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Articles 1 - 30 of 282
Full-Text Articles in Medicine and Health Sciences
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
Turkish Journal of Medical Sciences
Background/aim: Clinicians associate the changes in cervical lordosis with neck pain, but there is no clear consensus on this. We aimed to investigate the relationships of cervical angles, neck pain, disability, and the psychological status of the patients with acute and chronic neck pain. Materials and methods: A total of 110 patients with neck pain were included in this study. Demographic and clinical characteristics of the patients were recorded. The lordosis angle was determined by the posterior tangent method. A visual analog scale (VAS), the Neck Disability Index (NDI), and the Hospital Anxiety and Depression (HAD) scale were administered to …
Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k
Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k
Turkish Journal of Medical Sciences
Background/aim: This study aimed to compare the levonorgestrel intrauterine system (LNG-IUS) with abdominal hysterectomy (TAH) and total laparoscopic hysterectomy (TLH) as first-line treatments for heavy menstrual bleeding (HMB). Materials and methods: Ninety-eight patients aged 20-55 years who complained of regular heavy menstrual bleeding were enrolled in the study. The TAH group included 29 patients, the LNG-IUS group included 34, and the TLH group included 35. These groups were compared in terms of quality of life and the cost-effectiveness of the selected methods. Quality of life was assessed using the 36-Item Short Form (SF-36), and cost-effectiveness was assessed according to the …
Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur
Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP). Materials and methods: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated. Patients' demographic features and microbiological data were reviewed. Results: A total of 417 patients were clinically diagnosed with VAP; 51.1% of them were male and the average age was found as 69.9 ± 15.9 …
Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay
Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay
Turkish Journal of Medical Sciences
Background/aim: Understanding the causes of under-five deaths is key to realizing sustainable developmental goals. The aim of this descriptive study was to investigate the causes of under-five mortality in İstanbul during 2011 and compare the findings to those of 1988 and 2000. Materials and methods: All burial records of İstanbul were evaluated, and cemetery records of 1494 children, who died at under five years of age and were buried in İstanbul Metropolitan Municipality Cemeteries between 1 January and 31 December 2011, were analyzed. Several sociodemographic characteristics and causes of death were compared with the results of studies carried out in …
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Turkish Journal of Medical Sciences
Background/aim: Diabetic foot ulcers and related complications are a major cause of morbidity and hospital admissions. Our aim was to evaluate the risk factors associated with poor outcome in diabetic foot ulcers. Materials and methods: A prospective study was conducted on patients with diabetic foot ulceration attending the Madinah Teaching Hospital from June 2014 to December 2015. Potential risk factors and laboratory test results at presentation were recorded and their association with outcome (healing vs. amputation) was analyzed using IBM SPSS Statistics for Windows, Version 22.0. Results: In total, 112 patients were studied during our study period. The majority of …
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate and determine the relationships (if any) among pain, depression levels, fatigue, sleep quality, and quality of life in patients with rheumatoid arthritis (RA) aged 65 years and over, and to compare the results with those of RA patients under 65 years of age. Materials and methods: The study included 52 patients with RA aged 65 years and over (Group 1) and 84 patients with RA under 65 years of age (Group 2). Pain, depression levels, fatigue, sleep quality, quality of life, and disease activity of all of the participants were evaluated …
Three-Layer Primary Closure Of The Bipedicled Tram Flap Donor Site For Unilateralbreast Reconstruction: A 15-Year Experience With 124 Consecutive Patients, Hüseyi̇n Karagöz, Ci̇han Şahi̇n, Celaletti̇n Sever, Yalçin Külahci, Fi̇kret Eren, Ceyhun Cesur, Fuat Yüksel
Three-Layer Primary Closure Of The Bipedicled Tram Flap Donor Site For Unilateralbreast Reconstruction: A 15-Year Experience With 124 Consecutive Patients, Hüseyi̇n Karagöz, Ci̇han Şahi̇n, Celaletti̇n Sever, Yalçin Külahci, Fi̇kret Eren, Ceyhun Cesur, Fuat Yüksel
