Digital Commons Network^™

Coping With Human Immunodeficiency Disease As Predictor Of Adherence With Antiretroviral Medication, Saurabh Mistry

Open Access Master's Theses

Infection by Human Immunodeficiency Virus (HIV) is a multifactor disease process in which the patient must confront an array of physiological, sociocultural, economic, and psychological stressors that have the collective potential for triggering major stress responses and psychological dysfunction. People's reactions to and the outcomes of traumatic events are mediated by their subjective style of coping. Coping is defined as a person's "constantly changing cognitive and behavioral efforts to manage specific external and internal demands that are appraised as taxing or exceeding the resources of a person". Coping, an important psychological construct has been shown to affect outcomes such as …

Complete Analysis Of The B‐Cell Response To A Protein Antigen, From In Vivo Germinal Centre Formation To 3‐D Modelling Of Affinity Maturation, Cl Adams, Mkl Macleod, Milner‐White E James, R Aitken, P Garside, Di Stott

Peninsula Medical School

SummarySomatic hypermutation of immunoglobulin variable region genes occurs within germinal centres (GCs) and is the process responsible for affinity maturation of antibodies during an immune response. Previous studies have focused almost exclusively on the immune response to haptens, which may be unrepresentative of epitopes on protein antigens. In this study, we have exploited a model system that uses transgenic B and CD4+ T cells specific for hen egg lysozyme (HEL) and a chicken ovalbumin peptide, respectively, to investigate a tightly synchronized immune response to protein antigens of widely differing affinities, thus allowing us to track many facets of the development …

Relationship Between The Knowledge Of Sexually Transmitted Disease And Sexual Behavior, Kong Chen

Dissertations and Theses @ UNI

Undergraduate college students, despite widespread prevention and education efforts, still engage in sexual behaviors that place them at risk of sexually transmitted diseases (STDs). The hypothesis of the study was that higher levels of knowledge of STDs were associated with positive sexual behavior. Thus, sexual behavior, knowledge of STDs, and the relationship between those two aspects among 103 undergraduate students (70 women and 33 men) at the University of Northern Iowa (UNI) were examined in the study.

No statistical significance was found in terms of college students' knowledge of STDs and their sexual behavior. This study showed that female students …

Effects Of Nitrates/Nitrites On Lymphocyte Proliferation And Cytokine Production, Lu Fang

Dissertations and Theses @ UNI

Approximately 3 million people may be exposed to high nitrate levels(>10 ppm) in the United States, especially in Iowa and other agricultural states. The concern regarding usage of groundwater with excessive concentrations of nitrates is related to human health effects. The toxicity of nitrate to humans is due to the body's reduction of nitrate to nitrite. Nitrate/nitrite impair public health with consequences such as gastric cancer, methemoglobinemia and other diseases. Currently, based upon human case studies, the drinking water quality standard in the U.S. is 10 ppm nitrate-N (MCL). Little work has been done on the effects of nitrate/nitrite …

Labor And Employement Law - Discrimination: An Eeoc Regulation Allowing Employers To Assert That Employee May Not Pose A Danger To Himself Falls Within The Purview Of The Americans With Disabilities Act, Erin M. Conroy

North Dakota Law Review

No abstract provided.

Blinded By Bioterrorism: Public Health And Liberty In The 21st Century, George J. Annas

Faculty Scholarship

In Blindness, Nobel Prize laureate Jos6 Saramago chronicles the quarantining of the first victims of a plague of blindness.1 We meet many people who become blind in Saramago's novel, including an opthamologist, a one-eyed man with an eye patch, and a man born blind. Saramago reminds us that we are all blind in one way or another, and that there are many things about ourselves and our society that we can't or won't see. The quarantine itself turns out to be isolating, inhumane, and degrading; the interred blind being portrayed by themselves and others as pigs, dogs, and "lame crabs." …

The Right To Health And The Nevirapine Case In South Africa, George J. Annas

Faculty Scholarship

Thanks to activists in South Africa, the right to health as a human right has returned to the international stage, just as it was being displaced by economists who see health through the prism of a globalized economy and by politicians who see it as an issue of national security or charity. The current post-apartheid debate in South Africa is not about race but about health, and in this context, the court victory by AIDS activists in the nevirapine case has been termed not only, as stated in one British newspaper, “the greatest defeat for [President Thabo] Mbeki's government” but …

