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Full-Text Articles in Engineering

Human Comfort Modeling, Measurement, And Improvement In Human–Robot Collaboration, Yuchen Yan Aug 2025

Human Comfort Modeling, Measurement, And Improvement In Human–Robot Collaboration, Yuchen Yan

All Dissertations

A dissertation is proposed to explore human comfort in human-robot collaboration (HRC) through modeling, prediction, and enhancement methodologies. Human comfort is a crucial yet underexplored factor in HRC, directly influencing task efficiency, trust, and overall collaboration effectiveness. Understanding the influential factors, developing computational models, and refining methods to improve human comfort in HRC are essential steps toward advancing the field of collaborative robotics. To address these challenges, multiple studies have been conducted. A series of experimental studies were performed to investigate how robot motion-based parameters affect human comfort in HRC. These studies examined both analytical comfort modeling approaches and physiological …


An Investigation Into The Impact Of Inverter Based Resources On Critical Clearing Time, Trupal Patel Aug 2025

An Investigation Into The Impact Of Inverter Based Resources On Critical Clearing Time, Trupal Patel

All Dissertations

Renewable energy sources, mainly inverter-based resources (IBRs) such as solar and wind plants are being connected in large numbers to the bulk power grid in the United States and around the world. Additionally, generation using fossil fuels are being phased out, which results in the loss of rotor inertia, a key contributor to the transient stability of power systems. Therefore, the large-signal behavior of IBRs and its impact on transient stability must be studied.

This work studies this impact through the metric of critical clearing time (CCT). Impact of grid topology, generation mix and control modes of IBRs on CCT …


Bilevel Network Interdiction Models For Human Trafficking Disruption, Daniel Bruno Lopes Da Silva Aug 2025

Bilevel Network Interdiction Models For Human Trafficking Disruption, Daniel Bruno Lopes Da Silva

All Dissertations

In this dissertation, we study a series of bilevel network interdiction problems motivated by applications in human trafficking disruption. First, we consider a bilevel network interdiction problem where the follower aims to maximize the amount of flow from the source node to the sink node and the leader aims to minimize the number of arcs from a critical set that have positive flow on them in the solution obtained by the follower. This problem models the situation where an anti-trafficking agent wants to minimize the number of people affected by the trafficking operations whereas the trafficker wants to maximize trafficking …


Modeling Disaster Resilience Through A Human-Centered Lens: Exposure, Vulnerability And Adaptation, Tong Liu Aug 2025

Modeling Disaster Resilience Through A Human-Centered Lens: Exposure, Vulnerability And Adaptation, Tong Liu

All Dissertations

The core of reframing and operationalizing disaster resilience with a human-centered lens is to incorporate concepts from socio-ecological resilience into engineering resilience to better understand the humans’ capability for disaster adaptation. Existing studies have drawn practical implications by identifying actionable thresholds for infrastructure systems under disasters, which can be easily applied by policymakers, emergency managers and municipal agencies. However, how individuals interact with, respond to, or adapt under these infrastructure thresholds remain understudied. This hinders the operationalization of disaster resilience at the human scale.

First, I examined exposure by analyzing how configuration and distribution of urban infrastructure systems, such as …


Synthesis And Characterization Of Magnetic Nanoparticles To Study Effective Magnetic Anisotropy For Biomedical And Catalytic Applications, Alexander Malaj Aug 2025

Synthesis And Characterization Of Magnetic Nanoparticles To Study Effective Magnetic Anisotropy For Biomedical And Catalytic Applications, Alexander Malaj

All Dissertations

This dissertation focuses on understanding how to tune the magnetic properties of nanoparticles through controlling the effective magnetic anisotropy (Keff), which is a key variable in determining a nanoparticle’s Néel relaxation time, which will dictate its magnetic behavior in various applications. In this work, magnetocrystalline anisotropy is tuned by synthesizing tri-metallic substituted ferrite (Fe3-x-yMnxCoyO4) nanoparticles with specific metallic compositions that were informed by computer simulations using density functional theory (DFT) to target magnetocrystalline anisotropy values. A drip synthesis was used to control the size and composition of the tri-metallic ferrites, which were revealed to be monodisperse and compositionally mixed by …


Constructing A State: Canals And The Transformation Of The Economy, Politics, And Finance In Nineteenth-Century New York, Youwei Xing Aug 2025

Constructing A State: Canals And The Transformation Of The Economy, Politics, And Finance In Nineteenth-Century New York, Youwei Xing

All Dissertations

This dissertation consists of three essays in economic history, unified by a focus on one of America's earliest transportation infrastructures, the canal system, in nineteenth-century New York. Each chapter explores a different aspect of the state's transformation: its economy, politics, and finance, each of which helped construct New York as the Empire State.

