Chemical Engineering Commons^™

2016-2017 Che Newsletter, Department Of Chemical Engineering, Michigan Technological University

Department of Chemical Engineering Newsletters

Table of Contents

• Department
• Convocation
• Student News
• Faculty
• Alumni & Friends

Detecting Overpressure Zones By Using Model Based Inversion In Kupe Field, New Zealand, Timucin Cakir

Dissertations, Master's Theses and Master's Reports

Overpressure is a significant parameter during a drilling process in oil exploration. This phenomenon happens when pore pressure exceeds the limit of hydrostatic pressure in a formation and causes drastic hazards such as blow outs while drilling. This thesis focuses on the determination of possible overpressure areas and studies at three wells in Kupe Field, which is considered to be a natural-gas field in Taranaki Basin. In an effort to identify potential overpressure zones at the Kupe Field, acoustic impedance responses of 3D seismic data for three wells, along with their well log responses were evaluated.

Seismic inversion plays an …

Controlling Properties Of Agglomerates For Chemical Processes, Joseph A. Halt

Dissertations, Master's Theses and Master's Reports

Iron ore pellets are hard spheres made from powdered ore and binders. Pellets are used to make iron, mainly in blast furnaces. Around the time that the pelletizing process was developed, starch was proposed as a binder because it’s viscous, adheres well to iron oxides, does not contaminate pellets and is relatively cheap. In practice, however, starch leads to weak pellets with rough surfaces – these increase the amount of dust generated within process equipment and during pellet shipping and handling. Thus, even though the usual binder (bentonite clay) contaminates pellets, pelletizers prefer it to starch or other organics.

This …

Surface Enabled Lab-On-A-Chip (Loc) Device For Protein Detection And Separation, Zhichao Wang

Dissertations, Master's Theses and Master's Reports

Sensitive and selective chemical/biological detection/analysis for proteins is essential for applications such as disease diagnosis, species phenotype identification, product quality control, and sample examination. Lab-on-a-chip (LOC) device provides advantages of fast analysis, reduced amount of sample requirements, and low cost, to magnificently facilitate protein detection research. Isoelectric focusing (IEF) is a strong and reliable electrophoretic technique capable of discerning proteins from complex mixtures based on the isoelectric point (pI) differences. It has experienced plenty of fruitful developments during previous decades which has given it the capability of performing with highly robust and reproducible analysis. This progress has made IEF devices …

Techno-Economic And Life Cycle Assessments Of Biofuel Production From Woody Biomass Through Torrefaction-Fast Pyrolysis And Catalytic Upgrading, Olumide Winjobi

Dissertations, Master's Theses and Master's Reports

Biofuel production through fast pyrolysis of biomass is a promising conversion route in the production of biofuels compatible with existing technology. The bio-oil produced from fast pyrolysis is a versatile feedstock that can be used as a heating oil or upgraded to a transportation hydrocarbon biofuel. Comparative study of a one-step, fast pyrolysis only pathway and a two-step torrefaction-fast pyrolysis pathway was carried out to evaluate the effect of torrefcation on (i) the minimum selling price of biofuel and (ii) the potential life cycle GHG emissions of the biofuel production pathway.

To produce bio-oil which can serve as a substitute …

Catalytic Hydrotreatment For The Development Of Renewable Transportation Fuels, Lilu Funkenbusch

Dissertations, Master's Theses and Master's Reports

Biologically-derived feedstocks are a highly desirable source of renewable transportation fuel. They can be grown renewably and can produce fuels similar in composition to conventional fossil fuels. They are also versatile and wide-ranging. Plant oils can produce renewable diesel and wood-based pyrolysis oils can be made into renewable gasoline. Catalytic hydrotreatment can be used to reduce the oxygen content of the oils and increase their viability as a “drop-in” transportation fuel, since they can then easily be blended with existing petroleum-based fuels. However, product distribution depends strongly on feedstock composition and processing parameters, especially temperature and type of catalyst. Current …

Electrospun Nanofibers As Neural Guidance Scaffolds, Michael Mullins

TechTalks

Highly-aligned electrospun PolyLactic-L-Acid (PLLA) nanofibers have been shown to promote and direct the axonal outgrowth of Central Nervous System (CNS) neurons. Aligned fibers deposited on 3D printed stages have been tested in vitro using chick Dorsal Root Ganglia (DRG's), and show highly directed neurite growth with improved extension. In vivo studies on rats indicate that similar results are attained, with substantial regrowth of fully transected spinal cords. Extension of these studies to new generation of coaxial nanofiber scaffolds which allow electrical stimulation are in progress.

