Digital Commons Network^™

Metabolic And Barrier Function In Response To Β-Caryophyllene In Intestinal Epithelial Cells, Hannah Scroggins

Theses and Dissertations--Animal and Food Sciences

Butyrate, a short-chain fatty acid, regulates cellular metabolism and energy status in intestinal epithelial cells. β-caryophyllene (BCP) is a plant-derived compound that may provide advantageous effects on intestinal barrier function and nutrient utilization. The goal of this thesis was to investigate the effects of BCP on butyrate utilization and metabolism in intestinal epithelial cells. Throughout this thesis, Caco-2 cells in hanging inserts in multi-well plates were used as a model for the intestinal barrier. One study was conducted to investigate the effect of BCP on butyrate utilization and barrier function in intestinal epithelial cells. A second study aimed to elucidate …

Comparison Of Sheep And Cattle Rumen Microbiological And Physiological Responses To An Abrupt Transition From A High-Forage To A High-Concentrate Diet, Katherine Purvis

Theses and Dissertations--Animal and Food Sciences

Sheep and cattle are often used interchangeably due to having the same gastrointestinal anatomy; however literature directly comparing the two species is minimal. Previous in vitro studies have pointed towards potential species differences in rumen carbohydrate utilization and acidosis susceptibility. The objective of this study was to evaluate in vivo microbiological and physiological responses of wethers and steers when abruptly transitioned from a high-forage to a high-concentrate diet. We hypothesized there are differences between species in response to abrupt dietary transition with respect to intake, rumen microbiology, and the rumen environment. Individually housed, rumen cannulated purebred Polypay wethers (n = …

Red Palm Oil Mitigates Vitamin A Deficiency In Parotid Salivary Glands An Animal Study, Sara Elbanna, Mohamed Mansy, Mohamed Shamel, Mahmoud Al Ankily, Caroline Maged Massieh

Dentistry

No abstract provided.

Epidemiology Of Recurrent Herpes Labialis Among Dentistry Students: A Cross-Sectional Survey In Egypt, Sara Abdelwahed, Dalia Ghalwash, Al Hassan Diab

Dentistry

Aim: Recurrent herpes labialis (RHL) is a common viral infection with significant psychosocial and clinical implications. Dental students are particularly vulnerable due to stress and frequent patient contact, yet data on their epidemiology in Egyptian cohorts are scarce. The study aimed to determine the prevalence, recurrence patterns, and associated risk factors of RHL among dentistry students in Egypt. Materials and Methods: A cross-sectional survey was conducted among 559 dentistry students at the British University in Egypt. A structured, self-administered questionnaire captured sociodemographic data, history of RHL episodes, frequency, severity, and triggering factors. Data were analyzed using descriptive statistics and Chi-square …

Prevalence And Impact Of Xerostomia On Quality Of Life: A Clinical-Based Cross-Sectional Study In Egypt, Dalia Ghalwash, Ayman Elgawish, Asmaa Abou-Bakr

Dentistry

Background The current investigation aimed to assess the prevalence of xerostomia, its relation to risk factors, and its impact on the quality of life among a sample of the Egyptian population.

Methods This cross‑sectional study collected data on the occurrence of xerostomia and risk factors from 1220subjects in several Egyptian governorates, including sex, age, smoking, systemic illness, and medications. Subjective and objective dry mouth scores, taste disturbances, burning sensations, and their impact on quality of life were assessed.

Results Xerostomia was estimated to involve 49.6% of the studied population. It was found to increase with ageand was substantially higher amongst …

An Exploratory Approach To Understanding Assessment Errors On Measures Of Executive Functioning, Gurjot Mondair

PCOM Psychology Dissertations

The global risk of dementia due to longer lifespans and increased medical interventions necessitates accurate diagnosis of cognitive decline. Thus, the utilization of neuropsychological testing to diagnose disorders of cognitive decline should seek to ascertain multiple data, including success/failure of cognitive tasks and evaluation of error patterns. The purpose of this study was to examine the frequency of executive function (EF) errors across diagnoses of cognitive decline (age-related cognitive decline [ARCD], mild cognitive impairment [MCI], vascular dementia [VaD], frontotemporal dementia [FTD], Lewy body dementia [LBD], and Alzheimer’s disease [AD]) and to examine whether the specific types of EF errors (intrusion, …

Phytochemical And Nutritional Composition Of Vernonia Amygdalina: Antioxidant, Antidiabetic Efficacy, And Hematological Benefits, Hassan A. Adewuyi, Messiah Atapia, Emmanuel Ochonung, Sakariyau A. Waheed, Adebimpe H. Oluwatoyin, Chizoba V. Obunadike, Adeleye A. Edema, Samad Hussein, Usman A. Mohammed, Kevin L. Sebastine, Tolulope O. Jaiyeola

