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2025

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Callison And Raymond College Course Offerings, Callison College Jul 2025

Callison And Raymond College Course Offerings, Callison College

Callison College and School of International Studies

No abstract provided.


Tips For Inclusive Postsecondary Education Programs On College Campuses: Peer Mentors’ Perspectives On Access And Inclusion, Laura N. Sarchet, Kristen Love, Martha Mock Jul 2025

Tips For Inclusive Postsecondary Education Programs On College Campuses: Peer Mentors’ Perspectives On Access And Inclusion, Laura N. Sarchet, Kristen Love, Martha Mock

Excelsior: Leadership in Teaching and Learning

As inclusive postsecondary education programs have grown and improved towards more campus access for college students labeled with an intellectual disability, peer mentoring is a common model for such programs. Peer mentors from one private institution were asked to describe their experiences and perspectives of campus inclusion after participating in a training program designed to increase their understanding of disability within a social justice lens. Mentors shared the personal and professional benefits of mentoring, for both themselves and for students labeled with an intellectual disability, and noted recommendations for how programs can increase access to college in order to improve …


Scalability Matters: Overcoming Challenges In Instructglm With Similarity-Degree-Based Sampling Jul 2025

Scalability Matters: Overcoming Challenges In Instructglm With Similarity-Degree-Based Sampling

Defensive Publications Series

Large Language Models (LLMs) have demonstrated strong capabilities in various natural language processing tasks; however, their application to graph-related problems remains limited, primarily due to scalability constraints and the absence of dedicated mechanisms for processing graph structures. Existing approaches predominantly integrate LLMs with Graph Neural Networks (GNNs), using GNNs as feature encoders or auxiliary components. However, directly encoding graph structures within LLMs has been underexplored, particularly in the context of large-scale graphs where token limitations hinder effective representation. To address these challenges, we propose SDM-InstructGLM, a novel instruction-tuned Graph Language Model (InstructGLM) framework that enhances scalability and efficiency without relying …


Alphafold Database Debiasing For Robust Inverse Folding Jul 2025

Alphafold Database Debiasing For Robust Inverse Folding

Defensive Publications Series

The AlphaFold Protein Structure Database (AFDB) offers unparalleled structural coverage at near-experimental accuracy, positioning it as a valuable resource for data-driven protein design. However, its direct use in training deep models that are sensitive to fine-grained atomic geometry—such as inverse folding—exposes a critical limitation. Comparative analysis of structural feature distributions reveals that AFDB structures exhibit distinct statistical regularities, reflecting a systematic geometric bias that deviates from the conformational diversity found in experimentally determined structures from the Protein Data Bank (PDB). While AFDB structures are cleaner and more idealized, PDB structures capture the intrinsic variability and physical realism essential for generalization …


Balanced Graphformer: Enhancing Graph Transformers With Localized Training Against Over-Globalization Jul 2025

Balanced Graphformer: Enhancing Graph Transformers With Localized Training Against Over-Globalization

Defensive Publications Series

As Transformers gain traction in graph machine learning, the issue of "over-globalization" has emerged, where their global attention mechanisms excessively emphasize distant vertices, potentially diluting vital local information. This is particularly detrimental in graphs where local neighborhoods hold significant predictive value. Existing methods often lack flexibility in local processing or fail to effectively integrate local and global contexts. This paper introduces BalancedGraphFormer, a novel framework designed to localize graph transformer training. It integrates a dedicated local module with a complementary global module. The local module captures fine-grained neighborhood patterns, while the global module integrates broader context without overshadowing local details. …


Biochar-Based Filtration And Barrier Systems For Urban Stormwater Treatment, Krishna R. Reddy Jul 2025

Biochar-Based Filtration And Barrier Systems For Urban Stormwater Treatment, Krishna R. Reddy

Stormwater Drainage Conference

Conference that deals a wide range of issues dealing with stormwater drainage. Professor Krishna Reddy of University of Illinois Chicago presented an invited talk titled "Biochar-Based Filtration and Barrier Systems for Urban Stormwater Treatment"


A Neuromorphic Spike-Based System For Real-Time Behavioral Anomaly Detection In Saas And Self-Hosted Environments, Marcel Witt Jul 2025

A Neuromorphic Spike-Based System For Real-Time Behavioral Anomaly Detection In Saas And Self-Hosted Environments, Marcel Witt

Defensive Publications Series

This publication introduces NeuraSentry™, a neuromorphic anomaly detection framework inspired by biological spike-based learning and synaptic plasticity. It combines competitive vector detectors, temporal spike traces, and retroactive learning signals to detect evolving behavioral fraud and insider threats in both SaaS and on-premise systems. Key innovations include sparse activation using cosine similarity, HDBSCAN-based meta-neuron clustering, and delayed reward modulation modeled after dopamine and serotonin systems. NeuraSentry delivers adaptive, explainable, and scalable behavioral threat detection, without relying on labeled training data or fixed rules. This work establishes prior art to prevent overly broad patents in the field of neuromorphic security analytics.


