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2015

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Full-Text Articles in Life Sciences

Critical Forces That Structure Subtidal Ecological Communities In The Gulf Of Maine, And The Integration Of Invasive Species Into These Communities, Martine C. Wagstaff Dec 2015

Critical Forces That Structure Subtidal Ecological Communities In The Gulf Of Maine, And The Integration Of Invasive Species Into These Communities, Martine C. Wagstaff

Graduate Doctoral Dissertations

Shallow subtidal epibenthic communities worldwide are under threat from exploitation, pollution, eutrophication, acidification, climate change, and invasive species, with implications for ecosystem diversity, productivity, function, and services. Subtidal ecosystems in the Gulf of Maine are particularly impacted, making it crucial to understand these habitats so that our impacts can be predicted and mitigated. I investigated the basic ecological forces that structure shallow subtidal epibenthic communities in this region, and how invasive species integrate themselves into these communities. I used community phylogenetic and functional trait analyses to investigate if invertebrate communities in the rocky subtidal are assembled via deterministic or random ...


Examining Sociological Differences And The Influence Of Prey Distribution And Environmental Variability In The Distribution Of A Top Marine Predator, The Bottlenose Dolphin (Tursiops Truncatus), Stefanie K. Gazda Dec 2015

Examining Sociological Differences And The Influence Of Prey Distribution And Environmental Variability In The Distribution Of A Top Marine Predator, The Bottlenose Dolphin (Tursiops Truncatus), Stefanie K. Gazda

Graduate Doctoral Dissertations

The purpose of this dissertation was to examine the influence of environmental variability on the distribution of prey, and the influence of prey spatial structure and habitat variability may have on the distributions of bottlenose dolphins (Tursiops truncatus). Additionally I examined how sociological differences (behavior type and the changes in a foraging behavior specific to Cedar Key Florida) influences the relative roles of bottlenose dolphins within the population.

The Gowans et al. scheme assumes that small groups form small communities and that foraging groups are small and rare as there are few foraging benefits to promote grouping. Using network analysis ...


Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird Dec 2015

Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird

Biological Sciences Faculty Publications

Haldane's Rule and Darwin's Corollary to Haldane's Rule are the observations that heterogametic F1 hybrids frequently are less fit than their homogametic siblings and that asymmetric results often are obtained from reciprocal hybrid crosses. In Caenorhabditis, Haldane's Rule and Darwin's Corollary have been observed in several hybrid crosses, including crosses of Caenorhabditis briggsae and Caenorhabditis nigoni. Fertile F1 females are obtained from reciprocal crosses. However, F1 males obtained from C. nigoni mothers are sterile and F1 males obtained from C. briggsae die during embryogenesis. We have identified cbr-him-8 as a recessive maternal-effect suppressor of F1 ...


2015 Final Report: Status Of The Arizona Toad (Anaxyrus Microscaphus) In New Mexico, Mason J. Ryan, Ian M. Latella, Jacek T. Giermakowski, Howard L. Snell Dec 2015

2015 Final Report: Status Of The Arizona Toad (Anaxyrus Microscaphus) In New Mexico, Mason J. Ryan, Ian M. Latella, Jacek T. Giermakowski, Howard L. Snell

Biology Faculty & Staff Publications

In 2013, we initiated a field study to assess the status of the Arizona Toad (Anaxyrus microscaphus) in New Mexico. Herein we provide the results of three years (2013-2015) of range-wide population monitoring, a review of threat assessments, and several contributions to the basic ecology of the Arizona Toad in New Mexico. This work highlights the sensitivity of the species to abiotic factors and emphasizes the nature of annual population fluctuations in a variable environment. We provide analyses of environmental factors that influence toad reproductive behaviors, employ occupancy and detection modeling at breeding sites, and provide analyses of tadpole habitat ...


