Engineering Commons^™

Effects Of Post-Translational Histone Modifications On Transcription Rate, Aaron Bohn

Annual Research Symposium

No abstract provided.

School Personnel Lived Experiences Related To High School Engineering Education And The Covid-19 Pandemic, Justina R. Jackson, Katherine L. Boice, Stephen Cochran, Brooke Skelton, Jeffrey Rosen, Marion Usselman

Journal of Pre-College Engineering Education Research (J-PEER)

This study investigated the teaching experiences of three school personnel at a public high school during the 2020–2021 school year as they implemented a unique science, technology, engineering, arts, and math (STEAM) unit with in-person and virtual students in their engineering classes during the Covid-19 pandemic. A research team interviewed two teachers and one administrator at the school to better understand the nuances of pre-college engineering during a pandemic year and how changes in school and district policy affected the instructional delivery of STEAM projects. Narrative analytic methods were utilized to understand each participant’s experience and an inductive content thematic …

Flight Testing Gls Approaches Enabled By Wide Area Corrections In Kerkyra, Greece, Thomas Dautermann, Thomas Ludwig

Journal of Aviation Technology and Engineering

Many airports with a high value to commercial air traffic have spatial or budgetary constraints which prevent the installation of a precision approach system. We previously designed a low-cost precision approach system which combines the advantages of both ground-based and satellite-based augmentation systems by using a converter between them in order to allow GAST-A approach types. We installed, operated, and flight-tested such a system at Kerkyra Airport using an A320 aircraft. During these, we recorded data from a commercial multimode receiver as well as GPS raw data in order to prove the feasibility of the system. Data were analyzed using …

Development Of A Slow-Degrading Polymerized Curcumin Coating For Intracortical Microelectrodes, Alexis M. Ziemba, Mary Clare Crochiere Woodson, Jessica L. Funnell, Douglas Wich, Bailey Balouch, Deniz Rende, Dahlia N. Amato, Jonathan Bao, Ingrid Oprea, Dominica Cao, Neda Bajalo, Evon S. Ereifej, Jeffrey R. Capadona, Edmund F. Palermo, Ryan J. Gilbert

Chemical and Biochemical Engineering Faculty Research & Creative Works

Intracortical microelectrodes are used with brain-computer interfaces to restore lost limb function following nervous system injury. While promising, recording ability of intracortical microelectrodes diminishes over time due, in part, to neuroinflammation. As curcumin has demonstrated neuroprotection through anti-inflammatory activity, we fabricated a 300 nm-thick intracortical microelectrode coating consisting of a polyurethane copolymer of curcumin and polyethylene glycol (PEG), denoted as poly (curcumin-PEG1000 carbamate) (PCPC). The uniform PCPC coating reduced silicon wafer hardness by two orders of magnitude and readily absorbed water within minutes, demonstrating that the coating is soft and hydrophilic in nature. Using an in vitro release model, curcumin …

Introduction To Bioaerosols Assessment And Control, 2nd Edition, Cheri Marcham, John (Jack) Springston

Publications

• Risk Assessment
• Assessment for the Presence of Bioaerosols
• Sampling
• Purpose/ Necessity
• Interpretation Controls
  • Ventilation
  • Other Controls

Strengthen Building Of Basic Reach Capacity For Semiconductor Research To Light Up “Beacon” Towards Realizing The Self-Reliance And Self-Improvement Of Semiconductors, Junwei Luo, Shushen Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Causes, Countermeasures And Enlightenment Of “Eu Semiconductor Crisis”: Interpretation Around The European Chips Act, Junfeng Li, Ying Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The European Union (EU) is one of the origins of the global semiconductor industry, but due to its structural defects in the semiconductor value chain, it has encountered a crisis of chip shortages and supply cuts since 2021. The European Chips Act drafted by EU proposes a path for semiconductor ecological construction, crisis intervention regulatory measures, and outlines a blueprint for a "national system for the chip industry with EU characteristics". These factors are of speculative significance and reference value for China to balance the relationship between the government and the market, subsidies and competition, key construction and inclusive support …

Analysis On Bottleneck And Prospect Of Integrated Circuit Talent Training Oriented To Sci-Tech Self-Reliance And Self-Strengthening At Higher Levels, Kaixuan Guan, Jiang Yu, Jianzhong Zhou, Feng Chen, Yan Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

