Life Sciences Commons^™

Modeling Als-Associated Matrin-3 Toxicity In Yeast, Widad El-Zein

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ALS is a neurodegenerative disease characterized by degeneration of upper and lower motor neurons in the brain and spinal cord leading to progressive paralysis and ultimately death. Perturbations in RNA metabolism and RNA binding proteins have emerged as underlying defects in ALS pathogenesis. Matrin-3 is a multifunctional RNA binding protein that has been linked to familial and sporadic ALS. Matrin-3 is normally found in the nucleus, but mutations in the gene cause mislocalization of the protein from the nucleus into the cytoplasm of neuronal cells where it forms protein aggregates. In this study, we show that over-expressing human MATR3 in …

The Role Of Pi4kb In Cellular Localization Of Small Gtpases, Parisa Sadrpour

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Constitutively active oncogenic mutant K-Ras is one the principal contributors to human cancers including 90% of pancreatic, 50% of colorectal and 32% of non-small cell lung cancers. However, except for K-Ras G12C oncogenic mutant, which only presents in about 13% of non-small cell lung cancer patients, there is no anti-K-Ras therapy for a considerable subset of K-Ras mutations in human tumors, reflecting challenges for targeting oncogenic K-Ras activity. K-Ras is a membrane-bound small GTPase; when active, it triggers multiple signaling pathways regulating a variety of key cellular functions such as cell growth, proliferation and survival. To initiate these signaling cascades, …

Reconstruction Of Gut Microbiome Via Intermittent Feeding, Kourtney Sprague

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The benefits of intermittent fasting have been studied across many facets of health. It is known that physiologically fasting results in a metabolic switch from liver-derived glucose to adipose cell derived ketones to be used as energy and signaling molecules. Fasting down-regulates inflammation, increases expression of antioxidant defenses, and activates pathways for DNA repair and autophagy. While fasting or intermittent feeding effects on host physiology have been identified, the relationship between fasting and gut microbiome is not as well known. In times of gut rest, resident microbes undergo detoxication and motility, and in times of activity, gut microbes undergo DNA …

Valorisation Of The Effects Of Bioactive Compounds Of The Ethanolic Extract Of Ramalina Farinacea (Ramalinaceae) On The Development, Eating And Pupation Behavior Of Drosophila Melanogaster (Diptera: Drosophilidae), Fatma Zohra Saadane, Nour El Imene Boublata, Sarra Habbachi, Abir Bouzar, Waffa Habbachi, Abderachid Slimani, Abdelkrim Tahraoui

Journal of Bioresource Management

Plants are rich in bioactive chemical secondary metabolites and have proven insecticidal activity by killing or repelling insects. In this work, we aim to evaluate the direct and delayed effects of ethanolic plant extracts on the vinegar fly (Drosophila melanogaster). The treatment was performed by ingestion on second instar larvae (L2) to evaluate the impact of the ethanolic extract on development for 15 days and subsequently on the feeding behavior of the larvae. The results of this study indicate a slowing down of pupal growth until the adult stage, at the three concentrations (0.25 µg/ml, 0.5 µg/ml, 1.5 …

Biodiversity Of The Blattopteran Fauna In The Chelia Cedar Forest (The Aures - Eastern Algeria), Nadia Aberkane, Sarra Habbachi, Wafa Habbachi, Nora Belkhiri, Naama Frah

Journal of Bioresource Management

The cedar forests in Algeria represent a model of forests very rich in entomological fauna and especially dictyopterans, notably blattopterans. In the cedar forest of Chelia in the Aurès Mountains, we chose three different sites according to altitude (2020 m, 1920 m, 1820 m) in order to collect existing cockroaches using the sight-hunting method (twice a month). The inventory allowed us to capture more than 1220 cockroaches and we were able to identify three genus (Dziriblatta, Phyllodromica ,Loboptera) and seven species: Dziriblatta stenoptera, Dziriblatta nigrivintris, Phyllodromica zebra, Pyllodromica trivittata, Phyllodromica sp, Loboptera angulata, Loboptera alluaudi, of which …

Structure And Parasitism Of Egg-Batches Of The Pine Processionary Moth, Thaumetopoea Pityocampa In The Algerian Cedar Forests., Zineb Messaadia, Nabil Bertella, Naama Frah

