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Articles 481 - 510 of 73648
Full-Text Articles in Entire DC Network
Investigating Burnout Among Hospital Social Workers: A Qualitative Exploration, Crystal Marie Herring
Investigating Burnout Among Hospital Social Workers: A Qualitative Exploration, Crystal Marie Herring
Walden Dissertations and Doctoral Studies
No abstract provided.
Programmes That Integrate Parenting Support And Financial Well-Being Support: A Systematic Scoping Review, Eleanor F. Bryant, Morwenna Rogers, Amy Bond, Georgia Smith, Rebecca Summers, James Hall, Kristin Liabo, Iain Lang, Vashti Berry, Nick Axford
Programmes That Integrate Parenting Support And Financial Well-Being Support: A Systematic Scoping Review, Eleanor F. Bryant, Morwenna Rogers, Amy Bond, Georgia Smith, Rebecca Summers, James Hall, Kristin Liabo, Iain Lang, Vashti Berry, Nick Axford
Peninsula Medical School
Childhood experiences of economic disadvantage have harmful and long-lasting effects on child health. Early intervention can reduce some harms but it is unclear whether addressing economic disadvantage alongside psychosocial support yields additional benefits. This systematic scoping review aimed to identify evaluated programmes that integrate parenting support (PS) and financial well-being support (FWbS) for parents of children aged 0–19. The objectives were to describe programmes, relevant components, evaluation designs and impact on outcomes, and to consider if any programmes merit replication and testing in a UK context. Outcome or implementation evaluations of integrated PS and FWbS programmes published in English were …
The Shorthorn: October 26, 1983
The Shorthorn: October 26, 1983
The Shorthorn Newspaper Collection: 1980s
No abstract provided.
The Shorthorn: September 8, 1983
The Shorthorn: September 8, 1983
The Shorthorn Newspaper Collection: 1980s
No abstract provided.
The Shorthorn: March 23, 1983
The Shorthorn Newspaper Collection: 1980s
No abstract provided.
The Top 50 Cited Articles In Pediatric Neurology: A Bibliometric Analysis, Anas Alyazidi, Osama Muthaffar, Ahmed Bamaga, Hebah Qashqari, Abdulmalek Alhithlool, Ahmad Alanezi, Sameer Almehmadi, Mohamed Babiker, Fahad Bashiri
The Top 50 Cited Articles In Pediatric Neurology: A Bibliometric Analysis, Anas Alyazidi, Osama Muthaffar, Ahmed Bamaga, Hebah Qashqari, Abdulmalek Alhithlool, Ahmad Alanezi, Sameer Almehmadi, Mohamed Babiker, Fahad Bashiri
Neurosciences
Objectives: To identify and analyze the most influential articles within the field of pediatric neurology through a bibliometric lens. As pediatric neurology continues to expand across subspecialties, identifying landmark studies is critical for understanding clinical and research priorities. Bibliometric analysis enables the evaluation of citation trends to highlight impactful contributions that have shaped the field.
Method: A bibliometric analysis of the 50 most-cited pediatric neurology articles was conducted. Articles were assessed by citation metrics, study design, subspecialty, journal impact factor (JIF), and funding status. Correlation and regression analyses evaluated associations between variables.
Results: Citation counts ranged from 185 to 1,440 …
(R2167) Global Stability Of Seirs Model With Single Dose Vaccination In Varying Population, Govind Jha, Prabhat Mandal, Sarita Jha
(R2167) Global Stability Of Seirs Model With Single Dose Vaccination In Varying Population, Govind Jha, Prabhat Mandal, Sarita Jha
Applications and Applied Mathematics: An International Journal (AAM)
Understanding the evolution of infectious diseases within a dynamic population is essential for formulating effective public health strategies. This work introduces an enhanced SEIRS epidemic model that incorporates demographic variation and a single-dose vaccination strategy, supporting that immunity can be reduced over time. The model reflects diseases in which individuals may return to the susceptible state after recovery. Extending prior reduced three-dimensional models, this study develops a complete four-dimensional SEIRS framework, thereby increasing the model’s applicability to real-world scenarios. The inclusion of the full system presents greater analytical challenges. To overcome this, we extend the second additive compound matrix and …
(R2124) Impact Of Delay And Awareness On Hiv/Aids Epidemic Model, Debashis Biswas
(R2124) Impact Of Delay And Awareness On Hiv/Aids Epidemic Model, Debashis Biswas
Applications and Applied Mathematics: An International Journal (AAM)
A delayed HIV/AIDS epidemic model with awareness has been taken here. Essentially, it is mentioned that the disease spreads among the population only through contact (horizontal transmission). The equilibrium points of both the proposed models are investigated, and their stability is discussed. Both models have two types of equilibria, namely the disease-free and the disease positive. The basic reproductive number of both models has been calculated by using the next generation matrix technique. In this paper, the main motivation is to find a way to decrease the disease transmission. Also discussed the impact of delay and awareness on the HIV/AIDS …
Racial Differences In Hiv Testing And Hiv Infection Among Adults With Seborrheic Dermatitis In Atlanta, Georgia, Olivia Elizabeth Collins
Racial Differences In Hiv Testing And Hiv Infection Among Adults With Seborrheic Dermatitis In Atlanta, Georgia, Olivia Elizabeth Collins
Walden Dissertations and Doctoral Studies
No abstract provided.