The most essential feature of building a new development paradigm is to achieve sci-tech self-reliance and self-strengthening at higher levels. The integrated circuit industry, as an important pillar to achieve this essential feature, is facing a severe external situation. China's chip shortage pain begins with a shortage of talents. The structural problem of uneven development at the overall level of the industry makes it more difficult to effectively gather and distribute talents. To achieve sci-tech self-reliance and self-strengthening at higher levels, we need to be both demand-oriented and problem-oriented, which means not only to pay attention to the core technology …

Modelling And Optimization For An Operating Giant Gas Plant In Egypt, Nessren Farrag, Mohamed Shebl, Mai Fouad, Abdulaziz Abdulaziz

Chemical Engineering

An Egyptian gas-producing plant located in the north of Egypt on the coast of the Mediterranean Sea near Port Said city is designed mainly to receive and treat natural gas produced from offshore wells. The plant designed capacity is around 2800 million standard cubic feet per day (MMSCFD), which gives it a highly appreciated strategic importance. The primary plant process is removing H2S associated with the produced gas using amine solutions. The plant contains seven units called gas trains, which use packed columns for the removal. An additional acid gas removal unit was involved in the early production facility, which …

The Santa Clara, 2023-02-17, Santa Clara University

The Santa Clara

No abstract provided.

A P53-Tlr3 Axis Ameliorates Pulmonary Hypertension By Inducing Bmpr2 Via Irf3, Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan

Chemical and Biochemical Engineering Faculty Research & Creative Works

Pulmonary arterial hypertension (PAH) features pathogenic and abnormal endothelial cells (ECs), and one potential origin is clonal selection. We studied the role of p53 and toll-like receptor 3 (TLR3) in clonal expansion and pulmonary hypertension (PH) via regulation of bone morphogenetic protein (BMPR2) signaling. ECs of PAH patients had reduced p53 expression. EC-specific p53 knockout exaggerated PH, and clonal expansion reduced p53 and TLR3 expression in rat lung CD117+ ECs. Reduced p53 degradation (Nutlin 3a) abolished clonal EC expansion, induced TLR3 and BMPR2, and ameliorated PH. Polyinosinic/polycytidylic acid [Poly(I:C)] increased BMPR2 signaling in ECs via enhanced binding of interferon regulatory …

An Older Diabetes-Induced Mice Model For Studying Skin Wound Healing, Carlos Poblete Jara, Guilherme Nogueira, Joseane Morari, Thaís Paulino Do Prado, Renan De Medeiros Bezerra, Lício A. Velloso, William Velander, Eliana Pereira De Araújo

Department of Chemical and Biomolecular Engineering: Faculty Publications

Advances in wound treatment depend on the availability of animal models that reflect key aspects of human wound healing physiology. To this date, the accepted mouse models do not reflect defects in the healing process for chronic wounds that are associated with type two diabetic skin ulcers. The long term, systemic physiologic stress that occurs in middle aged or older Type 2 diabetes patients is difficult to simulate in preclinical animal model. We have strived to incorporate the essential elements of this stress in a manageable mouse model: long term metabolic stress from obesity to include the effects of middle …

Cognitive Software Defined Networking And Network Function Virtualization And Applications, Sachin Sharma, Avishek Nag

Articles

The emergence of Software-Defined Networking (SDN) and Network Function Virtualization (NFV) has revolutionized the Internet. Using SDN, network devices can be controlled from a centralized, programmable control plane that is decoupled from their data plane, whereas with NFV, network functions (such as network address translation, firewall, and intrusion detection) can be virtualized instead of being implemented on proprietary hardware. In addition, Artificial Intelligence (AI) and Machine Learning (ML) techniques will be key to automating network operations and enhancing customer service. Many of the challenges behind SDN and NFV are currently being investigated in several projects all over the world using …

Importance Of Snowmelt On Soil Nitrate Leaching To Groundwater – A Model Study, Sahila Beegum, Arindam Malakar, Chittaranjan Ray, Daniel D. Snow