Journal of Bioresource Management

Today, climate change is one of the greatest threats facing forest ecosystems. It directly influences the geographical distribution of insects and increases epidemics of harmful insects. The present work took place in this context. It aimed to contribute to the knowledge of egg parasitoids that could affect the evolution of the pine processionary caterpillar Thaumetopoea pityocampa, a major forest pest in Algeria and Mediterranean countries. The study was carried out on 120 batches of eggs taken from the Atlas cedar at two sites in the Chelia cedar zone (case of eastern Algeria) in 2017. It allowed the analysis of a …

Composition, Population Structure And Regeneration Potential Of Tree Species In Oak-Dominated Mixed Forests Of Rajouri District In Jammu And Kashmir, India, Mohd Junaid Jazib, Javed Manzoor

Journal of Bioresource Management

The study was carried out to explore the diversity and regeneration potential of trees species in mixed Oak forest of Rajouri district of Jammu and Kashmir (India). A total of 20 tree species were recorded from the area dominated by various species of oak particularly Quercus leuchotrichophora. Quercus leuchotrichophora shows maximum values of density, basal cover and IVI. In different localities, it has different groups of associates like Q. floribunda, Q. semecarpifolia, Q. glauca, Buxux wallichiana, Pinus roxburghii, Aesculus indica, Rhododendron arboreum, etc. Majority of the species show very poor regeneration and thus demands for immediate implementation of appropriate conservation …

Evaluation Of The Toxic Effects Of Aqueous Extracts Of Solanum Nigrum L.( Solanaceae ) On The Mortality And Development Of Drosophila Melanogaster (Diptera : Drosophilidae)., Makarem Rahat, Sara Habbachi, Ibtissem Samai, Wafa Habbachi, Abir Bouzar, Saliha Benhissen, Abdelkrim Tahraoui

Journal of Bioresource Management

Solanum nigrum is a plant that has therapeutic properties of the Solanaceae family. It is used extensively in traditional medicine but also as a bio-insecticide to control insect pests. Some parts of this plant can be very toxic to livestock and humans. In the present study, the direct and delayed toxic effects of aqueous extracts of S. nigrum on the mortality and development of Drosophila melanogaster were investigated. For this study, an extraction method including decoction is adopted to extract the active principles from the leaves of S. nigrum. The treatment was carried out by ingestion on 2nd instar …

Measuring Science Teachers' Emotional Experiences With Evolution Using Real World Scenarios, William Lee Romine, Rutuja Mahajan, Amber Todd

Biological Sciences Faculty Publications

Low acceptance of evolution remains an obstacle to quality biology instruction. We develop and utilize a novel assessment which measures emotional experience in light of real-world evolution education scenarios. We presented 296 science teachers 4 pro-evolution and 8 anti-evolution scenarios and asked them to rate their levels of joy, anger, sadness, fear, disgust, shame, and guilt elicited by that scenario on an ordinal 5-point scale. We used exploratory factor analysis to extract the most important dimensions in the teachers’ responses, Rasch analysis to explore the validity of the extracted subscales, and stepwise regression to find the most important factors driving …

Sensor-Based Prediction Of Mental Effort During Learning From Physiological Data: A Longitudinal Case Study, Ankita Agarwal, Josephine Graft, Noah Schroeder, William Romine

Biological Sciences Faculty Publications

Trackers for activity and physical fitness have become ubiquitous. Although recent work has demonstrated significant relationships between mental effort and physiological data such as skin temperature, heart rate, and electrodermal activity, we have yet to demonstrate their efficacy for the forecasting of mental effort such that a useful mental effort tracker can be developed. Given prior difficulty in extracting relationships between mental effort and physiological responses that are repeatable across individuals, we make the case that fusing self-report measures with physiological data within an internet or smartphone application may provide an effective method for training a useful mental effort tracking …

Plastic Biodegradation Through Insects And Their Symbionts Microbes: A Review, Huda Bilal, Hasnain Raza, Haseena Bibi, Tehmina Bibi