The first chapter studies the economic impact of canals on economic modernization from three aspects: sectoral transition, urbanization, and banking development. Contrary to much of the modern literature finds transportation infrastructure leads to decentralization, I find the opposite-evidence of centralization. Specially: (1) canal towns experienced a transition …


Fleet Algorithm Design For Pooled Rideshare: Integrating Human Factors, Simulation, And Optimization, Joseph Paul Aug 2025

Fleet Algorithm Design For Pooled Rideshare: Integrating Human Factors, Simulation, And Optimization, Joseph Paul

All Dissertations

This dissertation explores the study the integration of human factors modeling and rideshare fleet control algorithms. Pooled rideshare is a unique transportation mode offering that allows riders increased flexibility and accessibility over public transportation, and decreased cost relative to personal vehicles or traditional rideshare. Additionally, relative to personal vehicles, pooled rideshare offers reduced costs and options for those with difficulty obtaining transportation. Prior research in the space typically focused on modeling human behavior, or optimizing system performance, but a lack of integration of the concepts leads to unrealistic or underutilized outcomes. To tackle this problem, novel rideshare assignment, and repositioning …


Supporting Programmers Answering The Hard-To-Answer Questions Through The Use Of Large Language Models, Haixin Zhou Aug 2025

Supporting Programmers Answering The Hard-To-Answer Questions Through The Use Of Large Language Models, Haixin Zhou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Programmers often face hard-to-answer questions when working on large-scale projects. Not only during team collaborations, but also during interruptions such as meetings, having to suddenly work on another project, or even just taking a break are major reasons these questions arise, as programmers have to regain the context, knowledge, and mental state to resume the work. Traditional text editors such as GitHub do provide a built-in history system, but they lack historical context behind the editing to answer such questions.

To address this issue, we developed an experimental extension, Code History, on Visual Studio Code (VS Code) in the hope …


Integration Of Highly Mismatched Iii-Sb Virtual Substrates On Silicon Via Interfacial Misfit Arrays For Short-, Mid-, And Long-Wave Infrared Applications, Trent Garrett Aug 2025

Integration Of Highly Mismatched Iii-Sb Virtual Substrates On Silicon Via Interfacial Misfit Arrays For Short-, Mid-, And Long-Wave Infrared Applications, Trent Garrett

Boise State University Theses and Dissertations

Lattice constants of the III-V semiconductors range from 5.45 Å (GaP) to 6.48 Å (InSb). III-V semiconductors are grown on commercially available substrates made from binary III-V materials (e.g., GaAs, InP, and GaSb), or group IV materials (e.g., Si or Ge). These substrates offer very high quality, but only offer access to a small number of specific lattice constants. Given this constraint, it is desirable to develop growth methods that would allow the grower to modulate from the substrate lattice constant into the lattice constant of the material structure under investigation.

Device structures made from III-V semiconductors lattice-mismatched to these …


Failure Study Of Silicon Gated Field Emitter Arrays: Experiment And Simulation, Rushmita Bhattacharjee Aug 2025

Failure Study Of Silicon Gated Field Emitter Arrays: Experiment And Simulation, Rushmita Bhattacharjee

Boise State University Theses and Dissertations

Silicon-based Gated Field Emitter Arrays (Si-GFEAs) are among the most well-developed field emitters. They are being actively explored for vacuum transistors and microwave vacuum electron devices due to their high-frequency performance, radiation resistance, and thermal stability up to 400 °C. However, their long-term reliability is limited by sudden failure events, resulting in cathodic vacuum arcs. This dissertation presents a combined experimental and simulation-based investigation into arc initiation mechanisms in Si-GFEAs. Different device arrays were tested under normal operation in vacuum at 10^-7 Torr with gate voltages of 50-70 V and emission currents from tens of nA to tens of µA. …


Engineering Properties And Stress-Strain Behavior Of Bcsa Concrete: Flexural Design Parameters, Strain Measurement Methods, And Models, Gabriel R. Johnson Aug 2025