Moths Fight Back: Arms Race In The Cloud Forest, Diana Pamela Rivera Dec 2015

Moths Fight Back: Arms Race In The Cloud Forest, Diana Pamela Rivera

Theses

Moths and bats engage in a coevolutionary arm race, where the same signals bats use to find moths are being used by moths to avoid bats. Moths evolve not only behavioral but acoustic responses to avoid predation by bats. This research examines one small component of a complex, multispecies arm race between moths and bats. In this study we found that the moth Amastus hyalina displayed both flight and acoustic responses to ultrasonic stimuli.

In tethered flight the tiger moth Amastus hyalina (Arctiinae) exhibits a complex array of reactions to ultrasonic tones that includes changes in flight and production of ...


Provisioning And Its Effects On The Social Interactions Of Tibetan Macaques (Macaca Thibetana) At Mt. Huangshan, China, Brianna I. Schnepel Dec 2015

Provisioning And Its Effects On The Social Interactions Of Tibetan Macaques (Macaca Thibetana) At Mt. Huangshan, China, Brianna I. Schnepel

All Master's Theses

The dispersal patterns of food resources has a significant effect on the composition of primate groups and social interactions within those groups. Humans often alter the dispersal of food. Non-humans often use affiliative behaviors to elicit tolerance or support from other group members. I investigated whether provisioned food resources alter the social interactions and group dynamics of Macaca thibetana. All-occurrence sampling and scan sampling were used for data recorded by camera traps. Trail-cameras were placed at six locations that contain natural and human food resources and recorded 60-second videos. Social behavior and proximity of the monkeys were recorded. I found ...


Effects Of Melatonin On Heartbeat And Possible Identification Of A Melatonin Receptor In Drosophila Melanogaster, Tricia L. Vankirk Dec 2015

Effects Of Melatonin On Heartbeat And Possible Identification Of A Melatonin Receptor In Drosophila Melanogaster, Tricia L. Vankirk

Electronic Theses and Dissertations

Chapter 1 of this manuscript is a literature review that serves as an introduction to the entire dissertation. Chapter 2 examines the effects of the melatonin injection on heart rate and rhythmicity in Drosophila melanogaster Canton-S (wild-type) pupae and pupae bearing a variety of heart mutations. Chapter 3 investigates further the possible mechanisms of melatonin’s ability to increase heart rhythmicity without significantly affecting heart rate. A melatonin antagonist, luzindole; a high-affinity melatonin agonist, 2-iodomelatonin and RNAi techniques are used to identify a possible melatonin receptor in Drosophila melanogaster.

An appendix contains a previously published manuscript detailing experiments performed at ...


The Integration Of African Americans In The Civilian Conservation Corps In Massachusetts, Caitlin E. Pinkham Dec 2015

The Integration Of African Americans In The Civilian Conservation Corps In Massachusetts, Caitlin E. Pinkham

Graduate Masters Theses

The Civilian Conservation Corps employed young white and black men between the ages of eighteen and twenty-five. In 1935 Robert Fechner, the Director of the Civilian Conservation Corps, ordered the segregation of Corps camps across the country. Massachusetts’ camps remained integrated due in large part to low funding and a small African American population. The experiences of Massachusetts’ African American population present a new general narrative of the Civilian Conservation Corps. The Federal government imposed a three percent African American quota, ensuring that African Americans participated in Massachusetts as the Civilian Conservation Corps expanded. This quota represents a Federal acknowledgement ...


Testing The Efficacy Of Lsn2463359, A Metabotropic Glutamate 5 Receptor Positive Allosteric Modulator, In Animal Models Of Schizophrenia, Dierdre M. Freamon Dec 2015

Testing The Efficacy Of Lsn2463359, A Metabotropic Glutamate 5 Receptor Positive Allosteric Modulator, In Animal Models Of Schizophrenia, Dierdre M. Freamon

Seton Hall University Dissertations and Theses (ETDs)

For many years the dominant theory surrounding the cause of schizophrenia was focused on elevated dopamine levels found in critical areas of the brain. Recently a new theory has emerged pointing to elevated glutamate levels resulting from hypofunction of NMDA receptors and hypoactivity of GABAergic neurons which normally inhibit glutamatergic cells in a tonic manner. Therefore, while traditional antipsychotics directly block dopamine receptors, some of the newly generated compounds are designed to modulate glutamate to normal levels.

