Digital Commons Network^™

Ruptured Atlas: A Trauma-Informed Approach To Spatial Storytelling For Survivors Of Genocide (The Case For Yazidis In Iraq), Sana Murrani, Kimbal Bumstead, Zoe Paris, Ghazi Murad Ismael, Jameela Rasho, Omeed Khider Joqey

School of Art, Design and Architecture

The Ruptured Atlas project (December 2023 – December 2024) employs innovative, participatory mapping techniques to document the complex spatial and lived experiences of the Yazidi community in the aftermath of the genocide perpetrated by ISIS, which commenced in August 2014. This collaborative effort involves 15 Yazidi researchers and key partners, culminating in an online atlas and a trauma-informed policy toolkit. Designed to influence housing and migration policies in both Iraq and the UK, the project prioritises trauma-informed practices and community empowerment. The online atlas was not only a conceptual device, but a vital visual tool, enabling participants to represent trauma …

Predicting The Impact Of Climate Change On The Distribution Of Monodelphis Domestica (Wagner, 1842), Salise Sepulveda, Noé U. De La Sancha

DePaul Discoveries

Understanding the impact of climate change on species distribution is necessary to properly develop plans that conserve or prepare for maintenance of crucial ecosystems. Monodelphis domestica is a small mammal species native to Argentia, Bolivia, Brazil, and Paraguay. This species is known for its high adaptability and preference for living in wet conditions. Using bioclimatic variables, generalized linear models (GLM), and Coupled Model Intercomparison Project Phase 6 (CMIP6) we predicted how this species distribution will change within the next 75 years under different climate and anthropogenic changes. The results have shown that the distribution of M. domestica will remain relatively …

Using Synchrotron Wide-Angle X-Ray Scattering To Study Collagen Degradation In Second Metacarpal Bones, Zeel Sheth, Misha Romanov, Ruby Schwieger

DePaul Discoveries

The study examines female human second metacarpal (mc2) bones from early medieval cemetery at Greding, Germany, using high-energy Wide-Angle X-ray Scattering (WAXS) at beamline 1-ID of the Advanced Photon Source (APS) at Argonne National Laboratory. Rietveld refinement showed that carbonated apatite lattice parameters did not correlate with estimated age-at-death. For six of the mc2, widths of 00.2 and 00.4 diffraction peaks were substantially narrower than those of a modern (non-diagenetically altered) mc2 and of the other four ancient mc2. The peak width results are interpreted as indicating that four of the ten ancient mc2 retain substantial collagen and six of …

Race/Ethnicity, Living Arrangements, And Access To Healthcare Among Older Adults With Alzheimer’S Disease In The United States: Multiple Systematic Reviews In Relation To Health Outcomes, Chela Reiss, Grace Vethacke

DePaul Discoveries

Alzheimer’s disease (AD) is a neurodegenerative condition primarily affecting older adults. It is a growing public health crisis that affects memory, thinking, and behavior. The number of adults aged 65 and older is projected to reach 98.2 million by 2060, leading to a continued rise in the prevalence of AD. Understanding the socioeconomic factors that influence health outcomes in patients with Alzheimer's Disease and Related Dementias (ADRD) is essential in addressing the disparities within patient care and quality of life. This systematic review examined three socioeconomic factors - race/ethnicity, living arrangements, and access to healthcare - and their related health …

Life Of Moo Deng, The Internet Sensation Pygmy Hippopotamus: An Overview Of The Biology And Conservation Breeding Program In Thailand, Ampika Thongphakdee, Atthapon Nundee, Umaporn Maikeaw, Narongwit Chodchoy, Chainarong Punkong, Kaywalee Chatdarong

The Thai Journal of Veterinary Medicine

The hippopotamus, commonly known as the hippo, is classified into two extant species: the common hippopotamus (Hippopotamus amphibius) and the pygmy hippopotamus (Choeropsis liberiensis). Pygmy hippos are fascinating creatures native to the forests and swamps of West Africa. Their survival is increasingly threatened by habitat loss resulting from agricultural expansion and urban development. As the population declines, zoological institutions play a crucial role in conservation by acting as genetic reservoirs and promoting public awareness of wildlife and environmental protection. “Moo Deng”, a pygmy hippo, whose name in Thai has gained international recognition, represents a notable success …

