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Wright State University

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Articles 1981 - 1987 of 1987

Full-Text Articles in Life Sciences

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers Nov 1989

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The location of the translational termination codon for the transmembrane protein (TMP) varies in three infectious molecular clones of simian immunodeficiency virus from macaques (SIVmac). The SIVmac251 and SIVmac142 infectious clones have premature stop signals that differ in location by one codon; transfection of these DNAs into human HUT-78 cells yielded virus with a truncated TMP (28 to 30 kilodaltons [kDa]). The SIVmac239 infectious clone does not have a premature stop codon in its TMP-coding region. Transfection of HUT-78 cells with this clone initially yielded virus with a full-length TMP (41 kDa). …

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Micronuclear Genome Organization In Euplotes Crassus: A Transposonlike Element Is Removed During Macronuclear Development, Scott Everet Baird, Gina M. Fino, Susan L. Tausta, Lawrence A. Klobutcher Sep 1989

Micronuclear Genome Organization In Euplotes Crassus: A Transposonlike Element Is Removed During Macronuclear Development, Scott Everet Baird, Gina M. Fino, Susan L. Tausta, Lawrence A. Klobutcher

Biological Sciences Faculty Publications

After mating, hypotrichous ciliated protozoa transform a set of their micronuclear chromosomes into thousands of short, linear DNA molecules that form the macronuclear genome. To examine micronuclear genome organization in the hypotrich Euplotes crassus, we have analyzed two cloned segments of micronuclear DNA as well as the macronuclear DNA molecules that are derived from them. E. crassus was found to display a number of features characteristic of other hypotrich genomes, including (i) clustering and close spacing of the precursors of macronuclear DNA molecules, (ii) the frequent occurrence of internal eliminated sequences within macronuclear precursors, (iii) overlapping macronuclear precursors, (iv) lack …

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Fault Tolerance In A Very Large Database System: A Strawman Analysis, Amit P. Sheth Jun 1989

Fault Tolerance In A Very Large Database System: A Strawman Analysis, Amit P. Sheth

Kno.e.sis Publications

A simple model is used to study the effect of fault-tolerance techniques and system design on system availability. A generic multiprocessor architecture is used that can be configured in different ways to study the effect of system architectures. Important parameters studied are different system architectures and hardware fault-tolerance techniques, mean time to failure of basic components, database size and distribution, interconnect capacity, etc. Quantitative analysis compares the relative effect of different parameter values. Results show that the effect of different parameter values on system availability can be very significant. System architecture, use of hardware fault tolerance (particularly mirroring), and data …

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Characterization Of Chromosome Fragmentation In Two Protozoans And Identification Of A Candidate Fragmentation Sequence In Euplotes Crassus, Scott Everet Baird, Lawrence A. Klobutcher Jan 1989

Characterization Of Chromosome Fragmentation In Two Protozoans And Identification Of A Candidate Fragmentation Sequence In Euplotes Crassus, Scott Everet Baird, Lawrence A. Klobutcher

Biological Sciences Faculty Publications

Following the sexual cycle, hypotrichous ciliated protozoans fragment a set of their micronuclear chromosomes to generate the thousands of short, linear DNA molecules present in the transcriptionally active macronucleus. We have used a hybrid selection procedure to examine macronuclear DNA molecules for subtelomeric length heterogeneity to determine whether chromosome fragmentation occurs at unique or multiple sites. The results suggest that multiple, but closely spaced, chromosome fragmentation sites are used by Oxytricha nova. In contrast, Euplotes crassus uses unique chromosome fragmentation sites in a reproducible manner to generate the ends of macronuclear DNA molecules. Additional studies compared DNA sequences in …

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A Tool For Integrating Conceptual Schemas And User Views, Amit P. Sheth, James A. Larson, Aloysius Cornelio, Shamkant B. Navathe Feb 1988

A Tool For Integrating Conceptual Schemas And User Views, Amit P. Sheth, James A. Larson, Aloysius Cornelio, Shamkant B. Navathe

Kno.e.sis Publications

An interactive tool has been developed to assist database designers and administrators (DDA) in integrating schemas. It collects the information required for integration from a DDA, performs essential bookkeeping, and integrates schemas according to the semantics provided. The authors present the capabilities of this tool by discussing the integration methodology and the user interface of the tool.

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An Analysis Of The Effect Of Network Load And Topology On The Performance Of Concurrency Control Algorithm In Distributed Database Systems, Anoop Singhal, Amit P. Sheth, Ming T. Liu Dec 1984

An Analysis Of The Effect Of Network Load And Topology On The Performance Of Concurrency Control Algorithm In Distributed Database Systems, Anoop Singhal, Amit P. Sheth, Ming T. Liu

Kno.e.sis Publications

Earlier studies in the performance analysis of concurrency control algorithms in distributed database systems (DDBS) have assumed that the message transmission time between any two nodes of a network is constant. Hence they disregard the effect of communication subnet related parameters such as network traffic, network topology, the capacity of transmission channels and the size of messages transmitted. In this paper an analytical model is used to estimate the delays in transmission channels for a DDBS in a long haul network. The analysis shows that the constant transmission time assumption cannot be justified in many cases and that response time …

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Botany Sketchbook - Orville Wright, Orville Wright Jan 1887

Botany Sketchbook - Orville Wright, Orville Wright

Wright Family School Items

A botany notebook that belonged to Orville Wright filled with drawings and observations about flowers and other plants sometime between 1887 and 1888.

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