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Articles 31 - 60 of 282
Full-Text Articles in Medicine and Health Sciences
Does Fibromyalgia Have An Effect On Hearing Loss In Women?, Zeli̇ha Kapusuz Gencer, Özlem Balbaloğlu, Mahmut Özkiriş, Levent Saydam
Does Fibromyalgia Have An Effect On Hearing Loss In Women?, Zeli̇ha Kapusuz Gencer, Özlem Balbaloğlu, Mahmut Özkiriş, Levent Saydam
Turkish Journal of Medical Sciences
Background/aim: Fibromyalgia (FM) patients may have several neuroendocrine dysfunctions, resulting in a hypervigilant sensory output that may be responsible for sensorineural complaints. In this study, we evaluated the audiological findings of a cohort of female fibromyalgia patients. Materials and methods: Between 1 September 2012 and 1 June 2013, 35 female FM patients, followed by the Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Bozok University, were recruited for the study. The patients were referred to the Department of Otolaryngology for routine otolaryngological and audiological evaluations. Age range was between 30 and 65 years, with a mean age of 48.10 …
Expression Profiles Of Cd11b, Galectin-1, Beclin-1, And Caspase-3 In Nasal Polyposis, Alper Di̇lci̇, Nuray Varol, İlker Kiliçcioğlu, Ece Konac, Utku Aydi̇l, Yusuf Kizil, Süleyman Sabri̇ Uslu
Expression Profiles Of Cd11b, Galectin-1, Beclin-1, And Caspase-3 In Nasal Polyposis, Alper Di̇lci̇, Nuray Varol, İlker Kiliçcioğlu, Ece Konac, Utku Aydi̇l, Yusuf Kizil, Süleyman Sabri̇ Uslu
Turkish Journal of Medical Sciences
Background/aim: Nasal polyposis is a chronic inflammatory disease affecting the paranasal sinuses and nasal mucosae. It is thought that genetic and molecular mechanisms in inflammatory and apoptotic pathways are the main factors in the etiopathogenesis of nasal polyposis. The aim of this study was to investigate the expression patterns of CD11b, galectin-1, beclin-1, and caspase-3 in nasal polyps.Materials and methods: The mRNA expression levels of CD11b, galectin-1, beclin-1, and caspase-3 protein and western blot analysis of caspase-3 protein were evaluated in inferior turbinate mucosae and nasal polyp tissues.Results: CD11b expression was markedly higher in nasal polyp tissues when compared to …
Tnf-Alpha 863c > A Promoter And Tnfrii 196t > G Exonic Variationsmay Be Risk Factors For Juvenile Idiopathic Arthritis, Bahadir Batar, Sezen Özman, Kenan Barut, Özgür Kasapçopur, Mehmet Güven
Tnf-Alpha 863c > A Promoter And Tnfrii 196t > G Exonic Variationsmay Be Risk Factors For Juvenile Idiopathic Arthritis, Bahadir Batar, Sezen Özman, Kenan Barut, Özgür Kasapçopur, Mehmet Güven
Turkish Journal of Medical Sciences
Background/aim: Juvenile idiopathic arthritis (JIA) is a chronic complex autoimmune disease. Genetic and environmental factors increase the risk of JIA. It is accepted that alterations in immune system pathways play an important role in the pathogenesis of JIA. The aim of the study was to investigate the possible association between immune system regulatory gene polymorphisms and JIA in Turkish patients. Materials and methods: We analyzed eight polymorphisms, TNF-alpha-863 C > A, TNFRII 196 T > G, IL2-631 G > A, IL13-1112 C > T, CCR2 190 G > A, CCR5delta32, CTLA4-1661 A > G, and PTPN22 1858 C > T, in 76 patients with JIA and in …
Topographic Methods To Expose The Exiting Points Of Supratrochlear, Supraorbital, And Zygomaticotemporal Nerves, Mesut Sabri̇ Tezer, İsmai̇l Yağmurhan Gi̇lan, Özlem Elvan, Vedi̇a Bennu Özcömert, Mustafa Akteki̇n
Topographic Methods To Expose The Exiting Points Of Supratrochlear, Supraorbital, And Zygomaticotemporal Nerves, Mesut Sabri̇ Tezer, İsmai̇l Yağmurhan Gi̇lan, Özlem Elvan, Vedi̇a Bennu Özcömert, Mustafa Akteki̇n
Turkish Journal of Medical Sciences
Background/aim: We evaluated the relations of the exiting points of supratrochlear (STN), supraorbital (SON), and zygomaticotemporal (ZTN) nerves with certain landmarks to provide improved anatomic knowledge. Materials and methods: The twenty-eight hemifaces of 5 fresh frozen and 11 embalmed heads (5 female and 11 male cadavers) were dissected. Distance and angular measurements were made between the exiting points of the nerves to the midline, lateral, and medial canthi. Comparisons of side, sex, and cadaver groups were evaluated.Results: Mean values were determined for all parameters. There was no difference between side measurements. There were significant differences between sexes and cadaver groups …