Exploring Pediatric Leprosy In An Endemic Area: Case Series Of Eight Patients In Indonesia, Gitalisa Andayani Adriono, Tri Rahayu, Sri Linuwih Sw Menaldi, Nelfidayani Nelfidayani, Retno Sulistyo Wardani, Kahlil Gibran, Malika Sabrina Yunifananda, Kartika Qonita Putri, Yunia Irawati
Exploring Pediatric Leprosy In An Endemic Area: Case Series Of Eight Patients In Indonesia, Gitalisa Andayani Adriono, Tri Rahayu, Sri Linuwih Sw Menaldi, Nelfidayani Nelfidayani, Retno Sulistyo Wardani, Kahlil Gibran, Malika Sabrina Yunifananda, Kartika Qonita Putri, Yunia Irawati
Journal of General - Procedural Dermatology and Venereology Indonesia
Background: Leprosy remains a significant public health concern in endemic regions such as Indonesia. Children are particularly vulnerable due to their naive immunity and close familial contacts. This study aims to report cases of pediatric leprosy in Lembata, Indonesia, focusing on clinical characteristics and associated risk factors.
Case Illustration: A case series of eight pediatric patients (<15 >years) diagnosed with leprosy was conducted during a community-based screening program in Lembata, Indonesia, in 2022. Of 140 individuals examined, 8 were children. Most patients were male (6/8) with a mean age of 11.75 years. Multibacillary (MB) leprosy predominated (7/8), and a history …15>
Substance Use From Adolescence To Midlife: The Influence Of Religiosity, Childhood Aversity, And Sexual Minority Status, Joshua Glenn Grove
Substance Use From Adolescence To Midlife: The Influence Of Religiosity, Childhood Aversity, And Sexual Minority Status, Joshua Glenn Grove
Dissertations - ALL
Substance use is a leading cause of premature mortality in the United States, with overdose and alcohol-related deaths rising sharply in adulthood and midlife. Religiosity is among the most well-documented social factors associated with lower substance use, operating through community ties, behavioral norms, and meaning-making. Yet despite the life course nature of substance use, research has centered primarily on adolescence, relied on cross-sectional data, and typically employed single measures of religiosity. Consequently, it remains unclear whether religiosity functions similarly across its multiple dimensions or among populations exposed to heightened social disadvantage, including individuals with adverse childhood experiences (ACEs) and sexual …
Knowledge, Attitudes, And Practice Of Iraqi Parents Regarding The Issues Of Vaccinating Their Children, Taqi Mohammed Jwad Taher, Rami Bahaa Saadi, Rand Sadik Al Radhy, Mohanad Aljama, Houreleen H Salman, Mayameen H Salman, Mustafa Sabeeh Lafta Zubaidi, Shaymaa Abdul Lateef Al-Fadhul, Mohammed Firas Turki, Hasanain Faisal Ghazi
Knowledge, Attitudes, And Practice Of Iraqi Parents Regarding The Issues Of Vaccinating Their Children, Taqi Mohammed Jwad Taher, Rami Bahaa Saadi, Rand Sadik Al Radhy, Mohanad Aljama, Houreleen H Salman, Mayameen H Salman, Mustafa Sabeeh Lafta Zubaidi, Shaymaa Abdul Lateef Al-Fadhul, Mohammed Firas Turki, Hasanain Faisal Ghazi
Muthanna Medical Journal
Background: Children's vaccination can help in the prevention and protection against various fatal illnesses. Aims: This study aims to assess the knowledge, attitudes, and practices of both parents toward their children's vaccinations. Methods: This is a cross-sectional analytical study of Iraqi parents in Wasit province. Data was collected through self-administered questionnaires that were developed from published research and adapted according to local culture. Data was collected from three primary health care centres in Kut City, Wasit province, for 255 parents who visited centres with their children for any reason from the first of April 2023 to the thirteenth of July …
Near-Infrared Spectroscopy For Monitoring Bovine Respiratory Syncytial Virus Infection In Experimentally Challenged Calves, Erin Blanchard, Jelena Muncan, Grace Beddingfield, Cassandra Barber, Florencia Meyer, Santiago Cornejo, Merrilee Thoresen, Amelia Woolums, Carrie Vance
Near-Infrared Spectroscopy For Monitoring Bovine Respiratory Syncytial Virus Infection In Experimentally Challenged Calves, Erin Blanchard, Jelena Muncan, Grace Beddingfield, Cassandra Barber, Florencia Meyer, Santiago Cornejo, Merrilee Thoresen, Amelia Woolums, Carrie Vance
Endeavors: Mississippi State Undergraduate Research Journal
