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Graduate Theses, Dissertations, and Problem Reports (ETD)

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Food Security And Coping Mechanisms In Kenya's Marginal Areas: The Case Of West Pokot., Anne Kisaka Nangulu Jan 2001

Food Security And Coping Mechanisms In Kenya's Marginal Areas: The Case Of West Pokot., Anne Kisaka Nangulu

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study analyzes food security and coping mechanisms in semi-arid West Pokot between 1920–1995. Based on a wide array of primary and secondary sources, the study analyzes the historical role of indigenous irrigation, specifically furrow irrigation, rain-fed farming and livestock keeping, in food production and food security among the Pokot of northwest Kenya. Besides farming and herding, the study also analyzes trade, hunting and gathering, as well as lending and borrowing (for example of food) based on reciprocity, and their contribution to food security in the area. In the colonial and post-colonial West Pokot, income from wage labor and mining …

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A Study Of The Relationship Between Characteristics Of Faculty Members In West Virginia Colleges And Their Level Of Implementation Of Information Technology., Andrew Neale Blackwood Jan 2001

A Study Of The Relationship Between Characteristics Of Faculty Members In West Virginia Colleges And Their Level Of Implementation Of Information Technology., Andrew Neale Blackwood

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined the relationships between characteristics of faculty members in West Virginia colleges and their level of information technology (IT) implementation. A one-shot case study research design was used to investigate the connection between the faculty members' gender, age, years of experience, academic discipline, rank, amount of computer education, computer access, Internet access, job satisfaction, and their level of IT implementation. The specially designed Computer Usage Survey was mailed to a randomly selected sample of 95 faculty members; responses were received from 64 (67%) faculty members. Data analysis identified statistically significant relationships between the faculty members' gender, years of …

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To Build, And Plant, And Keep A Table': Class, Gender, And The Ideology Of Improvement In Eighteenth-Century Women's Literature., Jeannie C. Dalporto Jan 2001

To Build, And Plant, And Keep A Table': Class, Gender, And The Ideology Of Improvement In Eighteenth-Century Women's Literature., Jeannie C. Dalporto

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this dissertation, I argue that the discourse of improvement, which stressed profit and productivity on the land and in the household, helped to define—and was defined by—class and gender ideology in the eighteenth century. I read the works of laboring class women poets, Mary Collier and Mary Leapor, and the utopian novelist, Sarah Scott, within the framework of land improvement treatises and household books. In doing so, I demonstrate how ideologies of labor and gender are inherently bound up with socioeconomic concerns about land and estate management. In Chapter one, I examine how notions of thrift found in land …

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The Presbyterian Church Of East Africa: An Account Of Its Gospel Missionary Society Origins, 1895-1946., Evanson Ndungu Wamagatta Jan 2001

The Presbyterian Church Of East Africa: An Account Of Its Gospel Missionary Society Origins, 1895-1946., Evanson Ndungu Wamagatta

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation traces the Gospel Missionary Society origins of the Presbyterian Church of East Africa (PCEA). The church was established when the Gospel missionary Society (GMS) from the United States of America (USA) and the Church of Scotland Mission (CSM) from Scotland merged their work in 1946. Consequently, the focus of this study is the work of the GMS in Kenya from when it was inaugurated in 1895 to the time of the merger in 1946. As shown in this dissertation, the GMS initially had no intention of establishing its work and then hand it over to the CSM as …

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Mechanisms Of Chromium(Vi)-Induced Carcinogenesis: The Involvement Of Reactive Oxygen Species And Signal Transduction Pathway., Suwei Wang Jan 2001

Mechanisms Of Chromium(Vi)-Induced Carcinogenesis: The Involvement Of Reactive Oxygen Species And Signal Transduction Pathway., Suwei Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Although Cr(VI)-containing compounds have been widely recognized as carcinogens for over 100 years, the mechanisms of their actions are not fully understood. The overall objective of this study is to investigate the role of reactive oxygen species (ROS) in Cr(VI)-induced carcinogenesis, focusing on tumor suppressor protein p53 and regulatory signal transduction pathways. In the present study, the role of ROS in p53 activation was investigated and the following conclusions were obtained: (a) Cr(VI) is able to activate p53 protein; (b) ROS, especially ·OH radical, are responsible for the p53 activation induced by Cr(VI). In addition, we presented a mechanism of …