Journal of Bioresource Management

Plastic waste has recently been identified as one of the most serious environmental issues, affecting all life forms, natural habitats, and the economy, and is one of the most serious global environmental problems, second only to climate change. Seeking alternative environmentally sustainable options, such as biodegradation instead of conventional disposal, is critical in the face of this challenge. However, there is currently a lack of information about the mechanisms and efficacy of plastic biodegradation. From this perspective, this study aims to illustrate the negative environmental impacts of the plastic waste. It also addresses the role of insects and gut microbiota …

Salinity Stress Mitigation By Foliar Feeding Of Salicylic Acid On Maize (Zea Mays L.) Grown Under Hydroponic Culture, Zubair Aslam, Ali Ahmad, Anser Ali, Alam Sher, Muhammad Sarwar

Journal of Bioresource Management

Salicylic acid (SA) is mainly associated with the regulation of plant growth particularly in salinity stress conditions and this signaling molecule exists in pivotal parts of plant. The objective of this research analysis was to overcome stress condition by distinct foliar treatments of Salicylic acid, for instance, 0 and 100 mM. Foliar applications of SA on maize were rendered on 10 days later than transplanting under a hydroponics experiment. Plants were grown under non-saline (S₀= 0 mM NaCl) and saline (S₁= 100 mM NaCl) conditions. Evaluation of biochemical, physiological and morphological attributes of maize was rendered …

Factors Affecting The Epizootics Of Entomopathogenic Fungi-A Review, Mirza Abdul Qayyum, Huda Bilal, Unsar Naeem Ullah:, Habib Ali, Hasnain Raza, Muhammad Wajid

Journal of Bioresource Management

Entomopathogenic fungi (EPF) specifically infect and kill insects can serve as a potential biological control agent. Several biotic and abiotic factors affect their occurrence, persistence, and epizootics caused by them. In biotic factors, fungi characters (host range, latency, spore density and dispersal, mainly host-pathogen compatibility), insect host factors (behavioral, morphological, and physiological), plant-mediated effects (plant architecture, surface chemistry, and leaf topology) are included supports or causes the barrier to mycobiopesticide. Abiotic factors which affect the EPF field persistence are mainly environmental (temperature, sunlight, humidity, rainfall) physical and chemical soil properties (soil texture, pH, E.c, moisture, C/N content, and organic matter) …

Estimation Of Genetic Diversity Among Canola Accessions Using Simple Sequence Repeat Markers, Jaleel Ahmad, Muhammad Baber, Wajid Nazeer, Sana Hamdullah, Aleena Ahmad Somroo, Shaiza Ali, Rameen Fatima, Seema Aslam

Journal of Bioresource Management

Genetic studies through molecular markers proved important to find out the genetic diversity of canola. In this study, 50 lines of canola were used to find the polymorphism using 15 SSR primers and investigated the genetic diversity, PIC values, frequency-based genetic distance, and allelic frequencies. Mean gene diversity, frequency-based genetic distance, and PIC values were 0.8777, 0.233 and 0.8666, respectively for the canola lines. A good range of genetic diversity was found among studied canola lines with value 85.91% polymorphism. Maximum and minimum genetic distances among 50 lines were 1 and 0.26, respectively. Accessions ACC-26068, ACC-24241, ACC-24244, ACC-24233, ACC-24423 and …

Prevalence And Multidrug Resistance Pattern Of E. Coli Among Urinary Tract Infection Patients In Tertiary Care Hospital Of Multan, Hubza Ruatt Khan, Mehvish Javeed, Asghar Javed, Nisma Farooq

Journal of Bioresource Management

Urinary Tract Infection is alarming problem worldwide due to the intensity of antimicrobial resistance. Escherichia coli is the most predominant organism in UTI. This study was planned to evaluate demographic parameters, the prevalence of E. coli, and antimicrobial resistance patterns among E. coli isolates from UTI patients in Nishtar Hospital of Multan from January to June 2018. A total of 350 mid-stream urine samples were collected from different patients having age group from 25 to 60 years and processed by standard laboratory procedures. Out of 350 samples, 100 samples were observed as critical bacteremia. Escherichia coli and Klebsiella …

Undesired Effects Of Bioinsecticides Molecules In Wistar Rats: Case Of Spirotetramat, Citrulus Colocynthis And Cleome Arabica Extracts, Boublata Nour El Iméne, Manel Bekhakheche, Habbachi Sarra, Saadane Fatma Zohra, Bouzar Abir, Habbachi Wafa, Rebbas Khellaf, Tahraoui Abedkrim