Brand Awareness The Case Study Was Applied To Nesma & Partners Contracting Co. Ltd In Saudi Arabia, Soumaya Kaakour, Pierre Mouawad Jul 2025

Brand Awareness The Case Study Was Applied To Nesma & Partners Contracting Co. Ltd In Saudi Arabia, Soumaya Kaakour, Pierre Mouawad

Al Jinan الجنان

This paper examines the factors affecting brand awareness in Saudi Arabia Nesma & Partners Contracting Co. Ltd. An electronic survey was distributed to 203 employees. The results indicated a positive correlation between credibility and brand awareness, while a negative correlation between the following variables (social media, influencer, E-wom) and brand awareness. These results imply that companies like Nesma & partners should not rely on social media, influencers, and E-wom to reach brand awareness. Future research is needed to investigate more factors affecting brand awareness in construction companies


مدى تضمين أولوية البيئة والموارد الطبيعية برؤية عُمان ٢٠٤٠ في كتب الدراسات الاجتماعية للصفوف (٥-١٠). The Extent Of The Inclusion Of Environment Priority And Natural Resources In Oman Vision 2024in Social Studies Textbooks For Grades (5-10)., سيف ناصر المعمري, وفاء محمد معوض عبد العال Jul 2025

مدى تضمين أولوية البيئة والموارد الطبيعية برؤية عُمان ٢٠٤٠ في كتب الدراسات الاجتماعية للصفوف (٥-١٠). The Extent Of The Inclusion Of Environment Priority And Natural Resources In Oman Vision 2024in Social Studies Textbooks For Grades (5-10)., سيف ناصر المعمري, وفاء محمد معوض عبد العال

Association of Arab Universities Journal for Education and Psychology

هدفت الدراسة إلى استقصاء مدى تضمين محتوى مناهج الدراسات الاجتماعية للصفوف (5-10) في سلطنة عمان لأولوية البيئة والموارد الطبيعية التي تضمنتها رؤية عمان ٢٠٤٠؛ ولتحقيق ذلك اعتمدت الدراسة المنهج الوصفي في تحليل مناهج الدراسات الاجتماعية للصفوف من (5-10)، ولجمع بيانات الدراسة تم استخدام بطاقة تحليل تضمنت الأهداف السبعة للأولوية المذكورة، التي تشمل (26) مؤشرًا بجانب، خمس وحدات تحليل، استخلصها الباحثون وهي تمثل البنية المعرفية للمحتوى كالأمثلة، والخصائص أو السمات والإشكاليات، والإحصاءات. وخلصت نتائج الدراسة عن تضمن الأهداف السبعة لأولوية البيئة والموارد الطبيعية في مناهج الدراسات الاجتماعية للصفوف (٥-١0)، وقد تصدر الهدف السادس "طاقة متجدِّدة ومصادر متنوعة وترشيد الاستهلاك لتحقيق أَمْنِ …


Respiratory Recovery Via Endogenous And Electrical Stimulation-Induced Mechanisms Following Cervical Spinal Cord Injury, Taylor C. Holmes Jul 2025

Respiratory Recovery Via Endogenous And Electrical Stimulation-Induced Mechanisms Following Cervical Spinal Cord Injury, Taylor C. Holmes

Dissertations (1934 -)

Breathing is a complex neuromuscular behavior vital for the maintenance of life. Cervical spinal cord injury (cSCI) disrupts descending respiratory motor drive and can lead to profound breathing impairments. While a limited, endogenous recovery of respiratory function has been well described following cSCI, this work has predominantly utilized single sex investigations. Given that relatively few treatment options exist to address this respiratory insufficiency, a more complete characterization of respiratory recovery post-cSCI is necessary for the development and evaluation of rehabilitative protocols. Diaphragm pacing (DP) is an emerging clinical intervention that utilizes electrical stimulation of the diaphragm muscle to combat the …


