Biomedical Devices and Instrumentation Commons^™

Edwards Lifesciences - Skirt To Frame Attachment Manufacturing Aid, Samuel Joda, Cesar Grimaldo, Patrick Hutchinson

Mechanical Engineering

No abstract provided.

Stent Graft Blush, Vanessa Barrett, Thomas Matzinger, Mike Morelli

Mechanical Engineering

In order to better understand Type IV endoleaks (“blush”), the Cal Poly Senior Project team GraftTest has developed a blush evaluation system able to mimic several of the aorta’s environmental parameters. Capable of both pressure and flow rate control, this bench top system accommodates Medtronic’s wide range of abdominal and thoracic aortic stent grafts. Having researched endoleaks, stent grafts, and numerous other factors affecting stent graft blush, a system was developed with the aim of assessing and comparing the performance of Medtronic’s stent grafts with regard to blush. Furthermore, this system has been designed to provide reliable and repeatable results …

Design And Development Of A Stair Ascension Assistive Device For Transfemoral Amputees, Casey Michael Barbarino

Master's Theses

Transfemoral amputees around the world experience increased difficulty in climbing stairs due to lack of muscle, balance, and other factors. The loss of a lower limb greatly diminishes the amount of natural force generation provided that is necessary to propel oneself up stairs. This study investigated possible solutions to the problem of stair ascension for transfemoral amputees by the means of designing and developing an externally attachable device to a prosthesis. The number of amputations from military service has greatly increased since 2008, which shows there is a clear need for assistive devices (Wenke, Krueger, & Ficke, 2012). With the …

Design And Testing Of Novel Mouthguard With Intermediate Nitinol And Foam Layers, Adam Kessler

UNLV Theses, Dissertations, Professional Papers, and Capstones

It is the aim of this study to investigate a novel mouthguard design that incorporates the use of a nickel-titanium (Nitinol) layer and thin foam layer in addition to EVA layers. It is thought that the Nitinol layer can distribute the force of an impact and that the thin foam layer may absorb this distributed force better than a solid EVA mouthguard of the same thickness. Rectangular, flat coupons representative of several mouthguard configurations were constructed for testing using an instrumented drop-weight impact tower. The coupon configurations include a control made of laminated EVA, a group of laminated EVA and …

Closed Loop Control Of A Cylindrical Tube Type Ionic Polymer Metal Composite (Ipmc), Benjamin Mead

UNLV Theses, Dissertations, Professional Papers, and Capstones

The goal of this research is to provide a framework for the integration of tube type, cylindrical Ionic Polymer Metal-Composite (IPMC) into conventional devices. IPMCs are one of the most widely used types of electro-active polymer actuator, due to their low electric driving potential and large deformation range. For this research a tube type IPMC was investigated. This IPMC has a circular cross section with four separate electrodes on its surface and a hole through the middle. The four electrodes allow for biaxial bending and accurate control of the tip location. One of the main advantages of using this type …

Novel Approach To Junctional Bleeding: Tourniquet Device Proposal For Battlefield Hemorrhage Control, Kyle W. Cabaniss

Master's Theses

This study investigated possible solutions to the current wartime problem of junctional hemorrhaging, or massive traumatic hemorrhaging in non-tourinquetable areas such as the neck, groin, or armpit. Junctional hemorrhaging has been identified as a major contributor to potentially survivable deaths seen on the battlefield today and therefore is a priority for the U.S. armed and coalition forces (Kragh et al., 2011a; Bozeman, 2011). Common tourniquets today are standard issue and carried by soldiers in the military, but are limited to distal extremity trauma. As the battlefield has changes however, trauma has transformed from commonly seen gunshot wounds to more extreme …

Handitrike - Recumbent Tricycle, Sean Higginson, Kevin Howie, Vinay Patel

Mechanical Engineering

This report covers the design and construction of the recumbent racing tricycle for Mr. Robert T. Kelly, a disabled veteran. Unfortunately Rob’s right leg is five inches shorter than his left one and therefore is unable to properly operate standard cranks. Our team HandiTrike is composed of Sean Higginson, Kevin Howie, and Vinay Patel and our project requires us to come up with a design that is feasible to complete within the given three quarters, as well as allow Rob to gain full use of his tricycle. Currently Rob ‘s trike uses the standard crank set up found on most …

Design, Analysis And Testing Of Haptic Feedback System For Laparoscopic Graspers In In Vivo Surgical Robots, Nikhil Salvi

