Life Sciences Commons^™

Review Of Racial Disparities: Healthcare, Health Outcomes, And Outreach Programs, Lauren Bagneris

Honors Capstones

No abstract provided.

Investigating Antiviral Rnai Pathways In Caenorhabditis Elegans Through The Context Of The Nsl Complex And Its Subunits Sumv-1, Mys-2, And Ogt-1, Alexandre Van Biersel

Honors Capstones

No abstract provided.

Generating Transgenic Animals To Understand The Role Of The Huckebein (Hkb) Transcription Factor In Positioning Tissue Invagination, Samantha Leigh Vercher

Honors Capstones

No abstract provided.

Correlation Between Leaf Morphology And Environmental Niche In The Eucentropogonid Subclade Of Species-Rich Neotropical Bellflowers (Campanulaceae), Ayah Ibrahim

Honors Capstones

No abstract provided.

An Investigation Of The Proline Biosynthesis Pathway In Response To Osmotic Stress In Tigriopus Californicus, Yasmeen Kawji

Honors Capstones

No abstract provided.

Genomics And Population History Of Black-Headed Bulbul (Brachypodius Atriceps) Color Morphs, Subir B. Shakya

LSU Doctoral Dissertations

Intraspecific polymorphism in birds, especially color polymorphism, is an area of active research in evolutionary biology. In this dissertation, I applied WGS to uncover the potential genetic underpinnings of color polymorphism in the Black-headed Bulbul (Brachypodius atriceps) of Southeast Asia. This species was selected because of the heterogeneous dispersion of two morphs across its range: a yellow form predominating on mainland Asia and the Greater Sunda Islands and a gray morph on two islands—Bawean and Maratua.

I approached this project from three angles. First, I reconstructed the phylogeny of the bulbul family, Pycnonotidae, to examine patterns of coloration …

Taxonomy And Systematics Of The New Zealand Pselaphini (Coleoptera: Staphylinidae: Pselaphinae), Brittany Elin Owens

LSU Doctoral Dissertations

The New Zealand (NZ) Pselaphini was revised at the species level, a phylogenetic analysis was performed using morphological data, and first steps were taken towards the construction of a molecular analysis of the tribe. Eight new genera and 33 new species were discovered from specimens collected from the NZ mainland, offshore islands, Chatham Islands and the Subantarctic Islands. Of the 13 species originally described in the genus Pselaphus by Thomas Broun during the late 19^th and early 20^th centuries, all were either reassigned to the genera Pselaphaulax and Pselaphogenius, or were placed into new genera. Three names …

Investigating The Role Of Torc1 And The Transcription Factor Sfp1p In The Regulation Of Hmo1 Gene In Saccharomyces Cerevisiae, Mathew Damien Smith

LSU Master's Theses

HMGB proteins are eukaryotic, chromatin-associated proteins that play roles in both DNA dynamics and transcription regulation. Hmo1p is an HMGB protein in Saccharomyces cerevisiae that behaves somewhat like a hybrid between mammalian HMGB proteins and the metazoan linker histone H1. mTORC1, a protein complex containing the Tor1p kinase and a major regulator of cellular growth, is inhibited by both rapamycin and stress. It has also been shown to not only associate with Hmo1p at various gene promoters, but also regulate the HMO1 gene itself through direct binding. In this study, the Hmo1p-mTORC1 relationship was further investigated through two questions: 1) …

Functions Of Cdk/Cyclin Complexes In Endoreplication Regulation By The Cdk Inhibitor Siamese, Kai Wang

LSU Doctoral Dissertations

Arabidopsis trichome (leaf hair) is a specialized single cell extended from epidermal cell on the leaves, which is a typical endoreplication and is also known as endoreduplication. Several D-type cyclins were tested to check the cell division in trichome, and the trichome expressing either CYCB1;2 or CDKB2;2 cannot trigger cell division, even if simultaneous expression of CYCB1;2 and CDKB2;2 failed to produce mitosis in trichome. Only CYCD3;1 specifically promotes multicellular trichome. cdkb1;1cdbk1;2 double mutants and sim cdkb1;1cdkb1;2 triple mutants exhibit the phenotype similar to the wild type and very limited cell division respectively. Overexpression of a CDKB1;1 dominant-negative construct that …

Natural Variation And Evolutionary Responses To Climate Change Stressors In Marine Invertebrates, Joanna Sarah Griffiths