Illuminating Trauma & Resilience In Educational Spaces: Expanding Narratives To Promote Historical And Critical Civic Empathy At Little Rock Central High School National Historic Site, Chakakuan Johnson, Linda Nance, Byron Witherspoon Jul 2025

Illuminating Trauma & Resilience In Educational Spaces: Expanding Narratives To Promote Historical And Critical Civic Empathy At Little Rock Central High School National Historic Site, Chakakuan Johnson, Linda Nance, Byron Witherspoon

Dissertations

Abstract

The 1957 desegregation crisis at Little Rock Central High School marked a defining moment in the Civil Rights Movement and continues to symbolize the broader struggle for racial equality. This dissertation examines equity in educational spaces through a four-truth lens that was first articulated by the South African Truth and Reconciliation Commission and explores forensic, personal, social, and healing truth. Using Little Rock Central High School National Historic Site (CHSC) and park interpretation as the focal point, our qualitative research study used reflexive thematic analysis to examine oral interviews, onsite observations, and various documents and artifacts, and to illuminate …


Complete Genome Sequence Of Staphylococcus Haemolyticus Umb6531b, Isolated From A Perineal Swab, Alex Kula, Olive Kolar, Karolina Gilewicz, Zainab Qureshi, Anmol Singh, Alan J. Wolfe, Catherine Putonti Jul 2025

Complete Genome Sequence Of Staphylococcus Haemolyticus Umb6531b, Isolated From A Perineal Swab, Alex Kula, Olive Kolar, Karolina Gilewicz, Zainab Qureshi, Anmol Singh, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

Staphylococcus haemolyticus UMB6531B was isolated from a perineal swab of a female with overactive bladder symptoms and sequenced to better characterize opportunistic pathogens of the female urogenital tract. Here, we present the complete genome sequence, which includes the chromosome as well as two complete plasmid sequences.


Relationship Between Indulgent Parenting, Household Composition, And Parental Efficacy In Managing Adolescents' Smartphone Use, Bernice Cook Jul 2025

Relationship Between Indulgent Parenting, Household Composition, And Parental Efficacy In Managing Adolescents' Smartphone Use, Bernice Cook

Walden Dissertations and Doctoral Studies

Smartphones have become an integral part of society, resulting in increased adolescent dependence on smartphone applications. This dependence poses challenges for parents in managing the risk of problematic smartphone use among adolescents aged 11-17 years old. Rapid technological advancements have significantly reshaped parenting practices, necessitating greater adaptability and impacting adolescent development. Guided by Bandura’s self-efficacy theory, this correlational study examines how indulgent parenting and household composition, including demographic variables such as race, gender, education, employment, and income, predict parental self-efficacy in managing adolescent smartphone use. A convenience sample of 238 U.S. parents, with at least one adolescent aged 11-17 years, …


Representation And Visualization Of Multivariate Sensory Time Series Data, Ismail Uysal, Alla Abdella Jul 2025

Representation And Visualization Of Multivariate Sensory Time Series Data, Ismail Uysal, Alla Abdella

USF Patents

In accordance with some embodiments, systems, methods, and media for processing and representing multivariate sensor information gathered from multiple sources are provided. In some embodiments, the method comprises: receiving a data sequences from respective sources; identifying a shortest data sequence that corresponds to a first interval; calculating, for pairs of data sequences, a similarity value over the first interval; forming a first segment of a representative data sequence that is a weighted combination of the data sequences over the first interval based on similarity values associated with the data sequences; truncating at least a subset of data sequences to exclude …


Total Synthesis And Biological Activity Of "Carbamorphine": O-To-Ch2 Replacement In The E-Ring Of The Morphine Core Structure, Sota Akiyama, Rohini S Ople, Alexander Kremsmair, Nokomis Ramos-Gonzalez, Thomas Nedungadan, Brandon J Kennedy, Kevin Appourchaux, Shainnel O Eans, Bowen A Tsai, Christina Kraml, Xi-Ping Huang, Jay P Mclaughlin, Susruta Majumdar, Richmond Sarpong Jul 2025

