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Melatonin Ameliorates Cisplatin-Induced Neurodegeneration In Medulla Oblongata Through The Expressions Of Aqp-1,-4, Inflammation And Apoptosis Pathway Genes, Rahi̇me Özlem Öztopuz Jan 2022

Melatonin Ameliorates Cisplatin-Induced Neurodegeneration In Medulla Oblongata Through The Expressions Of Aqp-1,-4, Inflammation And Apoptosis Pathway Genes, Rahi̇me Özlem Öztopuz

Turkish Journal of Biology

In this study, the neuroprotective effects of melatonin (MEL) with changes in apoptosis, inflammation, and histopathological morphology were evaluated in the medulla oblongata of cisplatin (CIS) administered rats. Although the side effects of CIS are known in many tissues, its reaction on the medulla oblongata and the molecular association underlying this effect is unclear. Male wistar albino rats were separated into four groups (control, CIS, CIS+MEL, and MEL) (n = 24). CIS and CIS+MEL groups were given 4 mg/kg CIS at 4-day intervals (days 1, 5, 9, and 13) by the first day of the study. The MEL and CIS+MEL …


Bone Marrow Mesenchymal Stem Cells Attenuate Lps-Induced Acute Lung Injury In Mice By Promoting Rve1/Prod1 And Modulating Treg/Th17 Balance, He-Bu Qian, Guijuan Zou, Chao Li, Qifang He, Jun Liu Jan 2022

Bone Marrow Mesenchymal Stem Cells Attenuate Lps-Induced Acute Lung Injury In Mice By Promoting Rve1/Prod1 And Modulating Treg/Th17 Balance, He-Bu Qian, Guijuan Zou, Chao Li, Qifang He, Jun Liu

Turkish Journal of Biology

Acute lung injury (ALI) and its severe form acute respiratory distress syndrome (ARDS) are respiratory failures caused by excessive alveolar inflammation with high mortality. In this study, we investigated the effects of bone marrow mesenchymal stem cells (BMSCs) on lung injury of lipopolysaccharide (LPS)-induced ALI and explored the associated mechanisms. BMSCs were isolated, cultured, identified by staining with CD34 and CD44 surface markers. LPS-induced ALI mouse model was generated by injecting with LPS and divided into ALI group and ALI+BMSCs group. Mice treated without any reagents were assigned as Control, mice transplanted with BMSCs were assigned as BMSCs group. Regulatory …


Developing A Label Propagation Approach For Cancer Subtype Identification Problem, Pinar Güner, Burcu Güngör, Mustafa Coşkun Jan 2022

Developing A Label Propagation Approach For Cancer Subtype Identification Problem, Pinar Güner, Burcu Güngör, Mustafa Coşkun

Turkish Journal of Biology

Cancer is a disease in which abnormal cells grow uncontrollably and invade other tissues. Several types of cancer have various subtypes with different clinical and biological implications. Based on these differences, treatment methods need to be customized. The identification of distinct cancer subtypes is an important problem in bioinformatics, since it can guide future precision medicine applications. In order to design targeted treatments, bioinformatics methods attempt to discover common molecular pathology of different cancer subtypes. Along this line, several computational methods have been proposed to discover cancer subtypes or to stratify cancer into informative subtypes. However, existing works do not …


Rgs1 Serves As An Anti-Tumor Target To Inhibit Proliferation Of Nicn87-Dr Cells And Tumor Growth In Gastric Cancer Mouse Model, Zhixiong Chen, Banglun Liu, Shouru Zhang, Lihui Chen, Yuyu Lv, Hao Sun Jan 2022

Rgs1 Serves As An Anti-Tumor Target To Inhibit Proliferation Of Nicn87-Dr Cells And Tumor Growth In Gastric Cancer Mouse Model, Zhixiong Chen, Banglun Liu, Shouru Zhang, Lihui Chen, Yuyu Lv, Hao Sun

Turkish Journal of Biology

Gastric cancer is becoming the 4th leading cause of cancer-associated death worldwide. The purpose of this study was to investigate the role of RGS1 in gastric cancer in vitro and in vivo. Proliferation, migration, invasion, and colony formation of NCIN87 cells and drug-resistant NCIN87 cells (NCIN87-DR) were determined. Cell apoptosis and cell cycle were examined using a flow cytometry assay. RGS1 gene knock-down vector (pLVshshRGS1) and Xenograft tumor mouse model was generated. RGS1 and epithelial-mesenchymal transition (EMT) associated markers, including E-cadherin (E-cad), N-cadherin (N-cad), Slug, and Vimentin were detected using a western blotting assay. Tumor size of Xenograft tumor mouse …