Puppy Love: Bioterrorism, Civil Rights, And Public Health, George J. Annas

Faculty Scholarship

Florida has been the state humorists most like to make fun of since the 2000 presidential election, especially when it comes to politics. And humorists are almost the only commentators who can be counted on to tell us the truth about the state of American politics today. When Californians decided to recall their Governor, for example, Conan O'Brien observed: "Yesterday Arnold Schwarzenegger announced he would run for governor of California. The announcement was good news for Florida residents, who now live in the second-flakiest state in the country."' And when more than 200 people filed to run for Governor, Jay …

Drug Wars In Black And White, Joseph E. Kennedy

Faculty Publications

No abstract provided.

Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena

LSU Doctoral Dissertations

To study the protective responses of cyathostome-infected ponies, two challenges were performed employing animals with different histories of exposure to these parasites. The hypothesis developed and to be tested in these experiments was that ponies that had longer exposure to cyathostome contaminated pastures would express acquired resistance to infection. The assumption behind this hypothesis was that helminth-naïve ponies infected with cyathostomes would eliminate the infection using only innate immune responses. Whereas previously exposed ponies would eliminate the infection with acquired immune responses, and these would be more effective in ponies with longer exposure to cyathostomes. Thus, helminth-naïve animals would acquire …

Immunological, Hematological, And Serum Biochemical Effects Of High Level Dietary Fish Oil And Vitamin E Supplementation In The Dog, Casey J. Leblanc

LSU Doctoral Dissertations

Inflammation is a component of the innate immune response. However, severe or prolonged inflammation can be detrimental. Dietary n-3 fatty acid supplementation has proven clinical benefits in chronic inflammatory diseases, most likely due to reduced synthesis of inflammatory mediators and inhibition of lymphocyte proliferation and function. The purposes of this study were to characterize alterations in inflammatory mediator production, and lymphocyte proliferation, in dogs fed a diet consisting of 0.65% n-3 fatty acids (DMB) with an n-6:n-3 fatty acid ratio of 3.4:1. Fifteen dogs were randomly assigned to one of three dietary groups for twelve weeks. Group Sunflower oil received …

The Epidemiology Of Shiga-Toxigenic Escherichia Coli O157:H7 In Louisiana Cattle, And White-Tailed Deer, John Robert Dunn

LSU Doctoral Dissertations

Shiga-toxigenic Escherichia coli (STEC) O157:H7 is an important human pathogen. Dairy cattle, beef cattle, and white-tailed deer (WTD) are involved in STEC O157:H7 transmission to humans. We conducted cross-sectional studies in Louisiana, using sensitive microbiological methods, in dairy cattle, beef cattle, and WTD to investigate the epidemiology of STEC O157:H7. Results of the dairy studies are as follows. In the point prevalence study, summer-time prevalence in herds was 38.5%, with a cow-level prevalence of 6.5%. Among positive herds, cow-level prevalence ranged from 3%-34.6%. Three of five herds sampled in the longitudinal study were positive. Cow-level prevalence increased during spring and …

Optimization And Automation Of A Thermal Oyster Shucking Process, Daniel Edgar Martin

LSU Doctoral Dissertations

Louisiana Gulf Coast oysters (Crassostrea virginica) were subjected to thermal shucking treatments to effect adductor muscle release from both left and right valves. The oysters were instrumented with thermocouples to monitor and record process temperatures in the oysters and on the shell. Following treatment, the oysters were evaluated for relaxation and release of the adductor muscle, meat quality and texture, and for the effect of the treatments on the storage life of the oysters as measured by total microbial plate counts. The treatments of many oysters resulted in a complete release of the adductor muscle from the shell while maintaining …

Susceptibility Of Bacillus Anthracis To Gamma And Cherry Bacteriophage, Preston A. Fulmer

LSU Master's Theses

Bacillus anthracis is a bacterium that causes severe disease mainly in ruminants, but can affect any mammal, including humans. A popular method for the detection of this organism is susceptibility of the bacterial isolate to g bacteriophage. However, to date no study on the resistance of a wide variety of B. anthracis isolates has been conducted. The following study examines the rate of resistance of a wide range of B. anthracis isolates to g phage as well as another phage specific for B. anthracis known as Cherry phage. We also compared susceptibility to phage with another detection method, susceptibility to …

