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Articles 1 - 30 of 95

Full-Text Articles in Biomedical Engineering and Bioengineering

Kinematics During Knee Extension, Lunge, And Chair Rise, Center For Orthopaedic Biomechanics, Kevin Shelburne, Phd, Michael D. Harris, Phd, Vasiliki Kefala, Donald R. Hume, Bradley S. Davidson, A. J. Cyr, R. H. Kim, A. A. Ali, E. M. Mannen Apr 2019

Kinematics During Knee Extension, Lunge, And Chair Rise, Center For Orthopaedic Biomechanics, Kevin Shelburne, Phd, Michael D. Harris, Phd, Vasiliki Kefala, Donald R. Hume, Bradley S. Davidson, A. J. Cyr, R. H. Kim, A. A. Ali, E. M. Mannen

Living Kinematics of the Knee

No abstract provided.


Fall 2018 Biomedical Engineering Newsletter, Department Of Biomedical Engineering, Michigan Technological University Oct 2018

Fall 2018 Biomedical Engineering Newsletter, Department Of Biomedical Engineering, Michigan Technological University

Department of Biomedical Engineering Newsletters

Table of Contents

  • Global Research, Local Impact: Keat Ghee Ong
  • Mechanobiology: Sangyoon Han Measures Cellular Force
  • Rupak Rajachar Accelerates Healing in Humans - and Whales
  • Optical Elastography Gathers Better Data for Avon
  • Making Stents: NSF Graduate Research Fellow Roger Guillory


A Metabolomic Approach To Diagnosing Prosthetic Joint Infection, Victor Borza, Christian A. Rees, Douglas W. Van Citters, Jane E. Hill May 2018

A Metabolomic Approach To Diagnosing Prosthetic Joint Infection, Victor Borza, Christian A. Rees, Douglas W. Van Citters, Jane E. Hill

Wetterhahn Science Symposium Prize Winning Posters

No abstract provided.


Optimal Surgical Plating Of Mandibular Angle Fractures: A Validated Finite Element Model, Brett Seeley-Hacker May 2018

Optimal Surgical Plating Of Mandibular Angle Fractures: A Validated Finite Element Model, Brett Seeley-Hacker

Wetterhahn Science Symposium Prize Winning Posters

No abstract provided.


No-Releasing Polymers And Uses Thereof, Megan C. Frost, Genevieve Romanowicz Feb 2018

No-Releasing Polymers And Uses Thereof, Megan C. Frost, Genevieve Romanowicz

Michigan Tech Patents

The present invention provides stable, photosensitive polymers that release NO response to intensity and wavelength of light, methods of making such polymers and methods using such polymers.


Using Crosslinked Hyaluronic Acid (Ha) And Collagen Scaffolds With Sustained Brain-Derived Neurotrophic Factor (Bdnf) Release For Post-Sci Nerve Regeneration, Panth Doshi Jan 2018

Using Crosslinked Hyaluronic Acid (Ha) And Collagen Scaffolds With Sustained Brain-Derived Neurotrophic Factor (Bdnf) Release For Post-Sci Nerve Regeneration, Panth Doshi

Undergraduate Research Posters

Traumatic events resulting in spinal cord injuries (SCIs) often leave people paralyzed or with partial loss of motor function. The physical disabilities arising from traumatic events prevent people from functioning at the same level as pre-injury. My work aims to identify a plausible method to overcome the inhibitory post-SCI environment and to regenerate nervous tissue in order to restore neural function and, subsequently, motor function. I identified components of a new, hypothetical nerve scaffold based on the immune response after SCIs and the efficacy of currently used scaffolds for nerve regeneration. Hyaluronic acid (HA) polymer scaffolds and collagen-based scaffolds are ...


Designing Biomaterials Using Mussel Adhesive Chemistry, Bruce P. Lee Oct 2017

Designing Biomaterials Using Mussel Adhesive Chemistry, Bruce P. Lee

TechTalks

Marine mussels secrete adhesive proteins that enable them to anchor to surfaces under water. We are exploiting chemistry utilized by mussels to design bioadhesives for tissue repair and wound healing, smart biomaterials for on-demand antipathogenic applications, and smart adhesives that can be turned on and off with externally applied stimuli.