LSU Doctoral Dissertations

Our rapidly changing climate is putting many species at risk of extinction and there is an urgent need to understand how species will respond to these changes. In this dissertation, I evaluate how three species of marine invertebrates (corals, oysters, and copepods) respond to stressful conditions in their current environments and how plasticity and evolutionary adaptation could alter their response to future climate change stressors. I first employed a space for time study to elucidate population differences in the response of cold-water corals, Balanophyllia elegans, to future ocean acidification. I found evidence that upwelling history (natural low pH exposure) influences …

Effects Of Freshwater Inflow On Nekton Assemblages And Blue Crab Populations In Southeastern Louisiana, Caleb Benjamin Taylor

LSU Master's Theses

Estuaries along the northern Gulf of Mexico represent some of the most productive ecosystems in the world, providing vital habitat for many recreationally and commercially valuable species, including the blue crab, Callinectes sapidus. The mixing of fresh river and saline ocean water in coastal estuaries contribute to this productivity. Dominated by large river influences and consisting of multiple estuaries, Louisiana contributes the largest commercial fishery in the Gulf of Mexico, and remains, on average, the largest supplier of blue crabs in the nation. However, across southeast Louisiana, freshwater flow is largely dependent on Mississippi River discharge, which is highly …

Testing The Interaction Between The Cystic Fibrosis Transmembrane Regulator And Anoctamin 1 In Amacrine Cells Of Gallus Gallus Retinas, Hailey Danielle Simpson

Honors Capstones

No abstract provided.

Investigating The Origins Of Facultative Heterotrophy In Cyanobacteria, Emily A. Brown

Honors Capstones

No abstract provided.

Gnrh As A Neuromodulator In Midbrain Sensory Regions During The Female Cichlid Reproductive Cycle, Mark Anthony Maier Ii

Honors Capstones

No abstract provided.

Role Of Coastal Environmental Conditions During Austral Winter On Plankton Community Dynamics And The Occurrence Of Pseudo-Nitzschia Spp. And Domoic Acid In Inhambane Province, Mozambique, Holly Kelchner

LSU Master's Theses

Harmful algal blooms (HABs) are increasing globally in frequency, persistence, and geographic extent. HABs pose a threat to economic stability, and ecosystem and human health. To date no incidences of marine toxins produced by phytoplankton have been recorded in Mozambique, which may be due to the absence of a monitoring program and general awareness of the potential threat. This study is the first documentation of the occurrence of a neurotoxin, domoic acid (DA), produced by the diatom genus Pseudo-nitzschia spp. along the east coast of Africa. The coast of Inhambane Province is a biodiversity hotspot where year-round Rhincodon typus (whale …

Phenotypic And Genotypic Characterization Of Aroma And Cercospora Janseana Resistance In U.S. Rice, Christopher Keith Addison

LSU Doctoral Dissertations

Rice is a staple food for over one-third of the world’s population. With the increasing population, plant breeders must continue to breed for improved varieties. The utilization of markers to applied breeding program can increase the efficiency of selection for key traits. The targeted traits for this research include grain aroma and resistance to the fungal disease narrow brown leaf spot (Cercospora janseana). Our objective was to characterize SNP diversity across the BADH2 gene in publicly available sequence data of a collection of 2,932 rice varieties was characterized to determine the number of gene haplotypes in O. sativa. …

Assessment Of Soil Protein And Refractory Soil Organic Matter Across Two Chronosequences Of Newly Developing Marshes In Coastal Louisiana, Usa, Stuart Alexander Mcclellan

LSU Doctoral Dissertations

The impacts of sea-level rise and hydrologic manipulation are threatening the stability of coastal marshes throughout the world, thereby increasing the potential for re-mineralization of soil organic matter (SOM) in these systems. Such threats have prompted marsh restoration efforts, particularly in coastal Louisiana, yet it is unclear how the slowly decomposing (refractory) and quickly decomposing (labile) fractions of SOM may be differentially affected by different approaches to marsh restoration. Additionally, otherwise labile compounds may accumulate in the soil via a range of protective mechanisms, including rapid burial and association with organic compounds that are thought to enhance soil aggregation, such …

Developing A Fanbase In Niche Sport Markets: An Examination Of Nhl Fandom And Social Sustainability In The Sunbelt, Brandon Mastromartino, Tyreal Y. Qian, Jerred J. Wang, James J. Zhang

