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Full-Text Articles in Medicine and Health Sciences

Congenital Megacalycosis: A Rare Renal Developmental Anomaly, Beki̇r Suha Parlaktaş, Fi̇kret Erdemi̇r, Ni̇hat Uluocak Jan 2004

Congenital Megacalycosis: A Rare Renal Developmental Anomaly, Beki̇r Suha Parlaktaş, Fi̇kret Erdemi̇r, Ni̇hat Uluocak

Turkish Journal of Medical Sciences

ha PARLAKTAŞ, Fikret ERDEMİR, Nihat ULUOCAK Department of Urology, Faculty of Medicine, Gaziosmanpaşa University, Tokat - Turkey


Mechanisms Of Glybenclamide-Mediated Anti-Arrhythmia And Ischemic Conditionining In A Rat Model Of Myocardial Infarction: Role Of Yohimbine Treatment, Ömer Bozdoğan, Ersöz Gonca, Eylem Suveren Ti̇ryaki̇, Fati̇h Gökçe Jan 2004

Mechanisms Of Glybenclamide-Mediated Anti-Arrhythmia And Ischemic Conditionining In A Rat Model Of Myocardial Infarction: Role Of Yohimbine Treatment, Ömer Bozdoğan, Ersöz Gonca, Eylem Suveren Ti̇ryaki̇, Fati̇h Gökçe

Turkish Journal of Medical Sciences

Glibenclamide (Glyburide), a widely used second-generation sulfonylurea hypoglycemic agent, is a known specific blocker of adenosine triphosphate (ATP) sensitive potassium (K+) channels. Although the blockage of the ATP dependent potassium channel reduces arrhythmia, it increases enfarct size. Yohimbine is an alpha-2 blocker that reduces infarct size as suggested by several studies. We hypothesized that a combination of yohimbine and glibenclamide may be more effective in reducing the arrhythmia following ligation. The arteria descendence (LAD) branch of the left coronary artery in conscious rats was ligated and arrhythmia was recorded during the 15 min following coronary ligation. Sixteen hours after coronary …


Effects Of Weight Loss Induced By Eight-Week Orlistat Therapy On Maximal Work Production Capacity In Obese Females, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur Jan 2004

Effects Of Weight Loss Induced By Eight-Week Orlistat Therapy On Maximal Work Production Capacity In Obese Females, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur

Turkish Journal of Medical Sciences

The aim of this study was to examine the effects of weight loss induced by pharmacotherapy combined with a hypocaloric diet for a period of 8-weeks on maximal work (Wmax) production capacity and aerobic fitness in obese patients. Twelve obese females were put on an integrated energy restricted diet with orlistat supplement 3 x 120 mg/day. Each patient performed 3 incremental ramp exercise tests using an electromagnetically braked cycle ergometer: one at onset, one at the end of 4-weeks and one at the end of the 8-weeks to determine Wmax production capacity. The first 4-week therapy period resulted in a …


The Efficacy Of Intermittant Low-Dose Systemic Corticosteroid In The Treatment Of Alopecia Areata, Ahu Bi̇rol, Emel Erkek, Fatma Tuncez, Gülcan Saylam Kurti̇pek, Yeter Bağci, Mukadder Koçak Jan 2004

The Efficacy Of Intermittant Low-Dose Systemic Corticosteroid In The Treatment Of Alopecia Areata, Ahu Bi̇rol, Emel Erkek, Fatma Tuncez, Gülcan Saylam Kurti̇pek, Yeter Bağci, Mukadder Koçak

Turkish Journal of Medical Sciences

Alopecia areata (AA) is a common cause of non-scarring alopecia characterized by patchy hair loss. AA is difficult to treat because of its chronic and inflammatory nature. The aim of the present study was to investigate the effect of low-dose systemic corticosteroids in the treatment of AA. Fifteen patients with AA were included in this study. Systemic prednisolone 10-15 mg/day on 2 consecutive days per week for 6 months was administered. Fourteen patients (93.3%) had patchy alopecia areata. One patient (6.3%) had alopecia universalis. Seven (46.7%) patients showed complete healing, 5 (33.3%) showed partial response and 3 (20%) did not …


Neurilemmoma Originating From The Hypoglossal Nerve In The Floor Of The Mouth, Çağri Deli̇lbaşi, Hiroshi Kohara, Kana Takao, Seiji Iida, Mikihiko Kogo Jan 2004