Nebraska Water Center: Faculty Publications

The movement of nitrate to surface water bodies during snow accumulation and melting has been extensively studied, but there are only limited studies on the influence of snow processes on nitrate leaching to groundwater. The present study investigated the impact of snow processes on nitrate leaching to groundwater based on a simulation modeling approach using HYDRUS-1D. HYDRUS-1D model has a temperature threshold-based snow model in addition to water, solute, and heat simulation components. The snow component in HYDRUS-1D was previously not applied to snow simulation studies since the method does not consider a detailed physical and process-based representation of snow …

Turbulent Mixing Simulation Using The Hierarchical Parcel-Swapping (Hips) Model, Tommy Starick, Masoomeh Behrang, David O. Lignell, Heiko Schmidt, Alan R. Kerstein

Faculty Publications

Turbulent mixing is an omnipresent phenomenon that permanently affects our everyday life. Mixing processes also
plays an important role in many industrial applications. The full resolution of all relevant flow scales often poses a major challenge to the numerical simulation and requires a modeling of the small-scale effects. In transported Probability Density Function (PDF) methods, the simplified modeling of the molecular mixing is a known weak point. At this place, the Hierarchical Parcel-Swapping (HiPS) model developed by A.R. Kerstein [J. Stat. Phys. 153, 142-161 (2013)] represents a computationally efficient and novel turbulent mixing model. HiPS simulates the effects of turbulence …

Demand Forecasting Method Of Emergency Materials Based On Metabolic Gray Markov, Long Ma, Baodong Qin, Na Lu, Meng Kou

Journal of System Simulation

Abstract: In order to improve the prediction accuracy of the demand for emergency materials of people affected by the disaster, a forecasting method based on metabolism-gray Markov's is proposed. To realize the dynamic prediction of the number of people affected by the disaster, according to demand forecast ideas, the prediction model of metabolism-gray Markov fused is constructed progressively through gray, Markov and metabolism theories. A flexible demand forecasting model for emergency supplies is built through safety stock theory to complete the balance of supply and demand between people number and the materials demand. The prediction results of different …

Se(3)-Based Finite-Time Fault-Tolerant Control Of Spacecraft Integrated Attitude-Orbit, Yafei Mei, Ying Liao, Kejie Gong, Xingyu Zheng

Journal of System Simulation

Abstract: For relative motion spacecraft, when the actuator fails and the external disturbance and system uncertainty occur simultaneously, a finite-time fault-tolerant control method is proposed on the basis of the robustness of sliding mode control. A single-rigid spacecraft integrated attitude-orbit model is established based on Lie Group SE(3), and the relative motion spacecraft error dynamic equation is derived in exponential coordinates. A class of non-singular fast terminal sliding surface is designed, and the equivalent adaptive method is adopted to design the controller to estimate and compensate the total disturbance. The proposed fault-tolerant control algorithm can be independent from fault diagnosis …

Research On Image Super-Resolution Reconstruction Based On Loss Extraction Feedback Attention Network, Hong Sun, Yuxiang Zhang, Yuelan Ling

Journal of System Simulation

Abstract: Since the first application of convolutional neural network to the field of super-resolution image reconstruction (super-resolution convolutional neural network, SRCNN), a large number of studies have proved that deep learning can improve the effect of image reconstruction. Aiming at the too many parameters in the image super-resolution network and the insufficient utilization of image features resulting in less available high-frequency information, a loss extraction feedback attention network (LEFAN) is proposed to reuse parameters in a circular way and increase the reuse of low-resolution image features to capture more high-frequency information. The loss caused in the reconstruction process is extracted …

Research On Cooperative Path Planning Model Of Multiple Unmanned Vehicles In Real Environment, Guohui Zhang, Xuan Wang, Yanan Zhang, Ang Gao

Journal of System Simulation

Abstract: The cluster combat application of unmanned ground vehicles(UVS) is a hot research issue of the intersection of artificial intelligence and battle command. Aiming at the cooperative path planning multiple unmanned vehicles not meeting the dynamic threat condition requirement, by combining the global path planning algorithm A-STAR with the local path planning algorithm RL, from the perspective of perception to behavioral decision making, the cooperative path planning model of multiple unmanned vehicles is studied. The cooperative combat situation threat algorithm, state and action space, reward function and sphere of influence function are designed, the sub-models of formation configuration strategy generation …