Influence Of Aerobic Exercise Training On Mice Gut Microbiota In Parkinson's Disease, Tianlun Fan, Xiating Li, Xiang Zhang, Jing Zhang, Lichun Sun, Jingjing Chen, Chuan Fu Jan 2022

Influence Of Aerobic Exercise Training On Mice Gut Microbiota In Parkinson's Disease, Tianlun Fan, Xiating Li, Xiang Zhang, Jing Zhang, Lichun Sun, Jingjing Chen, Chuan Fu

Turkish Journal of Biology

Accumulating evidence shows that gut microbial dysbiosis may represent a risk factor for Parkinson's disease (PD). Exercise has a positive effect on microbiota in general. The effect of aerobic exercise training (AET) on the gut microbial environment in PD remains to be explored. Here, we performed the 16S rRNA gene sequencing on feces from sham operated-mice (sham), PD mice model, and mice receiving AET (AET). Results indicated that AET had no remarkable effect on species richness and bacterial diversity of PD mice. The relative abundance of the Bacteroidetes was reduced, while Firmicutes, Actinobacteria, Lactobacillaceae, Streptococcaceae, Lactobacillus, Streptococcus, Lactococcus, Lysinibacillus, Pelomonas, …


Acceleration Of Slow Autophagy Flux Induced By Arabinofuranosyl Cytidine Improves Its Antileukemic Effectiveness In M-Nfs-60 Cells, Salwa Fouad, Gamal Elsokkary, Abo Bakr Abdel Shakor Jan 2022

Acceleration Of Slow Autophagy Flux Induced By Arabinofuranosyl Cytidine Improves Its Antileukemic Effectiveness In M-Nfs-60 Cells, Salwa Fouad, Gamal Elsokkary, Abo Bakr Abdel Shakor

Turkish Journal of Biology

Arabinofuranosyl cytidine (AraC) is an analog of deoxycytidine used as an anticancer drug for leukemic patients. The effective dose always produces severe complications. The present study investigated the modulation of autophagy and its impact on the cytotoxicity of AraC toward murine myelogenous leukemia cells (M-NFS-60). Autophagy was inhibited by NH4Cl or Bafilomycin A1 or enhanced by amino acid starvation, glucose starvation, mild hyperthermia (41 °C), or rapamycin (Rap). Cells were treated with different concentrations, 0 to 2 µM, of AraC in the presence or absence of autophagy modulators. AraC-induced apoptosis is combined with autophagy, especially at lower concentrations. This autophagy …


Gemcitabine In Combination With Epibrassinolide Enhanced The Apoptotic Response In An Er Stress-Dependent Manner And Reduced The Epithelial-Mesenchymal Transition In Pancreatic Cancer Cells, Pinar Obakan Yerli̇kaya, Leila Mehdizadehtapeh, Özge Rencüzoğullari, Fadina Kuryayeva, Sena Sedef Çevi̇kli̇, Şevval Özağar, Si̇bel Pinar Odabaş, Sude Tunçkol, Hakan Yeti̇m, Ajda Çoker Gürkan, Eli̇f Damla Arisan Jan 2022

Gemcitabine In Combination With Epibrassinolide Enhanced The Apoptotic Response In An Er Stress-Dependent Manner And Reduced The Epithelial-Mesenchymal Transition In Pancreatic Cancer Cells, Pinar Obakan Yerli̇kaya, Leila Mehdizadehtapeh, Özge Rencüzoğullari, Fadina Kuryayeva, Sena Sedef Çevi̇kli̇, Şevval Özağar, Si̇bel Pinar Odabaş, Sude Tunçkol, Hakan Yeti̇m, Ajda Çoker Gürkan, Eli̇f Damla Arisan

Turkish Journal of Biology

Gemcitabine is a broad-spectrum antimetabolite and a deoxycytidine analog recognized as a standard therapy alone or in combination with other antineoplastic agents in the therapy of pancreas cancer. Drug resistance following gemcitabine treatment is a common phenomenon; therefore, combinational therapy models are usually preferred. Pancreatic ductal adenocarcinoma, or pancreas cancer, is the fourth leading cause of cancer-related deaths worldwide. With the increasing incidence of pancreatic cancer every year, the mortality rate is also rising significantly because of late diagnosis, and limited chemotherapy options. Adjuvant chemotherapy after surgical resection is the typical option for the treatment of early pancreatic cancer. Mostly, …