Inhibition Of Microbial Biofuel Production In Drought-Stressed Switchgrass Hydrolysate, Rebecca Garlock Ong, Alan Higbee, Scott Bottoms, Quinn Dickinson, Dan Xie, Scott A. Smith, Jose Serate, Edward Pohlman, Arthur Daniel Jones, Joshua J. Coon, Trey S. Kato, Gregg R. Sanford, Dustin Eilert, Dustin G. Oates, Jeff S. Piotrowski, Donn M. Bates, David Cavalier, Yaoping Zhang

Department of Chemical Engineering Publications

Background:

Interannual variability in precipitation, particularly drought, can affect lignocellulosic crop biomass yields and composition, and is expected to increase biofuel yield variability. However, the effect of precipitation on downstream fermentation processes has never been directly characterized. In order to investigate the impact of inter-annual climate variability on biofuel production, corn stover and switchgrass were collected during 3 years with significantly different precipitation profiles, representing a major drought year (2012) and 2 years with average precipitation for the entire season (2010 and 2013). All feedstocks were AFEX (ammonia fiber expansion)-pretreated, enzymatically hydrolyzed, and the hydrolysates separately fermented using xylose-utilizing strains …

Recent Approaches In Designing Bioadhesive Materials Inspired By Mussel Adhesive Protein, Pegah Kord Forooshani, Bruce P. Lee

Department of Biomedical Engineering Publications

Marine mussels secret protein-based adhesives, which enable them to anchor to various surfaces in a saline, intertidal zone. Mussel foot proteins (Mfps) contain a large abundance of a unique, catecholic amino acid, Dopa, in their protein sequences. Catechol offers robust and durable adhe-sion to various substrate surfaces and contributes to the curing of the adhesive plaques. In this article, we review the unique features and the key functionalities of Mfps, catechol chemistry, and strategies for preparing catechol-functionalized poly- mers. Specifically, we reviewed recent findings on the contributions of various features of Mfps on interfacial binding, which include coacervate formation, surface …

Experimental And Theoretical Investigation Of Sustainable Fast Pyrolysis Biofuels From Woody Biomass, Bethany Jean Klemetsrud

Dissertations, Master's Theses and Master's Reports

Biofuels are an important advancement in alternative energy that can provide substantial environmental benefits compared to their conventional fossil fuel counterparts Said benefits are usually measured using life cycle assessments. However, it is not well understood yet how different methodological choices such as system boundaries, biomass feedstocks, conversion pathways, geographical data, etc. affect the conclusions drawn from biofuels LCA. This research shows large variability in life cycle assessment results and limits comparison across different biofuel pathways due to methodological choices set forth by policy and certification schemes. Advanced biofuels have not reached large scale production due to a limited understanding …

Purification And Recovery Of Infectious Virus Particles Using Osmolyte Flocculation, Ashish Saksule

Dissertations, Master's Theses and Master's Reports

Viral infectious diseases cause millions of deaths and severe illness all around the world affecting public health and economics. Viral vaccines are helping to fight against viral diseases, but current vaccines are expensive and unavailable, especially in poor and developing countries. When measuring the entire manufacturing processing, the downstream processing of vaccines is the major cost of production. Our goal for this research is to develop a low-cost alternative downstream processing platform for new vaccine manufacturing infrastructures. We have developed a novel osmolyte flocculation method for viral particles. To create a platform purification for several types of viral particles, we …

A Petrophysical Evaluation For Permeability Of A Gas Reservoir In The Taranaki Basin, New Zealand, Musa Cetin

Dissertations, Master's Theses and Master's Reports

The goal of this study was to evaluate permeability and study the controls on permeability in a gas saturated formation. Conventional well logs, mineral identification crossplots and empirical models were applied to analyze different lithologic and diagenetic features and to examine the effect that these features may have on the reservoir. An unusual feature was observed, and required detailed examination: there existed (in two wells) five zones of lower resistivity (higher water saturation) above the gas-water contact. This is unexpected, as above that contact, the water is usually at irreducible water saturation. I conclude that the lower resistivity (the higher …

An Experimental Investigation Into The Effect Of Particulate Matter On Nox Reduction In A Scr Catalyst On A Dpf, Saksham Gupta

