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The Oswald Review Undergraduate Research And Criticism In The Discipline Of English: Volume 14 Fall 2012

The Oswald Review: An International Journal of Undergraduate Research and Criticism in the Discipline of English

No abstract provided.

Appraisal Investigation Alternative Water Supply For Langdon Rural Water District, Geoffrey Brian Slick

Theses and Dissertations

No abstract provided.

Walking The Tight Rope And Not The Plank: A Proposed Standard For Second-Level Appellate Review Of Equitable Mootness Determinations, Matthew D. Pechous

Emory Bankruptcy Developments Journal

The Comment proposes that, for doctrinal and practical reasons, determinations of equitable mootness should be reviewed for an abuse of discretion. However, numerous scholars have recognized that the deference granted under the abuse of discretion standard is more of a spectrum than a single, easily definable standard. Therefore, the Comment also suggests that courts of appeals should be more willing to overturn determinations of equitable mootness than other issues reviewed for an abuse of discretion.

Bankruptcy Stigma And Vulnerability: Questioning Autonomy And Structuring Resilience, Yvana L.B.H. Mols

Emory Bankruptcy Developments Journal

Stigma is an enduring byproduct of bankruptcy, both as felt by the debtor and as perceived by society. The stigma exists even though some have declared its demise, and is certainly present after the BAPCPA amendments aimed at action intended to revive the stigmatic effect of filing for bankruptcy. Bankruptcy stigma may be a useful tool when it prompts individuals to make wiser fiscal decisions, but for debtors who face uncontrollable financial circumstances, this same stigma is burdensome and does not provide a social benefit.

Does Mucosal Or Serosal Side Approximation Affect The Efficacy Of Native Small Intestinal Submucosa Graft Repair Of Neurotmesis?, Ferro Nguyen

PCOM Biomedical Studies Student Scholarship

FDA approved, commercial, modified porcine small intestinal submucosa (SIS) is utilized clinically for peripheral nerve repair. However, if measures can be put in place to insure its safety, native SIS prepared from locally available porcine resources would provide easy access to an inexpensive alternative. Both forms of this material lack antigenicity, have inherit properties which provides a favorable growth environment, and have been successfully used experimentally as a natural conduit in peripheral nerve repair. Successful recovery from a peripheral nerve injury is dependent on the efficiency and speed of axonal regeneration to the point of distal interruption of the nerve. …

Role Of Na+K+2cl- Co-Transporters In Insulin Secretion, Saeed Alshahrani

Browse all Theses and Dissertations

The objective of this study is to investigate the role of intracellular chloride concentration ([Cl^-]i) in insulin secretion in vivo and in vitro.

The maintenance of high [Cl^-]i in insulin-secreting pancreatic β-cells plays an important role in glucose-induced depolarization and insulin secretion. Insulinotropic glucose concentrations i.e., >6 mM induces electrical activity in β-cells which results in insulin secretion. This electrical activity is mainly due to electrogenic efflux of Cl^- from β-cells through volume-regulated anion channels (VRAC). The solute carrier family 12 group A member 1 (Slc12a1) and 2 (Slc12a2) encode several splice variants of the …

Computational Investigation Of A Hinge-Connected Hovering Plate, Zachary Robert Gaston

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A simplified conceptual flapping wing MAV design, capable of hover, is formed from the works of both biologists and engineers, studying the behavior of flying insects and the aerodynamics of flapping flight. With this new model, hovering hinged plates are used to study the effects of passive deflection on aerodynamic performance using two-dimensional Direct Numerical Simulations (DNS) at low Reynolds numbers (Re). The hinge is modeled as a torsional spring at the leading edge, where prescribed motion is applied. The influence of forced-to-natural frequency ratio (hinge stiffness) and stroke-to-chord ratio (leading edge kinematics) are studied, to explore the effects that …

Micro-Raman Imaging And Hyperspectral Analysis Of Tibiotarsi From Chick Embryos Exposed To Sublethal Doses Of Platinum Group Metals, Adam Christopher Stahler

