Digital Commons Network^™

A Domain Adaptation Approach For Segmenting Cell Instances In Microscopy Data, Matthew R. Keaton

Graduate Theses, Dissertations, and Problem Reports (ETD)

Automated cellular instance segmentation is a process that has been utilized for accelerating biological research since before the deep learning era, and recent advancements have produced higher quality results with less effort from the biologist. Most current endeavors focus on completely cutting the researcher out of the picture by generating highly generalized models. However, these models invariably fail when faced with novel data and effectively opt to miss out on the full capabilities of deep learning in pursuit of this goal. In our work, we demonstrate how, with even a minimal amount of annotated data, dominant approaches in this space …

Advanced Process Modeling And Optimization Of Amine-Based Carbon Capture Process, Paul Jide Terhemba Akula

Graduate Theses, Dissertations, and Problem Reports (ETD)

With the rise of carbondioxide (CO2) concentration in the atmosphere to more than 400 parts per million (ppm), research efforts have been focused on achieving net-zero carbon emission technologies. Post-combustion CO2 capture (PCC) is a key strategy in reducing CO2 emissions. Amine-based CO2 capture is the baseline technology for retrofitting existing power stations. However, the integration of amine-based PCC technology with power plants to reduce greenhouse gas emissions incurs a high energy penalty, decreasing a powerplant’s efficiency by about 23 percentage points. Understanding the capture plant dynamics plays an important role in its technical and economic performance. Rigorous models are …

Development Of An Innovative Co-Treatment Technology For Produced Water And Blowdown Water: A Regional Approach Of Water Management For Energy Production, Golnoosh Khajouei

Graduate Theses, Dissertations, and Problem Reports (ETD)

Freshwater use for power generation represents the second-largest water use globally. In the United States, freshwater withdrawals for thermoelectric power accounted for 38% of the total freshwater withdrawals for all uses in 2010. Cooling systems are the most water-intensive part of the thermoelectric generation process. For instance, one 300 MW power generator required about 20,000 m³/h circulating cooling water. The cooling operation discharges a large volume of wastewater in the form of blowdown water (10-20% of the consumed water) that requires treatment for reuse or surface discharge. Produced water (PW), the fluid which returns to the surface from …

Using Landsat-Based Phenology Metrics, Terrain Variables, And Machine Learning For Mapping And Probabilistic Prediction Of Forest Community Types In West Virginia, Faith M. Hartley

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigates the mapping of forest community types for the entire state of West Virginia, USA using Global Land Analysis and Discovery (GLAD) Phenology Metrics analysis ready data (ARD) derived from the Landsat time series and digital terrain variables derived from a digital terrain model (DTM). Both classifications and probabilistic predictions were made using random forest (RF) machine learning (ML) and training data derived from ground plots provided by the West Virginia Natural Heritage Program (WVNHP). The primary goal of this study is to explore the use of globally consistent ARD data for operational forest type mapping over a …

A Workflow For Unconventional Reservoirs Optimization Using Supervised Machine Learning In Conjunction With Orthorhombic Elasticity Modeling, Aymen Ab Ali Alhemdi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Due to the anisotropy and heterogeneous nature of unconventional reservoirs like shale, a comprehensive parametric study to optimize hydraulic fracture treatment for such reservoirs is a tough challenge, especially when natural fractures are present. Most of the current frac simulators do not consider the anisotropy of rock elasticity in the shales. Besides, using the fracture simulation linked with reservoir simulation for the parametric study to understand the impact of multiple different design parameters on fracture propagation and production is time expensive and low efficient. The study proposes a workflow including a new orthorhombic (OB) rock algorithm to interpret geomechanical properties …

Development Of An Entry-Scale Modeling Methodology To Provide Ground Reaction Curves For Longwall Gateroad Support Evaluation, Haochen Zhao

Graduate Theses, Dissertations, and Problem Reports (ETD)

Longwall gateroad entries are generally subjected to severe mining-induced stress changes and deformations; they are prone to large roof falls, floor heaves, and rib sloughing. The standing support system in underground mines needs to be carefully designed to compensate for the mining-induced deformation of the surrounding rock mass and consecutively protect the integrity of gateroad entries. Local geology, together with mining-induced stress redistribution, influences the ground response and plays a major role in the performance of a standing support design. In the US, Support Technology Optimization Program (STOP) and its Ground Reaction Curve (GRC) design criteria have been applied to …