Dissertations, Master's Theses and Master's Reports

The study of NO_x reduction across the SCRF^® is presented in this report to understand the inlet and outlet NO, NO₂, NH₃ species from the SCRF^®. The SCRF^® is a prototype SCR catalyst on a Diesel Particulate Filter (DPF) that reduces NOx and PM at the downstream location. The SCRF^® reduces the packaging volume of the aftertreatment components in order to reduce the cost, volume and weight of the aftertreatment system. A total of 12 experiments were performed on a Cummins ISB 2013 280 hp engine and the aftertreatment system. The …

Strategies For The Production Of Cell Wall-Deconstructing Enzymes In Lignocellulosic Biomass And Their Utilization For Biofuel Production, Sang-Hyuck Park, Rebecca Garlock Ong, Mariam Sticklen

Department of Chemical Engineering Publications

Microbial cell wall-deconstructing enzymes are widely used in the food, wine, pulp and paper, textile, and detergent industries and will be heavily utilized by cellulosic biorefineries in the production of fuels and chemicals. Due to their ability to use freely available solar energy, genetically engineered bioenergy crops provide an attractive alternative to microbial bioreactors for the production of cell wall-deconstructing enzymes. This review article summarizes the efforts made within the last decade on the production of cell wall-deconstructing enzymes in planta for use in the deconstruction of lignocellulosic biomass. A number of strategies have been employed to increase enzyme yields …

Life-Cycle Energy And Ghg Emissions Of Forest Biomass Harvest And Transport For Biofuel Production In Michigan, Fengli Zhang, Dana M. Johnson, Jinjiang Wang

College of Business Publications

High dependence on imported oil has increased U.S. strategic vulnerability and prompted more research in the area of renewable energy production. Ethanol production from renewable woody biomass, which could be a substitute for gasoline, has seen increased interest. This study analysed energy use and greenhouse gas emission impacts on the forest biomass supply chain activities within the State of Michigan. A life-cycle assessment of harvesting and transportation stages was completed utilizing peer-reviewed literature. Results for forest-delivered ethanol were compared with those for petroleum gasoline using data specific to the U.S. The analysis from a woody biomass feedstock supply perspective uncovered …

Ring-Opening Polymerization Of Ε-Caprolactone Initiated By Ganciclovir (Gcv) For The Preparation Of Gcv-Tagged Polymeric Micelles, Alicia J. Sawdon, Ching-An Peng

Michigan Tech Publications, Part 1

Ganciclovir (GCV) is a nucleoside analogue with antiviral activity against herpes viral infections, and the most widely used antiviral to treat cytomegalovirus infections. However, the low bioavailability and short half-life of GCV necessitate the development of a carrier for sustained delivery. In this study, guanosine-based GCV was used as the initiator directly in ring-opening polymerization of ε-caprolactone (ε-CL) to form hydrophobic GCV-poly(caprolactone) (GCV-PCL) which was then grafted with hydrophilic chitosan to form amphiphilic copolymers for the preparation of stable micellar nanoparticles. Successful synthesis of GCV-PCL and GCV-PCL-chitosan were verified by ¹H-NMR analysis. Self-assembled micellar nanoparticles were characterized by dynamic …

Electrochemical Processes In Microfluidics Systems Under Ac Electric Fields, Ran An

Dissertations, Master's Theses and Master's Reports - Open

Alternating current (AC) electric signal has been widely applied in microfluidic systems to induce AC electrokinetic behavior. AC electrokinetic phenomena including AC electrophoresis, AC dielectrophoresis, AC electroosmosis flow and AC electrothermal flow are widely applied in (bio)particle sorting, separation and concentration and micropumps. However, numbers of non-ideal AC electrokinetic behaviors have been reported: human erythrocyte deformation in AC dielectrophoresis system has been observed; flow reversal in AC electroosmosis flow pumps has also been reported. In this dissertation, a systematic study on human erythrocyte crenation in AC dielectrophoresis system was firstly conducted. Multiple possible physical mechanisms inducing cell crenation including temperature, …

The Dispersion And Selective Flocculation Of Hematite Ore, Howard James Haselhuhn Iii

Dissertations, Master's Theses and Master's Reports - Open

Iron ore is one of the most important ores in the world. Over the past century, most mining of iron ore has been focused on magnetite (Fe3O4). As the name suggests, magnetite is magnetic in nature and is easily separated from gangue (unwanted) minerals through magnetic separation processes. Unfortunately, the magnetite ore bodies are diminishing. Because of this, there has been a recent drive to pursue technology that can economically separate hematite (Fe2O3) from its gangue minerals as hematite is a much more abundant source of iron. Most hematite ore has a very small liberation size that is frequently less …