Exploring Bio-Inspired Agent Behaviors From Ants For Robotic Swarm Fault Resilience, James Hand

Discovery Day - Daytona Beach

As Multi-Agent Systems (MASs) become increasingly involved in every aspect of everyday life, the need to maintain reliability and resilience within these systems grows. However, there is a need for control schemes and agent behaviors that provide security against these threats while also avoiding large degradation in system performance as a tradeoff. Current research has covered a wide breadth of avenues and strategies that provide measurable resilience to faulted agents. However, these strategies often require group consensus, specialized observer agents, or identification of faulted agents, which can weaken overall system performance. This work presents an alternative solution through individual agent …

Stars: System Lifecycle Perspective Of An Autonomous Robotic Swarm Test Arena, Rasika Ravindra Kale, James Hand, Jonah Kohlmeyer, Dawson Jones, Nathan Geroge

Discovery Day - Daytona Beach

Swarm robotics presents a robust platform for investigating distributed control, adaptive behavior, and autonomous coordination within a system of systems framework. The Roving Swarm comprises 24 low-computation robots, emulating eusocial insect behavior through vision-sensing and decentralized decision-making. A key subsystem, the motion-sensing and interaction module, integrates real-time object detection, swarm coordination, and environmental responsiveness, employing Pixy2 vision sensors and Arduino 33 IoT controllers. The robots use DC motors for actuation, enabling structured rotational and translational motion, and demonstrate dynamic adaptability to environmental cues such as light intensity and peer movements. Designed for modularity and scalability, the system lifecycle of the …

The Impact Of Cybersecurity Research In Problem-Solving Through A Swarm Infiltration Exercise, Noa Teed

Discovery Day - Daytona Beach

The study explores the impact of a six-week cybersecurity course on undergraduate students' problem-solving approaches to complex challenges, employing interactive robotic swarm simulations as a practical testbed. While the exact algorithm implementation is beyond the scope of this experiment, it serves as a proof of concept. In this experiment, inspired by ants' chemical communication (CHC) profiles for colony member identification, the simulations utilize LED lights and a "handshake" algorithm, allowing robots to recognize "friendly" agents. This innovative approach aims to assess how formal education in cybersecurity bolsters students' analytical thinking and strategic development capabilities.

Conducted in two phases, the research …

Enhancing The Quality Of Biologically Inspired Solutions In A Classroom Design Task, Mikayla Dutkiewicz

Discovery Day - Daytona Beach

This study seeks to explore whether exposure to biologically inspired design can enhance the quality of undergraduate student engineering design solutions, with a specific focus on requirement fulfillment. Motivated by a gap in the literature regarding the direct impact of biologically inspired design on student outcomes, this research aims to address the lack of empirical evidence on the effectiveness of biologically inspired design as a pedagogical tool. While existing literature extensively explores the "how" of biologically inspired design implementation, such as frameworks and methodologies, there is limited understanding of its tangible effects on design quality for novice designers (students). This …

Dynamics Of Random Graphs And Interacting Particle Systems, Aritra Mandal

Doctoral Theses

The talk will be based on the thesis which has broadly two objectives. In the first part of the thesis we study a certain random dynamics of discrete sparse graphs on n vertices(based on the Moran model) and understand the limit as n goes to infinity. In the second part of the thesis we provide a trajectorial representation for a semi linear parabolic partial differential equation. In this talk we will mainly focus on the results concerning the dynamics of sparse graphs. We will begin with the preliminaries of the sparse graphs and convergences. Following which we will define the …

Systems Genetics Reveals The Influence Of Expression Qtls In Mouse Embryonic Stem Cells On Transcriptional Variation Later In Differentiated Neural Progenitor Cells., Selcan Aydin, Daniel A Skelly, Hannah B Dewey, J Matthew Mahoney, Ted Choi, Laura G Reinholdt, Christopher L. Baker, Steven C. Munger

