Increased Dendrite Branching In Aβpp/Ps1 Mice And Elongation Of Dendrite Arbors By Fasudil Administration, 2010 University of Nebraska - Lincoln
Increased Dendrite Branching In Aβpp/Ps1 Mice And Elongation Of Dendrite Arbors By Fasudil Administration, Brian A. Couch, George J. Demarco, Shannon L. Gourley, Anthony J. Koleske
School of Biological Sciences: Faculty Publications
Amyloid-β (Aβ) overproduction and dendrite arbor atrophy are hallmarks of Alzheimer’s disease. The RhoA GTPase (Rho) signals through Rho kinase (ROCK) to control cytoskeletal dynamics and regulate neuron structure. Hyperactive Rho signaling destabilizes neurons leading to dendritic regression that can be rescued by genetic or pharmacological reduction of ROCK signaling. To understand what effect reduced ROCK signaling has on the dendrite arbors of mice that overproduce Aβ, we administered the ROCK inhibitor fasudil to AβPP/PS1 transgenic mice. We report that increased dendrite branching occurs in AβPP/PS1 mice and that fasudil promotes …
Mitochondrial-Nuclear Epistasis Affects Fitness Within Species But Does Not Contribute To Fixed Incompatibilities Between Species Of Drosophila, 2010 Indiana University
Mitochondrial-Nuclear Epistasis Affects Fitness Within Species But Does Not Contribute To Fixed Incompatibilities Between Species Of Drosophila, Kristi L. Montooth, Colin D. Meiklejohn, Dawn N. Abt, David M. Rand
School of Biological Sciences: Faculty Publications
Efficient mitochondrial function requires physical interactions between the proteins encoded by the mitochondrial and nuclear genomes. Co-evolution between these genomes may result in the accumulation of incompatibilities between divergent lineages. We test whether mitochondrialnuclear incompatibilities have accumulated within the Drosophila melanogaster species subgroup by combining divergent mitochondrial and nuclear lineages and quantifying the effects on relative fitness. Precise placement of nine mtDNAs from D. melanogaster, D. simulans and D. mauritiana into two D. melanogaster nuclear genetic backgrounds reveals significant mitochondrial-nuclear epistasis affecting fitness in females. Combining the mitochondrial genomes with three different D. melanogaster X chromosomes reveals significant epistasis …
Compositions And Methods For Controlling Plant Parasitic Nematodes, 2010 Kansas
Compositions And Methods For Controlling Plant Parasitic Nematodes, Harold N. Trick, Judith L. Roe, Timothy C. Todd, Michael A. Herman
School of Biological Sciences: Faculty Publications
The present invention relates to compositions and methods for controlling nematode infestation of plants. In particular, the present invention provides vectors comprising sequences designed to control nematodes by RNA interference (RNAi) and transgenic plants transformed with Such vectors.
Integrating Spatial And Temporal Approaches To Understanding Species Richness, 2010 Utah State University
Integrating Spatial And Temporal Approaches To Understanding Species Richness, Ethan P. White, S. K. Morgan Ernest, Peter B. Adler, Allen H. Hurlbert, S. Kathleen Lyons
School of Biological Sciences: Faculty Publications
Understanding species richness patterns represents one of the most fundamental problems in ecology. Most research in this area has focused on spatial gradients of species richness, with a smaller area of emphasis dedicated to understanding the temporal dynamics of richness. However, few attempts have been made to understand the linkages between the spatial and temporal patterns related to richness. Here, we argue that spatial and temporal richness patterns and the processes that drive them are inherently linked, and that our understanding of richness will be substantially improved by considering them simultaneously. The species–time–area relationship provides a case in point: successful …
Factors Affecting The Spatial Distribution Of Black Mangrove On The Dredged-Material Or “Spoil” Islands In The Lower Laguna Madre Of Texas, 2010 The University of Texas Rio Grande Valley
Factors Affecting The Spatial Distribution Of Black Mangrove On The Dredged-Material Or “Spoil” Islands In The Lower Laguna Madre Of Texas, Violet Yeager, Kenneth R. Summy, Frank W. Judd, Robert I. Lonard, Ruben A. Mazariegos, James H. Everitt, Michael R. Heep, Thomas Whelan
Biology Faculty Publications and Presentations
Research was conducted to evaluate the spatial distribution of black mangrove (Avicennia germinans) on the dredged-material or “spoil” islands of the Lower Laguna Madre of Texas. Aerial color-infrared (CIR) photographs revealed the presence of black mangrove stands on many of the islands located south of the Arroyo Colorado (a distributary of the Rio Grande which empties into the Laguna Madre), but failed to detect significant mangrove stands on islands located north of the Arroyo. Analysis of CIR photographs and supervised image classifications for individual islands suggested a concentration of black mangrove along western shorelines and relatively low interior areas of …
Improved Detection Of Bartonella Dna In Mammalian Hosts And Arthropod Vectors By Real-Time Pcr Using The Nadh Dehydrogenase Gamma Subunit (Nuog), 2010 Loyola University Chicago
Improved Detection Of Bartonella Dna In Mammalian Hosts And Arthropod Vectors By Real-Time Pcr Using The Nadh Dehydrogenase Gamma Subunit (Nuog), James M. Colborn, Michael Y. Kosoy, Vladimir L. Motin, Maxim V. Telepnev, Gustavo Valbuena, Khin S. Myint, Yuri Fofanov, Catherine Putonti, Chen Feng, Leonard Peruski
Bioinformatics Faculty Publications
We used a whole-genome scanning technique to identify the NADH dehydrogenase gamma subunit (nuoG) primer set that is sensitive and specific enough to detect a diverse number of Bartonella species in a wide range of environmental samples yet maintains minimal cross-reactivity to mammalian host and arthropod vector organisms.
