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Articles 421 - 429 of 429
Full-Text Articles in Medicine and Health Sciences
Inhibition Modifies The Effects Of Slow Calcium-Activated Potassium Channels On Epileptiform Activity In A Neuronal Network Model, Keun-Hang Susan Yang, Piotr J. Franaszczuk, Gregory K. Bergey
Inhibition Modifies The Effects Of Slow Calcium-Activated Potassium Channels On Epileptiform Activity In A Neuronal Network Model, Keun-Hang Susan Yang, Piotr J. Franaszczuk, Gregory K. Bergey
Mathematics, Physics, and Computer Science Faculty Articles and Research
Generation of epileptiform activity typically results from a change in the balance between network excitation and inhibition. Experimental evidence indicates that alterations of either synaptic activity or intrinsic membrane properties can produce increased network excitation. The slow Ca2+-activated K+ currents (sI AHP) are important modulators of neuronal firing rate and excitability and have important established and potential roles in epileptogenesis. While the effects of changes in sI AHP on individual neuronal excitability are readily studied and well established, the effects of such changes on network behavior are less well known. The experiments here utilize a defined small network model of …
The Effect Of Antioxidant Supplementation On Human Sperm Cryopreservation, Katrina E. Taylor
The Effect Of Antioxidant Supplementation On Human Sperm Cryopreservation, Katrina E. Taylor
Theses : Honours
Semen cryopreservation has an important role in assisted reproductive technology however, the cooling, freezing and thawing processes often result in a significant loss of sperm motility, viability and nuclear integrity. The destructive effects of cryopreservation are significantly exacerbated in samples exhibiting low sperm number and poor morphological characteristics. Recent research into infertility has focused on the correlation between excessive oxidation and subfertility, in particular radical induced lipid peroxidation within the phospholipid bilayer of the spermatozoon plasma membrane and the promotion of cellular damage as a result of antioxidant insufficiency. The aim of this study was to evaluate the effect of …
Characterization Of Migrating Cells From Ventricular Zone (Vz) To Distant Limbic Structures After Multiple Neonatal Seizures, Melissa Corcia
Characterization Of Migrating Cells From Ventricular Zone (Vz) To Distant Limbic Structures After Multiple Neonatal Seizures, Melissa Corcia
Seton Hall University Dissertations and Theses (ETDs)
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Sport In Canada: A History, Donald Morrow, Kevin Wamsley
Sport In Canada: A History, Donald Morrow, Kevin Wamsley
Donald Morrow
No abstract provided.
Castration Inhibits The Exercise-Induced Accumulation Of Hsp70 In Male Rodent Cardiac Muscle Tissue, Kevin Milne, David Thorp, C.W. Melling, Earl Noble
Castration Inhibits The Exercise-Induced Accumulation Of Hsp70 In Male Rodent Cardiac Muscle Tissue, Kevin Milne, David Thorp, C.W. Melling, Earl Noble
Jamie Melling
Intense exercise leads to accumulation of the inducible member of the 70-kDa family of heat shock proteins, Hsp70, in male, but not female, hearts. Estrogen is at least partially responsible for this difference. Because androgen receptors are expressed in the heart and castration leads to decreases in calcium regulatory proteins and altered cardiac function, testosterone (T) or its metabolites could also be involved. We hypothesized that removal of endogenous T production through castration would reduce cardiac Hsp70 accumulation after an acute exercise bout, whereas castrated animals supplemented with 5α-dihydrotestosterone (DHT) would show the intact male response. Fifty-four 8-wk-old male Sprague-Dawley …
Which Drugs Cause Cancer? Animal Tests Yield Misleading Results, Andrew Knight, Jarrod Bailey, Jonathan P. Balcombe
Which Drugs Cause Cancer? Animal Tests Yield Misleading Results, Andrew Knight, Jarrod Bailey, Jonathan P. Balcombe
Jonathan Balcombe, Ph.D.
No abstract provided.
Adolescent Malnutrition In Developing Countries A Close Look At The Problem And At Two National Experiences, Lorraine Cordeiro, Sascha Lamstein, Zeba Mahmud, F. James Levinson
Adolescent Malnutrition In Developing Countries A Close Look At The Problem And At Two National Experiences, Lorraine Cordeiro, Sascha Lamstein, Zeba Mahmud, F. James Levinson
Lorraine Cordeiro
No abstract provided.
Conservation And Development Interventions At The Wildlife-Livestock Interface, Steven A. Osofsky, Sarah Cleaveland, William B. Karesh, Michael D. Kock, Philip J. Nyhus, Lisa Starr, Angela Yang
Conservation And Development Interventions At The Wildlife-Livestock Interface, Steven A. Osofsky, Sarah Cleaveland, William B. Karesh, Michael D. Kock, Philip J. Nyhus, Lisa Starr, Angela Yang
Philip J. Nyhus
No abstract provided.
Spiroplasma Atrichopogonis Sp. Nov., From A Ceratopogonid Biting Midge, R. Thomas Koerber, Gail E. Gasparich, Mark F. Frana, William L. Grogan