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2013

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Articles 6931 - 6960 of 7289

Full-Text Articles in Engineering

New Approach For Modeling Hybrid Pressure Swing Adsorption-Distillation Processes, Fan Wu Jan 2013

New Approach For Modeling Hybrid Pressure Swing Adsorption-Distillation Processes, Fan Wu

Theses and Dissertations

A new methodology for modeling hybrid pressure swing adsorption (PSA)-distillation processes has been developed. Two hybrid systems were simulated as examples. One is for ethanol dehydration, and the other is for propane/propylene separation. Firstly, a distillation process simulator such as Chemsep was used to simulate the distillation process of the hybrid system, in which the PSA unit was treated as a "black box" with an assumed process performance. In this way, a hybrid PSA-distillation process can be analyzed simply by performing mass balances around these units and running Chemsep to determine the possibility of energy saving compared to a reference …


Effect Of Matrix Modulus On Cancer Stem Cells And Tumorsphere Formation In Three-Dimensional-Engineered Matrix, Samaneh Kamali Sarvestani Jan 2013

Effect Of Matrix Modulus On Cancer Stem Cells And Tumorsphere Formation In Three-Dimensional-Engineered Matrix, Samaneh Kamali Sarvestani

Theses and Dissertations

Maintenance of cancer stem cells (CSCs) is regulated by their microenvironment. As cancer cells are affected by many factors in their microenvironment, a major challenge is to isolate the effect of a specific factor on cancer stem cells (CSCs) while keeping other factors unchanged. We have developed a synthetic inert 3D polyethylene glycol diacrylate (PEGDA) gel culture system as a unique tool to study the effect of microenvironmental factors on CSCs response. Synthetic hydrogels provide the flexibility to design three-dimensional (3D) matrices to isolate and study individual factors in the tumor microenvironment.

The objective of this work was to investigate …


Polyspectral Signal Analysis Techniques For Condition Based Maintenance Of Helicopter Drive-Train System, Mohammed Ahmed Hassan Mohammed Jan 2013

Polyspectral Signal Analysis Techniques For Condition Based Maintenance Of Helicopter Drive-Train System, Mohammed Ahmed Hassan Mohammed

Theses and Dissertations

For an efficient maintenance of a diverse fleet of air- and rotorcraft, effective condition based maintenance (CBM) must be established based on rotating components monitored vibration signals.

In this dissertation, we present theory and applications of polyspectral signal processing techniques for condition monitoring of critical components in the AH-64D helicopter tail rotor drive train system. Currently available vibration-monitoring tools are mostly built around auto- and cross-power spectral analysis which have limited performance in detecting frequency correlations higher than second order. Studying higher order correlations and their Fourier transforms, higher order spectra, provides more information about the vibration signals which helps …


Impedance Estimation Using Randomized Pulse Width Modulation And Power Converters, William M. Mccoy Jan 2013

Impedance Estimation Using Randomized Pulse Width Modulation And Power Converters, William M. Mccoy

Theses and Dissertations

With the adoption of technologies such as alternative energy production, DC power grids, and electric vehicles, the use of high power switching converters has seen a dramatic increase. These power converters serve many rolls such as grid-tied inverters in solar farms, high power charging for electric vehicles, motor drives for industrial applications, and DC links in transmission systems. With the increased prevalence of such devices, it is only natural to attempt to optimize their operation. As with any level of converter, it is desirable to have accurate control over the generated voltages and currents. Often, these controllers implement some form …


Crystal Growth, Characterization And Fabrication Of Cdznte-Based Nuclear Detectors, Ramesh Madhu Krishna Jan 2013

Crystal Growth, Characterization And Fabrication Of Cdznte-Based Nuclear Detectors, Ramesh Madhu Krishna

Theses and Dissertations

In today's world, nuclear radiation is seeing more and more use by humanity as time goes on. Nuclear power plants are being built to supply humanity's energy needs, nuclear medical imaging is becoming more popular for diagnosing cancer and other diseases, and control of weapons-grade nuclear materials is becoming more and more important for national security. All of these needs require high-performance nuclear radiation detectors which can accurately measure the type and amount of radiation being used. However, most current radiation detection materials available commercially require extensive cooling, or simply do not function adequately for high-energy gamma-ray emitting nuclear materials …


High Resistivity Amorphous Selenium Alloy Semiconductors For Radiation Detection Applications, Abhinav Mehta Jan 2013

High Resistivity Amorphous Selenium Alloy Semiconductors For Radiation Detection Applications, Abhinav Mehta

Theses and Dissertations

High resolution noninvasive tools of diagnosis has always derived and enabled scientific and medical research to probe and better understand subtleties of matter, intangible to the human eye. Radiation detection systems are highly dependent on advancements in materials and devices with front-end electronics. There are various discrete applications of these radiation detectors and each application imposes certain requirements so there is no single optimum radiation detector.