Adaptive Evolution And Inherent Tolerance To Extreme Thermal Environments, 2010 Loyola University Chicago
Adaptive Evolution And Inherent Tolerance To Extreme Thermal Environments, Jennifer Cox, Alyxandria Schubert, Michael Travisano, Catherine Putonti
Bioinformatics Faculty Publications
Background
When introduced to novel environments, the ability for a species to survive and rapidly proliferate corresponds with its adaptive potential. Of the many factors that can yield an environment inhospitable to foreign species, phenotypic response to variation in the thermal climate has been observed within a wide variety of species. Experimental evolution studies using bacteriophage model systems have been able to elucidate mutations, which may correspond with the ability of phage to survive modest increases/decreases in the temperature of their environment.
Results
Phage ΦX174 was subjected to both elevated (50°C) and extreme (70°C+) temperatures for anywhere from a few …
Mechanisms Responsible For A Φx174 Mutant's Ability To Infect Escherichia Coli By Phosphorylation, 2010 Loyola University Chicago
Mechanisms Responsible For A Φx174 Mutant's Ability To Infect Escherichia Coli By Phosphorylation, Jennifer Cox, Catherine Putonti
Bioinformatics Faculty Publications
The ability for a virus to expand its host range is dependent upon a successful mode of viral entry. As such, the host range of the well-studied ΦX174 bacteriophage is dictated by the presence of a particular lipopolysaccharide (LPS) on the bacterial surface. The mutant ΦX174 strain JACS-K, unlike its ancestor, is capable of infecting both its native host Escherichia coli C and E. coli K-12, which does not have the necessary LPS. The conversion of an alanine to a very reactive threonine on its virion surface was found to be responsible for the strain's expanded host range.
Using Geographically Structured Evaluations To Assess Performance And Transferability Of Ecological Niche Models For Species With Many Occurrence Records: A Test Using The Caribbean Spiny Pocket Mouse, Heteromys Anomalus, 2010 CUNY City College of New York
Using Geographically Structured Evaluations To Assess Performance And Transferability Of Ecological Niche Models For Species With Many Occurrence Records: A Test Using The Caribbean Spiny Pocket Mouse, Heteromys Anomalus, Aleksandarc Radosavljevi
Dissertations and Theses
No abstract provided.