Turkish Journal of Medical Sciences
Background/aim: The pedicled transverse rectus abdominis myocutaneous (TRAM) flap remains widely used as a breast reconstruction technique. The bipedicled TRAM flap is not as preferable as it was formerly, mainly because of its donor site complications. However, in a number of situations, a bipedicled TRAM flap may be the only alternative. Therefore, a three-layer primary closure technique used with bipedicled TRAM flap breast reconstructions that can avoid donor site complications without using a mesh is presented. Materials and methods: A retrospective study was performed that included patients who underwent bipedicled TRAM flap breast reconstruction with the three-layer primary closure technique. …
Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin
Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin
Turkish Journal of Medical Sciences
Background/aim: PARV4, a small DNA virus belonging to the family Parvoviridae, was first isolated in an HBV injecting drug user. Several studies have investigated PARV4 co-infection with HBV and HCV and its effect on the progression of liver disease. The aim of this study was to determine the frequency of PARV4 among HBV-infected patients and healthy individuals. Materials and methods: A group of 90 HBV patients and a group of 90 healthy subjects were included in this study. Samples were selected after screening tests such as HBsAg ELISA, anti-HCV ELISA, and anti-HIV ELISA. Nested-PCRs were conducted to detect the PARV4 …
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the efficacy of the Artcure Diffusional Patch, which contains a mixture of 6 herbal oils (oleum thymi, oleum limonis, oleum nigra, oleum rosmarini, oleum chamomilla, oleum lauriexpressum) and has a hypoosmolar lipid structure, in the conservative treatment of lumbar disc herniation patients and to show the advantages and/or possibility of using this as an alternative method to surgery. Materials and methods: Of the 120 patients enrolled, 79 clinically diagnosed patients were included in the study. Clinical evaluations were performed on patients who had findings of protrusion or extrusion in their magnetic …
Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu
Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu
Turkish Journal of Medical Sciences
Background/aim: Resection of tumors from the groin and thigh regions with safe margins often results in significant soft tissue defects, which preclude primary closure. This study presents a series of rectus abdominis myocutaneous flaps for irradiated thigh and groin wounds with the purpose of evaluating the efficacy and outcomes of these flaps in this population. Materials and methods: From 2008 to 2015, all patients who underwent resection of thigh or groin region tumors and reconstruction with an inferiorly based rectus abdominis myocutaneous flap were retrospectively identified. Medical records of the patients were reviewed. Results: A total of 27 patients, aged …
Screening Of Immunocompromised Patients At Risk Of Strongyloidiasis In Western Turkey Using Elisa And Real-Time Pcr, Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyi̇n Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyi̇n Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan
Screening Of Immunocompromised Patients At Risk Of Strongyloidiasis In Western Turkey Using Elisa And Real-Time Pcr, Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyi̇n Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyi̇n Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan
Turkish Journal of Medical Sciences
Background/aim: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey. Materials and methods: Serum and stool samples were collected from 108 patients (25.9% of them were chronic renal failure and 74.1% were renal transplantation patients) who were admitted to Ege University Medical School in İzmir, located in western Turkey. Serum samples were analyzed by ELISA (DRG, Germany) and the presence of 18S rRNA gene of S. stercoralis was detected in stool samples by real-time …
Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce
Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the role of adjuvant therapy for stage I uterine leiomyosarcoma (LMS). Materials and methods: Clinicopathological data of cases of stage I uterine LMS from 1998 to 2015 were retrieved from the computerized database of Hacettepe University Hospital. The Kaplan-Meier method was used to estimate survival and progression-free survival, and survival differences were analyzed by log-rank test. Cox regression analysis was performed to account for the potential influence of confounding factors. Results: We evaluated the outcomes of 35 patients with histologically proven stage I LMS. The median age at diagnosis was 50 years. All patients …
Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki
Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki
Turkish Journal of Medical Sciences
Background/aim: Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. Materials and methods: We conducted a cross-sectional questionnaire-based study among a population of 2122 men who underwent andrological investigation for couple infertility. All participants were interviewed and their semen samples were analyzed. Information about medical history and occupational exposure was used to classify participants into exposed and unexposed …
A Comparison Of Usage Of The Laryngeal Mask Uniquetmin Denticulate And Edentulate Geriatric Patients, Meltem Genez, Semi̇h Küçükgüçlü, Şule Özbi̇lgi̇n, Bahar Kuvaki̇ Balkan, Tangül Beydeş, Melek Aksoy Sari
A Comparison Of Usage Of The Laryngeal Mask Uniquetmin Denticulate And Edentulate Geriatric Patients, Meltem Genez, Semi̇h Küçükgüçlü, Şule Özbi̇lgi̇n, Bahar Kuvaki̇ Balkan, Tangül Beydeş, Melek Aksoy Sari
Turkish Journal of Medical Sciences
Background/aim: Mask ventilation in geriatric and edentulous patients can be ineffective or even impossible because of the shape inside the patients' cheeks. For patients for whom a mask cannot be used for long, the use of a laryngeal mask can ease the administration of anesthesia. The aim of this study was to compare the use of the laryngeal mask UniqueTM in denticulate and edentulate patients aged over 65 years. Materials and methods: This prospective study included patients according to the American Society of Anesthesiologists I-III classification, aged 65 years or more. The patients were divided into two groups: a dentulous …
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Turkish Journal of Medical Sciences
Background/aim: The distribution and the demographic, etiological, and clinical features of autoimmune bullous diseases (ABDs) vary according to geographic regions of the world. The limited number of reported studies in Turkey are mostly retrospective and generally include only pemphigus. The aim of our study was to evaluate the demographic data, clinical features, associated triggering factors, and comorbidities in patients newly diagnosed with ABDs. Materials and methods: In this descriptive and prospective study, the demographic data, inhabited regions, smoking and drinking habits, presence of comorbidities, and specific and general potential triggering factors of ABDs considered by the patients were examined. Furthermore, …
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
Turkish Journal of Medical Sciences
Background/aim: This study aimed to describe the cultural adaptation of the Turkish Physical Activity Scale for the Elderly (PASE) and to examine the reliability and validity of the scale in older Turkish adults. Materials and methods: Eighty elderly people were recruited for the study. The assessments included the PASE, the International Physical Activity Questionnaire (IPAQ), the Short Physical Performance Battery and Short Form-36 Quality of Life Questionnaire (SF-36), and the Mini Mental State Test. Outcome measures were conducted twice within a week (test-retest) for reliability. Results: Cronbach's α coefficient was 0.714 for the initial evaluation. The intraclass correlation coefficient for …
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
Turkish Journal of Medical Sciences
Background/aim: Thoracic spine insufficiency is a subject of interest in neck problems. The aim was to investigate thoracic spinal curvature and mobility in subjects with and without chronic neck pain (CNP), cut-off points, and the relationship with pain. Materials and methods: Fifty-six patients with CNP (CNP group) and 53 healthy volunteers (control group) were included. Neck pain intensity of the patients was assessed by visual analogue scale and sagittal thoracic curvature and mobility of all participants were assessed by Spinal Mouse (Idiag, Fehraltorf, Switzerland). Results: Thoracic curvature was higher (P < 0.001) and mobility lower in the CNP group in comparison to the control group (P = 0.013). There was a positive correlation between pain intensity and thoracic curvature (r = 0.391, P < 0.001), while there was a negative correlation between pain intensity and thoracic mobility (r = -0.260, P = 0.006). For detecting neck pain, it was observed that the cut-off points for thoracic curvature and mobility were 45.5° and 30.0°, respectively. Conclusions: An increase in thoracic curvature of more than 45° and a decrease in mobility more than 30° may be critical for CNP patients.
