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Research At Nebraska, 2002-2003 Report, University Of Nebraska-Lincoln

Office of Research and Economic Development: Publications

This publication is a snapshot of the fiscal year’s activities. To read more stories about research and creativity at Nebraska, visit the online edition at http://research.unl.edu/news/03_ORGS_(AR_2.9.03)_Final.pdf. Additional multimedia are available for many stories.

Hiv And Art: Reproductive Choices And Challenges, Nanette R. Elster

Journal of Contemporary Health Law & Policy (1985-2015)

No abstract provided.

Modernizing Local Responses To Public Health Emergencies: Bioterrorism, Epidemics, And The Model State Emergency Health Powers Act, Daniel S. Reich

Journal of Contemporary Health Law & Policy (1985-2015)

No abstract provided.

Response Of Blackberry Cultivars To Nematode Transmission Of Tobacco Ringspot Virus, Alisha Sanny

Inquiry: The University of Arkansas Undergraduate Research Journal

A study was conducted on eight cultivars of blackberry ('Apache', 'Arapaho', 'Chester', 'Chickasaw', 'Kiowa', 'Navaho', 'Shawnee', and 'Triple Crown'), of which four plants of each were previously determined in the fall of 2001 to have root, but not leaf, infection with Tobacco ringspot virus (TRSV). The objective of our study was to determine virus effects on plant vigor, and the spread of virus infection in the plants. Eight plants of each cultivar, four infected and four free of infection, were grown in pots on a gravel pad for the 2002 growing season, and samples of primocane and floricane leaves were …

Chromosomal Expression Of The Haemophilus Influenzae Hap Autotransporter Allows Fine-Tuned Regulation Of Adhesive Potential Via Inhibition Of Intermolecular Autoproteolysis, Doran L. Fink, Joseph W. St. Geme Iii

Open Access Publications

No abstract provided.

Population Briefs, Vol. 9, No. 3, Population Council

Population Briefs

IN THIS ISSUE: Broad survey of Pakistani youth completed | Egyptian working women's perceptions of marriage | Improved care increases contraceptive use | New population encyclopedia offers thorough review, reflects expanded scope of field | Transformation in world's cities explored | Unlocking the mechanism of androgen action

Forssman Synthetase Expression Results In Diminished Shiga Toxin Susceptibility: A Role For Glycolipids In Determining Host-Microbe Interactions, Sean P. Elliott, Min Yu, Huaijin Xu, David B. Haslam

Open Access Publications

No abstract provided.

Risk Factors For Stenotrophomonas Maltophilia Bacteremia In Oncology Patients: A Case-Control Study, Anucha Apisarnthanarak, Jennie L. Mayfield, Teresa Garison, Patricia M. Mclendon, John F. Dipersio, Victoria J. Fraser, Louis B. Polish

Open Access Publications

No abstract provided.

Risk Of Hospital-Acquired Legionnaires' Disease In Cities Using Monochloramine Versus Other Water Disinfectants, James D. Heffelfinger, Jacob L. Kool, Scott Fridkin, Victoria J. Fraser, Jeffrey Hageman, Jospeh Carpenter, Cynthia G. Whitney

Open Access Publications

No abstract provided.

The Epidemiology Of Vancomycin-Resistant Enterococcus Colonization In A Medical Intensive Care Unit, David K. Warren, Marin H. Kollef, Sondra M. Seiler, Scott K. Fridkin, Victoria J. Fraser

Open Access Publications

No abstract provided.

Virulence Genes And Neutral Dna Markers Of Helicobacter Pylori Isolates From Different Ethnic Communities Of West Bengal, India, Simanti Datta, Santanu Chattopadhyay, G. Balakrish Nair, Asish K. Mukhopadhyay, Jabaranjan Hembram, Douglas E. Berg, Dhira Rani Saha, Asis Khan, Amal Santra, S. K. Bhattacharya, Abhijit Chowdhury

Open Access Publications

No abstract provided.

Outlook Magazine, Fall 2003

Outlook Magazine

No abstract provided.

Response 2003, Seattle Pacific University

Seattle Pacific Alumni Magazines

No abstract provided.

American Gypsies: Immigration, Migration, Settlement, Katherine Bernice Stephens

Theses Digitization Project

The intent of this thesis is to provide new information about American Gypsy history, specifically migration, immigration and settlement in the United States.

A Distance-Learning Program To Serve Migrant Families, April Dawn Marone

Theses Digitization Project

The education of the children of migrant farmworkers is difficult to manage because of their mobile lifestyle. The dropout rate of these children is extremely high and remains the highest of any group in the United States. This project offers an historical overview of the creation and development of the migrant education programs of today. After examining sample distance learning programs and their important components, this project features a model distance-learning program for migrants. The goal is to create distance learning programs that will allow migrant children to continue school as they travel, guide them to graduation, and lead them …

Using Distance Learning To Enhance Cross-Listed Interdisciplinary Law School Courses, Paula E. Berg

Publications and Research

No abstract provided.