The Subject Librarian Newsletter, Engineering And Computer Science, Fall 2017, Buenaventura "Ven" Basco Aug 2017

The Subject Librarian Newsletter, Engineering And Computer Science, Fall 2017, Buenaventura "Ven" Basco

Libraries' Newsletters

No abstract provided.


Biomechanics And Imaging, Jingfeng Jiang Mar 2017

Biomechanics And Imaging, Jingfeng Jiang

TechTalks

From the perspective of biomechanics, my research is multidisciplinary, bridging the gap between physiology/biology and quantitative sciences. Currently, the applications are on cancer detection and differentiation, therapeutic monitoring, staging liver fibrosis, risk assessment of aneurysm rupture, and more.


Implantable Sensors For Regenerative Medicine, Keat Ghee Ong Mar 2017

Implantable Sensors For Regenerative Medicine, Keat Ghee Ong

TechTalks

In vivo, real-time measurement of local environmental parameters such as strain, pressure, temperature, pH, oxygen tension and specific biomarkers can be valuable for regenerative medicine research and therapies. Wireless implantable sensors are an attractive approach for certain regenerative medicine applications due to its relative simplicity and low cost. Presented here are such two implantable sensors. The first sensor is based on a miniature wireless sensor network that can digitize physical and chemical parameters and continuously stream measurements to a nearby receiver via a 2-way communication protocol. With the incorporation of a strain gauge, this sensor platform was applied to record ...


Biodegradable Zinc Vascular Implant Materials, Jeremy Goldman Mar 2017

Biodegradable Zinc Vascular Implant Materials, Jeremy Goldman

TechTalks

Bioabsorbable metal stents are being developed to mitigate the long-term side effects associated with corrosion-resistant stents. A decade-long research with iron (Fe)- and magnesium (Mg)-based stent materials has concluded with little success. Fe produces a voluminous, retained oxide product in the arterial wall, whereas Mg and its alloys corrode too rapidly. A breakthrough in the field of biodegradable metallic stents was made in 2013 in our research team (Drs. Goldman – Biomedical Engineering and Drelich – Materials Science and Engineering) with the introduction of zinc (Zn) and its alloys, which are free of the flaws observed for Fe- and Mg-based alloys ...


Low Cost, Adhesion Strength Based Cell Sorter, Emily Burtch, Franck Kamga-Gninzeko, Devin Mair, Sarah Saunders Jan 2017

Low Cost, Adhesion Strength Based Cell Sorter, Emily Burtch, Franck Kamga-Gninzeko, Devin Mair, Sarah Saunders

Capstone Design Expo Posters

In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells. Recently, it was discovered that different cell types adhere to cell culture dishes at different strengths. This observation was utilized in the invention of a cell sorting system that sorts cells based on this adhesion strength difference. The resulting system is marketable at under $2000, compared to $50000 plus for current commercially available systems, and is the first commercially-oriented cell adhesion strength based cell ...


Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee Jan 2017

Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee

Undergraduate Research Posters

The ECGs I micro-fabricate are designed to be flexible, stretchable and wireless circuits that can be applied to the skin directly. The device is encased in a conformal, silicon-like substrate, that allows the ECG to be attached with the electrodes. Each electrode has been previously measured and verified that it will be correctly placed for an accurate reading. Prototyping this ECG/electrode device allows the user to mount the prototype directly to the patient without having to attach and wire ten other electrodes. This prototype solves the issue that comes about when a doctor, nurse or emergency medical technician must ...


Stem Cell And Tissue Engineering Research, Feng Zhao Dec 2016

Stem Cell And Tissue Engineering Research, Feng Zhao

TechTalks

My research focuses on stem cell and tissue engineering. By combining stem cell biology and engineering tools, the Zhao Lab seeks strategies to biofabricate completely biological tissues to regenerate or repair damaged tissues or organs. The function of engineered tissues is being strengthened by recapitulating the in vivo environment of natural tissues. The underlying mechanism is being explored through investigating the interaction of cells with environmental factors such as topographical cues, biophysical forces, and oxygen tensions. We also prompt stem cell research at Michigan Tech to meet the progress and advance of the outside scientific society. Training opportunities are consistently ...