Psychosocial Predictors Of Visceral Adiposity, Paula C. Rhode

LSU Doctoral Dissertations

Psychosocial factors are thought to influence health through primarily direct physiological mechanisms or the alteration of health related behaviors. Three factors hypothesized to negatively impact health include arousal, life stress, and depressive symptomatology. One recent theorist suggests that the interaction between psychological stress and stress hormones on the neuroendocrine system may result in adverse changes to body composition, most notably the increased deposition of visceral adipose tissue (Bjorntorp, 1993). The current study prospectively examined the relationship between self-reported stressful life events, depressive symptoms and trait arousal on the deposition of visceral fat, as measured by computerized tomography (CT). Subjects were …

Public Health And National Security In The Global Age: Infectious Diseases, Bioterrorism, And Realpolitik, David P. Fidler

Articles by Maurer Faculty

No abstract provided.

Developing Risk Assessment Maps For Schistosoma Haematobium In Kenya Based On Climate Grids And Remotely Sensed Data, Kelsey Lee Mcnally

LSU Master's Theses

It is important to be able to predict the potential spread of water borne diseases when building dams or redirecting rivers. This study was designed to test whether the use of a growing degree day (GDD) climate model and remotely sensed data (RS) within a geographic information system (GIS), could be used to predict both the distribution and severity of Schistosoma haematobium. Growing degree days are defined as the number of degrees centigrade over the minimum temperature required for development. The base temperature and the number of GDD required to complete one generation varies for each species. A monthly climate …

Evaluation And Implementation Of A Molecular-Based Protocol For The Identification Of Enteroviruses At The Florida Department Of Health – Tampa Laboratory, Matthew Adams Smith

USF Tampa Graduate Theses and Dissertations

The Enterovirus genus within the family Picornaviridae contains over 100 serotypes, of which sixty-four are known to be human pathogens. Infection with this group of RNA viruses produces a myriad of clinical conditions including poliomyelitis, meningitis, encephalitis, respiratory illnesses, and hand-foot-and-mouth disease. Outbreaks have been documented worldwide; significant morbidity and mortality exist to warrant laboratory surveillance.

Traditionally, enteroviruses have been identified to the level of serotype by the serum neutralization assay. However, numerous problems are associated with this assay. The serum neutralization assay is labor intensive, results are often ambiguous, and reagents are becoming difficult to obtain. Recently, molecular-based typing …

Is It 'Too Bloody Late'? : Older People's Attitudes To Physical Activity And To The Recommendations In The National Physical Activity Guidelines, Joan Jackson

Theses: Doctorates and Masters

Participation in physical activity confers many health benefits by reducing the risk factor for a number of lifestyle related diseases such as diabetes, colon cancer, and heart disease. Other benefits include improved mental and physical well-being. For older people the benefits are even more important; engagement in physical activity extends to such health benefits as reduction in the risk of falls and related potential injuries. However the most significant benefit to older people is that physical activity enables older people to live independently for longer and with a greater sense of well-being. This study explores, through qualitative research, older people's …

Occupational Hazards And Radiation Safety In Veterinary Practice Including Zoo Veterinary Practice In Australia, Joseph S. Jeyaretnam

Theses: Doctorates and Masters

This thesis contains reviews and research on the occupational hazards of zoo veterinary practitioners in Australia. Although occupational hazards have long been recognised in the veterinary profession, little information is available on the number and magnitude of injuries to veterinarians in Australia, the United Kingdom or the United States. Apart from anecdotal accounts and some limited data, most of the available information is on occupational zoonoses, generally well recognized by veterinarians. Other occupational hazards to which veterinarians are exposed have received scant attention. The veterinary practitioner in a zoo environment has to treat a range of captive wild species which …

Adolescent Participation In School Nutrition Meal Benefit Programs: A Case Study, Janice P. Maddox

Abraham S. Fischler College of Education ETD Archive

This applied dissertation is a historical case study targeted at the segment of a high school population who are eligible for free or reduced price meal benefits but do not take advantage of these benefits. The population to be studied is those students who take advantage of the free or reduced price benefits to which they are entitled less than 50% of the days that school is in session. Frequency of eating counts will be compared for the past 11 years in order to discern if the target population participation has changed over the years by programs designed to increase …