Engineering Properties And Stress-Strain Behavior Of Bcsa Concrete: Flexural Design Parameters, Strain Measurement Methods, And Models, Gabriel R. Johnson

Graduate Theses and Dissertations

Belitic calcium sulfoaluminate (BCSA) cement concrete has gained popularity due to advantages over portland cement (PC), including, its fast-setting, high early strength gain, high durability, and reduced global warming potential. Though primarily used for pavement repair, it has good potential for structural applications. Building codes like ACI 318:19 permit alternative cement materials like BCSA cement if they can be shown to have adequate and predictable structural, durability, and fire performance comparable to PC concrete. This study evaluates the structural and mechanical behavior of BCSA cement concrete, measuring standard engineering properties and comparing results to PC concrete and code prediction equations. …


Mathematical Modeling Of Effects Of Tumor Location On Lung Function., Lamargaret Temukisa Johnson Aug 2025

Mathematical Modeling Of Effects Of Tumor Location On Lung Function., Lamargaret Temukisa Johnson

Master of Engineering Theses

Lung cancer has the highest rates of incidence and mortality of all cancers. Most lung cancer tumors are Non-Small Cell Lung Cancer (NSCLC). NSCLC patients with lesions in the upper lobes are found to have better prognosis compared to those with lesions in the middle and lower lobes. Previous studies have suggested various causes for this discrepancy at both the organ-scale and tissue-scale. To model NSCLC growth in different locations within the lung, an organ scale lung model and tissue scale tumor model were coupled through the tissue pressure, and oxygen and carbon dioxide partial pressures. The coupling was used …


Feasibility Study On Using Blue Clay As A Supplementary Cementitious Material (Scm)., Clark Lemon Aug 2025

Feasibility Study On Using Blue Clay As A Supplementary Cementitious Material (Scm)., Clark Lemon

Master of Engineering Theses

An effective strategy for reducing CO2 emissions in the global cement industry is replacing a percentage of cement with supplementary cementitious materials (SCMs). As the availability of conventional SCMs such as fly ash and slag is decreasing, alternative SCMs such as calcined clays have been studied for their use as effective pozzolans. The present work investigates the feasibility of using a waste product from the quarrying industry known as blue clay as a viable SCM. It is composed of multiple clay minerals, predominantly muscovite. Raw and calcined at four temperatures (500, 650, 800, and 950°C), blue clay was analyzed …


Growth And Characterization Of Thin Film Gase On Si(111) And Sio2/Si(001) Substrates By Molecular Beam Epitaxy, Christopher John Hocevar Aug 2025

Growth And Characterization Of Thin Film Gase On Si(111) And Sio2/Si(001) Substrates By Molecular Beam Epitaxy, Christopher John Hocevar

Graduate Theses and Dissertations

Gallium selenide (GaSe) is a thin-film semiconducting material with promising optoelectronic properties, including a tunable bandgap, high photosensitivity, and atomic-layer scalability. These characteristics make it suitable for devices such as photodiodes, FETs, MOSFETs, Hall effect sensors, and p–n diodes. In this study, GaSe thin films were grown on SiO2 and Si(111)-7×7 substrates using molecular beam epitaxy (MBE) to compare growth behavior across different substrates. The films were characterized using Raman spectroscopy, X-ray diffraction (XRD), atomic force microscopy (AFM), photoluminescence (PL) spectroscopy, and reflection high-energy electron diffraction (RHEED). RHEED confirmed the 7×7 reconstruction of the Si(111) surface and the amorphous nature …


Synthesis, Structural Characterization And Optical Studies Of Silver-Indium-(Zinc)-Chalcogenide Fluorescent Quantum Dots, Sujal Acharya Aug 2025

Synthesis, Structural Characterization And Optical Studies Of Silver-Indium-(Zinc)-Chalcogenide Fluorescent Quantum Dots, Sujal Acharya

Graduate Theses and Dissertations

Developing a non-toxic, high-performance fluorescent nanomaterial is crucial for overcoming the environmental and health restrictions of current cadmium, and lead based quantum dots (QDs), which limit the application of quantum dots in optoelectronics and bioimaging. In this thesis, we synthesized environmentally friendly AgInS2 QDs by a colloidal method, systematically altering the In/Ag precursor ratio from 2 to 6 to study the impact on their optical and photophysical properties. Our goals were to find the optimal stoichiometry for maximum quantum efficiency and stability. We also investigated further improving optical and photophysical properties through shelling with ZnS. The emission spectra appeared broad, …