Garden Of The Gods At Colorado Springs: Paleozoic And Mesozoic Sedimentation And Tectonics, 2010 Liberty University
Garden Of The Gods At Colorado Springs: Paleozoic And Mesozoic Sedimentation And Tectonics, Marcus R. Ross, William A. Hoesch, Steven A. Austin, John H. Whitmore, Timothy L. Clarey
Faculty Publications and Presentations
Exposed along the southeast fl ank of the Colorado Front Range are rocks that beautifully illustrate the interplay of sedimentation and tectonics. Two major rangebounding faults, the Ute Pass fault and the Rampart Range fault, converge on the Garden of the Gods region west of Colorado Springs. Cambrian through Cretaceous strata upturned by these faults reveal in their grain compositions, textures, and bedforms radically different styles of sedimentation. The Cambrian/Ordovician marine transgressive deposits appear to have come to rest on a passive and tectonically inactive craton. In contrast, coarse-grained Pennsylvanian/Permian marine deposits of the Fountain Formation and Lyons Sandstone reveal …
Apparent Competition With An Invasive Plant Hastens The Extinction Of An Endangered Lupine, 2010 University of California - Berkeley
Apparent Competition With An Invasive Plant Hastens The Extinction Of An Endangered Lupine, Emily M. Dangremond, Eleanor A. Pardini, Tiffany M. Knight
Biology Faculty Publications & Presentations
Invasive plants may compete with native plants by increasing the pressure of native consumers, a mechanism known as "apparent competition." Apparent competition can be as strong as or stronger than direct competition, but the role of apparent competition has rarely been examined in biological invasions. We used four years of demographic data and seed-removal experiments to determine if introduced grasses caused elevated levels of seed consumption on native plant species in a coastal dune system in California, USA. We show that the endangered, coastal dune plant Lupinus tidestromii experiences high levels of pre-dispersal seed consumption by the native rodent Peromyscus …
Seed Dispersal By Pulp Consumers, Not ‘‘Legitimate’’ Seed Dispersers, Increases Guettarda Viburnoides Population Growth, 2010 University of Missouri - St Louis
Seed Dispersal By Pulp Consumers, Not ‘‘Legitimate’’ Seed Dispersers, Increases Guettarda Viburnoides Population Growth, Andrea P. Loayza, Tiffany M. Knight
Biology Faculty Publications & Presentations
We examined the effect of seed dispersal by Purplish Jays (Cyanocorax cyanomelas; pulp consumers) and the Chestnut-eared Araçari (Pteroglossus castanotis; "legitimate" seed dispersers) on population growth of the small tree Guettarda viburnoides (Rubiaceae) in northeastern Bolivian savannas. Because each bird species differs with respect to feeding and post-feeding behavior, we hypothesized that seed dispersal by each species will contribute differently to the rate of increase of G. viburnoides, but that seed dispersal by either species will increase population growth when compared to a scenario with no seed dispersal. To examine the effects of individual dispersers on the future population size …
A Three-Dimensional Computer Simulation Model Reveals The Mechanisms For Self-Organization Of Plant Cortical Microtubules Into Oblique Arrays, 2010 Texas A & M University - College Station
A Three-Dimensional Computer Simulation Model Reveals The Mechanisms For Self-Organization Of Plant Cortical Microtubules Into Oblique Arrays, Ezgi Can Eren, Ram Dixit, Natarajan Gautam
Biology Faculty Publications & Presentations
The noncentrosomal cortical microtubules (CMTs) of plant cells self-organize into a parallel three-dimensional (3D) array that is oriented transverse to the cell elongation axis in wild-type plants and is oblique in some of the mutants that show twisted growth. To study the mechanisms of CMT array organization, we developed a 3D computer simulation model based on experimentally observed properties of CMTs. Our computer model accurately mimics transverse array organization and other fundamental properties of CMTs observed in rapidly elongating wild-type cells as well as the defective CMT phenotypes observed in the Arabidopsis mor1-1 and fra2 mutants. We found that CMT …
Analysis Of Mirna Modifications, 2010 University of Nebraska-Lincoln
Analysis Of Mirna Modifications, Bin Yu, Xuemei Chen
School of Biological Sciences: Faculty Publications
After transcription, a large number of cellular RNAs employ modifications to increase their diversity and functional potential. Modifications can occur on the base, ribose, or both, and are important steps in the maturation of many RNAs. Our lab recently showed that plant microRNAs (miRNAs) possess a 2′-O-methyl group on the ribose of the 3′ terminal nucleotide, and that this methyl group is added after miRNA/miRNA* formation. One function of this modification is to protect miRNAs from 3′ terminal uridylation by an unknown enzymatic activity. It is possible that uridylation of miRNAs triggers their degradation. Here we describe a …
Phenotypic Plasticity In Juvenile Jellyfish Medusae Facilitates Effective Animal–Fluid Interaction, 2010 California Institute of Technology
Phenotypic Plasticity In Juvenile Jellyfish Medusae Facilitates Effective Animal–Fluid Interaction, J. C. Nawroth, K. E. Feitl, Sean Colin, John H. Costello, J. O. Dabiri
Arts & Sciences Faculty Publications