Faculty Research 2025

Genetic variation leads to phenotypic variability in pluripotent stem cells that presents challenges for regenerative medicine. Although recent studies have investigated the impact of genetic variation on pluripotency maintenance and differentiation capacity, less is known about how genetic variants affecting the pluripotent state influence gene regulation later in development. Here, we characterized expression of 12,000 genes in a large panel of donor-matched Diversity Outbred mouse embryonic stem cell and mouse neural progenitor cell lines. QTL mapping identified 4,060 expression QTLs in mouse neural progenitor cells, including 2,998 local and 1,062 distant expression QTLs. In a comparison of mouse neural progenitor …

Understanding Youth Violence Through A Socio-Ecological Lens, Yok-Fong Paat, Kristopher Hawk Yeager, Erik M. Cruz, Rebecca Cole, Luis R. Torres-Hostos

School of Social Work Faculty Publications

Youth violence—the deliberate use of physical force or harm by young people between the ages of 10 and 24 to intimidate or cause harm to others, both online and offline—is a critical public health issue in the United States. Yet, successfully predicting future violent offenders is a complex and challenging task, as the question of why some youths resort to extreme violence while others refrain from it—despite facing similar risk factors—remains widely debated. This article highlights both risk and protective factors of youth violence through a socio-ecological lens to offer a comprehensive understanding of the multifaceted factors driving youth violence …

Enhancing Employment Readiness Of Information Technology (It) Professionals Of India - A Talent Refactoring Approach, Lakshminarayanan K.V

Theses and Dissertations

The Indian Information Technology (IT) sector is undergoing significant transformation due to the adoption of Industry 4.0 technologies such as Artificial Intelligence, Internet of Things, cloud computing, and cyber-physical systems. These changes have redefined workforce expectations, shifting employment readiness from mere technical competence to a holistic combination of adaptability, behavioral attributes, and continuous learning capabilities. In this context, the study proposes a Talent Refactoring Framework to address employability in a rapidly evolving VUCA–BANI environment by integrating organizational, career-oriented, and individual dimensions.

A review of existing literature reveals notable gaps in understanding employment readiness as an ecosystemic and psycho-social construct, particularly …

Mitigation Of Micro-Nano Plastics Facilitated Using Microbial And Nanophotonic Degradation, And Smart Material Designs, Ashok Vaseashta, Surik Khudaverdyan, Gor Gevorgyan, Ioan Stamatin, Shushanik Kazaryan, Ashkhen Hovhannisyan, Susanna Tiratsuyan, Ludmila Sidorenko, Tatiana Gutul, Inna Rastimesina, Anatolie Sidorenko

Micro-Nano Plastics in Water: Characterization, Cure and Prevention

Please click Additional Files below to see the full abstract

A Single High-Zinc Activation Enhancer Can Control Two Genes Oriented Head-To-Head In Caenorhabditis Elegans, Hanwenheng Liu, Brian Earley, Adelita Mendoza, Patrick Hunt, Sean Teng, Daniel Luke Schneider, Kerry Kornfeld

2020-Current year OA Pubs

Enhancers play critical roles in gene expression, but a full understanding of their complex functions has yet to be defined. The cellular response to excess zinc levels in Caenorhabditis elegans requires the HIZR-1 transcription factor, which binds the high-zinc activation (HZA) enhancer in the promoters of multiple target genes. Cadmium hijacks the excess zinc response by binding and activating HIZR-1. By analyzing the genome-wide transcriptional response to excess zinc and cadmium, we identified two positions in the genome where head-to-head oriented genes are both induced by metals. In both examples, a single predicted HZA enhancer is positioned between the two …

Artificial Turf Versus Natural Grass: A Case Study Of Environmental Effects, Health Risks, Safety, And Cost, Iman S. Cumberbatch, Leonard Richardson, Emma Grant-Bier, Mustafa Kayali, Mutanu Mbithi, Roberto F. Riviere, Eline Xia, Hailey Spinks, Gabrielle Mills, Amy R. Tuininga