Point-Of-Care Microfluidic Device For Blood Typing, Hector Moncada-Hernandez Nov 2016

Point-Of-Care Microfluidic Device For Blood Typing, Hector Moncada-Hernandez

TechTalks

There has been increasing efforts to translate laboratory blood tests analysis into portable, reliable, and cheap miniaturized devices. Electrokinetic-based microfluidic devices provide a new approach to blood tests with a simple infrastructure for the manipulation of cells. Previous studies show red blood cells’ (RBC) dielectrophoretic response changes based on the different ABO-Rh antigens present in the cells membrane. In this research, an alternate-current electric signal with a frequency sweep (0.1 – 1 MHz) is applied through an array of electrodes to generate non-uniform electric fields and induce dielectrophoretic forces on RBC from all eight blood types. The RBC’s response ...


Spring 2016 Biomedical Engineering Newsletter, Department Of Biomedical Engineering, Michigan Technological University Apr 2016

Spring 2016 Biomedical Engineering Newsletter, Department Of Biomedical Engineering, Michigan Technological University

Department of Biomedical Engineering Newsletters

Table of Contents

  • Focus on Cardiovascular Research
  • BMES Rising Star Feng Zhao
  • Magnetoelastic: Sensing more with less
  • Portage Health/Michigan Tech Partnership
  • Remembering Dr. Michael Neuman


Design Of A Drug Delivery System Through The Gastrointestinal Tract, Kaixin Chen, Adel Husayni, Kayvon Mobarakeh, Ankit Soni Jan 2016

Design Of A Drug Delivery System Through The Gastrointestinal Tract, Kaixin Chen, Adel Husayni, Kayvon Mobarakeh, Ankit Soni

Capstone Design Expo Posters

Alzheimer’s Disease (AD) afflicts an estimated 5.3 million individuals and is the sixth leading cause of death in America. The drug delivery method of interest is an orally administered sustained-release delivery system that addresses the needs of the associated patient population. By augmenting drug delivery with a higher effective payload per dose compared to current methods, drug efficacy and bioavailability would improve. This will result in a decrease of the overall cost for medication as a greater percentage of the administered drug will be viable.

This design addresses the release of AD drug from the drug delivery system ...


Catheter Attachment Device For Prevention Of Urinary Tract Infection, Ashleigh Mccormick, Brittany Allen, Karolina Stumbraite, Kevin Ball Jan 2016

Catheter Attachment Device For Prevention Of Urinary Tract Infection, Ashleigh Mccormick, Brittany Allen, Karolina Stumbraite, Kevin Ball

Capstone Design Expo Posters

Hospital-acquired infections are costly occurrences that cause patients physical discomfort, have dangerous immune consequences, and cost healthcare providers hundreds of millions of dollars every year in liability fees and negligence charges. Catheter associated urinary tract infections (CAUTI) are the most common class of hospital-acquired infection, affecting over half a million patients in U.S. hospitals alone every year.The CAUTI-Guard team has designed a silver-coated polydimethylsiloxane (PDMS) plug device that helps prevent CAUTI through its action as a physical and chemical block. The device slides along standard urinary catheters and helps block the migration of infectious material into the urethra ...


Improved Device For Passive Foot Dorsiflexion For Prevention Of Dvt, Stephen Vinoba, Nigal Shah, Shreya Vatsala, Jawahar Baddula Jan 2016

Improved Device For Passive Foot Dorsiflexion For Prevention Of Dvt, Stephen Vinoba, Nigal Shah, Shreya Vatsala, Jawahar Baddula

Capstone Design Expo Posters

Postoperative patients are often too fatigued to walk around and often lay in bed for extended periods of time. This could lead to the development of deep vein thrombosis (DVT). DVT is a condition where blood accumulates in the veins instead of being pushed back to the heart. This can cause the formation of blood clots that can eventually lead to pulmonary embolism resulting in death. DVT is a condition that affects about 900,000 people in the United States. Since it is such a prevalent condition, it is important to develop methods of prevention for this condition.

The aim ...


