Digital Commons Network^™

Mucin And Splice Variant Profiles Of Pancreatic Adenocarcinoma Predict Patient Survival And Subtyping, Christopher M. Thompson

Theses & Dissertations

PDAC is a pancreatic epithelial malignancy and demonstrates aggressive progression and bleak patient prognosis. Despite decades of research, the evolution of novel diagnostics and intervention modalities for PDAC is stagnant. This dissertation explores the characteristic aberrant and elevated expression of mucins in PDAC. Beginning with the hypothesis that mucins are associated with disease aggressiveness, analysis of PDAC patient survival in TCGA revealed no associations between single mucin expression and patient survival. This led to the underlying issue of PDAC tumor cellularity since this disease demonstrates variability in the proportion of cancer cells within the tumor. Tumor purity assessed with the …

An Explanatory Sequential Mixed Methods Nutrition And Physical Activity Intervention Study On Changes In Knowledge, Self-Efficacy, And Outcome Expectations Of Fathers, Sarah Hortman

Theses & Dissertations

Overweight and obesity rates are a continuing concern resulting in poor health outcomes and annual healthcare costs in the billions of dollars. An upstream approach of health promotion is critical to change the focus from treatment and management to prevention of chronic disease. Preventing chronic disease through evidence-based health promotion practices incorporating educational interventions aimed at dietary and physical activity behaviors will preclude negative health outcomes including cardiovascular disease, type 2 diabetes, and hypertension.

The family environment is an important consideration in the prevention of chronic disease including obesity. Parents are role models for their children, including fathers who are …

Effect Of Aerobic Exercise With Blood Flow Restriction On Substrate Utilization And Energy Expenditure, Nathen Andrews

Honors Theses

The purpose of this study was to examine the effects of intermittent blood flow restriction (BFR) compared to low- (LIIE) and high-intensity interval exercise (HIIE) on energy expenditure (EE) and substrate utilization. Participants randomly performed each interval exercise protocol, and then rested for a three-hour period, in which EE and substrate utilization were measured. Total EE was different between BFR (321.6 ± 30.1 kcals), HIIE (254.5 ± 33.5 kcals), and LIIE (287.1 ± 25.5 kcals). Fat oxidation (FatOx) in BFR (1hr = 0.14 ± 0.01 g / min, 3hr = 0.11 ± 0.01 g / min) was greater than LIIE …

Decreased Activity Of Phosphofructokinase-1 In Flight Muscle Cells Of Hawk Moth Manduca Sexta With Age, Owen G. Alvine

Honors Thesis

The phosphofructokinase-1 (PFK-1) enzyme is important for the catalyzation and regulation of glycolysis, especially in muscle. Investigating age-related changes in PFK-1 activity will provide insights into the metabolism shifts in muscle cells of our muscle aging model. The hawk moth, Manduca sexta, was chosen as the model organism because of its unique endothermic, synchronous flight muscles that are more analogous to vertebrates than invertebrate species. We hypothesized that PFK-1 activity will increase in muscle cells of aged moths due to dysregulation of the mitochondria. This was predicted to change the method of energy production, by hindering oxidative phosphorylation, making glycolysis …

Exploring Occupational Therapy With Athletes Using Principles Of Lifestyle Redesign® To Support Academic Success And Life Balance., Michaela M. Dendinger

Occupational Therapy Capstone Presentations

Occupational therapists have a range of skills that can benefit a variety of populations. Despite these skills, occupational therapy has limited exploration within the field of athletics. The capstone project gave insight to the services occupational therapy can provide to the student-athlete population. Through the lens of Lifestyle Redesign®, the Student-Athlete Wellness Program was created to support student-athlete academic success and life balance. Following a needs assessment an online program was developed. The program was provided to students and athletes a University in the Midwest U.S. The program attracted 21 student-athletes and five students. Limited participation in surveys provided difficulties …

Implementation Of A Nurse-Led Family Centered Engagement Intervention For Caregivers Of Extremely Premature Infants In The Neonatal Intensive Care Unit, Emily Keenan, Michaela L. Ranallo, Kathleen A. Walsh, Haley Chapko, Tiffany A. Moore

Doctor of Nursing Practice Projects: College of Nursing

Objective: The objective of this feasibility study was to examine the implementation and usefulness of an intervention for extremely premature infant (EPI) caregivers.