Mechanical Properties Of Graphene Nanoplatelet/Epoxy Composites, Danielle René Klimek-Mcdonald

Dissertations, Master's Theses and Master's Reports - Open

Due to their high specific stiffness, carbon-filled polymer composites are commonly used in the construction of structural components of subsonic fixed-wing aircrafts, such as the fuselage and control surfaces. In this work, neat epoxy (EPON 862 with EPIKURE Curing Agent W) was fabricated along with 1- 6 wt% of three types of GNP available from XG Sciences Inc. and 1-4 wt% of another type of GNP available from Asbury Carbons added to epoxy. The curing cycle for this epoxy was 121 °C for 2 hours followed by 177 °C for two hours.

GNP are short stacks of individual layers of …

Modeling Of Biomass Torrefaction And Pyrolysis And Its Applications, Jordan L. Klinger

Dissertations, Master's Theses and Master's Reports - Open

Utilizing biomass provides a possible near-term alternative solution for fossil energy dependence in both electricity generation and transportation. Though thermochemical conversion can produce solid/liquid fuels that are compatible in existing infrastructure, detailed scientific chemical and mechanistic understanding are still being developed. In contribution to these efforts, this work is focused on development of a semiempirical, lumped parameter, chemical kinetic model to describe the degradation of woody biomass.

The initial kinetic model was developed in the torrefaction region to describe the gas-phase evolution of products (water, organic acids, permanent gases, and furfural) through a three consecutive reaction model. In this model, …

Mechanistic Models On Enzymatic Hydrolysis And Anaerobic Digestion, Yang Zhang

Dissertations, Master's Theses and Master's Reports

For enzymatic hydrolysis, a mechanistic model on enzymatic hydrolysis of pure cellulosic substrates was improved to consider oligomer reactions with beta-glucanases, inhibition of oligomers to cellulases and enzyme decay. Then a novel and general modeling framework was developed for enzymatic hydrolysis of hemicellulose-cellulosic substrates. This mechanistic model, for the first time, took into consideration explicitly the time evolution of morphologies of intertwining cellulose and hemicelluloses. This novel mechanistic model was applied to optimize the composition of enzyme mixtures for substrate conversion and monosaccharides yield during simultaneous enzymatic hydrolysis of different lignocellulosic substrates. For anaerobic digestion, the original "Anaerobic Digestion Model …

Synthesis Of Carbon Nitrides From Carbon Dioxide, Yun Hang Hu

Michigan Tech Patents

Provided are methods of converting carbon dioxide to carbon nitrides. In a first reaction, carbon dioxide may be reacted with metal nitrides, such as Li.sub.3N, to form carbon nitrides in a fast and exothermic reaction. Also provided are methods of using product metal cyanamides from the first reaction to subsequently generate additional carbon nitrides.

Economic Profitability Of The Bakken, North Dakota Unconventional Oil Plays Based On A Typical Well Performance With Current Market Conditions, Mehmet Apaydin

Dissertations, Master's Theses and Master's Reports - Open

Increases in oil prices after the economic recession have been surprising for domestic oil production in the United States since the beginning of 2009. Not only did the conventional oil extraction increase, but unconventional oil production and exploration also improved greatly with the favorable economic conditions. This favorable economy encourages companies to invest in new reservoirs and technological developments. Recently, enhanced drilling techniques including hydraulic fracturing and horizontal drilling have been supporting the domestic economy by way of unconventional shale and tight oil from various U.S. locations. One of the main contributors to this oil boom is the unconventional oil …

Virus Purification, Detection And Removal, Khrupa Saagar Vijayaragavan

Dissertations, Master's Theses and Master's Reports - Open

The biopharmaceutical industry has a growing demand and an increasing need to improve the current virus purification technologies, especially as more and more vaccines are produced from cell-culture derived virus particles. Downstream purification strategies can be expensive and account for 70% of the overall manufacturing costs. The economic pressure and purification processes can be particularly challenging when the virus to be purified is small, as in our model virus, porcine parvovirus (PPV). Our efforts are focused on designing an easy, economical, scalable and efficient system for virus purification, and we focused on aqueous two-phase systems. Industry acceptable standards for virus …

Utilizing Dielectrophoresis To Determine The Physiological Differences Of Eukaryotic Cells, Tayloria Nicole Gail Adams

Dissertations, Master's Theses and Master's Reports - Open

Type 1 diabetes affects over 108,000 children, and this number is steadily increasing. Current insulin therapies help manage the disease but are not a cure. Over a child’s lifetime they can develop kidney disease, blindness, cardiovascular disease and many other issues due to the complications of type 1 diabetes. This autoimmune disease destroys beta cells located in the pancreas, which are used to regulate glucose levels in the body. Because there is no cure and many children are affected by the disease there is a need for alternative therapeutic options that can lead to a cure.