Complex System Governance And Cyber Operations, Willie Gernard Mccallister Aug 2025

Complex System Governance And Cyber Operations, Willie Gernard Mccallister

Engineering Management & Systems Engineering Theses & Dissertations

This dissertation examines the potential integration of Complex System Governance (CSG) within cybersecurity, emphasizing the development of a reference model for Cybersecurity Infrastructures. Traditional strategies for securing digital environments have struggled to address the intricate and dynamic layers inherent in modern cybersecurity systems. The purpose of this research is to explore the applicability of CSG as a framework to assess cybersecurity infrastructure using a case study research design. The research addresses two key questions: (1) How can the CSG reference model be adapted to explore cybersecurity infrastructure? (2) What results from CSG based exploration of cybersecurity infrastructure through a case …


Two Analytic Issues Arising From Models In Probability And Materials Science, Giang Vu Thanh Nguyen Aug 2025

Two Analytic Issues Arising From Models In Probability And Materials Science, Giang Vu Thanh Nguyen

Mathematics & Statistics Theses & Dissertations

This dissertation explores two distinct topics centered on mathematical models in probability theory and materials science. The first part investigates a series of functions derived from an adaptive algorithm designed to address the score-based secretary problem, a classic challenge in probability theory. This problem involves making immediate decisions to select the best candidate from a sequence of interviews. The algorithm aims to maximize the probability of selecting the optimal candidate based on observed scores. We prove two fundamental analytic properties of this sequence of functions as a theoretic support of the algorithm: first, the functions in the sequence each possess …


A Strict Physicality-Preserving Scheme For A 2d Q-Tensor Flow With A Singular Potential, Md Mashud Parvez Aug 2025

A Strict Physicality-Preserving Scheme For A 2d Q-Tensor Flow With A Singular Potential, Md Mashud Parvez

Mathematics & Statistics Theses & Dissertations

Nematic liquid crystals are a state of matter that exhibit properties between those of conventional liquids and solid crystals. Their unique ability to align molecules in specific directions makes them essential in various applications, including display technologies and advanced materials. To model their complex behavior, mathematical frameworks such as the Q-tensor model are used to describe the orientation and degree of molecular order. In this work, we introduce a numerical scheme for a two-dimensional (2D) dynamic Q-tensor model, which is formulated as an L2-gradient flow driven by the liquid crystal free energy and incorporates a singular potential to …


Towards Improving Computational Modeling Of The Lumbar Spine - Impact Of Material Properties And Laminotomy On Spinal Biomechanics, Isaac K. Kumi Aug 2025

Towards Improving Computational Modeling Of The Lumbar Spine - Impact Of Material Properties And Laminotomy On Spinal Biomechanics, Isaac K. Kumi

Mechanical & Aerospace Engineering Theses & Dissertations

Spinal ligaments play a crucial role in maintaining the mechanical stability of the lumbar spine. These dense, collagenous tissues not only resist excessive motion but also distribute loads between spinal components to protect neural structures. Traditionally, the mechanical response of ligaments has been modeled using linear elastic assumptions, which treat the tissue as having a constant stiffness regardless of loading history. While this simplifies analysis, it fails to capture the time-dependent behaviors, such as creep, stress relaxation, and hysteresis, that are characteristic of biological tissues.

Viscoelastic modeling may provide a more physiologically accurate representation by incorporating both elastic and viscous …


A Methodology For Model-Based Certification, Jay Albert Silverman Aug 2025

A Methodology For Model-Based Certification, Jay Albert Silverman

Engineering Management & Systems Engineering Theses & Dissertations

A need for a single source of knowledge for design decisions has led to the development of a new field of systems engineering, model-based systems engineering (MBSE) (Delligati, 2014). System certification is defined as affirming that regulatory requirements for a system have been met (Goodwin & Juzaitis, 2006). System certification is a specific application of system validation. System verification can be defined as ensuring that the system of interest (SOI), as designed, is in accordance with the design inputs/requirements. System validation can be defined as ensuring that the SOI, as designed, meets the defined system needs (Wolfgand, Katz, & Wheatcraft, …


Computational Modeling For Automatic Superconducting Cavity Fault Prediction And Classification Using Time Series Signals, Md Monibor Rahman Aug 2025

Computational Modeling For Automatic Superconducting Cavity Fault Prediction And Classification Using Time Series Signals, Md Monibor Rahman

Electrical & Computer Engineering Theses & Dissertations

Processing multivariate time series signals collected from sensor networks is challenging because of complex temporal dependencies and non-stationarity. With the advent of artificial intelligence (AI) like machine learning and deep learning, it has become possible to process sensor-driven time series data more effectively than traditional statistical methods.