Browse all Theses and Dissertations

Platinum group metals (PGMs), i.e., Pd, Pt and Rh, are found at pollutant levels in the environment. PGMs accumulate in plant and animal tissues, and little is known about their toxicity. Our previous studies have shown that chick embryos exposed to 1.0 mL PGM solutions of 5.0 ppm (LD₅₀) and higher exhibited severe skeletal deformities. This work hypothesized that 1.0 ppm sublethal doses of PGMs would negatively impact the mineralization process in tibiotarsi. One milliliter of 1.0 ppm of Pd(II), Pt(IV), Rh(III) aqueous salt solutions and a PGM-mixture were injected into the air sac of the eggs …

Human Action Recognition By Principal Component Analysis Of Motion Curves, Daniel Stephen Chivers

Browse all Theses and Dissertations

Human action recognition is used to automatically detect and recognize actions per- formed by humans in a video. Applications include visual surveillance, human-computer interaction, and robot intelligence, to name a few. An example of a surveillance application is a system that monitors a large public area, such as an airport, for suspicious activity. In human-machine interaction, computers may be controlled by simple human actions. For example, the motion of an arm may instruct the computer to rotate a 3-D model that is being displayed. Human action recognition is also an important capability of intelligent robots that interact with humans.

General …

Effects Of Cross-Fostering On Alcohol Preference And Correlated Responses To Selection In High- And Low-Alcohol Preferring Mice, G. D. Barrenha, Julia Chester

Department of Psychological Sciences Faculty Publications

Background: Selectively bred rodent lines are valuable tools for investigating gene x environment interactions related to risk for alcoholism in humans. Early maternal environment is one particular factor known for critically influencing neural, hormonal, and behavioral outcomes in adulthood. Cross-fostering is a procedure that may be used to explore the role of genotype-dependent maternal influences on phenotypic variability in adulthood. The purpose of these experiments was to examine the effects of cross-fostering on free-choice alcohol drinking and correlated responses to selection for alcohol preference in mice selectively bred for high- (HAP2) and low- (LAP2) alcohol preference. Methods: Mice were assigned …

Emergent Identity Matching After Successive Matching Training Ii: Reflexivity Or Transitivity?, Peter J. Urcuioli, Melissa Swisher

Department of Psychological Sciences Faculty Publications

Three experiments evaluated whether the apparent reflexivity effect reported by Sweeney and Urcuioli (2010) for pigeons might, in fact, be transitivity. In Experiment 1, pigeons learned symmetrically reinforced hue-form (A-B) and form-hue (B-A) successive matching. Those also trained on form-form (B-B) matching responded more to hue comparisons that matched their preceding samples on subsequent hue-hue (A-A) probe trials. By contrast, most pigeons trained on just A-B and B-A matching did not show this effect; but some did – a finding consistent with transitivity. Experiment 2 showed that the latter pigeons also responded more to form comparisons that matched their preceding …

Early Postnatal Overnutrition: Potential Roles Of Gastrointestinal Vagal Afferents And Brain-Derived Neurotrophic Factor, Edward A. Fox, Jessica E. Biddinger

Department of Psychological Sciences Faculty Publications

Early postnatal overnutrition: Potential roles of gastrointestinal vagal afferents and brain-derived neurotrophic factor. PHYSIOL BEHAV 00(0) 000-000, 2012. Abnormal perinatal nutrition (APN) results in a predisposition to develop obesity and the metabolic syndrome and thus may contribute to the prevalence of these disorders. Obesity, including that which develops in organisms exposed to APN, has been associated with increased meal size. Vagal afferents of the gastrointestinal (GI) tract contribute to regulation of meal size by transmitting satiation signals from gut-to-brain. Consequently, APN could increase meal size by altering this signaling, possibly through changes in expression of factors that control vagal afferent …

Treating Diet - Induced Obesity: A New Role For Vagal Afferents?, Edward A. Fox

Department of Psychological Sciences Faculty Publications

No abstract provided.