Chemistry & Biochemistry Faculty Publications

Vernonia amygdalina, a traditionally used medicinal plant, has been purported to possess health-promoting properties. The aim of this study is to investigate the phytochemical and nutritional composition of V. amygdalina, evaluate its antioxidant and antidiabetic efficacy, and assess its hematological benefits. Phytochemical screening, proximate analysis, antioxidant assays (DPPH, ABTS), antidiabetic evaluations in treptozotocin induced diabetic rats, and hematological assessments were conducted according to standard protocol. V. amygdalina exhibited a rich phytochemical profile, comprising flavonoids, phenolic acids, and terpenoids, alongside significant antioxidant activity (IC50 = 12.5 μg/mL) and complete source of protein. Proximate analysis revealed high protein (21.1%) and …

Selective Nutrient Incorporation May Underestimate Heterotrophy Of A Mixotrophic Reef-Building Coral, Connor R. Love, Marleen Stuhr, Michael D. Fox, Veronica Z. Radice, Maoz Fine, Kelton W. Mcmahon, David L. Valentine

Biological Sciences Faculty Publications

Mixotrophic reef-building corals acquire nutrition via photosynthate translocation from endosymbiotic microalgae and by heterotrophic prey/particle capture. Heterotrophy promotes resistance to, and recovery from, environmental stress, but quantifying coral heterotrophy remains difficult due to complex resource exchanges within the coral holobiont. We interrogated the response of multiple biomarkers to coral heterotrophy using fatty acid profiling and stable isotope analysis of Stylophora pistillata grown along a controlled feeding gradient from pure autotrophy to pure heterotrophy. We found that fatty acids and nitrogen were effectively incorporated into both coral host and symbiont tissues, while carbon, which is the primary target for conventional heterotrophy …

Novel Insights Into Beta Cell Er Stress Chop And It's Role In Hfpef Development, Balaji Srinivas, Paula Fortuno, Hongmei Peng, Jiang Xu, Hamid Suhail, Hani N. Sabbah, Nour-Eddine Rhaleb, Khalid Matrougui

Department of Physiological Sciences Faculty Publications

Introduction: Heart failure with preserved ejection fraction (HFpEF) is a multifactorial cardiovascular disorder characterized by diastolic dysfunction and often associated with hypertension and metabolic disturbances. We aimed to determine the inter-relationship between C/EBP homologous protein (CHOP) in b-cells and HFpEF development.

Methods: Eight-week-old male mice b-cell^flox/flox and b-cell^CHOP-/- were randomly divided into four groups: control b-cell^flox/flox and b-cell^CHOP-/- mice subjected to standard diet and water. b -cell^flox/flox and b-cell^CHOP-/- mice fed a high-fat diet (HFD) and L-NAME (0.5 g/L) for five weeks. A comprehensive cardiovascular, metabolic, and histological evaluation was conducted.

Results: Following …

Marked By Valor: The “Lost” History Of The 6th United States Colored Troops, Heavy Artillery, Daniel William O’Sullivan

CGU Theses & Dissertations

“Marked by Valor: The ‘Lost’ History of the 6 th U.S.C.T., Heavy Artillery,” argues that the camaraderie of having been a Black Union soldier solidified a sub-culture of Black veterans and their families in Natchez, Mississippi, that cohered throughout the Reconstruction period using the tools and the affiliations first gained in slavery and strengthened during the soldiers’ time in the army. Underlying this narrative is an interpretation of Southern history that maintains that we cannot understand the events of the postwar period—not only for Black veterans, but to some extent all freed people—if we do not understand all that came …

Indigenous Vs Western Land Management Strategies In The Pacific Islands, Catherine Farley

Pomona Senior Theses

This paper explores the critical role of sustainable land management in the Pacific Islands, focusing on its intersection with climate change mitigation, biodiversity conservation, and cultural preservation. Indigenous land management practices, shaped over generations, are integral in maintaining ecosystem services such as carbon sequestration, soil fertility, clean water, and coastal protection. These methods not only enhance resilience to climate change but also preserve species crucial for food security and cultural practices. By comparing traditional and Western land management strategies, this research suggests ways to integrate modern technology with indigenous knowledge to improve adaptive capacity. The paper addresses the gap in …

“Nice To See You”: Addressing Plant Awareness Disparity With Locally Specific Ecological And Cultural Plant Education, Cecilia Muecke