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Laparo-Endoscopic Single Site (LESS) Robotics Surgery is an advanced technology in the field of Minimally Invasive Surgery (MIS). The LESS surgical robots significantly improve the surgeon’s accuracy, dexterity and visualization, and reduce the invasiveness of surgical procedure results in faster recovery time and improved cosmetic results. In a standard robotic endosurgery, the palpation of tissues is performed by laparoscopic graspers located at the end effectors. The master-slave configuration in robotic surgery leads in remote access to the operation site. Therefore, surgeon’s ability to perceive valuable sensory information is severely diminished. Sensory information such as haptics, which is essential for safe …

Polygrasp: Reach; Myoelectric Prosthetic Hand Iteration, Devon Patrick Augustus, Mighells Blaed Deuel, Ian Noel Fraser, Nicholas Philip Moesser

Mechanical Engineering

Amputations are a common occurrence in soldiers returning home who have suffered the effects of IED and munitions explosions. For upper limb amputees, trans-radial amputations are the most common. Traditional hook devices do not offer an adequate level of normalcy for users, prompting the use of myoelectric devices. While current myoelectric devices do offer a more natural experience, they come with a host of other problems that makes their adoption by service personnel not desirable or not permitted by the VA. PolyGrasp Reach seeks to reduce weight and cost and improve performance. This addresses several of the issues with devices …

Improving Health Care Quality And Safety: The Development And Assessment Of Laparoscopic Surgery Instrumentation, Practices And Procedures, Bernadette Mccrory

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Adverse events due to medical errors are a leading cause of death in the United States exceeding the mortality rates of motor vehicle accidents, breast cancer and AIDS. Improvements can and should be made to reduce the rates of preventable surgical errors since they account for nearly half of all adverse events within hospitals. Although minimally invasive surgery has proven patient benefits such as reduced postoperative pain and hospital stay, its operative environment imposes substantial physical and cognitive strain on the surgeon increasing the risk of error. In order to mitigate errors and protect patients, a multidisciplinary approach was taken …

The Use Of A Pylon Mounted Transducer For Investigating The Gait Of Transtibial Amputees, Justin Robert Brink

UNLV Theses, Dissertations, Professional Papers, and Capstones

Two areas of research interest in the design and use of lower limb prosthetic devices are how foot performance varies with design and how prosthesis alignment affects gait. The current study addressed both of these areas through the use of the JR3 triaxial transducer mounted at the base of the socket. The transducer is an innovative form of instrumentation that measures forces and moments at the end of the socket. Traditional measurement of gait uses a force plate buried in the floor of a gait laboratory. The study established that the transducer offers a viable means of instrumentation for amputee …

Effect Of Extracellular Matrix (Ecm) Protein Micropatterns On The Behavior Of Human Neuroblastoma Cells, Ishwari Poudel

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

Recent advances in patterning techniques and emerging surface microtechnologies have allowed cell micropatterning to control spatial location of the cells on a surface as well as cell shape, attachment area, and number of contacting neighbor cells. These parameters play important roles in cell cellular behaviors. Cell micropatterning has thus become one of the most important strategies for biomedical applications, such as, tissue engineering, diagnostic immunoassays, lab-on-chip devices, bio-sensing, etc., and cell biology studies as well. For neuronal cells, there have been attempts to distribute neuronal cells on specific patterns to control cell-to-cell interaction. However, there have been very limited understanding …

Ros-Drill Automation: Visual Feedback Control And Rotational Motion Tracking, Jhon F. Diaz

Master's Theses

ICSI (intra-cytoplasmic sperm injection) has attracted research interest from both biological and engineering groups. The technology is constantly evolving to perform this procedure with precision and speed. One such development is the contribution of this thesis. We focus on a relatively recent procedure called Ros-Drill^© (rotationally oscillating drill), of which the early versions have already been effectively utilized for the mice. In the first part, we present a procedure to automate a critical part of the operation: initiation of the rotational oscillation, Visual feedback is used to track the pipette tip. Predetermined species-specific penetration depth is successfully utilized …

Control System For Mass Spectrometer, Jian Xu

Purdue Polytechnic Masters Theses

Mass spectrometry (MS) is a very popular analytical methodology that measures the mass of ions using a mass spectrometer. It is widely used for determining masses of chemicals, the elemental composition of a sample and molecule structure. The process of mass spectrometry normally consists of ionizing chemical compounds to ions and measuring their ratios of mass to charge for analysis.