Results: One caregiver and five nurses provided feedback with a mean score of 4.4 out of 5 pertaining to helpfulness.

Conclusions: Implementation of the Caregiver’s Guide was feasible and was positively received by NICU nurses and caregivers. We recommend implementing a revised version of this tool based on nurse and caregiver feedback. The delivery of education should be divided between dayshift and nightshift nurses so that one nurse is not responsible for providing all the information. The …

Introduction Of Strong For Surgery Pre-Surgical Checklist For Elective Procedures​, Dylan Defauw

Doctor of Nursing Practice Projects

Nearly one-third of hospitalized patients experience preventable harm or adverse effects related to the care they received, often due to preventable surgical complications. Thorough preoperative assessment and management of risk factors can lessen this risk. The purpose of this quality improvement project was to increase knowledge and prepare staff for use of the preoperative tool Strong for Surgery (S4S) in a general surgery clinic in a rural hospital in southern Illinois. Support for each of the key components of the Strong for Surgery pre-surgical checklist was reviewed in the literature; these include nutrition, smoking cessation, glycemic control, medication management, safe …

Culturally Appropriate Health Education: Translation Of A Parturient Pain Relief Options Pamphlet Into French And Spanish, Francis Minor, Austin Cook

Doctor of Nursing Practice Projects

The rise of immigration worldwide introduces a diverse, multicultural population of patients seeking healthcare in the United States. Barriers to communication, both spoken language and culturally associated communication norms, limit immigrant women’s ability to seek, gain access, and follow through with perinatal care. In order to provide safe, effective, and culturally sensitive care, recognition of language and cultural differences of all individuals must be considered when providing patients with educational materials (Perera et al., 2012; Plumbaum et al., 2014). The aim of this project was to translate an existing pain relief options pamphlet into French and Spanish in order to …

2021 Spring Commencement, Harding University

Commencement Programs

Program for the Harding University Commencements on May 7th and 8th.

Commencement Speakers:
May 7th: Dale Manor
May 8th 9a.m.: Ann Brown
May 8th noon: John Henderson
May 8th 3p.m.: Clifton L. Ganus III
May 8th 6p.m.: John K. Cameron

Scientometric Analysis Of Spice Research Publications In India From Scopus Database During 2010- 2019, Vivekanandhan S, Govindasamy M Mr, Sivasamy K Dr

Library Philosophy and Practice (e-journal)

This paper presents the scientometric analysis of Spice research publications in India from SCOPUS database during 2010 - 2019 with 3120 research publications. During the Study period, maximum of 400(12.82%) research publications are contributed in the year 2018 and 2019, average research publication per year is 312 and CAGR is 8.62. Relative growth rate is 0.92 in the year 2011 and 0.14 in the year 2019, at the same time doubling time is 0.75 in the year 2011 and 5.05 in the year 2019. Out of 3120 research publications, 179(5.74%) publications are contributed by single author’s publications and remaining 2941(94.26%) …

Variation In Forage Quality Of Three Rangeland Species In Different Phenological Stages, S. A. Javadi, H. Arzani

IGC Proceedings (1977-2023)

No abstract provided.

Influence Of Germination On The Soluble Carbohydrates In Feed Legumes, María Felicia Díaz, María A. Martín‐Cabrejas, Yolanda Aguilera, Vanesa Benítez, Esperanza Mollá, Rosa M. Esteban

IGC Proceedings (1977-2023)

No abstract provided.

How Do Food And Physical Activity Policies Affect Our Health?, Chris Long

Diet, Food, Exercise, and Nutrition (D-FEND)

Policy is generally defined and then tied into how food and physical health policies affect our everyday lives.

Spring Commencement Program, May 7-8, 2021, Coastal Carolina University

Commencement Programs

Program of Commencement Exercises at Coastal Carolina University.

Southern Adventist University Commencement Program May 7 And May 9, Southern Adventist University

Commencement Programs

Program for Southern Adventist University May graduation. The commencement service took place at the Iles Physical Education Center on May 7 and May 9, 2021.

Commencement [Program], May 7-8, 2021, University Of Northern Iowa

UNI Commencement Programs

The program of the commencement ceremonies, including a list of institutional leadership, a list of the departments by college, awards given at the ceremonies, and a list of undergraduate and graduate degree candidates.