Pomona Senior Theses

Plants form the basis of life on Earth. However, due to the phenomenon of plant awareness disparity, a self-perpetuating cycle whereby plants are overlooked on an individual and global level ensues. Lack of plant awareness leads to a lessened emphasis on plants in sustainability and conservation as well as biology education, resulting in negative impacts on biodiversity and food security. The severity of plant awareness disparity is dependent on cultural context, and Indigenous and/or traditional societies are less likely to experience plant awareness disparity because of they are typically more connected to plants for their everyday needs. Native plants are …

Rwanda's Natural Remedies: A Fresh Look At The Fight Against Malaria, Leandre Nsabimana Ndisanze

Pomona Senior Theses

Malaria remains one of the most devastating parasitic diseases globally, disproportionately affecting sub-Saharan Africa, where Rwanda continues to face high transmission rates and rising resistance to conventional interventions. Despite decades of control efforts, the emergence of drug-resistant Plasmodium falciparum and insecticide-resistant Anopheles mosquitoes threatens to reverse recent gains. This research responds to the urgent need for sustainable and culturally relevant alternatives by exploring the therapeutic potential of Rwandan traditional medicinal plants. These indigenous remedies, long used by local healers, offer an underexplored reservoir of bioactive compounds that may provide the basis for novel antimalarial drugs.

The central hypothesis of this …

Creating A Short-Form Label Avoidance Measure: A Psychometric, Julia Johanna Cameron

Graduate Student Theses, Dissertations, & Professional Papers

Stigma is a commonly reported barrier to receiving treatment for mental health concerns. One aspect of stigma, label avoidance, specifically addresses the stigma involved when individuals deny their status as having a mental illness and avoid institutions that may mark them as someone with a mental illness. Despite the importance of label avoidance for understanding treatment seeking, there does not currently exist a psychometrically sound measure of label avoidance. In order to address this gap, the present study used a revised and shortened form of a preliminary measure of label avoidance, the LAM-16, to collect psychometric data over two time …

Budget Recommendations Fy2025-26, Tennessee. Commission On Children And Youth.

Annual Report

No abstract provided.

Florida Scrub Is Nuts (And Drupes): Fruit Production And Consumption In Florida’S Fire-Prone, Xeric Uplands, Warren G. Abrahamson Ii

Faculty Journal Articles

This is a story about how plant size, fire, and climate affect fruit and nut production (i.e., mast) in Florida’s fire-prone, xeric uplands and the importance of mast as food for wildlife. To set the stage, let’s first explore the primary mast-producing plants of Florida’s xeric uplands: oaks, hickory, and palmettos.

Evaluation Of Lyte’S Pilot Health And Wellness Coach Training Program, Lauren Allyson Von Lawn

CGU Theses & Dissertations

Breast cancer survivorship presents ongoing physical, emotional, and social challenges that often extend beyond clinical treatment. While survival rates continue to improve, many survivors lack adequate post-treatment support, particularly in underserved communities. The Living Your Truth Empowered (LYTE) Foundation developed and piloted a Health and Wellness Coach Training Program to address these gaps by preparing individuals—including survivors, advocates, and community members—to provide evidence-based, holistic support. This 16-week cohort-based program, funded through a City of Hope Healthy Living Community Benefits Grant, integrates the National Board of Health and Wellness Coaching (NBHWC) standards with curriculum content focused on: behavior change, cultural humility, …

Hslic Annual Report Fy2024-25, University Of New Mexico Health Sciences Library And Informatics Center

HSLIC Annual Reports

Annual report for FY 2024-2025.

Using Machine Learning To Investigate Weather Impacts On Crop Yield For Probabilistic, Climate-Informed Predictive Crop Breeding, Levi Newell

Theses and Dissertations

As the world’s population continues to grow, the importance of food security willonly continue to increase, with some estimates requiring a global increase in food production between 59 and 98% by 2050. The agriculture industry is also a crucial economic driver, with the industry supporting 20% of the state of North Dakota’s workforce, and with a total valuation of $41.3 billion. The economic importance of this industry and the challenges of future growth prompt a need for data driven decision making into the future, particularly with predictive crop breeding. This is the method by which crops are developed that are …

Facilitated Group Care For Maternal And Child Health Model Fidelity: A Scoping Review, Ashley Gresh, Phoebe Parker, Anne Batchelder, Jalana Lazar, Christina X. Marea, Camilla Bjelland, Rohan D. Jeremiah, Giovanna Cristina Machado-Kayzuka, Hayden Geibel, Dhruvi R. Patel, Esnath Kapito, Kathleen F. Norr, Crystal L. Patil