PSEG Institute for Sustainability Studies Publications

While natural grass has been a reliable recreational surface for decades, artificial turf has gained popularity due to its durability, supposed ability to save water, and lower associated costs for municipalities and schools. Growing environmental and health concerns associated with artificial turf have prompted a necessary comparison of the environmental impact, chemical exposure, injury rates, surface heat, and costs of turf with natural grass. The township of Verona, New Jersey, engaged the PSEG Institute for Sustainability Studies’ Green Teams Program interns to perform an environmental impact assessment, literature review, and cost–benefit analysis to determine if the township should restore an …

First-In-Human Phase I Open-Label Study Of The Anti-Tim-3 Monoclonal Antibody Incagn02390 In Patients With Select Advanced Or Metastatic Solid Tumors, Martin E. Gutierrez, Shou Ching Tang, John D. Powderly, Ani S. Balmanoukian, Paul E. Hoyle, Zhiwan Dong, Lulu Cheng, Xiaohua Gong, John E. Janik, Nawel Bourayou, Omid Hamid

School of Medicine Faculty Publications

Background T-cell immunoglobulin and mucin domain-containing protein-3 (TIM-3) is an immune checkpoint receptor upregulated during anti-programmed death protein-1 (PD-1)/programmed death ligand-1 (PD-L1) immunotherapy for cancer. TIM-3 blockade may improve the antitumor activity of PD-1/PD-L1inhibition. This phase 1 study evaluated INCAGN02390, a novel, fully human Fc-engineered antibody against TIM-3. Methods INCAGN02390 was evaluated by dose escalation at 10-1600 mg infused in 14-day cycles (every 2 weeks [Q2W]) in pretreated patients with select advanced/metastatic immunogenic solid tumors. Objectives included evaluation of safety/tolerability and maximum tolerated dose (MTD) (primary), pharmacokinetics, preliminary antitumor activity, pharmacodynamics, and immunogenicity (secondary). Results Forty patients were enrolled and …

Plastic Waste Removal Options To Minimize Local Introduction Of Micro- Plastics In Antarctica, Clara Alvarez Hernandez, Nan Wu, Clara Manno

Micro-Nano Plastics in Water: Characterization, Cure and Prevention

Please click Additional Files below to see the full abstract

Computational And Imaging Approaches For Precision Characterization Of Bone, Cartilage, And Synovial Biomolecules., Rahul Kumar, Kyle Sporn, Vibhav Prabhakar, Ahab Alnemri, Akshay Khanna, Phani Paladugu, Chirag Gowda, Louis Clarkson, Nasif Zaman, Alireza Tavakkoli

Department of Medicine Faculty Papers

Abstract

Background/Objectives: Degenerative joint diseases (DJDs) involve intricate molecular disruptions within bone, cartilage, and synovial tissues, often preceding overt radiographic changes. These tissues exhibit complex biomolecular architectures and their degeneration leads to microstructural disorganization and inflammation that are challenging to detect with conventional imaging techniques. This review aims to synthesize recent advances in imaging, computational modeling, and sequencing technologies that enable high-resolution, non-invasive characterization of joint tissue health. Methods: We examined advanced modalities including high-resolution MRI (e.g., T1ρ, sodium MRI), quantitative and dual-energy CT (qCT, DECT), and ultrasound elastography, integrating them with radiomics, deep learning, and multi-scale modeling approaches. We …

Hemp Cultivation Under Off-Season High Tunnel Growth Chamber Environments In South Louisiana, Gabriel Lococo

LSU Master's Theses

Industrial hemp (Cannabis sativa) production in Louisiana began in 2020 with 932 acres cultivated for fiber and cannabidiol (CBD) extraction. By 2024, production had declined to just 58.4 acres (Louisiana Department of Agriculture and Forestry, personal communication). During the 2020–2021 season, over 40% of field-grown hemp was lost due to tropical storms, insect pressure, and diseases associated with warm, wet conditions. To mitigate these challenges, hemp was planted and harvested between November and January, a cooler period with reduced environmental stress.