Bovine respiratory disease (BRD) is a multifactorial disease complex that causes significant economic loss in the cattle industry. Bovine respiratory syncytial virus (BRSV), one of the primary viruses included in BRD, primarily targets the lower respiratory tract and causes a wide variety of subclinical and clinical signs. Current diagnosis techniques require off-site laboratory testing, creating delays that allow BRSV to spread through herds and highlighting the need for rapid diagnostic methods. The objective of the study was to evaluate near-infrared spectroscopy as a diagnostic tool for BRSV detection across varying infection severities. Twenty-two Holstein bull calves were reared in research …
Prevalence And Genotypes Of Enterocytozoon Bieneusi In Captive Wild Hedgehogs (Erinaceus Amurensis) In China, Guo-Liang Chen, Yu-Lin Zhou, Xin Liu, Ming Shu, Can Yin
Prevalence And Genotypes Of Enterocytozoon Bieneusi In Captive Wild Hedgehogs (Erinaceus Amurensis) In China, Guo-Liang Chen, Yu-Lin Zhou, Xin Liu, Ming Shu, Can Yin
The Thai Journal of Veterinary Medicine
Enterocytozoon bieneusi is now recognised as an emerging pathogen, which can cause a series of intestinal diseases in humans and animals. However, limited information is available about the occurrence of E. bieneusi in hedgehogs. In this study, a total of 205 fecal samples of captive wild hedgehogs (Erinaceus amurensis) were collected from two wildlife conservation centers in Henan and Anhui provinces, China. Genomic DNA was extracted from the stool samples and screened by nested PCR targeting the internal transcribed spacer (ITS) sequences. The overall prevalence of E. bieneusi in captive wild hedgehogs was 44.4% (91/205). Five zoonotic genotypes were identified, …
Implementasi Lean Management Untuk Efisiensi Pengelolaan Linen Dan Kesesuaian Standar Pencegahan Dan Pengendalian Infeksi Di Rsu X, Rionugrah Sari, Alih Germas Kodyat, Apri Sunadi
Implementasi Lean Management Untuk Efisiensi Pengelolaan Linen Dan Kesesuaian Standar Pencegahan Dan Pengendalian Infeksi Di Rsu X, Rionugrah Sari, Alih Germas Kodyat, Apri Sunadi
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Linen management is an important process in hospitals that is directly related to service quality and Infection Prevention and Control (IPC) efforts. This study aimed to analyze the implementation of Lean Management in linen management at the laundry unit of RSU X and to evaluate its contribution to improving process efficiency and strengthening IPC practices. The study employed an operational research design with a qualitative approach through observation, in-depth interviews, and document review. Data analysis was conducted using Value Stream Mapping, waste identification based on the eight waste concept, and root cause analysis using the 5 Whys method. The results …
Laminarin-Loaded Solid-In-Oil Nanodispersion For Enhanced Non-Invasive Transdermal Immunization, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie C. Wakabayashi, Noriho J. Kamiya, Muhammad Moniruzzaman, Masahiro Goto
Laminarin-Loaded Solid-In-Oil Nanodispersion For Enhanced Non-Invasive Transdermal Immunization, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie C. Wakabayashi, Noriho J. Kamiya, Muhammad Moniruzzaman, Masahiro Goto
Publications and Research
Simple and non-invasive transdermal vaccination is an attractive alternative to conventional injection-based immunization. However, the effectiveness of transdermal vaccines is often constrained by the stratum corneum barrier. Although the use of solid-in-oil (S/O) nanodispersion technology has successfully facilitated skin permeation to induce an immunological response, the antibody titers remain suboptimal. Herein, a dectin-1 selective ligand, laminarin, was used as an immunostimulatory adjuvant to enhance the immune response. S/O nanodispersions loaded with laminarin and ovalbumin (OVA) were systematically developed and characterized in terms of particle size, in vitro OVA release behavior, and skin permeation performance using excised mouse skin. In vivo …
Exploring The Determinants Of Operating Room Utilization: A Scoping Review Of Influential Factors In Surgical Efficiency, Isma Sari Chumairah, Masyitoh Basabih