Flat panel x-ray imagers have gained high demand in the past decade because of exponential improvement in readout electronics. We have synthesized and investigated stabilized amorphous selenium (a-Se) alloys suitable for high resolution flat …


Iii-V Nitride Micro- And Nano-Scale Cantilevers For Multimodal Sensing Applications, Ehtesham Bin Quddus Jan 2013

Iii-V Nitride Micro- And Nano-Scale Cantilevers For Multimodal Sensing Applications, Ehtesham Bin Quddus

Theses and Dissertations

Recent research trends in chemical and biological sensing have been geared toward developing molecular sensor devices that are fast, label free, miniaturized and portable. The performance of these devices can be dramatically improved by utilizing multimodal detection techniques, new materials and micro-/nanofabrication technologies. This is especially true for micro-/nanoscale cantilever sensors, which undergo changes in mechanical or electrical properties upon the specific binding of molecules. To develop the sensor devices with the above attributes, we utilized III-V nitride materials: InN nanowires for realizing nanoscale cantilevers and AlGaN/GaN heterostuctures with or without embedded HFETs, for developing microcantilevers. There are mainly two …


Wireless Pressure Sensor System For Medical Applications, Xuehe Wang Jan 2013

Wireless Pressure Sensor System For Medical Applications, Xuehe Wang

Theses and Dissertations

Telemedicine in the modern era is a rapidly developing industry. In a telemedicine system, sensor is the key elements and play important role in any telemedicine applications, especially implantable sensors. Unlike traditional in vitro sensors, there are some special requirements for them like battery-less, compact, and bio-friendly. Therefore, many researchers in institutes as well as in industry are continually developing implantable sensor and sensor system to fulfill the requirements of medical applications.Nine in one thousand people in the United States are born with congenital heart defects and sixty percent die before one year old. As a result, it will be …


Stabilizing Controller Design For A Dc Power Distribution System Using A Passivity-Based Stability Criterion, Antonino Riccobono Jan 2013

Stabilizing Controller Design For A Dc Power Distribution System Using A Passivity-Based Stability Criterion, Antonino Riccobono

Theses and Dissertations

In modern times there has been an increased penetration of power electronic converters into Power Distribution Systems. In particular, there has been a strong interest in DC Power Distribution Systems as opposed to conventional AC Power distribution systems. These DC Power Distribution Systems are enabled by power electronics converters. The strong interest is motivated by improvements in power electronic converter technology, like advances in power semiconductor devices, magnetics, control, and converter topologies which have made possible to build high-performance converters at low cost. In many systems, such as cars, ships and airplanes, there has also been a trend towards the …


High Quality Silicon Carbide Epitaxial Growth By Novel Fluorosilane Gas Chemistry For Next Generation High Power Electronics, Tawhid Rana Jan 2013

High Quality Silicon Carbide Epitaxial Growth By Novel Fluorosilane Gas Chemistry For Next Generation High Power Electronics, Tawhid Rana

Theses and Dissertations

High quality, thick (~100µm), low doped and low defect density SiC epitaxial films are essential for high voltage (blocking voltage >10kV), light, compact and reliable next generation power devices. One of the significant challenges in obtaining high quality thick SiC epitaxial films is to restrict/eliminate the Si gas-phase nucleation or aerosol formation during growth. The generated aerosol particles adversely influence growth by reducing the growth rate due to precursor losses, and also affect crystal quality, since the Si droplets are carried to the crystal growth surface. Moreover, liquid aerosol particles adhere to the various reactor parts (parasitic deposition), and contribute …


Experimental And Simulation Predicted Crack Paths For Al-2024-T351 Under Mixed-Mode I/Ii Fatigue Loading Using An Arcan Fixture, Eileen Miller Jan 2013