‘Sour Citron’, a day-neutral cultivar, was selected for its insensitivity to photoperiod, enabling flowering during shorter days. …

Faculty Perceptions Of The Affective Domain In Entry-To-Practice Respiratory Therapy Education: An Exploratory Descriptive Qualitative Study, Jackie W. Davis

Graduate Theses, Dissertations, and Capstones

Background: The affective domain of learning is one of the three learning domains that comprise Bloom's Taxonomy of learning. The respiratory therapy profession places a great emphasis on the development and assessment of all three learning domains in entry-to-practice respiratory therapy education. While the cognitive and psychomotor domains receive significant attention, the affective domain of learning is often given less attention due to its complexity and lack of definition in the profession. Purpose: An exploratory descriptive qualitative study focused on exploring the affective domain of learning in entry-to-practice respiratory therapy education, specifically how the domain is defined, and …

Human Contributions To Global Soundscapes Are Less Predictable Than The Acoustic Rhythms Of Wildlife, Panu Somervuo, Tomas Roslin, Brian L. Fisher, Bess Hardwick, Deirdre Kerdraon, Dimby Raharinjanahary, Eric Tsiriniaina Rajoelison, Patrik Lauha, Lukas Griem, Petteri Lehikoinen, Pekka Niittynen, Esko Piirainen, Markus Lumme, Ville-Matti Riihikoski, Orlando Acevedo-Charry, Solny A. Adalsteinsson, Maaz Ahmad, Sandra Alcobia, Jón Aldará, Tad Dallas

Faculty Publications

Across the world, human (anthropophonic) sounds add to sounds of biological (biophonic) and geophysical (geophonic) origin, with human contributions including both speech and technophony (sounds of technological devices). To characterize society’s contribution to the global soundscapes, we used passive acoustic recorders at 139 sites across 6 continents, sampling both urban green spaces and nearby pristine sites continuously for 3 years in a paired design. Recordings were characterized by bird species richness and by 14 complementary acoustic indices. By relating each index to seasonal, diurnal, climatic and anthropogenic factors, we show here that latitude, time of day and day of year …

Parents Of Adolescents On Electronic Use And Attention Deficit Hyperactivity Disorder: Parental Perspectives, Sleep, Internalization, Jessica Wiepking

Walden Dissertations and Doctoral Studies

ADHD in adolescents is a common diagnosis, with exposure to daily electronic use. There is strong evidence for a relationship between electronic use and ADHD in adolescents. However, there is a gap on electronic use, internalized feelings, and sleep behaviors in ADHD adolescents and how sleep behaviors might impact that relationship. ADHD has its core symptoms that impact the individual daily. These symptoms need to be taken into consideration when looking at internalized feelings and sleep behavior patterns. The theoretical framework that aligns with this study is the Dopaminergic Dysregulation Theory (DDT). This theory is a module that suggests that …

Concentration And Composition Of Organic Contaminants In Blackfin Tuna, Yellowfin Tuna, And The Common Clubhook Squid In The Western Gulf Of Mexico, Lisa Rose-Mann

USF Tampa Graduate Theses and Dissertations

Cephalopods are an important component of pelagic food webs. They play ecological roles not only as predators but also as prey. However, their role as prey in the trophic transfer of organic contaminants to apex predators such as tunas in the Gulf of Mexico (GoM) is not well known. To investigate the importance of cephalopods in tuna diets, stomach samples were collected in February 2020 from tunas caught by rod and reel aboard the F/V Gulf Eagle near two large offshore floating oil/gas platforms in the northwestern GoM. Cephalopod samples were obtained from gut content analysis of 41 tunas caught …

From Novice To Expert: Preparing Your Peer Review, Diana M Proctor, Rachy Abraham, Shannon Esher Righi

Faculty, Staff and Student Publications

Peer review is the process by which the quality of scholarly work is assessed prior to being published, presented, or funded. The consequences of flawed research entering the public domain in the "post-truth" era highlight the need to improve peer review quality, which we believe can be achieved by standardizing training. Here, we aim to enhance the quality of published literature by presenting a systematic guide to train new reviewers (and aid experienced ones) in the art of peer reviewing the rigor of scientific manuscripts.