Total Synthesis And Biological Activity Of "Carbamorphine": O-To-Ch2 Replacement In The E-Ring Of The Morphine Core Structure, Sota Akiyama, Rohini S Ople, Alexander Kremsmair, Nokomis Ramos-Gonzalez, Thomas Nedungadan, Brandon J Kennedy, Kevin Appourchaux, Shainnel O Eans, Bowen A Tsai, Christina Kraml, Xi-Ping Huang, Jay P Mclaughlin, Susruta Majumdar, Richmond Sarpong

2020-Current year OA Pubs

Morphine is a µ-opioid receptor (MOR) agonist and potent analgesic. However, it displays several side effects including respiratory depression and addiction. Here, we show that a single heavy atom replacement in the morphine core structure (O to CH


Violence Towards Ems, Briana Moffat Jul 2025

Violence Towards Ems, Briana Moffat

AJiC Fact Sheets

This factsheet examines violence towards Emergency Medical Services (EMS) responders as documented in existing research literature, tying into Alaska's Crisis Response Team models.


Zoo Visitors Learn By Observing Olive Baboons (Papio Anubis) Participate In Cognitive Research Or Engage In Natural Behaviors, Anna Sofia Hege Jul 2025

Zoo Visitors Learn By Observing Olive Baboons (Papio Anubis) Participate In Cognitive Research Or Engage In Natural Behaviors, Anna Sofia Hege

Theses

I conducted two experiments at the baboon exhibit at the Seneca Park Zoo in Rochester, New York to measure attitudes and actual knowledge in children and adults, as well as perceived learning in adults. I also recorded caregiver-child conversations in the presence and absence of live research. Experiment 1 included 150 adult participants, and Experiment 2 included 18 caregiver-child dyads. In each experiment, the research on-scientist present and research on-scientist absent group watched the baboons engage with live cognitive research while the research off-scientist present and research off-scientist absent group watched the baboons carry out their natural behaviors. A scientist …


Beliefs About The Causes And Treatment Of Common Mental Illnesses And Suicidality In Rural Uganda, Yang Jae Lee, Rita Mbabazi, Ondine Jevremov, Shakira Nakaweesi, Ella Brodey, Jason Wykoff, Roshan Sivakumar, Rauben Kazungu, Ibrahim Ssekalo, Robert Rosenheck, Alexander C Tsai Jul 2025

Beliefs About The Causes And Treatment Of Common Mental Illnesses And Suicidality In Rural Uganda, Yang Jae Lee, Rita Mbabazi, Ondine Jevremov, Shakira Nakaweesi, Ella Brodey, Jason Wykoff, Roshan Sivakumar, Rauben Kazungu, Ibrahim Ssekalo, Robert Rosenheck, Alexander C Tsai

2020-Current year OA Pubs

BACKGROUND: Mental illnesses constitute a large and escalating portion of the global burden of disease, particularly in low- and middle-income countries like Uganda. Understanding community perceptions towards mental illness is crucial for developing effective interventions.

AIMS: To explore beliefs about the perceived causes and treatment of common mental illnesses (depression, anxiety, alcohol use disorder) and suicidality in rural eastern Uganda.

METHOD: Qualitative study using 31 in-depth interviews and 4 focus group discussions with healthcare workers, community health workers, community leaders and general community members in Buyende District, Uganda. Vignettes were used to depict mental illnesses to elicit perceptions, and data …


Involvement Of Microglia In Retinal Ganglion Cell Injury Induced By Iop Elevation In A Rat Ex Vivo Acute Glaucoma Model, Taimu Sato, Makoto Ishikawa, Yukitoshi Izumi, Naoya Shibata, Kota Sato, Michiko Ohno-Oishi, Hiroshi Tawarayama, Hiroshi Kunikata, Charles F Zorumski, Toru Nakazawa Jul 2025

Involvement Of Microglia In Retinal Ganglion Cell Injury Induced By Iop Elevation In A Rat Ex Vivo Acute Glaucoma Model, Taimu Sato, Makoto Ishikawa, Yukitoshi Izumi, Naoya Shibata, Kota Sato, Michiko Ohno-Oishi, Hiroshi Tawarayama, Hiroshi Kunikata, Charles F Zorumski, Toru Nakazawa

2020-Current year OA Pubs

No abstract provided.