Experimental And Simulation Predicted Crack Paths For Al-2024-T351 Under Mixed-Mode I/Ii Fatigue Loading Using An Arcan Fixture, Eileen Miller

Theses and Dissertations

Mixed mode I/II fatigue experiments and simulations are performed for an Arcan fixture and a 6.35mm thick Al-2024-T351 specimen. Experiments were performed for Arcan loading angles that gave rise to a range of Mode I/II crack tip conditions from 0 ¡Ü ¦¤KII/¦¤KI ¡Ü ¡Þ. Measurements include the crack paths, loading cycles and maximum and minimum loads for each loading angle. Simulations were performed using three-dimensional finite element analysis (3D-FEA) with 10-noded tetrahedral elements via CRACK3D. While modeling the entire fixture-specimen geometry, a modified version of VCCT with automatic crack tip re-meshing and a maximum normal stress criterion were used to …


Studying On Capacity Fade Mechanisms Of Li-Ion Batteries Through Modeling, Yiling Dai Jan 2013

Studying On Capacity Fade Mechanisms Of Li-Ion Batteries Through Modeling, Yiling Dai

Theses and Dissertations

Li-ion batteries are promising candidates as power sources for hybrid electric/electric vehicles, as well as storage devices for renewable energies (wind, solar). Longer life batteries are more desirable for large-scale application, which would help lower the capital cost ($/KW) and improve the system stability. However, the aging problem of Li-ion batteries obstructs their fast penetration into these markets. The cell life can be improved based on an in-depth understanding of the fade mechanisms. The purpose of this dissertation is to explore, through a mathematical modeling approach, failure mechanisms of Li-ion batteries.

To study the capacity fade of a LiMn2O4 (LMO) …


Development Of High-Throughput Catalyst Screening For Ammonia Based Selective Catalytic Reduction Of Nitric Oxide With Parallel Analysis Using Fourier Transform Infrared Imaging, Shahriar Salim Jan 2013

Development Of High-Throughput Catalyst Screening For Ammonia Based Selective Catalytic Reduction Of Nitric Oxide With Parallel Analysis Using Fourier Transform Infrared Imaging, Shahriar Salim

Theses and Dissertations

Lean-burn engines, which operate under excess air to fuel ratio offer significant fuel efficiency as well as contribute to the reductions of greenhouse gas emissions. However, lean burn engines produce three main pollutants carbon monoxide (CO), nitrogen oxides (NOx) and unburned or partially burned hydrocarbons (HC), which have detrimental effect on both environment and human life. The conventional three way catalyst (TWC) which was designed to reduce NOx under stoichiometric conditions is not effective under lean-burn engine exhaust condition. Recent studies have shown that copper (Cu) exchanged chabazite (CHA) type zeolites are very promising catalysts for urea or ammonia (NH3) …


Structural Health Monitoring Of Concrete Systems, Matthew Kelly Jones Jan 2013

Structural Health Monitoring Of Concrete Systems, Matthew Kelly Jones

Theses and Dissertations

Concrete material is widely used around the world for the construction of many infrastructure including highway bridges, residential and commercial building, dams, electric power generation plants, and nuclear power plants. It is therefore practical to continue development of both improved structural systems as well as innovative condition assessment techniques for new and existing concrete structures. This thesis includes two studies which focus on structural health monitoring of concrete systems. The first project deals with performance assessment of an in-situ precast approach slab system and the second is an investigation of acoustic emission (AE) as a condition assessment technique for alkali-silica …


Efficient Generation Of Power In Medium Voltage Direct Current Systems: Variable Speed Operation And Rectifier Considerations, Dan Li Jan 2013

Efficient Generation Of Power In Medium Voltage Direct Current Systems: Variable Speed Operation And Rectifier Considerations, Dan Li

Theses and Dissertations

By investigating variable speed operation of an engine and different types of ac-dc rectifier topologies, this dissertation provides procedures to develop and implement efficient Medium Voltage Direct Current (MVDC) power systems. The research reported here offered solutions to the following issues:

1) Efficiency improvement of a gas turbine by running it in variable speed operation mode.

2) The advantages and disadvantages of different ac-dc rectifier topologies considering both the efficiency and rectifier performance (dc bus voltage regulation, weight/size/volume of passive components, number of semi-conductor devices, displacement power factor, complexity of control strategy, etc.)