Molecular Analysis And Prevalence Of Huntington Disease In Northwestern Iran, Mahmoud Shekari Khaniani, Parisa Aob, Mohammadreza Ranjouri, Sima Mansoori Derakhshan
Molecular Analysis And Prevalence Of Huntington Disease In Northwestern Iran, Mahmoud Shekari Khaniani, Parisa Aob, Mohammadreza Ranjouri, Sima Mansoori Derakhshan
Turkish Journal of Medical Sciences
Background/aim: Huntington disease (HD) is a progressive adult-onset neurodegenerative disorder presenting an autosomal dominant inheritance. Since there is no information on the prevalence of HD in northwestern Iran, the aim of the present study was to determine the prevalence of HD and the number of CAG trinucleotide repeats in the population of northwestern Iran.Materials and methods: Genomic DNA was extracted from whole blood by the salting-out method. DNA samples were analyzed to determine the number of CAG trinucleotide repeats of the HD gene. An abnormally large number of CAG repeats, which is a diagnostic factor for the disease, was detected …
Three-Dimensional Evaluation Of Pelvic Posture In Adolescents With And Without A History Of Low Back Pain, Seher Özyürek, Arzu Genç, Hayri̇ye Kul Karaali̇, Zeli̇ha Candan Algun
Three-Dimensional Evaluation Of Pelvic Posture In Adolescents With And Without A History Of Low Back Pain, Seher Özyürek, Arzu Genç, Hayri̇ye Kul Karaali̇, Zeli̇ha Candan Algun
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the three-dimensional (3D) profile of pelvic posture and postural displacements of the pelvis in adolescents with and without a history of low back pain (LBP). Materials and methods: Thirty-two adolescents participated in this study. Participants were asked if they had ever suffered LBP at some point in their lives. Participants were divided into two groups: with a history of LBP (LBP group) and without a history of LBP (control group). For 3D evaluation of pelvic posture, the PosturePrint system was used. Three digital photographs were obtained in an upright stance (anteroposterior, left-right lateral) and …
Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout
Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout
Turkish Journal of Medical Sciences
Background/aim: Vaccines are often lyophilized in order to retain their stability and efficacy for a longer period of time. However, the same lyophilization process may also cause a major degradation of the vaccine, especially during early phases of manufacturing, leading to a loss of potency of the product. Many viral diseases, such as rabies, are acute and fatal unless the vaccine is administered prior to exposure or the onset of symptoms in the case of postexposure treatment. Materials and methods: We investigated the effect of lyophilization on the stability of the virus structure during rabies vaccine manufacturing using dynamic light …
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Turkish Journal of Medical Sciences
Background/aim: The objective of this study was to investigate and analyze the behavioral and neurochemical effects of monosodium glutamate (MSG) injections at various and subsequent dosages on male Wistar rats during the neonatal period. Materials and methods: In order to determine the behavioral and neurochemical effects of MSG, the experiment was implemented on neonatal male Wistar rats and the test was repeated for various MSG dosages. After completing the experiment, additionally, levels of dopamine, GABA, catecholamine (dopamine, noradrenaline, and adrenaline) and glutamate in the brain cells of the decapitated rats were also measured using the ELISA method. Results: Considering the …
Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca
Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA). Materials and methods: Arthritis was induced by the intradermal injection of chicken type II collagen with incomplete Freund's adjuvant into albino Wistar rats. Doses of 5 and 20 mg/kg GEM were administered twice a week after the 14th day, which marked the onset the arthritis. Serum IL-17, TNF-α, malondialdehyde, catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels and tissue heme oxygenase-1 (HO-1) and nuclear factor …