Design And Synthesis Of Hiv-1 Integrase Inhibitors, Sarah Chajkowski Scarry

Electronic Theses and Dissertations

In recent years, HIV-1 integrase (IN) has emerged as an attractive target for the treatment of human immunodeficiency virus type 1 (HIV-1), the causative pathogen of acquired immuno-deficiency syndrome (AIDS). Several classes of IN inhibitors are known but many of these compounds are toxic, do not show antiviral activity or display decreased potency. Therefore, new classes of potent IN inhibitors are desperately needed. The b-diketo (b-DK) class of compounds has emerged as one of the most successful classes of IN inhibitors. Although several b-DK inhibitors with potent antiviral activity are known, compounds containing b-DK motifs have limitations in drug development. …

How Do The Perceived Barriers, Attitudes, And Knowledge Of Grocery Store Personnel Affect Availability Of Organic Food Products?, Rachel Adams

Electronic Theses and Dissertations

Organic food is one of the fastest-growing segments of food production and consumption in the U.S. Even though organic foods are becoming more widely available, some studies suggest they may not be equally available to all populations because people in some areas are being excluded from the organics market either geographically or financially. The purpose of this study was to examine how individual and local characteristics affect the attitudes of grocery store personnel toward organic food products and how these attitudes affect availability. Grocery store personnel were surveyed about their attitudes toward organic foods, their perceptions of the barriers to …

Given: F(A Great Love + A Missing Body), Emily Anne Barnes

Electronic Theses and Dissertations

Given: f(A great love + A missing body) is a collection of poems in four sections that takes love and mathematics at its core. The lyric and narrative poems navigate an affair between a female narrator and her lover. The math is positioned with the verse in the way an ekphrastic poem might be positioned next to the art upon which it is based. The connection and alienation of the form fractures the poem, but it also serves as a metaphor for the competing forces of two people in love. And the goal of each is pursuit of the sublime. …

Predicting Success Or Failure Of Immunotherapy For Cancer: Insights From A Clinically Applicable Mathematical Model, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

The objective of this study was to create a clinically applicable mathematical model of immunotherapy for cancer and use it to explore differences between successful and unsuccessful treatment scenarios. The simplified predator-prey model includes four lumped parameters: tumor growth rate, g; immune cell killing efficiency, k; immune cell signaling factor, λ; and immune cell half-life decay, μ. The predator-prey equations as functions of time, t, for normalized tumor cell numbers, y, (the prey) and immunocyte numbers, x, (the predators) are: dy/dt = gy – kx and dx/dt = λxy – μx. A parameter estimation procedure that capitalizes on available clinical …

Optimizing Electrode Placement For Hemodynamic Benefit In Cardiac Resynchronization Therapy, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Background: Research is needed to explore the relative benefits of alternative electrode placements in biventricular and left ventricular pacing for heart failure with left bundle branch block (LBBB). Methods: A fast computational model of the left ventricle, running on an ordinary laptop computer, was created to simulate the spread of electrical activation over the myocardial surface, together with the resulting electrocardiogram, segmental wall motion, stroke volume, and ejection fraction in the presence of varying degrees of mitral regurgitation. Arbitrary zones of scar and blocked electrical conduction could be modeled. Results: Simulations showed there are both sweet spots and poor spots …

Climatic Effects Of The Chicxulub Impact Ejecta, Devon Parkos, Marat Kulakhmetov, Brandon Johnson, Henry J. Melosh, Alina A. Alexeenko

School of Aeronautics and Astronautics Faculty Publications

Examining the short and long term effects of the Chicxulub impact is critical for understanding how life developed on Earth. While the aftermath of the initial impact would have produced harmful levels of radiation sufficient for eradicating a large portion of terrestrial life, this process does not explain the concurrent marine extinction. Following the primary impact, a large quantity of smaller spherules would de-orbit and re-enter the earths atmosphere, dispersed nearly uniformly across the planet. This secondary wave of debris would re-enter at high velocities, altering the chemical composition of the atmosphere. Furthermore, the combined surface area for the spherules …

