monicah Mucheru-Muna, Felix Matheri
The Influence Of Ecological Pest Management Practices On Pests And Natural Enemies Under A Cabbage–Garden Pea Rotational System In Central Kenya, Peter Nyakundi Mageto, Milka Kiboi, Monicah Mucheru-Muna, Felix Matheri
All Peer-Reviewed Publications
Pest pressure is a major constraint on crop production in Sub-Saharan Africa, where smallholder farmers rely heavily on synthetic pesticides with potential environmental and health risks. Ecological pest management practices (EPMs) have been proposed as sustainable alternatives, although field-based evidence is limited. This study evaluated pest and natural-enemy responses to EPMs in a cabbage–garden pea rotation system over six years (2020–2025) in Central Kenya. Four treatments were assessed: homemade botanical extracts (Botanicals), coriander intercropping (Intercrop), botanical extracts combined with coriander intercropping (Botanicals + Intercrop), and a control. In cabbage, ecological treatments often recorded lower aphid and diamondback moth abundance and …