Development And Verification Of Flight Data Informed Performance Estimation And Prediction Simulation Tool For Small Electrical Multi-Rotor Uav, Nicholas Scott Borelle

Graduate Theses, Dissertations, and Problem Reports (ETD)

While small scale multi-rotor aircraft are becoming an increasingly large market with applications emerging every day, their ability to have both a high endurance/long range and a high speed/performance flight is severely limited. This leads to uncertainty in mission planning and aircraft design, specifically when deciding mission length and available on-board energy. Uncertainty like this leads to an increased chance of failure to complete the mission, and a failure to recover the aircraft. Considering that these aircraft are used by everyone from hobbyists to commercial companies to military personnel, the applications and missions being flown carry importance and a serious …

Cytotoxic Effects Of Potential Irrigants For Endodontic Surgery, Kaiying Haggard

Graduate Theses, Dissertations, and Problem Reports (ETD)

Purpose: The aim of this study is to investigate if hypochlorous acid (Vashe and Endocyn), Ozone, sodium hypochlorite (0.5% NaOCl), chlorhexidine (0.12% CHX), and MTAD can be used as a disinfectant for endodontic surgery without causing bone tissue toxicity by comparing their cytotoxic effects to saline on osteoblasts in vitro.

Methods: Human Fetal Osteoblast Cells (hFOB 1.19, ATCC CRL-11372) were used. The cells viability after 10-minute exposure of Vashe, Endocyn, Ozone, NaOCl (0.5%), CHX (0.12%), MTAD, and saline at concentrations of 10, 30, 60, 90 % volume ratio were measured using CCK8 analysis and the absorbance were measured at 450 …

Microwave-Assisted Carbon Nanotube Growth From Methane On Surface Catalyst Exsolving Perovskite Oxide, Angela M. Deibel

Graduate Theses, Dissertations, and Problem Reports (ETD)

The novel method of using a perovskite exsolution catalyst, strontium titanium nickel oxide (STNO), proved capable of simultaneously producing carbon nanotubes (CNTs) and CO_x-free hydrogen during methane decomposition under microwave irradiation. An optimization of common perovskite materials was conducted for microwave-responsiveness with the results reported in this study. Out of the materials screened, strontium titanium nickel oxide (STNO) was the best candidate to achieve an acceptable methane conversion rate as well as a decent responsiveness to microwave. STNO was further optimized through Ni content, reduction dwell time, and reduction temperature to produce the best methane conversion and CNT …

A Combinatorial 5-Htr Expression Pattern Within The Ventral Projection Neurons Of The D. Melanogaster Olfactory Circuit., Mohd Freezely Ezzani Bin Mazri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neuromodulation allows neurons within a circuit to respond to stimuli from the environment according to the correct ecological value, context, and internal state of the animal. Serotonin (5-HT) is a neuromodulator that can generate different outcomes based on its target’s serotonin receptor (5-HTR) expression by affecting secondary messenger cascades. Within the Drosophila olfactory system, ventral projections neurons (vPN) express all five insect 5-HTR that project into two olfactory processing regions, the antennal lobe (AL) and the lateral horn (LH). The significance of this 5-HTR expression is unknown. In this study, I theorized the patterns of 5-HTR expression of vPNs. I …

Face Recognition With Attention Mechanisms, Qiangchang Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Face recognition has been widely used in people’s daily lives due to its contactless process and high accuracy. Existing works can be divided into two categories: global and local approaches. The mainstream global approaches usually extract features on whole faces. However, global faces tend to suffer from dramatic appearance changes under the scenarios of large pose variations, heavy occlusions, and so on. On the other hand, since some local patches may remain similar, they can play an important role in such scenarios. Existing local approaches mainly rely on cropping local patches around facial landmarks and then extracting corresponding local representations. …

An Examination Of Career Orientation Courses And College Students' Career Decision Self-Efficacy, Logan R. Mayhew

Graduate Theses, Dissertations, and Problem Reports (ETD)

Career development is an ongoing concern for college administrators as the modern knowledge era generates new and fluctuating jobs. College students are more anxious than in previous decades about starting their careers and making vocational decisions. Building career decision self-efficacy in students results in greater feelings of confidence and increases demonstration of career-related behaviors. Students in three online career courses at West Virginia University were assessed for gains in career decision self-efficacy in comparison with a control group after participation in the courses and compared on the basis of gender. Results of a mixed ANOVA indicated a significant increase in …