Exploring The Determinants Of Operating Room Utilization: A Scoping Review Of Influential Factors In Surgical Efficiency, Isma Sari Chumairah, Masyitoh Basabih
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Optimal utilization of the operating room (OR) is a crucial element in improving the efficiency of surgical services and hospital performance. This scoping review aimed to identify and map the factors influencing OR utilization based on recent scientific literature. We conducted a scoping review using the Population–Concept–Context (PCC) framework and reported it according to the PRISMA-ScR guidelines. We systematically searched PubMed, Scopus, and ScienceDirect for articles published between 2015 and 2025. Eligible studies were screened, and information on study characteristics and reported determinants of OR utilization was extracted and summarized descriptively. Forty studies were included. The reported determinants clustered into …
Healthcare Emergency Management Salary Survey Analysis, Grace Elizabeth Thiel, Anna C. Hansen, Sharon J. Meaker-Medcalf, Rex Archer, Keith F. Hansen
Healthcare Emergency Management Salary Survey Analysis, Grace Elizabeth Thiel, Anna C. Hansen, Sharon J. Meaker-Medcalf, Rex Archer, Keith F. Hansen
Faculty and Staff Publications
Background: The field of emergency preparedness is often considered a limitedly recognized aspect of healthcare; however, it serves an integral component of patient and worker safety. While an important field, there is limited data focused on the field pertaining to salaries of workers, resources utilized and produced, and the typical working environment. The purpose of this project was to assess salary and other demographic markers of healthcare emergency preparedness professionals in the United States.
Methods: The project compared salary, full-time equivalent levels, preparedness program budgets, and respondent demographic markers across the country via a survey that was administered for a …
Effectiveness Of Lay Workers Delivering Behavioural Activation For People With Depression: Systematic Review And Meta-Analysis, Shwikar Othman, Lauren Blekkenhorst, Asangaedem Akpan, Irene Ngune, Nilufeur Mckay, Alison Kennedy, Elizabeth Armstrong, Michael Hunter, Kevin Murray, Mathew Coleman, Richard Gray, Emma Jones, Christopher Lee, Martin Jones
Effectiveness Of Lay Workers Delivering Behavioural Activation For People With Depression: Systematic Review And Meta-Analysis, Shwikar Othman, Lauren Blekkenhorst, Asangaedem Akpan, Irene Ngune, Nilufeur Mckay, Alison Kennedy, Elizabeth Armstrong, Michael Hunter, Kevin Murray, Mathew Coleman, Richard Gray, Emma Jones, Christopher Lee, Martin Jones
Research outputs 2022 to 2026
Background Behavioural activation is effective for depression, but its effectiveness in treating adults with depression when delivered by lay workers remains unclear. Aims To examine the effectiveness of behavioural activation delivered by lay workers, compared with any control group, in reducing depressive symptoms in adults. Method This systematic review searched six databases from inception to January 2025, for randomised controlled trials (RCTs) comparing behavioural activation and any control conditions for individuals with depression when delivered by lay workers. Additional searches were conducted in the international trial registries and reference lists (PROSPERO registration CRD42024625620). Risk of bias was assessed using the …
House Sparrow Invasion Success Across Ecological, Immunological, And Molecular Scales, Kailey Marie Mccain
House Sparrow Invasion Success Across Ecological, Immunological, And Molecular Scales, Kailey Marie Mccain
USF Tampa Graduate Theses and Dissertations
Biological invasions offer natural experiments for studying how organisms cope with ecological novelty. Although invasion success is often attributed to enemy release, introduced organisms do not enter enemy-free environments. Instead, they enter heterogeneous landscapes in which some familiar enemies are absent, others remain, and entirely novel enemies may be encountered. The question, then, is how invaders (hereafter non-natives) are poised to respond to these threats? This dissertation examines whether successful invasions in house sparrows (Passer domesticus) is associated with shifts in pathogen exposure, immune dynamics in blood, gut physiology, and gene co-expression network structure.
