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2017

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Articles 1801 - 1830 of 8353

Full-Text Articles in Engineering

Improving Wildflower Longevity In Roadside Seeding Areas, Walter Schacht, Jonathan M. Soper, Carol Wienhold Aug 2017

Improving Wildflower Longevity In Roadside Seeding Areas, Walter Schacht, Jonathan M. Soper, Carol Wienhold

Nebraska Department of Transportation: Research Reports

Re-vegetation efforts on bare roadsides of newly-constructed highways are primarily focused on the stabilization of soil to reduce rates of erosion. The Nebraska Department of Transportation (NDOT) seeds roadsides with a diverse mixture of grasses and wildflowers for site stabilization as well as to enhance the visual quality of roadsides. Although grasses dominate roadside plantings in terms of cover and density, wildflowers are largely responsible for the visual enhancement of recently-seeded roadsides. In addition to the visual component, wildflowers provide essential ecological functions on roadsides. Wildflowers improve water and nutrient cycling in the compacted roadside soils by increasing water infiltration …


Relative Multiplicative Extended Kalman Filter For Observable Gps-Denied Navigation, Daniel P. Koch, David O. Wheeler, Randal Beard, Tim Mclain, Kevin M. Brink Aug 2017

Relative Multiplicative Extended Kalman Filter For Observable Gps-Denied Navigation, Daniel P. Koch, David O. Wheeler, Randal Beard, Tim Mclain, Kevin M. Brink

Faculty Publications

This work presents a multiplicative extended Kalman filter for estimating the relative state of a multirotor vehicle operating in a GPS-denied environment. The filter fuses data from an inertial measurement unit and altimeter with relative-pose updates from a keyframe-based visual odometry or laser scan-matching algorithm. Because the global position and heading states of the vehicle are unobservable in the absence of global measurements such as GPS, the filter in this paper estimates the state with respect to a local frame that is colocated with the odometry keyframe. As a result, the odometry update provides nearly-direct measurements of the relative vehicle …


Relative Navigation Of Autonomous Gps-Degraded Micro Air Vehicles, David O. Wheeler, Daniel P. Koch, James S. Jackson, Gary J. Ellingson, Paul W. Nyholm, Timothy W. Mclain, Randal W. Beard Aug 2017

Relative Navigation Of Autonomous Gps-Degraded Micro Air Vehicles, David O. Wheeler, Daniel P. Koch, James S. Jackson, Gary J. Ellingson, Paul W. Nyholm, Timothy W. Mclain, Randal W. Beard

Faculty Publications

Many current approaches for navigation of micro air vehicles (MAVs) in GPS-degraded environments use a globally-referenced state for estimation and control, even though this state is not observable when GPS is unavailable. By working with respect to a local reference frame, the relative navigation (RN) framework presented in this paper ensures that the state maintains observability and that the uncertainty remains bounded, consistent, and normally-distributed. RN further insulates flight-critical estimation and control processes from the large global updates common in GPS-degraded MAV flight. This paper provides a thorough description of the details needed to successfully implement the RN framework on …


Design And Validation Of Pressure Based Flow Rate Soft Sensor For Freeze-Drying, Pasita Pibulchinda, Tong Zhu, Vaibhav Kshirsagar, Alina A. Alexeenko Aug 2017

Design And Validation Of Pressure Based Flow Rate Soft Sensor For Freeze-Drying, Pasita Pibulchinda, Tong Zhu, Vaibhav Kshirsagar, Alina A. Alexeenko

The Summer Undergraduate Research Fellowship (SURF) Symposium

Lyophilization or freeze drying is a process of removing water by sublimation. It is commonly used to extend the shelf life of drugs in the pharmaceutical industry. Because the process is costly and time consuming, precise and efficient pressure, temperature control and drying time estimation are required. It is the goal of freeze-drying to run at maximum capacity while staying within the safe zone by carefully controlling the sublimation rate. Currently, real time estimation of sublimation rate is still challenging. The technique available called Tunable diode laser absorption spectroscopy (TDLAS) is invasive, and requires major modifications. The current study focuses …


Parallel Computation Using Mems Oscillator-Based Computing System, Xinrui Wang, Ilias Bilionis, Salar Safarkhani Aug 2017

Parallel Computation Using Mems Oscillator-Based Computing System, Xinrui Wang, Ilias Bilionis, Salar Safarkhani