I propose testing the efficacy of the metabotropic glutamate 5 receptor modulator LSN2463359, previously shown to act as an indirect agonist of the ...


Living With Coyotes, Owen H. Agnew Dec 2015

Living With Coyotes, Owen H. Agnew

Capstones

Coyotes have been slowly moving into New York State from Canada since the 1930s. They reached Westchester County and the Bronx decades ago, and their numbers have been slowly rising. Sighting in Manhattan reached an all-time high last spring, and pet attacks in Westchester County have increased slightly in the last several years. But the slight increase in sightings and pet attacks in recent years has been amplified on social media in towns like Chappaqua, New York, where anxiety and fear about coyotes has pitted neighbors against neighbors.

Main character Frank Vincenti is a Long Island barber and a self-proclaimed ...


Special Muscles, Annamaria C. Scaccia Dec 2015

Special Muscles, Annamaria C. Scaccia

Capstones

Special Muscles is a documentary that explores living with Duchenne muscular dystrophy, a fatal degenerative disease that weakens the muscles at an aggressive rate. The film will give an uncensored look at how one family copes with inevitability of the disease and their journey chasing a promising experimental cure.

Special Muscles follows 7-year-old Pietro Scarso and his family as they face the challenges, complications and promise of treating Pietro’s progressive muscle disorder. The film travels from New York to Los Angeles to Philadelphia to document the Scarso family’s race against time as Pietro undergoes a 96-week clinical trial ...


Quantifying The Adaptive Cycle, David G. Angeler, Craig R. Allen, Ahjond S. Garmestani, Lance H. Gunderson, Olle Hjerne, Monika Winder Dec 2015

Quantifying The Adaptive Cycle, David G. Angeler, Craig R. Allen, Ahjond S. Garmestani, Lance H. Gunderson, Olle Hjerne, Monika Winder

Nebraska Cooperative Fish & Wildlife Research Unit -- Staff Publications

The adaptive cycle was proposed as a conceptual model to portray patterns of change in complex systems. Despite the model having potential for elucidating change across systems, it has been used mainly as a metaphor, describing system dynamics qualitatively. We use a quantitative approach for testing premises (reorganisation, conservatism, adaptation) in the adaptive cycle, using Baltic Sea phytoplankton communities as an example of such complex system dynamics. Phytoplankton organizes in recurring spring and summer blooms, a well-established paradigm in planktology and succession theory, with characteristic temporal trajectories during blooms that may be consistent with adaptive cycle phases. We used long-term ...


Meeting Calendar Dec 2015

Meeting Calendar

Journal of Medicinally Active Plants

No abstract provided.


Therapeutic Raavrh10 Mediated Sod1 Silencing In Adult Sod1g93a Mice And Nonhuman Primates, Christian Mueller Dec 2015

Therapeutic Raavrh10 Mediated Sod1 Silencing In Adult Sod1g93a Mice And Nonhuman Primates, Christian Mueller

Christian Mueller

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease; survival in ALS is typically 3–5
years. No treatment extends patient survival by more than three months. Approximately 20% of familial
ALS and 1–3% of sporadic ALS patients carry a mutation in the gene encoding superoxide dismutase 1
(SOD1). In a transgenic ALS mouse model expressing the mutant SOD1G93A protein, silencing the SOD1
gene prolongs survival. One study reports a therapeutic effect of silencing the SOD1 gene in systemically
treated adult ALS mice; this was achieved with a short hairpin RNA, a silencing molecule that has raised
multiple safety ...