MS instruments consist of three modules: Ionization, Analysis and detection. A LabVIEW system was developed to control the three modules of a mass spectrometer, giving the required signals in a right sequence. Experiments can be carried out by using the …

Gas Embolic Factors In Cardiovascular Health, Eric L. Cutler

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Gas emboli are a clinical issue often encountered in the space exploration, marine construction, and medical fields.  Individuals involved with these disciplines will often have asympomatic gas emboli circulating throughout their bodies on a regular basis.  A study into the impact of chronic asymptomatic gas emboli on the risk of atherosclerosis in humans is thus presented.  This research utilized a custom built cardiovascular flow simulator and accompanying data acquisition system to experimentally determine the influence of gas emboli under varied circumstances on the mean wall shear stress of a tube in-vitro.  A directly inverse relationship between gas embolus presence in …

Intelligibility Of Electrolarynx Speech Using A Novel Hands-Free Actuator, Brian Madden, Mark Nolan, Ted Burke, James Condron, Eugene Coyle

Conference Papers

During voiced speech, the larynx provides quasi-periodic acoustic excitation of the vocal tract. In most electrolarynxes, mechanical vibrations are produced by a linear electromechanical actuator, the armature of which percusses against a metal or plastic plate at a frequency within the range of glottal excitation. In this paper, the intelligibility of speech produced using a novel hands-free actuator is compared to speech produced using a conventional electrolarynx. Two able-bodied speakers (one male, one female) performed a closed response test containing 28 monosyllabic words, once using a conventional electrolarynx and a second time using the novel design. The resulting audio recordings …

Intelligibility Of Electrolarynx Speech Using A Novel Actuator, Brian Madden, Mark Nolan, Ted Burke, James Condron, Eugene Coyle

Conference Papers

During voiced speech, the larynx provides quasi-periodic acoustic excitation of the vocal tract. Following a laryngectomy, some people speak using an electrolarynx which replaces the excitatory function of the absent larynx. Drawbacks of conventional electrolarynx designs include the buzzing monotonic sound emitted, the need for a free hand to operate the device, and difficulty experienced by many laryngectomees in adapting to its use. Despite these shortcomings, it remains the preferred method of speech rehabilitation for a substantial minority of laryngectomees. In most electrolarynxes, mechanical vibrations are produced by a linear electromechanical actuator, the armature of which percusses against a metal …

Towards Supervised Autonomous Task Completion Using An In Vivo Surgical Robot, Jason J. Dumpert

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Laparoscopy is a minimally invasive alternative to traditional abdominal surgery. Unlike traditional surgery, a laparoscopic procedure can be completed using small incisions. The use of these small incision results in reduced pain to the patient, shorter recovery times, and less trauma to skin, muscle and other tissues. However, these benefits to the patient are offset by the increased difficulty to the surgeon performing the procedure. These difficulties include reduced dexterity, reduced perception, and longer procedure times. The use of small in vivo robotic devices in minimally invasive surgery is one possible solution to these problems. The movement of these devices …

An Analysis Of The Performance Of Foams Used In Hurling Helmets, Keith Norris, Stephen Tiernan

Conference Papers

Abstract Head injuries can occur in most sporting activities. The seriousness of these injuries can vary greatly depending on the sport. Many sports such as American football, cricket, baseball and hurling try to reduce this risk by designing helmets that are suitable to be worn by the players. The National Standard Authority of Ireland (NSAI) has recently made great strides in this area with the introduction of the first comprehensive standard adopted for the sport I.S. 355:2006, which sets out new testing procedures that all new helmets must meet. The Gaelic Athletic Association (GAA) has also stated its intention to …

Force Measurement And Evaluation For Surgical Cutting Applications: Development Of An Effective Characterisation Testbed, Dean Callaghan

Conference Papers

Sensorized instruments that cater for accurate measurement of the interaction forces (between biological tissue and instrument end-effector) during surgical procedures offer surgeons a greater sense of immersion during minimally invasive robotic surgery (MIRS). There is much ongoing research into force measurement/evaluation involving surgical graspers. However, comparatively little corresponding effort has been expended in the measurement and subsequent evaluation of forces between scissor blades and tissue. This paper presents the design and development of a force/strain measurement test apparatus, which will ultimately serve as an effective sensor characterisation and evaluation platform. Data acquired from the testing platform can be used to …