Development Of Capillary Vibrating Sharp-Edge Spray Ionization For Improving Continuous Flow Mass Spectrometry Analysis, Chong Li

Graduate Theses, Dissertations, and Problem Reports (ETD)

Capillary Vibrating Sharp-Edge Spray Ionization (cVSSI) is new ionization technique developed in the year of 2018. This ionization technique has attractive features such as simplicity, compactness, ease of manipulation, low costs, compatible with continuous flow, etc. However, the development of high performance cVSSI for mass spectrometry analysis is a process that needs unremitting optimizations. In this dissertation, I demonstrate the development of cVSSI for improving continuous flow mass spectrometry analysis. The chapter 2 focuses on improving the ionization efficiency of cVSSI through reducing the droplet size. Three strategies were tested to reduce the droplet size of VSSI. The most effective …

What Is The Perceived Self-Efficacy Of Defined Job Competencies For West Virginia University Extension Faculty?, Lacey Dawn Seckman

Graduate Theses, Dissertations, and Problem Reports (ETD)

The central mission of the Extension Service is to diffuse knowledge and resources developed by teaching and research experts at land grant universities to clientele within local communities (Cummings, et al., 2015; Hall & Broyles, 2016; Seevers & Graham, 2012). Making sure faculty are prepared to carry out their roles in all aspects to serve their clientele is key to quality Extension programs. Extension faculty can come from various backgrounds, interests, and expertise, all of which are influencers of self-efficacy. Having defined competencies for employees in Extension can help express what to expect in this job day-to-day. McClelland (1973) described …

Essays On Clean Water Act And Safe Drinking Water Act, Sharaban Tahura Anica

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation empirically examines three issues related to CWA and SDWA: 1) Financial Assistance and Environmental Compliance; 2) Financial Assistance Priorities from the Clean Water State Revolving Fund; and 3) Drinking Water Compliance during COVID-19 Pandemic.

Using the National Pollution Discharge Elimination System compliance and the Clean Water State Revolving Funds (CWSRF) data for wastewater treatment plants in nine states between 2010 and 2018, chapter 2 examines a) the effect of non-compliance on the distribution and size of awarded CWSRF loans, and b) the effects of the CWSRF provision and award size on post-funding compliance. Funded facilities are found to …

On The Classification Of Generalized Pseudo-Orthogonal Lie Groups Via Curvature, Cohomology, And Algebraic Structure, Adam C. Fletcher

Graduate Theses, Dissertations, and Problem Reports (ETD)

The study of Lie groups has yielded a rich catalogue of mathematical spaces that, in some sense, provide a theoretical and computational framework for describing the “world in which we live.” In particular, these topological groups that represent the rigid motions of a space, the behavior of subatomic particles, and the shape of the expanding universe consist of specialized matrices. In what follows, we define a new collection of matrices with a very specific transposition relation and attempt to classify this Lie group algebraically, geometrically, and topologically. We consider fields, $\Bbb{F},$ of characteristic zero and define the group of pseudo-orthogonal …

Synthetic Methods For Improved Scope And Efficiency Of Copper-Catalyzed Regioselective Alkene Boracarboxylation, Steven William Knowlden

Graduate Theses, Dissertations, and Problem Reports (ETD)

The synthesis of carboxylic acids is important to the chemistry community, owing to the broad applicability of these compounds as fine chemicals and pharmaceuticals. Method development over the last decade has focused on the preparation of carboxylic acids through transition metal catalysis utilizing CO₂ as a C1 synthon. Copper-catalyzed heteroelement(bora and sila)-carboxylation protocols provide functional group rich carboxylic acid products, yet remain underdeveloped and thus underutilized. Consequently, catalytic reductive difunctionalization methodologies in which CO₂ and B(pin) (pin = pinacolate: 2,3-dimethyl-2,3-butanediolate) are installed across the double bond of a vinyl arene were recently developed. These boracarboxylation protocols provided novel, …

Gan-Based Super-Resolution And Segmentation Of Retinal Layers In Optical Coherence Tomography Scans, Paria Jeihouni

Graduate Theses, Dissertations, and Problem Reports (ETD)