Department of Pediatrics Faculty Publications

Group care is a transformative model of prenatal, postnatal, and well-child care. The Centering-based group care model has three core components: health care, interactive learning, and community building. It has been implemented in 33 countries with associated improved maternal and child health outcomes. Maintaining fidelity to the model is essential for its effectiveness. However, to date no standardised measure of fidelity to the group care model exists. This review aimed to explore how fidelity is measured in group care and identify common themes to understand what is essential to maintain fidelity. We used the scoping review framework by Arksey & …

Multi-Locas Gwas Mapping And Candidate Gene Analysis Of Anticancer Peptide Lunasin In Soybean (Glycine Max L. Merr), Rikki Locklear, Jennifer Kusumah, Layla Rashad, Felicia Lugaro, Sonia Viera, Nathan Kipyego, Faith Kipkosgei, Daisy Jerop, Shirley Jacquet, Mythy Addelmajid Kassem, Jiazheng Yuan, Elvira De Mejia, Rouf Mian

Biological Sciences Faculty Publications

Soybean (Glycine max) peptide lunasin exhibits significant cancer-preventive, antioxidant, and hypocholesterolemic effects. This study aimed to identify quantitative trait nucleotides (QTNs) associated with lunasin content and to annotate the candidate genes in the soybean genome. The mapping panel of 144 accessions was gathered from the USDA Soybean Germplasm Collection, encompassing diverse geographical origins and genetic backgrounds, and was genotyped using SoySNP50K iSelect Beadchips. The lunasin content in soybean seeds was measured using the enzyme-linked immunosorbent assay (ELISA) method, with lipid-adjusted soybean flour prepared from seeds obtained from the Germplasm Resource Information Network (GRIN) of USDA-ARS in 2003 and …

Boston Scientific Strategic Audit, John Trilling, Carly Gorter, Anna Coffey, Leo Ray

Honors Program: Senior Projects (Public)

Boston Scientific had a strong 2023, achieving 13.6% organic growth, $1.208 billion in profit, and maintaining a focus on employee satisfaction and sustainability. Recognized as a top workplace and leading innovator, the company is well-positioned for continued success. Its competitive edge stems from four key strengths. First, its top-tier innovation, driven by strong R&D investment, reinforces its credibility and specialization. Second, its skilled workforce accelerates product development. Third, its deep product lines foster extensive industry knowledge and creativity. Lastly, its logistical capabilities and strategic acquisitions have built a specialized, dominant portfolio. With a focused differentiation strategy, Boston Scientific competes with …

The Impact Of Diabetes Education & Post Discharge Interventions For African American Adults At Risk For & After Myocardial Infarction, Trinity L. Billingsley

Nursing | Student Research Posters

Cardiovascular disease or CVD refers to a multitude of conditions that affect both the heart and blood vessels. Being the leading cause of death in the United States, heart disease claims 919,032 lives; the risk of death becomes more likely when accompanied with comorbidities like diabetes (CDC, 2024). While heart disease is a leading cause of death across all populations, it accounts for a larger proportion of deaths in African American, or AA, adults at 22.6% compared to White adults at 18.0% and Hispanic adults at 11.9%, highlighting persistent racial disparities in cardiovascular outcomes (CDC, 2024). Diabetes as a comorbidity …

Comparing Human Milk-Derived Vs Bovine-Derived Fortifiers In Formula-Fed Preterm Infants On The Incidence Of Necrotizing Enterocolitis, Maya C. Kern

Nursing | Student Research Posters

Necrotizing enterocolitis (NEC) is one of the leading causes of death in infants < 32 weeks gestation and/or < 1500g. Human breast milk lowers NEC rates through immunologic, microbial, and gut-protective mechanisms. When maternal or donor milk is unavailable, infants require formula with fortification but the safest type of fortifiers remains unclear. Bovine-derived fortifiers may increase gut inflammation; human milk-derived fortifiers may offer more protection. Limited research exists comparing these fortifiers when infants are exclusively formula fed. Determining if human milk-derived fortifiers still reduce NEC risk could influence NICU feeding guidelines and improve outcomes.