The Summer Undergraduate Research Fellowship (SURF) Symposium

In recent years, parallel computing systems such as artificial neural networks (ANNs) have been of great interest. In these systems which emulate the behavior of human brains, the processing is carried out simultaneously. However, it is still a challenging engineering problem to design highly efficient hardware for parallel computing systems. We will study the properties of networks of Microelectromechanical System (MEMS) oscillators to explore their capabilities as parallel computing infrastructure. Furthermore, we simulate the time-variant states of MEMS oscillators network under various initial conditions and performance of certain tasks. Recent theoretical results show that networks of MEMS oscillators have some …


Interplay Of Quantum Size Effect, Anisotropy And Surface Stress Shapes The Instability Of Thin Metal Films, Mikhail Khenner Aug 2017

Interplay Of Quantum Size Effect, Anisotropy And Surface Stress Shapes The Instability Of Thin Metal Films, Mikhail Khenner

Mathematics Faculty Publications

Morphological instability of a planar surface ([111], [011], or [001]) of an ultra-thin metal film is studied in a parameter space formed by three major effects (the quantum size effect, the surface energy anisotropy and the surface stress) that influence a film dewetting. The analysis is based on the extended Mullins equation, where the effects are cast as functions of the film thickness. The formulation of the quantum size effect (Z. Zhang et al., PRL 80, 5381 (1998)) includes the oscillation of the surface energy with thickness caused by electrons confinement. By systematically comparing the effects, their contributions into the …


Process Considerations For Protein A Affinity Capture, Virus Inactivation, And Linked Polishing Steps In Multi-Column Continuous Purification Of Monoclonal Antibodies, Robert Mierendorf, Tom Van Oosbree, Anthony Grabski, William Wessel, Emily Schirmer Aug 2017

Process Considerations For Protein A Affinity Capture, Virus Inactivation, And Linked Polishing Steps In Multi-Column Continuous Purification Of Monoclonal Antibodies, Robert Mierendorf, Tom Van Oosbree, Anthony Grabski, William Wessel, Emily Schirmer

Integrated Continuous Biomanufacturing III

Multi-column continuous chromatography (MCC) offers significant economic advantages over traditional batch methods for purification of monoclonal antibodies (mAbs), including increased resin capacity utilization, smaller columns, reduced buffer consumption, and faster process time. The Protein A capture step is a primary target to apply MCC due to its high cost, which is driven even higher as improvements in upstream processing have produced a steady increase in mAb titers. In this study we consider the key factors in designing an MCC process that optimizes productivity. Process design begins with determination of the feed duration, which is governed by the mAb titer, column …


A Novel Device For Mr Foot Perfusion Stress Testing, David John Muccigrosso Aug 2017

A Novel Device For Mr Foot Perfusion Stress Testing, David John Muccigrosso

McKelvey School of Engineering Graduate Student Theses & Dissertations

No abstract provided.


Performance Assessment Of Diffuse Optical Spectroscopic Imaging Instruments In A 2-Year Multicenter Breast Cancer Trial, Anais Leproux, Thomas D.O. Sullivan, Albert E. Cerussi, Amanda Durkin, Brian Hill, Nola M. Hylton, Arjun G. Yodh, Stefan A. Carp, David A. Boas, Shudong Jiang, Keith D. Paulsen, Brian W. Pogue, Darren M. Roblyr, Wei T. Yang, Bruce J. Tromberg Aug 2017

Performance Assessment Of Diffuse Optical Spectroscopic Imaging Instruments In A 2-Year Multicenter Breast Cancer Trial, Anais Leproux, Thomas D.O. Sullivan, Albert E. Cerussi, Amanda Durkin, Brian Hill, Nola M. Hylton, Arjun G. Yodh, Stefan A. Carp, David A. Boas, Shudong Jiang, Keith D. Paulsen, Brian W. Pogue, Darren M. Roblyr, Wei T. Yang, Bruce J. Tromberg

Dartmouth Scholarship

We present a framework for characterizing the performance of an experimental imaging technology, diffuse optical spectroscopic imaging (DOSI), in a 2-year multicenter American College of Radiology Imaging Network (ACRIN) breast cancer study (ACRIN-6691). DOSI instruments combine broadband frequency-domain photon migration with time-independent near-infrared (650 to 1000 nm) spectroscopy to measure tissue absorption and reduced scattering spectra and tissue hemoglobin, water, and lipid composition. The goal of ACRIN-6691 was to test the effectiveness of optically derived imaging endpoints in predicting the final pathologic response of neoadjuvant chemotherapy (NAC). Sixty patients were enrolled over a 2-year period at participating sites and received …