Neurilemmoma Originating From The Hypoglossal Nerve In The Floor Of The Mouth, Çağri Deli̇lbaşi, Hiroshi Kohara, Kana Takao, Seiji Iida, Mikihiko Kogo

Turkish Journal of Medical Sciences

LİLBAŞI, Hiroshi KOHARA, Kana TAKAO, Seiji IIDA, Mikihiko KOGO Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry Osaka University, Osaka-Japan


Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan Jan 2004

Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan

Turkish Journal of Medical Sciences

AKDEMİR^1, Hüseyin GÜNDÜZ^2, Hakan ÖZHAN^1, Mehmet YAZICI^1, Enver ERBİLEN^1, Cihangir UYAN^2 ^1Department of Cardiology, Düzce Faculty of Medicine, Abant Izzet Baysal University, Düzce - Turkey ^2Department of Cardiology, Izzet Baysal Faculty of Medicine, Abant Izzet Baysal University, Bolu - Turkey


Reconstruction Of Localized Defects Of The Anterior Maxillary Ridge With Autogenous Bone Graft Before Insertion Of A Single Implant, Yilmaz Günaydin, Yavuz Si̇nan Aydintuğ, Keri̇m Ortakoğlu, Meti̇n Şençi̇men, Mehmet Dalkiz Jan 2004

Reconstruction Of Localized Defects Of The Anterior Maxillary Ridge With Autogenous Bone Graft Before Insertion Of A Single Implant, Yilmaz Günaydin, Yavuz Si̇nan Aydintuğ, Keri̇m Ortakoğlu, Meti̇n Şençi̇men, Mehmet Dalkiz

Turkish Journal of Medical Sciences

ÜNAYDIN^1, Yavuz Sinan AYDINTUĞ^1, Kerim ORTAKOĞLU^1, Metin ŞENÇİMEN^1, Mehmet DALKIZ^2 ^1Department of Oral and Maxillofacial Surgery, Gülhane Military Medical Academy, Ankara - Turkey ^2Department of Prosthetic Dentistry, Gülhane Military Medical Academy, Ankara - Turkey


What Is New In Wound Healing?, Senthil Kumar, Peng Foo Wong, David John Leaper Jan 2004

What Is New In Wound Healing?, Senthil Kumar, Peng Foo Wong, David John Leaper

Turkish Journal of Medical Sciences

Wound biology is complex. Wounds which were until recently seen only as defects in tissues are now increasingly interpreted in cellular and molecular terms. Growth factors, cytokines, proteases and adhesion molecules which participate in wound healing are discussed in this article. From a clinical perspective, conceptual shifts of importance, including moist wound healing, wound bed preparation and wound assessment, are presented. The frontiers of therapeutics employed in wound healing continue to advance with an increasing array of modalities joining the ranks at a regular pace. A range of currently available as well as evolving therapies- physical (topical negative pressure therapy, …


Adenoid Cystic Carcinoma Of The External Auditory Canal With Pulmonary Metastasis, Bumi̇n Deği̇rmenci̇, Ayli̇n Yücel, Murat Acar, Ramazan Albayrak Jan 2004

Adenoid Cystic Carcinoma Of The External Auditory Canal With Pulmonary Metastasis, Bumi̇n Deği̇rmenci̇, Ayli̇n Yücel, Murat Acar, Ramazan Albayrak

Turkish Journal of Medical Sciences

ĞİRMENCİ, Aylin YÜCEL, Murat ACAR, Ramazan ALBAYRAK Department of Radiology, Faculty of Medicine, Kocatepe University, Afyon - TURKEY


Spinocerebellar Ataxia With A Novel Chromosomal Defect: Del 5q34 - A Case Report, Ayşe Fi̇li̇z Koç, Yakup Sarica, Di̇lara Süleymanova Karahan Jan 2004

Spinocerebellar Ataxia With A Novel Chromosomal Defect: Del 5q34 - A Case Report, Ayşe Fi̇li̇z Koç, Yakup Sarica, Di̇lara Süleymanova Karahan

Turkish Journal of Medical Sciences

KOÇ^1, Yakup SARICA^1, Dilara SÜLEYMANOVA KARAHAN^2 ^1Department of Neurology, Faculty of Medicine, Çukurova University, Adana - Turkey ^2Department of Molecular Biology, Faculty of Medicine, Çukurova University, Adana - Turkey