Faculty Publications

In the modern day sport marketplace, professional sport teams face tough competition to build and sustain a viable fan base. This study sought to address three research questions: (a) what are the factors that contribute to the socialization of sports fans in niche sport markets? (b) How do team-led and fan-led initiatives work to socialize fans? Finally, (c) to what extent do the socialization factors affect identify as a sports fan for a niche sport and overall fan consumption behavior? A questionnaire was administered to 535 NHL fans and data were analyzed through conducting an Exploratory Factor Analysis, Exploratory Factor …

Synthesis And Preliminary Ex Vivo Testing Of Sirna Targeting Tcrb: A Proposed Therapy For The Treatment Of Autoimmunity, Nicholas J. Magazine

LSU Doctoral Dissertations

Abstract

Background:

As of 2018, the United States National Institutes of Health estimate that over half a billion people worldwide are affected by autoimmune disorders. Though these conditions are prevalent, treatment options remain relatively poor, relying primarily on various forms of immunosuppression which carry potentially severe side effects and often lose effectiveness overtime. Given this, new forms of therapy are needed. We propose small-interfering RNA (siRNA) for hypervariable regions of the T-cell receptor β-chain gene (TCRb) as a highly targeted, novel means of therapy for the treatment of autoimmune disorders.

Objectives:

To develop methods to produce siRNA targeting …

Soil Health On A Small-Scale Sustainable Vegetable Farm In South Louisiana, Allison Guidroz

LSU Master's Theses

One of the biggest challenges facing the world today is the need to provide nutritious food to an ever-growing population in a way that does not compromise the ecosystem services of the soil that are necessary for life. The evidence for widespread degradation of the soil has been a major contributor in the increased interest in soil health. Most of the research in soil health has focused on field crops, which has led to a gap in the research of soil health on vegetable cropping systems. This objective of this study was to analyze the health of the soil on …

Evaluation Of Space Use And Movement By Wild Turkey (Meleagris Gallopavo) During Extreme Climatic Disturbances And Annual Phenological States, David J. Moscicki

LSU Master's Theses

Space use is driven by both intrinsic and extrinsic factors across space and time. Meaning a species demography and habitat requirements may vary across landscapes. Recent studies on wild turkeys (Meleagris gallopavo spp., hereafter turkey) have shown both direct and indirect demographic impacts of climatically driven events on turkey populations. Similarly, there is an abundance of information documenting turkey demographic parameters and space use, but few studies have addressed breeding phenology in great detail. We evaluated the impact on space use and movement patterns of Eastern wild turkeys (M. g. silvestris; n = 20) and Rio Grande wild …

Impacts Of The Deepwater Horizon Oil Spill On Reproduction And Ontogeny Of Gulf Killifish (Fundulus Grandis), Charles Alexander Brown

LSU Doctoral Dissertations

On April 20, 2010, the Deepwater Horizon oil spill released an estimated 779 million liters of Macondo-252 crude oil into the Gulf of Mexico, making it the largest marine oil spill in history. Over a thousand kilometers of marshland that many species of fish use as a spawning grounds and nurseries was oiled, exposing breeding adult fish and their offspring to oil. My dissertation investigates the impacts of the Deepwater Horizon oil spill and associated remediation efforts on the reproduction and ontogeny of a sentinel ecotoxicological species, the Gulf killifish (Fundulus grandis). Concerns were raised regarding use of …

Sodium Propionate And Sodium Butyrate Promote Fatty Acid Oxidation In Hepg2 Cells Under Oxidative Stress, Kristina Jazmin Cook

LSU Doctoral Dissertations

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disturbances that includes simple steatosis, non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and liver cancer. NAFLD affects individuals that consume the typical Western diet consisting of high levels of fats and carbohydrates. The increase in circulating free fatty acids, palmitate and oleate, or lipopolysaccharides (LPS), induce oxidative stress and pro-inflammatory cytokine production in the liver, which all contribute to NAFLD progression. In this study, we are evaluating the mRNA expression of genes associated with fatty acid oxidation (FAO) and the protein expression of pro-inflammatory cytokines related to NAFLD using the HepG2 human liver …

Reproductive Biology And Trophic Niche Of Hardhead Catfish In The Northern Gulf Of Mexico, Lucas G. Pensinger

LSU Master's Theses

Generally, marine fishes have very high fecundity with each female producing many small eggs which hatch into small larvae. However, Ariopsis felis, a species of marine catfish common to coastal Louisiana, has low fecundity and produces the largest eggs of the teleost fishes. Despite wide range and generally high abundance, we know very little of A. felis biology and population. The few existing studies of A. felis are older and often have questionable or unclear methodology.