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The Role Of Accessory Proteins In Controlling The Thyroid Hormone Regulation Of Transcription Of The Malic Enzyme Gene., Yutong Wang Jan 2001

The Role Of Accessory Proteins In Controlling The Thyroid Hormone Regulation Of Transcription Of The Malic Enzyme Gene., Yutong Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Triiodothyronine (T3) stimulates a 70-fold or greater increase in transcription of the malic enzyme gene in chick embryo hepatocytes. Previous work has shown that the effects of T3 on malic enzyme transcription are mediated in large part by sequence elements located within a liver-specific and T3-inducible DNase I hypersensitive region in the 5′-flanking DNA of the malic enzyme gene. Within this DNase I hypersensitive region is a cluster of nuclear T3 receptor (TR) binding sites that together constitute a T3 response unit (TAU). Flanking the T3RU are accessory elements that enhance T3 regulation conferred by the T3RU in chick embryo …

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An Investigation Of Teachers' Temperament And Students' Perceptions Of Teachers: Communication Behavior And Students' Attitudes Toward Teachers., Kristin Marie Valencic Jan 2001

An Investigation Of Teachers' Temperament And Students' Perceptions Of Teachers: Communication Behavior And Students' Attitudes Toward Teachers., Kristin Marie Valencic

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined relationships among the way teachers communicate in the classroom, teachers temperaments, and perceptions of teachers by students. Specifically, the first goal was to determine to what extent a teacher's levels of extraversion, neuroticism, and psychoticism can predict students perceptions of task attraction, immediacy, assertiveness, responsiveness, and credibility. The second goal was to determine the relationships between teacher temperament and teacher evaluations, affective learning, and cognitive learning. Self-report surveys of 52 teachers and 1242 students across seven disciplines at West Virginia University were collected. Instructors received measures of extraversion, neuroticism, and psychoticism. Teachers were asked to rate themselves …

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Psychophysiological Responses Of Older Adults To An Anxiety -Evoking Stimulus, Angela W. Lau Dec 2000

Psychophysiological Responses Of Older Adults To An Anxiety -Evoking Stimulus, Angela W. Lau

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to clarify the relation between anxiety and physiological responses in older adults as compared to younger adults. Heart rate (HR), skin conductance level (SCL), skin conductance response (SCR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were obtained before, during, and after exposure to a Stroop color-word naming task and a snake video from 46 female younger adults (age 18--30) and 28 female older adults (age 65--80) who were designated as either snake fearful or snake nonfearful. No significant group differences were observed on physiological measures to baseline one or during the snake …

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Hazardous Materials Database, Veena Vadiala Dec 2000

Hazardous Materials Database, Veena Vadiala

Graduate Theses, Dissertations, and Problem Reports (ETD)

Handling and disposal of a retired object can be a major component of its Life Cycle Cost. Often, during dismantling of a retired object many hazardous materials are released. Disposal of hazardous materials also need to comply with various federal regulations. Agencies like Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA) set these safety regulations. It is possible to apply generic exposure and release controls to protect workers from hazardous materials. For the most cost effective hazard controls it is necessary first to identify the materials and their properties of primary concern. There is a need …

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Essential Oil Treatments To Control Varroa Destructor Anderson And Trueman 2000 (Formerly Varroa Jacobsoni Oudemans 1904) (Mesostigmata: Varroidae), Maria Mercedes Vargas-Sarmiento Dec 2000

Essential Oil Treatments To Control Varroa Destructor Anderson And Trueman 2000 (Formerly Varroa Jacobsoni Oudemans 1904) (Mesostigmata: Varroidae), Maria Mercedes Vargas-Sarmiento

Graduate Theses, Dissertations, and Problem Reports (ETD)

Varroa destructor Anderson and Trueman is the most serious pest of the honey bee Apis mellifera L. Varroa mites transmit several viruses, bacteria and fungi to the bees, which results in a condition called parasitic mite syndrome. There are no completely reliable treatments available to control the mite. Fifty-one beehives were artificially infested with varroa mites by using three different methods. Observations on mite population growth during three infestation attempts were made. All colonies were inspected for the presence of the small hive beetle, Aethina tumida Murray, no beetles were found. Thirty-five colonies were used to establish the efficacy of …

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Design, Construction, And Evaluation Of Coal Extraction Pilot Plant To Manufacture Coal-Based Carbon Pitch, Brian Wayne Bland Dec 2000