Prevalence And Predictors Of Pre-Diabetes And Diabetes Among Adults 18 Years Or Older: A Multinomial Logistic Modeling Approach, Agricola Odoi, Ifechukwude O. Okwechime Dec 2015

Prevalence And Predictors Of Pre-Diabetes And Diabetes Among Adults 18 Years Or Older: A Multinomial Logistic Modeling Approach, Agricola Odoi, Ifechukwude O. Okwechime

Agricola Odoi

BACKGROUND:
Individuals with pre-diabetes and diabetes have increased risks of developing macro-vascular complications including heart disease and stroke; which are the leading causes of death globally. The objective of this study was to estimate the prevalence of pre-diabetes and diabetes, and to investigate their predictors among adults ≥18 years in Florida.
METHODS:
Data covering the time period January-December 2013, were obtained from Florida's Behavioral Risk Factor Surveillance System (BRFSS). Survey design of the study was declared using SVYSET statement of STATA 13.1. Descriptive analyses were performed to estimate the prevalence of pre-diabetes and diabetes. Predictors of pre-diabetes and ...


Lung Cancer And Mesothelioma, Jeffrey A. Gordon, Elizabeth Kurian, Arash Bedayat, Ali Akalin, Karl Uy, Richard S. Pieters Dec 2015

Lung Cancer And Mesothelioma, Jeffrey A. Gordon, Elizabeth Kurian, Arash Bedayat, Ali Akalin, Karl Uy, Richard S. Pieters

Cancer Concepts: A Guidebook for the Non-Oncologist

This chapter in Cancer Concepts: A Guidebook for the Non-Oncologist presents an overview of lung cancer and mesothelioma, including epidemiology, etiology, screening, pathology, staging, and treatment.


Alternative Use Of Dna Binding Domains By The Neurospora White Collar Complex Dictates Circadian Regulation And Light Responses, Bin Wang, Xiaoying Zhou, Jennifer J. Loros, Jay C. Dunlap Dec 2015

Alternative Use Of Dna Binding Domains By The Neurospora White Collar Complex Dictates Circadian Regulation And Light Responses, Bin Wang, Xiaoying Zhou, Jennifer J. Loros, Jay C. Dunlap

Open Dartmouth: Faculty Open Access Articles

In the Neurospora circadian system, the White Collar complex (WCC) of WC-1 and WC-2 drives transcription of the circadian pacemaker gene frequency (frq), whose gene product, FRQ, as a part of the FRQ-FRH complex (FFC), inhibits its own expression. The WCC is also the principal Neurospora photoreceptor; WCC-mediated light induction of frq resets the clock, and all acute light induction is triggered by WCC binding to promoters of light-induced genes. However, not all acutely light-induced genes are also clock regulated, and conversely, not all clock-regulated direct targets of WCC are light induced; the structural determinants governing the shift from WCC ...


Amyloid Proteins Structure, Dynamics, Interactions And Early Stages Of Self-Assembly, Yuliang Zhang Dec 2015

Amyloid Proteins Structure, Dynamics, Interactions And Early Stages Of Self-Assembly, Yuliang Zhang

Theses & Dissertations

The self-assembly and aggregation of amyloid protein are associated with several neurodegenerative diseases. The evidence indicates that the oligomeric intermediates, formed prior to the final fibrillary product, are the primary culprits of neurotoxicity. Although tremendous efforts have been dedicated for the characterization of structures, dynamics and toxic-related hallmarks of the oligomers, to date, yet the mechanism of such assembly from disordered monomers and their structure remain elusive.

In this dissertation, I focused on understanding the dimerization process of amyloid proteins and peptides of different sizes and I combined experimental studies with high-power computer simulations. The AFM force spectroscopy experiments showed ...