Locomotion and feeding in marine animals are intimately linked to the flow dynamics created by specialized body parts. This interaction is of particular importance during ontogeny, when changes in behaviour and scale challenge the organism with shifts in fluid regimes and altered functionality. Previous studies have indicated that Scyphozoan jellyfish ontogeny accommodates the changes in fluid dynamics associated with increasing body dimensions and velocities during development. However, in addition to scale and behaviour that—to a certain degree—underlie the control of the animal, flow dynamics are also dependent on external factors such as temperature. Here, we show phenotypic plasticity in juvenile …
The Importance Of Open Access In Technology Transfer For Marine Ornamental Aquaculture: The Case Of Hobbyist-Led Breeding Initiative, 2010 Roger Williams University
The Importance Of Open Access In Technology Transfer For Marine Ornamental Aquaculture: The Case Of Hobbyist-Led Breeding Initiative, Andrew L. Rhyne
Arts & Sciences Faculty Publications
Access to peer-reviewed literature is often restricted to a limited segment of the target audience. Barriers are in place to prevent open access information. Here, I present a case study of how the internet and hobbyists are transforming both access and flow of information from closed circles to open dialogue within the field of marine ornamental fish rearing. This open approach is leading to innovation a rate remarkably faster and at a lower costs than could have been accomplished by traditional methods. Aquaculture societies, aquarium professionals, hobbyists, and scientists pursuing the captive production of species should embrace this movement. Whether …
How U.S. Ocean Policy And Market Power Can Reform The Coral Reef Wildlife Trade, 2010 Washington State University
How U.S. Ocean Policy And Market Power Can Reform The Coral Reef Wildlife Trade, Brian N. Tissot, Barbara A. Best, Eric H. Borneman, Andrew W. Bruckner, Cara H. Cooper, Heather D’Agnes, Timothy P. Fitzgerald, Amanda Leland, Susan Lieberman, Amy Mathews Amos, Rashid Sumaila, Teresa M. Telecky, Frazer Mcgilvray, Brian J. Plankis, Andrew L. Rhyne, Glynnis G. Roberts, Benjamin Starkhouse, Todd C. Stevenson
Arts & Sciences Faculty Publications
As the world’s largest importer of marine ornamental species for the aquaria, curio, home décor, and jewelry industries, the United States has an opportunity to leverage its considerable market power to promote more sustainable trade and reduce the effects of ornamental trade stress on coral reefs worldwide. Evidence indicates that collection of some coral reef animals for these trades has caused virtual elimination of local populations, major changes in age structure, and promotion of collection practices that destroy reef habitats. Management and enforcement of collection activities in major source countries such as Indonesia and the Philippines remain weak. Strengthening US …
Effects Of Salinity On Reproduction And Survival Of The Calanoid Copepod Pseudodiaptomus Pelagicus, 2010 University of Florida
Effects Of Salinity On Reproduction And Survival Of The Calanoid Copepod Pseudodiaptomus Pelagicus, Cortney L. Ohs, Andrew L. Rhyne, Scott W. Grabe, Matthew A. Dimaggio, Erik Stenn
Arts & Sciences Faculty Publications
Four experiments were conducted on the calanoid copepod, Pseudodiaptomus pelagicus, to determine the effects of salinity on survival, development time, reproductive output, and population growth in order to define the optimal salinity for culture. To determine the appropriate experimental salinity range we exposed nauplii and adults to abrupt salinity changes from 35 g/L to 5, 10, 15, 35, 42, and 48 g/L at 30 °C and determined survival after 24 hours. The second experiment stocked early stage nauplii into 1 L beakers after which they were cultured using standard procedures for 10 days at six salinities (10, 15, 20, …
Chapter 27 – Studying Plus-End Tracking At Single Molecule Resolution Using Tirf Microscopy, 2010 Washington University in St Louis
Chapter 27 – Studying Plus-End Tracking At Single Molecule Resolution Using Tirf Microscopy, Ram Dixit, Jennifer L. Ross
Biology Faculty Publications & Presentations
The highly dynamic microtubule plus-ends are key sites of regulation that impact the organization and function of the microtubule cytoskeleton. Much of this regulation is performed by the microtubule plus-end tracking (+TIP) family of proteins. +TIPs are a structurally diverse group of proteins that bind to and track with growing microtubule plus-ends in cells. +TIPs regulate microtubule dynamics as well as mediate interactions between microtubule tips and other cellular structures. Most +TIPs can directly bind to microtubules in vitro; however, the mechanisms for their plus-end specificity are not fully understood. Cellular studies of +TIP activity are complicated by the fact …
Catalog Of The Coreidae, Or Leaf-Footed Bugs, Of The New World, 2010 Fort Hays State University
Catalog Of The Coreidae, Or Leaf-Footed Bugs, Of The New World, Richard J. Packauskas
Fort Hays Studies Series
Studies on the New World Coreidae have languished for more than a century. Neglect of these often large, abundant, and occasionally economically important bugs has been due, I believe, to the lack of means to identify them. Most literature treating the New World Coreidae has been restricted to the North American fauna, except for the recent efforts of Brailovsky (1975 to 2007).