Mtor Signaling Regulates The Development Of Airway Mucous Cell Metaplasia Associated With Severe Asthma, Katrina M. Kudrna, Luis F. Vilches, Evan M. Eilers, Shailendra K. Maurya, Steven L. Brody, Amjad Horani, Kristina L. Bailey, Todd A. Wyatt, John D. Dickinson Jul 2025

Mtor Signaling Regulates The Development Of Airway Mucous Cell Metaplasia Associated With Severe Asthma, Katrina M. Kudrna, Luis F. Vilches, Evan M. Eilers, Shailendra K. Maurya, Steven L. Brody, Amjad Horani, Kristina L. Bailey, Todd A. Wyatt, John D. Dickinson

2020-Current year OA Pubs

In asthma, airway epithelial remodeling is characterized by aberrant goblet cell metaplastic differentiation accompanied by epithelial cell hyperplasia and hypertrophy. These pathologic features in severe asthma indicate a loss of control of proliferation, cell size, differentiation, and migration. MTOR is a highly conserved pathway that regulates protein synthesis, cell size, and proliferation. We hypothesized that the balance between MTOR and autophagy regulates mucous cell metaplasia. Airways from individuals with severe asthma showed increased MTOR signaling by RPS6 phosphorylation, which was reproduced using an IL-13-activated model of primary human airway epithelial cells (hAEC). MTOR inhibition by rapamycin led to a decrease …


Cord Blood Proteomics Identifies Biomarkers Of Early-Onset Neonatal Sepsis, Leena B. Mithal, Mark E. Becker, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Aspen Kremer, Surya Pandey, Nicola Lancki, Yawei Li, Yuan Luo, William Grobman, Denise Scholtens, Karen K. Mestan, Patrick C. Seed, Judd F. Hultquist Jul 2025

Cord Blood Proteomics Identifies Biomarkers Of Early-Onset Neonatal Sepsis, Leena B. Mithal, Mark E. Becker, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Aspen Kremer, Surya Pandey, Nicola Lancki, Yawei Li, Yuan Luo, William Grobman, Denise Scholtens, Karen K. Mestan, Patrick C. Seed, Judd F. Hultquist

2020-Current year OA Pubs

BACKGROUNDSymptoms of early-onset neonatal sepsis (EOS) in preterm infants are nonspecific and overlap with normal postnatal physiological adaptations and noninfectious pathologies. This clinical uncertainty and the lack of reliable EOS diagnostics results in liberal use of antibiotics in the first days to weeks of life, leading to increased risk of antibiotic-related morbidities in infants who do not have an invasive infection. METHODSTo identify potential biomarkers for EOS in newborn infants, we used unlabeled tandem mass spectrometry proteomics to identify differentially abundant proteins in the umbilical cord blood of infants with and without culture-confirmed EOS. Proteins were then confirmed using immunoassay, …


Polymorphic Α-Glucans As Structural Scaffolds In Cryptococcus Cell Walls For Chitin, Capsule, And Melanin: Insights From 13c And 1h Solid-State Nmr, Ankur Ankur, Jayasubba Reddy Yarava, Isha Gautam, Faith J. Scott, Frederic Mentink-Vigier, Christine Chrissian, Li Xie, Dibakar Roy, Ruth E. Stark, Tamara L. Doering, Ping Wang, Tuo Wang Jul 2025

Polymorphic Α-Glucans As Structural Scaffolds In Cryptococcus Cell Walls For Chitin, Capsule, And Melanin: Insights From 13c And 1h Solid-State Nmr, Ankur Ankur, Jayasubba Reddy Yarava, Isha Gautam, Faith J. Scott, Frederic Mentink-Vigier, Christine Chrissian, Li Xie, Dibakar Roy, Ruth E. Stark, Tamara L. Doering, Ping Wang, Tuo Wang

School of Graduate Studies Faculty Publications

Cryptococcus species are major fungal pathogens responsible for life-threatening infections in approximately a million individuals globally each year, with alarmingly high mortality rates. These fungi are distinguished by a distinctive cell wall architecture further reinforced by two virulence-associated layers, melanin and capsule, rendering them insensitive to antifungal agents targeting the cell wall, such as echinocandins. The molecular interplay between these three biomolecular layers remains poorly understood. Here we employ solid-state NMR spectroscopy to examine intact cells of both wild-type and capsule-deficient strains of C. neoformans, along with melanized cells. High-resolution 13C and 1H data revealed five distinct structural forms of …


The Role Of Self-Reported Health Ratings In Identifying Hospitalization Risk Among Older Adults: An Integrated Review And Secondary Analyses Of Medicare Claims Data, Mary B. Prybylo Jul 2025

The Role Of Self-Reported Health Ratings In Identifying Hospitalization Risk Among Older Adults: An Integrated Review And Secondary Analyses Of Medicare Claims Data, Mary B. Prybylo

MUSC Theses and Dissertations

Purpose: This study examined how Self-Reported Health (ratings), a person’s own evaluation of their overall health, relates to hospital admissions and emergency department utilization. It further assessed the extent to which demographic characteristics, Risk Adjustment Factor (RAF) scores (used to estimate healthcare expenditures based on clinical complexity), and the number of chronic conditions influence SRH rating and the likelihood of hospitalization.

