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Full-Text Articles in Medicine and Health Sciences
Human Plasma Prekallikrein And High Molecular Weight Kininogen Decrease During Parturition, B. Alving, Jennifer Niebyl, D. Proud, B. Mason, J. Pisano
Human Plasma Prekallikrein And High Molecular Weight Kininogen Decrease During Parturition, B. Alving, Jennifer Niebyl, D. Proud, B. Mason, J. Pisano
Jennifer R Niebyl
Prekallikrein and high molecular weight kininogen were measured in plasma taken from nine women during parturition. Prekallikrein decreased significantly (p less than 0.01) from 1.49 +/- 0.15 S-2302 U/ml (mean +/- SEM) in early labor to 1.26 +/- 0.13 S-2302 U/ml in the immediate postpartum period. Immunoreactive high molecular weight kininogen also significantly decreased from 76 +/- 5 micrograms/ml to 68 +/- 5 micrograms/ml one day postpartum (p less than 0.01). Both proteins rose to normal levels within two days. The data suggest that the kallikrein-kinin system is utilized during parturition.
Drugs For Inhibition Of Premature Labor, Jennifer Niebyl
Drugs For Inhibition Of Premature Labor, Jennifer Niebyl
Jennifer R Niebyl
Effective inhibition of premature labor depends on prompt initiation of treatment. The author discusses factors initiating parturition, and the benefits and risks for mother and child of administration of alcohol, beta adrenergic agents, magnesium sulfate, and other agents that may counteract them.
Prostaglandin F Metabolite Concentration As A Prognostic Factor In Preterm Labor, C. Weitz, R. Ghodgaonkar, N. Dubin, Jennifer Niebyl
Prostaglandin F Metabolite Concentration As A Prognostic Factor In Preterm Labor, C. Weitz, R. Ghodgaonkar, N. Dubin, Jennifer Niebyl
Jennifer R Niebyl
Concentration of the 13,14-dihydro,15 keto-metabolite of prostaglandin F2 alpha (PGFM) was measured in women being observed for preterm labor. The mean initial PGFM level was significantly higher in patients who delivered preterm (65.9 +/- 9.7 pg/mL; N = 14) than in patients not in preterm labor (32.1 +/- 4.3 pg/mL; N = 11; P less than .01). Plasma PGFM concentrations decreased significantly during ritodrine therapy only in successfully treated patients (P less than .05). All patients with initial PGFM concentrations greater than or equal to 55 pg/mL delivered preterm. Two of four patients not considered to be in preterm labor …
Preterm Parturition. Prostaglandin Synthetase Inhibitors, Jennifer Niebyl
Preterm Parturition. Prostaglandin Synthetase Inhibitors, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.