Journal of Bioresource Management

The use of pesticides is becoming an indispensable technique in most agricultural practices, regardless of the level of development of the country. Currently, the pesticides used are often less toxic and more specific and are based on insect physiology. Recent studies indicate that pesticide intoxication induces oxidative stress. This work aims to study the neurobehavioral consequences of the administration of two insecticides currently widely used in agriculture: spirotetramat (an inhibitor of lipid synthesis in insects) and the ethanolic extract of Citrullus colocynthis (a plant endemic to the Algerian Sahara) and the ethanolic extract of Cleome arabica (Capparidaceae) The …

Inventory And Distribution Of Mosquitoes (Diptera, Culicidae) In The Aures Region (Batna, Algeria), Nora Belkhiri, Wafa Habbachi, Saliha Benhissen, Naama Frah, Abdelmadjid Yagoub Asloum, Nadia Aberkane

Journal of Bioresource Management

Mosquitoes are the most terrifying both for their abundance and for the diseases they transmit. They are vectors of malaria, lymphatic filariasis and arbovirus such as yellow fever, dengue, viral encephalitis and African horse sickness. These characteristics give this fauna prominent importance and health interest. To identify the most widespread mosquito species, we conducted for the first time an inventory in the Aures region more particularly the wilaya of Batna (East of Algeria) from May 2017 to January 2020, we studied their diversity, abundance and distribution. The sampling is done by monthly surveys of the various localities chosen, using the …

Climate Change Is Driving Greening Trend Whereas Tree Cover Is Declining In The Western Himalaya Of Pakistan, Arshad Mahmood Khan, Nadia Khalid

Journal of Bioresource Management

Recent studies suggest that two factors including climate change (especially precipitation) and human land use management (HLUM) are primarily driving greening trend around the world. However, studies targeting the impact of both factors on different vegetation layers (i.e. herbs, shrubs and tree layers) are lacking. This study hypothesize that precipitation relatively influence the under-storey vegetation cover more quickly, and HLUM (say afforestation/reforestation, deforestation) is more important towards top-storey layer. To investigate this, 13 randomly selected permanent stations in the wild natural west Himalayan coniferous forests of Sudhan Gali, Pakistan were explored from 2000-2016 to collect vegetation health data by two …

Preliminary Checklist Of Avifauna Of Tamanrasset (South Of Algeria) With Two New Records In Algeria, Belkacem Aimene Boulaouad, Ailam Oussama, Telailia Salah, Harzallah Mourad, Ayyach Khaled, Bekkouche Abdelkadir Missoum Mohamed, Soukkou Walid, Boutabia Lamia

Journal of Bioresource Management

Birds constitute a zoological group which is considered to be a good indicator of balance and biological diversity. The aim of this study was to investigate the birds of the region on Tamanresset which is situated in the south of Algeria and has an area of 554.000 km². Direct observations with camera and a pair of binoculars, supported by ornithological surveys carried out by progressive frequently sampling, in each stations of study area, 44 bird species were observed in this region which fall into 12 orders and 24 families. Among these species, 3 new observations recorded for the …

Effects Of Osmotic Stress Induced By Polyethylene Glycol (Peg) 6000 And Mannitol On Seed Germination And Seedling Growth Of Durum Wheat, Ratiba Bousba, Rabah Bounar, Narimene Sedrati, Randa Lakhal, Chourouk Hamla, Malika Rached-Kanouni

Journal of Bioresource Management

Seed germination is generally the critical step in seed establishment and thus the determination of successful crop production. This study was focused at examination of the biochemical and germination parameters effected by low water potential which was generated by polyethylene glycol (PEG) 6000 and mannitol, related to drought stress and growth of Waha durum wheat genotype. Two tests were carried out in a growth chamber; the first comprises seed germination into Petri dishes in the presence of different concentrations of the two osmoticums (0, 5, 10, 15 and 20 % of PEG6000 and mannitol). The second test was carried out …

Preliminary Inventory And General Aspect Of The Distribution Of Culicidae Species In The Steppe Region (M'Sila, Algeria), Abdelmadjid Yagoub Asloum, Saliha Benhissen, Wafa Habbachi, Sarra Habbachi, Zakaria Hedjouli, Zihad Bouselama, Abdelkrim Tahraoui