Multiphysics Simulation Of Low-Amplitude Acoustic Wave Detection By Piezoelectric Wafer Active Sensors Validated By In-Situ Ae-Fatigue Experiment, Yeasin Bhuiyan, Victor Giurgiutiu Aug 2017

Multiphysics Simulation Of Low-Amplitude Acoustic Wave Detection By Piezoelectric Wafer Active Sensors Validated By In-Situ Ae-Fatigue Experiment, Yeasin Bhuiyan, Victor Giurgiutiu

Faculty Publications

Piezoelectric wafer active sensors (PWAS) are commonly used for detecting Lamb waves for structural health monitoring application. However, in most applications of active sensing, the signals are of high-amplitude and easy to detect. In this article, we have shown a new avenue of using the PWAS transducer for detecting the low-amplitude fatigue-crack related acoustic emission (AE) signals. Multiphysics finite element (FE) simulations were performed with two PWAS transducers bonded to the structure. Various configurations of the sensors were studied by using the simulations. One PWAS was placed near to the fatigue-crack and the other one was placed at a certain …


Jme 4110 Final Design Report - Plant Growth Chamber, Deontez Myers, Chad Szwargulski Aug 2017

Jme 4110 Final Design Report - Plant Growth Chamber, Deontez Myers, Chad Szwargulski

Washington University / UMSL Mechanical Engineering Design Project JME 4110

To facilitate study of resource use efficiency in crop plants, it is necessary to pulse-saturate them with certain stable isotopes. This is done by exposing the shoots to gases and the roots to liquid. We were tasked with designing a system to deliver and control this process.


Jme 4110 Seed Cross-Breeze Distance Tester, Ty Krewson, John Jensen, Emily Dahlberg Aug 2017

Jme 4110 Seed Cross-Breeze Distance Tester, Ty Krewson, John Jensen, Emily Dahlberg

Washington University / UMSL Mechanical Engineering Design Project JME 4110

Because seeds vary in shape, size, and weight, their behaviors in cross-breezes vary as well. The customer’s laboratory is researching seeds for prairie grasses. Their laboratory currently has data for seed structures; however, data for seed dispersion is needed to provide a better correlation to known environmental and genetic factors such as precipitation and DNA changes. The Seed Cross-Breeze Distance Tester is a controlled chamber designed to test the distance a seed will travel in a user-specified windspeed.


Development And Validation For A Mobile Speech-In-Noise Audiometric Task, Tommy Peng Aug 2017

Development And Validation For A Mobile Speech-In-Noise Audiometric Task, Tommy Peng

McKelvey School of Engineering Graduate Student Theses & Dissertations

Traditional speech-in-noise hearing tests are performed by clinicians with specialized equipment. Furthermore, these tasks often present contextually weak sentences in background babble, which are poor representations of real-world situations. This study proposes a mobile audiometric task, Semantic Auditory Search, which uses the Android platform to bypass the need for specialized equipment and presents multiple tasks of two competing real-world conversations to estimate the user’s speech-in-noise hearing ability. Through linear regression models built from data of seventy-nine subjects, three Semantic Auditory Search metrics have been shown to have statistically significant (p < 0.05) with medium effects sizes for predicting QuickSIN SNR50. The internal consistency of the task was also high, with a Cronbach’s alpha of 0.88 or more across multiple metrics. In conclusion, this preliminary study suggests that Semantic Auditory Search can accurately and reliably perform as an automated speech-in-noise hearing test. It also has tremendous potential for extension into automated tests of cognitive function, as well.


Learning Extreme Verification Latency Quickly With Importance Weighting: Fast Compose & Level_Iw, Muhammad Umer Aug 2017

Learning Extreme Verification Latency Quickly With Importance Weighting: Fast Compose & Level_Iw, Muhammad Umer

Theses and Dissertations

One of the more challenging real-world problems in computational intelligence is to learn from non-stationary streaming data, also known as concept drift. Perhaps even a more challenging version of this scenario is when -- following a small set of initial labeled data -- the data stream consists of unlabeled data only. Such a scenario is typically referred to as learning in initially labeled nonstationary environment, or simply as extreme verification latency (EVL). This thesis introduces two different algorithms to operate in this domain. One of these algorithms is a simple modification of our prior work, COMPOSE (COMPacted Object Sample Extraction), …