Consequences Of Shifts In Abundance And Distribution Of American Chestnut For Restoration Of A Foundation Forest Tree, Harmony J. Dalgleish, Charles Dana Nelson, John A. Scrivani, Douglass F. Jacobs Dec 2015

Consequences Of Shifts In Abundance And Distribution Of American Chestnut For Restoration Of A Foundation Forest Tree, Harmony J. Dalgleish, Charles Dana Nelson, John A. Scrivani, Douglass F. Jacobs

Forestry and Natural Resources Faculty Publications

Restoration of foundation species, such as the American chestnut (Castanea dentata) that was devastated by an introduced fungus, can restore ecosystem function. Understanding both the current distribution as well as biogeographic patterns is important for restoration planning. We used United States Department of Agriculture Forest Service Forest Inventory and Analysis data to quantify the current density and distribution of C. dentata. We then review the literature concerning biogeographic patterns in C. dentata. Currently, 431 ± 30.2 million stems remain. The vast majority (360 ± 22 million) are sprouts < 2.5 cm dbh. Although this number is approximately 10% of the estimated pre-blight population, blight has caused a major shift in the size structure. The current-day population has a larger range, particularly west and north, likely due to human translocation. While climate change could facilitate northward expansion, limited seed reproduction makes this unlikely without assisted migration. Previous research demonstrates that the current, smaller population contains slightly higher genetic diversity than expected, although little information exists on biogeographic patterns in the genetics of adaptive traits. Our research provides a baseline characterization of the contemporary population of C. dentata, to enable monitoring stem densities and range limits to support restoration ...


A Genetic And Biochemical Analysis Of Sulfolobus Spindle-Shaped Virus 1, Eric Alexander Iverson Dec 2015

A Genetic And Biochemical Analysis Of Sulfolobus Spindle-Shaped Virus 1, Eric Alexander Iverson

Dissertations and Theses

Viruses infecting the Archaea exhibit a tremendous amount of morphological and genetic diversity. This is especially true for crenarchaeal viruses from the family Fuselloviridae, which possess spindle-shaped capsids and genomes that harbor a great number of uncharacterized genes. The functions of these unidentified gene products are of interest as they have the potential to provide valuable insights into the fusellovirus infection cycle and archaeal viruses in general. In an effort to better characterize the genetic requirements of the Fuselloviridae, we have performed genetic and biochemical experiments using the best studied fusellovirus, Sulfolobus spindle-shaped virus 1 (SSV1).

A comprehensive genetic analysis ...


Vestigial Serrula In Scorpion Genera Paravaejovis, , Smeringurus And Vejovoidus (Scorpiones: Vaejovidae), Victor Fet, Michael E. Soleglad, Michael S. Brewer, David P. A. Neff, Michael L. Norton Dec 2015

Vestigial Serrula In Scorpion Genera Paravaejovis, , Smeringurus And Vejovoidus (Scorpiones: Vaejovidae), Victor Fet, Michael E. Soleglad, Michael S. Brewer, David P. A. Neff, Michael L. Norton

Euscorpius

The presence of vestigial serrula on the ventral edge of the cheliceral movable finger is established for vaejovid genera Paravaejovis, Paruroctonus, Smeringurus, and Vejovoidus. Detailed descriptions and SEM images illustrating the various manifestations of this interesting cheliceral structure are provided for many species of these four genera. A brief systematic overview of this structure as it exists in Recent scorpions is also presented.


Serrula In Retrospect: A Historical Look At Scorpion Literature (Scorpiones: Orthosterni), Matthew R. Graham, Victor Fet Dec 2015

Serrula In Retrospect: A Historical Look At Scorpion Literature (Scorpiones: Orthosterni), Matthew R. Graham, Victor Fet

Euscorpius

Serrula, a small comb-like structure on the ventral aspect of cheliceral movable finger in scorpions, has often been overlooked or ignored. Scorpion genera that are currently known to possess serrula belong to six families: Chactidae, Euscorpiidae, Iuridae, Pseudochactidae, Superstitioniidae, and Vaejovidae. All relevant literature on scorpion serrula is reviewed, and serrula of representative scorpion taxa is illustrated by SEM images. We suggest that the inconsistency in reporting serrula is based on several factors (or combination thereof): (a) serrula tines can quite often be broken off partially or completely, especially in adults; (b) serrula can be vestigial and hardly visible under ...