Vars1 Mutations Associated With Neurodevelopmental Disorder Are Located On A Short Amino Acid Stretch Of The Anticodon-Binding Domain, Ayşe Semra Hiz, Seval Kiliç, Güney Bademci̇, Tülay Karakulak, Aybi̇ke Erdoğan, Burcu Özden Yücel, Çi̇ğdem Eresen Yazicioğlu, Şeri̇fe Esra Erdal Bağriyanik, Uluç Yi̇ş, Mustafa Teki̇n, Gökhan Karakülah, Ezgi̇ Karaca Erek, Mehmet Öztürk Jan 2022

Vars1 Mutations Associated With Neurodevelopmental Disorder Are Located On A Short Amino Acid Stretch Of The Anticodon-Binding Domain, Ayşe Semra Hiz, Seval Kiliç, Güney Bademci̇, Tülay Karakulak, Aybi̇ke Erdoğan, Burcu Özden Yücel, Çi̇ğdem Eresen Yazicioğlu, Şeri̇fe Esra Erdal Bağriyanik, Uluç Yi̇ş, Mustafa Teki̇n, Gökhan Karakülah, Ezgi̇ Karaca Erek, Mehmet Öztürk

Turkish Journal of Biology

Majority of 37 human aminoacyl tRNA synthetases have been incriminated in diverse, mostly recessive, genetic diseases. In accordance with this, we uncovered a novel homozygous valyl-tRNA synthetase 1 (VARS1) gene variant, leading to p.T1068M mutation. As in the previously reported VARS1 mutations, the affected individual harboring p.T1068M was experiencing a neurodevelopmental disorder with intractable seizures, psychomotor retardation, and microcephaly. To link this phenotypic outcome with the observed genotype, we structurally modeled human VARS1 and interpreted p.T1068M within the spatial distribution of previously reported VARS1 variants. As a result, we uncovered that p.T1068M is clustered with three other pathogenic …


Scaffolds From Medical Grade Chitosan: A Good Choice For 3d Cultivation Of Mesenchymal Stem Cells, Merve Çapkin Yurtsever, Özge Eki̇n Akdere, Menemşe Gümüşdereli̇oğlu Jan 2022

Scaffolds From Medical Grade Chitosan: A Good Choice For 3d Cultivation Of Mesenchymal Stem Cells, Merve Çapkin Yurtsever, Özge Eki̇n Akdere, Menemşe Gümüşdereli̇oğlu

Turkish Journal of Biology

Chitosan has high biocompatibility, supports proliferation of many cells, and can be a good carrier for various growth factors. However, low attachment ratio and spheroid formation of several stem cell types on plain chitosan scaffolds/films is still a problem. In this study, it was aimed to obtain 3D scaffolds using medical grade chitosan (MC) with a high deacetylation degree (DD ≥ 92.6%) to overcome the spheroid formation of rat adipose tissue derived mesenchymal stem cells (rAdMSCs) on control chitosan (C, DD = 75%-85%) scaffolds. Genipin was used as a biological chemical crosslinker, and glycerol phosphate salt was used both as …


Knockdown Of Death Receptor 5 Antisense Long Noncoding Rna And Cisplatin Treatment Modulate Similar Macromolecular And Metabolic Changes In Hela Cells, Di̇lek Cansu Gürer, İpek Erdoğan Vatansever, Çağatay Ceylan, Bünyami̇n Akgül Jan 2022

Knockdown Of Death Receptor 5 Antisense Long Noncoding Rna And Cisplatin Treatment Modulate Similar Macromolecular And Metabolic Changes In Hela Cells, Di̇lek Cansu Gürer, İpek Erdoğan Vatansever, Çağatay Ceylan, Bünyami̇n Akgül

Turkish Journal of Biology

Background/aim: Despite great progress in complex gene regulatory mechanisms in the dynamic tumor microenvironment, the potential contribution of long noncoding RNAs (lncRNAs) to cancer cell metabolism is poorly understood. Death receptor 5 antisense (DR5-AS) is a cisplatin inducible lncRNA whose knockdown modulates cell morphology. However, its effect on cell metabolism is unknown. The aim of this study is to examine metabolic changes modulated by cisplatin and DR5-AS lncRNA in HeLa cells. Materials and methods: We used cisplatin as a universal cancer therapeutic drug to modulate metabolic changes in HeLa cervix cancer cells. We then examined the extent of metabolic changes …


Mapping Quantitative Trait Loci And Developing First Molecular Marker For Race 5 Of Podosphera Xanthii Resistance In Melon (Cucumis Melo L.), Abdullah Ünlü, İlknur Polat, Aytül Yildirim, Ahmet Naci̇ Onus Jan 2022