I examined four aspects of A. felis reproductive biology: 1) reproductive timing,

2) fecundity, 3) length at first maturity, and 4) mouth brooding. …

Louisiana Agriculture Winter, 2020, Lsu Agcenter

Louisiana Agriculture

No abstract provided.

Susceptibility Of Swine Cells And Domestic Pigs To Sars-Cov-2, David A. Meekins, Igor Morozov, Jessie D. Trujillo, Natasha N. Gaudreault, Dashzeveg Bold, Mariano Carossino, Bianca L. Artiaga, Sabarish V. Indran, Taeyong Kwon, Velmurugan Balaraman, Daniel W. Madden, Heinz Feldmann, Jamie Henningson, Wenjun Ma, Udeni B. R. Balasuriya, Juergen A. Richt

Faculty Publications

No abstract provided.

Artificial Intelligence And Covid-19: Deep Learning Approaches For Diagnosis And Treatment, M. B. Jamshidi, A. Lalbakhsh, J. Talla, Z. Peroutka, F. Hadjilooei, P Lalbakhsh, M. Jamshidi, L. La Spada, M. Mirmozafari, M. Dehghani, A. Sabet, Sa. Roshani, So. Roshani, N. Bayat-Makou, B. Mohamadzade, Z. Malek, A. Jamshidi, S. Kiani, H. Hashemi-Dezaki, W. Mohyuddin

Faculty Publications

COVID-19 outbreak has put the whole world in an unprecedented difficult situation bringing life around the world to a frightening halt and claiming thousands of lives. Due to COVID-19 & x2019;s spread in 212 countries and territories and increasing numbers of infected cases and death tolls mounting to 5,212,172 and 334,915 (as of May 22 2020), it remains a real threat to the public health system. This paper renders a response to combat the virus through Artificial Intelligence (AI). Some Deep Learning (DL) methods have been illustrated to reach this goal, including Generative Adversarial Networks (GANs), Extreme Learning Machine (ELM), …

Exhibition "Louisiana's Natural Treasure: Margaret Stones, Botanical Artist", Leah Wood Jewett, John D. Miles, Christina Riquelmy

Special Collections

In 2020, LSU Libraries Special Collections presented the exhibition “Louisiana’s Natural Treasure: Margaret Stones, Botanical Artist” at Hill Memorial Library, featuring selected original watercolor paintings and archival materials related to the Native Flora of Louisiana project.

A native of Australia, Margaret Stones (1920-2018) achieved an acclaimed international career that spanned three continents. Commissioned by LSU and funded by private donations, more than 200 watercolor drawings of Louisiana plants produced by Stones during the 1970s and 1980s are among the most treasured holdings of LSU Libraries Special Collections.

The Native Flora of Louisiana project was grounded in a long historical tradition …

Effects Of Cryopreservation And Next Generation Sequencing Of Adipose Derived Stem Cells, Mulla Shahensha Shaik

LSU Doctoral Dissertations

The research in this thesis is divided into two areas. 1) Studying the effects of cryopreservation and developing freezing protocols suitable for adipose derived stem cells and 2) Identifying the underlying mechanisms involved in the differentiation of ASCs especially into osteogenesis and endothelial-genesis using next generation sequencing.

In the part one (Chapter 2 and 3), a novel protocol to freeze ASCs and the effects of long-term cryopreservation on ASCs were studied. Heat shocking ASCs at 43°C for 1 hour resulted in the temporal expression of HSPs particularly HSP70 and HSP32 to reach maximum expression at 3 hours post heat shock …

Trouble At Old River: An Economic Evaluation Of An Avulsion On United States Soybean Trade, Patrice Maria Lazard

LSU Master's Theses

The Mississippi River is an essential asset to agricultural trade given that its existence contributes to a cost-efficient transportation system. Barge travel allows large amounts of soybeans and other bulk commodities to be transported at low costs. Currently, barge costs are the lowest relative to those of other modes. Although there has been increasing competition for soybean shares from other countries in the global market, low transportation costs of soybeans, grain, and other oilseed crops allow the United States to retain its competitive advantage in the world soybean market. The Mississippi River’s urgency to change course and possibly eliminate barge …