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Full-Text Articles in Medicine and Health Sciences

Encapsulated Beta-Islet Cells As A Bioartificial Pancreas To Treat Insulin-Dependent Diabetes During Pregnancy, Stephen Hunter, Y. Wang, C. Weiner, Jennifer Niebyl May 2013

Encapsulated Beta-Islet Cells As A Bioartificial Pancreas To Treat Insulin-Dependent Diabetes During Pregnancy, Stephen Hunter, Y. Wang, C. Weiner, Jennifer Niebyl

Jennifer R Niebyl

OBJECTIVE: Our purpose was to determine the effectiveness of the bioartificial pancreas technique in correcting (1) maternal carbohydrate metabolism and (2) fetal malformation rates in a pregnant diabetic animal model. STUDY DESIGN: Insulin secretion from encapsulated rat islets cultured in the presence of homologous rat prolactin was determined and compared with that of controls. Streptozotocin-induced diabetic Balb/c mice were then transplanted with rat islet cells encapsulated within alginate microbeads and were then bred. Blood glucose determinations were made after transplantation and throughout gestation. Pups were delivered by cesarean section on day 19 of gestation. Outcome parameters from the transplanted study …


Vulvar Carcinoma With Hypercalcemia, Jennifer Niebyl, Rene Genadry, E. Friedrich, E. Wilkinson, J. Woodruff May 2013

Vulvar Carcinoma With Hypercalcemia, Jennifer Niebyl, Rene Genadry, E. Friedrich, E. Wilkinson, J. Woodruff

Jennifer R Niebyl

Hypercalcemia associated with nonmetastatic malignancy has been reported most frequently with lung or kidney tumors, while among gynecologic malignancies, the ovary has been the most common primary site. The pertinent clinicopathologic features of 2 cases of nonmetastatic vulvar carcinoma producing hypercalcemia are described in the present report. Including 3 previously reported cases, the vulva is seen to be the second most common site in the female genital tract for production of this paraendocrine syndrome. The clinician should be aware of the association of hypercalcemia and mental confusion with bulky vulvar tumors, so that surgery will not needlessly be delayed in …


Gonococcal Salpingitis In Pregnancy, Rene Genadry, B. Thompson, Jennifer Niebyl May 2013

Gonococcal Salpingitis In Pregnancy, Rene Genadry, B. Thompson, Jennifer Niebyl

Jennifer R Niebyl

No abstract provided.