Mri Hip Joint Traction Device, Rawan Alfadly, Carla Gomez, Sara Um Jan 2016

Mri Hip Joint Traction Device, Rawan Alfadly, Carla Gomez, Sara Um

Capstone Design Expo Posters

Radiologists commonly use contrast agents to improve resolution and acuity when employing MRI (Magnetic Resonance Imaging). Introducing MRI contrast agents to the tissue in the innermost part of the femoroacetabular joint is extremely difficult because the anatomy prevents the contrast agents from infiltrating those surfaces. Therefore, getting the ideal image resolution and making diagnosis of the hip is difficult. The objective was to design a product that would successfully distract one hip joint while also stabilizing the patient’s pelvis to improve visualization so that physicians are able to better diagnose the hip. The deliverables included a preliminary model that ...


Small Animal Thermal Support Device: Thermoregulation System For Scireq Flexivent Chamber, Alexander Dickey, Ashkhan Hojati, Matthew James, Kathleen Vermillera Jan 2016

Small Animal Thermal Support Device: Thermoregulation System For Scireq Flexivent Chamber, Alexander Dickey, Ashkhan Hojati, Matthew James, Kathleen Vermillera

Capstone Design Expo Posters

During ventilation induced lung injury (VILI) experiments, anesthetized mice lose the ability to regulate their core body temperature. Without maintaining homeostasis, the experimental data may be compromised due to changes in the rodent’s internal functions. Traditional heating techniques utilize a water circulation heating system that is unable to fit inside flexiVent ventilator testing chambers. The objective of this project is to design and build an automatic thermoregulatory feedback system to regulate the core body temperature of a mouse inside individual testing chambers throughout the duration of the experiment. The project deliverables include a functioning prototype that achieves safe and ...


Pulmonary Patency Stent, Kranthidhar Bathula, Suraj Kandalam, Akhil Kolluri, Roshni Malik Jan 2016

Pulmonary Patency Stent, Kranthidhar Bathula, Suraj Kandalam, Akhil Kolluri, Roshni Malik

Capstone Design Expo Posters

Patients with malignancies in the central airways often experience significant breathing difficulties due to occlusion of the airways. One common palliative treatment option for this is a stent placement procedure. While patients often experience immediate symptom relief, long term use can result in the formation of granulation tissue, causing restenosis of the airway. The objective of this project is to design and prototype a modification to the Boston Scientific Ultraflex partially-covered stent in order to reduce granulation tissue and maintain airway patency. Deliverables include the detailed design, a working prototype, and supporting data. The main product specifications include effectiveness in ...


Minimizing Loss Of Balance And Falls With Personal Walkers, Michael Berger, Galen Kellner, David Le, Anthony Renninger Jan 2016

Minimizing Loss Of Balance And Falls With Personal Walkers, Michael Berger, Galen Kellner, David Le, Anthony Renninger

Capstone Design Expo Posters

Falls within the Older Adult community lead to roughly 734,000 hospital admissions annually with 87% attributed to walker use. In order to reduce the amount of falls due to walker use our objective was to create a system that detects an increased likelihood of a fall occurring, notifies the user of improper positioning, and can intervene by application of an automatic braking system to stabilize the walker; effectively training the user to have a more proper walking form and posture reducing the risk of a fall. In order to accomplish this goal, final deliverables included a working prototype and ...


Sensing Movement In Endotracheal Tubes, Mary Anisa Kannan, Krista Powell, Navami Ravindra, Tiffany Wong Jan 2016

Sensing Movement In Endotracheal Tubes, Mary Anisa Kannan, Krista Powell, Navami Ravindra, Tiffany Wong

Capstone Design Expo Posters

The objective of this project was to develop a device that would better secure endotracheal tubes (ETT), measure unwanted displacement, and notify caretakers when a dangerous amount of displacement has occurred. The project deliverables were as follows: a detailed design, a prototype, and a final demonstration of the prototype which shows successful ability to carry out the objectives stated above. The device needs to be small in size, expensive, flexible to allow for regular cleaning, yet strong enough to withstand stress. The final design consists of a small bite block holder and head straps to secure the device. The device ...


Marsupialization Catheter, Hamdi Abdeen, Ananya Mishra, Lucas Olson, Jacqueline Pinderski Jan 2016

Marsupialization Catheter, Hamdi Abdeen, Ananya Mishra, Lucas Olson, Jacqueline Pinderski

Capstone Design Expo Posters

A significant issue among oral and maxillofacial surgeons is the treatment of cysts within the jaw. Cysts develop at random and in most cases asymptomatically. Therefore, they may reach enormous sizes before being diagnosed. Large cysts can cause severe damage to teeth and the surrounding bone. Doctors treat small cysts by surgically removing them. However, this approach is not ideal for large cysts due to the risk of surgical complications, the high expenses incurred, and the fact that it is often undesired by the patient. Current treatments include surgically opening the cyst and either suturing the tissue open or placing ...