Journal of Bioresource Management

Mosquitoes are important living organisms that participate in the different levels of food chains. However, many families include vector species capable to transmit viruses, bacteria and parasites to both humans and animals, threatening the public health. The goal of this work was to describe the biological diversity of mosquito species in different areas in M'sila; Algeria based on the ecological nature of their habitat. The breeding sites found were 18 distributed in five areas (Berhoum, Bou Saâda, El hamel, Hammam Dhalaa and M'sila). The inventory that was carried out from September to April every year from 2017 to 2019 has …

Abundance And Distribution Of The Forest Cockroaches In Different Algerian Ecosystems, Zakaria Hedjouli, Wafa Habbachi, Fatiha Masna, Saliha Benhissen, Sarra Habbachi, Abdelmadjid Yagoub Asloum, Abdelkrim Tahraoui

Journal of Bioresource Management

Forests have many insect species that are unique to biodiversity and play a crucial role in the functioning of ecosystems. Forest cockroaches are the best example of forest litter insects, which also help decompose fallen leaves. The composition of the Blattoptera fauna can vary from one region to another, depending on the habitat and numerous biotic and abiotic factors In order to study the diversity, abundance, and distribution of forest cockroaches in different Algeria ecosystems, we have selected four sites from three Wilayas: Senalba (Djelfa), Ain achir (Annaba), Seraidi (Annaba), and Lehnaya (El-taref). These sites are classified into two distinct …

Enhancing The Fertilizer Value Of Cattle Manure Using Organic Resources For Soil Fertility Improvement: A Review, Benedicta E. Ayamba, Robert C. Abaidoo, Andrews Opoku, Nana Ewusi-Mensah

Journal of Bioresource Management

The poor quality of cow dung in Ghana resulting from the opportunistic feeding mode of cattle impedes its adoption due to high quantities needed for application. This calls for nutrient optimization of cattle manure with inexpensive locally available sources of organic inputs that could enhance its quality. Though large volumes of crop residues and other agro-wastes are produced on-farm, they are underutilized and mostly a nuisance. Major food crops take approximately, 44 %, 42 % and 56 % of the total nitrogen (N), phosphorus (P) and potassium (K), respectively and are found in crop residues. There is therefore the need …

Virtual Interviews In The Era Of Covid-19: Expectations And Perceptions Of Orthopaedic Surgery Residency Candidates And Program Directors, David A. Brueggeman, Garrhett G. Via, Andrew W. Froehle, Anil Krishnamurthy

School of Health and Exercise Sciences Faculty Publications

Orthopaedic surgery residency program directors (PDs) and candidates consider interviews to be central to the application process. In-person interviews are typical, but virtual interviews present a potentially appealing alternative. Candidate and PD expectations and perceptions of virtual interviews during the 2020/2021 orthopaedic surgery application cycle were assessed.

Methods: Candidates and PDs were surveyed electronically. Questions covered pre-virtual-interview and post-virtual-interview expectations and perceptions, and past in-person experiences (PDs and reapplicants) on the relative importance of application components, ability to assess fit, interview costs, and preferred interview mode. Identical questions allowed between-group comparisons.

Results: Responses included n = 29 PDs and n …

Craniometric Analysis Of European Rabbit (Oryctolagus Cuniculus) Breeds To Trace Out Intraspecific And Inter Gender Morphometric Variations, Muhammad Rizwan, Rana Manzoor Ahmad, Abdul Majid Khan, Misbah Khalid, Muhammad Wajid

Journal of Bioresource Management

The family Liproidae expresses the significant variation of morphometric features at species level. In already available literature on the European rabbit (Oryctolagus cuniculus) the idea is proposed that there can be variation in the morphometric character of different breeds of Oryctolagus cuniculus but there are negligible scientific research base evidences for it. So in this study interbreed craniometric comparison of the European rabbit is carried out to trace out their intergender and intraspecific morphometric variations. The study material consists of 32 sexually mature rabbits belong to two breeds of European rabbit that are New Zealand rabbit (eight males and …

Cryptic Constituents: The Paradox Of High Flux–Low Concentration Components Of Aquatic Ecosystems, Malin Olofsson, Mary E. Power, David A. Stahl, Yvonne Vadeboncoeur, Michael T. Brett