Optical Coherence Tomography (OCT) has been identified as a noninvasive and cost-effective imaging modality for identifying potential biomarkers for Alzheimer's diagnosis and progress detection. Current hypotheses indicate that retinal layer thickness, which can be assessed via OCT scans, is an efficient biomarker for identifying Alzheimer's disease. Due to factors such as speckle noise, a small target region, and unfavorable imaging conditions manual segmentation of retina layers is a challenging task. Therefore, as a reasonable first step, this study focuses on automatically segmenting retinal layers to separate them for subsequent investigations. Another important challenge commonly faced is the lack of clarity …

A Narrative Inquiry Into Veterans In Engineering, Miracle David Solley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Much research has been conducted on student veterans, in general; however, research on student veterans in engineering majors is very sparse. There is national recognition of the importance of student veterans in science, technology, engineering, and mathematics (STEM) fields as evidenced in the passage in 2020 of a bill investigating the lack of veteran students in these fields. This study adds to the literature by answering the following two research questions: What are the experiences of veteran engineering students? How has military service impacted those experiences? Twelve students and five professors from a Doctoral University: Very High Research Activity in …

Charge Dynamics Of Inas Quantum Dots Under Resonant And Above-Band Excitation, Gary R. Lander Jr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research involving light-matter interactions in semiconductor nanostructures has been an interesting topic of investigation for decades. Many systems have been studied for not only probing fundamental physics of the solid state, but also for direct development of technological advancements. Research regarding self-assembled, epitaxially grown quantum dots (QDs) has proven to be prominent in both regards. The development of a reliable, robust source for the production of quantum bits to be utilized in quantum information protocols is a leading venture in the world of condensed matter and solid-state physics. Fluorescence from resonantly driven QDs is a promising candidate for the production …

Integrated Large Discontinuity Factor, Lamodel And Stability Mapping Approach For Stone Mine Pillar Stability, Mustafa Baris Ates

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this research is to develop a software tool that integrates the large discontinuity factor (LDF) and the Boundary Element Method software (BEM), LaModel, to allow stone mine operators to assess the impact of the large discontinuities on local pillar stability. National Institute for Occupational Safety and Health (NIOSH) published design guidelines for underground stone mines to guide the industry in designing pillar and roof support. These guidelines emphasize the impact of large, angular discontinuities on pillar strength. Esterhuizen et al. (2011) derived the large discontinuity factor (LDF) to account for the impact of discontinuities on pillar stability …

Elucidating Biogeochemical Reactions Of Iron For Ammonium Removal And Nutrient Recovery From Wastewaters: Moving Toward Sustainable Wastewater Management, Rifat Anwar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Development and applications of anaerobic treatment technologies has been discussed as an effective alternative to conventional aerobic processes for removal of nitrogen from wastewaters. With abundance of iron and its high reduction potential, employing ferric reduction-based reaction pathways in engineering processes could be an effective strategy to promote energy efficiency of wastewater treatment. In particular, ferric reduction coupled to ammonium oxidation (Feammox), a novel microbial metabolic function recently found to occur under anaerobic/anoxic condition through iron dosing, can be used for nitrogen pollutant removal. Iron dosing for wastewater treatment could also promote other microbial and chemical reactions that facilitate nutrient …

The Process And Case Study Approach To Implementing A Nutrition-Specific Dissemination And Implementation Science Training In Appalachia, Ayron E. Walker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Nutrition professionals face implementation challenges due to their lack of knowledge to incorporate D&I science into intervention design. To improve intervention outcomes, nutrition professionals must be trained in D&I science, which are currently absent in the field.

Aims: To identify and assess nutrition educators and practitioners perceived motivations, self-efficacy, and attitudes in using D&I science to inform the educational design and strategies of a nutrition-specific D&I curriculum for nutrition educators. Then to test feasibility of the nutrition-specific curriculum in increasing knowledge, self-efficacy, and attitudes by a case study approach, pre/post intervention design.