Plasma Human Leukocyte Antigen-G (Hla-G) In Patients With Thyroid Cancer, Murat Akin, Lati̇fe Arzu Aral, Aydin Yavuz, Harun Karabacak, Kürşat Di̇kmen, Hasan Bostanci
Plasma Human Leukocyte Antigen-G (Hla-G) In Patients With Thyroid Cancer, Murat Akin, Lati̇fe Arzu Aral, Aydin Yavuz, Harun Karabacak, Kürşat Di̇kmen, Hasan Bostanci
Turkish Journal of Medical Sciences
Background/aim: A number of tumor markers detected in the serum or pathological specimens using immunohistochemical methods are used for early detection of malignancies and postoperative follow-up. Human leukocyte antigen-G (HLA-G) is a nonclassic HLA class I molecule. Recent studies suggested a relationship between HLA-G positivity and the stage or the phenotype of the malignancy. In this study, the relationship between serum HLA-G positivity and thyroid cancer was investigated. Materials and methods: Fifty patients with thyroid cancer and 45 healthy volunteers were included in this study. Serum HLA-G levels were measured using ELISA. Results: HLA-G was positive in only 3 out …
Eleven Patients With Primary Thyroid Lymphoma: A Single Center Experience, Hasan Bostanci, Kürşat Di̇kmen, Nalan Akyürek, Ahmet Çağri Büyükkasap, Aydin Yavuz, Mehmet Muhi̇tti̇n Yalçin, Murat Akin
Eleven Patients With Primary Thyroid Lymphoma: A Single Center Experience, Hasan Bostanci, Kürşat Di̇kmen, Nalan Akyürek, Ahmet Çağri Büyükkasap, Aydin Yavuz, Mehmet Muhi̇tti̇n Yalçin, Murat Akin
Turkish Journal of Medical Sciences
Background/aim: Primary thyroid lymphoma (PTL) is a very rare thyroid malignancy. It should be diagnosed and treated immediately and accurately. Our aim was to evaluate the diagnostic methods and treatment results for patients with PTL.Materials and methods: We retrospectively evaluated the records of 11 patients with PTL from 2009 to 2015, diagnosed at our institute. Age, sex, stage, histopathologic type, presence of Hashimoto's thyroiditis, diagnostic methods, treatment types, and recurrence were examined.Results: Six patients were female, 5 were male, and the median age of the patients was 61 years (range: 15-76 years). All patients had a large palpable mass in …
Comparison Of Nutritional Risk Screening Tools For Predictingsarcopenia In Hospitalized Patients, Mehmet Yürüyen, Hakan Yavuzer, Serap Yavuzer, Mahi̇r Cengi̇z, Fi̇li̇z Demi̇rdağ, Zehra Kara, Suna Avci, Nurgül Özgür Yurttaş, Mehmet Sami̇ İslamoğlu, Eren İmre, Afrodi̇ta Zeynep Taşkin, Alper Döventaş, Ülev Deni̇z Erdi̇nçler
Comparison Of Nutritional Risk Screening Tools For Predictingsarcopenia In Hospitalized Patients, Mehmet Yürüyen, Hakan Yavuzer, Serap Yavuzer, Mahi̇r Cengi̇z, Fi̇li̇z Demi̇rdağ, Zehra Kara, Suna Avci, Nurgül Özgür Yurttaş, Mehmet Sami̇ İslamoğlu, Eren İmre, Afrodi̇ta Zeynep Taşkin, Alper Döventaş, Ülev Deni̇z Erdi̇nçler
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the risk of malnutrition in hospitalized patients with three different tests and to compare these tests in terms of long hospitalization periods and sarcopenia. Materials and methods: Hospitalized patients in an internal medicine clinic were enrolled in this cross-sectional study. Patients were grouped as under 65 years (Group 1 = G1) and over 65 years old (Group 2 = G2). The nutritional status of the patients was evaluated with the Nutritional Risk Screening (NRS) 2002, Universal Malnutrition Screening Tool (MUST), Mini Nutritional Assessment Short Form (MNA-SF), and total Mini Nutritional Assessment …
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Turkish Journal of Medical Sciences
Background/aim: Colorectal adenomatous polyps are precursors of colorectal cancer (CRC), which can be prevented with surveillance colonoscopy. This study aimed to assess risk factors for the recurrence of colorectal polyps and CRC following polypectomy. Materials and methods: In this single-center trial, a total of 510 patients who applied to the endoscopy unit of Hacettepe University Hospital for various reasons and who were diagnosed with at least one colorectal adenomatous polyp between 2000 and 2010 were retrospectively analyzed. Patients with colorectal adenomatous polyps or CRC recurrences were examined in terms of clinical and histological risk factors. Results: A total of 190 …
Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie
Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori (H. pylori) has a high prevalence in developing countries. We aimed to investigate the current prevalence of H. pylori, as well as its potential serum risk factors, in a population from southwest China.Materials and methods: This cross-sectional study included 10,912 subjects who received medical examinations at the First Affiliated Hospital of Chongqing Medical University in 2014. Data regarding physical examinations and biochemical measurements were collected, and H. pylori infection was diagnosed with a 13C-urea breath test. Logistic regression was conducted to identify the risk factors for H. pylori infection.Results: The infection rate of H. pylori was 34.4% …
Mean Adc Values Discriminate Rectal Mucinous Carcinomafrom Rectal Nonmucinous Adenocarcinoma, Hale Çolakoğlu Er, Gül Ayşe Erden
Mean Adc Values Discriminate Rectal Mucinous Carcinomafrom Rectal Nonmucinous Adenocarcinoma, Hale Çolakoğlu Er, Gül Ayşe Erden
Turkish Journal of Medical Sciences
Background/aim: This study aimed to differentiate rectal mucinous carcinoma (MC) from nonmucinous rectal adenocarcinoma (AC) using mean apparent diffusion coefficient (mADC) values obtained with diffusion-weighted imaging.Materials and methods: Sixty-two pathologically confirmed rectal AC (n = 44) and MC (n = 18) patients were included in this study. The two groups underwent pelvic MRI to determine the local staging baseline for rectal tumors. Once the region of interest (ROI) was determined, a border was drawn around each hyperintense tumor (b = 1000 s/mm2 images). Following a repeat of this procedure for each patient, the ROIs were recorded to apparent diffusion coefficient …
Reply To Letter To The Editor, Ju Tae Sohn
Reply To Letter To The Editor, Ju Tae Sohn
Turkish Journal of Medical Sciences
No abstract provided.
Superiorly Based Nasolabial Island Flap For Reconstruction Of The Lateral Lower Eyelid, Sedat Tatar, Yalçin Yontar, Selahatti̇n Özmen
Superiorly Based Nasolabial Island Flap For Reconstruction Of The Lateral Lower Eyelid, Sedat Tatar, Yalçin Yontar, Selahatti̇n Özmen
Turkish Journal of Medical Sciences
Background/aim: Various flap procedures have been described and used for the lower eyelids; however, the nasolabial flap is rarely employed. We herein aimed to present the clinical results of using the superiorly based nasolabial island flap for repair of surgical defects extending to the lateral lower eyelid. Materials and methods: Nine patients with a mean age of 62 +- 6 years underwent surgery for reconstruction of the lower eyelid.Results: The diagnosis of lesions was nodular basal-cell carcinoma (n = 5), superficial basal-cell carcinoma (n = 1), well-differentiated squamous-cell carcinoma (n = 1), and basosquamous-cell carcinoma (n = 2). According to …
Comparing The Effectiveness Of Ultrasound-Guided Versus Blind Steroid Injection In The Treatment Of Severe Carpal Tunnel Syndrome, Özgür Zeli̇ha Karaahmet, Eda Gürçay, Murat Kara, Azi̇ze Serçe, Zeynep Kiraç Ünal, Fatma Aytül Çakci
Comparing The Effectiveness Of Ultrasound-Guided Versus Blind Steroid Injection In The Treatment Of Severe Carpal Tunnel Syndrome, Özgür Zeli̇ha Karaahmet, Eda Gürçay, Murat Kara, Azi̇ze Serçe, Zeynep Kiraç Ünal, Fatma Aytül Çakci
Turkish Journal of Medical Sciences
Background/aim: This study aimed to compare the effectiveness of ultrasound (US)-guided injection versus blind injection of corticosteroids in the treatment of carpal tunnel syndrome (CTS). Materials and methods: This prospective, randomized clinical trial included patients with severe CTS based on clinical and electrophysiological criteria. The patients were evaluated for clinical and electrophysiological parameters at baseline and 4 weeks after treatment. Symptom severity and hand function were assessed by the Boston questionnaire. The patients underwent blind injection or US-guided injection. Results: When compared with baseline, both groups showed significant improvement in Boston questionnaire scores and all electrophysiological parameters. Significant differences were …