Dqn-Based Joint Scheduling Method Of Heterogeneous Tt&C Resources, Naiyang Xue, Dan Ding, Yutong Jia, Zhiqiang Wang, Yuan Liu

Journal of System Simulation

Abstract: Joint scheduling of heterogeneous TT&C resources as research object, a deep Q network (DQN) algorithm based on reinforcement learning is proposed. The characteristics of the joint scheduling problem of heterogeneous TT&C resources being fully analyzied and mathematical language being used to describe the constraints affecting the solution, a resource joint scheduling model is established. From the perspective of applying reinforcement learning, two neural networks with the same structure and the action selection strategies based onεgreedy algorithm are respectively designed after Markov decision process description, and DQN solution framework is established. The simulation results show that DQN-based heterogeneous …

Hardware-In-The-Loop Simulation Platform Of Loop Control For Municipal Solid Waste Incineration Process, Tianzheng Wang, Jian Tang, Heng Xia, Junfei Qiao

Journal of System Simulation

Abstract: To accurately simulate and realize the multiple input multiple output (MIMO) loop control of municipal solid waste incineration (MSWI) process, a distributed hardware-in-the-loop simulation platform consisting of a real device layer and a virtual object layer is developed based on the actual industrial process. The mechanism model is qualitatively described, and a data-driven virtual process object model in terms of loop control is established. The software subsystems of the platform and their cooperative operation mode are designed based on the control requirement. The hardware and software of the proposed platform are built and experimentally verified based on actual industrial …

A Simulation Method Of Airborne Radar Real-Time Detection Based On Three-Dimensional Subdivision, Ying Xu, Shuai Zhang, Zhige Xie, Xinhai Xu, Manhui Sun, Ning Guo

Journal of System Simulation

Abstract: The emergence and rapid development of UAVs make the target detection of UAV airborne radar in combat simulation great research valuable. In the existing combat simulation platforms at home and abroad, the detection relationship between radar and target is pairwise interactive, and the calculation overhead increases linearly or ultra-linear following the increase of entity numbers, which is difficult to carry out the large-scale real-time combat simulation. Based on the concept of three-dimensional meshing, an airborne radar target detection simulation method is proposed, which can quickly judge the success or failure of detection by making a detection template before simulation …

Design And Implementation Of Industrial Robot Remote Monitoring System In Cloud Manufacturing, Yongkui Liu, Lin Zhang, Yingfu Liu, Jianyong Feng, Bo Yu, Wenbo Niu

Journal of System Simulation

Abstract: Considering the lack of the existing research on cloud manufacturing monitoring system and the lack of scalability and flexibility of existing remote monitoring system, and taking deep reinforcement learning-based industrial robot intelligent grasping as an application scenario, a micro-service architecture-based remote monitoring system for cloud manufacturing is developed, to carry out the requirement analysis and design of the monitoring system, and the remote monitoring of industrial robot intelligent grasping processes is realized. Test results show that the system can meet the monitoring requirements of resource providers, platform operator(s) and service consumers.

Design Of System Combat Simulation Platform For Complex Electromagnetic Environment, Baiyuan Ding, Fuling Mu, Yunpeng Li, Zhongkuan Chen, Chengyu Liu

Journal of System Simulation

Abstract: War gaming and simulation can be divided into four levels of strategy、campaign、tactics and technique. Existing system combat simulation platforms of campaign and tactics at home and abroad cannot drive the special model of electromagnetic equipment in technique level, resulting in the low fidelity of battlefield complex electromagnetic environment simulation. To solve the problem, flexible analysis modeling and exercise system(FLAMES) model architecture as the reference, based on the simulation engine library of a discrete event system simulator(ADEVS), a flexible operation simulation platform(FOSim) is designed and developed, which integrates three levels of campaign, tactics and technology, supports three levels independence simulation …

Machine Learning-Based Simulation Research Of On-Line Subway Pedestrian Flow Control, Jiajie Shi, Peng Yang, Yannan Pi