Genome Report: Whole-Genome Assembly Of The Relapsing Fever Tick Ornithodoros Turicata Dugès (Acari: Argasidae), Mackenzie Tietjen, Amanda R Stahlke, David Luecke, Perot Saelao, Sheina B Sim, Scott M Geib, Brian E Scheffler, Anna K Childers, Alexander R Kneubehl, Pete D Teel, Job E Lopez

Faculty, Staff and Students Publications

The soft tick family Argasidae contains vectors of medical and veterinary importance, but few molecular resources are available compared to hard ticks (Ixodidae). One example is Ornithodoros turicata, a recognized vector of Borrelia turicatae, causal agent of human relapsing fever, and a putative vector of African swine fever virus. To address the current lack of molecular resources for the Argasidae, we generated a chromosome-level genome assembly for O. turicata using PacBio sequencing in conjunction with an Illumina Hi-C library. The resulting reference genome has a total of 1.1 Gb in length and was assembled into 10 chromosomes and 368 unplaced …

Migration Delays At Head-Of-Tide Weirs Are A Function Of Tidal Cycles And River Flows In Anadromous Twaite Shad Alosa Fallax, Mark I.A. Yeldham, J. Robert Britton, Charles Crundwell, Peter Davies, Jamie R. Dodd, Chris Grzesiok, Andrew D. Nunn, Randolph Velterop, Jonathan D. Bolland

School of Biological and Marine Sciences

Riverine barriers can have significant negative impacts on the spawning migrations of anadromous fishes, with barriers of low passage efficiency limiting access to upstream spawning areas. Even fish that pass a barrier can be negatively affected via migration delays and energetic costs. The spawning migrations of 74 twaite shad Alosa fallax were tracked at two head-of-tide weirs on a bifurcated channel in the River Severn’s upper estuary, western England, to test how barriers in tidal areas can affect river entry and incur migration delays. Although the weirs had a combined passage efficiency of 98.9%, median passage time was 19.8 h, …

Inferring Chromosome Segregation Error Stage And Crossover In Trisomic Disorders With Application To Down Syndrome, Zhenhua Li, Wenjian Yang, Gang Wu, Ti-Cheng Chang, Zhongshan Cheng, Meenakshi Devidas, Mary Shago, Andrew J Carroll, Nyla A Heerema, Julie M Gastier-Foster, Brent L Wood, Lauren Sanclemente, Elizabeth A Raetz, Stephen P Hunger, Mignon L Loh, Eleanor Feingold, Tracie C Rosser, Emily G Allen, Stephanie L Sherman, Karen R Rabin, Philip J Lupo, Jun J Yang

Faculty, Staff and Students Publications

Errors in chromosome segregation during gametogenesis, such as nondisjunction (NDJ) errors, have severe consequences in human reproduction, and a better understanding of their etiology is of fundamental interest in genetics. Mapping NDJ errors to meiotic/mitotic stages typically requires proband-parent comparison, limiting its applicability. Herein, we develop Mis-segregation Error Identification through Hidden Markov Models (MeiHMM), a method for inferring NDJ error stage and crossover events based on only genomic data of trisomic probands. Guided by triallelic genotype/haplotype configurations, MeiHMM discerns the allelic origin at each locus, which informs NDJ error during gamete formation, without identifying the parental origin of the trisomy. …

Distinct Systemic Impacts Of Aβ42 And Tau Revealed By Whole-Organism Snrna-Seq, Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Xi Chen, Baiping Wang, Ao-Lin Hsu, Elizabeth Ochoa, Kevin F Bieniek, Shinya Yamamoto, Yi Zhu, Hui Zheng, Yanyan Qi, Hugo J Bellen, Hongjie Li

Faculty, Staff and Students Publications

Both neuronal and peripheral tissues become disrupted in Alzheimer's disease (AD). However, a comprehensive understanding of how AD impacts different tissues across the whole organism is lacking. Using Drosophila, we generated an AD Fly Cell Atlas (AD-FCA) based on whole-organism single-nucleus transcriptomes of 219 cell types from flies expressing AD-associated proteins, either human amyloid-β 42 peptide (Aβ42) or Tau, in neurons. We found that Aβ42 primarily affects the nervous system, including sensory neurons, while Tau induces accelerated aging in peripheral tissues. We identified a neuronal cluster enriched in Aβ42 flies, which has high lactate dehydrogenase (LDH) expression. This LDH-high cluster …

Callison College Promotional Book: Japan, Callison College

Callison College and School of International Studies

No abstract provided.