Problem and Aim: The growing population of older adults places greater demands on healthcare services, leading to increased financial strain and a need for improved care strategies. Primary care teams, particularly those managing older adults, require effective assessment …


Elucidation Of A Role In Biofilm Production For The Tyrosine Catabolism Pathway In Vibrio Cholerae And Analysis Of Reversible Phase Variation In Vibrio Vulnificus, Aheli S. Mukerji Jul 2025

Elucidation Of A Role In Biofilm Production For The Tyrosine Catabolism Pathway In Vibrio Cholerae And Analysis Of Reversible Phase Variation In Vibrio Vulnificus, Aheli S. Mukerji

LSU Doctoral Dissertations

Biofilms produced by the cholera pathogen Vibrio cholerae not only enhance its ability to survive in the environment but also allow pathogenic success of the bacterium. This organism also undergoes phase variation, switching between smooth and rugose colonial phenotypes, the latter forming much more vibrio polysaccharide (VPS) resulting in more robust biofilms and subsequently having an increased level of persistence. In a previous study, many genes were found to be upregulated in the transition from the smooth to the rugose phenotype. Here, several of these upregulated genes were investigated for their potential role in biofilm production, and an additional gene, …


Magnetic Field Enabled Assembly And Propulsion Of Colloidal Particles In A Magnetic Medium, Hashir M. Gauri Jul 2025

Magnetic Field Enabled Assembly And Propulsion Of Colloidal Particles In A Magnetic Medium, Hashir M. Gauri

LSU Doctoral Dissertations

Colloidal particles are nano/micro meter-sized particles dispersed in a fluid medium and serve as diverse building blocks for assembling complex structures. The ease of tunability of the shape, size, and interparticle interactions of colloidal particles facilitates their assembly into rich structures and phases that mirror the assembly process of atomic systems. Often regarded as "big atoms" colloidal particles provide an ideal model system for investigating complex phenomena in condensed matter, such as crystallization and nucleation. While the assembly of colloids under thermodynamic equilibrium has been extensively studied, recent interest has shifted toward exploring colloids in non-equilibrium conditions to create dynamic …


Str Analysis Performance Comparison For Two Capillary Electrophoresis Instruments: The Seqstudio And The 3500 Genetic Analyzers, Yana Leichyk Jul 2025

Str Analysis Performance Comparison For Two Capillary Electrophoresis Instruments: The Seqstudio And The 3500 Genetic Analyzers, Yana Leichyk

Student Theses

This study compares the performance of two capillary electrophoresis instruments—the SeqStudio™ Genetic Analyzer and the 3500™ Genetic Analyzer—for forensic short tandem repeat (STR) analysis. Using the GlobalFiler STR kit and certified reference material (SRM 2391d), five key performance metrics were evaluated: sizing precision, signal reproducibility, detection sensitivity, mixture resolution, and overload tolerance. STR profiles were generated from single-source and mixture samples with DNA inputs ranging from 500 pg to 15.6 pg. Both instruments met the < 0.15 bp sizing precision requirement for forensic casework. Signal reproducibility tests showed that the SeqStudio often produced higher average RFU values, but with greater variability, while the 3500 demonstrated more stable signal performance across days and samples. Mixture detection was effective on both platforms up to 1:10 ratios. Dropout of minor alleles began to appear at 1:20 ratios, especially in green and yellow dye channels, on both instruments. Sensitivity studies confirmed full profile recovery down to 62.5 pg, with increasing allelic and locus dropout at lower inputs. Enhanced injection voltage (1.5 kV) did not improve low-template performance. In overload testing (1–5 ng input), the 3500 maintained a consistent signal output, while the SeqStudio exhibited signal suppression at 5 ng, likely due to internal normalization. The SeqStudio exhibited better spectral overlap compensation, with fewer occurrences of spectral bleed-through artifacts. These findings support the use of both platforms in forensic casework, while emphasizing the importance of platform-specific calibration and analytical threshold settings for optimal performance.