Mapping Quantitative Trait Loci And Developing First Molecular Marker For Race 5 Of Podosphera Xanthii Resistance In Melon (Cucumis Melo L.), Abdullah Ünlü, İlknur Polat, Aytül Yildirim, Ahmet Naci̇ Onus

Turkish Journal of Botany

Powdery mildew of melon caused by the Podosphaera xanthii factor is a disease that causes serious yield losses economically in all areas where melon is grown from Asia to Europe and America. The use of resistant varieties for the control of the disease is the most environmentally friendly method. However, traditional methods of melon breeding have made a noteworthy input to resistance varieties improvement, but they have been slow and incompetent in targeting complex powdery mildew disease resistance traits. To overcome these problems and to facilitate breeding programs, molecular markers closely linked to the Pm-R5 gene are needed for marker-assisted …


Molecular Analysis Of The Section Sphagnum (Sphagnaceae): First Study On Turkish Bryophytes Using Nucleotide Sequences Of The Trnl Intron Region, Mesut Kirmaci, Asli Semi̇z, Adi̇le Sari, Özden Özgün Acar, Uğur Çatak, Fulya Fi̇li̇z Jan 2022

Molecular Analysis Of The Section Sphagnum (Sphagnaceae): First Study On Turkish Bryophytes Using Nucleotide Sequences Of The Trnl Intron Region, Mesut Kirmaci, Asli Semi̇z, Adi̇le Sari, Özden Özgün Acar, Uğur Çatak, Fulya Fi̇li̇z

Turkish Journal of Botany

The genus Sphagnum is one of the richest taxa among the Turkish bryophytes. Up to now, it has been represented by 27 taxa in six sections (Sphagnum, Acutifolia, Squarrosa, Subsecunda, Cuspidata, and Rigida). In this study, an identification key for the section Sphagnum was prepared, and the section was investigated using phylogenetic analyses, with a main focus on Turkish bryophytes. This study provides the first sequence data of the trnL intron region for five species of the section Sphagnum from Turkey (namely S. centrale, S. divinum, S. medium, S. palustre, and S. papillosum) to be used in future studies and …


Molecular And Otolith Shape Analyses Of Scorpaena Spp. In The Turkish Seas, Serdar Yedi̇er, Derya Bostanci Jan 2022

Molecular And Otolith Shape Analyses Of Scorpaena Spp. In The Turkish Seas, Serdar Yedi̇er, Derya Bostanci

Turkish Journal of Zoology

This study aims to investigate the discrimination and the phylogenetic relationship of five Scorpaena species (S. elongata, S. maderensis, S. notata, S. porcus, and S. scrofa), sampled from eight locations in the four seas (Mediterranean Sea, Aegean Sea, Black Sea, and Sea of Marmara) in Turkey, using both molecular and otolith shape analyses. Totally, 1360 samples were examined for otolith shape analyses, and 51 of them were also used in the molecular analysis (COI sequences, 652 bp). Eighteen haplotypes were determined in the 5 species of the genus Scorpaena; 3 haplotypes for S. elongata, S. maderensis and S. scrofa, 4 …


Effects Of Ni (Ii) P-Hydroxybenzoate With Caffeine On Metabolic, Antioxidant, Andbiochemical Parameters Of Model Insect Galleria Mellonella L. (Lepidoptera: Pyralidae), Serkan Sugeçti̇, Kemal Büyükgüzel Jan 2022

Effects Of Ni (Ii) P-Hydroxybenzoate With Caffeine On Metabolic, Antioxidant, Andbiochemical Parameters Of Model Insect Galleria Mellonella L. (Lepidoptera: Pyralidae), Serkan Sugeçti̇, Kemal Büyükgüzel

Turkish Journal of Zoology

Many insecticides used against pests cause environmental pollution. Therefore, it is very important to develop new alternative strategies to toxic insecticides. In this study, the physiological and biochemical effects of Ni (II) p-hydroxybenzoate with caffeine on the model insect Galleria mellonella were investigated. In the present study, transferase enzyme activities such as alanine transferase, aspartate transferase and gamma-glutamyl transferase, which regulate amino acid metabolism, were altered in hemolymph of G. mellonella larvae exposed to Ni (II) p-hydroxybenzoate with caffeine. In addition, the activities of metabolic enzymes such as creatine kinase, lactate dehydrogenase, and amylase increased in hemolymph of G. mellonella …


Oxygen Consumption Rates And Respiratory Carbon Losses In Three Species Of Copepods(Acartia Clausi, Calanus Helgolandicus And Limnocalanus Macrurus) During Starvation, Leonid Svetlichny, Maiju Lehtiniemi, Outi Setälä, Anne-Mari Lehto, Larysa Samchyshyna, Yulia Gromova, Melek İşi̇ni̇bi̇li̇r Okyar, Ezgi̇ Emi̇ş Türkeri̇, Kami̇l Mert Eryalçin, Gülşah Can Kayadelen, Ahmet Erkan Kideyş Jan 2022