Associations Of Apgar Score And Size At Birth With Lipoprotein Subclasses In Juvenile Obesity, Osama Bekhet, Jelena Vekic, Aleksandra Zeljkovic, Dusan Paripovic, Tamara Gojkovic, Jelena Janac, Vesna Spasojevic-Kalimanovska, Amira Peco-Antic, Gordana Milosevski-Lomic, Zorana Jelic-Ivanovic, Aleksandra Stefanovic
Associations Of Apgar Score And Size At Birth With Lipoprotein Subclasses In Juvenile Obesity, Osama Bekhet, Jelena Vekic, Aleksandra Zeljkovic, Dusan Paripovic, Tamara Gojkovic, Jelena Janac, Vesna Spasojevic-Kalimanovska, Amira Peco-Antic, Gordana Milosevski-Lomic, Zorana Jelic-Ivanovic, Aleksandra Stefanovic
Turkish Journal of Medical Sciences
Background/aim: Juvenile obesity is associated with several metabolic abnormalities, one of them being atherogenic dyslipidemia. Suboptimal fetal growth is associated with obesity risk in childhood, but also with increased rate of metabolic diseases in later life. This study investigated associations of neonatal data (Apgar score, birth weight and birth length) with low-density lipoprotein and high-density lipoprotein (LDL and HDL) subclasses in a group of obese children, as well as a possible impact of breastfeeding duration on obesity-associated lipoprotein subclasses distributions.Materials and methods: We included 42 obese children, aged 14.2 ± 2.1 years. LDL and HDL subfractions were separated by gradient …
Isolation And Culture Of Adult Mouse Vestibular Nucleus Neurons, Aydin Hi̇m, Serap Altuntaş, Gürkan Öztürk, Ender Erdoğan, Nureddi̇n Cengi̇z
Isolation And Culture Of Adult Mouse Vestibular Nucleus Neurons, Aydin Hi̇m, Serap Altuntaş, Gürkan Öztürk, Ender Erdoğan, Nureddi̇n Cengi̇z
Turkish Journal of Medical Sciences
Background/aim: Isolated cell cultures are widely used to study neuronal properties due to their advantages. Although embryonic animals are preferred for culturing, their morphological or electrophysiological properties may not reflect adult neurons, which may be important in neurodegenerative diseases. This paper aims to develop a method for preparing isolated cell cultures of medial vestibular nucleus (MVN) from adult mice and describe its morphological and electrophysiological properties.Materials and methods: Vestibular nucleus neurons were mechanically and enzymatically isolated and cultured using a defined medium with known growth factors. Cell survival was measured with propidium iodide, and electrophysiological properties were investigated with current-clamp …
Histopathological Effects Of Mesenchymal Stem Cells In Ratswith Bladder And Posterior Urethral Injuries, Berat Di̇lek Demi̇rel, Ünal Biçakci, Riza Rizalar, Ferda Alpaslan Pinarli, Oğuz Aydin
Histopathological Effects Of Mesenchymal Stem Cells In Ratswith Bladder And Posterior Urethral Injuries, Berat Di̇lek Demi̇rel, Ünal Biçakci, Riza Rizalar, Ferda Alpaslan Pinarli, Oğuz Aydin
Turkish Journal of Medical Sciences
Background/aim: To evaluate the effects of mesenchymal stem cell (MSC) therapy in an experimental bladder and posterior urethral injury model. Materials and methods: The study subjects consisted of 40 male Wistar albino rats that were divided into four groups: control group (n = 10) (the bladder was only surgically opened and closed), sham group (n = 10) (surgical procedure), IVMSC group (n= 10) (surgical procedure and intravenous MSC treatment), and LMSC group (n = 10) (surgical procedure and local MSC treatment). Histopathological evaluation was performed for the degree of fibrosis and inflammation and the extent and intensity of staining of …
Interleukin-6 And Hepcidin Expression Changes In Cardiac Tissue Of Long-Term Trained And Untrained Rats After Exhaustive Exercise, Badegül Sarikaya, Ali̇ Doğan Dursun, Elçi̇n Yağmur Taylan Deveden, Lamia Pinar
Interleukin-6 And Hepcidin Expression Changes In Cardiac Tissue Of Long-Term Trained And Untrained Rats After Exhaustive Exercise, Badegül Sarikaya, Ali̇ Doğan Dursun, Elçi̇n Yağmur Taylan Deveden, Lamia Pinar
Turkish Journal of Medical Sciences
Background/aim: Exercise benefits the cardiovascular system, but strenuous exercise can cause cardiac damage and induce cytokine production, particularly that of interleukin-6 (IL-6). Hepcidin, which is primarily regulated by IL-6, increases after exercise. Hepcidin is a possible protective factor against the adverse effects of strenuous exercise such as oxidative stress. The aim of the study is to reveal that training increases hepcidin and attenuates increased levels of IL-6 in the hearts of exhaustively exercised rats by comparing the IL-6 and hepcidin mRNA expression levels in trained and untrained groups.Materials and methods: Thirty male Wistar albino rats were assigned to the following …