3) Implementation of variable speed MVDC power …


Optimal Design And Control Of Dc-Dc Resonant Converters For Wireless Power Transfer Applications, Isaac Nam Jan 2013

Optimal Design And Control Of Dc-Dc Resonant Converters For Wireless Power Transfer Applications, Isaac Nam

Theses and Dissertations

Wireless power transfer (WPT) technology provides galvanic isolation for improved safety and also provides reliability by eliminating the need for dedicated connectors/adapters that can get damaged due to frequent usage. For these reasons, it has become popular in medical implant charging and electric vehicle (EV) charging. Beyond these niche applications, due to aesthetic features and convenience provided by the cord-free environment, it is rapidly becoming an attractive charging solution for various portable electronics as well as household appliances. However, currently available WPT technology demonstrates several shortcomings and various challenges due to allowed receiver position variation with respect to transmitter position. …


Squeeze Flow Of Highly Concentrated Suspensions, Mohsen Nikkhoo Jan 2013

Squeeze Flow Of Highly Concentrated Suspensions, Mohsen Nikkhoo

Theses and Dissertations

In this thesis we investigated through experiment and model, the anomalous normal stress distribution during constant-force squeeze flow of highly concentrated suspensions. Using pressure-sensitive films the normal stress distribution is measured in suspensions of glass spheres in a Newtonian liquid undergoing constant-force squeeze flow. At volume fractions of solids up to 0.55, the normal stress distribution is independent of volume fraction and almost identical to the parabolic pressure distribution expected for Newtonian fluids. However, at higher volume fractions, the normal stresses become an order of magnitude larger near the center and very low beyond that region. At these high volume …


Numerical Study Of Stable Tearing Crack Growth Events Using The Cohesive Zone Model Approach, Xin Chen Jan 2013

Numerical Study Of Stable Tearing Crack Growth Events Using The Cohesive Zone Model Approach, Xin Chen

Theses and Dissertations

Numerical analysis of stable tearing crack growth events plays an important role in assessing the structural integrity and residual strength of critical engineering structures. The cohesive zone model (CZM) has been widely applied to simulate fracture processes in a variety of material systems. However, its application to the study of elastic-plastic stable tearing crack growth events in ductile materials, especially under mixed-mode loading conditions, has been limited. The current study is aimed at investigating the applicability of the CZM based approach in simulating mixed-mode stable tearing crack growth events in aluminum alloys. In the simulations, which are carried out using …


Structural Origin Of Mechanical Prowess In Conch Shells, Haoze Li Jan 2013

Structural Origin Of Mechanical Prowess In Conch Shells, Haoze Li

Theses and Dissertations

Conch shells are natural nanocomposites with an exquisite multiscale hierarchical architecture which exhibit coupled ultrahigh mechanical strength and toughness. What materials design strategy renders conch shells such mechanical prowess? In this study, micro/nanoscale structural and mechanical characterization of conch shells (Busycon carica) has been carried out. We demonstrate, for the first time, direct evidence that the previously claimed single-crystal third-order lamellae - the basic building blocks in conch shells are essentially assembled with aragonite nanoparticles of the size ranging from 20 to 45 nm. The third-order lamellae exhibit not only elasticity but also plasticity with the strain up to 0.7% …


Synthesis And Characterization Of One Dimensional Boron-Based Nanomaterials, Rui Li Jan 2013

Synthesis And Characterization Of One Dimensional Boron-Based Nanomaterials, Rui Li

Theses and Dissertations

One dimensional (1D) metal borate and boride nanomaterials have attracted tremendous attention due to their good chemical inertness, high-temperature stability, excellent mechanical properties, and low thermal expansion coefficient.

Beta-BaB2O4 (BBO) is a well-known nonlinear optical material with a high second-order nonlinear susceptibility, wide transparency range, and high damage threshold. Using a low temperature, organic-free hydrothermal technique, single-crystalline barium polyborate Ba3B6O9(OH)6 (BBOH) nanorods were synthesized. It was found that BBO nanospindles can be achieved by annealing the BBOH nanorods at a relatively low temperature of 810 oC. Transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) techniques were …


Parsing The Effects Of Physical Microenvironmental Cues On Stem Cell Adhesion And Lineage Specification, Greg M. Harris Jan 2013

Parsing The Effects Of Physical Microenvironmental Cues On Stem Cell Adhesion And Lineage Specification, Greg M. Harris