Nicorandil Treatment Improves Survival And Spatial Learning In Aged Granulin Knockout Mice, Dana M. Niedowicz, Wang-Xia Wang, Paresh Prajapati, Yu Zhong, Shuling X. Fister, Colin B. Rogers, Pradoldej Sompol, David K. Powell, Indumati Patel, Christopher M. Norris, Kathryn E. Saatman, Peter T. Nelson

Sanders-Brown Center on Aging Faculty Publications

Mutations in the human granulin (GRN) gene are associated with multiple diseases, including dementia disorders such as frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE). We studied a Grn knockout (Grn-KO) mouse model in order to evaluate a potential therapeutic strategy for these diseases using nicorandil, a commercially available agonist for the ABCC9/Abcc9-encoded regulatory subunit of the “K⁺ATP” channel that is well-tolerated in humans. Aged (13 months) Grn-KO and wild-type (WT) mice were treated as controls or with nicorandil (15 mg/kg/day) in drinking water for 7 months, then tested for neurobehavioral …

Disrupted Calcium Dynamics In Reactive Astrocytes Occur With End Feet–Arteriole Decoupling In An Amyloid Mouse Model Of Alzheimer’S Disease, Blaine Weiss, John C. Gant, Ruei-Lung Lin, Jenna L. Gollihue, Colin B. Rogers, Susan D. Kraner, Edmund B. Rucker, Yuriko Katsumata, Yang Jiang, Peter T. Nelson, Donna M. Wilcock, Pradoldej Sompol, Olivier Thibault, Christopher M. Norris

Sanders-Brown Center on Aging Faculty Publications

While cerebrovascular dysfunction and reactive astrocytosis are extensively characterized hallmarks of Alzheimer's disease (AD) and related dementias, the dynamic relationship between reactive astrocytes and cerebral vessels remains poorly understood. Here, we used jGCaMP8f and two-photon microscopy to investigate calcium signaling in multiple astrocyte subcompartments, concurrent with changes in cerebral arteriole activity, in fully awake 7- to 8-month-old male and female 5xFAD mice, a model for AD-like pathology, and wild-type (WT) littermates. In the absence of movement, spontaneous calcium transients in barrel cortex occurred more frequently in astrocyte somata, processes, and perivascular regions of 5xFAD mice. However, evoked arteriole dilations (in …

Nipping It In The Bud: The Promise And Perils Of Tort Litigation In Addressing The Health Harms Of High-Thc Products, Rebekah Ninan

Minnesota Law Review Headnotes, Vols. 107 onward (2022-present)

In the last decade use of marijuana has skyrocketed. With the legalization of marijuana in states across the country, a nascent but increasingly powerful cannabis industry has formed. This industry has not only introduced cannabis products into the mainstream, but it has created high-THC products more powerful than anything found in nature or previous black markets. These products, including oils, vapes, and edibles, may have health effects that are unlike any risks that researchers have previously identified with cannabis. Science has started to sound the alarm, but the issue has remained unaddressed in the law. Only two states have introduced …

The Solar Maya: Resilience And Strength In The Face Of Climate Change, Anna Frances Paradise

Pitzer Senior Theses

The solar maya of Yucatán, Mexico is an example of a sustainable agroecosystem that holds the potential to embed resilience in the livelihoods of those who utilize it. However, this traditional and indigenous system of agriculture is threatened by the immense forces of urbanization and modernization imposed on the area. I conducted research that included 14 different in-person and online interviews of academic and local personnel in Mérida and in nearby Yucatecan municipalities as well as visited seven different solares mayas, documenting my findings through audio recordings and photographs. With this collection of qualitative data, I found trends in the …

The Impacts Of Dietary And Educational Intervention In Addressing Adult Obesity In The Mexican Population, Matthew C. Servin

CMC Senior Theses

Mexico’s obesity epidemic has been an ongoing issue for the past few decades, with multiple studies attributing this to the disparities in accessing healthy food and health education. Designing a solution to Mexico’s adult obesity crisis will focus on studying the effects of an intervention plan that addresses these obesogenic factors. This proposed study will assess how a token system and health education sessions may impact the risk of obesity in the adult Mexican population. This study also will consider any limitations that arise when only one of the two intervention methods are used. As these interventions are implemented over …

Controlled Experimental Design Of Neurocognitive Delay Of Alzheimer’S In Standard American, Mediterranean, And Dash Diet Research Proposal, Jasmine Kaur

High Impact Practices Student Showcase Spring 2025

Alzheimer’s disease is an incurable illness of the neuronal system of which has been studied extensively The study presented intends to evaluate the effect of the MIND and the mediterranean diet in the prevention of Alzheimer’s disease, as well as the effect of the Standard American Diet on the development of it as well. Unlike many studies involving the effects of diet in the development of the disease in older populations, this study would involve UCF college students who are scheduled to graduate in 2030. The participants would be evaluated using the Cognitive Function Battery, a series of tests shown …