Design, Construction, And Evaluation Of Coal Extraction Pilot Plant To Manufacture Coal-Based Carbon Pitch, Brian Wayne Bland

Graduate Theses, Dissertations, and Problem Reports (ETD)

A solvent extraction technique for removing mineral matter, including the inorganic sulfur, from coal has been developed by the Department of Chemical Engineering at WVU. The extraction is preformed at mild conditions (202°C and atmospheric pressure) using the solvent N-Methyl-2-Pyrrolidone (NMP). Laboratory results have shown that this technique yields a clean coal product containing less than 1 percent ash and virtually no inorganic sulfur.;This research was conducted for further process design and economic development of an industrial-scale extraction process.;This research reported the possibility of production scale processing by constructing a pilot plant. The pilot plant was used to explore the …

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Representative Ways To Analyze And Survey Changes In Long-Term Electrocardiographic Recordings, Simona Gabriela Crihalmeanu Dec 2000

Representative Ways To Analyze And Survey Changes In Long-Term Electrocardiographic Recordings, Simona Gabriela Crihalmeanu

Graduate Theses, Dissertations, and Problem Reports (ETD)

The goal of this research is to explore techniques with which long-term physiologic time-series data can be analyzed, so that relevant changes in physiological signals, particularly the electrocardiogram signal, can be captured, processed, quantified and stored. A new experimental model was developed such that the electrocardiogram can be monitored continuously over thirteen weeks. Cardiotoxicity was progressively induced with doxorubicin in a rabbit model, and electrocardiographic progressions from normal state to diseased state were continuously tracked. Automated methods for analyzing the data were developed to manage and control the extensive electrocardiogram dataset. A significant challenge to this work is the sheer …

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Effects Of Ownership And Circulation On Editorial Presentation In West Virginia Newspapers, Matthew E. Umstead Dec 2000

Effects Of Ownership And Circulation On Editorial Presentation In West Virginia Newspapers, Matthew E. Umstead

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis, which focuses on the post-yellow journalism era in West Virginia, further develops the body of research done on the influence of chain ownership in newspapers.;Historically, strong political biases in news coverage were found in the yellow journalism, early 20th century period. And this study finds a conservative bias on the opinion-editorial pages in a traditionally Democratic state with few competing media markets and reliance upon newspapers for local news. This thesis finds ownership status and circulation size affects the balance and variety of feature items presented within the opinion editorial content. Thus, previous research suggesting chain ownership influence …

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Limits Of Sensitivity To Delayed Timeout From Avoidance, Chad Michael Galuska Dec 2000

Limits Of Sensitivity To Delayed Timeout From Avoidance, Chad Michael Galuska

Graduate Theses, Dissertations, and Problem Reports (ETD)

Session-reduction procedures have been employed to assess molar control of avoidance responding. By conceptualizing session reduction as a delayed timeout from avoidance, the present study investigated the limits of molar control while minimizing several methodological limitations inherent in such procedures. Six times during each session, a two-link chain schedule was superimposed on a baseline schedule of variable-cycle shock avoidance. Completion of the initial link (fixed-ratio 10 schedule) produced a timeout following a signaled delay during which the avoidance schedule remained operative. For most rats, the delay was manipulated across conditions from 0 s to 60 s. Control by the delayed …

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Persistence Of Response Variation And Repetition, Adam Howard Doughty Dec 2000

Persistence Of Response Variation And Repetition, Adam Howard Doughty

Graduate Theses, Dissertations, and Problem Reports (ETD)

A multiple chained schedule was used to assess the persistence of fixed and variable response sequences. In one terminal link, a single 4-peck response sequence produced food (Repeat) and in the other terminal link a 4-peck response sequence produced food only if it had been occurring infrequently relative to the other 15 possible responses (Vary). Similar response and reinforcement rates occurred in each terminal link. Identical variable-interval 20-s schedules operated in the initial links preceding each terminal link and lower response rates reliably occurred in the initial link preceding the Vary terminal link. After responding stabilized under the multiple chained …

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Commercialism, Subsistence, And Competency On The Western Virginia Frontier, 1765--1800, John M. Boback Dec 2000

Commercialism, Subsistence, And Competency On The Western Virginia Frontier, 1765--1800, John M. Boback