Mesenchymal Chondrosarcoma Of The Mandible, Nusret Akpolat, Üzeyi̇r Gök Jan 2004

Mesenchymal Chondrosarcoma Of The Mandible, Nusret Akpolat, Üzeyi̇r Gök

Turkish Journal of Medical Sciences

KPOLAT^1, Üzeyir GÖK^2 ^1Department of Pathology, Faculty of Medicine, Fırat University, Elazığ - Turkey ^1Department of Otorhinolaryngology, Faculty of Medicine, Fırat University, Elazığ - Turkey


Recovery Of 1-Chloro-2,4-Dinitrobenzene Detoxification By N-Acetyl- L-Cysteine In Glutathione Predepleted Human Erythrocytes, Deni̇z Yildiz, C.Işil Kuran Jan 2004

Recovery Of 1-Chloro-2,4-Dinitrobenzene Detoxification By N-Acetyl- L-Cysteine In Glutathione Predepleted Human Erythrocytes, Deni̇z Yildiz, C.Işil Kuran

Turkish Journal of Medical Sciences

Glutathione is an important thiol-containing compound involved in the detoxification process in erythrocytes. Its thiol group reacts with a variety of xenobiotics in a glutathione S-transferase catalyzed reaction to form conjugates that are effluxed from the erythrocytes by an ATP dependent transport mechanism. A well studied experimental system is the transport of the conjugate of glutathione and 1-chloro-2,4-dinitrobenzene. We investigated whether N-acetyl-L-cysteine protects the free-SH content and restores 1-chloro-2,4-dinitrobenzene detoxification in erythrocytes or replaces glutathione in detoxification process in glutathione predepleted erythrocytes. Our results indicate that N-acetyl-L-cysteine restores the intracellular free-SH content following depletion by 1-chloro-2,4-dinitrobenzene and N-ethylmaleimide. N-acetyl-L-cysteine (10 …


Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale Jan 2004

Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale

Turkish Journal of Medical Sciences

Norfloxacin is a poorly water soluble drug, and to improve its solubility it was complexed with b-cyclodextrin (BCD). Several ocular patches/inserts of norfloxacin-b-cyclodextrin were prepared in hydroxypropyl methyl cellulose (HPMC) matrix. The influence of rate controlling membranes made of ethyl cellulose (EC) alone and in combination with polyvinyl pyrrolidone K30 (PVP K30) in different proportions on drug release kinetics was studied. The data were subjected to regression analysis. Various physical characteristics of the films were evaluated. In vitro release studies were carried out in a fabricated flow through cell. All the films prepared were found to be uniform in thickness, …


Brucellosis Seroprevalence In Southeast Turkey (Diyarbakır), Selahatti̇n Atmaca, Tuncer Özeki̇nci̇, Nezahat Akpolat, Saffet Elçi̇, Adnan Suay, Eralp Arikan Jan 2004

Brucellosis Seroprevalence In Southeast Turkey (Diyarbakır), Selahatti̇n Atmaca, Tuncer Özeki̇nci̇, Nezahat Akpolat, Saffet Elçi̇, Adnan Suay, Eralp Arikan

Turkish Journal of Medical Sciences

This study was conducted to determine brucellosis seropositivity in patients suspected of having brucellosis who sought treatment at the Central Laboratory of Dicle University Medical Faculty Hospital in southeast Turkey (Diyarbakır). 20,663 serum samples were collected during the study (1 August 2001-31 December 2002), and 14,480 sera were tested in a 12-month period on a seasonal basis by Rose-Bengal slide agglutination (RBSA), and positive sera were titrated by standard tube agglutination (STA). Titration values of 1/160 and above were considered positive. Of the 20663 sera, 463 (2.2%) tested positive on RBSA. Of these 463 sera, 267 (57.6%) tested positive on …


The Evaluation Of The Stomatognathic System Of A Group With Anterior Openbite, Semra Ci̇ğer, Eli̇f İdi̇l Keser Jan 2004

The Evaluation Of The Stomatognathic System Of A Group With Anterior Openbite, Semra Ci̇ğer, Eli̇f İdi̇l Keser

Turkish Journal of Medical Sciences

Anterior openbite (AOB) is a malocclusion considered to be associated with symptoms and signs of temporomandibular disorders (TMD). An accurate, objective and repeatable method is needed in order to clarify the relationship between TMD and anterior openbite. The aim of this study is to examine the functions of the stomatognathic systems of 21 adolescents with AOB by means of electrovibratography (EVG), electrognathography (EMG), electroganthography (EGN), and transcranial and cephalometric radiographs. Nonconcentricity and mild asymmetry of the condyle fossa relationships were observed on transcranial radiographs. EMG results showed that 85% of the subjects had abnormal swallowing patterns and 52% had abnormal …