Human mesenchymal stem cells …

Design And Synthesis Of Multifunctional Polymeric Micelles For Gene-Directed Enzyme Prodrug Therapy, Alicia J. Sawdon

Dissertations, Master's Theses and Master's Reports - Open

Gene-directed enzyme prodrug therapy is a form of cancer therapy in which delivery of a gene that encodes an enzyme is able to convert a prodrug, a pharmacologically inactive molecule, into a potent cytotoxin. Currently delivery of gene and prodrug is a two-step process. Here, we propose a one-step method using polymer nanocarriers to deliver prodrug, gene and cytotoxic drug simultaneously to malignant cells. Prodrugs acyclovir, ganciclovir and 5-doxifluridine were used to directly to initiate ring-opening polymerization of epsilon-caprolactone, forming a hydrophobic prodrug-tagged poly(epsilon-caprolactone) which was further grafted with hydrophilic polymers (methoxy poly(ethylene glycol), chitosan or polyethylenemine) to form amphiphilic …

Electrocatalytic Processing Of Renewable Biomass-Derived Compounds For Production Of Chemicals, Fuels And Electricity, Le Xin

Dissertations, Master's Theses and Master's Reports - Open

The dual problems of sustaining the fast growth of human society and preserving the environment for future generations urge us to shift our focus from exploiting fossil oils to researching and developing more affordable, reliable and clean energy sources. Human beings had a long history that depended on meeting our energy demands with plant biomass, and the modern biorefinery technologies realize the effective conversion of biomass to production of transportation fuels, bulk and fine chemicals so to alleviate our reliance on fossil fuel resources of declining supply. With the aim of replacing as much non-renewable carbon from fossil oils with …

Time Lapse Seismic Observations And Effects Of Reservoir Compressibility At Teal South Oil Field, Nayyer Islam

Dissertations, Master's Theses and Master's Reports - Open

One of the original ocean-bottom time-lapse seismic studies was performed at the Teal South oil field in the Gulf of Mexico during the late 1990’s. This work reexamines some aspects of previous work using modern analysis techniques to provide improved quantitative interpretations. Using three-dimensional volume visualization of legacy data and the two phases of post-production time-lapse data, I provide additional insight into the fluid migration pathways and the pressure communication between different reservoirs, separated by faults. This work supports a conclusion from previous studies that production from one reservoir caused regional pressure decline that in turn resulted in liberation of …

Factors Influencing Material Loss During Iron Ore Pellet Handling, Joseph A. Halt

Dissertations, Master's Theses and Master's Reports - Open

Iron ore concentrate pellets have the potential to fracture and abrade during transportation and handling, which produces unwanted fine particulates and dust. Consequently, pellet producers characterize the abrasion resistance of their pellets, using an Abrasion Index (AI), to indicate whether their products will produce unacceptable levels of fines. However, no one has ever investigated whether the AI correlates to pellet dustiness.

During the course of this research, we investigated the relationship between AI and iron ore concentrate pellet dustiness using a wide range of industrial and laboratory pellet samples. The results showed that, in general, AI can be used to …

Life Cycle Assessments (Lcas) Of Pyrolysis-Based Gasoline And Diesel From Different Regional Feedstocks: Corn Stover, Switchgrass, Sugar Cane Bagasse, Waste Wood, Guinea Grass, Algae, And Albizia, Matthew J. Mihalek

Dissertations, Master's Theses and Master's Reports - Open

Renewable hydrocarbon biofuels are being investigated as possible alternatives to conventional liquid transportation fossil fuels like gasoline, kerosene (aviation fuel), and diesel. A diverse range of biomass feedstocks such as corn stover, sugarcane bagasse, switchgrass, waste wood, and algae, are being evaluated as candidates for pyrolysis and catalytic upgrading to produce drop-in hydrocarbon fuels. This research has developed preliminary life cycle assessments (LCA) for each feedstock-specific pathway and compared the greenhouse gas (GHG) emissions of the hydrocarbon biofuels to current fossil fuels. As a comprehensive study, this analysis attempts to account for all of the GHG emissions associated with each …