Chapter 1 is at the population/ecological …
Association Of Social Isolation, Loneliness, Social Strain And Support With Cancer Onset, And Frailty And All-Cause Mortality In People With Cancer, Joanne Elayoubi
Association Of Social Isolation, Loneliness, Social Strain And Support With Cancer Onset, And Frailty And All-Cause Mortality In People With Cancer, Joanne Elayoubi
USF Tampa Graduate Theses and Dissertations
Cancer is the second leading cause of death both in the United States and globally and for individuals over sixty-five. In 2026, approximately 2,114,850 new cancer cases are projected to emerge according to the National Center for Health Statistics (Siegel et al., 2026). Cancer incidence is increasing, making older adults sixty-five and older at risk of frailty and mortality following cancer. Although social isolation, loneliness, lack of social support, and social strain have been found to be risk factors for poor health and mortality, it is not clear the extent to which social relationships are associated with incident cancer, and …
Covid-19'S Impact On Student Behavior In Rural-Urban Fringe Elementary Schools, Chanel V. Leslie
Covid-19'S Impact On Student Behavior In Rural-Urban Fringe Elementary Schools, Chanel V. Leslie
College of Education
This study examines the impact of COVID-19 on student behavior in rural-urban fringe schools in Northern Alabama. The qualitative narrative inquiry research centers the lived experiences of teachers from four different schools as they navigate and explain this shift during this time. Grounded in Bronfenbrenner's (1979) ecological systems theory, the study is guided by three research questions that address the changes in student behavior and classroom dynamics; teacher preparedness and the ability to manage post-pandemic behavioral challenges; and effective interventions and support strategies. This research offers further insight into the erosion of foundational social skills, widespread emotional dysregulation, and patterns …
Knowledge And Practices Of Iraqi Pediatricians Regarding Antibiotic-Associated Diarrhea, Nabeeha Najatee Akram, Shaymaa Khalid Abdulqader, Maha Majeed Hameed
Knowledge And Practices Of Iraqi Pediatricians Regarding Antibiotic-Associated Diarrhea, Nabeeha Najatee Akram, Shaymaa Khalid Abdulqader, Maha Majeed Hameed
Muthanna Medical Journal
Objectives: This study aims to assess the knowledge of pediatricians regarding antibiotic-associated diarrhea (AAD) and explore their practices with prevention and treatment of AAD.
Patients and method: A cross-sectional, questionnaire-based study enrolled Iraqi pediatricians. A structured self-administered questionnaire was constructed based on a comprehensive review of current literature and ESPIGAN guidelines relevant to AAD. The questionnaire consists of three parts: the first part consists of six questions about the clinical and demographical characteristics of pediatricians, including age, sex, title (Qualification), years of experience in pediatrics, affiliation, and province of work. The second part consists of 12 closed-ended questions with each …
Failure To Communicate: A Method To Improve Osha And Fsis Collaboration In Meat And Poultry Plants, Ty Haralson
Failure To Communicate: A Method To Improve Osha And Fsis Collaboration In Meat And Poultry Plants, Ty Haralson
Journal of Food Law & Policy
In its 2024 annual report, the GAO recognized the overlapping functions of the Occupational Safety and Health Administration (“OSHA”) and the Food Safety and Inspection Service (“FSIS”) in meat and poultry plants and how the two agencies have failed to effectively collaborate. Although both FSIS and OSHA have vested interests in ensuring healthy environments in meat and poultry plants, the administrative agencies have not developed a thorough approach for collaboration.