The Effects Of Diabetes Education On Long-Term Complications, Sunny Lawrence

Doctor of Nursing Practice Scholarly Project

The purpose of the scholarly project is to: a) Evaluate if diabetes education can improve a patient’s overall condition; b) Measure the chances of reducing long-term complications if a person is to participate in diabetes education and continue to follow up; c) Demonstrate that with effective diabetes self-management education (DSME) hemoglobin A1c can be reduced. The project design and target population were selected based on research performed on diabetes and diabetes education and the effects that it has on improving self-management in turn creating better glycemic control and fewer complications. This study will focus on type 2 diabetes, which is …

Learn Grow Eat, Laura Dolezal, Arianne Kozeluh, Rachel Mannen

Health Fair: Tools & Lessons for K-12

No abstract provided.

Utah State University Commencement, 2021 – College Of Agriculture And Applied Sciences Convocation, Utah State University

Commencement Programs

2021 Convocation for the College of Agriculture and Applied Sciences of Utah State University.

Education For Healthcare Providers, Nurses, And The Public On Opioid Induced Hyperalgesia, Jenny Greene

Doctor of Nursing Practice Scholarly Project

This project evaluated the knowledge of the public, healthcare providers, and nurses regarding opioid induced hyperalgesia (OIH). OIH is an elevated pain response because of high dosage or chronic use of opioids. Opioids are a problem not only in the United States but throughout the world; addiction, constipation, and overdose are the most frequently mentioned consequences of opioids. Little is known about other consequences to the body caused by chronic or high dose opioid usage, such as OIH. This project sought to increase awareness and caution against the utilization of opioids by patients and their healthcare providers and nurses practice. …

Effects Of Oxidative Stress On The Astaxanthin Biosynthesis Pathway Of Haematococcus Pluvialis, Rachel Cray

All Student Scholarship

Astaxanthin is a key carotenoid pigment produced primarily in nature by the unicellular microalga Haematococcus pluvialis. This potent antioxidant is produced in response to environmental stressors, such as high light, upon which reactive oxygen species (ROS) are produced. While the presence of ROS has been established in this cascade via carotenogenic genes, its effect has not been defined. The overall goal of this study was to quantify the effect of ROS on the astaxanthin biosynthesis pathway within H. pluvialis. Cellular ROS concentrations and astaxanthin output were quantified in response to environmental variables, redox-sensitive compounds, and ROS-scavengers. All environmental and redox-sensitive …

Evaluation Of Chili Pepper (Capsicum Annuum), Tiger Nuts (Cyperus Esculentus), And Turmeric (Curcuma Longa) As Sources Of Antioxidant Compounds For The Potential Of Antiaging-Like Activity, Chelsea Toyer

Theses

Aging is a natural process that living organisms go through as they become older. In humans and other animals, aging is accompanied by several morphological changes, including the formation of wrinkles. Wrinkles are also caused by various environmental factors such as excessive exposure to sun or pollution, and continuous sleep deprivation. These environmental factors cause oxidation of skin cells and the degradation of subcutaneous fatty acids, leading to the formation of wrinkles. Skin care and wrinkle treatment products are part of a multimillion-dollar industry. Plant-based products are an alternative method for treating wrinkles and premature aging. Several antioxidants naturally found …

Black Holistic: A Response To Respiratory Health And Equity Through K-12 Environments And Community - Based Design, Azha Parker

Bachelor of Architecture Theses - 5th Year

The overarching aim of this thesis is to investigate the causes of higher amounts of absenteeism due to asthmatic disease within African American students as it pertains to building-related illness and environmental harms. With this information, design decisions will be made to respond to asthma symptoms amongst students and introduce new outlooks towards health within the communities non-intrusively. Looking at Lakeview Elementary School in Portsmouth, Virginia as a case. This majority African American school sits adjacent to a preexisting landfill that has been capped before construction of the school. This site will act as an example, showing the relationships between …

[Re]Discovering Nature | Ecotourism & Natural Resource Conservation: The ‘Potential’ For A Sustainable Symbiotic Relationship, Amber Bennett