This dissertation aims to develop machine learning and deep learning models to address machine fault diagnosis using multivariate time series signals collected from the Continuous Electron Beam Accelerator Facility (CEBAF) at Jefferson Lab. The first goal of the proposed work is to develop deep learning–based classification models and an unsupervised fault clustering approach …


Multimedia Forensics: Identification And Verification Of Source Camera, Vehicle Speed Estimation, And Deepfakes Detection, Jiajun Jiang Aug 2025

Multimedia Forensics: Identification And Verification Of Source Camera, Vehicle Speed Estimation, And Deepfakes Detection, Jiajun Jiang

Electrical & Computer Engineering Theses & Dissertations

This dissertation advances multimedia forensics by addressing three critical research areas that enhance the authenticity verification and analysis of digital media. Multimedia forensics, which encompasses techniques for examining images, videos, audio, and text, faces increasing challenges due to sophisticated editing tools and massive data volumes. In the first study, a fast source camera identification and verification method based on PRNU analysis is proposed for video forensic investigations. By integrating camera rolling and I-frame analysis, this approach achieves a processing speed improvement of at least 15 times over conventional frame-by-frame methods while reducing false positives. The second study focuses on vehicular …


Analysis On Plasma Propulsion Thruster Material Reconfiguration For Thrust Stabilization, Chinedumu Chidiebere Okafo Aug 2025

Analysis On Plasma Propulsion Thruster Material Reconfiguration For Thrust Stabilization, Chinedumu Chidiebere Okafo

Mechanical & Aerospace Engineering Theses & Dissertations

Rocket propulsion has been a primary focus for scientific and technical advancement supporting space exploration. For long-duration, low-thrust space missions, propulsion systems designed with plasma energy as the primary source for generating thrust are of high interest. Plasma energy, like electric propulsion, involves the excited state of ionized atoms, where the ionized particles are separated and then act as a propellant to push a spacecraft in the intended direction for flight. Although more energy efficient compared to traditional rocket systems, plasma propulsion has the deficiency of consistent erosion of the metallic containment substrate, as plasma is being generated and released …


Inter-Cellular Forces Modulate Cell-Ecm Traction Forces, Zaria Booth Aug 2025

Inter-Cellular Forces Modulate Cell-Ecm Traction Forces, Zaria Booth

Mechanical & Aerospace Engineering Theses & Dissertations

Epithelial cells are among the most abundant cell types in the human body, making up sheets of epithelial tissues that cover the linings of organs and body cavities. Cellular adhesion and force transmission across epithelial tissues are crucial in maintaining tissue integrity and ensuring proper tissue regeneration. Defects in cellular force transmission have been found in various diseases, including cancer. Force transmission at cell-cell and cell-ECM junctions drive cell survival and development. It has been previously shown that changes in cell-ECM traction directly modulates forces at cell-cell contacts. In this study, we aim to determine the effects of perturbations in …


Input Structure Based Optimization For Privacy Preserving Ai Systems, Feng Yizhou Aug 2025

Input Structure Based Optimization For Privacy Preserving Ai Systems, Feng Yizhou

Electrical & Computer Engineering Theses & Dissertations

As Artificial Intelligence (AI) systems become increasingly integrated into critical domains, ensuring privacy-preserving model design and system deployment has become a pressing priority. Safeguarding both sensitive user data and proprietary model parameters is critical throughout the AI model and system, from data acquisition and pre-processing to model inference and deployment. However, existing privacy-preserving frameworks face several limitations, including fragmented data ownership, incomplete protection across system stages, substantial computational overhead, and poor scalability to modern architectures such as large language models. This dissertation explores a unifying optimization strategy centered on input structure design to address these challenges. The core idea is …


Design And Validation Of A High-Frequency Multi-Output Dc-Dc Converter For Radar Power Applications, Tory Sutton Aug 2025

Design And Validation Of A High-Frequency Multi-Output Dc-Dc Converter For Radar Power Applications, Tory Sutton