Single-Step, Atmospheric Pressure Chemical Vapor Deposition Of Methylammonium Bismuth Iodide Thin Films, Xiao Chen Aug 2017

Single-Step, Atmospheric Pressure Chemical Vapor Deposition Of Methylammonium Bismuth Iodide Thin Films, Xiao Chen

McKelvey School of Engineering Graduate Student Theses & Dissertations

Lead halide perovskites (CH3NH3PbI3 and its variants) are promising solar cell absorber materials. Though the reported power conversion efficiencies of lead halide perovskite solar cells (up to 21%) are competitive with commercial silicon solar cells, lead toxicity in these perovskites present a challenge to further scale-up and eventual commercialization. Recently, bismuth (Bi3+) based organic halide perovskite has drawn attention as a substitution for lead-free perovskites, since it is a non-toxic 6p-block element, isoelectronic with Pb2+. Methylammonium bismuth iodide ((CH3NH3)3Bi2I9) is reported …


Cfd Performance Of Turbulence Models For Flow From Supersonic Nozzle Exhausts, Han Ju Lee Aug 2017

Cfd Performance Of Turbulence Models For Flow From Supersonic Nozzle Exhausts, Han Ju Lee

McKelvey School of Engineering Graduate Student Theses & Dissertations

The goal of this thesis is to compare the performance of several eddy-viscosity turbulence models for computing supersonic nozzle exhaust flows. These flows are of relevance in the development of future supersonic transport airplane. Flow simulations of exhaust flows from three supersonic nozzles are computed using ANSYS Fluent. Simulation results are compared to experimental data to assess the performance of various one- and two-equation turbulence models for accurately predicting the supersonic plume flow. One particular turbulence model of interest is the Wray-Agarwal (WA) turbulence model. This is a neat model which has demonstrated promising results mimicking the strength of two …


Effects Of Flexible Substrates On The Performance Of Wearable Antennas, Ahmed Salam Kashkool Aug 2017

Effects Of Flexible Substrates On The Performance Of Wearable Antennas, Ahmed Salam Kashkool

Theses and Dissertations

Due to market trends and rapid development in the wireless technology, wearable devices are expected to become part of our daily life like Google Glass, health monitors, smart watches and so on. The electronics market has oriented toward portable and fancy flexible devices due to their invisibility, outstanding view and disposability. The past decade witnessed an extensive research focused on the development and optimisation of flexible displays. Flexible displays are considered as an appealing and promising technology due to their low profile, low cost, light weight, and portability. Wearable displays deemed as a promising technology applicable to a wide spectrum …


Jme 4110 Phenode Camera Arm Design Project, Kelsey M. Wortmann, Paul Masnica, Matthias Sommer Aug 2017

Jme 4110 Phenode Camera Arm Design Project, Kelsey M. Wortmann, Paul Masnica, Matthias Sommer

Washington University / UMSL Mechanical Engineering Design Project JME 4110

The goal of this design project was to create an extendable camera arm capable of attaching to the shell of the PheNode in-field apparatus created by researchers at the Donald Danforth Plant Science Center. The camera arm extends 36 inches in length, can rotate 180 degrees, and successfully holds a camera for plant imaging with minimal vibrations. We have designed an affordable camera arm that is stable and meets the design parameters given. Our design process is documented in the following report.


Jme 4110 Seed Aerodynamics, Kristin Gonzalez, Vladimir Sidorov Aug 2017

Jme 4110 Seed Aerodynamics, Kristin Gonzalez, Vladimir Sidorov

Washington University / UMSL Mechanical Engineering Design Project JME 4110

This is a report discussing the analysis and results of a wind tunnel that was created to find the terminal velocity of a variety of seeds.


Past, Present And Future Of Surgical Meshes: A Review, Karen Baylón, Perla Rodríguez-Camarillo, Alex Elías-Zúñiga, Jose Antonio Díaz-Elizondo, Robert Gilkerson, Karen Lozano Aug 2017

Past, Present And Future Of Surgical Meshes: A Review, Karen Baylón, Perla Rodríguez-Camarillo, Alex Elías-Zúñiga, Jose Antonio Díaz-Elizondo, Robert Gilkerson, Karen Lozano