Effects Of N-Acetylcysteine On Ovarian Tissue Autografted Intogranulation Tissue Compared To Back Muscle In Rats, Farideh Daneshpoya, Mojtaba Karimipour, Masoumeh Zirakjavanmard, Bagher Pourheydar
Effects Of N-Acetylcysteine On Ovarian Tissue Autografted Intogranulation Tissue Compared To Back Muscle In Rats, Farideh Daneshpoya, Mojtaba Karimipour, Masoumeh Zirakjavanmard, Bagher Pourheydar
Turkish Journal of Medical Sciences
Background/aim: Ovarian transplantation can preserve fertility in cancer patients. The aim of this study was to compare ovarian transplantation into granulation tissue (GT) versus back muscle (BM) sites and also to investigate the effects of N-acetylcysteine (NAC) as an antioxidant on ovarian survival in a rat autograft model.Materials and methods: Twenty-eight adult female rats were divided into four equal groups (n = 7 each) as follows: Group 1, ovarian tissue grafted into GT + saline (GT + saline); Group 2, ovarian tissue grafted into GT + NAC (GT + NAC); Group 3, ovarian tissue grafted into BM + saline (BM …
Cardiac Mri And 3d Contrast-Enhanced Mr Angiography In Pediatric And Young Adult Patients With Turner Syndrome, Hasan Yi̇ği̇t, Aşan Önder, Senem Özgür, Zehra Aycan, Selmi̇n Karademi̇r, Vehbi̇ Doğan
Cardiac Mri And 3d Contrast-Enhanced Mr Angiography In Pediatric And Young Adult Patients With Turner Syndrome, Hasan Yi̇ği̇t, Aşan Önder, Senem Özgür, Zehra Aycan, Selmi̇n Karademi̇r, Vehbi̇ Doğan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to describe the spectrum and frequency of cardiovascular abnormalities in pediatric and young adult patients with Turner syndrome (TS) using cardiac MRI and MR angiography. Materials and methods: This prospective study consisted of 47 female patients of pediatric age and young adults with a karyotypically confirmed diagnosis of TS. All patients underwent cardiac MRI and contrast-enhanced MR angiography. A second examination after 9-26 months was performed for 28 of these patients. Results: Elongation of the transverse aortic arch (ETA) was the most frequent abnormality with a rate of 37%. The rate of partial anomalous pulmonary venous …
Endometriosis-Associated Changes In Serum Levels Of Interferons And Chemokines, Andrei Mihai Malutan, Tudor Drugan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Dan Mihu
Endometriosis-Associated Changes In Serum Levels Of Interferons And Chemokines, Andrei Mihai Malutan, Tudor Drugan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Dan Mihu
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to evaluate the serum concentration of main chemokines and interferons in patients with diagnosed endometriosis. Materials and methods: A total of 160 women were divided in two study groups (group 1 - endometriosis; group 2 - healthy women). Serum levels of IFN-α, IFN-γ, MCP-1, MIP-1α, MIP-1β, RANTES, eotaxin, IL-8, MIG, IP-10, and IL-17A were measured with Human Multiplex Cytokine Panels. Results. Serum levels of IFN-γ, MCP-1, and IL-8 were significantly higher (mean 14.03, 57.24, and 534.24, respectively, compared to 0.58, 20.51, and 259.82, respectively), and serum levels of IP-10 and eotaxin were significantly …
Using Fuzzy Logic For Diagnosis And Classification Of Spasticity, Veysel Alcan, Mehmet Rahmi̇ Canal, Murat Zi̇nnuroğlu
Using Fuzzy Logic For Diagnosis And Classification Of Spasticity, Veysel Alcan, Mehmet Rahmi̇ Canal, Murat Zi̇nnuroğlu
Turkish Journal of Medical Sciences
Background/aim: Spasticity is generally defined as a sensory-motor control disorder. However, there is no pathophysiological mechanism or appropriate measurement and evaluation standards that can explain all aspects of a possible spasticity occurrence. The objective of this study is to develop a fuzzy logic classifier (FLC) diagnosis system, in which a quantitative evaluation is performed by surface electromyography (EMG), and investigate underlying pathophysiological mechanisms of spasticity. Materials and methods: Surface EMG signals recorded from the tibialis anterior and medial gastrocnemius muscles of hemiplegic patients with spasticity and a healthy control group were analyzed in standing, resting, dorsal flexion, and plantar flexion …