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since the early nineteenth century, Americans have frequently associated the pioneers of the Appalachian Mountains with subsistence farming, economic independence, and a certain degree of hostility toward capitalism. This thesis disproves the myth of pioneer self-sufficiency by demonstrating how the men and women who settled in western Virginia during the final third of the eighteenth century used a variety of tactics in their struggle to achieve a competency. Although subsistence activities, such as hunting and farming, undoubtedly held an important place in the backcountry domestic economy, the settlers also interacted with the commercial market as both producers and consumers of …

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Effects Of Gender And Gender Role On Cardiovascular Reactivity And Anger Experience During An Interpersonal Interaction, Andria Leigh Black Dec 2000

Effects Of Gender And Gender Role On Cardiovascular Reactivity And Anger Experience During An Interpersonal Interaction, Andria Leigh Black

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined gender and gender role differences in cardiovascular reactivity and anger experience during an interpersonal interaction. Ninety-six participants interacted in dyads (traditional masculine men with traditional feminine women, and androgynous men with androgynous women). Agency (degree of challenge; High versus Low) and Communion (degree of agreement; Agree versus Disagree) were manipulated. Heart rate (HR) and systolic and diastolic blood pressure (SBP and DBP) were assessed. Participants completed questionnaires assessing state and trait anger, and angry thoughts. Traditional women exhibited higher HR during speaking and listening intervals than other groups. Higher levels of state anger were reported for individuals …

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Evaluation Of Survival And Recovery Characteristics Of Bifidobacteria As Indicators Of Fecal Pollution Of Water, John Elmer Ravenscroft Jr. Dec 2000

Evaluation Of Survival And Recovery Characteristics Of Bifidobacteria As Indicators Of Fecal Pollution Of Water, John Elmer Ravenscroft Jr.

Graduate Theses, Dissertations, and Problem Reports (ETD)

The examination of aquatic environments for bacterial indicator organisms has proven to be a useful and well-established practice for the purpose of monitoring microbiological water quality. An ideal indicator of fecal pollution should be present in sufficient density to allow detection, present simultaneous with pathogen(s), incapable of aftergrowth in external aquatic environments, easy to enumerate, and exclusively of fecal origin. Unfortunately, none of the indicator organisms presently in use today meet all of these requirements. Bifidobacteria show promise as indicators of fecal pollution in water with the additional ability of potentially distinguishing between fecal pollution of human and animal origin. …

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Encoding Of Periodic Skin Stimuli By Spinal Dorsal Horn Neurons, Jeffrey J. Lawson Dec 2000

Encoding Of Periodic Skin Stimuli By Spinal Dorsal Horn Neurons, Jeffrey J. Lawson

Graduate Theses, Dissertations, and Problem Reports (ETD)

The encoding of vibrotactile pitch by neurons of the somatosensory system has been investigated at many levels of the neuraxis. These studies, however, have not extended to the spinal dorsal horn, which is known to process low threshold mechanoreceptive input. The studies presented here were designed to assess the possible role of the dorsal horn in the encoding of vibrotactile pitch. To accomplish this task, dorsal horn single unit extracellular recordings were obtained during periodic electrical and sinusoidal mechanical stimulation of their receptive fields. Techniques used in classifying vibrotactile pitch encoding were similar to those used in other somatosensory nuclei, …

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Alexander Von Humboldt And Nineteenth-Century Ideas On The Origin Of American Indians, Michael Anthony Wadyko Dec 2000

Alexander Von Humboldt And Nineteenth-Century Ideas On The Origin Of American Indians, Michael Anthony Wadyko

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation revolves around Alexander von Humboldt's research on Indian origins. Humboldt conducted investigations on Indians during his precedent-setting scientific expedition to Meso- and South America during the years 1799--1804. Officially sponsored by the Spanish crown, the main purposes for this expedition were twofold: to examine, evaluate, and discredit Buffon's "degeneracy" claims about America and its inhabitants, and to gather empirical evidence on geography, climate, flora, fauna, and the indigenous cultures. From these results Humboldt published three major works about the expedition, particularly a thirty-volume work condensed to two volumes, Vues de Cordilleres et monuments des peuples d' Amerique.;From this …

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Characterization Of The Airway Epithelial Bioelectric Mechanisms Associated With The Effects Of Epithelium-Derived Relaxing Factor In Guinea Pig-Isolated Trachea, Richard Alan Johnston Dec 2000

Characterization Of The Airway Epithelial Bioelectric Mechanisms Associated With The Effects Of Epithelium-Derived Relaxing Factor In Guinea Pig-Isolated Trachea, Richard Alan Johnston