Biological Sciences Faculty Publications

The interface between terrestrial ecosystems and inland waters is an important link in the global carbon cycle. However, the extent to which allochthonous organic matter entering freshwater systems plays a major role in microbial and higher-trophic-level processes is under debate. Human perturbations can alter fluxes of terrestrial carbon to aquatic environments in complex ways. The biomass and production of aquatic microbes are traditionally thought to be resource limited via stoichiometric constraints such as nutrient ratios or the carbon standing stock at a given timepoint. Low concentrations of a particular constituent, however, can be strong evidence of its importance in food …

A Review Of Novel Coronavirus: Cross-Disciplinal Perspective, Iram Asim, Hafsa Rehman, Rabeea Anwar, Humaira Yasmeen

Journal of Bioresource Management

The whole world is under the influence of coronavirus after its first report from Wuhan, China in December 2019. The virus is from coronaviridae family which has zoonotic viruses that can spread from animals to humans. The coronavirus like other viruses of this family produces mild flu-like symptoms within 2-14 days in the human host which progresses to death in severe cases. Unlikely coronavirus spread fast among humans-infectious diseases. Up till now (27/04/2020) around 2.97M cases and 207K deaths have been reported. The presence of a virus in respiratory secretions is diagnosed through molecular methods and chest scans. For this …

Quantifing Diversity And Phenology Of Cereal Leaf Beetles Oulema Spp. (Chrysomelidae: Criocerinae) In Several Cereal Fields Of Semi-Arid Zone, Algeria, Chirine Amri

Journal of Bioresource Management

The present study treated the taxonomic diversity of the cereal leaf beetle (Oulema spp.) community subservient to several cereal fields (barley, durum wheat and oats) in Eastern Algeria. From April to June, which is the appearance period of these insects, the leaf beetle fauna was weekly sampled using two trapping techniques: entomological net and sight hunting method. Spatiotemporal alpha and beta diversity of this community were evaluated by several ecological indices: Shannon index, Simpson index and equitability. The multivariate statistic test (GLM) was used to assess the variation of the different diversity parameters. Catches totaled 1144 individuals belonging …

Correlation, Regression Analysis Of Seed Oil Contents In Relation To Morphological Characters In Cotton, Hafiz Muhammad Awais, Sarmad Frogh Arshad, Wajad Nazeer, Muhammad Usman, Abdul Latif Khan Tipu, Muqarrab Ali, Asif Saleem, Hasan Junaid Arshad, Asma Shah Rukh

Journal of Bioresource Management

Cotton is the backbone of Pakistan’s economy. More than half of the export of Pakistan depends on cotton and cotton-based products. Morphological quantitative traits are important for estimation of cotton yield. In this regard, a study was conducted to evaluate the morphological responses on cotton crop at experimental farm of MNS-University of Agricultural Multan during the year 2019-2020. Four cotton varieties with different time windows (early, normal and late) were sown in a randomized complete block design (RCBD) in a split plot arrangement. Correlation and regression studies of cultivars of Gossypium and Malvaceae were analyzed for quantitative characters. Result revealed …

Depth-Discrete Metagenomics Reveals The Roles Of Microbes In Biogeochemical Cycling In The Tropical Freshwater Lake Tanganyika, Patricia Q. Tran, Samantha C. Bachand, Peter B. Mcintyre, Benjamin M. Kraemer, Yvonne Vadeboncoeur, Ismael A. Kimirei, Rashid Tamatamah, Katherine D. Mcmahon, Karthik Anantharaman

Biological Sciences Faculty Publications

Lake Tanganyika (LT) is the largest tropical freshwater lake, and the largest body of anoxic freshwater on Earth's surface. LT's mixed oxygenated surface waters float atop a permanently anoxic layer and host rich animal biodiversity. However, little is known about microorganisms inhabiting LT's 1470 meter deep water column and their contributions to nutrient cycling, which affect ecosystem-level function and productivity. Here, we applied genome-resolved metagenomics and environmental analyses to link specific taxa to key biogeochemical processes across a vertical depth gradient in LT. We reconstructed 523 unique metagenome-assembled genomes (MAGs) from 34 bacterial and archaeal phyla, including many rarely observed …