Bioterrorism Meets Privacy: An Analysis Of The Model State Emergency Health Powers Act And The Hipaa Privacy Rule, Julie Bruce

Annals of Health Law and Life Sciences

Ms. Bruce's paper analyzes the interplay between the Model State Emergency Health Powers Act and the HIPAA Privacy Rule. The article begins by examining specific relevant provisions of the Act and Rule. Next, it traces the history of public health law through the court system and then uses this foundation to discuss how the Model State Emergency Health Powers Act and the HIPAA Privacy Rule could co-exist, protecting Americans in the case of a bioterror attack, while being appropriately sensitive to the confidentiality of private health information.

Does Vancomycin Resistance Affect Outcome In Patients With Enterococcus Faecium Bacteremia?, Garth S. Herbert

Yale Medicine Thesis Digital Library

No abstract provided.

Ohio Northern University Catalog, 2003-2004, Ohio Northern University

University Catalogs

No abstract provided.

How Much Do Western Democracies Value Family And Marriage?: Immigration Law's Conflicted Answers, Nora V. Demleitner

Hofstra Law Review

No abstract provided.

Farm Disease Crises In The United Kingdom: Lessons To Be Learned, Michael C. Appleby

State of the Animals 2003

Over the last fifteen years, a diverse succession of disease-related crises has befallen farm animal and food industries in the United Kingdom. Some have involved animal health, with little risk to humans. Some have involved human health, with animals acting as a reservoir for infection but little affected themselves. Some, however— including the most alarming— have involved both animal and human health through zoonoses, diseases transmittable from animal to human. All of these crises are linked in the public mind and in many commentaries, and indeed there are issues that many of them share. The most common of these is …

Horse Welfare Since 1950, Katherine A. Houpt, Natalie Waran

State of the Animals 2003

There are approximately 6.9 million horses in the United States, more than in any other country in the world (American Horse Council 2000) (Table 1). That fact alone should inspire Americans to improve equine welfare, although it must be said that the state of domesticated horses is better now than it was fifty years ago.

At the turn of the millennium, the most pressing welfare issues of the domestic horse surround conditions found in slaughter and transport to slaughter; pari-mutuel racing; the pregnant mare urine (PMU) industry; the competitive and show industry; and in the development of husbandry-related stereotypes. (Urban …

Pain And Distress Associated With Polyclonal Antibody Production: Discussion And Recommendations, The Humane Society Of The United States

ANIMAL RESEARCH

The Humane Society of the United States (HSUS) held a workshop in August 2002 in order to develop recommendations for minimizing pain and distress associated with polyclonal antibody (Pab) production. A small group of experts in the fields of antibody production, animal welfare, in vitro alternatives, and/or regulatory compliance participated in the roundtable discussion. The workshop was a scientifically based meeting, and recommendations were based on the extensive experience of the workshop participants as well as published literature regarding the relevant issues.

Participants recognized that insufficient attention has been paid to animal welfare aspects of Pab production, in part because …

The State Of The Animals Ii: 2003, Deborah J. Salem

In this all new volume in the State of the Animals series, internationally known scholars and distinguished experts examine the challenges facing farm animals, shelter animals, and wildlife worldwide from religious, legal, educational, and strategic perspectives.

Cameron County/Matamoros At The Crossroads: Assets And Challenges For Accelerated Regional And Binational Development, David V. Gibson, Pablo Rhi-Perez, Margaret Cotrofeld, Oralia De Los Reyes, Mark Gipson, University Of Texas At Brownsville, Texas Southmost College, University Of Texas At Austin

Digital Books

Study of assets and challenges for knowledge-based economic development in the Lower Rio Grande Valley. Includes demographic, economic, and education data for the region, as well as results of a survey of government and business leaders concerning economic development strategy.

© 2003 by UTB-CBIRD and IC² Institute.