Theses and Dissertations

Tissue engineering is a broad field geared toward improving or replacing biological material and comprises an immense collection of biological nuances to consider before strategies for clinical applications can be fully realized. Physical and biochemical signals are responsible for making up a cell's microenvironment to guide morphology and function through cell-extracellular matrix signaling, cell-cell signaling, and soluble signaling. In particular, a deeper understanding of these cell-extra cellular matrix factors guiding stem cell adhesion, spreading, and differentiation is crucial to harnessing the potential to develop tissue for regenerative purposes. Mounting evidence suggests that physical cues are a key to understanding the …


Quasinovo: Algorithms For De Novo Peptide Sequencing, James Paul Cleveland Jan 2013

Quasinovo: Algorithms For De Novo Peptide Sequencing, James Paul Cleveland

Theses and Dissertations

High-throughput proteomics analysis involves the rapid identification and characterization of large sets of proteins in complex biological samples. Tandem mass spectrometry (MS/MS) has become the leading approach for the experimental identification of proteins. Accurate analysis of the data produced is a computationally challenging process that relies on a complex understanding of molecular dynamics, signal processing, and pattern classification. In this work we address these modeling and classification problems, and introduce an additional data-driven evolutionary information source into the analysis pipeline.

The particular problem being solved is peptide sequencing via MS/MS. The objective in solving this problem is to decipher the …


The Study Of Alternate, Solid-Phase Fluorinating Agents For Use In Reactive Gas Recycle Of Used Nuclear Fuel, Dillon Inabinett Jan 2013

The Study Of Alternate, Solid-Phase Fluorinating Agents For Use In Reactive Gas Recycle Of Used Nuclear Fuel, Dillon Inabinett

Theses and Dissertations

Surrogate oxides of the Used Nuclear Fuel (UNF) matrix were fluorinated using alternate, solid-phase fluorinating agents XeF2 and NH4HF2 to form volatile and non-volatile compounds and demonstrate the possibility of a chemical and thermal separations. A matrix of experiments was conducted at the milligram quantity scale using a Shimadzu DTG-60 TG/DTA installed at SRNL (Savannah River National Laboratory) for testing of all non-radioactive samples and a Netzsch STA 409 TGA installed in the laboratory at USC (University of South Carolina) for testing of all radioactive samples. The fluorination and subsequent volatilization potentials were analyzed by mixing excess fluorinating agent with …


Osteon-Mimetic Nanocomposite Materials For Bone Regeneration, Ozan Karaman Jan 2013

Osteon-Mimetic Nanocomposite Materials For Bone Regeneration, Ozan Karaman

Theses and Dissertations

The limitations of large bone defect regeneration has brought the focus of Bone Tissue Engineering research on fabricating three-dimensional bone-mimetic grafts that could enhance osteogenesis and vascularization. Osteons composed of apatite-deposited aligned collagen nanofiber layers are the fundamental building blocks of cortical bone. In natural cortical bone, mineralization is mediated by extracellular matrix (ECM) proteins with amino acid sequences rich in glutamic acid. This dissertation is focused on the establishment of a novel biomimetic approach to engineer scaffolds for healing large bone defects.

In the first part, we investigated the effect of calcium phosphate (CaP) deposition on aligned surface-modified nanofibers …


Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles Jan 2013

Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles

Theses and Dissertations

Cell transplantation can be considered a regenerative therapy, an intervention which attempts to replace or restore the function of compromised tissue by harnessing innate properties of cells that cannot be replicated artificially. For such therapies to succeed, it will be necessary to understand and closely match the physiological conditions that govern cell behaviors in vivo. One important factor is low oxygen tension, termed hypoxia, which is often overlooked in vitro. Because oxygen insufficiency can lead to cell death, hypoxia has traditionally been viewed as a negative condition. However, hypoxia can also serve as a potent regulator of crucial cell behaviors …


Supply Chain Optimization Of Blood Products, Serkan Gunpinar Jan 2013

Supply Chain Optimization Of Blood Products, Serkan Gunpinar

USF Tampa Graduate Theses and Dissertations

Major challenges in the management of blood supply chain are related to the shortage and wastage of the blood products. Given the perishability characteristics of blood which can be stored up to a limited number of days, if hospitals and blood centers keep an excessive number of blood units on inventory, wastages may occur. On the other hand, if sufficient number of blood units are not stored on inventory, shortages of this resource may cause the cancellations of important activities and increase the fatality rates at hospitals. Three mathematical models have been developed with the goal to improve the efficiency …