Oxygen Consumption Rates And Respiratory Carbon Losses In Three Species Of Copepods(Acartia Clausi, Calanus Helgolandicus And Limnocalanus Macrurus) During Starvation, Leonid Svetlichny, Maiju Lehtiniemi, Outi Setälä, Anne-Mari Lehto, Larysa Samchyshyna, Yulia Gromova, Melek İşi̇ni̇bi̇li̇r Okyar, Ezgi̇ Emi̇ş Türkeri̇, Kami̇l Mert Eryalçin, Gülşah Can Kayadelen, Ahmet Erkan Kideyş

Turkish Journal of Zoology

Calanoid copepods with different life cycle strategies demonstrate varied velocity in the utilization of energy resources during starvation. This study analyzes the influence of multiday starvation on the rate of total, basal and active energy metabolism in adult females of two Marmara Sea and one Baltic Sea species of copepods; epiplanktonic Acartia clausi unable to accumulate lipid reserves and mesoplanktonic Calanus helgolandicus with minor lipid reserves in the oil sac (approximately 7% of body volume) and the Baltic Sea copepod Limnocalanus macrurus in quasi-diapausing state with large lipid reserves in the oil sac (approximately 19% of body volume). Initially, total …


Effects Of Vitamin D Administration At The Beginning Of Lactation In Dairy Cows Oninflammatory Response And Liver Metabolism, Feyyaz Kaya, Hasan Batmaz Jan 2022

Effects Of Vitamin D Administration At The Beginning Of Lactation In Dairy Cows Oninflammatory Response And Liver Metabolism, Feyyaz Kaya, Hasan Batmaz

Turkish Journal of Veterinary & Animal Sciences

This study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response. Twenty multiparous Holstein cows were randomly assigned to the experimental (EG) and control group (CG). The EG received 5,000,000 IU vitamin D3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl. Blood samples were taken 24 h after parturition before treatments and at the 3rd, 7th, 14th, and 28th days of lactation. Serum NEFA, BHBA, haptoglobin, serum amyloid A (SAA), ceruloplasmin, calcium, phosphorus, …


The Effect Of Dystocia On Oxidative Stress, Colostral Antibody/Passive Immune Status, Andblood Gases In Damascus Goats And Their Kids, Tuğra Akkuş, Ömer Korkmaz, Bi̇rten Emre, Abuzer Kafar Zonturlu, Peli̇n Fatoş Polat Di̇nçer, Ömer Yaprakci Jan 2022

The Effect Of Dystocia On Oxidative Stress, Colostral Antibody/Passive Immune Status, Andblood Gases In Damascus Goats And Their Kids, Tuğra Akkuş, Ömer Korkmaz, Bi̇rten Emre, Abuzer Kafar Zonturlu, Peli̇n Fatoş Polat Di̇nçer, Ömer Yaprakci

Turkish Journal of Veterinary & Animal Sciences

The present study was conducted to investigate the effect of dystocia on oxidative stress, venous blood gases, and colostrum and serum immunoglobulins G (IgG) in Damascus goats and their kids, respectively. The study sample comprised a total of 40 Damascus goats with of their own 40 kids separated into 2 groups according to the type of birth. Group 1 consisted of goats with eutocia (n = 20) and their kids (n = 20), and Group 2 consisted of goats with dystocia (n = 20) and their kids (n = 20). Blood samples were taken from the goats and their kids …


Relationships Between Famacha Scores And Some Blood Values In Sheep And Goats, Özcan Şahi̇n, İbrahi̇m Ayteki̇n, Sai̇m Boztepe, İsmai̇l Keski̇n, Ali̇ Karabacak, Yasi̇n Altay, Mervan Bayraktar Jan 2022

Relationships Between Famacha Scores And Some Blood Values In Sheep And Goats, Özcan Şahi̇n, İbrahi̇m Ayteki̇n, Sai̇m Boztepe, İsmai̇l Keski̇n, Ali̇ Karabacak, Yasi̇n Altay, Mervan Bayraktar

Turkish Journal of Veterinary & Animal Sciences

In this study, Akkaraman sheep and Hair goats raised extensively on the same farm were scored with the FAMACHA card. Score 1 was not present in both sheep and goats, whereas scores 5 and 2 were not detected in sheep and goats, respectively. While the number of animals with scores of 2, 3, and 4 was 9, 46, and 55 in sheep, the number of animals with 3, 4, and 5 scores in goats was 6, 55, and 41, respectively. In the study, the differences in the amount of RBC, Hct, and Hb in goats according to these score groups …