Surgical Treatment Of Pulmonary Arteriovenous Malformations, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Ebru Sayilir, Hakan Ertürk, Yetki̇n Ağaçkiran, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Surgical Treatment Of Pulmonary Arteriovenous Malformations, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Ebru Sayilir, Hakan Ertürk, Yetki̇n Ağaçkiran, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
Background/aim: Pulmonary arteriovenous malformations (PAVMs) are direct communications between the branches of pulmonary arteries and veins. This study evaluates surgically treated cases of pulmonary arteriovenous malformations. Materials and methods: We retrospectively examined 41 cases of PAVM that were operated in our clinic between 1995 and 2012. We obtained the clinical, radiological, and surgical data of the patients from their files. Results: The 41 cases comprised 27 males and 14 females. Their mean age at diagnosis was 39.8 years (range: 9-71). The symptoms were hemoptysis in 28 cases, dyspnea in five, cough in three, and epistaxis in two; three patients were …
The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci
The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci
Turkish Journal of Medical Sciences
Background/aim: In this study, the aim is to investigate the prevalence of various coronary artery anomalies (CAAs), evaluated by 256-detector row coronary computed tomography (CCT), within the Turkish population. Materials and methods: We included 2973 patients who had received CCT. The high take-off right coronary artery (RCA) and left coronary artery (LCA), the RCA arising from the left sinus (LS), the LCA arising from the right sinus (RS), the circumflex artery (CX) arising from the RS, the single coronary ostium originating from the RS, the CX arising from the RCA, and the RCA arising from the pulmonary artery were evaluated. …
Physicochemical And Biochemical Parameters In Milk Of Serbian Breastfeeding Women, Slavica Sunaric, Marko Denic, Jelena Lalic, Tatjana Jovanovic, Ana Spasic, Jelena Zivkovic, Natasa Trutic, Gordana Kocic
Physicochemical And Biochemical Parameters In Milk Of Serbian Breastfeeding Women, Slavica Sunaric, Marko Denic, Jelena Lalic, Tatjana Jovanovic, Ana Spasic, Jelena Zivkovic, Natasa Trutic, Gordana Kocic
Turkish Journal of Medical Sciences
Background/aim: This study was undertaken to determine the changes and relationships between some important milk constituents as well as physical, rheological, and biochemical parameters of milk obtained from Serbian breastfeeding mothers. Materials and methods: Physicochemical and biochemical parameters and the concentrations of vitamins, uric acid, and minerals were determined during the three periods of lactation covering colostrum, transitional, and mature milk collected from 67 mothers who had a term-pregnancy. Results: Large interindividual variations regarding many parameters were found between mothers at the same period of lactation, but the average values were mostly in the expected and recommended ranges. For some …
Is Lower Uterine Segment Involvement A Prognostic Factor In Endometrial Cancer?, Sali̇m Erkaya, Murat Öz, Hasan Onur Topçu, Ali̇ Levent Şi̇rvan, Tayfun Güngör, Mehmet Mutlu Meydanli
Is Lower Uterine Segment Involvement A Prognostic Factor In Endometrial Cancer?, Sali̇m Erkaya, Murat Öz, Hasan Onur Topçu, Ali̇ Levent Şi̇rvan, Tayfun Güngör, Mehmet Mutlu Meydanli
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study is to investigate the prognostic significance of lower uterine segment (LUS) involvement in endometrial cancer (EC). Materials and methods: We reviewed the patients who were operated at our institution between July 2007 and March 2015 with the diagnosis of EC. Tumors localized in the corpus and involving the LUS or localized entirely in the LUS formed Group A, while tumors in the uterine corpus without LUS involvement formed Group B. Clinicopathological characteristics and survival of the patients were compared in both groups. Results: A total of 500 patients were included in the study. There …