Suture Trainer: Improving Tissue Handling Technique, Albara Elshaer, Sindora Baddam, Veronica Peterkin, Millie Shah Jan 2016

Suture Trainer: Improving Tissue Handling Technique, Albara Elshaer, Sindora Baddam, Veronica Peterkin, Millie Shah

Capstone Design Expo Posters

Tissue handling is fundamental to performing mechanical tasks of suturing and surgery on live humans and animals. While the mechanics of suturing can be taught, there is no available simulation product designed to specifically teach tissue handling skills. It is important as a future medical professional to gain better tissue handling skills in order to prevent unnecessary injury to the tissue via scarring. The suture trainer focuses on providing feedback in order to standardize tissue handling technique in order to prevent poor habits from developing. Our project deliverables included a model, working prototype, and test data collected from practicing physicians ...


A Tilting System For Powered Wheelchairs, Liam Cornwall, Brandon Heath, Justin Mcdaniel, Alexander Stevenson Jan 2016

A Tilting System For Powered Wheelchairs, Liam Cornwall, Brandon Heath, Justin Mcdaniel, Alexander Stevenson

Capstone Design Expo Posters

The objective of our project is to create a wheelchair platform that can tilt a power wheelchair and its user back into a nearhorizontal position. The purpose of this is to allow a dentist to work on the patient in the manner and position with which they are most accustomed.

The device currently used by our sponsor, The Virginia Home, is the Versatilt platform. The Versatilt is capable of lifting a maximum weight of 750 lbs. and tilting patients back, up to 65 degrees. However, the platform is too small to accept the power wheelchairs used by the majority of ...


Iv Pole For Cardiac Surgery, Sindhu Marampudi, Natalie Noll, Madison Nowak, Rachel Wilbur Jan 2016

Iv Pole For Cardiac Surgery, Sindhu Marampudi, Natalie Noll, Madison Nowak, Rachel Wilbur

Capstone Design Expo Posters

IV lines and pumps need to be transported from the operating room to patient recovery with the patient after cardiac procedures. During this process, the weight of the IV pumps and the small wheels on the IV pole can cause the IV pole to become unbalanced and fall or bend due to the load. Due to a decrease in slack in IV lines to minimize IV line tangling, when an IV pole falls, this can result in the IV lines being torn out of the patient that can lead to blood loss and other injuries. In addition, IV bags and ...


Low Cost Sterilization, Karima Abutaleb, Mahreen Azam, Eric Lara, Sarah Tracy Jan 2016

Low Cost Sterilization, Karima Abutaleb, Mahreen Azam, Eric Lara, Sarah Tracy

Capstone Design Expo Posters

The lack of proper surgical tool sterilization is an increasing issue in developing countries. Inadequate sterilization leads to disease transmission, infection and even death. While autoclaves, the current golden standard for sterilization, are effective, they are often rendered useless after breaking as the cost to repair and maintain them is incredibly high. This leads to the dependence on insufficient techniques such as the use of diluted bleach. Diluted bleach, while effective for disinfection, leads to the destruction of surgical tools over time, does not destroy spores, and is unsustainable, as it loses potency over time which leads to its otherwiseunnecessary ...


Prediction Device To Reduce Falls In The Elderly, Keegan Zacharie, Aaron Corbin, Joseph Switzer Jan 2016

Prediction Device To Reduce Falls In The Elderly, Keegan Zacharie, Aaron Corbin, Joseph Switzer

Capstone Design Expo Posters

Complications arising from accidental falls are one of the leading causes of death among the elderly, with over 25,000 fatalities annually in the U.S.; a third of the elder population falls each year and a fifth of falls cause serious injury. We intended to mitigate these risks by producing a device capable of anticipating falls using biostatistical data.

Deliverables for our design included: An integrated accelerometer and pulse monitor to assess changes in motion and the physiological state of the wearer, a programmed algorithm capable of processing this data, and a mount to attach components to the patient ...