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori is a pathogen that colonizes a majority of the world's population. Genetic diversity within the virulence genes of bacteria such as cagPAI and vacA may have a modified effect on the pathogenic potential of the bacteria. This study aimed to investigate which genes can be suggested as potentially related virulence factors for H. pylori-associated active chronic gastritis and stomach adenocarcinoma in the northwest of Iran and south of Turkey. Materials and methods: Formalin-fixed, paraffin-embedded stomach biopsy tissue samples were obtained from Iranian and Turkish patients from selected geographical regions. The prevalence of selected cagPAI genes and vacA …
Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed
Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed
Turkish Journal of Medical Sciences
Background/aim: This study aimed to find a link between sperm mitochondrial DNA mutations and male infertility in Pakistan. Materials and methods: DNA from semen samples was extracted and amplified by PCR using 7.8-kb deletion-specific primers. The PCR products were separated on agarose gel, visualized under UV-illumination, and then photographed. The results were genotyped and the data were analyzed using SPSS. Results: Deletion analysis of the 8.7-kb fragment by long PCR revealed multiple deletions. The frequency of deletion was much higher in infertile groups as compared to the control group. Further, on comparison between different subtypes of infertile groups, the deletions …
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Turkish Journal of Medical Sciences
Background/aim: Increased airway resistance reduces the effectiveness of ventilation treatment. Endotracheal tubes (ETTs) and connectors contribute to resistance. However, the effect of a closed system suction (CSS) connector is not well known. We compared the in vivo resistance occurring with a CSS connector with that of the standard connector. Materials and methods: This prospective study was conducted at Gazi University Hospital's neonatal intensive care unit. Intubated neonates were studied for two cycles; each cycle contained two periods of ETT + connector pairs (15 min/period) as follows: cycle 1 [A: long ETT + standard connector; B: long ETT + CSS connector] …
First Trimester Ultrasonographic Parameters In Prediction Of The Course And Outcome Of Monochorionic Twin Pregnancies, Slavica Aksam, Snezana Plesinac, Jelena Dotlic, Jasmina Tadic, Svetlana Vrzic-Petronijevic, Milos Petronijevic, Dusica Kocijancic-Belovic, Snezana Buzadzic
First Trimester Ultrasonographic Parameters In Prediction Of The Course And Outcome Of Monochorionic Twin Pregnancies, Slavica Aksam, Snezana Plesinac, Jelena Dotlic, Jasmina Tadic, Svetlana Vrzic-Petronijevic, Milos Petronijevic, Dusica Kocijancic-Belovic, Snezana Buzadzic
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to evaluate the association and the potential predictive value of first trimester ultrasonographic parameters on the course and outcome of monochorionic diamniotic twin pregnancies. Materials and methods: A prospective cohort study was undertaken of 39 healthy women with consecutive monochorionic diamniotic twin pregnancies. During first-trimester screening, crown-rump length (CRL) and nuchal translucency (NT) were measured. The intertwin discordance in CRL and NT was determined. As pregnancy outcomes we assessed twins' live-born rates, Apgar scores, birth weight, pregnancy complications, and gestational week of delivery. Results: None of the assessed pregnancy outcomes significantly correlated with …
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus (DM) is one of the most common metabolic diseases seen in the world today. Diabetic neuropathy (DN) is a chronic complication of the disease that is rarely reported in children, since it has a relatively longer latency period. Our main objective in this study is to determine the incidence rate of DN in pediatric DM patients and assess the risk factors associated with DN. Materials and methods: Data from 111 patients from January 2011 to May 2014 were reviewed in a retrospective manner. Nerve conduction studies were performed as the gold standard in diagnosis. Results: The incidence …
Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven
Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven
Turkish Journal of Medical Sciences
Background/aim: Albumin is the most important protein synthesized by the liver. Posttranscriptional changes occur in the molecular structure of albumin due to various factors and isoforms arise. Ischemic modified albumin (IMA) is one such isoform. This study was conducted to evaluate serum IMA concentrations in patients with hepatitis B virus (HBV)-related chronic liver diseases. Materials and methods: This study included 74 treatment-naive chronic hepatitis B patients, 25 patients with HBV-related cirrhosis, and 49 healthy controls. Serum IMA concentration was measured spectrophotometrically using the albumin cobalt binding test. Results: The mean IMA concentrations in the chronic hepatitis B group and healthy …
Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük
Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük
Turkish Journal of Medical Sciences