Mechanical Engineering Faculty Publications

Surgical meshes, in particular those used to repair hernias, have been in use since 1891. Since then, research in the area has expanded, given the vast number of post-surgery complications such as infection, fibrosis, adhesions, mesh rejection, and hernia recurrence. Researchers have focused on the analysis and implementation of a wide range of materials: meshes with different fiber size and porosity, a variety of manufacturing methods, and certainly a variety of surgical and implantation procedures. Currently, surface modification methods and development of nanofiber based systems are actively being explored as areas of opportunity to retain material strength and increase biocompatibility …


Effects Of Graphical Weather Information Versus Textual Weather Information On Situation Awareness In Meteorology, Stefan Melendez M.S.A., Andrew Dattel Ph.D., Christopher Herbster Ph.D., Debbie Schaum M.A., Andrey Babin Aug 2017

Effects Of Graphical Weather Information Versus Textual Weather Information On Situation Awareness In Meteorology, Stefan Melendez M.S.A., Andrew Dattel Ph.D., Christopher Herbster Ph.D., Debbie Schaum M.A., Andrey Babin

National Training Aircraft Symposium (NTAS)

Prior to a flight, pilots gather meteorological information in order to assess the weather conditions pertaining to their flight and to make decisions based on it. This information can come in various formats, such as text and graphical weather information. Research has shown that people have varying learning preferences and that most people prefer visual learning to verbal learning (i.e., graphical over text). It is hypothesized that this difference in learning preference can affect the way pilots interpret and apply the information they obtain prior to their flight. The researcher hypothesizes that graphical weather information has a greater, more positive …


Improving Instructor Quality Using The Conversation Analytic Role-Play Method (Carm), William A. Tuccio Ph.D. Aug 2017

Improving Instructor Quality Using The Conversation Analytic Role-Play Method (Carm), William A. Tuccio Ph.D.

National Training Aircraft Symposium (NTAS)

The audience will learn about Stokoe’s Conversation Analytic Role-play Method (CARM) (http://www.carmtraining.org) and how it has been used to study and improve talk-in-interaction in professional settings. CARM is a proven, research-based methodology which collects large volumes of recorded audio and/or video particular to a professional setting and then uses detailed transcription and conversation analysis to identify systematic patterns of interaction and problems thereof. Actual excerpts from the dataset are appropriately anonymized and used by facilitators in a workshop setting to create authentic role-play.

The presentation will explain how CARM has been applied to help improve flight instructor teaching …


An Alternative Method Of Identification Of A Failed Engine In Twin-Engine Turboprop Aircraft, Andrey Babin, Andrew R. Dattel Ph.D. Aug 2017

An Alternative Method Of Identification Of A Failed Engine In Twin-Engine Turboprop Aircraft, Andrey Babin, Andrew R. Dattel Ph.D.

National Training Aircraft Symposium (NTAS)

Previous incidents and accidents involving twin-engine aircraft, including the recent TransAsia Flight 235 crash, have revealed that pilots are prone to mistakes in identifying the engine that fails, and subsequently, shutting down the wrong engine, i.e. perfectly working engine. Most accidents of this type happen on takeoff when pilot workload is at its highest level. It may be that the current training procedure for engine failures on takeoff, called identify-verify-feather (IVF), is counterintuitive and may lead to greater confusion. IVF is based on haptic sensory channel, which is known to be less effective than visual channel. This study proposes a …


Jme 4110- Solar Panel Tracker, Bob Stretch, James Eimer, Patrick Kraus Aug 2017

Jme 4110- Solar Panel Tracker, Bob Stretch, James Eimer, Patrick Kraus

Washington University / UMSL Mechanical Engineering Design Project JME 4110

Our design is a passive solar panel tracker using fundamentals of thermodynamics. A fixed solar tracker only operates at peak efficiency for a short period during the day. Our tracker uses the sun's energy to power pistons that push the panel to face the sun throughout the day, increasing efficiency.


Open Source 3d Printers: An Appropriate Technology For Building Low Cost Optics Labs For The Developing Communities, Jephias Gwamuri, Joshua M. Pearce Aug 2017

Open Source 3d Printers: An Appropriate Technology For Building Low Cost Optics Labs For The Developing Communities, Jephias Gwamuri, Joshua M. Pearce

Department of Materials Science and Engineering Publications

The recent introduction of RepRap (self-replicating rapid prototyper) 3-D printers and the resultant open source technological improvements have resulted in affordable 3-D printing, enabling low-cost distributed manufacturing for individuals. This development and others such as the rise of open source-appropriate technology (OSAT) and solar powered 3-D printing are moving 3-D printing from an industry based technology to one that could be used in the developing world for sustainable development. In this paper, we explore some specific technological improvements and how distributed manufacturing with open-source 3-D printing can be used to provide open-source 3-D printable optics components for developing world communities …