Graduate Theses and Dissertations

Modern radar systems and advanced electronics demand compact, efficient, and reliable power solutions capable of delivering multiple tightly regulated voltage rails under strict size, weight, power, and reliability (SWaP-R) constraints. This thesis presents the design, implementation, and validation of a high-frequency (460 kHz – 1 MHz), multi-output DC-DC converter for a mission?critical radar platform, addressing both integration and performance requirements. The first implementation, an isolated modular converter (IMC), utilizes isolated silicon?based DC-DC modules to deliver twelve isolated voltage outputs from a single input. This approach provided robust electrical isolation, simplified system integration, and minimized design risk, making it well-suited for …


Controlling Electroless Deposition On Polymer Interfaces Towards Discrete Functional Particle Synthesis, Grecia Pierina Alvarado Munoz Aug 2025

Controlling Electroless Deposition On Polymer Interfaces Towards Discrete Functional Particle Synthesis, Grecia Pierina Alvarado Munoz

Graduate Theses and Dissertations

Electroless deposition is a process that facilitates the formation of metal layers on surfaces through the reduction of metal ions onto a surface in the presence of a sacrificial reducing agent. This process can be applied to synthesize conductive metal layers on insulators such as glass or polymers. The kinetics of heterogeneous deposition depend on the interfacial surface chemistry, including the presence of added catalyst materials, as well as the bulk chemical environment, such as the concentration of metal ions and sacrificial reductants. Furthermore, the homogeneous formation of metal nanoparticles may compete with the deposition reaction, adversely affecting the control …


Enhancing The Design Of Strained Superlattice Gallium Arsenide Based Photocathodes With Distributed Bragg Reflector, Adam D. A. Masters Aug 2025

Enhancing The Design Of Strained Superlattice Gallium Arsenide Based Photocathodes With Distributed Bragg Reflector, Adam D. A. Masters

Electrical & Computer Engineering Theses & Dissertations

Particle accelerators play a crucial role in our understanding of matter and the universe and have numerous practical applications in various fields. These devices enable scientists to examine the smallest components of matter, study the forces that govern their interactions, and probe conditions from the early universe. Moreover, accelerators are valuable in medicine, industry, and research, enhancing imaging methods, cancer therapies, and manufacturing techniques. As the experiments conducted at these facilities evolve and require higher precision, improved particle sources must continue to advance to keep up with their requirements. To do that, we enhanced the design of spin polarized electron …


Effect Of Moderate Decrease In Contractility On Epithelial Cell-Cell Contacts Under External Stretch, Saika Sharmin Aug 2025

Effect Of Moderate Decrease In Contractility On Epithelial Cell-Cell Contacts Under External Stretch, Saika Sharmin

Mechanical & Aerospace Engineering Theses & Dissertations

Epithelial tissues are characterized by extensive cell–cell contacts and often subject to stretch during normal function. Cell-cell contact adhesion strength maintains mechanical continuity from cell to cell. Mechanical forces exerted by cells via actomyosin contractility are known to strengthen cell-cell adhesions to a certain extent. While it is known that a large decrease in contractility causes cell-cell contact rupture due to weakened adhesions, it is unclear how a moderate reduction in contractility affects cell-cell junction stability. Here, we studied how a moderate inhibition of non-muscle myosin II (NMII) affects the integrity of epithelial cell-cell contacts, especially when subject to the …


Advanced Analytical Biosensing For Cancer Detection And Neural Diagnostics Using Tapered Optical Fiber (Tof), Protonic, And High Throughput Microplate –Based Technologie, Bayan Hassan Alharbi Aug 2025

Advanced Analytical Biosensing For Cancer Detection And Neural Diagnostics Using Tapered Optical Fiber (Tof), Protonic, And High Throughput Microplate –Based Technologie, Bayan Hassan Alharbi

Chemistry & Biochemistry Theses & Dissertations

This dissertation investigates the development and application of advanced biosensing technologies to enhance early disease detection, neurological diagnostics, and bioactive compound evaluation. The research spans four key areas. First, it introduces tapered optical fiber (TOF)-based plasmonic biosensors for the non-invasive detection of prostate cancer, demonstrating high sensitivity and specificity compared to conventional diagnostic methods.

Second, it explores the use of fluorescent biosensors to test the Transmembrane Electrostatically Localized Proton (TELP) theory, shedding light on the role of localized protons in neuronal signaling and energy transfer. Third, the work presents a high-throughput, microplate-based biosensing platform for analyzing mitochondrial function under nanosecond …