Journal of System Simulation

Abstract: In recent years, a large number of digital experiments have been carried out in the field of space launch, such as digital design verification, digital joint training and simulation training, and rocket-ground joint simulation evaluation, all of which involve the space launch information visualization. Through virtual reality technology, system simulation technology, data visualization technology, etc., on the basis of multi-thread, multi-module architecture design idea, and message queue system interaction mode, the space launch visual simulation analysis technology platform with functions of data management, scenario management, calculation management, and script management is constructed. The application cases of visual simulation analysis …

Takeout Distribution Routes Optimization Considering Order Clustering Under Dynamic Demand, Houming Fan, Fushan Xian, Huaiqi Wang

Journal of System Simulation

Abstract: Takeout distribution optimization includes order allocation and route planning. Aiming at dynamic order and rider position change, with the goal of minimizing the overtime order proportion, average delivery time and average travel distance,a two-stage mathematical model is established based on the idea of pre-optimization and dynamic adjustment. In the pre-optimization stage, an improved variable neighborhood search algorithm is designed to obtain the initial distribution scheme. In the dynamic adjustment stage, a periodic optimization strategy is adopted to transform the problem into a virtual distribution center vehicle problem for solution. In each stage,different clustering methods are used to optimize the …

Automatic Dispersion, Defect, Curing, And Thermal Characteristics Determination Of Polymer Composites Using Micro-Scale Infrared Thermography And Machine Learning Algorithm, Md Ashiqur Rahman, Mirza Masfiqur Rahman, Ali Ashraf

Mechanical Engineering Faculty Publications

Infrared thermography is a non-destructive technique that can be exploited in many fields including polymer composite investigation. Based on emissivity and thermal diffusivity variation; components, defects, and curing state of the composite can be identified. However, manual processing of thermal images that may contain significant artifacts, is prone to erroneous component and property determination. In this study, thermal images of different graphite/graphene-based polymer composites fabricated by hand, planetary, and batch mixing techniques were analyzed through an automatic machine learning model. Filler size, shape, and location can be identified in polymer composites and thus, the dispersion of different samples was quantified …

Online Classification Method For Motor Imagery Eeg With Spatial Information, Fengwei Yang, Peng Chen, Kai Xi, Hualin Pu, Xueyin Liu

Journal of System Simulation

Abstract: EEG-based BCI system can help the daily life and rehabilitation training of limb movement disorders patients. Due to the low signal-to-noise ratio and large individual differences of EEG signals, the accuracy and efficiency of EEG feature extraction and classification are not high, which affects the wide application of online BCI system. A CNN with spatial information is proposed for the online classification of MI-EEG signals. The reordered MI-EEG is convolved horizontally and vertically respectively. With the contralateral effect of motor imagery ERD/ERS phenomenon, the spatial information in MI-EEG is fully utilized to achieve the real-time acquisition and classification of …

Simulation Of Occluded Pedestrian Detection Based On Improved Yolo, Nan Xiang, Lu Wang, Chongliu Jia, Yuemou Jian, Xiaoxia Ma

Journal of System Simulation

Abstract: Aiming at the high missed detection rates and low accuracy of existing YOLO for occlusion and multi-scale pedestrian targets, an improved pedestrian detection algorithm is proposed. YOLO backbone is modified to enhance the capabilities of cross-scale feature extraction. To increase thepedestrian feature fusion capabilities of different scales, a spatial pyramid pooling module and two attention mechanisms are introduced at different positions in front of YOLO layers. Aiming at the detection performance degradation due to the extreme complexity of network module and to improve the model training efficiency, the network structure is pruned according to the actual …

Evacuation Dynamics Research Based On Evolutionary Game Theory, Qiaoru Li, Jinxiu Yan, Xiaoyong Tian, Kun Li, Xia Li

Journal of System Simulation

Abstract: In order to study the impact of individual cooperative behavior on the overall pedestrian evacuation efficiency, combined with cellular automata and social force model, the co-evolution of evacuation system dynamics and "cooperative behavior" is studied, and an evacuation dynamics research method based on evolutionary game theory is proposed. The cellular automata model is used as the basic simulation framework, and the social force model is used to represent the psychological repulsion among the practitioners. The evacuation individual strategy is updated through evolutionary game. The simulation results show that when the game gain coefficient exceeds a certain threshold, the …