Ozone Interaction With Indoor Building Materials And Hvac Filters, Omed Akber Abbass Aug 2017

Ozone Interaction With Indoor Building Materials And Hvac Filters, Omed Akber Abbass

Dissertations and Theses

As modern life develops, humans spend most of their time inside buildings. Understanding the effects of different building materials that exist indoors on indoor air quality is crucial to ensure comfort, health, and productivity of building occupants. Indoor air quality (IAQ) is an important field of building science that focuses on studying the existence of different compounds indoors. These compounds include: airborne particles such as dust, volatile organic compounds (VOCs) such as carbonyls, reactive gases such as radon, ozone and others. Ozone is a strong oxidant gas that has adverse effects on human health, and is highly reactive with building …


Pilot Supply At The Regional Airlines: Airline Response To The Changing Environment And The Impact On Pilot Hiring, Becky Lutte Aug 2017

Pilot Supply At The Regional Airlines: Airline Response To The Changing Environment And The Impact On Pilot Hiring, Becky Lutte

National Training Aircraft Symposium (NTAS)

Regional airlines facing pilot supply challenges have responded to the rapidly changing environment by increasing pay, adjusting lifestyle factors, and enhancing career pathway opportunities. The purpose of this research is to provide a current view of the status of airline hiring at regional airlines, given the changes in pay and other factors, and to explore the impact of increased pay on the airlines ability to meet hiring goals. Data for analysis was collected through interviews of pilot recruiting personnel from the 10 largest regional airlines. Preliminary results reveal that regional airlines are meeting hiring goals but airlines remain significantly challenged …


Aluminosilicate Dissolution And Silicate Carbonation During Geologic Co2 Sequestration, Yujia Min Aug 2017

Aluminosilicate Dissolution And Silicate Carbonation During Geologic Co2 Sequestration, Yujia Min

McKelvey School of Engineering Graduate Student Theses & Dissertations

Geologic CO2 sequestration (GCS) is considered a promising method to reduce anthropogenic CO2 emission. Assessing the supercritical CO2 (scCO2)¬–gas or liquid phase water (g, l)–mineral interactions is critical to evaluating the viability of GCS processes. This work contributes to our understanding of geochemical reactions at CO2¬–water (g, l)–mineral interfaces, by investigating the dissolution of aluminosilicates in CO2-acidified water (l). Plagioclase and biotite were chosen as model minerals in reservoir rock and caprock, respectively. To elucidate the effects of brine chemistry, first, the influences of cations in brine including Na, Ca, and K, have been investigated. In addition to the cations, …


Development Of High Resolution Tools For Investigating Cardiac Arrhythmia Dynamics, Christopher Reed Gloschat Aug 2017

Development Of High Resolution Tools For Investigating Cardiac Arrhythmia Dynamics, Christopher Reed Gloschat

McKelvey School of Engineering Graduate Student Theses & Dissertations

Every year 300,000 Americans die due to sudden cardiac death. There are many pathologies, acquired and genetic, that can lead to sudden cardiac death. Regardless of the underlying pathology, death is frequently the result of ventricular tachycardia and/or fibrillation (VT/VF). Despite decades of research, the mechanisms of ventricular arrhythmia initiation and maintenance are still incompletely understood.

A contributing factor to this lack of understanding is the limitations of the investigative tools used to study VT/VF. Arrhythmias are organ level phenomena that are governed by cellular interactions and as such, near cellular levels of resolution are needed to tease out their …


Novel Pet Systems And Image Reconstruction With Actively Controlled Geometry, Ke Li Aug 2017

Novel Pet Systems And Image Reconstruction With Actively Controlled Geometry, Ke Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Positron Emission Tomography (PET) provides in vivo measurement of imaging ligands that are labeled with positron emitting radionuclide. Since its invention, most PET scanners have been designed to have a group of gamma ray detectors arranged in a ring geometry, accommodating the whole patient body. Virtual Pinhole PET incorporates higher resolution detectors being placed close to the Region-of-Interest (ROI) within the imaging Field-of-View (FOV) of the whole-body scanner, providing better image resolution and contrast recover. To further adapt this technology to a wider range of diseases, we proposed a second generation of virtual pinhole PET using actively controlled high resolution …