Ehrlichia Chaffeensis: A Prototypical Emerging Pathogen, Christopher D. Paddock, James E. Childs

Zoonotics and Wildlife Disease: Publications

In April 1986, a medical intern scanning the peripheral blood smear of a severely ill man with an unexplained illness observed peculiar intracytoplasmic inclusions in several of the patient’s monocytes. The patient described multiple tick bites sustained approximately 2 weeks earlier during a visit to a rural area in northern Arkansas, and a presumptive diagnosis of Rocky Mountain spotted fever had been made (104, 174). Clinicians and scientists subsequently identified these inclusions as clusters of bacteria belonging to the genus Ehrlichia, previously known in the United States solely as veterinary pathogens (174). Within the next 5 years, the organism …

Cd21-Positive Follicular Dendritic Cells A Possible Source Of PrpSc In Lymph Node Macrophages Of Scrapie-Infected Sheep, Lynn M. Herrmann, William P. Cheevers, William C. Davis, Donald P. Knowles, Katherine I. O'Rourke

Zoonotics and Wildlife Disease: Publications

Natural sheep scrapie is a prion disease characterized by the accumulation of PrP^Sc in brain and lymphoid tissues. Previous studies suggested that lymph node macrophages and follicular dendritic cells (FDC) accumulate PrP^Sc. In this study, lymph nodes were analyzed for the presence of PrP^Sc and macrophage or FDC markers using dual immunohistochemistry. A monoclonal antibody (mAb) to the C-terminus of PrP reacted with CD172a+ macrophages and CD21+ FDC processes in secondary follicles. However, a PrP N-terminus- specific mAb reacted with CD21+ FDC processes but not CD172a+ macrophages in secondary follicles. Neither the PrP N-terminus nor C-terminus-specific …

Immunohistochemical Detection And Distribution Of Prion Protein In A Goat With Natural Scrapie, Reginald A. Valdez, Matthew J. Rock, Anne K. Anderson, Katherine I. O'Rourke

Zoonotics and Wildlife Disease: Publications

Formalin-fixed, paraffin-embedded tissue sections from a 3-year-old female Angora goat suffering from clinical scrapie were immunostained after hydrated autoclaving using a monoclonal antibody (mAb, F99/ 97.6.1; IgG1) specific for a conserved epitope on the prion protein. Widespread and prominent deposition of the scrapie isoform of the prion protein (PrP^Sc) was observed in the brain, brainstem, spinal cord, retina, postganglionic neurons associated with parasympathetic ganglia of myenteric and submucosal plexuses, Peyer’s patches, peripheral lymph nodes, and pharyngeal and palatine tonsils. The goat was homozygous for PrP alleles encoding 5 octapeptide repeat sequences in the N-terminal region of the prion …

A Prion Protein Epitope Selective For The Pathologically Misfolded Conformation, Eustache Paramithiotis, Marc Pinard, Trebor Lawton, Sylvie Laboissiere, Valerie I. Leathers, Wen-Quan Zou, Lisa A. Estey, Julie Lamontagne, Marty T. Lehto, Leslie H. Kondejewski, Gregory P. Francoeur, Maria Papadopoulos, Ashkan Haghighat, Stephen J. Spatz, Mark Head, Robert Will, James Ironside, Katherine I. O'Rourke, Quentin Tonelli, Harry C. Ledebur, Avi Chakrabartty, Neil R. Cashman

Zoonotics and Wildlife Disease: Publications

Conformational conversion of proteins in disease is likely to be accompanied by molecular surface exposure of previously sequestered amino-acid side chains. We found that induction of β-sheet structures in recombinant prion proteins is associated with increased solvent accessibility of tyrosine. Antibodies directed against the prion protein repeat motif, tyrosine-tyrosinearginine, recognize the pathological isoform of the prion protein but not the normal cellular isoform, as assessed by immunoprecipitation, plate capture immunoassay and flow cytometry. Antibody binding to the pathological epitope is saturable and specific, and can be created in vitro by partial denaturation of normal brain prion protein. Conformation-selective exposure of …

Properties Of A Disease-Specific Prion Probe, Guy Gorochov, Jean-Phillippe Deslys, Eustache Paramithiotis, Marc Pinard, Trebor Lawton, Sylvie Laboissiere, Valerie L. Leathers, Wen-Quan Zou, Lisa A. Estey, Julie Lamontagne, Marty T. Lehto, Leslie H. Kondejewski, Gregory P. Francoeur, Maria Paoadopoulos, Ashkan Haghighat, Stephen J. Spatz, Mark Head, Robert Will, James Ironside, Katherine I. O'Rourke, Quentin Tonelli, Harry C. Ledebur, Avi Chakrabartty, Neil R. Cashman

Zoonotics and Wildlife Disease: Publications

In a recently published article, Paramithiotis et al. describe antibodies specific for the prion Tyr-Tyr-Arg (YYR) repeat motif. These antibodies interact with the pathological isoform of the prion protein (PrP^SC), but not with the normal cellular isoform (Prp^C). Because of this restricted specificity, they suggest that YYR-specific antibodies could be useful for the diagnosis and treatment of prion diseases (Fig. O. The monoclonal antibodies, all of the IgM isotype, were produced by immunizing mice with a synthetic peptide (CYYRRYYRYY). When coupled to magnetic beads, these YYR-specific antibodies immunoprecipitate Prp^sc much more efficiently than Prp^{C …}