Bachelor of Architecture Theses - 5th Year

Humans are more disconnected than ever from the natural environment. Architecture and ecology, both providing distinct conceptual frameworks for the city, one for nature and one for culture, these thesis explores the frameworks that call for them to be intersected to further an actionable ecology for the city and its architecture. Interaction with the natural environment is crucial to human well-being and development, but sadly this connection has diminished drastically due to the over-reliance on modern-day advances and technology. This severed relationship attributes to the lack of awareness of pressing environmental issues that are threatening our shared communities. Islands, remote …

Rethinking The Needs Of The Invisible Society Through Empowerment, Jada Ross

Bachelor of Architecture Theses - 5th Year

This thesis addresses the issue of homelessness and is intended to spark an open conversation about how we can redefine our perceptions of families who experience homelessness. The proposal aims to explore and establish an transitional intervention for “invisible” families to live and develop into contributing residents of society. In the United States, the most vulnerable population are families with children, accounting for 33% of the homeless population. As Covid19 cases continue to rise, and policies continue to neglect affordable housing options, the number of families experiencing homelessness will continue to grow in the future. Through the analysis of case …

Revival Of The Dead Zone- Ecotourism Within The Chornobyl Exclusion Zone, Angelina Damaj

Bachelor of Architecture Theses - 5th Year

Since the nuclear accident, Chernobyl has been abandoned for 30 years. 30 kilometers around Chernobyl was evacuated and it has left the area to become a dead zone. In actuality the dead zone is full of life. Plant and animal populations have expanded and thrived, and people have slowly started to reenter the zone. The exclusion zone has become a new ecosystem.

With more people coming into Chernobyl for tourism, there is higher risk of the ecosystem being threatened. My thesis will explore ecotourism within the Chernobyl exclusion zone. My proposal is an urban design that is shaped by ecotourist …

A Quality Improvement Initiative To Decrease Fall Risk In Community Dwelling Elderly, Michele Shearer

Doctor of Nursing Practice (DNP) Manuscripts

Falls are a health concern for the elderly and are the leading cause of fatal and non-fatal fall injuries in this population (Burns & Lee, 2016). Meijers, et al. (2012) found that one in three community dwelling elderly will experience at least one fall per year with an even higher rate in adults greater than 80 years old. Numbers of falls are expected to increase as this population ages. This increase in falls and their consequences will produce an enormous economic burden on the United States health care system (Burns & Lee, 2016). The purpose of this program was to …

Explaining Reproductive Health Disparities: Violence In The “Colorblind” Institution Of Medicine, Chineze Osakwe

Honors Scholar Theses

Medical policies have resulted in violence that has a formal role in regulating the reproductive rights of women of African descent in the United States from the Jim Crow era (circa 1965) to present day (2021), resulting in significantly racialized reproductive health disparities regardless of social or economic influences. This thesis explores why reproductive violence against African-American women persists, regardless of women’s own class and educational background. I have focused on the potential impact of two structural components that I hypothesized contributed to the perpetuation of reproductive violence against Black women and persistent health disparities. The two factors explored in …

Empowering Mothers: A Conceptual Model For Promoting Perinatal Mental Wellness Among Women In The United States, Kayla Acklin

Electronic Theses and Dissertations

Globally, there are certain expectations surrounding becoming a mother related to pregnancy and the birth. For many women, the birth of a child represents a natural event filled with joy. Societally, the expectation is that pregnancy, birth, and the transition into motherhood are normal, positive experiences for all women (Davis-Floyd & Cheyney, 2019). However, research shows that some women develop impairments in physical and mental health functioning and wellbeing as a result of the major physical and psychosocial changes that take place during the transition into motherhood (Austin et al., 2010; Ayers & Pickering, 2001; O’Hara et al., 2014).

This …

Professional Ethics For College Health Services, Dessa Mrvos

Electronic Theses and Dissertations

College health services provide a crucial resource for campus communities in the United States, substantially affecting student health, safety, and wellbeing. The impact and quality of campus clinical services impact student life through varied approaches to the delivery of services, health innovations, and business models. The role that campus health services plays in dealing with risk mitigation is essential: well-established public health principles of disease prevention, health promotion, and health education are sustained and advanced by campus clinical health services. Despite the widely recognized importance of college health services, there is very little literature on the contribution of ethics related …