Methods: First, scoping review methodology involved the …

Gun Culture 3.0, Andrew Phillip Stover

Graduate Theses, Dissertations, and Problem Reports (ETD)

There exist a criminology of firearms and an epidemiology of firearms use, but little in the way of a sociology of U.S. firearm ownership. Most social science study of firearms concerns illicit gun use and the harm that use produces. Compared to this body of work, little has been done to explore the culture of legal gun ownership. A few social scientists have attempted to change this by contributing their own interpretations of what a sociology of U.S. gun ownership might look like. Professor David Yamane, in doing just this, has posited a cultural model of contemporary gun ownership he …

Nano-, Encapsulated Manganese Oxide (Nemo) Particles For Mri Enhancement In Microfluidic Tumor Models, Kasey Alexis Freshwater

Graduate Theses, Dissertations, and Problem Reports (ETD)

Breast cancer is among the deadliest cancers in women, with approximately 2.3 million new cases and 685,000 deaths reported globally in 2020 alone. Magnetic Resonance Imaging (MRI) is commonly used to diagnose, stage, and develop treatment plans for patients predisposed to breast cancer. However, current MRI-based screening of breast cancer has high false-positive rates up to 25%, leading to unnecessary invasive follow-up screening and testing. The gold-standard intravenous gadolinium (Gd)-based contrast agents (GBCAs) account for false-positive rates because they are always “ON”, providing a constant MRI signal that highlights both benign and malignant tumors. The work detailed in this thesis …

“I Lost Everything I Owned… Now I’M Growing That Back”: Narratives Of Redemption After Meth Immersed Lives, Danielle M. Stoneberg

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is a lack of knowledge on how the process of desisting (i.e., maintaining abstinence) works for those leaving immersed drug lifestyles, leaving a need for a better understanding of the role and impact of identity in drug desistance. Through secondary analysis of interview data from a sample of 33 former methamphetamine manufacturers, this study examines the applicability of Maruna’s (2001) redemption narrative framework and identifies other aspects featured in their narratives that signaled identity change. Results found all participants discussed at least one component of the framework in their interviews. Their narrative identities changed over time to recognize that …

U.S.-Ukraine Relations And The Concept Of Strategic Partnership, Khrystyna Pelchar

Graduate Theses, Dissertations, and Problem Reports (ETD)

A strategic partnership has become particularly relevant in the wake of the Russian war in Ukraine. Most studies focus on the historical perspective of particular special relations leaning toward the long-standing nature and stability of those relations. Others describe interstate partnerships as dynamic developments rather than static phenomena. Conventionally, strategic partnerships are multifaceted, including the spheres of economic cooperation, military assistance and partnership, and democracy promotion. Scholars also single out cultural proximity as an important factor facilitating mutual trust and feasibility of strategic partnership.

This thesis will discuss the historical background of the U.S.-Ukraine economic, socio-political, and military cooperation and …

Human Welfare & Emergencies: Education, Natality, And Violence, Erika Antolin Davies

Graduate Theses, Dissertations, and Problem Reports (ETD)

I identify changes in human action during emergencies such as heavy precipitation and shelter-in-place orders. In two chapters I explore the effects of precipitation on educational attainment and birth rates as residential broadband access increases. In my third chapter I identify the movement of pets in and out of the home as a trigger for domestic violence during the COVID-19 lockdown. I estimate difference-in-difference regressions with panel data, coming to three conclusions. First: educational attainment in Appalachia is stunted by precipitation, as students have difficulty getting to school in bad weather. As this historically under-educated region of the US gains …

Expanding The Applicability Of Press-Brake-Formed Tub Girders Through The Extension Of The Maximum Span Length And The Evaluation Of Pier Continuity, Robert M. Tennant

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Short Span Steel Bridge Alliance (SSSBA) is a group of bridge and buried soil steel structure industry leaders who provide educational information on the design and construction of short-span steel bridges in installations up to 140 feet in length. Within the SSSBA technical working group, a modular, shallow press-brake-formed tub girder (PBFTG) was developed to address the demand in the short-span steel bridge market for rapid infrastructure replacement solutions. PBFTGs consist of modular, shallow, trapezoidal boxes fabricated from cold-bent structural steel plate. A concrete deck, or other deck option, may be placed on the girder, and the modular unit …

Top-Down & Bottom-Up Approaches To Robot Design, Dylan Michael Covell

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis presents a study of different engineering design methodologies and demonstrates their effectiveness and limitations in actual robot designs. Some of these methods were blended together with focus on providing an easily interpreted project design flow while implementing more bottom-up, or feedback, elements into the design methodology. Typically design methods are learned through experience, and design taught in academia aims to shape and formalize previous experience. Usually, inexperienced engineers are taught approaches resembling the Verein Deutscher Ingenieure (VDI) 2221 process. This method presented by the Association of German Engineers in 2006 is regarded as the general system design process. …