On The Poorly Known Genus Mesotityus González-Sponga, 1981 (Scorpiones: Buthidae), Luis F. De Armas, Fernando J. M. Rojas-Runjaic Dec 2015

On The Poorly Known Genus Mesotityus González-Sponga, 1981 (Scorpiones: Buthidae), Luis F. De Armas, Fernando J. M. Rojas-Runjaic

Euscorpius

Examination of new available material (18 females and six males) of the rare Venezuelan scorpion Mesotityus vondangeli González-Sponga, 1981 (Buthidae) demonstrated that there are consistent taxonomic characters to consider it as a genus different from Tityus C. L. Koch, 1836 sensu stricto. Nevertheless, it shares important characters with species of the Tityus clathratus group (=subgenus Archaeotityus Lourenço, 2006). An emended diagnosis of Mesotityus is given, as well as data on natural history, meristic and morphometric variation.


From Lab To Pharmacy Shelves: The Story Of A Plant Derived Anticancer Drug, "Paclitaxel", Maira Junjua, Sana Jafar, Fazeelat Karamat, Faheem Ahmed Dec 2015

From Lab To Pharmacy Shelves: The Story Of A Plant Derived Anticancer Drug, "Paclitaxel", Maira Junjua, Sana Jafar, Fazeelat Karamat, Faheem Ahmed

Journal of Bioresource Management

Paclitaxel (Taxol®) is a highly praised anticancer drug, known for its efficiency in treating different cancers. It belongs to a class of compounds called taxanes that are derived from the plants of the genus Taxus. This drug is now FDA approved, but there was a time when the name Taxol was less known to the scientific world. Taxol, being a unique molecule in its structure, properties and mechanism of action, has undergone more than 30 years of trials, and faced a lot of hurdles to leave the bench of a laboratory and reach the shelves of a pharmacy. This review ...


Anthropogenic Influences On The Tolipir Landscape, Lesser Himalayas, Pakistan, Abu -Ul- Hassan Faiz, Fakhar -I- Abbas, Lariab Zahra, Sadaf Hanif Dec 2015

Anthropogenic Influences On The Tolipir Landscape, Lesser Himalayas, Pakistan, Abu -Ul- Hassan Faiz, Fakhar -I- Abbas, Lariab Zahra, Sadaf Hanif

Journal of Bioresource Management

The present study describes anthropogenic pressure in the Tolipir landscape of the lesser Himalayas. The GIS tools, questionnaire and field sampling surveys were used to estimate threats in landscape. The study was conducted in January 2013 to January 2014.The five model villages (Ali Saujal, Kanchi Kot, Khori Chana, Kahoo Kot, Noor Kot) of Tolipir landscape were selected to determine anthropogenic pressure. The study documents that Tolipir landscape has an average number of houses (350 ± 82.4), with number of individuals per house (10.8 ± 1.1) and fuel consumption per day (43.72±3.30 kg). The preferred fuel ...


Status And Future Management Of Grey Goral (Naemorhedus Goral Bedfordi) In Pakistan, Fakhar -I- Abbas, Afsar Mian, Tanveer Akhtar, Thomas P. Rooney Dec 2015

Status And Future Management Of Grey Goral (Naemorhedus Goral Bedfordi) In Pakistan, Fakhar -I- Abbas, Afsar Mian, Tanveer Akhtar, Thomas P. Rooney

Journal of Bioresource Management

Himalayan grey goral (HGG: Naemorhedus goral bedfordi) is endemic to Himalyas and regarded as Endangered/ Threatened. Study was designed to collect information on population biology, habitat, food and behaviour of population of HGG distributed in Pakistan, trying to understand its present status and conservational potentials. Our data suggest that the population, habitat and the species has sufficient potentials for its survival in the area, if protection from human predation is afforded to the species. HGG population is isolated into 7-8 subpopulations and is facing male-biased mortality, therefore is likely to face bottleneck effects and subsequent population crash ascribed to loss ...