The Effects Of Rubber Dam Clamps On Zirconia Crown Restorations, Haley D. Kessler, Albert F. Mcmullen Iii, Hunter Kortum, Edwin Kee, Thomas E. Lallier Jul 2025

The Effects Of Rubber Dam Clamps On Zirconia Crown Restorations, Haley D. Kessler, Albert F. Mcmullen Iii, Hunter Kortum, Edwin Kee, Thomas E. Lallier

School of Dentistry Faculty Publications

Rubber dam isolation is crucial in providing sterility and a controlled environment when performing root canal therapy. Rubber dam clamps have been controversial due to their rigidity and composition, which is thought to cause damage to zirconia full coverage crowns. This study evaluated three types of zirconia crowns anterior 5Y, premolar 4Y, and molar 3Y to assess their resistance to damage from rubber dam clamps. Of the 30 total zirconia crowns that were tested for damage following the usage of rubber dam clamps, no fractures or chips were observed. There was no significant difference between the negative control group, and …


Genome-Wide Characterization Of Vdac Gene Family In Soybean (Glycine Max L.) And In Silico Expression Profiling In Response To Drought And Salt Stress, Muhammad Muneeb Ullah, Muqadas Aleem, Mudassar Muhammad Iqbal, Ainong Shi Jul 2025

Genome-Wide Characterization Of Vdac Gene Family In Soybean (Glycine Max L.) And In Silico Expression Profiling In Response To Drought And Salt Stress, Muhammad Muneeb Ullah, Muqadas Aleem, Mudassar Muhammad Iqbal, Ainong Shi

Horticulture Faculty Publications and Presentations

Soybean (Glycine max L.) is grown worldwide to obtain edible oil, livestock feed, and biodiesel. However, drought and salt stress are becoming serious challenges to global soybean cultivation as they retard the growth of soybean plants and cause significant yield losses. Voltage-dependent anion-selective channel (VDAC) proteins are well-known for their role in drought and salt tolerance in crop plants. In this study, we identified 111 putative VDAC genes randomly distributed in genomes of 14 plant species, including cultivated soybean (Glycine max) and wild soybean (Glycine soja). The comparative phylogenetic studies classified these genes into six different clades and found the …


Strategic Innovation In The Dod Fy 2026 Rdte Budget: Leveraging Disruptive Technologies For Deterrence, Defense, And Command And Control, James Giordano Jul 2025

Strategic Innovation In The Dod Fy 2026 Rdte Budget: Leveraging Disruptive Technologies For Deterrence, Defense, And Command And Control, James Giordano

Strategic Insights

This commentary analyzes the Department of Defense FY 2026 Research, Development, Test, and Evaluation (RDTE) budget and its strategic emphasis on convergent disruptive technologies. The author argues that expanded investment in artificial intelligence, quantum systems, hypersonics, and space capabilities reflects a doctrinal shift toward integrated, multi-domain deterrence and AI-enabled command and control. These technologies are described not merely as tools, but as operational paradigms reshaping force posture, battlefield tempo, and cross-domain warfare. The article also addresses ethical oversight, human–machine teaming, quantum resilience, hypersonic navigation, and the biological and cognitive implications of technological convergence. It concludes that sustained advantage will require …


The Effect Of Temperature For Producing Thayer-Martin Agar Media Using Sheep Blood On Neisseria Gonorrhoeae Growth With Various Inoculums, Ika Ningsih, Kayla Adyapratista Sumadiyo Jul 2025

The Effect Of Temperature For Producing Thayer-Martin Agar Media Using Sheep Blood On Neisseria Gonorrhoeae Growth With Various Inoculums, Ika Ningsih, Kayla Adyapratista Sumadiyo

Indonesian Journal of Medical Chemistry and Bioinformatics

Neisseria gonorrhoeae is a Gram-negative bacterium in the form of diplococci that infects mucous membranes through direct inoculation, is fastidious, and requires special media for growth because it is susceptible to heating and dryness, so it cannot survive long outside its host. Thayer-Martin agar media is a selective culture medium for the diagnosis of Neisseria gonorrhoeae bacterial infections enriched with sheep blood. The purpose of this study was to determine the optimum temperature for various temperature variations of making Thayer-Martin agar when mixing with sheep blood, compared to the temperature according to the manufacturer's procedure. Determining this ideal temperature may …