Tpm: Cloud-Based Tele Ptsd Monitor Using Multi-Dimensional Information, Roger Xu, Gang Mei, Guangfan Zhang, Pan Gao, Aaron Pepe, Jiang Li, James D. Westwood (Ed.), Susan W. Westwood (Ed.), Li Felländer-Tsai (Ed.), Randy S. Haluck (Ed.), Richard A. Robb (Ed.), Steven Senger (Ed.), Kirby G. Vosburgh (Ed.) Jan 2013

Tpm: Cloud-Based Tele Ptsd Monitor Using Multi-Dimensional Information, Roger Xu, Gang Mei, Guangfan Zhang, Pan Gao, Aaron Pepe, Jiang Li, James D. Westwood (Ed.), Susan W. Westwood (Ed.), Li Felländer-Tsai (Ed.), Randy S. Haluck (Ed.), Richard A. Robb (Ed.), Steven Senger (Ed.), Kirby G. Vosburgh (Ed.)

Electrical & Computer Engineering Faculty Publications

An automated system that can remotely and non-intrusively screen individuals at high risk for Post-Traumatic Stress Disorder (PTSD) and monitor their progress during treatment would be desired by many Veterans Affairs (VAs) as well as other PTSD treatment and research organizations. In this paper, we present an automated, cloud-based Tele-PTSD Monitor (TPM) system based on the fusion of multiple sources of information. The TPM system can be hosted in a cloud environment and accessed through landline or cell phones, or on the Internet through a web portal or mobile application (app).


Hyperspectral Image Classification Using A Spectral-Spatial Sparse Coding Model, Ender Oguslu, Guoqing Zhou, Jiang Li, Lorenzo Bruzzone (Ed.) Jan 2013

Hyperspectral Image Classification Using A Spectral-Spatial Sparse Coding Model, Ender Oguslu, Guoqing Zhou, Jiang Li, Lorenzo Bruzzone (Ed.)

Electrical & Computer Engineering Faculty Publications

We present a sparse coding based spectral-spatial classification model for hyperspectral image (HSI) datasets. The proposed method consists of an efficient sparse coding method in which the l1/lq regularized multi-class logistic regression technique was utilized to achieve a compact representation of hyperspectral image pixels for land cover classification. We applied the proposed algorithm to a HSI dataset collected at the Kennedy Space Center and compared our algorithm to a recently proposed method, Gaussian process maximum likelihood (GP-ML) classifier. Experimental results show that the proposed method can achieve significantly better performances than the GP-ML classifier when training data …


User-Based Filter Utilization For Multicarrier Schemes, Zekeriyya Esat Ankarali Jan 2013

User-Based Filter Utilization For Multicarrier Schemes, Zekeriyya Esat Ankarali

USF Tampa Graduate Theses and Dissertations

Multicarrier modulation is a transmission technique that is quite convenient for high data rates in wireless communication. Information symbols are partitioned and parallelly sent over multiple narrowband subchannels. Pulse shaping filters are critically important in multicarrier

modulation for determining the characteristics of signal in time and frequency domains. In this thesis, we propose a new pulse shaping approach for multicarrier schemes to increase spectral efficiency in multi-user scenarios. Conventionally, the time-frequency lattice and the prototype filter are designed considering the worst-case of time-varying multipath channel. However, this approach ignores to make use of multi-user diversity and leads to excessive spacings …


Classification Models In Clinical Decision Making, Eleazar Gil-Herrera Jan 2013

Classification Models In Clinical Decision Making, Eleazar Gil-Herrera

USF Tampa Graduate Theses and Dissertations

In this dissertation, we present a collection of manuscripts describing the development of prognostic models designed to assist clinical decision making. This work is motivated by limitations of commonly used techniques to produce accessible prognostic models with easily interpretable and clinically credible results. Such limitations hinder prognostic model widespread utilization in medical practice.

Our methodology is based on Rough Set Theory (RST) as a mathematical tool for clinical data anal- ysis. We focus on developing rule-based prognostic models for end-of life care decision making in an effort to improve the hospice referral process. The development of the prognostic models is …