Investigations On Some Aerobic Bacterial Agents Isolated From Heifers At The Beginning Ofthe First Lactation, Tuncay Çökülgen, Uçkun Sai̇t Uçan Jan 2022

Investigations On Some Aerobic Bacterial Agents Isolated From Heifers At The Beginning Ofthe First Lactation, Tuncay Çökülgen, Uçkun Sai̇t Uçan

Turkish Journal of Veterinary & Animal Sciences

In this study, it was aimed to identify the predominant coagulase-negative staphylococci (CNS) species in subclinical, clinical, and persistent infections in Konya province, to determine various virulence and resistance mechanisms of CNS species within the agelactation level. The research has been carried out in a dairy herd that is free from brucellosis and tuberculosis and uses an automated herd management system. Thirty-two heifers at the beginning of lactation with milk yields of more than 20 liters have been observed in terms of udder infections during the first 1-4 months of lactation. The prevalence of intramammary infections (IMI) and of CNS-caused …


Dental Morphometric Investigation On The Chinchilla (Chinchilla Lanigera) Using A Threedimensionalreconstruction Model, Sema Özkadi̇f, Emrullah Eken, Ayşe Haligür Jan 2022

Dental Morphometric Investigation On The Chinchilla (Chinchilla Lanigera) Using A Threedimensionalreconstruction Model, Sema Özkadi̇f, Emrullah Eken, Ayşe Haligür

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to reveal the morphometric characteristics of the teeth of the chinchilla (Chinchilla lanigera), which are both kept as pet animals and raised for the economic value of their fur, using three-dimensional (3D) reconstructions created from two-dimensional (2D) multidetector computed tomography (MDCT) images and to investigate whether there was a difference between the sexes. A total of 12 chinchillas of both sexes (six males and six females) were used. The teeth reconstructions of the animals were performed with Mimics. 14.1 3D modeling software on the 2D images was taken in the prone position. According to …


Determination Of The Morphometric Characteristics Of Donkey (Equus Asinus)Populations Reared In Turkey, Eser Kemal Gürcan, Serdar Genç, Selçuk Kaplan, Fulya Özdi̇l, Emel Özkan Ünal, Hasan Bulut, Selen Yatkin, Sezen Arat, Mehmet İhsan Soysal Jan 2022

Determination Of The Morphometric Characteristics Of Donkey (Equus Asinus)Populations Reared In Turkey, Eser Kemal Gürcan, Serdar Genç, Selçuk Kaplan, Fulya Özdi̇l, Emel Özkan Ünal, Hasan Bulut, Selen Yatkin, Sezen Arat, Mehmet İhsan Soysal

Turkish Journal of Veterinary & Animal Sciences

This research aims to determine the morphometric characteristics of the donkey (Equus asinus) populations reared in Turkey. For this purpose, live weights and body measurements were collected from 500 donkeys. The donkeys were grouped according to the factors of color, age, sex, and province and the live weights (LW) (kg), withers heights (WH), rump heights (RH), body lengths (BL), chest circumferences (CC), chest depths (CD), front shank circumferences (FSC), head lengths (HL) and ear lengths (EL) (cm) of the donkeys were measured. In the study, the males were found to have higher values of live weight, withers height, rump height, …


The Molecular Prevalence Of Borrelia Burgdorferi, Babesia Spp., And Anaplasma Spp. Inshelter Dogs Of The Thrace Region In Turkey, Nuri̇ Altuğ, Mustafa Necati̇ Muz, Di̇lek Muz, Fulya Altinok Yi̇pel Jan 2022

The Molecular Prevalence Of Borrelia Burgdorferi, Babesia Spp., And Anaplasma Spp. Inshelter Dogs Of The Thrace Region In Turkey, Nuri̇ Altuğ, Mustafa Necati̇ Muz, Di̇lek Muz, Fulya Altinok Yi̇pel

Turkish Journal of Veterinary & Animal Sciences

The study aimed to update the molecular prevalence of some tick-borne pathogens (Borrelia burgdorferi, Babesia spp., and Anaplasma spp.) in the shelter dogs of the Thrace Region, Turkey. The study was carried out on 450 dogs from 7 pet shelters. The individual data of the dogs were recorded, and blood samples were collected in tubes with anticoagulants (EDTA). Then, individual PCR protocols were applied to all samples for the three infective agents. PCR test results recorded for B. burgdorferi is 38.22% (n = 172), 24.22% (n = 109) for Babesia spp., and 21.6% (n = 97) for Anaplasma spp. The …