Graduate Theses, Dissertations, and Problem Reports (ETD)

In response to elevated serosal or mucosal tonicity, guinea-pig tracheal epithelium releases the non-nitric oxide, non-prostanoid, epithelium-derived relaxing factor (EpDRF), which subsequently diffuses to the underlying airway smooth muscle to initiate relaxation. Hypertonicity-induced smooth muscle relaxation via EpDRF involves epithelial Na+ and Cl- channels and is preceded by a depolarization of the transepithelial potential difference (Vms). By utilizing two different experimental systems, this study sought to characterize further the airway epithelial bioelectric mechanisms associated with the effects of EpDRF in guinea-pig isolated trachea.;First, this study attempted to elucidate which epithelial ion channels and/or transporters are involved in the depolarization of …

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Finite Element Modeling Of Dowel -Jointed Plain Concrete Pavement Response To Thermal And Moving Traffic Loads, Michel Ramsis Fahmy Dec 2000

Finite Element Modeling Of Dowel -Jointed Plain Concrete Pavement Response To Thermal And Moving Traffic Loads, Michel Ramsis Fahmy

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this study was to develop Three Dimensional Finite Element Models (3D-FEM) that can be used to investigate the separate or combined effect of moving axle loads and thermal gradient on the response of dowel Jointed Portland Cement Concrete Pavement (JPCCP) structures. The availability of a mechanistic tool that can be used for an accurate prediction of rigid pavement response to such loads would enable designing longer lasting pavements and understanding some of its modes of distress. In this respect, finite element modeling offers a powerful tool for the simulation of the structural behavior of pavements under the …

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Parallelization Of Ecg Template-Based Abnormality Detection, Sherry Lea Kratsas Dec 2000

Parallelization Of Ecg Template-Based Abnormality Detection, Sherry Lea Kratsas

Graduate Theses, Dissertations, and Problem Reports (ETD)

In order to develop techniques to predict cardiac arrest, long-term study of electrocardiogram (ECG) data needs to be done to detect changes in electrical activity of diseased hearts. In the past, limitations of computing power and storage space restricted the duration of long-term studies to several days. However, with today's technological advancement, data collection can be extended to months or years. The goal of this thesis research is to evaluate several alternatives for distributing the analysis of ECG data over multiple processors. Parallel algorithms utilizing Correlation Waveform Analysis (CWA) were implemented to compare individual heartbeats and form heartbeat templates. The …

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West Virginians' Perceptions And Use Of Complementary Medicine, Joshua David Blevins Dec 2000

West Virginians' Perceptions And Use Of Complementary Medicine, Joshua David Blevins

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to determine how West Virginian's perceive and use complementary medicine. The first objective was to determine the frequency of respondents who had used at least one complementary therapy in the last year. The second objective was to determine the most commonly used complementary therapies among respondents. The third objective was to examine the demographic characteristics of respondents who used complementary therapies. The fourth objective was to determine if certain types of medical problems led to complementary medicine use among respondents. The fifth objective was to show the percentage of users who informed their physician …

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Evidence For A Systemic Embryotoxic Effect Of Early Luteal Regression In The Ewe, Beth Alyson Costine Dec 2000

Evidence For A Systemic Embryotoxic Effect Of Early Luteal Regression In The Ewe, Beth Alyson Costine

Graduate Theses, Dissertations, and Problem Reports (ETD)

Experiments were performed to determine if a short-lived corpus luteum was embryotoxic in ewes given supplemental progesterone and the route of transfer of embryotoxic products. Mated ewes were lutectomized or sham lutectomized on day 4 after estrus. Following surgery, ewes received saline or PGF 2alpha through days 6 or 7. Pregnancy rate was reduced after treatment with PGF2alpha (P < 0.001) compared to controls and was increased in PGF2alpha-treated ewes by lutectomy (P < 0.05). Mated ewes with bilateral ovulations were unilaterally lutectomized, and each uterine horn was ligated to eliminate intercornual flow on day 4 after estrus. Treatment with PGF2alpha on day 5 through 8 reduced pregnancy rates (P < 0.01), but embryonic survival did not differ in the uterine horns ipsilateral or contralateral to the regressing CL. The regressing CL is embryotoxic in progesterone-supplemented ewes, and embryotoxic luteal products have been shown to act by non-local pathways.