Using Surface Tension Gradients To Reduce Condensate Retention And Improve Heat Exchanger Performance In Air Conditioning Systems, Tyler J. Brest, Khalid F. Eid, Andrew D. Sommers

International Refrigeration and Air Conditioning Conference

This paper presents a novel method for patterning metal fin surfaces used in HVAC&R applications to mitigate problems associated with condensate retention. In this work, metallic surfaces are patterned to promote water droplet migration towards a specified region acting as a central drainage conduit. The surfaces were fabricated using photolithography, physical vapor deposition, and a surface-specific chemical coating and then characterized using spray (fine mist) testing and small droplet (2-10 μL) injection via microsyringe. In this study, we have also analyzed the effect of the chemical treatment on the observed wettability change (i.e. the degree of transformation of our surfaces …

Biology And Nursing Students’ Perceptions Of A Web-Based Information Literacy Tutorial, Sharon A. Weiner, Nancy Pelaez, Karen Chang, John M. Weiner

Libraries Faculty and Staff Scholarship and Research

This study examined the perceptions of two groups of students to obtain different perspectives on the online information literacy tutorial, CORE (Comprehensive Online Research Education, to plan for its update. The CORE tutorial includes seven modules: “Planning Your Project,” “Topic Exploration,” “Types of Information,” “Search Tools,” “Search Strategies,” “Evaluating Sources,” and “Copyright, Plagiarism, and Citing Sources.” First-year students in biology and nursing courses responded to a survey after completing the CORE modules. Students indicated that they liked learning through an online tutorial. However, they thought that the tutorial could be improved with shorter modules and the addition of video and …

Co-Designing, Co-Developing, And Co-Implementing An Institutional Data Repository Service, Michael Witt

Libraries Faculty and Staff Scholarship and Research

In January of 2011, the National Science Foundation began requiring that all proposals for research funding include data management plans. At the time of the mandate, Purdue University's library and campus information technology units had been collaborating on enhancements to the HUBzero virtual research environment. These efforts were parlayed into the development of an institutional, digital data repository and service with the support of the campus research office. In the process, local library science practices have been extended to facilitate research data curation and cyberinfrastructure on campus. Librarians are consulting on data management plans, conducting data reference and instruction, advising …

A Replication And Extension Of The Anti-Symmetry Effect In Pigeons, Peter J. Urcuioli, Melissa Swisher

Department of Psychological Sciences Faculty Publications

Pigeons trained on successive AB symbolic matching show emergent BA anti-symmetry if they are also trained on successive AA oddity and BB identity (Urcuioli, 2008, Experiment 4). In other words, when tested on BA probe trials following training, they respond more to the comparisons on the reverse of the non-reinforced AB baseline trials than on the reverse of the reinforced AB baseline trials (the opposite of an associative symmetry pattern). The present experiment replicated this finding. In addition, it showed that anti-symmetry also emerged after baseline training on successive AB symbolic matching, AA identity, and BB oddity, consistent with the …

Placing Birds On A Dynamic Evolutionary Map: Using Digital Tools To Update The Evolutionary Metaphor Of The "Tree Of Life", Sonia Stephens

Electronic Theses and Dissertations

This dissertation describes and presents a new type of interactive visualization for communicating about evolutionary biology, the dynamic evolutionary map. This web-based tool utilizes a novel map-based metaphor to visualize evolution, rather than the traditional "tree of life." The dissertation begins with an analysis of the conceptual affordances of the traditional tree of life as the dominant metaphor for evolution. Next, theories from digital media, visualization, and cognitive science research are synthesized to support the assertion that digital media tools can extend the types of visual metaphors we use in science communication in order to overcome conceptual limitations of traditional …

The Role Of Flow In Creating E-Loyalty: The Case Of Online Hotel Booking Websites, Anil Bilgihan