Genetic Variation At The Olr1, Anxa9, Myf5, Ltf, Igf1, Lgb, Csn3, Pit1, Mbl1,Cacna2d1, And Abcg2 Loci In Turkish Grey Steppe, Anatolian Black, And Eastanatolian Red Cattle, Özden Çobanoğlu, Sena Ardiçli Jan 2022

Genetic Variation At The Olr1, Anxa9, Myf5, Ltf, Igf1, Lgb, Csn3, Pit1, Mbl1,Cacna2d1, And Abcg2 Loci In Turkish Grey Steppe, Anatolian Black, And Eastanatolian Red Cattle, Özden Çobanoğlu, Sena Ardiçli

Turkish Journal of Veterinary & Animal Sciences

Native breeds are excellent sources of genetic variation. Anatolian native breeds are relatives of the first cattle domesticated and are ancestors of many European breeds. Therefore, this study aimed to evaluate the genetic variation of OLR1, ANXA9, MYF5, LTF, IGF1, LGB, CSN3, PIT1, MBL1, CACNA2D1, and ABCG2 markers in Turkish Grey Steppe, Anatolian Black, and East Anatolian Red cattle. The analysis included 367 cattle and the genotyping was performed by the PCR-RFLP. Population genetics indices including heterozygosity, the number of effective alleles, the polymorphism information content, fixation index, and the level of possible variability realization, and moreover, the genetic diversity …


Effects Of Dietary Insect (Ephestia Kuehniella) Egg Meal On Growth Performance And Fattyacid Profile Of Common Carp (Cyprinus Carpio), Levent Doğankaya Jan 2022

Effects Of Dietary Insect (Ephestia Kuehniella) Egg Meal On Growth Performance And Fattyacid Profile Of Common Carp (Cyprinus Carpio), Levent Doğankaya

Turkish Journal of Veterinary & Animal Sciences

The effects of mill moth (Ephestia kuehniella) egg meal (IEM) upon growth performance and fatty acid profile of common carp (Cyprinus carpio) (1.12 ± 0.01 g) were evaluated in triplicate groups for 12 weeks. Three isonitrogenous (35% CP) and isocaloric (17 MJ kg?1) diets were formulated replacing fishmeal with 0% (G-0), 50% (G-50), and 100% (G-100) IEM. The results of the trial indicated that G-50 had the highest growth performance values and a more efficient FCR (1.79). Replacement levels of IEM did not have any significant effect on survival. Total monounsaturated fatty acids (MUFA) were found to be statistically different …


The In Vitro Effect Of Hypochlorous Acid-Metal Nanoparticles Combination On Salmonellaunder Different Temperature Conditions, Serkan Kemal Büyükünal, Karlo Muratoğlu, Ahmet Koluman Jan 2022

The In Vitro Effect Of Hypochlorous Acid-Metal Nanoparticles Combination On Salmonellaunder Different Temperature Conditions, Serkan Kemal Büyükünal, Karlo Muratoğlu, Ahmet Koluman

Turkish Journal of Veterinary & Animal Sciences

Hypochlorous acid (HClO) is an excellent surface disinfectant and classified as nonhazardous but maintaining a steady HClO solution is extremely difficult. This study aimed to mix HClO with various metal nanoparticles (NPs) to improve stability. The efficiency of the prepared solutions against Salmonella Typhimurium, Salmonella Enteritidis, Salmonella Dublin, and Salmonella Infantis was assessed using the culture method in five distinct experimental groups at varying temperatures (4 °C, 10 °C, 25 °C, 40 °C, and 50 °C). The type of metal NPs, HClO, and application temperatures utilized in the combined solutions for bacterial decontamination did not result in a significant difference …


Acute Phase Proteins, Endocrine And Productive Responses Of Laying Hens To Heat Stress, Amani Aldawood, Hosam Altamimi Jan 2022

Acute Phase Proteins, Endocrine And Productive Responses Of Laying Hens To Heat Stress, Amani Aldawood, Hosam Altamimi

Turkish Journal of Veterinary & Animal Sciences

This study was designed to characterize changes in the acute phase proteins (APPs), hormones parallel to performance, and egg quality traits in laying hens exposed to heat stress (HS). A total of 120 sixteen-week-old Lohmann hens was allowed an adaptation period of 5 weeks in 3 different rooms at 21 °C. The hens were then exposed to one of three climatic thermal treatments over the next 6 weeks; thermoneutrality (TN, 21 °C), constant (C-HS, 28 °C), and cyclic HS (HS, 20 h/d at 28 ± 1 °C and 4 h/d at 33 ± 1 °C). Blood samples were weekly obtained, …