Created after the passage of the Williams-Steiger Occupational Safety and Health Act of 1970, OSHA’s primary responsibility is to “ensur[e] safe and healthful working conditions . . . ” in …
Continuing Medical Education As A Workforce Learning System For Artificial Intelligence In Clinical Practice, Tim Murphy, Rob E. Carpenter
Continuing Medical Education As A Workforce Learning System For Artificial Intelligence In Clinical Practice, Tim Murphy, Rob E. Carpenter
Human Resource Development Faculty Publications and Presentations
Artificial intelligence (AI) is increasingly embedded in clinical decision support, documentation, imaging, predictive analytics, and workflow management. However, the educational systems responsible for preparing practicing physicians to use AI have not fully addressed the interpretive, ethical, and organizational demands of AI-supported care. This qualitative case study examined how continuing medical education (CME) shapes physicians’ readiness to integrate AI into clinical practice. Guided by the Unified Theory of Acceptance and Use of Technology (UTAUT) and human resource development (HRD), the study analyzed semi-structured interviews with 14 physicians from diverse specialties within a large academic health system. Organizational artifacts, including CME announcements, …
June 23, 2026 Ereporter, University Of Alabama At Birmingham
June 23, 2026 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Promiscuous Mutualisms: John Dupré And The Centrality Of Symbiosis In The Living World, Thomas Pradeu
Promiscuous Mutualisms: John Dupré And The Centrality Of Symbiosis In The Living World, Thomas Pradeu
Presidential Fellows Articles and Research
My goal in this chapter is to show that symbiosis, especially symbiotic interactions between ‘macrobes’ (non-microbial organisms) and microbes, is a central topic in John Dupré’s work. This topic is undeniably one of the topics by which Dupré has gained wide recognition among practicing scientists, in addition to his recognition within the philosophical community. I spell out why symbiosis has turned out to be a sort of ideal trope for Dupré, as it encapsulates many of his main personal themes—from promiscuous realism to process ontology. I then show that immunology offers one interesting and complementary entry point into microbial symbiosis …
Knowledge, Attitudes And Dispensing Practices Regarding Antimicrobial Resistance And Stewardship: A Comparative National Assessment Among Primary Healthcare Pharmacists In Oman, Mohammed Al Ghafari, Meher Rizvi, Hana Al Ghusaini, Zaima Al Rawahi, Wafa Al Balushi, Manal Al Ghafri, Hamed Al-Qanubi, Zuhair Al Salti, Idris Al Jumaa, Muhammed Rafiq
Knowledge, Attitudes And Dispensing Practices Regarding Antimicrobial Resistance And Stewardship: A Comparative National Assessment Among Primary Healthcare Pharmacists In Oman, Mohammed Al Ghafari, Meher Rizvi, Hana Al Ghusaini, Zaima Al Rawahi, Wafa Al Balushi, Manal Al Ghafri, Hamed Al-Qanubi, Zuhair Al Salti, Idris Al Jumaa, Muhammed Rafiq
Sultan Qaboos University Medical Journal
Objectives: Antimicrobial resistance (AMR) is driven by inappropriate antibiotic use. This study aimed to assess the knowledge, attitudes and dispensing practices (KAP) regarding AMR and antimicrobial stewardship (AMS) among primary healthcare (PHC) pharmacists and assistant pharmacists in Oman. Furthermore, the study sought to compare these parameters across facilities with historically high versus standard antibiotic consumption to identify structural determinants of AMS.
Methods: This national cross-sectional study was conducted among PHC pharmacy staff in February 2025. KAP were assessed via a structured electronic questionnaire. Data were analysed using generalized estimating equation models to identify KAP predictors while accounting for facility-level …
Photoluminescent Studies Of Metal-Organic Frameworks For Small Molecule Sensing, Julia T. Dematteo
Photoluminescent Studies Of Metal-Organic Frameworks For Small Molecule Sensing, Julia T. Dematteo
USF Tampa Graduate Theses and Dissertations
Metal–organic frameworks (MOFs) are highly tunable nanoporous materials with broad applications in gas separation, drug delivery, light harvesting, and chemical sensing. The incorporation of photoactive components into MOFs enables the development of optical sensors capable of detecting a wide range of analytes. Porphyrins and metalloporphyrins are particularly attractive for such applications due to their high molar absorptivity, strong emission quantum yields, and versatile interactions with chemical species.
In this work, two porphyrinic MOFs, PCN-222 and MOF1(Cd), are investigated. Both frameworks utilize tetrakis(4-carboxyphenyl)porphyrin (TCPP) as the organic linker, imparting optical functionality to the materials. Integration of TCPP into the framework induces …
Ion Channels As Targets For Parasiticides: A Brief Review Of Past, Present, And Future Directions, Josette V. Ricker, Mallory Mendenhall
Ion Channels As Targets For Parasiticides: A Brief Review Of Past, Present, And Future Directions, Josette V. Ricker, Mallory Mendenhall
Georgia Journal of Science
Scientists and healthcare providers have tried for decades to find parasite treatments that balance patient safety with efficacy in eliminating the pathogen. One approach is to target specifically the parasite’s important bodily functions while sparing the host. This brief review examines the historically significant antiparasitics - pyrethrins, picrotoxin, piperazine, and avermectins – all which specifically target parasite ion channels. We discuss the history of their discovery and use, which subsequently led to the development of new generations of parasiticides, and continues to inspire the search for safe and effective treatments.