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Convective-Diffusive Transport In Krogh Cylinders: A Model For Pharmacokinetics, Xianjie Qiu

Doctoral Dissertations

"Drug delivery to inside of the tumor is the important problem. The dynamics of drug delivery is presented here. Previously and particularly for directed delivery, a stirred tank model has been used, which appears to have worked well when compared to experiments. However, the stirred tank models do not include all the mass transfer resistances and towards that end we have used a distributed system called Krogh cylinder. This study focuses on the Krogh cylinder model simulation, both on the fluid flow and the mass transfer. The capillary network is broken down into cylindrical cells, each containing a capillary and …