Changes In Serum Pon1 Activity, Gene Expression And Their Association With Lipid Profile Parameters In Healthy Darehshori Neonatal Foals: A Preliminary Study, Rouzbeh Razavi Dehkordi, Gholam Ali Kojouri, Behnaz Karimi, Ali Mohammad Ahadi Jan 2022

Changes In Serum Pon1 Activity, Gene Expression And Their Association With Lipid Profile Parameters In Healthy Darehshori Neonatal Foals: A Preliminary Study, Rouzbeh Razavi Dehkordi, Gholam Ali Kojouri, Behnaz Karimi, Ali Mohammad Ahadi

Turkish Journal of Veterinary & Animal Sciences

Paraoxonase 1 (PON1) contributes to the antioxidant mechanisms that prevent lipoprotein oxidation and act as a negative acute-phase protein. This study aimed to evaluate changes in serum PON1 activity, the leukocyte PON1 gene expression, as well as lipid profile tests (LDL, HDL, triglyceride, and cholesterol) in 16 healthy Darehshori newborn foals up to 60 days of life. Blood samples were collected at 1, 7, 15, 30, and 60 days used for detecting biochemical parameters, PON1 activity, and, and its gene expression, using realtime RT-PCR. Low levels of PON1 activity were observed at birth, which increased significantly with increasing age at …


The Effect Of Nongenetic Factors On Calf Birth Weight And Growth Performance In Anatolian Buffaloes, Kürşat Alkoyak, Sezer Öz Jan 2022

The Effect Of Nongenetic Factors On Calf Birth Weight And Growth Performance In Anatolian Buffaloes, Kürşat Alkoyak, Sezer Öz

Turkish Journal of Veterinary & Animal Sciences

The aim of the current study is to determine the growth performances of Anatolian buffaloes such as birth weight (BW$_{0}$), body weight at 6 months (BW$_{6}$), body weight at 12 months (BW$_{12}$), average daily weight gain from birth to 6 months (ADG$_{0 - 6}$), average daily weight gain from birth to 12 months (ADG$_{0 - 12}$) and average daily weight gain from 6 to 12 months (ADG$_{6 - 12}$), and to identify various nongenetic factors affecting these traits. In the study, the data of 2821 head buffalo calves born from buffaloes bred from the Anatolian Buffalo Breeding Project in Bartın …


Computed Tomography And Osteological Examination Of The Nuchal Perforations In Byzantine Cattle Skulls, Vedat Onar, Aleksander Chroszcz, Dominik Poradowski, Nazan Gezer İnce, Mehmet Ali̇ Polat, Rahmi̇ Asal Jan 2022

Computed Tomography And Osteological Examination Of The Nuchal Perforations In Byzantine Cattle Skulls, Vedat Onar, Aleksander Chroszcz, Dominik Poradowski, Nazan Gezer İnce, Mehmet Ali̇ Polat, Rahmi̇ Asal

Turkish Journal of Veterinary & Animal Sciences

This study presents computed tomography (CT) and osteological observations of nuchal perforations in the Middle-Late Byzantine cattle skulls, unearthed from Yenikapı Metro and Marmaray excavations (ancient Theodosius harbour), İstanbul, Türkiye. A total of 17 skulls with perforations of various size, ranging from elliptical to triangular, located in the nuchal (posterior) region of protuberantia intercornualis were examined. Rounded edges and smooth inner walls of these perforations indicated that they were formed when the animals were alive (ante mortem). The CT helped to understand the details of the caudal and dorsal part of head as well as the relationships between these perforations …


The Effects Of Polymorphisms In The Cx3cr1 Gene On The Development Of Canine Hipdysplasia, Sertaç Atalay, Süleyman Kök Jan 2022

The Effects Of Polymorphisms In The Cx3cr1 Gene On The Development Of Canine Hipdysplasia, Sertaç Atalay, Süleyman Kök

Turkish Journal of Veterinary & Animal Sciences

Hip dysplasia, caused by both environmental and genetic components, is a common disorder characterized by hip instability in humans and dogs. Unfortunately, the genetic mechanisms that cause the disease in both have not been fully determined. The aim of this study was polymorphisms in the exon 2 and 3' UTR regions of the CX3CR1 gene were determined and their effects on the development of Canine Hip Dysplasia (CHD) in three dog breeds (German Shepherd, Belgian Malinois, Labrador Retriever). For this purpose, a case -control study was designed with 172 dogs in Dog Breeding and Training Center (DBTC) in Turkey. Each …