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Agricultural Non-Point Source (Agnps) Water Quality Modeling In A Gis Environment, Stephen George Carpenter Aug 2000

Agricultural Non-Point Source (Agnps) Water Quality Modeling In A Gis Environment, Stephen George Carpenter

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis project outlines the development and implementation of a complex GIS project in a government agency. The objective of the project was to integrate a public domain GIS package (GRASS) with a commercial structured query language database in order to undertake Agricultural Non-Point Source (AGNPS) water quality modeling. Three general areas of GIS technology were investigated consisting of technical issues involved in linking GIS; the model; database development; and a discussion of system performance from an institutional perspective.

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Assessing West Virginia Nipf Owner Characteristics And Preferred Assistance Topics, Daniel Joseph Magill Aug 2000

Assessing West Virginia Nipf Owner Characteristics And Preferred Assistance Topics, Daniel Joseph Magill

Graduate Theses, Dissertations, and Problem Reports (ETD)

Four hundred and fifty-one Non-Industrial-Private-Forest (NIPF) owners (49% response rate) in West Virginia responded to a survey of their forestry assistance needs. Most of the socioeconomic characteristics of the respondents, their reasons for owning the property, the types of activities they were engaged in on the property and the agencies that provided assistance by themselves significantly (Chi2 & ANOVA) differentiated those interested and not interested in obtaining assistance. However, when all 39 factors were considered together (Logistic Regression) only a small number of these factors were needed to explain the difference between landowners wanting and not wanting a specific assistance …

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Effects Of Acetaminophen On Estrogen-Responsive Alkaline Phosphatase In Ishikawa Endometrial Cancer Cells, Janet A. Dowdy Aug 2000

Effects Of Acetaminophen On Estrogen-Responsive Alkaline Phosphatase In Ishikawa Endometrial Cancer Cells, Janet A. Dowdy

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the effect of acetaminophen (APAP) on the estrogen-responsive gene alkaline phosphatase in Ishikawa endometrial cancer cells. Basal levels of alkaline phosphatase activity were significantly inhibited in cells treated with 0.03, 0.1, 0.3 and 1mM APAP compared to control. Alkaline phosphatase activity induced with 1nM estradiol was significantly inhibited in a concentration dependent manner by 0.0.1, 0.3 and 1mM APAP. APAP did not directly inhibit the activity of alkaline phosphatase at any of the concentrations tested. Increasing estradiol concentrations (0.01, 0.1 and 1nM) did not alter the level of inhibition of alkaline phosphatase activity by 0.1, 0.3 or …

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Induction Of Myosin Cross-Reactive Antibody And Cytolytic T Cell Responses In Mice With Streptococcus Pyogenes, Cynthia Ann Cunningham Aug 2000

Induction Of Myosin Cross-Reactive Antibody And Cytolytic T Cell Responses In Mice With Streptococcus Pyogenes, Cynthia Ann Cunningham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impetigo and pharyngitis are two common suppurative infections in man elicited by Streptococcus pyogenes that lead to autoimmune complications in susceptible individuals. Although the underlying mechanisms for the onset of post-streptococcal autoimmunity have yet to be established, experimental information gained thus far suggests that the resultant pathology is a consequence of immunological cross-reactivity between streptococcal antigens, namely the anti-phagocytic factor M protein and host proteins, specifically myosin. Experimental animal model systems developed to date have predominantly relied on the immunization of adult animals with M protein emulsed in adjuvant. In the laboratory we have undertaken studies with mice to examine …

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Carnivalized Narratives In The Postmodern Long Poem, Joe Wade Moffett Aug 2000

Carnivalized Narratives In The Postmodern Long Poem, Joe Wade Moffett

Graduate Theses, Dissertations, and Problem Reports (ETD)

As a decidedly American tradition, the long poem has become the premier literary endeavor for poets in the twentieth-century. Writers such as T. S. Eliot, Ezra Pound, and William Carlos Williams have pursued the long poem, but under the auspices of the "modern epic." Three postmodern long poems---Kenneth Koch's Seasons on Earth, Edward Dom's Gunslinger, and James Merrill's The Changing Light at Sandover---illustrate a dramatic rupture with the texts of modernism by introducing comic situations and multi-voiced narration---situations described by Mikhail Bakhtin as "dialogism" and "carnival," receptively---into the canon of American long poems. These innovations allow the postmodern long poem …

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