Dna Protective Activity Of Peels Of Some Vegetables Wastes, Aisha Ishaq, Kainaat William Dec 2015

Dna Protective Activity Of Peels Of Some Vegetables Wastes, Aisha Ishaq, Kainaat William

Journal of Bioresource Management

The present study was conducted by using kitchen wastes like peels of different vegetables e.g. cucumber, potato, carrot, chickpea, cauliflower and pea, to evaluate the phytochemical constituents, DNA protection ability and free radicals scavenging activity. Phytochemicals tests showed the presence of carbohydrates, amino acids, glycosides, alkaloids, tannins and steroids in all samples while phlobatannins, anthraquonines and saponins were absent. The DNA protection of samples was checked by DNA protection assay using plasmid pBR322. Cauliflower and cucumber showed best protection at each dilution. DPPH free radicals scavenging assay was used to evaluate the antioxidant activity of peel extract of vegetables ...


Taxonomic Position Of The Genus Sassanidotus Farzanpay, 1987 (Scorpiones: Buthidae), František Kovařík, Victor Fet Dec 2015

Taxonomic Position Of The Genus Sassanidotus Farzanpay, 1987 (Scorpiones: Buthidae), František Kovařík, Victor Fet

Euscorpius

Sassanidotus Farzanpay, 1987 is a valid genus closely related to Compsobuthus Vachon, 1949, with which it shares most characters including the shape of carinae on the carapace and mesosoma. The main difference is that Sassanidotus has only three granules located proximally to the terminal granule on the movable finger of pedipalp, whereas Compsobuthus and also Mesobuthus Vachon, 1950 have four such granules. Sassanidotus Farzanpay, 1987 includes two species, Sassanidotus zarudnyi (Birula, 1900) (type species) from Iran and Sassanidotus gracilis thus zarudnyi sarghadensis Birula, 1903, syn. n.) from Afghanistan, Iran, and Pakistan. The neotype is designated for S. zarudnyi.


Protection Against Experimental Cryptococcosis Following Vaccination With Glucan Particles Containing Cryptococcus Alkaline Extracts, Charles A. Specht, Chrono K. Lee, Haibin Huang, Donald J. Tipper, Zu T. Shen, Jennifer K. Lodge, John D. Leszyk, Gary R. Ostroff, Stuart M. Levitz Dec 2015

Protection Against Experimental Cryptococcosis Following Vaccination With Glucan Particles Containing Cryptococcus Alkaline Extracts, Charles A. Specht, Chrono K. Lee, Haibin Huang, Donald J. Tipper, Zu T. Shen, Jennifer K. Lodge, John D. Leszyk, Gary R. Ostroff, Stuart M. Levitz

Infectious Diseases and Immunology Publications and Presentations

A vaccine capable of protecting at-risk persons against infections due to Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global burden of human cryptococcosis. Vaccine development has been hampered though, by lack of knowledge as to which antigens are immunoprotective and the need for an effective vaccine delivery system. We made alkaline extracts from mutant cryptococcal strains that lacked capsule or chitosan. The extracts were then packaged into glucan particles (GPs), which are purified Saccharomyces cerevisiae cell walls composed primarily of β-1,3-glucans. Subcutaneous vaccination with the GP-based vaccines provided significant protection against subsequent pulmonary infection with highly virulent ...


U.S. Drought Monitor, December 22, 2015, Richard R. Heim Jr. Dec 2015

U.S. Drought Monitor, December 22, 2015, Richard R. Heim Jr.

US Ag in Drought Archive

Drought map of U.S. for December 22, 2015 (12/22/15) plus: U.S. crop areas experiencing drought (map), Approximate percentage of crop located in drought, by state (bar graph), Percent of crop area located in drought, past 52 weeks (line graph) for: Corn, Soybeans, Hay, Cattle, Winter wheat.