Electronic Theses and Dissertations

This dissertation aims to examine the concept of ―online customer experience‖, ―flow‖, and its role in influencing online customers‘ loyalty to a hotel booking website. To achieve this aim, a model was developed, which proposed that online flow is generated by both hedonic and utilitarian website features. A model was developed based on literature review to measure the relationships between the constructs. To initiate this research, a survey approach was taken. After conducting a pilot study, a marketing company was contacted to distribute the link for the online questionnaire. Five hundred and eleven (511) questionnaires were completed by guests who …

Use Of Methionine Sulfoximine To Dissect The Role Of Glutamine Synthetase And Glutamine In Progression Of Acute Liver Failure, Amruta Anil Jambekar

Wayne State University Dissertations

Methionine sulfoximine (MSO) is a modified amino acid and a well characterized irreversible inhibitor of glutamine synthetase (GS) enzyme. Glutamine is synthesized by GS enzyme and it is the most abundant amino acid in the body. Glutamine is required by immune cells for generation, propagation and maintenance of an immune response.

To induce acute liver failure (ALF) in mice, animals were given intraperitoneal injections of E. coli lipopolysaccharides (LPS) and sugar D-galactosamine (D-GalN). When these animals were pretreated with MSO, 80% of the animals were completely rescued from liver failure. Moreover, when we characterized the immune response generated during ALF …

Phylogenetic Utility Of Mitochondrial And Nuclear Genes: A Case Study In The Diptera (True Flies), Jason Caravas

Wayne State University Dissertations

The value of mitochondrial versus nuclear gene sequence data in phylogenetic analysis has received much attention without yielding definitive conclusions. Theoretical arguments and empirical data suggest a lower phylogenetic utility than equivalent nuclear gene sequences, but there are also many examples of important progress made using mitochondrial sequences. We therefore undertook a systematic performance analysis of mitochondrial and nuclear sequence partitions taken from a representative sample of dipteran species. For phylogenetic tree reconstruction, mitochondrial genes performed generally inferior to nuclear genes. However, the mitochondrial genes resolved branches for which nuclear genes failed. Moreover, the combined use of mitochondrial and nuclear …

A Higher Education Case: Millennial Experience Toward Learning Through A Virtual World Designed As An Authentic Learning Environment, Marija Franetovic

Wayne State University Dissertations

Current educational initiatives encourage the use of authentic learning environments to realistically prepare students for jobs in a constantly changing world. Many students of the Millennial generation may be social media savvy. However, what can be said about learning conditions and student readiness for active, reflective and collaborative learning and media literacy within their discipline? Virtual worlds such as Second Life (SL) represent future hybridized work environments which can support authentic learning. With their immersive and interaction affordances, virtual worlds may be designed to incorporate real-world team projects for both online and blended courses.

This qualitative single embedded case study …

Sex Differences In The Cardiac Beta-Adrenergic Receptor Contractile Response, Victoria Mcintosh

Wayne State University Dissertations

Premenopausal females are at a reduced risk for developing cardiovascular disease as compared to males; this sex difference is not present following menopause. &beta-adrenergic receptors are pharmaceutical targets in the treatment of cardiovascular disease, and sex differences in &beta-adrenergic responsiveness have been demonstrated. However, limited studies have addressed the mechanism(s) underlying these differences. To investigate these sex differences, studies were performed using isolated perfused hearts from male, intact female and ovariectomized female mice, as well as male and female ventricular myocytes. Female hearts exhibited blunted contractile responses to the &beta-adrenergic receptor agonist isoproterenol (ISO) compared to males but not ovariectomized …

Hallowed Ground: Literature And The Encounter With God In Post-Reformtion England, C. 1550 - 1704, Michael Thomas Martin

Wayne State University Dissertations

This dissertation examines the ways in which the encounter with God is figured in post-Reformation English writing between the years 1550 and 1704. The introduction contextualizes the ways in which individuals might encounter God within cultural and historical circumstances of the period: the gradual disappearance of the tradition of spiritual direction that accompanied the suppression of Catholicism in England during the period and the growing influence of more purely "scientific" modes of inquiry, especially after Descartes. Because of these changes, the ways the encounter with God could be experienced were also changing. The introduction also shows how developments in religious …