Background/aim: This study aimed to generate data for the S1 and S2 alar pedicle and body and the alar orientations for both dysmorphic and normal sacra. Materials and methods: The study comprised two groups: Group N consisted of 53 normal sacra and Group D included 10 dysmorphic sacra. Various features such as alar pedicle circumference; anterior, middle, and posterior axis of the sacral ala; sacral body height and width; and sagittal thickness were measured. Results: In group N, the median anterior axis of the alae was observed to be 30° on the right and 25° on the left, the median …
Frequency And Molecular Characterization Of Human Norovirus In Erzurum, Turkey, Mehmet Özkan Ti̇murkan, Hakan Aydin, Osman Aktaş
Frequency And Molecular Characterization Of Human Norovirus In Erzurum, Turkey, Mehmet Özkan Ti̇murkan, Hakan Aydin, Osman Aktaş
Turkish Journal of Medical Sciences
Background/aim: There are limited studies on genotyping and phylogenetic analysis of norovirus in Turkey, and this has not previously been studied in the Eastern Anatolia region. The aim of the present study was to determine the norovirus profile in this region with genotyping and phylogenetic analysis. Materials and methods: Included in the study were stool samples obtained from 427 people from different age groups in Eastern Anatolia. The nucleic acid samples isolated by the automatic system and nucleic acid sequence reactions and phylogenetic analyses were performed on RNA samples. Results: The presence of norovirus was detected in 86 (20.1%) of …
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
Turkish Journal of Medical Sciences
Background/aim: One of the factors that affect the occurrence of acne is the presence of Propionibacterium acnes. The present study was conducted to compare the culture and polymerase chain reaction (PCR) methods for identifying P. acnes in lesions isolated from patients with acne. Materials and methods: To examine the presence of P. acnes, 70 samples of acne lesions were collected. Microbial culture and the PCR molecular technique were used to identify P. acnes. Results: Of the total of 70 samples, 14 cases (20%) were identified as P. acnes positive using microbial culture and 58 cases (82.85%) using PCR. The results …
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Turkish Journal of Medical Sciences
Background/aim: IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS are mutations covering 76% of all the β-globin mutations in the Turkish population. In this study, our aim is to develop a reliable, fast, real-time kit for these mutations using the TaqMan probe method. Materials and methods: This study included 100 individuals with beta-thalassemia or sickle cell anemia who had unknown mutations, and 21 controls with known mutations. Results: We designed a kit containing the IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS …
Isolation Rates And Antibiotic Susceptibilities Of Different Enterobacteriaceae Species As Urinary Tract Infection Agents In Turkey: A Systematic Review, Caner Yürüyen, Yeşi̇m Gürol, Sabi̇re Ferda Kaleağasioğlu, Eli̇f Çi̇ğdem Kaspar, Gülden Yilmaz
Isolation Rates And Antibiotic Susceptibilities Of Different Enterobacteriaceae Species As Urinary Tract Infection Agents In Turkey: A Systematic Review, Caner Yürüyen, Yeşi̇m Gürol, Sabi̇re Ferda Kaleağasioğlu, Eli̇f Çi̇ğdem Kaspar, Gülden Yilmaz
Turkish Journal of Medical Sciences
Background/aim: In Turkey, few systematic reviews have analyzed the results of studies on the isolation rates of urinary tract infection agents and their antibiotic susceptibilities. This review was done to fill this gap and enable the correct application of guideline-based medical therapy by determining the isolation rates and antibiotic susceptibilities of different Enterobacteriaceae species in Turkey. Materials and methods: Relevant studies found from various databases with the help of previously specified search strategies were examined and eliminated according to eligibility criteria. The remaining 22 studies were included in this systematic review. Results: Escherichia coli was the most frequently isolated species …
Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout
Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout
Turkish Journal of Medical Sciences
Background/aim: Vaccines are often lyophilized in order to retain their stability and efficacy for a longer period of time. However, the same lyophilization process may also cause a major degradation of the vaccine, especially during early phases of manufacturing, leading to a loss of potency of the product. Many viral diseases, such as rabies, are acute and fatal unless the vaccine is administered prior to exposure or the onset of symptoms in the case of postexposure treatment. Materials and methods: We investigated the effect of lyophilization on the stability of the virus structure during rabies vaccine manufacturing using dynamic light …
The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k
The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Acetylsalicylic acid (ASA) treatment in diabetic patients is very important owing to the increasing hyperactivity of thrombocytes and atherosclerosis. In several investigations, it was reported that diabetes caused increased coronary artery disease, cerebrovascular disease, and death. In this study, we aimed to investigate the effect of ASA on osmoregulation, glycemic control, and some biochemical parameters in rats induced with experimental diabetes type 2. Materials and methods: Twenty-four rats were randomly divided in four groups: control (I), ASA control (II), diabetic (III), and ASA diabetic (IV). Diabetes was induced by streptozotocin treatment (30 mg/kg, twice, intraperitoneal injection) in obese rats. …